Welcome to today's live podcast with Evan Brand! In this podcast, the functional duo educates people about what Collagen is, why is it important and where it originates. Watch as they also explain how one loses Collagen and what affects it. Also, listen as they enumerate the different types of Collagen and other related things like gut health, deficiencies, etc.
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Dr. Justin Marchegiani
In this episode, we cover:
01:28 Decreasing Collagen Exposure
04:36 Tryptophan Absence, Skin Health, and Collagen Matrix
15:50 Gut Health Affecting Joint Health
16:30 Cortisol: The “Anti-Bone Broth”
19:00 The Evolution of the Human Brain
Dr. Justin Marchegiani: Evan, it’s Dr. J here in the house. How are we doing, man? How’s your Monday?
Evan Brand: happy Monday to you, man. I’m back on the grind. I took last week off. I told you it was crazy like working so hard and then just coming to a— uh— a standstill. It was difficult for me. Now, once I got to the end of the week, I started to relax. But, man, I tell you,
Dr. Justin Marchegiani: Yeah. I mean, when you have jobs like we do, where you really, really enjoy. It’s uh— It’s fun to be living on purpose and helping people.
Evan Brand: Yup. Agreed.
Dr. Justin Marchegiani: Totally.
Evan Brand: Well, you came up with a great topic idea, which is all about Collagen. And— I mean, I can’t tell you how many women, when I’m asking them about their supplements— Like, random women, that may or may not know anything about health or functional medicine— somehow they discovered Collagen, and they’re taking it as a supplement. But, before we get
Dr. Justin Marchegiani: Yeah, absolutely. So, Collagen’s important. One of my favorite a— amino acid that I love to supplement at least once, even twice a day. I typically do it, in the morning, in my coffee and I do it at night in— with some Magnesium citrate powder. I love it. We typically get exposure to Collagen, Collagen amino acids, in the environment through connective tissue support, so like bone broths, where we can get the full bone and the Collagen and— and the ligament, its tendon, and the high to the skin of the animal. So, most of the time, we’re just not getting that exposure these days ‘cause we’re just eating muscle meat, and most of the time, it’s even skinless. And we’re not doing it any broth form. We’re not doing any soup. So, we’re not getting a lot of the marrow, the ligaments, the tendon, the cartilage, amino acids. So, we’re getting
Evan Brand: That’s amazing! So, I’m just reading a little bit about hydrolyzed Collagen, which is what you have in your product. And— uh— Hydrolyzed Collagen contains 19 amino acids. And so, these are things like Glycine, Proline, Glutamic acid, Arginine, Alanine, and other essential amino acids and some non-essential amino acids. Maybe, before we get in to like deficiencies and Cortisol and stuff like that, maybe let’s just chat about amino acids and how important they for manufacturing neurotransmitters. I mean, you’ve got so many people with uh— mood issues, depression being number one leading cause of disability, I believe Anxiety. Actually, I just saw a report about that. I don’t know if you saw it. Anxiety is actually topping depression now as the leading cause of disability in the world by the Center
Dr. Justin Marchegiani: Yeah, and if you looked at the top ten essential amino acids, these are amino acids that your body cannot make. Arginine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, which is a precursor to Tyrosine. Uh— Threonine, Tryptophan, which is a precursor to 5-HTP, which is Serotonin, and then,
Evan Brand: Yeah. The interesting about Collagen, the only amino acid that’s essential that it does not contain is Tryptophan. And we use Tryptophan a lot supplementally and specially 5-Hydroxytryptophan, 5-HTP. Really, really helpful for people with mood issues, so anxiety and depression and all that, it makes sense. Why? I’ve had clients that say, “ Oh! I’ve been supplementing Collagen but I still have these mood issues.” So, you can still replenish other neurotransmitters but you’re not getting Tryptophan from Collagen, and— and interestingly a lot. So, if you do have mood issues, you may need Collagen plus 5-HTP. And you brought up the Vitamin C so I’ll take that a little bit further. In terms of testing, between Justin and I, both, we’ve probably looked at— I don’t know, maybe 3,000 or 4,000, who knows how many Organic acids test. This is a urine sample that we run on every new client. And you can actually measure Vitamin C on this urine sample. And I would say— and Justin tell me if your statistics are different— but I would say 80%, if not more, people have a deficiency or even no Vitamin C, works completely bottomed out. And as you just mentioned, you have to have Vitamin C as a cofactor to build Collagen. So if your skin looks like crap and your Vitamin C’s burned out, you’ve got some explanation on the— on the data.
Dr. Justin Marchegiani: Exactly. Now, Oxidation is important. Oxidation is when you lose electrons. So, if you put a rusty nail outside and it gets rusty, that’s Oxidation. The— The steel or the metal that makes up that nail losses electrons hence the rusting, or if you cut an apple in your house and you let the apple brown, that is Oxidation. Now, you can get some lemon juice, put it on it. The lemon juice is very high in Vitamin C, which then prevents the apple from browning. Why? Because it’s an antioxidant. It’s giving up electrons to stabilize the loss of electrons from the oxidation process. So that’s what we like. Vitamin C’s are really good adrenal support because a lot of adrenal stress creates Oxidation. Obviously, your adrenals use Vitamin C as a— is a kind of a cofactor for adrenal support to make some of the adrenal hormones from a nutritional perspective, kind of like the thyroid uses
Evan Brand: Yep. Well said. So there’s the answer. If you’ve been wondering all these years why when you look at a smoker, their skin looks so terrible and they look 20 years older than everybody around them
Dr. Justin Marchegiani: Hundred percent. One hundred percent. Now, regarding, you know, what the next steps are, right? You also talked about the gut. Now, I mentioned Glycine, which is one of the main amino acids in Collagen. It’s gonna be used for Glutathione, which is a powerful detoxifying antioxidant
Evan Brand: That’s amazing. So, you’re literally healing from the inside-out?
Dr. Justin Marchegiani: Correct.
Evan Brand: It doesn’t get [inaudible]
Dr. Justin Marchegiani: A hundred percent.
Evan Brand: Of course, we’re not doing just that. Like a leaky gut protocol, we’ve got several different custom formulations that we’re using, but it sounds like, based on what you’re saying here, we would definitely want to have Collagen in as a post-infection protocol for best results.
Dr. Justin Marchegiani: Correct. And there’s about— I mean, if you go look, there’s a lot of different like Collagen types. The most common ones are the I and III. Those are the ones that I use in my TruCollagen. The difference with my TruCollagen compared to most molt— most used Sulfuric acid is a
Evan Brand: That’s right.
Dr. Justin Marchegiani: And then again, we’re using the Type I and Type III. type I is skin, tendon, vasculature, organ, bone, and it makes up the major organic part of the bone. And then we have Type III, which is basically
Evan Brand: Yeah. [crosstalk] I’ve had an impulse in that one.
Dr. Justin Marchegiani: Yeah.
Evan Brand: It tastes pretty good.
Dr. Justin Marchegiani: yeah. I mean, the thing with Neocell, uh— a lot of it becomes from Tyson Poultry Farm chickens.
Evan Brand: [crosstalk] That sucks. So, I figured it wasn’t quality because— Put it this way, if it were quality like pastured animals, they would advertise it. “
Dr. Justin Marchegiani: Correct. So, it— it comes from the— the Neocell tends to come more from the Tyson Farm chickens, and number two, doesn’t blend as well. I mean, if you put it in your coffee or tea, is a noticeable flavor f— for me that disrupts the enjoyment of my coffee or tea. Uh— Where, if you use a really good proteolytic Collagen, it almost— it has no flavor at all and almost acts like a creamer. So, I love it ‘cause, one, that’s my creamer. And then, number two, it provides the extra amino acids. So, if I have someone who’s just not hungry at all, that doesn’t want to really eat much in the morning but they love their coffee or tea, well, we can at least put a scoop of Collagen in there. Get 12 to 15 grams of Collagen, and they at least get some good amino acids nutrients in their— in their gut. And also, it prov— provides support for the gut lining too, which is great.
Evan Brand: Yeah, well said.
Dr. Justin Marchegiani: And most people aren’t— they aren’t getting exposed. Even people that are Paleo, unless they’re doing bone broth, right— or doing bone marrow…
Evan Brand: Yeah.
Dr. Justin Marchegiani: …they’re just not getting exposed to it.
Evan Brand: Yeah. Well, when you were talking about that, I thought, “Man, this would be a perfect intervention if we were trying to get someone from a Vegan or a vegetarian template and try to get them over to
Dr. Justin Marchegiani: I have a lot of Vegans and vegetarians that— that I at least coerced them to
Evan Brand: Yeah.
Dr. Justin Marchegiani: Actually, I coerced them at doing at least a little bit of egg yolk if tolerated, and potentially, even a little bit of fish. So I may be able to kind of push them in that direction. But yeah, I mean, a lot of the Vegetarian protein sources, they aren’t rich in Sulfur amino acids and they tend to have a whole bunch of anti-nutrients bound up to them. So if
Evan Brand: Yup. I’m trying to think of those anything else
Dr. Justin Marchegiani: Uhmhm—
Evan Brand: …which is…
Dr. Justin Marchegiani: Yeah.
Evan Brand: …a cofactor for Collagen synthesis, but Cortisol in itself is gonna be catabolic. So, Cortisol can cause leaky gut issues…
Dr. Justin Marchegiani: Right.
Evan Brand: …because it can break down that gut barrier. But then let’s talk about that a bit more. You know, Cortisol can be affecting your skin, your gut lining. I mean, it’s pretty much the
Dr. Justin Marchegiani: One hundred percent. I think we made some valid points. And again, if you’re seeing hair loss, part of, I think, the mechanism for hair loss with a lot of these infections is number one you’re uh— you’re
Evan Brand: Well, what if Anemia is too? I mean that would be a whole nother podcast but Ferritin is a common thing we’ll see that’s low.
Dr. Justin Marchegiani: B vitamins, B12 for sure.
Evan Brand: Yeah. So there are Anemias and there are gut infections too. I mean, you know, with the— you mentioned, the thyroid Hashimoto’s— I mean, that could be a gut— a gut issue. That’s like H. pylori
Dr. Justin Marchegiani: Yeah. And I love Collagen because it provides the— the mechanism for skin, the cosmetic aesthetic asset. It also provides support on the gut aspect, and then it also provides support on the detox aspects. So, many, many sides of it. Think of Collagen as the scaffolding and all of the various osteobl— osteoblasts and fibroblasts that are growing around it. That’s the scaffolding that keeps it in place, right? Just like, you need scaffolding around the building so the builders can maneuver their way up the building to put all the rods and steel and glass and cement in place. Think of the Collagen as that scaffolding that provides that strong foundation for your— for the— for your other building block cells to do what they need to do.
Evan Brand: Makes you wonder, I mean, how often and how much Collagen our ancestors were getting. I mean, many people joke at us as humans eating muscle meat, and say that our ancestors— that was like the last thing that they went for. Have you heard talks about that? Like, the muscle meat was basically the— the least important part of the animal when they killed it?
Dr. Justin Marchegiani: There’s a Nova Documentary out there, and they talked about kind of the evolution of the human brain. And, basically, they have this kind of divergence of Homo
Evan Brand: I think they said it doubled in that timeframe.
Dr. Justin Marchegiani: Yep. And that’s kind of, you know, why we are where we’re at today. And that’s part of the reason why human species— like a lot of humans or not— a lot of other species, right— animal species. They developed super fast, right? They’re walking. They’re moving right away, right out of the gates. Humans don’t because all that energy is actually going
Evan Brand: [laughs] Exactly.
Dr. Justin Marchegiani: Because all the energy is going to brain growth, and that’s kind of where we’re at…
Evan Brand: Yeah.
Dr. Justin Marchegiani: …for the last couple of hundred thousand years.
Evan Brand: Yeah. Bison too. I think Bison literally like run with their moms on the first day of being born.
Dr. Justin Marchegiani: Yup. It’s because they don’t have uh— a frontal cortex that has taken hundreds of thousands, if not millions of years, in nutrients to get to where they’re at.
Evan Brand: Yeah, and people like, “Okay. what do I do now? Start eating bone marrow?” You could, but you could also just start doing these
Dr. Justin Marchegiani: Cool.
Evan Brand: And you’re gonna get the marrow from the— from the bones. I know Kettle & Fire, which is the company that— they sponsored my podcast for a while. I know they used all the bones and the marrow. People can actually get 20% off. I believe my link…
Dr. Justin Marchegiani: Right.
Evan Brand: I’ll do— I’ll double check it. I’ll just do a little plug here. I’ll make like two (2) dollars if you buy this broth using my discount, but you’ll save more than two dollars. Yeah. So, it’s evanbrand.com/broth, and if you use that link, you will get 20% off of bone broth. So, that’s pretty good. I drink it almost weekly. I don’t actually drink it by itself though, to be honest. I just mix it in with soups and recipes and stuff. If I’m doing like a stew…
Dr. Justin Marchegiani: Yeah.
Evan Brand: …
Dr. Justin Marchegiani: Yeah.
Evan Brand: I know that it’s much higher quality.
Dr. Justin Marchegiani: You get a lot more lunging Collagen peptides. Totally. That makes a lot of sense. [crosstalk] It’s great.
Evan Brand: Ann Louise Gittleman when I interviewed her for the Candida summit, she said that she had her team. I guess she has a team, kind of like Mercola, that goes and investigate stuff for her.
Dr. Justin Marchegiani: Uhmhm—
Evan Brand: And they tested a bunch of different uh— commercial, like organic bone broth companies. And she said also that Kettle & Fire was the only one that passed in terms of not being contaminated with heavy metals because, apparently, depending on where these animals are grazing, if the soil has heavy metals, and then obviously that’s uptake into the bone, like Lead. And then you make broth out of it, then you drink the broth, you could be giving yourself Lead. But she said that’s the only one that actually drinks. So, that was cool to hear.
Dr. Justin Marchegiani: Very cool. Excellent. Anything else you wanted to answer or address here before
Evan Brand: I think we covered it all. I don’t have the questions pulled up so I didn’t know if there were any there that you want to hit or not.
Dr. Justin Marchegiani: I think we’re good. I’ll just one li—
Evan Brand: [crosstalk] Make sure you put the link too. Make sure you put that link in this video for people. They’ll look it out. So, justinhealth.com/candida. Go register there for the event. I mean, we’ve literally already got 30,000 people registered and it’s not even until next month. So…
Dr. Justin Marchegiani: Love it.
Evan Brand: …if you— Imagine missing out on 30 of our podcasts together, that’s what it’s like if you miss out on this event.
Dr. Justin Marchegiani: Awesome, man. Anything else you want to add today?
Evan Brand: Not today. Take care. Reach out justinhealth.com for Justin if you want to consult. Evanbrand.com for me. We love to help you out. Take care.
Dr. Justin Marchegiani: Awesome, Evan. Have a go, man.
Evan Brand: Sure.
Dr. Justin Marchegiani: You take care.
Evan Brand: Bye.
Dr. Justin Marchegiani: Bye.
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REFERENCES:
evanbrand.com/broth
Ann Louise Gittleman in a Candida Summit interview