Gut health significantly affects mood, energy, and hair quality, often influenced by infections and environmental factors.
🦠 Gut infections can impact mood and energy levels.
💊 Conventional treatments often overlook underlying gut issues.
🏠 Family members may share similar gut infections, necessitating collective treatment.
📉 80-90% of patients exhibit gut issues affecting mood and energy.
🌾 Glyphosate exposure negatively impacts gut microbiota and overall health.
🧬 Nutrient absorption is crucial for hormone production and mental health.
🍏 Healthy eating habits in children shape their long-term health.
🌐 Interconnectedness of Gut Health: The gut microbiome is linked to mood and mental health. Poor gut health can lead to anxiety and depression, indicating a need for holistic approaches to treatment.
🔬 Limitations of Conventional Medicine: Conventional psychiatry often misses root causes, favoring symptom management over addressing gut dysfunctions that can impact mental health. This emphasizes the need for a more integrative approach.
👨👩👧👦 Family Health Dynamics: Gut infections can be shared within families, suggesting that treatment should involve the entire household to prevent reinfection and promote overall health.
📊 Prevalence of Gut Issues: A significant percentage of individuals seeking help have gut-related issues, highlighting the importance of functional testing to identify underlying problems.
🌱 Environmental Influences: Glyphosate and other environmental toxins can disrupt gut flora, emphasizing the urgency of dietary choices and awareness of food sources to improve gut health.
🍽️ Nutrition’s Role in Health: Proper nutrient intake is essential for hormone balance and mental health, underscoring the importance of a balanced diet rich in proteins and healthy fats.
👶 Foundational Nutrition for Children: Early dietary choices are critical for children’s long-term health, as good nutrition sets the stage for better health outcomes in adulthood.
Dr. Justin Marchegiani: And we are live. It's Dr. J here in the house with Evan Brand. Evan, how we doing my friend? Hey man, doing great. Excellent. We chatting in the pre interview, pre podcast, talking about the impacts of gut on energy, mood, and hair. Again, when we create these topics, we tend to Look at what our patients are telling us.
Dr. Justin Marchegiani: What are some of the big complaints that are coming in? And then we try to use that information and put it out there. One, because it's top of our minds. But two, we want to provide extra value for our patients and listeners. Really excited to dive into this topic.
Evan Brand: Yeah, when I had H. pylori, I had major mood issues and I had no idea that there's actually published literature on it.
Evan Brand: So if you just go to PubMed, you can put in H. pylori mood or H. pylori anxiety, H. pylori depression, and you'll find several papers on this idea of mood issues being driven from literature. Just this one bacteria. Now, when you and I run functional lab testing like a GI map, sometimes we'll see 5 to 10 different infections.
Evan Brand: So Klebsiella and many others can be there, not only affecting the immune system, but also affecting your brain. And if you run to your psychologist who then refers you to your psychiatrist for anxiety, unfortunately, your psychiatrist is not gonna run a stool test before they go and prescribe an antidepressant or an anti anxiety medication.
Evan Brand: Dr. Justin Marchegiani
Dr. Justin Marchegiani: 100%. Most of the time when you go to a psychiatrist, they are really just using a band aid approach that is robbing from tomorrow to pay for today, right? They're robbing Peter to pay Paul. So if you look at someone that's going to their psychiatrist for OCD, they're going to just provide basically either a pharmaceutical stimulant, like a crystal meth, version, whether it's like an Adderall or like a Vyvanse or some kind of a precursor that gets converted into Adderall that just puts your body into a constant sympathetic state.
Dr. Justin Marchegiani: When we're in a constant sympathetic state, it's hard for us to go parasympathetic and heal and recover and sleep well and wind down and relax. Also, what is being in a chronic sympathetic state due to your hormones? It's going to overproduce cortisol. Or decrease your DHEA, decrease your sex hormones over time, because that chronic fight or flight response has a depletion of your hormones over time.
Dr. Justin Marchegiani: And so this is what, let's say on the OCD side, what's done, or on the, let's say the mood side it's gonna be your SSRIs, it's gonna be your SNRIs, that works on serotonin, dopamine, adrenaline, or it's gonna be your GABA, your benzodiazine, that'll work more in GABA as well. And so these medications, Especially the benzos are really hard to get off of too.
Dr. Justin Marchegiani: They can be very addicting. So when we look at these medications, we want to say, hey, what mechanisms upstream are being impacted and what diet, lifestyle, and supplement changes we can do, what lab changes that will functionally look at what's happening, can we do?
Evan Brand: Evan Brand Yeah, said. And then one thing we gotta point out is the family impact, meaning the husband, the wife, the children could all have these similar infections.
Evan Brand: So it's very important for the females listening because that's the majority of our practice are females because the men just don't want to admit something's wrong. These women, they could likely be getting re infected from their spouse. So if you're finding that you're on a protocol, maybe you've worked with us, we put you on a gut protocol, you're doing really well.
Evan Brand: Maybe you backtrack two, three months in and you're confused about why am I losing more hair? Why all of a sudden am I more anxious? More depressed? Why have I hit this either a roadblock or maybe even a downturn? A lot of times if we can get the spouse on board or the children, we'll test them and then boom, we'll see the similar gut infections.
Evan Brand: So we wanna make sure you all understand that you often cannot just treat you and your little bubble. If it's a whole household with people suffering, we've got to get the whole household involved. Same thing with a friend from school. Her daughter had gut issues, then the son had issues as well, then the mom and the dad both had gut issues.
Evan Brand: And I said, look, all four of y'all need to be on this protocol. And now they're actually making progress for the first time.
Dr. Justin Marchegiani: Yeah, gut infections can be a big bottleneck because number one, it's throwing off your microbiome. It's decreasing the beneficial bacteria in your gut that play a major role with your immune system.
Dr. Justin Marchegiani: Remember, 80 percent of all your immune cells are in the gut. And so if you have an imbalance in these immune cells because of chronic stress and inflammation, you'll have decreased immune function. If you have bad bacteria that can also overproduce histamine, so now your histamine bucket's full and now you may be more sensitive to histamine foods, histamine in the environment from allergens and dander, maybe even mold you add some mold to it, now your histamine bucket's overflowing, and then of course the bottleneck of all these beneficial bacteria producing endogenous nutrients, they produce B vitamins, they produce K2, they produce a lot of important nutrients for cellular function and for immune function.
Dr. Justin Marchegiani: And then of course, we need to take in these nutrients via our diet, via protein fats, and we have to be able to break them down. So we get them exogenously from the environment in, and then endogenously through good healthy microbiome balance, and then we produce them that way too.
Evan Brand: Evan Brand Now, when we talk about these things, people often ask, how common is this?
Evan Brand: How common is dysbiosis? So maybe we could give people a couple numbers. You and I've run at least 5, 000 labs or more between us both. How often would you say either maybe you could do it out of 10 people or out of a hundred people? How often would you say we're seeing a dysbiotic flora that's impacting mood, skin?
Evan Brand: immunity, hair, energy.
Dr. Justin Marchegiani: We have a skewed population because people are coming in that have already gone to see their doctors and they're not getting the help and of course, people are coming in. What percent of people that we see come in have a gut issue? I'd say 80 90 percent of the time there's a gut issue in their top 3 5 complaints.
Dr. Justin Marchegiani: Yeah. And conventional medicine, they just get labeled with IBS and then it's just gonna be antispasmodic, laxative, acid blocker, Maybe a steroid, maybe, antibiotic, right? They're just maybe a prokinetic. They're just kind of band aid treating the symptoms, not really getting to the root underlying cause.
Dr. Justin Marchegiani: And we're really the perfect candidate for these people. Now, the question begs, why? I think it's a combination of crummy diets. Processed sugars, processed grains. I think there's glyphosate residue in a lot of this and glyphosate was originally patented as antibiotic. And so we know it has negative impacts on our microbiome over prescribing antibiotics as a big one, processed sugar.
Dr. Justin Marchegiani: And I think chronic stress lowers our stomach acid, lowers our enzymes, makes it harder to break down the food. And so then our gut has a harder Evan Brand
Evan Brand: I'm gonna pull up a glyphosate usage map and I know that there's one from 2011. I'm gonna see if there's a newer one. Yeah, it does look like the USGS did put out a 2019.
Evan Brand: Let me share this with you real quick because I just want people to understand that your environment has a massive impact on your gut and if you could pull that up because this is from. the USGS. So this is a really good study. And what you're looking at here is the United States estimated use on agricultural land and pounds per square mile.
Evan Brand: And you'll see virtually the entire Midwest all the way down the Mississippi. There is over 114 pounds of glyphosate per square mile. This is massive. And so if you were to plot all the cases of cancer, all the cases of skin issues, dermatitis, eczema, all the Children that have messed up guts. I'll tell you, literally, if you and I took all of our clients and we overlaid them and their address and their zip code with this map, a lot of it would be Match up perfectly.
Evan Brand: Now we've seen our fair share of people in Utah and Arizona and Nevada and other places globally, where maybe there's not this problem, but if you just really look how much of the U S is contaminated, it's pretty shocking. And then if you look here, looking at since 1992, ramping up to 2018, this has gone up.
Evan Brand: Literally 10X in terms of the usage and that's millions of pounds here. So we're above 250 million pounds across the different crops, primarily corn, soybean make up the majority. And then you've also got your cotton, alfalfa, your pastures. So we can't ignore this. Like you and I talk about this, like it's some like little piece to the puzzle.
Evan Brand: But when you look at the scale. Of this it's mind blowing and this is something that we can detox. So it's not all doom and gloom You and I have some really good experience with adding in specific probiotics to help with this We have specific binders and different nutrients that we use We have several different detox products that help with this and we've run testing on the urine So that's one thing we can do if you have a gut skin a mood issue fatigue hair loss When we do our organic acids testing for a little extra money, we can add on a chemical profile You We can actually add on glyphosate.
Evan Brand: We can measure this in you. And I've really found a person with zero glyphosate, even someone that eats 100 percent organic. Some of it is from them living too close to agriculture. Some of it is just the exposure. Unfortunately, even rainwater samples have been found to have this. So I think There's no hiding from it.
Evan Brand: We just have to make sure we're constantly working on improving our microbiome to be able to neutralize, to bind it, to excrete it, to convert it into something less dangerous. Maybe the glutathione is helping. It's not just one mechanism. It's probably five or six mechanisms we're doing to try to fix this.
Evan Brand: Dr. Justin Marchegiani
Dr. Justin Marchegiani: Yeah, and there are studies here, looking at, let's say glyphosate impacting the gut microbiota, right? So they call it, there's an enzyme called the EPSPS enzyme. A lot of in vitro studies shows that it negatively impacts the gut microbiome, and so we know that's a mechanism.
Dr. Justin Marchegiani: It's powerful. So the easiest thing you can do outta the gate, try to be organic or at least, eat the clean 15, avoid the dirty dozen. This will have the least amount of pesticide residue on those foods, and you try to save some money. Try to do frozen on the vegetables on the organic side. Those are some good kind of starting points that you can try to get that low down.
Dr. Justin Marchegiani: It's not a zero sum game, but the less you do, the better it is.
Evan Brand: And your kids, they're smaller. So this is more important for them. So honestly, if it's a choice of you sending your kid to school with conventional, which should be called chemical, if it's you sending them with conventional strawberries for their school lunch, their summer camp lunch or organic, like if you can't do the organic in terms of the price, I just looked the other day, it was like a dollar difference, maybe 1, 50 difference to get the organic.
Evan Brand: If you can't afford that, Don't even do the strawberries, just do a pineapple instead. I saw even at Walmart right now, you could get a pineapple from Costa Rica that's on the clean 15 for around 2, 2. 25. You can get a whole pineapple that you can cut fresh. Dr. Justin
Dr. Justin Marchegiani: Marchegiani Yeah, you can go to Costco right now, you can get pretty good deals on Costco.
Dr. Justin Marchegiani: It's it's just not so much. You can buy things in bulk. You can get a big thing of organic blueberries for five, six bucks, huge, almost a pound worth of blueberries. But look at this right here. This was the study I was looking at here just so you guys can see. This is a study looking at low dose glyphosate exposure alters gut microbiota composition and modulates gut homeostasis, June 2023, environmental toxicology and pharmacology.
Dr. Justin Marchegiani: I talked about the EPS pathway right here, and look at one study shows that the common bacteria, Lactobacillus and Bifida were the most susceptible to the glyphosate exposure.
Evan Brand: Evan Brand And that matches up with what you and I see on the Marchegiani Oh yeah. Evan Brand We have a whole section there where we look at what are called Keystone or commensal bacteria.
Evan Brand: These are the good guys, and we will always see these two low. These are probably the lowest ones we're gonna see. And then Acromantia, I don't know if you've paid attention to that, but I see low all the time since I see a
Dr. Justin Marchegiani: lot. Dr. Justin Marchegiani And there's a lot of good benefits for acromantia, whether it's gut permeability, producing mucus just reducing inflammation.
Dr. Justin Marchegiani: So there's a lot of good things that I see acromantia, in the literature popping up for and benefiting. What are you seeing acromantia helping? Evan Brand
Evan Brand: I'm seeing it help with people's skin issues, which is odd. I really just started playing with it. As just a few years ago, we didn't have acromantia on the GI map stool test.
Evan Brand: It's a relatively new addition to the test panel. And so now that I'm seeing it, I feel obligated to help people supplement with it. I'll chat with you about some cool developments off air. I've got a couple of cool things that you and I could play with some Acromantia multistrains, like with some extra probiotics, but I think that it's something that people should look at and if you have not had a stool test, reach out to us, let us help you get one because this is really one of the key ways that we're gonna prevent you from chronic disease because these bacteria, these issues, we're talking about with glyphosate exposure over time, how these overgrowth bacteria develop is because your good guys are too low.
Evan Brand: So what you're showing in that study there is saying, hey, the good guys are down, so now the good guys move in. Your clostridia, your klebsiella, these other infections, and that's gonna potentially drive it. Okay. Autoimmune, irritable bowel diseases, and all sorts of other problems. You start messing with glucuronidation.
Evan Brand: Now your risk of colon cancer goes way up. So when you see your friends, your family just falling apart, really. A lot of this is happening right here in the gut.
Dr. Justin Marchegiani: A hundred percent. Couple little things here. I pulled up doing a little research on Akkermansia a couple days ago, but gut health integrity, a very important.
Dr. Justin Marchegiani: Acromansia plays a role, like I mentioned in that mucus layer, which is protective against pathogens. Remember, a lot of these bugs have to gain access to those crypts to the endothelial lining or H. pylori to dig in and burrow in. And so having a good mucus layer does provide protection.
Dr. Justin Marchegiani: Obviously, nutrients, nutrient absorption is really important. Strengthening that gut barrier does help improve nutrient absorption and does make things like leaky gut less dangerous. possible. And then metabolic issues. We see that acromantia has a major effect on the metabolism and less acromantia does correlate to more insulin resistance and more body fats and more metabolic syndrome.
Dr. Justin Marchegiani: That's important. And of course, talked about 80 percent of the immune system is in the gut. So Echromancy has been linked to modulating the immune system, which does help lower inflammation and we see less things like Inflammable Bowel Disease or IBS and allergens in general. Evan
Evan Brand: Brand Yeah. That's right.
Evan Brand: I guess it makes sense now what I'm seeing with skin. People are saying, Hey, eczema is better now. Some people are putting it into their kid's smoothies and they're saying, Hey, my kid's skin's better. I'm like, okay, cool. Like I'll take it. Sounds good to me. Dr. Justin Marchegiani No, that makes sense. I like that.
Evan Brand: Evan Brand Yeah. Dr. Justin Marchegiani
Dr. Justin Marchegiani: So we talked about mood out of the gate. So we know a lot of our neurotransmitters come from protein. And so these are all going to be our peptides. These are going to be our building blocks for serotonin, for dopamine. Dopamine's a building block for adrenaline, norepinephrine.
Dr. Justin Marchegiani: We need sulfur amino acids as well to help with the transulfation pathways and a lot of the conversion of these neurotransmitters. GABA, gamma amino, right? Amino butyric acid. So that's the amino acid building block there. And melatonin is going to come from serotonin. So there's another amino acid building block there.
Dr. Justin Marchegiani: And so these play a major role with mood, focus, energy, sleep, and circadian rhythm, right? Melatonin goes up and cortisol goes down. So we have this inverse relationship between melatonin up and serotonin down. Cortisol throughout the day, at night it comes down, so melatonin up, cortisol down. So melatonin is a very powerful antioxidant, does help sleep.
Dr. Justin Marchegiani: And then of course, our hormones. Most of our hormones are gonna be cholesterol based. We have two major peptide hormones, that means protein based, that's gonna be your insulin and growth hormone, but then rest is typically gonna be steroid based, your cortisol, steroid based. Your estrogen, progesterone, testosterone are typically all gonna be cholesterol steroid based.
Dr. Justin Marchegiani: And so we need to absorb our proteins and our fats. Dr. Justin Marchegiani. And our healthy animal products. And if we don't have good gut function, these nutrients, these building blocks will not be able to adequately And you say, oh we're
Evan Brand: Biased practitioners because the people have already exhausted the conventional doctors before they reach out to us.
Evan Brand: But man, some of the people that you and I see look really good, like their face, their skin, they're fit people that we're working with. In some cases, these are athletes. Dr. Justin Marchegiani. And so they even have issues on paper. So then you look at your average American sitting on the beach, they're a hundred pounds overweight, they're lathering themselves in toxic sunscreen.
Evan Brand: They're eating Cheetos and they're feeding their kids goldfish. So I think even in our population the issues you're saying here, probably in the 80 to 90 percent with gut issues. I think the average person, the average American who is still asleep to all these different things, it's 99%.
Evan Brand: If we go and test like a hundred strangers that look the way I see people look, it's 98 out of a hundred is gonna have a problem.
Dr. Justin Marchegiani: Yeah, it's just, it's very simple, right? When you understand physiology, it's if you're building a home and you know you need so much, lumber for the framing of the home or so much, tons of concrete for the foundation or so much piping or drywall to put up that property.
Dr. Justin Marchegiani: If you don't deliver enough, there's going to be a supply issue. Now it's different because just because you put it there, there's digestion that requires in your body to, you have to absorb it and assimilate it. And then what if you're stressed, you may actually burn it. So it's not like a one to one, Hey, I put one gram of protein.
Dr. Justin Marchegiani: And that means my body has one gram to work with. No, it may be cut in half once you add in the thermogenic effect of food and absorption and assimilation. And maybe you have motility problems. Maybe you're pooping some out. You may not get all of it, right? So you may say, Hey, I'm putting enough raw material to the construction site.
Dr. Justin Marchegiani: For the framing of the home, but maybe with stress and with absorption, there's less and these not
Evan Brand: only do they affect your energy, your mood, we're talking about that in your hair, but they also affect your weight in terms of what it can do to your make you fat. So we talked about glucuronidation.
Evan Brand: We've talked about malabsorption. You mentioned issues with protein and fat digestion. Just look here in the trends among children and adolescents. This is age 2 to age 19 in the U. S. We're looking at data from starting out in 1963. Now, the latest study here looks like it was up to 2018, and you can see we've 4x'ed it.
Evan Brand: It was around 5 percent of kids had obesity, and now we're up to above 20%. It looks like in teenagers and this is six years old. This data six years old.
Dr. Justin Marchegiani: Yeah, I don't understand it. I get it. I see it as a parent. It's it's very simple for me. My kids only have what I put in the fridge.
Dr. Justin Marchegiani: And so we just keep all the crap out. Or if we have treats, we try to buy the low sugar, the unreal, dark chocolate coconut, or we get the stevia sweetened lilies, peanut butter cups, like we try to choose treats that are going to be, low sugar, good fats. And we make our kids eat their proteins and fats first and do well, having them eat some veggies and some fruit.
Dr. Justin Marchegiani: But, kids can't drive. They don't have, they don't have a car. They don't have their own money yet to buy stuff. And really, the parents have to do a better job creating a good environment at home where all you have is
Evan Brand: and I agree with that. And, Even like Walmart, you can get a three pack if you don't have a Costco membership or maybe there's no Costco around you, at least if you have a Walmart.
Evan Brand: I've seen them doing organic grass fed meat. You could do a three pack of ground beef and ends up like five, six bucks a pound. Look at this. Dr. Justin
Dr. Justin Marchegiani: Marchegiani Oh my gosh. And with my kids too. We tell them. It's like you're eating your protein and your fat first. The other day, we gave my kids his apples and some Siete chips.
Dr. Justin Marchegiani: He ate it all and then he's I don't, I'm not hungry enough to have my, grass fed sausage. He's now we. Pull all the carbs out and we do the protein first, then we get the carbs after. So this is the
Evan Brand: age adjusted percentage of US adults with overweight, obesity, and severe obesity.
Evan Brand: So if you take all these numbers here, this percentage of the population in the US, you take the 30. 7 that are overweight men and women, you take the obesity, which is 42. 4. Okay, it does say it includes the severe. You're looking at well over 70 percent of the population is either overweight or obese at this point.
Evan Brand: It's if you see a fit person, they're like a unicorn almost. Dr. Justin
Dr. Justin Marchegiani: Marchegiani Yeah, and I just tell parents, start, give your kids what they need, not what they want. Don't be your kid's friend and give them what they need to be healthy, right? Start there. It's really important, right?
Dr. Justin Marchegiani: Environments, everything. Start your day with good healthy proteins, good fats. Start your day with lower sugar fruit or carbs that are gonna be, starchy base, sweet potato, maybe some white potato, but keep it good clean whole food stuff. You'll be in a much better place for sure.
Dr. Justin Marchegiani: Evan Brand And this can be
Evan Brand: driven by the gut problems cause the gut problems are gonna drive more sugar cravings and these kids are not even gonna have the palate for the meat because they're so altered by the candida that's driving the sugar cravings and so they just want the skittles and so it's not necessarily your fault.
Evan Brand: It's just that you dug yourself in a hole and we can help you out of that hole. And some of that is by using this data not only as a clinical tool to help guide us and protocol creation, but also a compliance tool to say, Hey, look, there is this issue driving this craving leading to that food choice, leading to this issue with your mood.
Evan Brand: And so if we can just work backwards from the lab, we can help you get better. So I just encourage people to reach out to us and if you've not had a workup, let us do a workup. It's cheaper than a brand new iPhone. You can get some really good functional medicine lab data.
Dr. Justin Marchegiani: A hundred percent. Kids today, they, everything has to taste amazing or great or it's I don't want it.
Dr. Justin Marchegiani: It's no, it's okay. You can eat some vegetables. If you don't love it, it's okay. Because over time, I'm going to eventually get your palate dialed in where you want it. Kids have to get more comfortable doing things they're uncomfortable with. Like with my four and six year old, I put him in my cold plunge for 20 or 30 seconds.
Dr. Justin Marchegiani: I'm like, it's okay, we're going to do something that's uncomfortable. It's good to feel uncomfortable, get through it, and that character that you get from I did this hard thing and I overcame it and here I am, it's okay, right? And so getting kids Whether it's food, whether it's cold, whether it's chores, whatever.
Dr. Justin Marchegiani: It's okay. You ever seen that
Evan Brand: meme? Those like a meme or some kind of old picture of like kids in rush out in the winter, like in their diaper, like diesel two year olds are just out and they're fine.
Dr. Justin Marchegiani: Yeah. Yeah. You've seen the meme where it's like 1950s kids playing at the playground and they're like on jungle jams that are like 30 feet in the air.
Dr. Justin Marchegiani: It's Oh my gosh. Anyone falls, they're breaking a neck. Yeah, so I tell my kids all the time I don't want to take my supplements or my NAC or my curcumin, it's it's okay you don't have to, but you're gonna, right? You don't have to like it, but you're gonna do it, it's okay.
Dr. Justin Marchegiani: Evan Brand
Evan Brand: Well, the good news is, too, like when you embrace these functional medicine strategies, if you do have children, you're listening, you're watching, or you wanna have children, All the stuff we're talking about today, by the way, does improve fertility, does improve sperm quality, sperm motility, improves fertility in women as well, optimizing your gut, is improving your digestion, therefore improving your nutrient absorption and your ability to create a baby and then therefore nourish that baby throughout the pregnancy.
Evan Brand: But as you get your kids to feel better, they're actually gonna start begging for this stuff. I know you and I both, our kids will come and say now, like this morning, my, my middle kid. She's daddy I was jumping weird and hopping around on one foot. I'm like, okay, would you like this pain and inflammation supplement?
Evan Brand: Yes, so we dose her up and by the time we get to the summer camp today. She's like daddy my feet already feel better I'm like great. So now they're making the connection. I had this complaint because I was being silly And then I feel better. And so that, that's the really rewarding thing about this.
Evan Brand: Dr. Justin Marchegiani
Dr. Justin Marchegiani: Oh, yeah. Yeah, we let my son Hudson the other day have a little bit of ice cream, a little bit of dairy every now and then. 90 percent of the time it's not there. He's dad, I think I need some enzymes and some probiotics. I said, I think you do. We got him lined up.
Dr. Justin Marchegiani: We got him lined up. But yeah, we try to do good options. You get your kids healthier, and they can, have a little bit of stuff here or there. Not a big deal, but also to like we're looking at the pottinger cats experiment coming alive, right? The pottinger cats experiment is dr pottinger in the fifties to cats and took them away from their natural diet.
Dr. Justin Marchegiani: And within, I think, three generations, the cats lost the ability to reproduce. And so there's a direct correlation with poor nutrition and that nutritional debt gets passed down to the next generation to the next generation. And so you wonder why infertility is at the highest rate ever. Of course we have xenoestrogens in the plastics pesticides.
Dr. Justin Marchegiani: Dr. Justin
Evan Brand: Marchegiani Yeah, I
Dr. Justin Marchegiani: think we're hitting all the big stuff and then of course, like the gray hair component is. All these things create inflammation, create oxidative stress, the nutrients, the selenium, the zinc, the important amino acids, the cysteine, all these things that help neutralize the hydrogen peroxide at the follicle level that bleaches the melanin in the hair.
Dr. Justin Marchegiani: All these things are going to impact hair quality as well as the grayness due to the oxidative stress. Of course, as you get older, there's that natural genetic oxidation that will happen and you will get a little bit gray, but you can definitely starve it off and hit the gas pedal or hit the brake pedal and slow it down versus hitting the gas and accelerating and causing more gray you about
Evan Brand: this, who he was probably early 50s and he was going through a divorce and I hadn't seen him in a year.
Evan Brand: He was a hunting buddy, so I didn't see him until hunting season came around and he went from fully brown to fully gray, like in one season. I'm like, dude, but here's the weird thing. I thought, maybe I'm crazy, maybe he died and didn't tell me, I thought that process was permanent, but after the divorce and everything got settled, I saw him again the next season, and he had actually had some more brown back in his hair.
Evan Brand: So it seemed like it did kinda go back.
Dr. Justin Marchegiani: Extreme cortisol from something like that could definitely do it. Poor nutrition. Getting things like cysteine up, which does help with that catalase enzyme that does neutralize hydrogen peroxide. Getting zinc and selenium up does help with the hydrogen peroxide.
Dr. Justin Marchegiani: which does bleach the hair. Also getting things like NMR, nicotinamide riboside chloride, or niagen for instance, does help with the oxidative stress. Curcumin, resveratrol, if there's a DHT component, due to baldness, SA Palmetto can be very helpful, decreases that DHC, that AR enzyme as well.
Dr. Justin Marchegiani: So lots of different things. But of course this is all keratin, right? This is protein. So if you have bottlenecks in the gut with protein, that could easily happen and you can get a tele intelligent effluvium hair shedding where that. diffuse sitting across the entire hair with low protein. Evan Brand Yeah, give us your comments.
Evan Brand: Give us some feedback. If you like the hair talk, we could do a whole another show. I think we've already done a hair law show but I mean we're happy to do more. So put your comments if you're on the Dr. Justin Justin Health YouTube page. Put your comments there as well. That way we can refer back and we're happy to get some feedback.
Evan Brand: know, tweak the content for you guys. And if you need to reach out clinically, Justin Health, there's consults available worldwide and we have international distributors so we can pretty much work in every corner of the globe. So justinhealth. com for Dr. J. I'm at evanbrand. com. You can reach out to us.
Evan Brand: We're really happy to help you guys. We love doing this stuff. We're so passionate about building these protocols to help you transform your life, get your energy, your libido, your mood, your gut, everything, your skin, as best as it possibly can, even if 5, 10, 15 practitioners before have failed you, we're likely gonna uncover something you've never even thought about.
Evan Brand: And that's why we love doing this.
Dr. Justin Marchegiani: Dr. Justin Marchegiani I love it. I think it's so important. I'll be live today with another live podcast, so if you guys wanna check in, take a look at that. But yeah, EvanBrand. com and JustinHealth. com, we're here to help. Put your comments down below. I'm checking them every night, so I'd love to be able to respond.
Dr. Justin Marchegiani: Evan Brand Alright, sounds like you got a catfight
Evan Brand: or something to tend to, so we'll let you go.
Dr. Justin Marchegiani: I got one cat running there and my dog butters like seeing my cat and mama cat outside. So yeah. All right, man. We'll look forward to seeing you again soon. All right.
Evan Brand: Take care. Bye. Bye.
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