Are You Sensitive to Antinutrients (Salicylates and Oxalates) in Plant Food? | Podcast #336

Food intolerance are very common problems that can be difficult to diagnose. In this video, Dr. J and Evan explain the causes and symptoms of salicylate oxalates sensitivity. Salicylates are compounds that you can find in foods, medications, and other products that can cause adverse reactions in intolerant ones. An intolerrance to these compounds is linked with a wide variety of symptoms, making it hard to identify. The most common symptoms involve the respiratory system. However, the skin and intestinal tract may also be affected.

Oxalates are often known as an anti-nutrient, as they tend to bind up some crucial nutrients in foods, which stops them from being fully absorbed. Intolerrance occurs in your body when the oxalates themselves are not detoxified from the body, allowing them to build up in the tissues. A low-oxalate diet is commonly advised for joint conditions including arthritis and gout and children on the spectrum.

Dr. Justin Marchegiani

Dr. Justin Marchegiani

In this episode, we cover:

0:09     What are Antinutrients

4:15     Diet Templates

12:51   Carnivore based Diets

17:06   Root Causes on Inflammation

21:21   AIP

27:24   Magnesium Benefits

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Dr. Justin Marchegiani: And we are live. It’s not the J here in the house with Evan Brand. Today we are going to be chatting about anti nutrients in food. Anti nutrients are one of these controversial topics because a lot of plants have a lot of nutrients in them, right blueberries, right? raspberries, a lot of these really good like spinach, spinach, things like that, right? But they have some of these things known as anti nutrients, whether it’s oxalates, or phytates, or salicylates, right, these are kind of under the overall umbrella of phenol, right polyphenols. And for people that are sensitive, and have gut issues and immune stress, this may be something that actually causes more harm than good. If you have good gut health, the nutrients in those food are going to be obviously beneficial. So it just depends kind of where you sit in that scale. But today, we’re gonna dive in and break it down. Evan, how are we doing today, man?

Evan Brand: I’m doing really well. And I’ll tell a quick story. And then we’ll dive into this thing. So I noticed that my daughter was complaining after I gave her blueberries we do some organic wild blueberries, I may give those to her just on a plate just as a snack or I may just put those in a smoothie and we’ll do like some grass fed beef peptides. And then I noticed she said, Daddy, my tummy hurts. And I thought, huh, that’s interesting. And I correlated it to the blueberries. And upon researching into salicylates, the quote, very high category of salicylate foods would be blueberries, cherries, blackberries, apricots, orange, pineapple, raisin, strawberries, tangerines, and then lower than that, like high but not very high. You got apples, you have avocados, you have Mandarin, nectarine, passion fruit, peach, and then like your very, very low. salicylates would be like pear or banana, or Papa, which we have here. A lot of pawpaw trees in Kentucky. That’s kind of a native fruit. They’re kind of weird. But some people really, really like them. That’s what Yeah, yeah, they’re cool. They’re cool tree. But it’s a pretty short tree, and they’ve got a pawpaw fruit on it. It’s kind of interesting thing. But anyhow. So long story short, I’ve determined there’s definitely a trigger. And totally, we’ve talked about this before, with like paleo and more carnivore type diets. The idea is that if you just go more meat based animal based diet, you’re really pulling a lot of these anti nutrients out. And that’s why people feel better. But that still doesn’t get to the root cause of why you’re having the intolerance in the first place. So I think that’s important, you and I eventually get to that, I think it’s good. We’re gonna give some backstory and education. But I think it’s important to point out early on here that if you have a sensitivity to these foods, it’s not to mean that you can’t or shouldn’t eat those foods. It’s you got to figure out why are you so sensitive, and there are some big root causes we’re going to dive into?

Dr. Justin Marchegiani: Exactly. Now. I just I like to, I like to have a lot of common sense. Try to be like the mayor of Rio Ville here, right? So if you’re coming in, and you’re listening to this podcast, and you’re on like a standard American diets, so to speak, don’t worry about it. We’re just trying to get you to eat whole foods that are nutrient dense, anti inflammatory, and low toxin like that’s our first step out of the gates. This is all window dressing, right? So once you’ve been doing the right diet, doing the right thing, and you’re still having some gut issues, some immune issues, this is kind of where we’re going to come in and fine tune things after the fact. So if you’re coming in, and you’re like, Man, this is like killing me. I can’t eat blueberries, like everyone’s telling me blueberries are healthy, what the heck, right? I get it, that can be really overwhelming. So don’t worry about that out of the gates just really get a good nutrient dense anti inflammatory, low toxin. Get your carbs and check out of the gate. Start with that before you do any thing. Else. Any comments on that evidence?

Evan Brand: Yeah, well said. And if you’re coming in, and you’re new to the diet game, nutrition game, really just organic as much as possible. And paleo is going to be a great starting place for you. We don’t want you to be afraid of certain foods or certain food categories. This is more of like a nutrition 301 nutrition 401 level courses is like a college level nutrition course. Because if you come in, and now like you said, You’re afraid of blueberries, you’re going to be too stressed. So these are this is more designed for people that are maybe working with us clinically, or they’re working with another, you know, functional medicine practitioner, and they’re maybe still teasing apart some things that are irritating them. This is going to be for you guys. 

Dr. Justin Marchegiani: Exactly. So 90% of people are going to go on some kind of a paleo or autoimmune template, and that’s going to be enough, right? Others are going to have to do things like cooking the food can decrease some of these anti nutrients, it can decrease some of the oxalates some of the salicylates some of the fight dates, right? We know things like knots are very high in fight dates. For instance, you know, soaking those can be helpful. Obviously, going on an autoimmune diet, we’re going to restrict knots, right. So kind of going autoimmune. We’re going to be restricting a lot of these foods just in general, going paleo you kind of restrict a lot of them because there’s a lot of anti nutrients in grains. So grains are going to be a big anti nutrient one beans and lentils are going to be a big anti nutrient one. So just by kind of getting on board of a paleo template where we’re cutting out grains, legumes and dairy. Maybe we have some meats and Vegetables and Fruits and safe starches, safe searches or grain free searches. And maybe some fats, including some dairy, that’s great, we may have to go one level up where we restrict even butter and dairy, and of course, even nuts and seeds, right. And then of course, after that, we may have to be doing extra things like restricting fodmaps, because of the fermentable carbohydrates that are in some of these healthy foods like broccoli and brussel sprouts. And again, the reason why these foods have to be restricted is not because the foods themselves are bad, but because it’s more of the gut, your micro biomes interaction with those foods that are the problem. So if we have bacterial overgrowth, right, and you’re interacting with these foods, then you’re going to be creating lots of gases in your intestinal tract like methane and hydrogen that are going to throw off your your motility that are going to make it harder to digest your food to absorb your food to break down protein to break down fat. So it can really throw off a lot of these different things. So I always tell patients out of the gate, the goal is to eat the right foods that allow you to feel as good as possible, not add more stress on your body. And ideally, your body can break them down because healthy foods not broken down. They ferment they are instead of phi. They putrefy and they basically rot inside your tummy and that’s not good. So we have to have those kind of things lined up and some people with autoimmune stuff, we have to go and restrict the salicylates or the oxalates. And again, for instance, I see a lot of chronic eczema patients. Sometimes we really have to go low salicylates. On XM. I see that a lot with eczema. salicylates are a big one. So I have a handout that I use a patient’s pull it up here in a second, where we kind of work on restricting a lot of the salicylates and potentially some of the oxalates. If we see a lot of vulvodynia, like just random, like joint pain, tissue pain, a lot of times those oxalate crystals can get into that tissue and really create inflammation. And we can assess that with a specific organic acid test and Opus oxalates there. And we can also look at a lot of the underlying skin stuff that we see there’s a lot of chronic eczema that’s not getting better with an autoimmune diet, we may look at going low solicited as well. So there’s a lot of different tools we have in our tool bag. But all of it comes back to the gut, we have to work on the six hours and moving the bad foods, we may have to go deeper, like I mentioned with the other foods with cooking the foods really well. Nothing wrong, really working on enzymes and acids and bile support really working on gut healing support, anti inflammatory support, that’s gonna be the foundation before we go in and address gut killing, because gut killing can be stressful on the gut, and you have to have those first two to three hours lined up to mitigate damage.

Evan Brand: Yeah, and you brought up the organic acids test we’ve seen to clinically the correlation between candida overgrowth and oxalates being high. So interestingly enough, when we come in and we use a protocol, like you’re mentioning, will come in and address gut infections, whether it’s parasites, worms, H. pylori, fungal overgrowth, we’ll see those oxalate markers come down quite a bit. So in a lot of cases where people are sensitive to these food groups, finding the gut infections, and then fixing those gut infections can reduce the sensitivity. So this is the problem I have with people that are just strictly nutritionist is they can avoid going deep enough. And you could just keep tweaking the diet and Someone may say yeah, I feel better with low salicylate low oxalate, and then they think that’s just their life sentence. But that’s really boring over time. And I think there are beneficial antioxidants in the foods that you will miss out on. So I think it is important to be able to have a very diet. I’m a huge fan of animal based diet, but I’m still wanting to do some nuts and seeds and blueberries and maybe some starch here and there. Here’s one interesting thing I wanted to read, which is that excess salicylates work similarly in the body as oxalates that they both can lead to inflammation. And what they’re going to do is they’re going to create the overproduction of leukotrienes. And these are inflammatory mediators that can increase the risk of health issues like asthma and inflammatory bowel disease. And you also mentioned skin issues. So I’m sure the histamine connection is is definitely part of it, too. And that’s why we see benefit with things like course attend or natural anti histamines with these type of people, they tend to do better.

Dr. Justin Marchegiani: Yep. 100%. Because what you’re having, we’re having a major effect on modulating the immune system. So that makes a big difference, right. And then of course, making sure we’re able to break down our foods using things like an instant pot to help break down the foods. Be careful of things like crock pots just because the longer cooking can increase histamine. A lot of people who are sensitive to these females or salicylates or oxalates, or fight dates, they also tend to be histamine sensitive. So it’s kind of it’s overwhelming for people out of the gates that have a lot of immune imbalances because they really have to restrict a lot of stuff. And so, you know, some have to go to carnivore, they need fresher meats, they need to cook it up in a more fast way. And we did not have a lot of leftovers hanging around for days later because of the histamine accumulation. So those are the things you got to be very, very careful of. Also people feel better fasting, that’s also a good sign. When you’re fasting, you’re not eating any food. So you’re also not eating the things that are making you sick either. And so a lot of times, part of the reason why fasting is great for a lot of people isn’t just necessarily because of the cellular autophagy and the insulin resistance and all those mtorr pathways, you know, being reduced. It’s, you’re just not eating things that are making you sick, even if they’re healthy things, you know, like blueberries and your daughter, for instance, no one will be like, Oh, that’s like, that’s like junk food, of course that make her sick. No, that wouldn’t go on most people’s radar screens, but we know that there’s some anti nutrients that could be a driving factor in that.

Evan Brand: It’s interesting how berries, if you think of the just amazing evolution of fruit, and you think of the most vulnerable, most soft, easily ruined fruit, you’re going to think of the berries. I mean, you think of raspberries, I mean, I’ve seen countless times where I pick them up at the store at a farmers market. And man those things in less than a week those things are going moldy, they’re getting soft and gooey. So make sense why salicylates are so high in the berries, because essentially what it is, is a natural pesticide, and it’s an antifungal. So the goal is, the plant is trying to protect itself so that it can get to the proper stage and development that it wants to. So what does it do? Well, it doesn’t have teeth to bite the offender. So it has to create some sort of mechanism. And that mechanism is salicylates to protect it versus something like an avocado. It’s got that nice outer shell protecting it. So it doesn’t have to be as high in salicylates because it’s already protected. So that’s just a really cool thing to think about how nature works.

Dr. Justin Marchegiani: And then animals don’t have any of that, because animals have teeth and the ability to you know, fight back from a certain bit. So you have less anti nutrients on the animal side. And that’s why you see a lot of these carnivore groups pop up that are like, Oh my gosh, like look at all the my autoimmunity is reversed. Why? Well, it’s because animals don’t have the need for anti nutrients because they have claws or hooves or can run and and can fight so to speak, right. And so you have less anti nutrients and a lot of these animal products. So when you see a lot of people reversing significant autoimmune condition with carnivore or semi carnivore diets. And again, a carnivore diet is an autoimmune diet. It’s an it’s a low fodmap diet to it’s also those lists laid, so it’s low anti nutrient as well. But you see these stories, and the question is why? And most people, they’re very dogmatic about it. It’s like, Oh, no, it’s this diet. This is what did it and they don’t really understand the mechanism mechanism of what’s actually happening. biochemically and physiologically, they just kind of a look at it more like a religion than it is. But let’s just break down the science, right? Let’s look at reason, logic and evidence. And so the reason logic and evidence is reducing these anti nutrients. And then also we chatted about our show, a lot of times the salicylates and females and anti nutrients become more of a problem is when we have low sulfur a low glutathione to run a lot of our detoxification pathways. And a lot of times these sulfur nutrients have a major effect on modulating our immune system too.

Evan Brand: Yeah, well, here’s the interesting thing. You’ve got these people that are going on the diet, so I need to look them up. George St. Pierre, he’s a pretty- he’s a fighter, an MMA fighter. Yeah, yeah, he’s, uh, I don’t know if he still is, or if he’s retired, or what his deal is. But anyway, I’ve seen him posting that he’s gone to carnivore diet. He was doing like a 30 day carnivore challenge talking about how much better he feels. And he’s posting all these pictures of his, his steaks. And so like you said, it does become kind of religion, like, okay, it’s the vegan versus the meat group. But I think it’s more important to highlight, okay, he’s probably got something going on in his gut that’s driving his autoimmune issue, or whatever his issues were, that led him to more meat based diet. And you could do meat, meat, meat and remove all the anti nutrients, sure, but what did you not address and that’s the problem that I have is when people are gonna go and just eat a grass fed steak twice a day. And that’s it for their diet, or maybe a handful of this or that they’re still missing, the deeper thing. So let’s talk about that. Let’s dive into more of these bigger things. Because people are not going to investigate it, they’re just going to do the diet, they’re going to feel better and that’s as far as it goes, they’re never going to talk about what you and I are hitting on which is you mentioned.

Dr. Justin Marchegiani: I’ll just hit one more thread one more thread real fast people that would go on like let’s say a meat only diet or carnivore based diet, and they feel worse. Why is that right? They’re gonna just think oh, it’s the animal products is it it’s like no animal products are very taxing on your digestive system. So if you have an adequate C’s and HCl or enzymes or even bile salts, that weakness will be exposed by eating the meat cuz you may not have enough acid or enzyme or bile to break down that protein and fat. Therefore that foods going to feel like a brick in your stomach. You’re going to feel indigestion you’re going to feel bloated, you’re going to feel motility issues, and so that could throw you off too. So if you are going to go carnivore and make changes in these diets, low hanging fruit always is going to be how we cook the food, even if it’s plants, right because just steaming and putting our plants in some kind of a stew or soup, or just even roasting it way better than raw and then of course, enzymes and acids in between. By all of our stool is not being broken down. Well, if it’s floating, right, those are all signs of not breaking down fat. And so we have to really make sure those foundational pieces are addr essed.

Evan Brand: Oh yeah, that’s a great call. Because you’re going to have, you’re going to have a large percentage of the people that that do great. But then you’re going to have these people say, Oh, I tried carnivore, and I felt terrible on meats. It’s not the meats you’re pointing out, it’s not that I just want to say in a different way, it’s not necessarily the meats. That’s the problem. It’s your system can’t handle it. Everyone system can and should be able to handle meats. This is what we evolved to eat. But it’s it’s the matter of the underlying infection. So like the H. pylori, reducing the stomach acid, now you’ve got low HCl, you’re going to try to do meats, meats, meats, you’re probably going to be having tons of gas, you might have diarrhea, because you just simply can’t break down the the fat in the protein and you and I are going to measure this right? We’re not going to just say, hey, try this diet, or try that we’re going to do the testing to investigate and what we may see on the stool, we might see high, stouter crit, which is a fecal fat marker, we may see low pancreatic elastase, we may see high calprotectin. There’s gut inflammation, and then we may see these root causes which I want to transition into the bacterial overgrowth, the parasites, the worms, all these infections, which are disrupting the gut, creating the leaky gut, which is then allowing the histamines the oxalates the salicylates to become a problem. So let’s dive into one thing, which is mold toxin. We know that mold toxin is definitely going to affect detox ability and it can create a mast cell problem and I’ve dealt with mast cell problems myself I’m slowly but surely getting better and better and better by doing two things. Number one, eliminating the mold toxin using binders. And then number two stabilizing the mast cells using things like coarse attend, and other mast cell nutrients nettle can be helpful vitamin C to help degrade histamine do with food to help digest the histamine you’re putting in the diet. So I think toxins in general, maybe not just mold, but I think we could say toxins, heavy metals, pesticides, herbicides, anything that’s disrupting the gut is going to be important to to look for with testing and then to treat.

Dr. Justin Marchegiani: 100% Yeah, especially if you can get to the root cause, right? If you’re in a moldy home right now, we got to look at that we got to address it. If you have high levels of mold out of the bat, but you’re not in a moldy home, it may be less important to jump on board with detoxification if you already have a lot of crappy digestion issues going on. Because we know a lot of molds going to be eliminated via the hepatobiliary system. So a lot of times we got a time up isn’t the appropriate time to really push and lean on detoxification. That’s an important thing. We live in a generation where we know if we have some kind of a toxin exposure or some kind of a gut, Bob, we want to go after that right now. And sometimes we got to set the table for it get the foundation moving, so we can manage that better.

Evan Brand: Yeah, well said. So let’s chat on the solver piece. You brought up sulfur. So what are things we can do to boost sulfur? Because this is going to help with the solicita a problem. And then also, you know, I know, you know, boosting sulfur is going to help with detox. Right? And it’s going to help boost glutathione production too.

Dr. Justin Marchegiani: Great question. Let me share my screen here. So you guys can see some stuff. Alright, so this is one of the eating plans that I made, you know, over the years, I’m changing it all the time for my patients to kind of help them give them good feedback. But the key thing is we got to have healthy levels of protein in every meal. All right. And so typically, I’m doing a palm to a fist to a full hand of protein. Now if I have someone coming in with really crappy digestion, and there may be a previous vegan, they may only be able to handle like one bite of like salmon or something, right. So this is like a general template, but it may not work for everyone. Depending on how bad your digestion is. I always tell patients, the worse your digestion is we lean to like gentle stews, and soups where it’s just easier on the body easy to handle. And I try to you know, eat enough. So someone can last about four to five hours. But sometimes if their digestion stinks, they may only be able to eat enough for two to three hours because a smaller amount of food less food in your tummy. And then you just come back more frequently, right? It’s not ideal in the you know, intermittent fasting insulin sensitivity world, right, because you want to have more time between meals and not be grazing all the time. But from a digestive health standpoint, that may be what’s necessary. And then in general, just to look at my eating plan here, healthy proteins, healthy carbs, right, and you can see some of the carbs that are going to be higher in fodmaps. Right, you can see some of the autoimmune foods that are in red, right. So we want to avoid the red the autoimmune foods, we want to be doing more of our non starchy vegetables without the F’s next to them, ideally cooked steamed sauteed and then avoiding some of the five maps right now, for my patients. I have an expandable fodmap handout here. So it’s just it’s more in depth right? You’ll see this come up in a second. This is helpful here is also a great app that I use for things that may be more nuanced called fodmap. A to Z that’s a great one. And then we use some of these oxalates like we’ll look at some of the like I try not to overthink it with the oxalates I just try to look at and say like what are the top three to five things that you’re doing? Maybe on the oxalate side or on the silver This late side, if they’re really sensitive, right, we may just jump onto a carnivore diet and automatically eliminate these, we may just look at these more specifically. And let’s just let’s highlight the ones that are the Most High. Right, and this is one given out by University of Pittsburgh Medical Center. But you can see, we just try to look at the high ones and try to just replace them with a low one. If we’re seeing someone like let’s say, consume a lot of teas, right? or seeing someone do a lot of nuts, right. And again, if you do like an autoimmune paleo template, guess what happens, you’re already cutting out all majority cutting out nuts, you’re already cutting out soy, right? So a lot of times we get a reduction, doing some of like, you know, the the templates that I talked about here, my meal map, just naturally, okay. And then of course, if we have a lot of eczema issues, we may also be looking at this as well and trying to look at some of the higher salicylate foods here. And again, it gets overwhelming. So if you’re, like I mentioned earlier, if you’re coming into this with a standard American diet, and you’re not that great to begin with, don’t worry about this, like, forget about it, just get a good foundation, once the foundation solid, and you’re not quite moving the needle. This is where you work with a practitioner to get to the next level. So I just don’t want anyone coming in that doesn’t have a great day and looks at this. And it’s like holy crap, like, forget this. This is too confusing. Don’t worry about that. Push that aside. This is for people that are already kind of flatlined on that and there are options. 

Evan Brand: Agreed. Yeah, well, you mentioned AIP is going to be eliminating a lot of this stuff anyway. So really, we’re talking about just other terms, other names for diets that have tons of overlap. That’s the key thing that’s coming out of this is like whether it’s animal based, whether it’s full carnivore, whether it’s autoimmune. There’s so many overlapping things that are happening, you’re reducing toxins, you’re reducing anti nutrients, overall, you’re going organic as much as possible. So I think it’s important for people not to get caught up on the name or the term of what, quote, diet you’re eating, we just want you to focus on what is going to make you feel the best. And in general, that’s going to be organic pastured meats. And like you mentioned, if you’re coming as a vegetarian, vegan, maybe you can only do a bite of a grass fed burger at first, then we uncover you have all these gut infections. Now we fix the gut infections boost up acid and enzymes. Now you could do a whole grass fed burger and you feel better than ever, compared to your 20 years of being vegetarian, for example. 100%. Let’s go back to the sulfur though, those handouts were helpful. Let’s go back to sulfur for a minute though, things that we can do we know like foods, for example. So like onions, garlic, which these may be fodmap foods, right? So then we’re going to coach you through this if we’re working with you, but we want to go higher sulfur, so eggs are going to be good if you tolerate those, if you’re on AIP, obviously, you’re not so eggs. 

Dr. Justin Marchegiani: So out of the out of the gate here, like your proteins are going to be excellent for sulfur, right? They’re going to be very high in cysteine. And a lot of the sulfur based amino acids, so any of your fish eggs, if we can do it, darker cut meats are going to be higher, better in a lot of the sulfur amino acids, some of the vegetables that are going to be more sulfur rich, they also may be higher and fodmap. So you have to look at that collard greens, kale, they may be good, but they may also have some of these extra salicylates in there. So we have to look at the vegetable component. And we have to look at the meat component. So the easiest thing out of the gate with silver is just meat if we’re sensitive, because we’re not going to get the anti nutrients on the meat slash protein side. And the key thing is if we have digestive issues, we really have to lean on enzymes and acids, and maybe bile if our stools floating or it’s taking excessive wipes to kind of clean yourself after number two. So we got to look at those things right got to make sure we’re breaking everything down out of the gates there. And then outside of that, just making sure motility is good. If you start eating more protein it like start moving in the carnivore side, you may not have passed as much stool just because a lot of this is going to be reabsorbed and not necessarily come out via fiber in your stool. So stool kind of motility may drop a little bit and that may be on the normal side. Anything else you want to highlight here Evan?

Evan Brand: Yeah, well, here’s something interesting the point that we kind of have this convergence of diets and it really just shows how sick and symptomatic the population is because AIP used to be good enough. And now people are taking it to what I would consider almost more extreme level where they’re literally just doing meats. And of course hopefully a lot of those people can do more animal based which is what I would say my diet is animal based but then I have other foods. But man if everyone is having to go from us to AIP used to clear everybody up now we got to go carnivore to clear people up that just goes to show just how sick as a population we really are, it’s really quite alarming.

Dr. Justin Marchegiani: It is absolutely is and people need to remember like animal products are nutrient dense. So if we’re just relying on muscle meat, that’s okay, if you’re going more carnivore, try to lean into some bone broth if you can try to do a little bit of work in meat or at least some origami capsules. And you really got to be careful with getting extra enough magnesium and potassium because a lot of times those are going to be more in your green vegetables and plant in plant foods. So if you’re going to be decreasing some of those things, you just got to make sure supplemental You have a good magnesium potassium support. You’re putting a lot of sea salt in your water and or on your meat when you’re seasoning. And so just got to be careful with those electrolyte things which can be easily missed.

Evan Brand: Yeah. So how do you boost sulfur to help the salicylate problem we hit on the proteins, we hit on some of the other foods like maybe some garlic, baby, some onion, some broccoli, things that are going to give m-

Dr. Justin Marchegiani: Yeah, and those are going to be high in fodmaps. So again, we have to dovetail that this is where having a clinician than a help adding an HCl adding an enzymes being able to break down those foods, adding in collagen, amino acids or bone broth, which is very high in glycine, which is very sulfur, we may need to add in some things like n acetylcysteine. Again, it may not be great out of the gates, NAC is also a biofilm buster. So a lot of the high sulfur stuff can also knock down biofilms for the bacteria. So it just depends kind of where people are out of the gate. So what I tend to do is add in some gentle collagen, amino acids, or some freeform amino acids in a capsule form, maybe some bone broth, you know, as long as there’s no histamine issues, and really lean on digestive support, I’m going to do that out of the gate. And then maybe when it’s time to do gut killing, maybe we’ll add in some extra and acetylcysteine or sulfur amino acids, whether it’s just straight NAC or I have a product called detox amino that has calcium digluconate in there, which is great for beta glucuronidation mold detoxification too, and has a lot of all the other glutathione and NAC and methionine and cysteine and taurine, all those good things. So it just depends out of the gates, maybe we’re just focusing on food, supplemental freeform amino acids, collagen, and really working on digestion.

Evan Brand: Yep. And if you’ve got a kid too, and you’re trying to work stuff into their system, and maybe a little harder Epsom salt bath could go a really long way. And then life is almost Bluetooth ion in a liquid form. So there are some really good like syrups and some things that you and I use clinically, which can be helpful. So it’s not mandatory that you go to the Bluetooth ion level. But that is a really good way to help a lot of different mechanisms because you’re going to be mobilizing and pushing toxins out and protecting them too. It’s a really powerful antioxidant. So we really like gluta fine for kids. And typically we’re going to go like a quarter of an adult dose depending on the weight of the kid. So if it’s a young kid we’re working with, you know, if a normal dose is a teaspoon, we may come in quarter teaspoon instead, or maybe we go half a teaspoon. And then also you mentioned magnesium, so we could do magnesium oil. You could do magnesium lotion, you could do magnesium drinks. If you could get your kid to drink some magnesium. There’s some good options there too. 

Dr. Justin Marchegiani: Yeah, magnesium is very helpful for brain inflammation. Right. Russell Blaylock, retired neurosurgeons talked about the fact that when he would give his patients magnesium post brain surgery, they healed exponentially faster compared to people, patients he didn’t give it to. So we know magnesium, very, very powerful brain inflammation. Obviously, if you have gut issues, doing Epsom salt bath absorbs it trans dermally, right. flotator flotation tanks, same thing, very helpful. And again, if you’re a mom or dad, and you’re listening to this, and you’re just trying to get your kids eat blueberries away from the crackers that do that first, right, do that first. I mean, he does a lot of studies on eating blueberries and some of these low sugar fruits and being incredibly anti inflammatory to the brain. Go there first. If you’re having a reaction, then we step it up into gear. So my son was born, I think it was it was last year, he was six months old. And he was having a lot of eczema issues. And we had to really work on going AIP and lo salicylates to get the eczema down. Now, once we worked on gut and digestion and good bacteria balance, we were able to add these foods back in, and it wasn’t as big of a deal. And when you’re younger, at that age, there’s some immune issues that tend to happen in that first year life until we were able to get through that point. And it was excellent. And it really never came back unless we eat certain foods that we know are not on his plan. But out of the gates, we had to be more restrictive with salicylates, and then we were able to pull back on that down the road.

Evan Brand: Well, the guts more leaky as a young baby like that anyway, right. So I think it’s somewhat normal to have to be a little bit more restricted with young kids because their guts are forming so they can really absorb all the breast milk. So I think you did a good job. And I think this is important to remind people that all these different tweaks, these are really just tools, but really, you got to get to the big thing here, which is a mast cell problem, generally a mast cell activation that’s causing you to be so darn sensitive, whether it’s chemical sensitivity you deal with, which could also be common. So if you have if you notice, you’re having salicylate oxalate problems, histamine problems, you could have maybe chemical sensitivity or other reactions as well. And you got to get to the root of it. For me, the root of it was tick bites and mold. And I’m slowly chipping away at those things. So I think you just got to keep dig digging deeper. Don’t just stop at the die and get the diet dialed in enough to have you stable. And then once you’re stable, you’re going to investigate these other things. Don’t just do diet and think that’s the end of the road for me. I’ll just never eat blueberries again. That’s not a way to live. 

Dr. Justin Marchegiani: No. And again, those foods are relatively healthy and they’re very nutrient dense. There’s a lot of good phytonutrients in there. So if we can have it in and plus, you know, I’d much rather have my kids eat blueberries and crackers or any other sweets, that’s always better. So, yeah, so we got to, you know, we got to make sure we’re seeing the forest to the trees. You So we have a big picture where right we’re focused on what our what our goal is now but then what’s the big picture in the long run?

Yeah, so just to wrap up last, last thing on the testing front, we’re going to look at an organic acids on your we’re going to look at Candida, we’re going to measure oxalates. We’re going to look at bacterial overgrowth, we’re going to look at stool for any type of infections gut inflammation. We’re going to look at any type of pancreatic enzyme deficiencies we’re going to look at fat digestion problems, so just was stolen urine To be honest, I think you could get a ton of information.

100% man, why anyone listening and you guys enjoy the content. Please feel free and share it with family and friends. Give us a share on your social we really appreciate it. Put your comments below let us know what you’ve done that’s been helpful for you in the past. Also, if you want to reach out and get support from Evan and I we are available worldwide love to be able to help you. We’ll put links down below EvanBrand.com. Reach out to Evan. JustInHealth.com and reach out to Dr. J myself. We are here to help you ready to serve. You guys have a phenomenal weekend and we’ll be in touch. Take care now. 

Evan Brand: Take care. Bye


References:

https://justinhealth.com/

https://www.evanbrand.com/

Audio Podcast:

https://justinhealth.libsyn.com/are-you-sensitive-to-antinutrients-salicylates-and-oxalates-in-plant-food-podcast-336

Recommended products:

Detox Aminos

Antioxidant Supreme

Magnesium Supreme

TruKeto Collagen

Trucollagen (Grassfead)

The Affects of Mycotoxins On Male & Female Fertility | Podcast #318

Mycotoxins exposure from food occurs globally but is more common in hot humid environments, especially in low-income settings, and might affect pregnancy outcomes. However, frequent mold contamination of maternal diet can therefore affect anyone. In this video, Dr. J and Evan talks about mycotoxins and how it can affect men and women’s fertility. 

Dr. Justin Marchegiani

Dr. Justin Marchegiani

In this episode, we cover:

2:52        Zearalenone, Mold Toxins

11:38      Mold Toxins from Food and Grains

14:32      Binders

21:20      Fertility Issues

27:13      Detox Support

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Dr. Justin Marchegiani: And we are live. It’s Dr. Justin Marchegiani in the house here with Evan Brand, Evan, how are we doing today my friend? 

Evan Brand: Doing awesome, ready to dive in, have some fun together. So you and I, we don’t really market ourselves as like fertility doctors, fertility practitioners, anything like that. But we’ve both between us had many successful healthy babies not only in our own family but that our clients have had. And it’s interesting because fertility really comes as a side effect of getting healthy. And so that’s the first big key point of today. When you look at the fertility industry, you’ve got the in vitro fertilization, you’ve got all these shots, all these different drugs. They’re not they’re not really addressing root cause in most cases, most cases, they’re just trying to come in and just find a way to sort of short circuit or hijack the circuitry to make a baby happen. But we would argue there’s a better way, which is get someone healthy, and I was looking into I’m doing a mold presentation, and I was looking to do some research on mycotoxins and something that you and I test for via urine are various mycotoxins and there’s one in particular called z everleigh, known z like zebra z everleigh known, and this is a highly, highly, highly estrogenic mycotoxin, far more estrogenic than soy. And people freak out about soy and they should but nobody freaks out about z or linode. And that’s really, to me the bigger issue and so we have a paper here that we found called maternal mycotoxin exposure and adverse pregnancy outcomes, and there’s many many papers on this. This was just a review of them. And it was talking about the different mycotoxins so anything from aflatoxin, to okra toxin to Fusarium based toxins. And here’s what can happen. hypertensive emergencies in pregnancy, neural tube defects, increased risk of preterm birth and late term miscarriage, neonatal jaundice, impaired fetal growth. And I mean, just straight infertility. So, when we see women that are infertile, I mean, I just look at some of the friends I had from high school and college. And many of them have had issues with fertility. Some of them did IVF. Some of them had miscarriages. Some of them had pre preterm birth at a friend actually just have a baby and their baby showed up six weeks early like wow, what is her Mold Test look like? So this is a really, really big piece of the puzzle that I think people are missing. And we’re inside all the time, right? We’re on technology. So we’re inside a lot more than we used to in the farmer days. And so now we’re breathing this stuff in all day, whereas before, it maybe would have only happened when you were sleeping in the farmhouse. But during the day, you’re out on the farm. 

Dr. Justin Marchegiani: Oh, yeah. 100% Yep. 100%, the zerion alone. mycotoxin is that’s made by the Fusarium fungi. So it’s a mycotoxin actually made by that level of mold. And it’s in the food and it’s in the in the the animal feed. And that animal feed is designed to fatten those animals up. So I have one kind of study here. It’s called zuranolone. All the study is called by Science Direct. And it’s looking at the absorption of zuranolone on body weights, and how it increased the size of the pigs 15 to 25 kilograms. And basically, it increased body weight. And then one of the big things they found with zuranolone. In reproductive tissue, it actually decreased. Fertility is one of the side effects of this study. I’ll pull up the exact study on screen here in a minute, I have it up here in front, I’ll find the exact paragraph on there, and I’ll show it to y’all. But mold toxins is going to be one of the big conversations here with fertility. Now we can plug that into xeno, estrogens and plastics, we could potentially plug it into pesticides as well, which are going to be found in food. We can plug it into growth hormones and milk and dairy and hormones and animal products. The problem is it’s all a hormonal stress load. It’s not just one thing. So when you look at different studies on one topics on one thing on one toxin on one hormone on one mold, it may not be enough in one person or globally to pop up as an issue. I mean, here we’re finding studies on an off the bat. But we know it’s all about your stress load. And so I want to get people’s mindsets kind of around that stress, that metaphorical stress bucket and all of these different toxins, whether it’s mold, or pesticides or hormones, or plastic type of hormones, they’re all adding into that big stress bucket. And of course, fertility is going to be significantly impacted by that.

Evan Brand: Yeah, well said, here’s something crazy, too. It’s a little bit related. You and I were looking at this a little bit ago. The onset of puberty is massively dropping. So why am I bringing puberty? Well, because this is connected into hormones, and what’s happening with hormones. So in 1860, and you had a graph of this, that was really cool, too. But in 1860, the average age of onset of puberty in girls was 16.6 years. So over 16 years old, 16 and a half years 1860. That’s puberty. In 2010. It is now 10 and a half years old. That is insane. And that’s probably the most I mean, I can guarantee you that’s the most rapid change in puberty age in in human history. And it all happens less. And it all happened in the last What’s that about? 100 and 150 170 years. That’s insane, right? Isn’t that crazy? I’ll pull that graph up here for everyone to see here. So you guys can see it. I think now really important to visualize. Yeah. Now while you’re doing that, they’re just talking here, just like you said, there’s this really this stress bucket, so endocrine disrupters, various chemicals in the environment, acting on hormones, widespread industrial and pharmaceutical pollutants. I mean, there’s a lot of stuff here. diagnosing recently high in sugar and fats declining physical activity. Yeah, here’s the graph. So people listening, you’re not going to get to see this, but the graph is pretty nuts. 

Dr. Justin Marchegiani: Yeah, so you can see here the, the y axis, the up and down access, so you can see the age right 16 to 15. And then you can see the x axis is time. So as we go from the 1860s, up to current day, you can see we kind of flat plateau between, you know, 13 ish, 13 ish for puberty age versus, you know, 15 to 16. And a lot of that has to be influenced due to mold toxins, and some so here’s one article here that Evan talked about here, maternal mycotoxins, and again, mycotoxins are toxins produced by the mold. So a lot of times, it’s not necessarily the mold that’s causing the problem. It’s the toxins produced by the mold. So it’s good to look and test for mold, but also test maybe for the urinary mycotoxins as well, but you can see exposure and adverse pregnancy outcomes. And and this is a very interesting study talking about increase in puberty, increasing in puberty age, like I mentioned, also fertility, right. preterm birth, late miscarriage inclusion, some evidence for toxins or pregnancy may have detrimental effects on pregnancy outcomes. Now, of course, there’s limited studies, right? No one makes a whole bunch of money, studying this kind of stuff. But we know it’s, it’s there. And there’s some data already on it. And we also have a lot of common sense. We know something’s a toxin, and can affect the hormones that it makes sense why that may be effective. 

Evan Brand: Yeah. And I’ve seen several women who are going through a protocol spontaneously get pregnant, which is really cool. Now, some of these women came to me with the intention of getting pregnant. They’re like, Hey, you know, I’ve been told the fertility specialist are unable to help me. Can you help? And I’ll say yes, Probably so. And then some of these women just had spontaneous pregnancies as an accident because they thought they were infertile. They thought they can’t get pregnant, we put them on a protocol, and then all of a sudden they get pregnant. So let’s go into some of the the action steps. I mean, what are we doing for these people? I think it’s important to know about what we what we discussed is everyone owns bad news affects hormones affects fertility affects puberty. But what do you do about it? So as you mentioned, number one, we’re going to be testing the environment. So using-

Dr. Justin Marchegiani: Hold on one thing, I want to go a little bit deeper into what you just said, we talked about some of these mold toxins and in fertility, right, we have this one study here, which we already mentioned, which is maternal mycotoxin exposures and adverse pregnancy outcome, which is a new new study, right? mycotoxin research may 2020. That’s important. And this is actually on humans. There’s lots of studies on zearalenone,  that’s i’m pronouncing that good in farm animals, because it’s been used in farm settings to fatten animals up for many years to the feed. So there’s a lot of data on this. And that’s important. So we know for instance, studies on in vitro effects allowed to understand the mechanism of action, right in vivo means the actual animals, and they see an impairment of semen quality and female reproductive function. So we talked about fertility, right? Most people think of fertility as women, right. But we know it can affect men as well. And it takes two to tango, right? And zearalenone could be a factor responsible for Reproductive failure in farm animals. And so if you go to the reproductive MD, are they going to be testing you if you’re having issue with pregnancy for mold toxins? Probably not. And look here, one study here, under allanon. Here, if you look here on the bottom part, so zearalenone is a nonsteroidal estrogenic mycotoxin. It’s produced by several species of the fusarium fungi, okay, so it’s produced by this Fusarium fungus, it’s a mycotoxin. And you can see here it’s supposedly it’s not it’s low in grain content, but it’s the storage of a lot of the grain where the moisture is greater than 30 to 40%, where this mold and fungus is produced, okay. And then right here in this one part, typical clinical signs are hyper estrogen ism, which explains the increase in puberty. Are the decrease in puberty age, right? More hormones sooner in life increases puberty, swelling of the vulva mammary gland hyperplasia, secretions prolonged uterus, increase in pseudo pregnancy, infertility, decreased libido, complications of rectal prolapses, stillbirth, small literary. So we know it has a lot of fertility issues. And a lot of the studies first tend to happen in animals. So it’s good to know the data here in animals, as well as some of the human stuff here we talked about earlier. 

Evan Brand: Yeah, the whole thing’s crazy. I mean, it’s hard to believe they would use this in the feed. I mean, like you said, maybe not intentionally, but it’s kind of a byproduct of storing grain in a, you know, in a moist thing. I mean, it’s like, you’d have to have a dehumidifier on your grain, or how about you just pasture your animals? So you don’t need to feed them moldy grain? How about that? 

Dr. Justin Marchegiani: Yeah, I mean, I can tell you one story I had with Dave Asprey. He told me and I can’t find the data on this, but they would use zearalenone pellets, that put the pellet in the cow’s ear. And that was enough to cause this increased fat absorption. Because those hormones were so concentrated, they were going into obviously, the the blood supply via the ear, and it was causing the animals to get fatter. And of course, farmers, you know, sell their animals based off of weight. So we know that zearalenone may even be used in a way outside of just Incidentally, in the fee, we know, it may just be there to fatten them up as well. 

Evan Brand: I’ve heard that too. I can’t find anything on it. But if any old school farmers are putting zero unknown pellets in your cow’s ears, let us know. Tell us about it. Give us the story on it, because we’d like to like to share this stuff. 

Dr. Justin Marchegiani: Yeah, I know. It’s totally interesting. I believe there’s something to it. I believe, you know, someone like Asprey wouldn’t, wouldn’t say that unless he had some actual good info on that. But very interesting. So off the bat, we have mold toxins, we talked about that. And that’s important. Now again, and humans, you could get mold toxins from eating crappy grains and crappy food. So eating foods that are going to have lower mycotoxin counts, and to be important. So you know more from vegetables more from fruits more from high quality, fresh pasture fed animal products, good high quality fats, that’s going to decrease a lot of your mold and mycotoxin and xarelto load right there out of the gates, okay. And then the next component is going to be making sure your house isn’t moldy. So if you have a history of water damage, or flooding, you want to make sure you go back and listen to our podcasts on looking at and dealing with mold and mycotoxins in your home. But of course, any history of water damage, or any leaks, you want to leave or any visible mold, you want to at least get a really good high quality amino Linux plate test that looks at the mold as well as mold toxins. I’ve had some patients that have ordered the plates and just say, Well, I’m gonna let it culture and just look at it myself. It’s like, well, you want to send it to the lab, because you want to know what the mold species is. And if there’s any mycotoxins associated with that mold species, because you may look at it and see the culture, right. But you may not know if it’s a friendly mold or not. So you want to know if it’s Is it a, is it a mold that’s from the environment and the soil? Or is it something that’s actually from water damage type of mold species? That’s important to know.

Evan Brand: On a retest, it’s probably fine to do the self test, because you can look and just see this, hopefully, colonies show up. But yeah, on the initial I tell people the same yeah, definitely. Because also too, we rarely find that the house correlates to the mycotoxin in someone’s urine. That’s pretty interesting. So that tells us most people are sick from a previous exposure, but in a few cases, we have found where the molds in someone’s house and the mycotoxins those would produce for example, Aspergillus and Penicillium producing things like okra toxin, mycophenolic acid, will then look at the house and see Oh, yeah, you’ve got a bunch of Aspergillus growing, that matches up to the urine. So it’s cool to see, but it’s not necessary to to get someone better. 

Dr. Justin Marchegiani: Yeah, I look at it just a tiny bit differently. Like if I see someone with a lot of mold, like weird kind of neurological symptoms, I always do the foundational things first, because a lot of times that can move the needle without having to go into any crazy mole protocols off the bat. But then if I see their home is very high and mold as well. You know, it’s easy, it’s sometimes it’s easier to decrease the exposure than to accelerate detoxification, especially if their guts not working well. So then there may be some easy simple strategies, like let’s just get a high quality air filter, let’s maybe get like a citrus bass, anti mole candle. If there’s any active leaks, let’s get someone in there that can work on remediation process, at least patch the leak or decrease humidity in the area. We can work on a couple of those things. And that can move the needle a lot. 

Evan Brand: Yep. Let’s go into binders. So this is where the magic happens. Like you said, you may need to do some work on the gut First, we may come in and help support the adrenals because detoxification it is work and it’s not easy, and you can get worse by trying to make yourself better and I’ve certainly overdone it on binders. I’ve certainly overdone it with glutathione and had a bad headache for a long time. So that wasn’t fun. So the good news is you can pull this stuff out of the body and in regards to that yerlan own, the some of the most effective binders are going to be your clays. Now charcoal can help a little bit so we often use like a broad spectrum you can come in and spot treat. And there are certain people that say you need to spot treat mold toxins meaning you need to use charcoal for okra toxin you need to use zeolite clay for zearalenone. But the truth is, a lot of people are not showing up with the true amount of mycotoxins on their first urine sample, meaning you may just show up with okra toxin, but you also may have zearalenone. But if you’re a bad detoxifier, you may not be urinating out all of those toxins. Therefore, I do kind of spot treat, if you will, but I still like to use broad spectrum full spectrum binders just because of this issue because what’ll happen is on a retest, maybe we took care of one toxin and then a new one shows up like well crap, we could have been addressing the other mycotoxin say we were just using charcoal for ochratoxin we could have been using a little bit of zeolite clay as well and that would have took care of the zero unknown but boom, now’s your will unknown shows up on the retest. Now we’ve got a whole new mycotoxin to focus on. So long story short, full spectrum, broad spectrum and multiple binders are what we like to use. And then I’m a huge fan of the micronized chlorella there’s a couple brands we use they have a liquid chlorella, that can be amazing. There are some tablets of broken cell wall, chlorella, that can be awesome for heavy metals as well. And then sweating. I mean, I tell you I feel much, much more clear, you know, clarity mentally, right after I get out of the sauna, you can have like a detox hercus reaction from a sauna as well. But if you’re healthy enough and you’re supporting adrenals you’re doing electrolytes. To me sauna is a game changer and even just a hot bath. If you don’t have access to a sauna, even if you just get hot enough to sweat in the tub. That may be a little too hard on someone if you’re weak adrenally like your constitution is weak. But or if you have blood pressure issues, you know, a hot bath may make you feel bad. But if you can do it, you can sweat you know it’s free, compared to a sauna may cost you 1000 bucks minimum.

Dr. Justin Marchegiani: Oh, yeah, I mean, you can always add in some, you know, really good magnesium salts like Epsom salts, which can be very helpful and relaxing for you as well. So yeah, so the problem is a lot of the binders that we may add in or if it’s necessary to add them, and they could also decrease or cause bowel motility issue. So if you already have a lot of bowel issues, this is why it’s so important that we kind of deal with the hierarchy. And a lot of times the gut needs to be fully addressed. And working so we can have good detoxification because the gut is so important. Hepatobiliary why’s liver gallbladder, it dumps a lot of those bile and toxins that are mixed in with the liver and the gallbladder back into the intestines, and it has to move out. And so we give maybe things like Evan mentioned, various pectins are activated charcoals, or clays or fulvic minerals to bind up a lot of these things. But if we have really slow motility, it could really jack up with our absorption of nutrition and a reabsorption of other toxins, we want to make sure our bowels are still moving. So some people may not be able to handle that. And also, you kind of alluded to getting a false negative on some of these urinary Mold Test. That’s why it’s very important that you probably do one to two weeks worth of glutathione ahead of a urinary mold test to make sure we’re adequately dumping it. Because people their detoxification may be so weak, they may not be dumping it, they may look to that Mold Test, hey, look, I’m good, but you may not be. So I do a week or two. And I tell patients that if you are really feeling crappy during that loading phase, you probably have some level of toxins, and may not just be mold, it could be other pesticides or metals or other things in the environment you’re dumping. But it’s always good to do that load period. And if you feel too sick or just too achy during that timeframe, you know, feeling lethargic, malaise, achy brain, foggy Moody, it’s probably not the right time to do any testing yet, maybe you want to wait a little bit longer, get things moving better, and test the home, see what’s happening in the home and wait a little bit more till everything’s working better on the detoxification side, just getting your diet better, decreasing your inflammation, improving your nutrient density, surprisingly, that actually moves the needle a lot. And then you could always add in some gentle sweating protocols like Evan mentioned as well. 

Evan Brand: Yeah, you know, you and I’ve talked about this for years, this idea that when people figure out there’s something going on, they want to take care of it immediately. Remember, we’ve done shows on parasites, and we talked about how, as soon as you see parasites show up, the the gut is, you know, the gut feeling is Oh my god, get this out of me and you and I’ve kind of discussed that you do want to do things in the correct order. And I would agree that happens with this toxicity issue as well. So if we’re working with a mom who’s had infertility problems, or you know, issues with pregnancy, and we want to help increase her health, we still are going to focus on the gut because there’s a right place in the right time. And if you’re really weak, you’re really sick, and then you try to go straight into a detox protocol. You could go the wrong direction. And it Trust me, I want this stuff out of you as fast as you want it out of you. But there is a right place in the right time. So we’re still going to be doing other testing, like looking at stool to try to investigate these gut infections. You know, you mentioned some of the reabsorption of toxins, too. That’s a big problem. If you have bacterial overgrowth because of this whole beta glucuronidation issue that we see. And so, there may need to be a month or two of just fixing the gut and fixing the enzyme production before we even get into detox. So don’t rush, don’t rush, don’t rush. That’s the whole message here. And can you do this on your own? That’s a question we get a lot. Well, can I just go online? Go on Amazon, buy a bottle of charcoal and be done with this? I would argue No, I will speak for Justin and say he would say no, as well, because we’ve done this 1000 plus times. And we know that if you’re just trying to detox and you’re not addressing everything else, you may send yourself backwards. What does that mean? Well, it means if you’re overwhelming your system, so like when I took charcoal, I’ve got some right here on my desk. I thought, well, I feel so good on four capsules a day, I’m going to go up to eight capsules a day. And I didn’t do anything in regards to my gut, my liver adrenals. And I crashed hard, I had way too much charcoal is like whoa, you can’t have too much of a good thing. So that’s why I would argue it’s better to have a practitioner kind of prep your body and build up the other pillars of health. Before you go into the detox pillar. detox is sexy, right? Like detox tea and all of this, it’s kind of a trendy thing to do. But people don’t have the disclaimer that you need to be ready, you need to have a constitutional strength to do this.

Dr. Justin Marchegiani: 110% I totally agree. Sometimes we detoxification slow and steady, is the better way to deal with the issues, especially if a lot of these issues came slow and steady. If they came over decades, then it makes sense. If it you know a little bit more of a short term kind of toxic issue, you could probably hit it a little bit faster and harder, especially if you’re younger and more healthy. That totally makes sense. So when we talk about, you know, fertility and mold, I know a lot of women out there are going to be like, man, I knew it’s mold, maybe maybe not. So I just want to make sure anytime we talk about a specific issue, and we connect it to a thing like fertility that resonates with women, right. Like if you have fertility issues, you know, it’s it’s a very stressful thing for women that want to get pregnant, and they can’t, it’s very, very stressful. And so you want to look at the goal of pregnancy holistically. So you always want to look at diet and nutrient density. And all of the building blocks in your food. And being able to digest those foods adequately is core foundational, you want to be able to get sleep and having high quality water, you want to look at mitigating toxins, whether it’s molding your food, whether it’s eating crummy moldy grains, whether it’s consuming a lot of hormones, or pesticides, you want to look at those things as foundational. And then we can look at the hormones, we can look at your luteal phase hormone levels, we can look at your adrenals we can look at thyroid, autoimmune gut permeability, gut infections, and then we can eventually work our way to detoxification. And mold levels down the road, there’s an order of operation. So just kind of look at things as what’s going to give you the best bang for your buck. I always tell my patients if you’re going bowling, right and it’s your first role, you’re not trying to hit the outside left pin, you’re trying to hit the pin right in the middle, why hit the pin in the middle and knocks everything else down. So it’s kind of that’s how we want to look at this and mold maybe a pin that’s off to the right or left with some people. Some people that may be the center pin, right. But we always go with that center pin. And that’s always gonna be the foundational things to start and then we build on that as we go. 

Evan Brand: Nice. bringing out the bowling analogy. That’s a new one. I like it. I like it. That’s awesome. Excellent. So for men, I mean men listening to they’re like, Well, you know, this is all about her. Nope. Did you hear the part about the reduction in sperm quality? So men, you are not exempt? I get frustrated with these fertility practitioners that people have seen before they come to me because why is the male not on this phone call? Like, this is so important. Why is the male not here? What is he doing? And so we know just the mold toxin, but anything else in regards to the diet, the lifestyle, the gut, that all affects male fertility as well. And I think this is really the missing piece. The women take all the blame the emotional blame the physical. I mean, it’s, you know, it’s a big issue for them to, to not have fertility, and so the men are just sitting back with their arms crossed, like, Oh, poor you, but they got to get involved too. And so there may be a male protocol that we’re implementing as well, a lot of the foundational nutrients for women, you know, we’re doing prenatals omegas, vitamin D, vitamin K, possibly some trace minerals, enzymes, electrolytes, liver support, did I say adrenal support already? adrenals. So those are some of the pieces that we’re implementing. And good news is, a lot of this stuff we’re talking about. It is reversible. Now, if you’re age 50 I’ve had some women literally age 50 52 coming to me because they want to have babies. I’m like, Ah, you’re 52 I’m gonna help you get healthy, but I’m not signing in blood. You’re going to have a baby at age 52 like this is Wow. So, you know, I think there is a cut off. But, you know, if you’re 40 listening to this, and you’ve had issues, I think you still have time.

Dr. Justin Marchegiani: Absolutely. So I mean, my wife, we had our first child she was 41 and then 43. We had no problem getting pregnant. For the most part. We had a little bit of a fertility snafu in the beginning because she had a fibroid that was kind of embedded in the uterine lining. We didn’t know about it and was just sucking a lot of blood flow. So I always recommend patients that have fertility goals just to get a good general fertility workup to make sure there’s no ovarian tube or fallopian tube blockages, no weird, fibroids or anything weird that endometriosis that could be affecting fertility, because those things are pretty easy to remove. If we have to surgically Of course, there’s natural ways to do it, but it takes time, right. So if you’re under fertility window, you don’t have years to help these things reabsorb on their own. Sometimes a surgical intervention can be helpful when the clock is ticking. But guys, it’s pretty easy to roll out guys, we can do a high quality sperm test we can look at motility how the sperm are moving, you know what percents moving forward, what percent not moving, what percent. moving backwards, we can look at shape, which is morphology, we can also look at overall sperm count. So sperm count cut off, I think most the average firm comm for guys is around 20 million, we want at least 50 million. So we can look at that and there’s also expanded sperm panels, we’ll look at all look at DNA damage. We’ll look at oxidative stress as well. Now the key thing with guys is going to be just making sure insulin resistance toxins are under control, maybe a little bit of lifting some resistance training, you know good quality organic food right enough protein, enough fat that tends to be enough for most guys, adequate Selenium and zinc right adequate levels of good amino acids like Argentine that tends to be enough to really support good healthy sperm count where it’s going to be high enough. We can also add in things like co q 10 and carnitine. Like I mentioned, to support it extra. So it’s pretty easy to rules rule guys out in the beginning, Okay, good, hey, we’re at an adequate level great. Oh, we’re not let’s look at DNA damage. And then we can always then look at toxin load. Or if a lot of the guys are eating conventional standard American or eating a lot of GMOs, we can we can tweak a lot of that we can run a specific intercellular nutrient panel to look deeper at the nutrients and work on spot treating those on top of a good diet as well. But that’s essential. I like to get that if fertility is a goal to get the guy ruled out right away in the beginning. 

Evan Brand: Yeah, that’s that’s great. Yeah. And that’s where like we said, Good multi comes in maybe some adaptogens too, because some of the herbs we use, they do have some supportive effects on hormone levels with man regulating testosterone estrogen levels, you know, some of the detox support may help in regards to estrogen. If men have had have a toxin issue and they’ve got, you know, breast tissue, they’ve got gyno, maybe they’ve done steroids. I mean, there are some issues that they kind of throw a wrench in the gears, but yeah, in general, you definitely make it sound like it’s much easier for men. 

Dr. Justin Marchegiani: Yeah, I mean, out of the gates, I mean, women’s hormones are just so much more delicate. They’re like a beautiful Symphony and men’s are kind of like a foghorn. As I’ve always said, and, and with a symphony. If you just have the string the strings off or the percussion instruments off, you know that Symphony could turn to noise pretty fast. Definitely. We want to make sure that that’s you know, fully dialed in. And we want to look at the toxic load. So really important if you women are listening and you want to dive in deeper and with fertility goals kind of being there or even energy your mood goals being there to write I recommend clicking down below you can schedule with Evan, EvanBrand.com, you can also schedule with Dr. J. Myself, JustinHealth.com, we’re here to help you here to serve. Here to educate, we recommend taking advantage of all the low hanging fruit, we try to provide tons of low hanging fruit in this day and age. Everyone has access to it based on you know, the internet and everyone having these smartphones that are so cheap. Now it’s great. So everyone can kind of get access to a lot of this great Intel and start applying it. And then if you want to dive in deeper if you want to start stop guessing and start testing and figure out what’s happening under the hood. That’s where I really urge you all to reach out. And if you’re enjoying the content, please refer us to friends and family and shoot over a podcast the best way you can thank us for all that we’ve done is just kind of send the content to your family and friends so they can get healthier. Evan, anything else you want to say man? 

Evan Brand: Yeah, that’s all I want for Christmas is for everyone listening to share the podcast with your friends, your family, let’s make 2021 and even better, healthier year, less stress, less worry, more health, more vitality, it’s all possible. We try to give you guys action steps every time and this stuff is free. I mean, it’s a thankless job. So the best way you can think of sharing is caring. Thank you so much. 

Dr. Justin Marchegiani: Thanks, everyone. You guys have a phenomenal holiday season.


References:

https://www.evanbrand.com/

https://justinhealth.com/

Audio Podcast:

https://justinhealth.libsyn.com/the-affects-of-mycotoxins-on-male-female-fertility

Mold Problem?

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Best Herbs for Lung Health

By Dr. Justin Marchegiani

There are many contributing factors in the health of your respiratory system, such as the lungs. These factors include diet, genetics, environmental factors, physical activity level, allergies, and more. Today I want to share some of the top herbs for respiratory health which have been used over centuries to treat sore throats, wet and dry coughs, the immune system, and more!

Best Herbs for Your Lungs

Astragalus Root

Astragalus Root is a great herb for those who have a weakened immune system or can’t seem to stop catching colds. People who suffer from chronic illnesses, particularly relating to the respiratory system, can try incorporating this medicinal herb into soups and teas to help improve immune system function.

Raw Garlic

Raw garlic is a powerful anti-inflammatory and antioxidant and  should be a household staple! One study done in 2013 found that participants who consumed raw garlic at least twice per week had a 44% lower risk of developing lung cancer than those who consumed raw garlic less than twice per week. To activate raw garlic, you should lightly crush or chop the cloves and allow them to sit for 10-30 minutes, during which time important enzyme reactions take place to ‘activate’ medicinal properties. You can sprinkle raw garlic over foods like steak or salad.

Ginger Root

Ginger root warms the lungs and increases circulation and blood to the lungs which can help with respiratory ailments. Ginger has been shown to be effective at protecting the lungs from inflammation, mediates the immune and allergic response, and is great for the immune system!

Green Tea

Research shows a possible link between green tea and a lower risk of chronic obstructive pulmonary disease (COPD), progressive lung diseases that can cause troubled breathing, coughing, wheezing, and shortness of breath. Green tea is full of antioxidants and polyphenols which benefit lung function, such as epigallocatechin gallate (EGCG), which studies show can help suppress lung cancer cell growth, and theophylline, a ‘bronchodilator’ type of compound which can improve airway function. 

Licorice Root

Licorice Root is a demulcent herb–meaning it relieves mucous membrane irritation. It has traditionally been used to soothe a cough, heal the mucus immune barrier in the respiratory tracts, and also to prevent and treat bacterial and viral infections. There is even evidence that licorice root may be beneficial to those with COPD by slowing the progression of chronic bronchitis. 

Concerned about your lung health? Click here to consult with a functional medicine doctor.

Mullein

Mullein helps unblock the lungs by opening constricted airways, moistening the lungs, removing mucus, and lowering inflammation and irritation. Traditionally, mullein has been used for thousands of years to treat bronchitis, asthma, coughs, tuberculosis, and infections.

Slippery Elm Bark

Slippery elm contains something called mucilage, which coats the throat, and is another good demulcent. It is commonly used in natural lozenges to soothe a cough or sore throat. The mucilage in slippery elm traps and absorbs water, forming a gel-like substance which coats mucous membranes and can provide pain and irritation relief.

Thyme Herb

Thyme is antimicrobial and works particularly well for treating the throat and lungs. Thyme is used to fight respiratory infections, and treats a sore throat with its antiseptic properties and ability to dislodge mucus. Thyme is a go-to for coughs and nasal congestion.

Wild Cherry Bark

Wild cherry is anti-inflammatory with a mild sedative property which makes it useful for treating irritating coughs, like those that keep you up at night. 

More Tips for Health Lungs

Remember, preventative health is the key here. Herbal remedies work best when you are doing your best to live a healthy lifestyle in all aspects of your life. To set your lungs up for respiratory success, you will want to avoid drinking, smoking, toxic fragrances, and inflammatory foods. Get outside and breathe the fresh air, and partake in some sort of physical activity each day to keep your lungs healthy, clear, and strong!

Want to build up your immune system? Click here to consult with a functional medicine doctor.

References:

http://cancerpreventionresearch.aacrjournals.org/content/6/7/711?sid=179e57a9-3770-409d-84bc-cd83ef816963


The entire contents of this website are based upon the opinions of Dr. Justin Marchegiani unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Justin and his community. Dr. Justin encourages you to make your own health care decisions based upon your research and in partnership with a qualified healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Dr. Marchegiani’s products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products.