Symptoms and Dangers of Low Potassium

Symptoms and Dangers of Low Potassium

Do you know how much potassium you’re getting? I was looking at some recent research including a national survey which indicated that approximately 98% of Americans are not meeting the recommended potassium intake.

We all know the Standard American Diet is not good–but it’s not just the American diet that favors processed foods over whole plant foods, such as fruits, vegetables, beans, and nuts. This is the standard European diet. This is the standard Australian diet. Most developed first-world countries are primarily consuming processed, potassium-devoid food.

Let’s tie that directly into the research I mentioned at the beginning. A study done by a Chinese hospital and Chinese medical university in Wenzhou, Zhejiang Province, China on hypokalemia and clinical implications in patients with coronavirus. The researchers found that people that had severe hypokalemia–the technical term for potassium deficiency–and took potassium supplements were inclined to recovery. While the study results don’t directy say a potassium deficiency means you’ll get sick, it does indicate that because of the ACE-2 enzyme and the whole relationship to the virus, that one contributing factor may be low potassium levels.  And if you already have low potassium to begin with, then you may have a higher risk of fatality.

Click here for a consultation with a functional medicine doctor to learn about the symptoms of potassium deficiency!

Sodium and Potassium Pump

Why Does Potassium Matter?

Potassium is a key part of the sodium-potassium pump. A cell has sodium inside the cell and potassium outside of the cell, and the sodium-potassium pump uses active transport to move molecules from a high concentration to a low concentration by moving sodium ions out of and potassium ions into the cell

The enzyme that’s involved in making this happen is an ATP enzyme. You can identify enzymes because of the suffix “-ase” at the end: ATPase. ATP is important because it is the energy generated by your mitochondria.

Side effects of a potassium deficiency include:

  • Muscle or nerve problems
  • Mood issues
  • Adrenal dysfunction
  • Energy issues
  • Digestive issues
  • Heart palpitations
  • Achy muscles, muscle breakdown
  • Feeling tired and stiff
  • Tingling and numbness issues

Symptoms and Dangers of Low Potassium

One of the big side effects of a potassium deficiency is muscle or nerve issues, because potassium and sodium are very important for the muscles and nerves to work

There is also a potential for mood issues because sodium and potassium play an intricate role with the adrenal glands. Part of the reason why people’s potassium gets low–outside of a poor diet–is going to be because of adrenal function. Typically with the adrenals, aldosterone starts to go low.  Aldosterone is a mineralocorticoid that exists in the cortex of the adrenals. As aldosterone starts going low, sodium can start to drop too. As your sodium drops, sometimes your potassium can look like it’s not too bad. It can look actually a little bit high, but you could still actually have potassium issues because of the fact that your adrenals are weak and you’re peeing out a lot of your minerals. 

If you have sodium-potassium pump issues, you probably have energy issues too. Healthy mitochondrial function is needed to make ATP for the sodium-potassium pump to work.

Cramping is another potential side effect of being potassium-deficient, because the muscles need the fluid wiring, sodium and potassium, and minerals.

Your bowel movements and your motility starts becoming slower when your potassium drops. We need healthy levels of potassium so we have good bowel movements; otherwise there can be digestive and elimination problems.

Heart palpitations are another potential effect of low potassium, since we need potassium and magnesium for our heart to pump. Our heart is a muscle as well. So if your heart is skipping beats or beating harder or faster, that’s a sign of palpitations, which could be from low potassium.

And other symptoms include tingling, numbness, achy muscles, muscle breakdown, feeling tired and stiff. The breakdown of muscle is known as rhabdomyolysis and that breakdown is going to be very much helped with good potassium levels. You’re going to have less muscle breakdown with potassium levels being adequate.

If you have any symptoms of a potassium deficiency, please reach out to a qualified professional to test your levels and determine your next steps.

Root Cause of Mood Issues| Podcast #229

Anxiety, depression and mood swings are more than just that. Those things are real and are not just in our mind.

In this episode, learn various causes of our mood swings and situations that trigger it. Also, natural remedies to ease it and getting to its root cause is included in today’s podcast. Stay tuned!

Dr. Justin Marchegiani

Dr. Justin Marchegiani

In this episode, we cover:

01:03 Causes of Mood Swings

05:40 Medications and Antidepressants

10:12 Going Natural

11:07 Proper Oxygenation

26:29 Environment Matters

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Dr. Justin Marchegiani: Hey there it’s Dr. Justin Marchegiani. Welcome back to the podcast. We have Evan Brand here. Today we’re gonna do a live podcast today on mood and natural mood solutions, getting to the root cause of your mood concerns. So we’re live on Facebook here as well live on YouTube. Make sure you click down below, leave us some comments, we want to know what you think we appreciate a share we appreciate the like. Obviously subscribe and don’t forget to smash the bell so you can get notifications of our awesome content coming up. So, Evan how are we doing today man?

Evan Brand: Hey man I’m doing pretty good. I’m looking for statistics right now to make sure we can discuss how many people have depression how many people have anxiety. The Center for Disease Control they study this stuff and so I want to make sure people understand this, its not just

Dr. Justin Marchegiani: (Cross talking.) Exactly

Evan Brand: One or two people out in the world that are struggling with mood issues, I mean it’s an epidemic so how big of an epidemic well that’s what I’m about to tell you.

Dr. Justin Marchegiani: Awesome, so let’s dive in. So we’re gonna be talking about mood issues. Now I kind of draw the line in a couple different areas because there’s gonna be mood issues that are like all the time and you’re gonna see this in men women and more women. You’re gonna see mood issues that are more cyclical that are involved with their cycle whether it’s at typically it’s in the be, sometimes at ovulation and usually throughout that luteal phase, that last part of a woman’s cycle a week maybe three tool days to a week before they actually menstruate or bleed, have the period that’s when you’re gonna see a lot of mood issues and that could be hormonally based. So you have mood issues that are more cyclical than like an everyday kind of thing there’s that number two blood sugar issues people that are on a reactive hypoglycemia roller coaster and live their life on a blood sugar roller coaster that’s gonna be a problem. Number three, just poor nutrition. Like you’re not getting enough B vitamins and magnesium and amino acids in your body so you’re just – your diet’s just poor nutritionally it’s not nutritionally dense to provide the building blocks, to make all the brain chemicals, and then number four I would say is a malabsorption issue. Meaning, you don’t have the your digestion, is it off, or you don’t have the digestive secretions because of infection or food allergens or gut stress you’re not able to break down those nutrients so maybe the nutrients are coming in but we’re having a deficit on the breakdown side if you will

Evan Brand: Yeah, it’s not what you eat, it’s what do you digest from what you eat. So you could have a Paleo diet yes, but if you’re still on an acid blocker or you have some infection you could still be at a deficiency of those amino acids that you need to manufacture brain chemicals

Dr. Justin Marchegiani: Exactly, and then number five but kind of dovetail with the female hormone issue, but that’d be more on the adrenal stress side highs and lows in cortisol or cortisol rhythm issues. Now, I would say a lot of women that have the cyclical issues probably have an adrenal issue, but there are some people that may have all the time issues that are more Audrina based indoor men may have adrenal based issues, and then connecting to that, I would say with me the thyroid low thyroid hormone is commonly shows up as anxiety. They’ve done studies where they’ve taken people with anxiety and mood issues given one group, lithium the other group actual t3 and they found the actual t3 thyroid hormone saw some of the mood related issues and better than the lithium did. So those are kind of the big four or five things I’m trying to dovetail and we can connect any comments on that the brief over you Evan.

Evan Brand: Yeah, so what symptoms are we talking like when we say mood issues are we hitting, I mean we already did an anxiety podcast, we could talk about depression and that’s part of it are we just saying mood issues as a whole, I mean that could be irritability, that could be anger, I mean do we just tie it all together because really it’s all connected.

Dr. Justin Marchegiani: Yeah, your debility, anger, anxiety, depression and then typically those things tend to dovetail with fatigue I think the only if we’re unique most people that have fatigue tend to have those issues, with the exception of maybe anxiety. I’ve seen some people that are very energetic but are anxious kind of that tire but why are you kind of thing but they may not be like fatigue so to speak. So typically you’re gonna see almost all of those issues have a fatigue backbone with the exception of anxiety maybe but you can still be anxious and tired though –

Evan Brand: Yeah, so depression specifically what I found here for statistics in the US about 10% of the US population has reported depression, so I mean how many people are depressed that have not reported it probably a huge amount. So you know if we estimate the US population over 300 million people, 10%, that’s what 30 million people, yes a lot of people, so you know not just you and your brother and your sister and your cousin, no, I mean this is everywhere you go I think the numbers are probably way higher than 10%. I think it’s just that people are not reporting it you know, what are you gonna do like you’re gonna go to your doctor you’re depressed a lot of people are catching on to the fact that all they’re gonna do is get a prescription pad written form and in your intro you said nothing about a deficiency of depression medication, you didn’t say anything about a deficiency of anti-anxiety medication, so people know they know that’s the only supposed cure that they’re gonna get is those drugs and people don’t want to do, I mean you and I talk to people every single day all day and a lot of them do have depression and they know I can’t get help from conventional psychiatry or doctors so then they come to us because they know there’s something else going on it’s not just a pill that I’m missing to fix my depression it’s something underlying and I had depression for I don’t know 10 years I mean as long as I could remember and my mood started to lift significantly after I worked on my gut.

Dr. Justin Marchegiani: 100% now looking at a lot of medications acutely a medication may be necessary if you’re in a suicidal place that that may make sense but you have to work with someone to get to the root cause. The problem is most antidepressants that actually don’t work in the long run. What happens is the dose has to be raised up and then as you increase the dose your chance of side-effects increase and side-effects of antidepressants can be weight gain, it could be low libido, it could be other mood issues, it could be energy issue, so there’s other issues that could happen spinning off a various side effects. So like within the depressants we have SSRI medications right that’s your selective serotonin reuptake inhibitors, these are like your pre and post synaptic neuron you have all the the brain chemicals here in between the synapses is like your serotonin and there’s react ape ports on the presynaptic neuron where these chemicalsget recycled and a reuptake inhibitor it blocks this. So imagine putting my hand over this part and that way these chemicals cannot go back into that presynaptic neuron and if you guys are listening on podcast feel free and click below to see the YouTube links that you can see my, my little hand puppetry if you will. So that’s kind of SSRI you have SSNRI which is like Selective’s Norepinephrine Reuptake Inhibitor so SNRI. Now, looking at norepinephrine dopamine which is similar you have things like wellbutrin, there’s other medications that are in that category that are working more on adrenaline dopamine kind of cascade because dopamine’s a precursor to adrenaline. So you have those medications on the depression side there’s new lines of antidepressant medications coming out working on brain inflammation. The conventional medicine is starting to understand that brain inflammation is a big impact on mood so they’re giving you these medications to help with that. Now, you got to be careful because anytime you don’t get to the root cause you create potential side effects, so these medications are so new coming out not even sure if they’re even from market yet they’re in the testing process now, so the side effects I’m not sure of yet but I guarantee you there’ll be a whole bunch. Now, looking at functional medicine in nutrition we want to get to the root cause of that brain inflammation, so one of the first thing we look at is to diet and the first thing after that is the gut because inflammation in the gut drastically causes inflammation in the brain, we have this the tight junctions open up this leaky gut gastro intestinal permeability phenomenon occurs undigested particulate bacteria foods gluten dairy get into the bloodstream, they can make their way up to the brain and make an activate our microglial cells which can create more cognitive issues more brain fog and more mood issues. So depression is a really big component so just kind of laying out the medication here and then obviously we have like our our gaba like as a pain medications which are gonna be working more on the gaba receptor sites and then we have ourold tricyclic s–from the 80s which are antidepressants from the 80s, less side effects with those but those still are kind of a weaker SSRI and —

Evan Brand: Well the problem with the benzos is that they’re highly addictive and if you try to come off of those you have a big withdrawal period where there’s going to be potentially more anxiety, more depression, panic attacks, I mean I’ve had people who come to me after they tried to go cold turkey off of a benzo and they’re having night sweats and panic attacks it’s like no you can’t do that, you know those drugs were really really effective so it’s just not something you can do on your own, you really have to have a doctor to help get you off of those drugs and a big problem is two people that are trying to mix supplements with medications – I mean you can’t just go take a SSRI and then go take 500 milligrams of 5-htp that’s just not something that you want to do it’s rare and I haven’t seen any cases of it personally but it’s called serotonin syndrome and that’s when you can boost up serotonin way too much with the drug and a nutrient so this isn’t. I mean when you’re talking brain chemistry you don’t want to come in there and just go to Whole Foods, buy a bunch of amino acids and start popping them if you don’t know what you’re doing

Dr. Justin Marchegiani: Yeah, and the side effects are pretty prolific like we talked about nausea, fatigue, poor sleep, dry mouth, blurred vision, constipation, low libido, weight gain, so all of these things can, can add to the milieu of symptoms that are already there and we’re not getting to the root cause, so we kind of lead it the medications we talked about how important that is we obviously know foods really important because foods where all the building blocks come from so we want diets a very important very nutrient-dense with lots of good healthy B vitamins especially b6 which helps activate a lot of our brain chemicals. So obviously like a paleo temple it’s gonna be a great starting point with healthy organic green vegetables you know lower sugar fruit lots of good anti-inflammatory compounds they’re good healthy omega-3 fats which can help a brain inflammation and help with inflammation in general and lots of healthy good animal products that are gonna be grass-fed not grain fed with all the roundup and pesticides and junk.

Evan Brand: Yeah. I’ve noticed a big difference myself with the fish oil just taking that tends to just level my mood out it’s not like it’s an any depressant effect like you would get from something like rhodiola, that’s one of my favourite adaptogenic herbs for depression. It’s not that significant but it just kind of makes you more even keel, where something like an adaptogen is going to help really boost you and you’re gonna feel altered, almost like you have a buzz from the herbs like, whoa I’m I feel happy I feel great. Yeah ___[10:57] is good for that gotu kola is good. I would say ginkgo could be in that category too because ginkgo will help with the blood flow in the brain, you know some of it could just be poor oxygenation what you think like if someone’s sedentary and maybe they have poor circulation, maybe they have mold issues that’s blocking nitric oxide, I mean how much of depression do you think is an oxygen related issue.

Dr. Justin Marchegiani: Yeah, I mean anytime you have poor or increased coagulation meaning blood is kind of viscous, it’s like molasses things aren’t flowing well. Exercise helps improve that just getting inflammation down when you’re more inflamed and you have more inflammatory cytokines or interleukins in your bloodstream. Things get stickier and they’re not gonna flow as well, so movement helps getting the inflammation down, helps doing things like ginger tea. Ginger can be helpful. Fish oil is a natural blood thinner so you talk about fish oil. Part of the mechanism on fish oil works is it helps that coagula, it prevents things from clotting and sticking and also a fish oil is like a weak MAO inhibitor so basically, MAO is another kind of enzyme that metabolizes a lot of these brain chemicals kind of naturally and this it has a way of delaying that metabolism so not quite a drug like effect but it does have a mild effect there and again when you do things that are more natural and have mild effects. You have less side effects so fish oil’s wonderful with that also things like St. John’s Wort has some really good depression antidepressant qualities too and a lot of times they’re working on indirectly. They have anti-inflammatory effects they have which then helps with blood flow which then they tend to have maybe a mild MAO kind of you know decreasing the metabolism of our brain chemicals kind of mechanism that’s happening at play. Also one thing about gluten they’ve done, studies on gluten where gluten decreases blood flow to the frontal cortex so oh you have you know your garden hoses up the side of your head is called your carotid they gave people basically functional MRIs and they looked at blood flow and activation and the frontal cortex pre and post gluten and they saw significant reduction in blood flow to the frontal cortex the neocortex which is what makes us humans compared to animals and they saw a significant reduction and also significant reduction in migraines when that blood flow was supported. Meaning, when they cut the gluten down migraine stopped and they also saw that the blood flow was coming up when that happened so kind of outlined the mechanism. Blood flow is a really important component so anytime we can decrease the coagulate, meaning things sticking and we can improve the blood flow, like we talked about that makes a huge difference now exercise helps with the blood flow it also helps stimulate beta endorphin which is the natural antidepressant. It hits that opiate receptor and it’s a nineteen amino acid compound, meaning you need to be digesting and having good protein so the more you’re vegan and vegetarian and you’re not getting good quality proteins in there or you’re not supplementing additional proteins and b12 as a vegetarian vegan in omega-3 from algae you’re in a worse situation because you’re not getting those certain nutrients in

Evan Brand: Yeah, I’ve got my wife on some herbs right now St. John’s Wort passion flower motherwort dandelion Damiana black cohosh this is a kind of a postpartum mood remedy that we’re using that’s an herbal tincture and I’ve tried it and I feel great. I feel a lift from it too. So, this is something we’re doing for her just because you know a lot of depression we didn’t talk about this yet, a lot of depression is postpartum but then it never lifts right you and I talk with moms every single week. We’ll talk with the mom who says you know you and I will do a history together we’ll say okay let’s go back in time when did this depression start or when did this anxiety start. We’re always trying to make our timeline and so a lot of moms will say, wow this was after my first kid or after my second kid or after my third kid, the depression came on and it never went away and some of that steroid related because we do see a lot of postpartum Hashimoto’s where all the sudden the immune system goes crazy antibodies go up. The thyroid gets attacked the woman becomes hypo under functioning with thyroid or maybe she’s alternating between hypo and hyper and then she’s feeling bad because of that and so these herbs can come in and really help to regulate not only thyroid function, you could do some adaptogens to help adrenal thyroid but then the mood ones too like passion flower. I love it you know I think it’s something everybody could benefit from especially if you’re more on the anxious side where you’re stuck in traffic and you’re freaking out even my grandfather the other day he told me he said, Evan I can’t handle traffic anymore, and my grandma starts making fun of them they were talking about how they got stuck in rush-hour traffic and my grandpa was kind of freaking out kind of panicking getting anxious and he never used to be like that. So I told him, hey maybe we can get you a passionflower tincture. You put it in your purse, you know my grandma’s purse and take a shot of that next time you get stuck in traffic

Dr. Justin Marchegiani: Exactly, now some natural ways that you can improve GABA levels is there’s some people to talk about GABA is too small or too large to pass the blood-brain barrier, but yeah I don’t know I kind of go back and forth on that so there’s that so you could take a product called Pharma GABA and you can do with sublingually so I’m gonna take one now to kind of promote my parasympathetic nervous system responses.

Evan Brand: I love them. They’re great. I chew them up too so great, great tasting.

Dr. Justin Marchegiani: Anytime you’re supporting adrenal stress right because GABA is the brake on the sympathetic fight-or-flight nervous system so anytime you can kind of bring cortisol and adrenaline back into balance, it’s helpful so things that you can do are gonna be ___[16:37] is gonna be excellent, magnesium will be excellent, ashwagandha will be excellent as well that really helps curtail, let’s just say a lot of the at the HPA access dysfunction.

Evan Brand: Let’s go into magnesium a bit because you hit that one but I don’t want to gloss over because magnesium is a huge needle mover. Maybe let’s dive into just a couple different forms for people that they could use. So last night I did some magnesium oil. I did some spray on my legs, my calves, I started to feel a little cramp coming on I thought you know, I was in the sauna over the weekend I was sweating I might not have replenished enough of my magnesium so I did magnesium oil and I slept much better with the oil. So that’s one topical form and then a lot of times you and I talked about magnesium glycinate, ___[17:23]I’ve had really good success with ___[17:25] especially for like muscle relaxation.

Dr. Justin Marchegiani: Exactly, so magnesium is gonna be excellent. It’s a natural beta blocker so it can relax your heart so your heart’s not beating out of your chest. Obviously there’s like a thousand enzymatic roles in the body from magnesium so it’s in help with motility it’s in help but blood sugar metabolism it’s in hell but inflammation in the brain I think part of the mechanism and how magnesium works , ___[17:51] it’s highly anti-inflammatory to the brain. I saw a lecture with Russel Blaylock who’s a famous neurosurgeon and he said clinically when he operated on people and he would give them post-op stuck the metal magnesium they heal better than his colleagues patients that had the same procedure, it was like a remarkable difference. He said so supplementing additional magnesium really made a big difference.

Evan Brand: Magnesium threonate, that’s amazing magnesium threonate would be the other form I would recommend just because we do know magnesium threonate and a-actually crosses the blood-brain barrier so when you’re talking about gaba, you know supposedly being too big to cross the blood-brain barrier and the pharma gaba is smaller and is more easily readily available to get through the barrier same thing with magnesium threonate. So yeah if you do one to two grams of threonate that’s going to get to the brain and you’ll feel significant changes, I mean we’ve used it for people with PTSD. You know some of the literature we use professional healthcare companies to manufacture our products and they’ll give us some text sheets on the back end and they’ll have a whole list of symptoms why you would use threonate and PTSD and anxiety is one of them so we know these people think of anybody who’s at a stressful or traumatic event which is pretty much every human ever obviously some more than others. The threonate to me is a good a good remedy I mean if I had like a a trauma clinic or like a PTSD clinic or something or a mental health clinic where you know let’s say you’ve got people having mental breakdowns, you know kind of back in the day like my grandmother her grandmother would talk about oh if you have a mental breakdown you go to this hospital you stay in there for a month and they send you home. I guarantee they weren’t using magnesium threonate because it wasn’t invented back then but that would be something I would have in the protocol for people rather than, yeah, automatically going to the prescriptions.

Dr. Justin Marchegiani: Yeah, I know Blaylock. I don’t even think Blaylock was using threonate, back things it wasn’t really that big.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Using a standard citrate, probably citrate it’s fine. It’s a cheaper version you can get it in natural calm, it can cause bowel, your bowels to move so some people do better with the ___[19:51]  or a or glycinate or if you know this cognitive issues we can do a magnesium that is a threonate, that better at crossing the blood-brain barrier we love that.

Evan Brand: Yes, I wanted to give you a brief diversion on the magnesium piece because here magnesium, but then they don’t know there’s a lot of different varieties of it that have different effects .

Dr. Justin Marchegiani: Mm-hmm yeah, exactly. Now, next passionflower is great which is otherwise known as melissa officinalis. Another great relaxing kind of herb. It tends to be almost like a natural.

Evan Brand: melissa is a lemon balm.

Dr. Justin Marchegiani: Yeah, oh yeah I’m sorry yeah yeah, the same thing Melissa and lemon balm tend to be relaxing so a lot of like natural hyperthyroid formulas have that in it so Melissa Melissa and lemon balm are over here passion flowers is similar and then Valerians both sent when they didn’t have relaxing kind of dampening effects and yeah, thank you.

Evan Brand: Yeah theLlatin on because you said passion flower, then you said otherwise Melissa yeah ,passion flowers Latin name is like Pasi flora something and carnie incarnate, uh, something like that I don’t really.

Dr. Justin Marchegiani: It’s, it’s lemon balm and Melissa are the same thing yeah, flour and then valerian excellent also we can add kava to the mix there’s been research on kava from the Cochrane Database. You know, finding it’s very effective at helping with anxiety without the side effects so kava is excellent.

Evan Brand: Have you tried kava?

Dr. Justin Marchegiani: I’ve tried it supplementally a couple times. I’ve tried it, someone made me kava tea before, it’s big in Fiji I think it’s very helpful it basically activates those GABA-A receptors is GABA-A and GABA-B and it really activates the A receptors in the brain so it can really help kind of chill you out and relax you.

Evan Brand: I went-I’m going to a kava bar one time when I was down in Austin and drink a shot of it, it tasted like – it tasted and looked like mud water.

Dr. Justin Marchegiani: That’s exactly how it tasted look, yeah.

Evan Brand: And I was I was altered, I thought man I don’t know if I’m gonna be able to drive home. I mean I’m really sensitive so maybe my GABA system just got flooded but I was sitting back in the chair kind of like, whoa I mean it hit me like a ton of bricks.

Dr. Justin Marchegiani: I’ve also seen CBD do very well in the mood side too so that’s ___[22:01]  with the non active THC has, I think is very helpful too I always tend to lean more on nutrition first, so like the B vitamins, b6, magnesium ,will also do higher dose l-theanine amino acid which can help promote GABA production stuff the mental gammas I tend to promote those along with the long-standing adaptogens that have a long term success record, like ashwagandha is excellence I’d say Kava after that’s wonderful lots of studies on it and then- um-any comments on that before we go to the next step?

Evan Brand: Yeah CBD has been helpful for me too. I give it to my daughter so if she complains of a headache or a bellyache or if she seems restless at night we’ll just give her a one milliliter dose which the brand I carry is a 10 milligram CBD, she’ll go right to sleep so it’s a really good settling thing and so for kids too. I mean I didn’t mention the statistics I was looking at some of this stuff from the Center for Disease Control. I mean we’re seeing we’re seeing 20 to 30 percent of children now are reporting anxiety and depression so I have moms that are telling me their kids are suicidal at 5 10 years old. I mean, when I was 5 and 10 years old I had no comprehension of death or mortality so I don’t know if it’s you know the the TV shows and the violence that kids are exposed to in other places that I wasn’t because I was outside on my bike all the time or what but you know as a kid I don’t remember other kids being anxious and depressed. Now I mean it’s almost every single kid that I see there’s an underlying anxiety problem associated with as you mentioned the gut you know we see these kids eating conventional food or get tons of glyphosate they’re good bacteria killed off the bacterial overgrowth are making toxins which are depressing and causing anxiety and the kids, so I mean there is a root cause for the kids too. It’s not where they need to be put on medication immediately same thing with ADHD. ou know these kids are getting diagnosed with ADHD we see that get better with fixing the gut to 100% and there’s herbs for kids too so there’s actually I mean, technically we can just dose adult formulas down but there are some special kids formulas that we do use that are specifically maybe they have a glycerine base as opposed to an alcohol base and passionflower skullcap, things like that you can use those with kids as well.

Dr. Justin Marchegiani: 100% also there’s something called people, may know it call phenibut or for amino 3 phenol butyric acid. Now this components a little bit controversial because there’s, there can be some addictive qualities to it it’s essentially a GABA agonist. Supposedly crosses the blood-brain better it’s a GABA agonist I’ve had some people that had phenomenal results with it ,but I’ve seen it I’ve seen it become a little bit more addictive and people become dependent upon it so it’s one of those things as a double-edged sword. I would never go to it first but I’ve seen people that have done very well with it I think it would probably be better than peeing on a benzo long term but I would always try that, that mean the last thing I would potentially ever go to in my arsenal because of so the so-called some addictive qualities to it

Evan Brand: Yeah, I mean it helped, it helped change my change my life and get me through some tough times but, yeah, there’s a huge risk with people not respecting it and overusing it and down regulating GABA so much that you get more anxious you get more panic etc. When you try to get off of it whereas the pharma GABA that you just chewed up you’re not gonna have that potential for that one.

Dr. Justin Marchegiani: Exactly, yeah, exactly, so we have a lot of the supplementation I would also say if it just depends – because if we have a high cortisol state things that can help lower cortisol make a big difference. Some people have a very low cortisol state and some of their anxiety and mood issues is driven by low cortisol so some people think it’s like, hey this is the solution for that, well it really depends because what if you have low adrenaline and low cortisol well a lot of your anxiety and mood stuff could be from the lower state versus higher anxiety and high cortisol or higher adrenaline and high cortisol be many things to bring it down so we may be doing things more like phosphorylated serine to bring it down and actual gana we may do things to bring it up that are more stimulating like ginseng or licorice if it’s chronically low, and or tyrosine if we see low adrenaline so we got a look at what the pattern is because sometimes extreme high and lows can feel the same and that’s hard people to wrap their heads around.

Evan Brand: Yeah that’s a good point. I mean I had a woman in college who she, she was in Hawaii I remember that we found out her her dorm was super moldy and that’s why she was having all these panic attacks so that was cool too, but she had extremely, extremely high cortisol but just based on doing the initial intake and we talked over her symptoms. She was exhausted couldn’t get out of bed etc, we thought, oh my god I bet her cortisol has flatlined, no it was the opposite it was very sky-high so this is why you know you listen to a podcast you think, oh I’ve got low cortisol I’m tired I’m gonna go take a bunch of licorice, no way if we would have given that to that girl with high cortisol we would have made her blood pressure go up she would have had more anxiety more panic so this is why you have to test you don’t want to guess with this stuff you really want to get the data, maybe we should talk about that now do you think we should move on to testing.

Dr. Justin Marchegiani: Yeah so I would say off the bat right we got to make sure the guts functioning well right the absorption of these nutrition where inflammation kind of gets into the bloodstream and goes to the brain really depends a lot on gut inflammation so good high-quality stool testing. I know we talked about doing the GI map task we like there’s a couple others that we do as well but if someone wants to dig in deeper to the gut we have to really fully assess that.

Evan Brand: Yeah so the guts huge urine I mean you’re in great we test for micro toxins through urine we test for chemicals we test for amino acid metabolism we test for bacterial overgrowth and Candida which can affect the mood so getting a urine test will be key and then getting the saliva adrenal test or a urine I don’t know do you do salivary adrenals anymore are you just doing urine

Dr. Justin Marchegiani: I know sometimes salivary adrenals but I’ve been liking the urinary metabolites because I see a lot of women that have a hard time metabolizing estrogen, so it’s nice to be able to run that one because I can also see how they’re metabolizing the hormones too. So that totally helps if you’re a female and you have estrogen dominant issues. So I maintain a new right estrogen dominance right that that ratio of progesterone estrogen drops right progesterone and estrogen drop like this. Meaning everything drops but progesterone drops faster so it’s nice to be able to see that because that can be a big mood issue – remember progesterone is a natural GABA chloride channel opener meaning we can promote GABA in the brain with healthy levels of progesterone so part of your GABA issue could be lower progesterone as a woman and also progesterone is very anti-inflammatory in the brain even with men with like concussions or any brain trauma they’ll give a couple hundred milligrams of progesterone for a few days after brain trauma to actually curtail the inflammation in the brain, so progesterone is very anti-inflammatory because of its cortisol building block effects of progesterone can help brain inflammation in brain trauma.

Evan Brand: Now let’s go a little further then are you talking supplementing progesterone, are you taking, doing some of these specialized maca extracts to help regulate progesterone estrogen?

Dr. Justin Marchegiani: Both no, but it depends on how bad it is. If it’s slightly out of balance we always lean to herbs and diet and natural components, if it’s significantly out of balance will use the bioidentical plant base and we’ll dosed it accordingly to accelerate the results.

Evan Brand: Okay and then like estrogen dominance, you’re talking removing plastics removing phthalates and other things from the makeup and environment. Plus maybe you’re gonna be throwing in some herbs to help regulate that maybe like the do you pronounce it ___[29:41]  

Dr. Justin Marchegiani: Yeah ___[29:42]  more gonna help on the testosterone side, but on the inside we would do more like calcium to ___[29:47]  and all methane, fiber. Right these things are really helpful also there’s some some seed protocols where they’ll, do they’ll, do what’s the seed-

Evan Brand: Alpha linoleic acid omega-3 flax

Dr. Justin Marchegiani: Yeah exceed in the first half of the cycle so f for first half of the cycle and then typically a lot of sesame seeds for the second half of the cycle F &S; sometimes they’ll throw some pumpkin seed in there as well and that can help bind up some of the estrogen metabolites too.

Evan Brand: Oh interesting I was going to say I was reading some studies over the weekend about detoxing mycotoxins and actually one of the suggest that things to do was take flaxseed to help bind to toxins so that’s pretty cool it’ll bind the excess estrogen as well.

Dr. Justin Marchegiani: Yeah I think that’s in our ___[30:36] buying product too isn’t it?

Evan Brand: Yes,

Dr. Justin Marchegiani: Exactly, so that’s really good for mycotoxins and mold and then we already kind of dovetail through the mold mycotoxin coagulate issue it’s in a decreased blood flow so if you have any mold or environmental stuff that could easily be affecting how the blood is flowing to the brain and obviously potentially even getting to the brain and activating those microglial cells – that’s very possible.

Evan Brand: Yeah I’ve got a story people like stories right so we get into the geekiest and then people like zone out on us so here’s a here’s a quick stor.y I was working with a teacher last week she’s in her sixties she’s about to retire and we were discussing her urine test we looked at her urine for mycotoxin. She had a lot of different mold problems and I gave her some of these little plates these little petri dishes and we took him to her school she put him in her classroom. Her classroom came back very moldy and she goes, oh my god. you know this explains why after summer break you know all the teachers leave they come back and she says her and all of her colleagues talk about how they get depressed they get fat they get tired they get anxious etc, when they come back to school. Now obviously people would say, oh it’s just the kids stressing them out, no it’s she’s getting out of the moldy environment. For the summer the mold grows there in the summer they probably don’t run the air conditioners because they’re saving money on budget. during the summer they come back school starts in August or whenever and then they get sick again but luckily in her case she’s retiring so it didn’t matter but this is a real issue with a lot of women in office buildings or school buildings if you, if you feel worse, if you feel more tired, you feel more depressed etc when you go into a certain environment that might not just be the stress of the job or the bad boss this could be a toxin or pollutant in there so you may need to get like a HEPA filter in your classroom or a portable HEPA filter to put on your desk. if you’re in a cubicle and you’ve got people wearing perfume and stuff around you right you may need to try to make yourself have a little healthy bubble if you can’t leave or fix the environment that you have to work in.

Dr. Justin Marchegiani: 100% also be on top of your environment, so we’ve already done plate testing in your house, in my house, my basement, my new office. And my basement tested great for mold but I’m noticing that the humidity contents going up as we get closer to the summer so like my first two floors it’s like 43 44 % but then my basement where my office is is that 56%. Now the problem is I would run the air conditioning more to knock it down but the problem is it’s already sixty five degrees right now it’s already kind of cool because of you know the nature of basement so because of that because I’m on top of it I’m gonna be getting a whole house dehumidifier. Specific for basement dwellings to remove the humidity from the air that way I don’t have to drop the temperature I can keep the temperature where it’s at and just suck the moisture out of the air and drain it out so based on your feedback, I’m already on top of that and everyone listening, if you have if you have a moldy environment or any environmental symptoms but there are no leaks check the humidity content of your house.

Evan Brand: Yeah it sounds like we’re coming out of left field, like okay we’re talking about GABA supplements now we’re talking about your environment. Your environment it’s a huge piece of I mean, think of how much time you spend indoors, it’s like what ninety five percent of your day. Most people are indoors so the air you breathe can affect your nervous system we know just based on looking at the EPA’s work where they’re sampling the homes that live near highways we know that the pollution from a major highway gets into the home and that actually increases cortisol so you actually have a shorter life span if you live close to a major highway or a busy road or a busy intersection they’ve done. Studies on people that live near four-way stop signs and four-way traffic lights and if you live near those busy intersections the cars are breaking the brake dust gets into the air it goes into your home it contaminates you know your children’s lungs your lungs etc so if you’re in a busy area and even if you’re not in a busier. I mean, here’s the deal, you know I’ve got five acres, I’m out in the country but we still have bad air quality because of the way the wind blows and so when the summer starts heating up the pollutants from the car exhaust will have air quality alert days all the time during the summer so that’s the time where you want air purifiers in your home, in your space. Making sure your airs clean now if you go outside and play sure you’re going to get exposed to the crap, but if you’re in your home you need it to be a sanctuary in terms of free of extra EMF free of mold free of extra humidity free of pollutants you know this is very, very critical especially your bedroom.

Dr. Justin Marchegiani: 100% that’s why we recommend also high quality air filtration as well if you go to my site justinhealth.com/ shop, you can click on the recommended products tab and look at some of the products that I recommend, that I personally havem I have multiple same thing. If you go to evanbrand.com and click on his store button, he has similar products that we both recommend and talk about and share with each other but if you guys are enjoying this cause and that’s a great way to support us so you can get great products we’ve already tested for y’all.

Evan Brand: Yep, yeah we’ve got like four different brain. I’m always experimenting so we’re trying to get you the best of the best. There’s a lot of crap out there like if you go to Target or Walmart and you go buy a air purifiers thats better than nothing, yes, but is it the best of the best? Probably not, no.

Dr. Justin Marchegiani: Exactly.

Evan Brand: You get what I pay for you, get what you pay for. You can go buy a $50 HEPA filte.r but you know, I buy more like $500 HEPA filters but they’re you know they’re built like a tank and they’re quality so-

Dr. Justin Marchegiani:  Yeah it’s kind of we are getting like almost a surgical base kind of air filtration.

Evan Brand: Yeah it’s like a hospital in my house in terms of the, the air purity not the not the Candida everywhere on the walls that is affecting people. Have you read about that the candida like ___[36:06] outbreak? It’s very dangerous.

Yes, yes I’ve seen that it’s pretty bad.

Evan Brand:Hhospitals don’t know what to do. I mean they’re, they’re running out of options, you know the antifungal drugs are not working.

Dr. Justin Marchegiani:  Yeah they need to be using more silver and probably even more specific probiotics because I think a lot of these Candida things are coming potentially from people post antibiotic supplementation or post probiotic prescription so I think the components big also, I know surgically my mom’s a surgical nurse for 45 years they’re using a lot more silver, now they’re wrapping all joints in like a silver cellophane after surgery to prevent MRSA an issue, so silver is already being used at that surgical level.

Evan Brand: Good, good yeah we still need more help though, I mean when the center Disease Control says, hey basically don’t even go in a hospital unless you have to, I mean, that’s pretty scary.

Dr. Justin Marchegiani:  Oh yeah like if I have to go somewhere, I’m, I’m calling a doctor and going directly in paying cash or I’m going to an urgent care place where you’re kind of in and out versus the conventional ER forget about.

Evan Brand: It, it’s just not it’s just not safe so you know obviously the, the hospitals are there sometimes we have to go there but when we’re talking about mood related issues. I mean you could have something as simple as a panic attack, you think you’re dying because if a panic attack you go to the ER and then they go run a bunch of tests on you and send you home with anxiety prescription and nothing was wrong and now you expose yourself to all these pathogens in the hospital and you come home more sick than you went in that’s just not a good thing to do.

Dr. Justin Marchegiani:  Exactly, yeah, 100% same, and today was a great podcast, is there anything else you want to, to the show here?

Evan Brand: The last thing blood sugar. We’ve done so many we always talk about blood sugar but I just forgot to mention it because when we talking anxiety, mood issues there’s so many pieces of the puzzle when I feel low, if I feel depressed, if I feel anxious, if I feel like oh my heart’s starting to race a little bit, I’ll go prick my finger and sometimes I’m at – at like a 68 on my alt my glucose. Is just too low I’m getting that adrenaline response which is driving anxiety so I mean, don’t you know we got so many people practicing intermittent fasting and doing low carb diets etc, and these people depending on the, the stress and their life they may be less tolerable of lower carb less tolerable of intermittent fasting meaning a intermittent fasting was too stressful so I just currently don’t do it and I was noticing that I felt more anxious on those fasts and so for me blood sugar stability is a huge component.

Dr. Justin Marchegiani:   Yep I 100% agree and if you guys are liking this content give us the thumbs up, smash that like button and hit the bell as well so you can get notifications. I’ll be doing a live thyroid reset summit QA for all the people that were involved in the thyroid summit so if you guys are enjoying this I am set to go live here another 40 minutes we’ll be taking only thyroid Q&A; topics anyone listening to this as well head over to thyroid reset. Some of oumake sure you subscribe there as well. Evan, anything else?

Evan Brand: Our plugs people have these issues every day all day these are things we work with every day all day ,so if you want help from Justin please reach out to his website justinhealth.com you can schedule a call from around the world. For me my site is evanbrand.com. We don’t care who you work with as long as you get the help you need we’re just happy to be, a be of service to you guys.

Dr. Justin Marchegiani:  Yeah 99.9% of people that we help be never either me cuz they get access to our free content and they start utilizing it and then some need you know deeper more hand-holding and deeper assessment so that’s why we’re here and glad that everyone is enjoying the podcast and we’ll be back. Evan take care

Evan Brand: You too, take care bye

Dr. Justin Marchegiani:  Take care, bye.


References:

https://www.evanbrand.com/

https://justinhealth.com/

https://www.youtube.com/watch?v=wqKqHwkdOpc

Overcoming Anxiety Naturally | Podcast #226

Surges of cortisol and adrenaline makes one emotionally stressed. They are gonna shut good blood flow to the body, especially to the brain, thus, causing stress. One bad result of it is the inability of the brain to make good decisions. What’s in it for anxiety? Find out more!

Today’s episode talks about mold and environmental stressors which creates histamine responses, creating mood issues, and ultimately, anxiety. Listen as Dr. J and Evan Brand discuss the important points to address these issues in a natural and functional medicine perspective. Continue for more! Stay tuned.

Dr. Justin Marchegiani

Dr. Justin Marchegiani

In this episode, we cover:

00:40    Mold Issues, Blood Sugar and Anxiety

07:22    Fructose

09:45    Emotional Stress

12:22    Fatty Acids

14:14    Going Organic

26:24    Blood Sugar Level Optimization

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Dr. Justin Marchegiani: Hey Evan, it’s Dr. J here in the house, how are you doing today?

Evan Brand: Hey man, good morning! We’re- we’re a bright and early today for this.

Dr. Justin Marchegiani: Yeah, we’re trying to get our podcast in earlier just to free at time in our schedules to get other things done, so I think it’s great. We’re gonna be trying to be uh chatting weekly at 8:AM CST, 9:00 AM Eastern Time. So I’m really excited to be here with you, it’s a phenomenal weekend, the weather- it’s this time of year it’s just absolutely amazing. How is it where you’re at?

Evan Brand: Oh, man, it’s been magical too, it rained for like 48 hours straight, and then, all the sudden, the clouds break up and the sun comes out and the birds are singing and the grass is green and it’s growing so fast now, so, I can’t complain.

Dr. Justin Marchegiani: That’s great man, excellent. Well today we talk about in our pre-show, we were texting yesterday or the weekend about doing a podcast on anxiety, and I think we can- we can just dive right in. So, off the bat, when it comes to anxiety, let’s just kinda touch upon your personal issue with the mold. So we’ve talked about mold and environmental stressors, potentially creating histamine responses, and then creating mood issues. Why don’t we go into your experience with the mold that the mycotoxins and your anxiety?

Evan Brand: Yeah, I- I had for the last 6 months to a year, I’ve had random little spurts where I was having heart palpitations, and some of that was related to my cavitations. I did that podcast with Dr. Stewart Nunnally my surgeon-

Dr. Justin Marchegiani: Yes.

Evan Brand: -who cut me open and cleaned out-

Dr. Justin Marchegiani: Yeah.

Evan Brand: -all my 8 cavitations, but that was a huge source of heart palpitations. But after the heart palpitations disappeared, I still had some anxiety. I’d have these random blood pressure spikes, and I’d hit you up, and say, “Dude, what’s going on, my blood pressure, I don’t know”, and now I figured it out. It’s related to mycotoxins because what mold does when you’re exposed, if you’re living in a moldy house or uh apartment, or a condo, or you work in a moldy office, or you’re a librarian, and you’re working around moldy books, mycotoxins prevent nitric oxide production from working properly, and you need nitric oxide to help with your vasodilation. And so, you basically have a constriction of everything which is why my hands and feet have been so cold too is because, nitric oxide is getting blocked by mycotoxins, and so, when I take my detox supplements, whether it’s binders, or supplements like chlorella, I noticed my hands and my feet will warm up and then all the sudden, I’ll feel better, I’ll get more energy, my anxiety just disappears. So I can’t say that this is the only trigger. We do wanna talk about blood sugar and some of the diet pieces too. But I’ll tell you just personal-

Dr. Justin Marchegiani: Yes.

Evan Brand: -experience, I’ve had all the adrenal stuff dialed in. I’ve had all the blood sugar stuff dialed in, and I still had anxiety issues, and it was all tied into mycotoxins.

Dr. Justin Marchegiani: But it was better than if you didn’t have the- that stuff dialed in.

Evan Brand: Oh, yeah, if I- I mean, if I- if I was not taking daily adrenal supplements, and if I were skipping meals, or not eating enough fat, I would probably be a wreck.

Dr. Justin Marchegiani: Yeah, we kinda look at your history like these problems like, you have problems in the past, right, before you kinda got into this field. You had that dialed in, you were better, and then along came the mold mycotoxins stress years later, and then that kinda brought things back to a head again, is that true?

Evan Brand: It is, yeah, ’cause, when I was living in Austin and I was packing up-

Dr. Justin Marchegiani: Yeah.

Evan Brand: -moving back to Kentucky, I mean, we’re calling you like dude, “I’m having a anxiety attack, I can’t control it”, that was all adrenals.

Dr. Justin Marchegiani: Yeah.

Evan Brand: I mean, I was- I was literally working with clients on top of a cardboard box with my laptop, ready to pack up and drive 2000 miles across country. So that was more situational anxiety.

Dr. Justin Marchegiani: I remember that too, there was a lot of blood sugar issues too, I think you are going like 8 hours without eating, and I think we made a couple of blood sugar tweaks that helped a lot.

Evan Brand: Yeah, I was probably going like maybe 5 hours which is just too much for me. Now I can’t do that anymore. And so-

Dr. Justin Marchegiani: Also to remember the end of your day, I think there was just a big gap between when you had dinner when you went to bed. I think you were like eating at 5:00PM, going to bed like at 10:00 and then like not having your breakfast until like 10:00AM the next day.

Evan Brand: Yeah, it was a long time, and I was like 5 hours.

Dr. Justin Marchegiani: You was like a 15, 16-hour gap. But you know, that kinda like an intermittent fasting kind of gap but, for some people, that could be a little bit of a blood sugar stressor because when we go and utilize gluconeogenesis, that’s cortisol dependent. We will forget the gluconeogenesis which is fine, it’s normal, but it’s cortisol dependent. And we don’t quite have enough cortisol or adrenals or a little bit taxed, we may not be able to enter into those processes, uhm, optimally. So that’s something that the he’s mind.

Evan Brand: And I did not have enough cortisol, I did my salivary adrenal-

Dr. Justin Marchegiani: Yes, I remember that, it was low.

Evan Brand: -it was very low. It wasn’t like completely burned out, I wouldn’t call it adrenal fatigue, but I was at the bottom end of the barrel there without being under the low end of the reference range. My cortisol sum was maybe like a 12, anything below a 10 is terrible and I was like a 12. So I was barely hanging in there with adrenals.

Dr. Justin Marchegiani: Exactly. So, kinda key things to think about, I want people listening to- to think about the underlying mechanism. What’s the mechanism of why you’re feeling the way you’re feeling? This is important because a lot of times, when you’re going to the conventional doctor, really, the underlying mechanism is not addressed. Typically, there’s the genetic predisposition, genetics like victimization-type of mindset where like we don’t know what it is, err- here the- here’s this drug. So people don’t really connect the dots to the cause, right? So we’re tryna trace everything upstream to the cause. So, if we look at the toxicity mechanism, there is this potential inflammation from the toxicity which then may create histamine, and that histamine can easily create issues with vasodilation by blocking uh nitric oxide, is that correct?

Evan Brand: Yup. So-

Dr. Justin Marchegiani: I wanna make sure I say it right, so I- I get it confused. There’s laughing gas which I think is nitrous oxi- nitrous oxide, and then nitric oxide is NO, NO, right?

Evan Brand: Yeah.

Dr. Justin Marchegiani: [Crosstalk]

Evan Brand: Yeah, nitrous. I believe the nitrous oxide, I believe that’s fully different, I’m just gonna type in nitrous oxide, versus nitric…

Dr. Justin Marchegiani: Yeah, one was- one was the laughing gas anesthetic, and then the other one, I think it’s NO.

Evan Brand: Yeah, NO and then I think it’s N- is it N2O, let’s see. Nitric oxide is NO, it’s not the same as nitrous oxide, N2O. Nitric oxide is one molecule of nitrogen, one molecule of nit- uh, oxygen. Nitrous, has 2 molecules of nitrogen and one of oxygen, that extra molecule changes the gas completely.

Dr. Justin Marchegiani: Yup, exactly. So, NO, we’re talking about, not the laughing gas, when you can go see your dentist, and you make a lot of this. And now, one other thing that decreases nitric oxide, NO, is gonna be fructose. Lot of fructose, lot of carbohydrate, this is the one of the major mechanisms behind high blood pressure and extra fructose, and extra sugar, primarily in the form of fructose, right? But that’s gonna decrease endothelial synthase or endothelial uhm, synthase which it helps open up. It’s the enzyme that help with nitric oxide stimulation. Nitric oxide opens up blood vessel. So imagine we’ve got this garden hoses on the side of our neck called our carotids, and these essential garden hoses, if constricted, decreases blood flow to the frontal cortex, which then decreases nutrition, decreases oxygenation, decreases the ability for us to calm down inflammation, and that can manifest itself in depression. And today’s podcast topic is gonna be anxiety. So, very easily there.

Evan Brand: Yeah, you could have anxiety just from drinking soda and eating pop tarts. I went over to my mother-in-law’s-

Dr. Justin Marchegiani: Yup.

Evan Brand: -and she still has pop tarts in her pantry. I’m like-

Dr. Justin Marchegiani: Oh my God.

Evan Brand: -“What the heck is a pop tart?”, so I look at- you know, I ate that as a kid, so I look at-

Dr. Justin Marchegiani: Yeah.

Evan Brand: -the ingredient list, and there’s like 3 different types of corn syrup in there, it’s like-

Dr. Justin Marchegiani: Oh my God.

Evan Brand: -corn syrup- it’s like corn syrup solids which is guess what, that’s fructose, you’ve got high fructose corn syrup, so-

Dr. Justin Marchegiani: -Right.

Evan Brand: -small fructose-

Dr. Justin Marchegiani: Right.

Evan Brand: -and then you got like uh another- another corn syrup added in there somewhere- somewhere. On- and then on top of that is, you’ve got enriched wheat and uh, there was some like BHT and bunch of other preservatives in, I mean, so people say, “Oh, well, I- I’m not drinking soda”, but if you’re eating pop tarts, that’s just as bad, you’re still getting high fructose corn syrup, I mean, high fructose corn syrups’ in every process thing ever. You go to the restaurant, you go get a grass fed burger, and you get sweet potato fries, well, then you do the standard ketchup on the table, that ketchup is high fructose corn syrup. So, then you’re in the same boat again.

Dr. Justin Marchegiani: I know. And then we don’t even talk it about. You know, the high fructose corn syrup primarily comes from corn, so it’s not organic, you’re getting glyphosate which is roundup residue. And then also there’s some that a lot of the processing of high fructose corn syrup conventionally, involves a mercury preservatives. Then there’s potential mercury exposure that you’re getting too. So you have mercury and around up, and then, uhm, then you have the inflammation by the de- by decreasing the uhm- the nnn- nitric oxide which vasodilates. So we have a couple of different mechanisms that are really throwing us downhill.

Evan Brand: Yeah, people are saying, “Okay, why are you on a tangent about ketchup and high fructose corn syrup? How does this relate to anxiety?”. Well, because it’s creating inflammation, and the inflammation makes your blood pressure go up. When your blood pressure goes up, you feel anxious. You can feel flush, you can feel-

Dr. Justin Marchegiani: Yes.

Evan Brand: -like your throat is closing, you can feel chest tightness, you can get tremors-

Dr. Justin Marchegiani: Yes.

Evan Brand: -or palpitations like, when your blood pressure is up, trust me, I’ve had different personal experience, it does not feel good to have high blood pressure. Even if-

Dr. Justin Marchegiani: Exactly.

Evan Brand: – it’s just temporary.

Dr. Justin Marchegiani: Exactly.

Evan Brand: Oh, you mentioned the- the life stress too, like the cortisol piece. So cortisol is a big issue with anxiety. You and I have tested thousands of people at this point, we’ve seen high cortisol and low cortisol, both can cause anxiety. So that’s why it’s important to test, not guest, because you may look at someone’s case history and it may sound like, “Oh, my God, this person…”-

Dr. Justin Marchegiani: Yeah.

Evan Brand: -“…gotta have high cortisol”. But then you test it, and they’re just flatlined.

Dr. Justin Marchegiani: Exactly. Yeah, exactly. So, uhm, very-very important. So, if you look at the diet and lifestyle stressors, that’s a big component. Of course, emotional stress is gonna be a big one. What’s happening with emotional stress? Typically, we’re having surges of cortisol and adrenaline. Right? And of course, What’s adrenaline gonna do? Adrenaline does cause vasoconstriction, it tends to shut blood flow to the arms and legs to run, fight and flee. So it’s primarily going here for prehistoric survival mechanism, and it tends to be going away from the brain, because you need parasympathetic function to have good blood flow to the in- to the internal organs in the brain. So you’re gonna have less to the brain, and that’s part of the reason why when you’re stressed, and you have over sympathetic, over cortisol, over adrenaline, you tend to have a less blood flow to the brain, and that’s why people make uhm a lot of poor decisions when they’re stressed. There was- I was reading a study at one point when they talked about uh a lot of violent criminals in jail, that a lot of violent criminal episodes have been made where in a hypoglycemic state by the criminal. So-

Evan Brand: Wow.

Dr. Justin Marchegiani: -essentially with that, your frontal cortex has about, I think it’s like, 25 or 20 milliseconds to shut down and impulse. So like, you see someone like that walks by that like, really, bugs you, you’re- you kinda think, I wanna get them, well then your frontal cortex goes nope, not- not a good idea. So when you have that decreased frontal cortex activation, which could be decrease from cortisol and blood sugar and stress, then you’re gonna have that inability to not- to not uhm dampen down that impulse.

Evan Brand: Well think about, I mean, I just saw a video couple weeks ago of a prisoner who was like sitting in like a courtroom, and he goes up and he just like smacks the lady in the head. One of the ladies is like standing, like testifying, he goes up and smacks her in the head and then he immediately just sits down like he realizes, “Oh, my God, what did I just do?”.

Dr. Justin Marchegiani: I know.

Evan Brand: The prisoner diet, I mean, their diet is terrible.

Dr. Justin Marchegiani: Oh yeah, I mean, if we were really were interested in this society, uhm, rehabilitating prisoners uh, you’d start with nutrition. I mean, I would’ve go in there number 1, and involve cri- uh, I’d have criminals working on a farm, producing all their own foods, so society didn’t have to pay for it, number 1. And then number 2, get the nutrition up. It’s impossible to rehabilitate someone with very poor uh, brain function from amino acids or good healthy fats. They done studies before, I’ve- it was uh, in the food connection book, and they talked about adding omega 3’s in the prison. And then helping to decrease the violence rate in the cri- in the prisons like significantly. So-

Evan Brand: I’ve read that.

Dr. Justin Marchegiani: -fatty acids are very important for anxiety and mood and behavior function because number 1, your brain’s primarily fat. It’s 70% saturated fat and cholesterol. But omega 3 fatty acids are very anti-inflammatory. So if we have inflammation and going on in the brain, we have surges of cortisol, right, we have blood sugar fluctuations, we have our microglial cells in the brain are activated, these are our immune cells in the brain, they’re gonna be activated when inflammation is going on, whether it’s from foods or stress, and good omega 3 fatty acids, anti-inflammatory fats like omega 3s from DHEA and EPA, these are 20 and 22 carbon chain of fat- fatty acids are very anti-inflammatory.

Evan Brand: A lot of people are against fish or they just simply don’t do enough high-quality fish. So like in- we use triglyceride form fish oil-

Dr. Justin Marchegiani: Yup.

Evan Brand: -we work with professional health care companies. So-

Dr. Justin Marchegiani: Yup.

Evan Brand: -that’s a product that you may wanna have in your tool box if you don’t already. Don’t just go to ___[13:22] and buy their fish oil and assume that’s gonna be good enough, it’s not, they’re using ethyl ester form which is where they attach an alcohol molecule to the fish oil, your liver has to process that. If your products smells fishy, if you have fish burps, throw it away, rancid by with Justin’s product or by my product.

Dr. Justin Marchegiani: Yep.

Evan Brand: Because we wanna get you on a high-quality fish oil for your brain.

Dr. Justin Marchegiani: Exactly. And if you’re consuming fish 3 to 4 servings of fish a week is great, even if you’re pregnant, just really- just focus on high selenium to mercury ratio fish. So your wild Alaskan sockeye, your Cod, your haddock, your skipjack tuna, these are gonna have a higher amount of selenium to mercury, and that will help essentially uhm bind up any mercury that maybe there. And if you’re on a fence and you’re doing sushi, you can always do things like some activated charcoal, things like that, just to be on the safe side.

Evan Brand: Oh, by the way, I bought a TV for the first time in ten years.

Dr. Justin Marchegiani: Oh, wow!

Evan Brand: And uh, it was because I wanted to watch the new documentary called “Our Planet”-

Dr. Justin Marchegiani: Oh yeah.

Evan Brand: -tune in Netflix with David Attenborough, and uh, I was looking at some, I mean, our ocean is basically screwed, but uh hopefully we can turn it around. But he was s- showing some of the Bluefin tuna which are like a- almost all the fisheries are being overfished and the whole ocean’s collapsing because we’re overfishing. They were talking about some of this tuna that could be 1000 pounds. It’s like no wonder they’re so toxic with mercury, they’re a thousand pounds.

Dr. Justin Marchegiani: Yeah, yeah, I agree. I hundred percent agree. But uhm, yeah, it’s really important stuff. I’m glad you found the other TV man, I mean, I don’t watch TV outside a couple of Netflix show, I mean, right now, I mean, I watch Game of Thrones last night, that was, man, that is my show right now. Love it.

Evan Brand: I- I’ve never checked it out. But I’ll have to, but people should watch that “Our Planet” because it is- you should watch it too, it’s amazing-

Dr. Justin Marchegiani: Yeah.

Evan Brand: -it really- it- it really says, “Hey look, like, we’ve got a lot of issues, there’s still some beautiful stuff left on planet Earth, but, we’ve really gotta turn things around and, I- I think with our podcast, we’re helping to turn things around from an ecological perspective because we’re encouraging people to get local meats and pastured meats, and we’re trying to turn away from the conventionally factory farmed animals which are creating a lot of damage to the water table and to the soil, and, you know, buying local beef. Because if you go to the grocery store now, you’re gonna see grass fed from Brazil, and they’re cutting down the rainforest in the Amazon to grow uh, soybean and also they raise cattle for grass fed beef. And so, you wanna make sure you’re not buying Brazilian grass fed beef, and you can get it locally, it’s so easy. And then also, with your palm oils. So like if you do snacks like plantains like I do, I love plantain chips or plantain strips. Make sure your palm oil is a certified palm oil, so it’s sustainable and you’re not cutting down the Orangutan, their forest in Indonesia, they’re critically endangered now because of us. Cutting down there, uh, you’ll see it too in the- in the documentary where they just clear cut native rainforest and they’ve replaced it with just a mono culture of palm, uh, palm trees that- that for the palm oil. And so, you know, even look at Doritos like you look at the- a back of a bag of Doritos, even Doritos are contributing to deforestation because the palm oil, it’s in there. It’s not sustainably certified.

Dr. Justin Marchegiani: Right. So, I mean, what’s the solution is? Okay, ’cause, we need palms, so, or you cut it down just- just plant it as you cut it essentially?

Evan Brand: Well, the- the goal is just to have sustainable farm. And so, I don’t know exactly what the- I think it’s called RSPO, there’s a whole organization that goes in and certifies them, I don’t know if that means they’re helping to protect other land like if they buy a thousand acres, they only, you know, grow palm oil on half of it, I- I’m not sure of like what they’re doing, but I do know that when you see an RSPO certification, it’s gonna say, “Hey, this is a certified sustainable…”-

Dr. Justin Marchegiani: Yeah.

Evan Brand: “…source” of palm oil.

Dr. Justin Marchegiani: Yeah, I’ve seen a lot of articles on these types of topics, they talk about, like the- the- the number 1 way you can fix a lot of these things, is you don’t rent these lands to corporations, you have the corporations buy it. Even the corporation buys the land they have a more- s- a stake in the land to keep it solvent so it can produce more product in the future, right? Whatever that there is, right? So, if you- if I buy a land to cut trees, I’m more likely to then replant all the trees so I have more trees to cut in the future. But if I’m just renting it, think about how you treat your car if you’re renting it versus it’s your car.

Evan Brand: Oh yeah.

Dr. Justin Marchegiani: I’ve seen some articles on that type of uh, topic from a root cause perspective ’cause you treat things differently when you own it, when you have a stake in it.

Evan Brand: Absolutely. You hit a big pothole in the road, alright, “Oop, it’s a rental, so what?”.

Dr. Justin Marchegiani: It’s a rental- right, it’s the same thing when it- when you just have- I- I have logging rights for 10 years in this area. I’m just gonna wipe it clean, it’s not my property, I don’t have to worry about it, right?

Evan Brand: Yup.

Dr. Justin Marchegiani: It’s kind of a mindset. So, uh I think we start first by decreasing the pesticides in the environment, and the glyphosate, number 1, and then number 2, the mono-culture stops. And if you don’t have the conventional GMO crap and the high fructose corn syrup, that’s where all the corn, and the grain, and the GMOs are primarily coming from. So if you just go organic, you’re gonna totally support more local sustainable farming and it’s gonna be in this monoculture formats, putting tons of pesticides, tons of glyphosate, and that’s affecting runoff in our water too. And how does this connect back, well, it’s gonna connect back ’cause it’s a stressor, it’s- it’s inflammatory to the brain. And a lot of times the glyphosate and a lot of these pesticides can affect the brain as to the gut. Because what they can do is, if you look at Stephanie ___[18:40] at MIT it’s gonna decrease that brush border where you produce enzymes. It’s gonna make the gut more permeable and more leaky, and that leaky gut is gonna allow more stuff in your gut to get into your bloodstream like endotoxin which is lipopolysaccharide from bad bacteria, it’s gonna allow undigested food particles to get into that bloodstream, that’s gonna activate the immune system, that’s gonna create more gle- microglial activation in the brain which is gonna create cognitive issues, brain fog, mood related issues. So, anytime we look at the brain, whether it’s anxiety, which what we’re focusing on today. Any inflammation in the gut can then drive inflammation in the brain. Inflammation in the brain manifests in these mood-related issues.

Evan Brand: Yup. When I had- oh, and by the way, Vietnam banned glyphosate. So, good job Vietnam. Uh, I had major anxiety when I had gut infections, and so, my anxiety is much better, but then it was caused from another- another mechanism, right? So, fixing the gut was critical for me to fix my anxiety. Now we could- we probably should do a part 2 on this, ’cause, I mean, we could spend an hour just on omegas and probiotics and restoring gut health but-

Dr. Justin Marchegiani: Right.

Evan Brand: -we haven’t even got into talking about like, uhm, relora, and ashwagandha, and holy basil, and, uh, sensory deprivation tanks, and massage, and acupressure, and acupuncture, and essential oils, and, uh, gaba and- and pharma GABA and theanine and, and uh, lemon balm, and I mean there’s so much to cover with this anxiety conversation but, I’m glad that we disco- we- we discuss all of these major critical pieces first like restoring their- your brain health, making sure you’ve got good omegas, testing and fixing any cortisol issues, avoiding glyphosate so you’re not killing off your good bacteria and promoting bacterial overgrowth because if we just skip straight ahead to the magic pill like your theanine and your GABA, well then people aren’t gonna listen to the first part.

Dr. Justin Marchegiani: Right. We wanna make sure the- the biochemistry and the underlying physiology makes sense. If you- if you- that makes sense, we can plug and play various supplements, various diet or lifestyle strategies to helping to affect the root cause.

Evan Brand: Yeah. So we’ll do a part 2. Let’s do a part 2 on anxiety later because I think that we can do a whole hour just on how you use specific remedies, like I’ve got a whole timing to adaptogens, like I may do, you know, ashwagandha more towards the evening to help kinda calm down and settle at night versus I may go holy basil  in the morning to stimulate. So there could be a full circadian rhythm to your supplementation as well.

Dr. Justin Marchegiani: Exactly. And of course, movement has a huge effect. Apparently, I think, mo- movement is gonna help because you’re producing various beta endorphin which has anti-depressant qualities to it. And beta endorphin is- is a 19 uhm amino acid compound. So there’s 19 amino acids that make up beta endorphin. So you need protein to make it, okay, uh number 1. So movement is gonna help with that. I think movement also helps with insulin resistance and insulin sensitivity. So it make yourselves more insulin-sensitive and helps kinda soak up extra blood sugar. So if you have these glycemia issues, it’s gonna help soak up that extra blood sugar that’s hangin’ around. And essen- essentially give you a bigger sponge, A.K.A. bigger muscles, especially if you’re doing more resistance training and integral training, it’s gonna give you bigger muscles to soak up extra blood sugar, as well which is helpful.

Evan Brand: That’s very cool.

Dr. Justin Marchegiani: Yeah.

Evan Brand: I’ve noticed, my blood sugar has been on the lower end like I was- I actually- my wife let me uh prick her finger to check her blood sugar which is good. We did like a grass fed steak, we did some steamed broccoli with butter, and then we did a big sweet potato. So we have the same exact meal, we ate it at the same exact time, and my blood sugar, within 45 minutes, we’ll call it 1 hour, after that-

Dr. Justin Marchegiani: Mm-hmm.

Evan Brand: -my blood sugar was already backed down to an 80 and hers was [crosstalk]- and hers was a hundred. So I thought, hon, now of course she’s pregnant, so maybe that has an effect [crosstalk], I thought, [crosstalk] blood sugar crashing too quick, how am I already back down to an 80 one hour later and all I had was, you know, I had a sweet potato. I thought for sure, it’d be above a hundred still.

Dr. Justin Marchegiani: Yeah, and just could be that you’re really insulin-sensitive. And sometimes if you- if you do too much carbohydrate for you, a lot of low blood sugar issues is from too much insulin. So if you stimulate too much insulin from too much carbs, that can drop a but 80 I don’t think it’s that bad it. I would wanna see how 2 hours looked-

Evan Brand: Yeah.

Dr. Justin Marchegiani: -and 3 hours looked and to see if you kinda leveled out, and then how you felt too.

Evan Brand: Yeah, I- I feel kinda low at- at 80. Do you- do you track it all? What number you- you feel bad at ’cause I mean, on the conversation of anxiety, like if I get a bout of anxiety and I feel kinda shaky or irritable or nervous, uh, I’ll check my blood sugar and sometimes I’ll be at- maybe a 70, maybe mid-70s, I’ll start to feel weird at that level.

Dr. Justin Marchegiani: Yeah, it’s hard, right? Because what happens is, your faster your blood sugar goes down, the faster adrenaline and cortisol is there to pick it up. So if your blood sugar is like this, and it’s a slow arc-

Evan Brand: Yeah.

Dr. Justin Marchegiani: -and we’d take a picture of it right here. That’s different than taking a picture of it right there when you eat too much carbs and it’s coming down like this. So the steeper the angle is, the worse for anxiety and mood. Because the steeper the angle, that means you’re crashing at a faster rate, which means there’s more likely that you’re gonna have adrenaline and cortisol lift you up. So the more it’s like this, then it’s kinda tangentially coming down, less chance of cortisol and adrenaline to pick it back up. But if it’s coming like this and you grab a snapshot there, then there’s more likely to be adrenaline and cortisol and you may feel that. So when people say, you know, hypoglycemia issues, you look in the Merck Manual. What does Merck say, oh well, you know, take some sugar pills all this crap, that doesn’t fix the root cause of how the hell you got there.

Evan Brand: That’s right.

Dr. Justin Marchegiani: ‘Cause how you got there, we’re doing that exact same strategy, so what happens is, people that follow those kinds of conventional medical advice for nutrition, they’re on this perpetual blood sugar rollercoaster all the time almost.

Evan Brand: Yeah, the people that like travel with the glucose tablet you’re talking about, yeah, I’ll just eat some candy, let me eat some skittles, okay, my blood sugar is fine now, I had skittles.

Dr. Justin Marchegiani: Exactly. Does not fix any of the issues.

Evan Brand: And see, I don’t do that. I don’t- I don’t do any processed sugars per se, you know, I had like some blueberries with breakfast, uh, so, I’m just wondering-

Dr. Justin Marchegiani: [Crosstalk] what the heck is happening there? You already- you over- you overshoot your blood sugar from too much carbohydrates and refined sugar, so you have a really steep drop in your blood sugar, then it comes down, and then you’re like, “Oh, I’m gonna follow the conventional medicine advice”, and so you come back up again, and then you keep on doing these high and low peaks, and you keep on having the smooth it up with extra carbs and sugar, versus kinda come in there like this, where you’re sneaking along, versus falling off the cliff. Does that make sense?

Evan Brand: Oh, absolutely. It’s a much- it’s- it- it’s- people don’t understand, I mean, when we look at like you said, like violent crime in prisons, or we look at car wrecks, or we look at people shooting each other, or we look at any big situation happening where someone’s doing something stupid, I’d put a high amount of money on the fact that it’s probably someone who’s on a conventional American diet, with a crazy blood sugar pattern, and they’re hypoglycemic, you can’t think straight, trust me. My blood sugar is low, I had period where I was like a 58 or a 60, I couldn’t think straight. I mean-

Dr. Justin Marchegiani: Right.

Evan Brand: -you literally can’t think straight and make decisions. All you can think about is, “I gotta do something, I gotta eat something”.

Dr. Justin Marchegiani: Exactly. And, I’m doing some kinda hand gestations here to kinda symbolize what’s happening with the blood sugars. If anyone’s listening to this on the podcast, feel free and check below. You can access the video here too, so we’re- we’re live on YouTube as well as Facebook to see that.

Evan Brand: Well let’s- let’s wrap it up, but I do wanna go one- one for the question for you, and how would you recommend approaching that? So if you’re someone who, like me, you’re away from refined carbohydrates, except I will do some organic white rice, I will do some sweet potato, those are my starches of choice. Uh, so, in that situation, is it just more adrenal support for me, is it just staying low carb for my breakfast and lunch, and only doing the carbs at dinner like how would you say if I’m looking at glucose and I’m seeing that I’m going back down to like a mid-70’s or an 80, and I wanna hang out around maybe 90, ’cause I feel better there, how would you- how would you achieve that, is it possible to do that with just like fat and proteins?

Dr. Justin Marchegiani: Well, number 1, I think with- you’re a leaner dude, so I will first look at like what your activity levels are for the day. If you’re not super active physically, then I’d be focusing on more proteins and fats for- for your fuel source, and then, you know, work on timing more your carbs later in the day. There’s some data that carb backloading, doing carbs later in the day tends to be a little bit better. Again, there are other people- this is so controversial, but I mean, there’s been research on it, people in the backloading carb community kinda know that people tend to do better with carbs at night time, there’s some data where people take their carbohydrates and they put all at the back end of the day, and then while the control group does it throughout the day gradually, and there’s been better weight loss, patterns doing it, like that at night, so there is that benefit. So, I would do more of the carbs at night, and then I would keep more protein and fat as- as kinda your foundational base. Think of protein and fat as like logs in the fire, so if you have a good fire, the logs from the fire gonna keep that fire burning sustainably. The carbohydrates are gonna be like kindling your twigs, and the more refined the carbohydrate, or the more high- higher glycemic index it is, the more it’s like, it- it’s like gasoline or paper, right, it goes up faster. But if you have logs in that fire, that’s gonna keep that fire burning long and strong versus if you just do paper twigs and gasoline, you’re up and out. So, twigs and paper and gasoline is the, uhm, too much refined sugar, not enough protein, fat, and then you have this up and down swings of blood sugar. The logs in the fire are gonna be like the high-quality protein in fat, and then we have to dial in the carbohydrates according to your metabolic needs.

Evan Brand: I need to check it act, I mean, I like data, you and I both do. So, I need to just check- check and see… You- can my body take? Let’s say I do like a grass fed beef steak, right, and it’s like, let’s just make something up, you know, 15 grams of fat and 15 grams of protein.

Dr. Justin Marchegiani: Right.

Evan Brand: In theory, I should be able to take that beef steak and convert that over to glucose, even though it’s primarily fat and protein, correct?

Dr. Justin Marchegiani: Yeah, I mean, you will be able to do with some of that for sure. I mean, your brain know it needs about 20 grams of glucose today. So you won’t get a- a ton-

Evan Brand: Okay.

Dr. Justin Marchegiani: -of glucose out of it, but yeah, you’ll get a little bit of glucose, via gluconeogenesis, and then you’re also gonna get more ketones, right? And people that have- they’re higher in ketosis, their blood sugar may go lower, but you gotta remember, their blood sugar can go little bit lower because they have more- other fuel substrates in the bloodstream called ketones. So, they may be able to go lower. Where some is jackin’ the blood sugar up and down, through a reactive hypoglycemia e- episode, right? Reactive is up, and then you’re reacting by going down fast. It’s a steeper angle of that blood sugar dropping. You’re gonna have less ketones there because you haven’t done the right things in your diet over a period of a couple days or weeks to get in the ketosis, where you have more ketones. Uhm, a- anytime you’re surging insulin, you’re gonna be not- you’re gonna be kicked out of ketosis, because you need lower insulin levels to be making ketones. High insulin blocks ketosis. So for keeping our blood sugar under control, and we’re kinda snaking along and not jacking our blood sugar up too high above a hundred or 110, 120, then we’ll have more ketones, and therefore your blood sugar could drop a little bit lower. But I even see some of this people that are really doing a lot of ketogenic diets then they even go a little bit too long, and I’ve seen people posting 50 and 60 for blood sugar range, that may be a little bit too low. But I mean, tested out, try and see you feel, see how you look, see how you perform and see if we can uhm, connect the dots there.

Evan Brand: That’s cool. So, maybe I find it at 70, if I have some ketones running in the background.

Dr. Justin Marchegiani: Yes. It gives more- it gives enough ketones in the background. I think that’s the key thing.

Evan Brand: Makes sense. Well, let’s do a part 2 on this later but we gotta wrap it up [crosstalk]-

Dr. Justin Marchegiani: [Crosstalk] it just depends, if your body needs more glucose because of what you’re doing, uh stress wise, then, you may have a cortisol surge to fill in the gap via gluconeogenesis. So-

Evan Brand: ‘Cause that’s the thing. So, if I’m at a 70, I feel like I’m getting low, you can feel that anxiety starting to creep in at a 70, it’s like well, do I go and eat something like an apple, which I know is gonna raise glucose, or do I go do a beef steak, or do I do a beef steak in an apple to get glucose up?

Dr. Justin Marchegiani: Yeah, O would probably do beefsteak in an apple.

Evan Brand: Do both.

Dr. Justin Marchegiani: Yeah, I will probably do both.

Evan Brand: So you can stabilize it with the fat and the protein, but then you do have some actual glucose coming in at the same time.

Dr. Justin Marchegiani: Exactly. And to get- there’ll be fructose in there, but fructose is 55, 45 or 50, it’s close. So you- even though you get fructose in, you’re gonna get-

Evan Brand: But you don’t wanna do just the apple ’cause if you do just the apple, then you’re up and down again, depending on what type of the apple too. So that’s why we always talk about like putting almond butter, something else on there, coconut [crosstalk]-

Dr. Justin Marchegiani: Or you even do a Granny Smith which has- has- half the amount of sugar as well. But then you get some of the fiber too. So it’s less- you- you’re not gonna quite have that as much with lower glycemic fruit with full fiber, but yeah, you still- it’s good idea to always have the protein and fat along with it, for sure.

Evan Brand: I stay away from Pink Lady. I tested a Pink Lady apple; I went from like a 75 to like a hundred and thirty with the Pink Lady Apple. I mean, that thing is like just candy.

Dr. Justin Marchegiani: Oh yeah. [Crosstalk]. Yeah, exactly, that’s why- my- I primarily do Granny Smith, half the sugar and uhm, I’ll typically do it with some cinnamon on it and some almond butter.

Evan Brand: That’s delicious. Woooh!

Dr. Justin Marchegiani: Love it. Well, hey, Evan, let’s wrap things up, we’ll be back next week and we’ll talk a little bit more, we maybe can expand upon this topic or even choose a- a new topic. So appreciate all you guys in the background with great questions. We’ll continue to expand on this conversation here in the weeks to come. Anything else Evan you wanna leave to listeners with?

Evan Brand: Yeah, people just reach out. If you need help, work on your blood sugar, stabilize it, but, you know, this stuff can get tricky. So if you need help, don’t hesitate to reach out, we can work with you around the world. Justin’s website is justinhealth.com, my site is evanbrand.com. We look forward to helping y’all.

Dr. Justin Marchegiani: Thanks so much guys, you’d have a phenomenal day, we’ll talk soon. Take care Evan! Bye.

Evan Brand: Bye.


References:

https://www.evanbrand.com/

https://justinhealth.com/

Peri-Menopause and Female Hormone Balance Solutions | Podcast #213

Peri-menopause can be hard on some women. It brings fatigue, mood swings and sleep troubles, a stressful transition that can last for months or years before menopause.

In today’s podcast, Dr. Justin Marchegiani explains the process of peri-menopausal stage and its effect to the body. Learn how the lowering levels of progesterone make one’s system more estrogen-dominant, the different issues brought by peri-menopause especially stress, mood issues, hot flashes, depression. Also, learn how to minimize its effect. Continue for more and don’t forget to share. Sharing is caring!

Dr. Justin Marchegiani

In this episode, we cover:

02:26    Adrenal Gland

04:31    Female Hormone Cycle

07:31    Hormone Physiology 101

26:27    Stress Response Buffering

12:35    Effects of Estrogen Exposure to Men

Youtube-icon

Dr. Justin Marchegiani: Hey guys! It’s Dr. Justin Marchegiani, welcome to today’s podcast. Uh, congratulations to Tom Brady and the New England Patriots, great go- not really a great game on the offensive side, great defensive game. Uh, 6 superbowl victory for Tom. And I did a podcast on Tom’s performance secrets 2 weeks ago which become even more pertinent today based off of his victory. He is officially the go- greatest of all time. So, really good uhm- to go back and revisit that podcast, lots of good insights in regards to sleep, in regard to hydration, in regards to nutrition, reducing inflammation, uh various training techniques, all these things I think are, a conglomerate of tools that uh- Tom uses to improve his performance, heal fast and keep his uh, pliability and performance up the uh- at the, you know, at the highest age possible. Really, to be a successful quarterback in the NFL, it’s pretty amazing.

So, today, we’re gonna open it up here for uhm… here, I kinda like- maybe a little live podcast here. Anyone wants to chime-in in these specific topics they want me to go into today, we can just choose a topic and just go off the cup and go live. I’m on Facebook as well so, feel free and check in with me on any of these mediums here so far. I’m gonna dive in one topic here today. We’ll go in on peri-menopause. So peri-menopause is really interesting. This is the kind of the phenomenon where you’re in this transition time of going into full menopause or- typically peri-menopause is just starting to miss some periods, you’re maybe in your mid- ty- typically upper 40s. Usually menopause starts between 48 to 51 and it can take 10 years, meaning the symptoms that you deal with during menopause, that can take up to 10 years sometimes. The hot flashes, the mood issues, the depression, uh anxiety, uhm those type of sleep issues, scrappy skin, all those things can kind of con- you know, consolidate and happen over a long period of time. Typically, peri-menopause is that- one year. Once you get in the menopause- menopause typically is like, once you’re been no cycle for 12 months. So, peri-menopause is this in-between time  where skipping cycles, maybe you have a period every 4 months, or 6 months, or you’re kinda lost your cycle regularity, you know, fertility may not quite be there, you may not be ovulating as much- uhm- you start to see your cycles just getting more and more irregular, typically in you’d mid- typically upper 40s when that starts to happen.

Now, what do we do about that? So, first thing is, make sure you’re not getting exposed to toxic hormones in your foods or in the environment. That’s number 1. Uh, number 2, the biggest hijacker of your hormones is gonna be your stress hormones, A.K.A. cortisol and adrenaline. So it’s really important that you get your adrenals looked at if you’re worried about peri-menopause because, DHEA Sulfate, this is the major sex hormone precursor that’s made by your adrenal glands. This is actually coming from your adrenals and it’s a precursor to make more estriol in women. It can go more testosterone in men. But estriol is that predominant estrogen that you’re gonna have when you start becoming more menopausal. Typically when you’re cycling and fertile, it’s more estradiol, E-2, the “di” is kinda- right, 2. And then estriol, or the TRI, that prefix for 3. So you start to make more estriol, and that’s gonna be more anticancer. It’s gonna be- it’s have some really good anti-aging benefits. Estriol’s really important for hydration, that’s why low estriol- low estriol can- can create vaginal dryness. It’s also a really good anti-inflammatory, it really helps with brain inflammation. This is why a lot of mood issues and brain fog and cognitive issues start as you become more and more uhm- peri-menopausal into menopause.

So we have to look at the adrenal glands, that’s number 1. Because these adrenals make DHEA, also cortisol hijacks your hormones. Cortisol increases blood sugar, and also decreases protein synthesis, meaning, you have less protein going to build up your brain chemicals and build up your muscle tissue, and that protein is primarily running through gluconeogenesis where it’s shredding up that protein and making more glucose out of it. That’s what stressed us. People get more flabby, they get more cellulite because of cortisol. Breaks down connected tissue, and it breaks down amino acids. So, your- getting your adrenals looked at is really important.

Uh, number 2 is looking at your female hormones as many women as they go more into peri-menopause, they become more estrogen-dominant. And the reason why is, because we talked cortisol hijacking, your hormones- it does so, ’cause it pulls progesterone downstream to make your stress hormone. So this is important. The more stressed you get, the more you deplete progesterone, that puts you more into an estrogen-dominant state. Typically, we have more progesterone than estrogen. It’s about a 20 to 25 to 1 ratio progesterone to estrogen, and when you start going estrogen-dominant, people think, “Oh, that means estrogen goes higher”. No, it just means there’s ratio, it starts to drop. So you still may have more progesterone, there’s that ratio drops down a little bit, and you start to see estrogen creep up, but you may not see estrogen ever go above progesterone. Just keep that in the back of your mind. That’s gets commonly confused.

So we have the progesterone there. And typically, when cortisol’s prolonged, this also affects the HPA, H-P-A-T, H-P-A-T-G-G: hypothalamus, pituitary, thyroid, adrenal, gonadal, gut access. So it affects that feedback loop from the brain, and the hypothalamus and the pituitary ups- upstairs to that feedback loop of the glands secreting hormones downstairs. And this is important, so we start to see cortisol rhythm operations. The cortisol rhythm starts fluctuating. We start to see it in women with their cycle operations. A lot of times we just see a lot of PMS or the extreme PMS is PMDD, which is that week or so, before you actually menstruate or bleed. And then we also see a lot of- a lot of times, sometimes shorter cycles, going from 28 to 26 to 24 to 22. So we start to have a shorter luteal phase, just really important ’cause your luteal phase is that primary phase where you’re making more progesterone. So we do test while we actually look at progesterone every other day for a full cycle. And one of the things we’ll start to see is, your overall progesterone that you make throughout the whole month, typically should be above that 3000 marker so, it starts to drop. You start to see it drop. And that’s big, ’cause that’s kind of like looking at your overall progesterone sum, we start to see it drop, and a lot of times that can happen when you compress that luteal phase when you shorten it, ’cause you just have less days where you’re even making progesterone. Uhm, that’s a big one. So we start to see cycle aberrations there, we could see a shorter luteal phase, we could see a longer follicular phase, we may be out of sync, or we’re not ovulating at that right time and your ovulation could be totally off, or maybe you’re not even ovulating. ‘Cause, you know, to have that good ovulation to signal, we need a- [clears throat] a rise in estrogen followed by rise in progesterone and then estrogen kinda pitters out while progesterone stays high and drops. This is kind of our typical rhythm, and how women’s cycle work. So, just kinda first thing that happens, those gotta- kind of hormone physiology 101.

So, we start off by menstruating. That menstruation is typically signaled by a drop in progesterone and estrogen. First thing, progesterone and estrogen drop. That’s step 1. 2, menstruation happens after that, that’s the shedding of the uterine lining. We want brighter blood that’s more oxygenated, more fresh, for starting to see browner, thicker kind of clottier stuff, it just could be- uhm- the uterine lining from previous cycles that didn’t flush out. So, 1, drop in progesterone and estrogen, 2, menstruation, that’s gonna happen for a few days, anywhere between 3 to 7 days, okay? We don’t wanna go more than 3 to 4 tampons per day on average. For our average high, is if not we lose too much blood, we go hemorrhagic, we go anemic because of that. Step 2 is FSH starts to increase. FSH is our brain hormone, follicle stimulating hormone. That FSH start to make the follicle grow a little bit. That follicle starts to produce estrogen. Estrogen starts to rise, right? As estrogen starts to rise, that starts to signal luteinizing hormone, which is our other brain hormone that talks to our ovaries. And then progesterone starts to rise typically around day 12 to 13 after that. So here we are at day 12 or 13, estrogen’s kinda topped out, that signals LH, then we have progesterone going up like this. So progesterone’s going up, and then at some point, estrogen starts to fall again, progesterone stays up, and then around day 28, they crash together and that signals the whole entire step again.

So, drop in estrogen progesterone, signals bleeding, FSH, increases, FSH creates more estrogen, more estrogen creates more LH, more LH creates progesterone, estrogen starts to drop, progesterone stays high, estrogen and progesterone drop and then signal bleeding at the end. So that’s kind of a general uhm, cycle physiology 101, Most people are clueless about that. When I talk to a woman, I say, “Hey how long is your cycle?”, the biggest kind of common misconception, “Oh, it’s 3 days or it’s 7 days”, like no, not your menstruation, your full cycle. Your cycle is from day 1, first day of bleeding to next day 1, typically 28 days later. Uhm- most people get that confused your cycles, your full hormonal rhythm, day 1 to day 1, how much you menstruate is gonna be your- your bleeding, your period time so to speak. Hope that helps. That’s a common misconception.

Alright, so we talked about adrenals, we talked about our female hormone cycle, we talked about hormones in the environment toxins. These things are really important because they disrupt, they put more stress on our metabolism to be our- to be our detoxification system to be able to metabolize hormones. Gut functions’ so important because this is where we absorb a lot of the nutrients from our food to make our hormones, right? Hormones are made from good cholesterol, right, it goes cholesterol pregnant alone and then 27 different hormones that spit out on the stress side, on the mineralocorticoid side and on- then on the anabolic estrogen progesterone, testosterone side. So we- we need to be able to absorb these nutrients so we can make our hormones. We need to be able to absorb nutrients to help buffer the stress response. Magnesium, L-Theanine, GABA, they help us buffer that stress response so we could- think of it as like, imagine buying a car where you can only shift it from first gear to second to third or fourth, fourth to fifth. So, all you can do is bring that car up from low to high but you can’t downshift. And a lot of people are in this place where they cannot downshift their metabolic car, so they constantly feel stressed, they cannot ever bring it down from fifth gear back to first gear. And this is one of the biggest issue- biggest issues we see, and if we can’t absorb our good amino acids, and- and- and make our good inhibitory nerves, transmitters like GABA, through L-Theanine, through magnesium, through dopamine through serotonin, we’re gonna have problems. And typically, this starts to mess up sleep. Starts to mess up our melatonin cortisol rhythm which is the next step. And that’s gonna be basically- melatonin goes up at night, cortisol goes down at night. We have this inverse relationship – melatonin up, cortisol down, right? We get this big “X”. And when cortisol stays high at night time, it disrupts sleep, it prevents melatonin from coming up. Melatonin is a powerful antioxidant, it’s powerful anti-cancer, it’s very anabolic, it helps you heal, recover, turn-over your neurotransmitter successfully and heal your body, ’cause you really tap into ’em, make a lot of your growth hormone in that first half of the night, 10:00PM to 2:00AM. So we wanna be asleep so we can plug in and access that growth hormone.

Okay, so we got our rhythm, cortisol, adrenals, digestion, absorption, and then also, the amino acids that we absorb through our digestive system, also help run our detoxification system. So, we wanna stop the toxins on one side, not drink out of plastics, not consume pesticides, consume organic, right, get, you know, higher quality step-4, step-5, if we’re using the whole food, step-method works, more grass-fed, pasture-fed, organic, the whole nine yards that’s gonna help us make more of the nutrients, absorb more of the nutrients where we can actually detoxify as well.

And then we talked about those hormones helping with sleep, helping to buffer stress. Uh, very-very important components to female hormone health, as well as make hormone health. Uhm- males really get the sure end of the stick, because there’s a lot of estrogens in the environment, you don’t have a lot of synthetic androgens in the environment, so men really get clavier because when men get a whole bunch of estrogen exposure, it starts to inhibit LH. LH is that upstream hormone in the brain that talks to the gonads, right? With the uh- the cells lay dig in the testicles to make more estrogen… I’m sorry, to make more testosterone so that estrogen disrupts that signal. Now we don’t talk to our testicles to make more testosterones, it starts to inhibit that. And it’s a- it’s a really a vicious cycle. With women, they just become more estrogen dominant, which is a good, that starts to mug their cycle. With men, it starts to decrease testosterone. And you start to see things like gynecomastia – man boobs. Uhm, maybe guys even being overly emotional because they’re- it starts throwing off testosterone-estrogen balance as well. So that’s gonna affect their mood and- and focus on- on the male side as well. And of course for the woman, it- it causes same things, ’cause they can create more PMS which can create irritability, breast ___[13:48], back pain, moodiness, irritability, sleep issue, all those things that you know, women do not like. And men don’t like them either, of course. It’s a two-way cycle in that for sure.

So we think we hit all the major things. I’m gonna open it up to questions, primarily on the peri-menopause, female hormone side of the fence. And again, this is total live podcast here. Uhm- again, I just- I interject a lot of clinical information ’cause I work with patients in the trenches. So if you have any of these issues and you wanna dive in, click below to make sure you subscribe, hit the bell, and schedule a consult with me and my staff. Let’s see what kind of questions we have here off the bat. Try to keep it pertinent on the topic if you can.

Alright, let’s see here. Uh, “How bad- how can a bad gut affect hormone?”. So it’s going to affect the two-wa- oh, couple of ways. We absorb all of our nutrients to create our hormones to our gut. Number 2, we absorb the nutrients to our gut to help us detoxify – number 2. And then number 3, dysbiotic bacteria increases an enzyme called beta-glucuronidase. And beta-glucuronidase, uhm deconjugates estrogen. So we have an estrogen molecule right? It is floating in our bloodstream, we conjugate it, we bind it to a protein, to escort it out of the body. It’s kinda like, hey guys in the night club, whatever rock and rowdy, security guard comes up, like puts the guys hands behind his back and like escorts him, out of the club, right? That’s kind of, when you conjugate, think about as putting- err- handcuffs on that rowdy hormone. And de-conjugation is just someone coming around with a handcuff key, and uncuffing each person, right? Think- that’s what’s happening with dysbiotic bacteria… dysbiotic bacteria, bad bacterial overgrowth, increases beta-glucuronidase, then we have the- the handcuffs, are taken off the hormone, and they can be rowdy again. So those are the big 3 ways that can affect that.

Okay, excellent. Any other questions, feel free- uhm, feel free and chime in. I’m- I’m more than like- I’m more than willing to answer any more questions. Okay. I think we hit all the major things here. Try to think of anything else we can do. Pa-pa-pa-pa-pa, awesome… Tssssss… ‘Kay. “What’s a good mindset to have when you are feeling hard bowel, and of crohn’s flare up right now?” So, ob- obviously, gut issues can affect hormone health too, right? So question is, how did it happen? I want to feel like I’m in control of the vicious cycle. I wanna know what the heck happened. So, I wanna look back and at least gain control over how I gotten into this flare up. Maybe the first thing I wanna know. And the second thing is what actions are you gonna take to get out of that flare up? So, feel free and check video 2 to 3 weeks ago on how to, you know, reverse an autoimmune condition flare. Take a look at that video. I go over a lot of good steps that are needed to- to be addressed.

Uhm, “Is fatty liver curable? What supplements would you recommend to help?”. So, yeah, it is, I mean, it’s typically gonna be a combination of insulin resistance. And insulin resistance has a major effect on female hormones. How? Because high amounts of insulin, are going to up-regulate specific enzymes that can increase androgens in women. So that can really throw off androgens, and then of course high amounts of androgens can- can mess up proactive, and prolactin can screw up uhm, estrogen and progesterone, right? So, this is a really, you know, concerning thing. So, high fructose, corn syrup, insulin-resistance are gonna be the big things that are going to cause that.

Uhm, “Thoughts on IF in regaining cycles, avoiding IF until cycle returns”. So, uhm- typically, what I would recommend, is that you do not engage in any intermittent fasting until you get your hormones back and under control. Not eating food for a long periods of time can actually be a stressor on your hormones. ‘Cause we need nutrition to run our metabolic systems. But if you are more stressed, it- it may be too much stress on your body avoiding these foods, these nutrients. ‘Cause then, longer periods of time may cause your adrenals to make more cortisol, and adrenaline and gluconeogenesis to regulate your blood sugar. The more stressed you’re at, uhm- the more stressed you’re at, the better you’re going to absor- the more stressed you are, the more gluconeogenesis, the more you’re gonna rely in other hormones to pick up your blood sugar. If those hormonal systems are weaker, you’re essentially gonna need more of those other systems to pick it up. Now, by eating and stabilizing your blood sugar, that’s gonna take stress off those hormonal systems that are weaker, and give them the chance to get stronger. It’s kinda equivalent if you break your ankle. You walk around on crutches for a bit, the goal of walking around on crutches is going to be to take weight off your ankle so it can heal.

Alright, excellent. Very good. Uhm, “Can low progesterone in ladies cause low libido?” It definitely can. Low progesterone can definitely cause, uhm, low libido in ladies. Uh- lot of times it’s just the estrogen dominants that starts to pick up, that can be the big issue.

Uh, Samuel writes in “Hey doc, been drinking a little more alcohol recently due to football games and hunting season, seems to have messed up my circadian rhythm a bit. Uh- what would you recommend for a reset?”. Uhm, more than likely, I would just stop with the uhm- stop with the alcohol kind of down a bit. You could do more vitamin-C and more sulfur amino acids, uhm, to help your body heal.

Excellent. Uh, let’s see here. Any other questions? Barbara Scott writes in, “Could chronic muscle pain impart of the menopause phase of life?”. Well, yeah, I mean, it definitely could. I mean, it’s very possible that, uhm, your adrenals are weaker, and then that’s gonna help- that’s gonna impair your body’s ability to manage inflammation well. It’s very possible. Uh, a lot your hormones have really good anti-inflammatory fats-progesterone estrogen, it just depends on what the root cause is. Did it happen from food? Did it happen from… uhm- stress? Did it happen from poor sleep? So, I wanna get a- a window in what the heck is happening there as well.

Okay, excellent. Let me keep on rolling here. Uh, “Can a hair analysis tell you a lot of accurate info?” Uh, I think a hair analysis can potentially give you some good info, the problem is, it’s all downstream information because all those nutrients that get into your hair, the half that come in through the gut. So if you have impaired gut issues, that’s going to affect what’s in the hair. So if people are looking at the hair, they’re looking at all these different mineral ratios in the hair, but if we have a gut issue, I consider that to be a lot more upstream.

Uh, “What’s the best way to balance out estrogen and progesterone in ladies?”. So, off the bat, uhm- you gotta at what the underlying reason is. Is there toxicity issues, number 1? Is there uh, absorption issues in the gut, number 2? What’s your adrenal strength at, number 3? How is your hormonal rhythm, number 4? And then I also wanna look at just uhm, you know, exposure to conventional, uhm hormones in the food. Those are all gonna be big ones, they’re off the bat.

Ugh, let me just see if I can continue to do that. “Tom Brady’s a beast last night”, not in- actually, all I had during the game was one kombucha, during the game, I got some keto-cups which are like one gram of sugar, uh- coconut, like peanut butter cups but that uses coconut oil instead. And then I had a pizza which is a cauliflower crusted, and then I use the dial almond cheese. So that was the big one that I had there.

Uh, “What would you recommend to naturally treats- treat sinus-headaches brought on by cold?” So, if you go to my site, and look at recommended products, justinhealth.com/shop, and then you look at recommended products. I have a couple of links to amazon products that I like for that. I like either a combination of the nasaline or a sinus- just injector, and essentially uhm, the Xlear Sinus Rinse. I think that works really good. The NeilMeds, good but the Xlear has a lot of the xylitol in there, which is great at killing different kinds of bacteria and also flushing things out, and it’s really helpful with that post-nasal drip as well.

Uhm, I think we hit a lot of good things here. JACK ATTACK writes in, “How do you feel about citrus pectin?”. Well on the context of hormones and peri-menopause, it’s really good at binding up a lot of these metabolized hormones that may have a problem getting escorted out, and it kinda puts the handcuff back on these hormones to help it escort outside the- of the body. So I think it really helps with detoxification of hormones. Thanks Jack, appreciate it.

“I’m an active 30-year-old male on a paleo diet suffering from bloating, loose stools every morning, find myself wanting to eat more starchy vegetables for energy.” Yeah, so I mean, that’s kind of a broad statement, but in general, I would look at the gut and figure out what- uh, the next step is there because the gut needs to be addressed.

Okay, try to keep all questions related to the topic of peri-menopause. Uhm, that’d be super helpful for me so I know what’s going on. ‘Kay, very good… Anything else guys? What else is going on? “What cauliflower crust pizza did you do?”. It’s a local place by my house that- that does an organic cauliflower crusted pizza, I’m not sure the actual brand. Uhm, and I did the diet cheese. So it’s kinda  lower carb too which is nice, so, I don’t get all bunch of a carbs either, feel pretty good afterwards too which is nice.

Alright guys, hope everything’s going well. Make sure you guys subscribe over to my thyroid reset summit, thyroidresetsummit.com, we’re going live in a month. We got a whole bunch of free stuff I’m giving out as well. I’m giving out the first like, 25% of my thyroid book. So, really excited for that get out. Hopefully it’ll provide a lot of great information. Everything I try to put out there s- I wanted to be action-oriented, so you guys can use it to actually start getting better. I help more people through my content than I actually do in person. Obviously, you know, having a personal relation, if you can’t substitute that, but this is a great way to get good information out to people here. So, make sure you sign up.

“Best lab to discern HA versus early menopause?”. Uhm, can you define what HA is? Uhm, much or- I mean, it’s probably something very common. I just- give me what that meaning is there…

Uhm, “What’s the difference between ox bile and bile used by conventional docs…”, uh- I think you mean “urso… “, uh- I’m not sure how you pronounce that – ursodeoxycholic acid. So typically, a lot of bile- ox-bile’s typically used as a bile salt supplementation when they take it from oxes or- I think bovine sources it sounds like, and they’re using that supplement as wise. Now, my line and Liver Supreme, we will use bile salts, we will use beet roots, we will use… uhm- french tree, or ___[24:47], things that are really supportive for the liver, supportive for the gallbladder, thinning out the bile, and then we’ll also help provide uhm- extra bile as well because if we can’t break down our fats, typically we’re gonna have a hard time breaking down our cholesterol, right? And if we can’t break down our cholesterol, that’s gonna really hurt our hormones. This is a really important question ’cause if you’re dealing with peri-menopause, this may significantly affect your hormones not being able to break down good quality fats.

Uhm, so- “Hypoth- hypothalamic- hypothalamic amenorrhea versus early menopause?”. Okay, so amenorrhea. So amenorrhea is like you’re still in that cycling age, it’s premature, you’re not having your period, okay? I have a woman who is 40 years old, uhm, this last couple months, started to get her period back. I see that happen many times, she wants to have a second child. Her period’s back for the first time in two years. Why does that happen? It’s a combination of typically poor gut issues, you’re typically under- you’re getting underneath nutrition, and it can be a combination that you’re not eating enough, or you’re not breaking down and absorbing enough. And then of course, all of the hormonal stress that compound for math, ’cause of course that creates adrenal issues, and that creates female hormone issues, and that detoxification issues ’cause if you don’t absorb, then you can’t run- put the nutrients in and run detoxification systems as well. Uh, so best labs to discern that, I mean, you wanna run a high-quality month-long test, and then also want to run some blood work and also some uhm- some adrenal testing as well. So you’d wanna dig in, find a good functional medicine doc to get that set up for ‘ya.

Oh, great to hear Irma, glad you’re registered, awesome. Uh, another great question just came in here. Try to keep it to the female hormones today guys… Uhm, “If I see anything remotely sad or happy tears, is that an estrogen issue? Will that affect gut health?” So, it’s hard to say, is this a- a guy you asking this question or female? Uhm, but, yeah, definitely, hormonal imbalances can affect the emotions. And you know, it’s gonna be- you’re gonna be looking for that change in emotions, maybe more emotional’s typically what you’re gonna see, but yeah, that can definitely have major effects on your emotions as well.

Nora writes in. Hey Nora, “Got acne around my jaw since June 2018. Last consult you asked if I had started doing anything different around that time but I didn’t recall. Later I found I re-introduced some thyroid support for hypothyroidism around that time. Since tests show no more hypothyroidism now, is it okay to stop the ‘Thyro balance’?”. Uhm, so in general Nora, we’d wanna make sure that we’re testing your hormones on the thyroid side, and as you’re dropping that down, we’d wanna make sure that your hormo- your TSH stays within a good functional range, as well as your hormones stand a functional range. So, it’s not something you’d wanna just drop out by itself, you’d- you’d wanna test you, and make sure as we drop it out, there could be, you know, that you’re doing good there. And then regarding any jaw acne that happens, I mean, we’d want to make sure number 1, insulin is okay, right? Insulin’s good. Uhm, ’cause if you’re doing too much insulin that’s gonna drive more androgens and then that’s gonna activate the sebaceous glands to make more oil, and that can cause the acnes. So we wanna make sure insulin’s good, wanna make sure detoxification’s really good. So- and for me to add in more sulfur amino acids and detoxifying support to run those systems, that’s good. Number 3, potentially various fibers to help bind up some of these junks so it gets or- escorted out your gut better, and then I would say number 3, if we’re still having issues you may wanna add in some prostate glanding support like black currant seed oil, and email my office if we- if we-  I don’t have your protocol up in here in front of me yet, so when patients ask me about questions here, I- I may be having some incomplete info to go off of, so if we haven’t added any black currant seed oil, we may wanna do that to help with the prosta gland and then some help with the jaw issue. And the next thing will be to- to retest your hormones with the DUTCH test to look at also how you’re metabolizing your estrogens to make sure that’s getting better. But don’t adjust anything until we chat.

Yeah, vitex is gonna be a great hormone- a great herbal support, A.K.A chastry, that’s gonna be really good at helping progesterone balancing for sure, really good.

Uh, “After getting through menopause does one need to stay on additional hormone help continually through life?”. It really depends. So what I recommend is get all your hormones symptoms under controlled, number 1. Test your hormones, make sure your adrenals and your female hormones are relatively good, uhm, from lab-testing standpoint based on your age. And then I recommend gently tapering down your hormones and see how well you do. See if you can keep your symptoms, your menopausal, se- was under control, sleeping good, your mood’s good, vaginal dryness is okay, brain fog’s good, and if you can maintain that benefit while dropping that bioidentical hormone support, that may be an option but Barbara, you’d have to deal with that at a consult, and continue to monitor that and keep that dial on going, but that’s a great question.

Okay, great. Uhm… just kinda kind of- come in here guys if I skip your question, don’t take it personal, tryna go to the questions that are most pertinent to this conversation. Zoe-Holistic writes in, “Would you be worried about a 54-year-old woman, still cycling and ovulating? Would you recommend supplementation as a- oestrogen is very high”. It just depends if you’re 54 and you’re still cycling and- and- the cy- cycle’s relatively stable and lengthen, PMS-wise, I wouldn’t too wor- I wouldn’t be too worried, I wanna know more about your parents and this is something that your sisters or- aunts- aunts, and/or mom or, you know, mom went through as well, our grandparents went through? I wanna know a little more about the history. And doing some testing, right- I think would also be good just to see where your levels are at, I think that’s a really good thing. I’ve- I typically more concerned Zoe with people, uhm, prematurely going into menopause, that’s my bigger concern, that’s the thing I’m seeing these days. But I think it’s always good to get tested.

“Is there a connection between hypoglycemia and adrenal fatigue?”, yes! Great- great question Olga. I see a lot of low-blood sugar symptoms’ really being a big stressor on the adrenals, and then that can create a lot of lower progesterone issues, creates a lot of stress. I definitely see that being a concern.

“What is the average acceptable age for menopause?”, typically 48 to 51-ish.

Ik O, “Best test for progesterone levels?”. I mean, you can run a typical progesterone blood test, you know, we like to be at least 10 to 15 on that, around day 20 of your cycle, right? Considering your cycle being like 26 to 30 days, and/or like a- a good high-quality DUTCH complete panel that we’ll run around day 19 to 22.

Nora, you’re totally welcome. So, email my office if you need that black currant seed oil, I’ll put you on 2 capsules of that twice a day if your skin is still having some issues. Two caps, twice a day and I have a couple recommended brands.

Jessica Lynn writes in, “Does liquid vitamin-C raise estrogen? I read studies say that there’s a connection”. I’m not sure that it would raise it. I will typically give vitamin-C in fiber to actually help with estrogen detoxification, so I don’t think it would raise it, maybe there’s some modulate- maybe there’s some modulation effects, or may help modulate it but I couldn’t imagine it actually raising it, like taking maybe uh, hormone would.

“My kidney pain by eating a honey, age 27, serious problem?”. Uhm, yeah that’s a good question, kinda little off-topic, but in general, I would be careful with the too much fructose.

“Will chaste tree help with progesterone?”. It will, it’s gonna help with LH, luteinizing hormone which is gonna help talk to your- your ovaries, and that kind of female hormone area to make more progesterone?

DesignLover writes in, “Took birth control pills for 1 year for adult acne, it worked. Now I’m 37 and it’s creeping back around the jaw line. Connection to sugar or more estrogen related? Or more cortisol? Also, hard time sleeping.” Now again, like birth control pills can help, even though you’re actually giving more estrogen with the birth control pill, it does kinda level out your hormones, so you’re not getting swings. So, I think a lot of the hormone swings can really be a big effect there so we can kind of level stuff off. But I also see, you know, birth control pills cause more issues. You can see melasma as well, which is the estrogen, kind of stimulates the melanocytes and more pigmentation, you can kind of get that pregnancy mask, while on the birth control pill, and someone that can actually make their acne worse. I’ve seen it on both sides. Is there connection to sugar and more estrogen-related, yeah, there’s definitely a big connection with sugar because sugar will actually increase more insulin. And insulin will create more ___[33:23], which will cause the bacteria to feed off of your skin and create more acne.

“My natural doctor put me on liquid vitamin-C and I’m having short cycle, 26-27 days with very light bleeding and prolonged bleeding”. Yeah, I would need more info, I’d wanna test your hormones, see where you’re at. A lot of my younger female patients will use herbs to help the signaling upstream from the brain to your ovaries and then we’ll also- a lot of times give a little bit of bio-organical progesterone, but we’ll give it in a specific cyclical augmentation fashion while we’ll taper it up and down. But we really wanna be specific in how we do that.

Amelia V writes in, ” If taking T3 you mentioned in past, needing it uh- multi-x-day due to half life. Why am I only- why am I only RX dosage for the AM?” Uhm, so, yeah, if you’re just taking T3, I don’t recommend only taking it in the AM, and like if you’re doing a Cytomel or liothyronine, you’re gonna be dropping off on your- uhm- on your T3 within 4 to 5 hours, so you definitely want to uh, not do it that way. In the thyroid re- reset summit, we had ___[34:26] on the uhm- summit talking about these exact things. So make sure you subscribe thyroidresetsummit.com, make sure you subscribe.

Olga writes in, “Can longtime use of Mirena iud cause energy problems?”. Yeah, Mirena can cause a lot of side effects. Merina is a synthetic progesterone, and there’s an iud to secretes that. So, yeah, it can definitely- I mean, my biggest issue with that is it just kind of seeps in your bloodstream throughout the whole month at least with like, birth control pills, you kinda take a reminder session, you know a 6 to 7 day reminder where you kinda- drop out your hormones and then- and then that can cause bleeding where you kinda have this steady state of hormones with the Merina, which I think’s a little bit unnatural because you don’t have any drop at all. That’s concerning, so- I always recommend my female patients if they want- uhm- an iud to try the ParaGard which is a copper-iud that’s non-hormonal.

Uhm, “‘Can’t miss’ interview from the thyroid summit? What was your favorite interview?”. It’s a great one, I’d had a lot of a really good interview. It’s hard to say which one was the best. It really depends on the topic. ‘Cause we’re really connected the thyroid to the gut, thyroid to the emotions, thyroid to the adrenals, thyroid to fertility, thyroid to female hormones, thyroid to- even male hormones or gut inflammation, or gluten, or autoimmunidase. So those, you know, it- it was so many different areas, it’s really hard to say.

Paul writes in, “In menopause, how to stop hot flashes?”. Well, a lot of times, the hot flashes can be from a lot of these upstream hormones in the brain like FSH going really high. ‘Cause think of the ovaries, right? Your brain makes hormones that talks to the ovaries to make more hormone, more female hormone. So, as the brain- as the ovaries aren’t, you know, don’t have the follicles coming in, and we’re not making as much hormone, the brain is trying to rev up the volume that talk to the uhm, downstream glands. And that FSH as it goes higher can really increase vasodilation so, giving certain herbs can really help with the signaling and help kind of decrease the volume a little bit, modulate the volume, and then giving some bioidentical hormones can also help modulate the volume as well. ‘Cause the brain says, “Hey, I’m getting a little bit more hormone in there naturally, we can lower the volume as well”, and then we deal with the herbs to help with the receptor sites too. So there’s a couple different ways that we can do it. But that’s kinda one of the major philosophies regarding FSH, and regarding a lot of the hot flashes.

Uhm, ” Is Chaste Tree something you can take to see how you feel…?”, I mean, you really want to be working with the functional med doc on this. A lot of variables when it comes to that.

DesignLover , “Is there a connection to an imbalance of hormones in women who haven’t bore any children?”. Potentially, I mean, women that haven’t born- birthed children, they don’t have that progesterone increase that happens, uhm- throughout pregnancy, so that- you that- 8 or 9 months where progesterone goes up because of HCG, that goes up significantly higher. So that may- let’s just say, you have a greater chance just kind of being more an estrogen dominance, over your- your cycling fertility time-frame so to speak, where hormone, who is uhm- pregnant one, they’re not gonna be using up the follicles as much ’cause you’re not cycling when you’re pregnant and a lot of time during the breastfeeding process. So, you’re not going to cycle through your eggs as fast. And then number 2, you’re more overall an average having a higher input of progesterone, so that has some effects as well.

Uhm, Zoe writes in, “Do you find the people with more severe menopause symptoms always have more adrenal issues when testing, is that your finding?”. I wouldn’t say always but I- ’cause it’s- it’s-  I don’t- I’m not a big fan of absolutes but I would say yes. I would say on average, that is a significant correlation, more menopausal issues have more adrenal issues. And also, peri-menopausal issues, more adrenal issues, and I’ll even go one step further, cycling female issues, right? Definitely adrenal issues.

Uh, Amelia writes in, ” I’ve heard it takes one month to re-balance cycle for every year you haven’t had one?”. Yeah, that pro- that makes sense, I definitely agree with that, I mean, I typically see a major rebalancing in a- in a woman’s cycle within 6 to 12 months. And a major rebalancing is- I thi- I would s- call that, is about a 50% improvement. Alright, and then from there, we continue to compound that improvement month after month.

“Can someone with copper toxicity use a copper iud?”. Yeah, I mean, you can just make sure you’re doing extra zinc, put some extra zinc in your supplementation regime to help balance out the copper toxicity. That would be a good helpful approach ’cause you have the paragard or- is a copper iud and of course that can increase your copper levels. So you gotta be careful with that. You gotta weigh that out with your doc and see if you are really are copper sensitive. I have some patients that cannot do a paragard copper iud, they just can’t do it. Uhm, some can do it great and they have no problems. So you really gotta weigh those options out.

Uhm, “Can peri-menopause cause weight gain in the stomach? I’m 49 years old, no period for 7 months, gained 20 lbs. in the stomach in the last year and I can’t seem to lose it, is it just from unbalanced hormones?” So, remember, a lot of uhm, adrenal issues connect to peri-meno- menopausal issues. And a lot of adrenal issues are coming from cortisol imbalances. And cortisol has a direct effect on your tummy through just cortisol itself, the stress hormones can aff- affect the gut, and also through more sugar being released which can have an effect in insulin which can also affect your tummy. So, adrenal issues, have a major effect with cortisol, and also plug in and connect to insulin as well. So, great questions there.

“Do you think women with polymorphisms in COMT and MTHFR should not take the contraceptive pill? Controversial topic”, I know. Well, I know, in general like COMT like uh- catechol-O-methyltransferase. So when you see, uhm these types of issues, you may have issues with various adrenaline and just being able to deal with stress because these catecholamines are- like, you know, basically your stress hormones, your stress neurotransmitters. And MTHFR typically is gonna have a major effect on folate and then also affect B-12 and can affect methylations. So, uh- birth control pills deplete a lot of those nutrients. So yeah, I think what you’re saying is a very valid topic ’cause those issues can really have an effect on those nutrients. So if you are taking the pill, uhm- you really wanna make sure you’re supplementing with extra methylating nutrients, magnesium. In my line we’d recommend like B-vitamins synergy which has like the extra-activated folate, activated B-12, activated B-vitamins, and also a good multi on top of that, with magnesium and calcium, other important minerals that tend to get depleted.

Uh, “What would cause early spotting and irregular monthly cycle?”. That’s gonna because by typically lower progesterone or progesterone dropping out too soon in your cycle.

“Are there other conditions that cause hot flashes after menopause?”. Uhm, hard to say. I mean, you could- you may notice issues with blood sugar. Blood sugar ___[41:27] may get problem. A low thyroid, you may see some issues with that like if you have autoimmune flares on the hashimoto’s side. So yeah, there’s some potential connections there.

“Thoughts on carb cycling/keto for women with hormone imbalances? Ideal balancing diet?”. So, a lot of women do go with keto initially because they have insulin-resistance, and keto is very helpful with insulin resistance. But if you’re insulin-resistance is dialed in and you’re doing good with your blood sugar, some women starts to do better as they add in a little bit of safer carbohydrates, starches, squash, sweet potatoes, and they may even be better doing it cyclically. What does that mean? You’re kind of lower-carb keto for 2 or 3 days and maybe you have a sweet potato for dinner with your veggies and your meat. So, that I think is- is a very valid point, and I see that clinically.

Uhm, let me see here. Any other questions on hormones? I think we hit everything guys. Give me a thumbs up, give me a share, I appreciate it, make sure you hit that bell. People magically just go off my subscribe list if the bell is not hit. So make sure that bell’s hit, so you get all my notifications. Appreciate, uh today’s chat. Hopefully en- you enjoyed it, if you enjoyed it, give me a comment below. Let me know what you think. Any questions related to the topic, I’ll be back in and address them in future podcast or- we’ll respond here and I’ll look forward to connecting with you guys tomorrow, for a live Q&A.

You guys have an awesome day, and uh, go Patriots! Take care. Bye.


References:

https://thyroidresetsummit.com/

https://justinhealth.com/

Xlear Sinus Rinse Kit

SIBO, Yeast Overgrowth, Mood Issues & More – Podcast #169

Your gut affects your health in a variety of ways, and it’s not just about digestion. The health status of your gut can influence the immune system, your weight, and even your mood! In today’s part-podcast and part-Q&A video, let’s join Dr. Justin Marchegiani and Evan Brand as they talk about gut health and how it affects us as a whole.

Watch and listen as they discuss topics like Small Intestinal Bacterial Overgrowth (SIBO), yeast or fungal overgrowth, weight gain and weight loss, and even the link between your gut and your mood swings. So many people are diagnosed with SIBO, in fact, Dr. Justin says that almost 90% of his patients are suffering from this condition. Learn how to manage your gut health by taking the right supplements, eating the right foods, and preventing issues from wreaking havoc on your overall health. Watch this video for more info!

Dr. Justin Marchegiani

In this episode, we cover:

02:30   SIFO is Definitely an Issue

05:20   Conventional Treatment of Candida and SIBO

07:19   Urinary Tract Infection

10:00   Treating UTI by Just Hitting the Gut.

21:36   Top herbs for Candida Overgrowth

Youtube-icon

Dr. Justin Marchegiani: Dr. J here in the house, with Evan Brand. We’re gonna do a live Q and A call. We may talk about some topics near and dear to us, what’s trending. And then if you guys want to come in on the side and ask any questions, feel free. We are here to serve. Evan, what’s cooking, man?

Evan Brand: Hey. Uh— not too much is cooking but I’m drinking some apple cider vinegar drink. Good old Bragg’s uh— with some cinnamons. So, that’s good. This is a good— like tummy tonic, and there’s a small amount of sugar in here but— Hey, I’ve got Stevia extract in here, some ACV, some little bit of apple juice. I could probably make this myself, but it’s so convenient for two bucks to go buy one of these and just have a nice little tonic.

Dr. Justin Marchegiani: I know. Totally. Just that convenience aspect is really nice. I like the lime one. The lime one’s really good, too. IIt’s only sweetened with Stevia.

Evan Brand: Oh, that one doesn’t have sugar.

Dr. Justin Marchegiani: Yeah. That one’s a good one.

Evan Brand: Oh. Yeah. I didn’t know that…

Dr. Justin Marchegiani: Love it.

Evan Brand: existed.  

Dr. Justin Marchegiani: Wow, man.

Evan Brand: Well, I did an interview uh—

Dr. Justin Marchegiani: Now you know.

Evan Brand: I did an interview this morning uh— with my— for my summit, and it was all about SIFO, so I figured maybe we could chat about that, like Small Intestinal Fungal Overgrowth are what we’re seeing. You know SIBO is such like a hot topic, but people aren’t really talking about SIFO, and you and you and I are seeing so many people every week. I’d say, it’s what— 90 percent of the people have yeast overgrowth?

Dr. Justin Marchegiani: Yeah. I think, when we look at yeast, for instance. You know, we do a typical SIBO test, which looks at Methane and Hydrogen gases, which are— you know— You give a sugar s— solution via lactulose to the per— person, and that sugar’s indigestible to the body, except certain bacteria that are dysbiotic. And when those bacteria eat that lactulose solution, they spit off Methane of Hydrogen gases, depending on wha— what bacteria they are. And that Hydrogen can either disrupt and cause diarrhea or increase motility, or can cause decrease motility via Methane, so— Of course, we see it with various gases indirectly. We don’t know the exact bacteria, but we know that those gases are there because the exhaust created by it. It’s kind of like, you don’t know a car’s in the garage if it’s not there, but if you smell the exhaust that it left a minute ago, you can kind of tell, right? So, it’s kind of like that. And of course, people can have— or patients can have symptoms in their gut via fungal overgrowth. And, symptoms can overlap pretty well, so you may have a fungal overgrowth or something else happening and you may think it’s a small intestinal bacterial growth. You may come back on the test with nothing in that area, but we may do some other testing that shows a fungal overgrowth is present.

Evan Brand: Yeah.

Dr. Justin Marchegiani: So, SIFO’s definitely an issue.

Evan Brand: Yeah. So let’s— let’s go through symptoms a bit. What if somebody know if— or expect that they have SIBO or SIFO? There’s gonna be the bloating, could be fatigue, could be anxiety, could be brain fog, uh— could be food cravings, sugar cravings could be possible. Uh— I mentioned the mood issues, like anxiety, because most people don’t think about it, gut being a cause of anxiety. But it is. And when I had gut issues, I had anxiety. I lost weight. I had brain fog. I had fatigue. It’s all because of my infections.

Dr. Justin Marchegiani: Hundred percent. And a lot of people who have gut issues, right? They’re gonna have a lot of mood issues or energy issues too. It’s very rare that someone only has gut issues. Like, they could have diarrhea, bloating or gas, or indigestion, or GERD, or acid reflux, or gastroparesis with their food, just sits in your tummy for a long time. But it’s very possible that you could just have mood issues, uh— brain fog— With fungus, it’s common to have joint pain. It’s common to have brain fog. It’s even common to have anxiety too. Uhm— the yeast, kind of metabolic products in the gut, uhm— when they metabolize, they can spit off acetaldehyde. Acetaldehyde can then create a compound called salsolinol. Salsolinol can create apoptosis in the midbrain, where it— it can actually kill off some of the uhm— substantia nigra cells that produce dopamine— s, of course, you know, chronic yeast issues, severe yeast issues, but could potentially create more neurological issues due to all the toxic by-products.

Evan Brand: That’s a trip. Now, I know saccharomyces boulardii. We talked about it. We use it for the saccharomyces could do two things, maybe you colla— collaborate on this a bit for the saccharomyces as one, gonna help to crowd out the yeast, but can also kill the toxins that Candida’s producing. Can you speak on that? Do you know what I’m talking about?

Dr. Justin Marchegiani: Yeah. I mean, yeast, Candida can also produce [stutters]— As a by-product, they’re gonna produce mycotoxins, right? And these toxic by-products can disrupt digestion. Uhm— they’re also— you know, acetaldehydes, a stressor that’s produced by the Candida that I mentioned earlier. And Candida’s one type of yeast. You know, they’r— you can have, you know, the Rhodotorula species that— that the cal— Candida albicans, as the Candida of everyone refers to. You have the Geotrichum candidum. You have uhm— these species as well. So, of course these things can cause similar symptoms as SIBO and they can create toxic low because of the how it disrupts toxicity, how it disrupts uhm— digestion. You need nutrients to run our detox pathways. It can create this mycotoxins, which then have to be processed by our detoxification system as well. And of course, it can stress out the immune system because 80 percent of our immune cells live in our gut and it can create more permeability with the gut, i.e., leaky gut, which then gets the immune system fired up. Which is kind of like leaving the uhm— the faucet on in your guest bedroom that you never go into, and your water bill’s sky high that month.

Evan Brand: Yep. Well said. So, let’s talk about treatment a bit. I mean, some of the options that we use, conventional docs. Maybe let’s chat about that first. I mean, we always go straight to the functional medicine piece and assume that people understand that. But I don’t think many people understand what and how poorly conventional medicine treats Candida and bacterial overgrowth type issues.

Dr. Justin Marchegiani: Well, most of the time, conventional medicine’s gonna, you know, typically laugh at your face when you talk about Candida. And unless you have— number one, you have some type of skin-oriented rash, like a tinea versicolor, some kind of seborrheic dermatitis. That’s apparent on the skin, right? It’s like, it’s there. You can see it. It’s apparent they’ll recommend some type of antifungal cream, and they won’t ever look deeper in the gut, which tends to be the root of where it comes from. Or there’s like a vaginal yeast infection or there’s some kind of thrush, where there’s a white coating around your mouth or tongue. So, unless you have those two or three things, for the most part it’s not gonna be picked up. And the Candida like we mentioned can create a whole host of issues: fatigue, mood— It can create things that are none digestive. It can create things that are digestive. I already mentioned. And if you’re going to your conventional medical doctor, it’s typically not gonna be picked up. We can even see it via antibodies, too. So, sometimes people will do a stool test but we’;; actually see the candida via the antibodies. It’s hard to pick up so, we’ll always use clinical symptoms too. Oh, the other one was a fungal tell— fungal toenail.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Like the yellow kind of thickened discolored toenail. That’d be the— the fourth one. [crosstalk] Mouth, nose—

Evan Brand: What about on the fingers, too? I’ve seen people with like a ye— a yellow nail, where it’s like…

Dr. Justin Marchegiani: It’s the same.

Evan Brand: …falling off.

Dr. Justin Marchegiani: It’s the same thing, right? Toenail and fingernail is the same kind of thing.

Evan Brand: Yeah. Okay.

Dr. Justin Marchegiani: Mp— that thickened type of fungal things we see on the nails, on the skin, Uhm— typically, on the mouth, and then typically, vaginal. And let’s say number five would be kind of like a uhm— seborrheic dermatitis, or like a cradle cap, or like a dandruff. It’s kind of in that same fungal category. So, five big ones: hair, mouth, vaginal, skin, nails…

Evan Brand: Got it.

Dr. Justin Marchegiani: …toe or finger.

Evan Brand: Yeah. So, let’s talk about UTIs for a bit. Now, when you hear about a Urinary Tract Infection, a lot of times, this is affecting women. Is that bacteria plus Candida [crosstalk] at the same time?

Dr. Justin Marchegiani: Typically— It depends. Typically, it’s gonna be bacteria. The— the number one way you can figure it out is typically bacterial vaginosis. We’ll have kind of a fishy odor to it. So, it’s gonna a little bit fishy, in women. No, it’s like— okay, it’s apparent something’s going on down there. Yeast infection, typically is not gonna smell like that. It may smell a little bit yeasty, almost like a buri kind of smell, but it’s not gonna have that kind of fishy odor smell. That’s the number one. Both are gonna have discharge. [crosstalk] Both are gonna have discharge, typically like you know, kind of a cottage cheesy kind of fim. Uhm— you know— We’re getting pretty graphic here but hey, this is— this is what we do, all week long. So, of course, that’s the big way. And then, typically, the UTIs can affect primarily the urinary tract, right? Bacterial vaginosis involves more the Gardnerella bacteria. Uh— the UTI is more gonna be the E. coli bacteria. And then, of course, yeast is gonna be more like your Candida albicans kind of thing. So, of course, like if it’s a UTI, you know, you tend to feel it. It tends to hurt more when you pee. A little bit of pain or stinginess when you pee; bacterial vaginosis, probably not as much. Maybe just itchy. And the big— you know, dividing factor would probably be the odor, as how you would know.

Evan Brand: Okay. And then [inaudible]—

Dr. Justin Marchegiani: Of course, you can get a culture. You can get a culture, right? You go see your doctor. They may do a culture, but in terms of treatment for bacterial vaginosis, we may do kind of an herbal formula, mixed with apple cider vinegar. And we make it like a douche applicator and flush that area out for a week or two. And then, we may throw some probiotics in, internally via the mouth and intervaginally to help shift the pH. Typically, getting more acidic pH makes it harder for that bacteria to grow. Obviously cutting out the refined sugar and the junk of your food, too. With yeast, similar thing. We have some Boric acid or suppositories that we’ll use. The help will also get the probiotics going. Cut out the refined sugar. And then for UTI stuff, we’ll typically use some Silver. We can use some D-Mannose powder. We can use Uva Ursi herbs. Uhm— we can do apple cider vinegar, lemon juice. These are all really good things that we can do to help acidify the p— acidify the urinary tract. Also we can do cranberry juice extract, unsweetened organic. We can also do some organic cranberry pills as well. That has a big shift on the pH in the urinary tract, which then starts to starve them out because they— they tend to not live as well in that nice acidic environment. They tend to grow more in an alkaline environment.

Evan Brand: So, let me ask you this. Could you successfully treat a UTI just by hitting the gut?

Dr. Justin Marchegiani: Uhm— you could. Uhm— again, like some of the things we’d want to do is to want to make sure we have some of those herbal metabolites make their way out the vaginal, you know. I mean, typically UTI it’s gonna go out, right? It’s gonna head some and go out, and so the urinary tract will be hit. The question is, “Will the vaginal area be hit.”  Obviously, for peeing it out, it’s not gonna be hit. It’s close in that area, but more than likely it’s not gonna hit it. That’s where you need some kind of an herbal douche formula to topically get in there. Same thing with the yeast. So, yeast, you kind of want to top like in there with a suppository. BV get in there uhm— with a— a flushing type of herbal mechanism, and just make sure you’re not pregnant, right? ‘Cause the— there could be some abortifactant uhm— mechanism there if it’s getting too close— you know, up the vaginal canal. And then, uhm— number three is the UTI that we could do internally, and we could flush out that way.

Evan Brand: So, could you go— I mean are there like professional grade herbal douche blends, or is that something you’ve got to piece together yourselves? Like, does the store-bought version exist?

Dr. Justin Marchegiani: Yeah. I have one that I use that works really well. It’s good to call herbal douche formula, and that we should choose an applicator when we mix— mix it with some apple cider vinegar, like the instruction’s say, and we flush one— one or two times a day. [crosstalk] I’ve got to shift the diet. I’ve got to shift the diet. Typically, it should do a— a really good probiotic intervaginally, as well, that kind of help shift the pH and shift the microbiome there.

Evan Brand: Is there a brand for that?

Dr. Justin Marchegiani: Yeah. I like one by Wise Woman Herbals.

Evan Brand: Okay.

Dr. Justin Marchegiani: [inaudible] … for the herbal douche formula, and then the probiotics will typically do, you know, my Probio Flora or will do a Woman’s formula. But typically, the Probio Flora is enough as well.

Evan Brand: Cool. Okay.

Dr. Justin Marchegiani: Probio Flora too is uhm— the Phage in there really helps kill uh— E.coli too. So, if it’s any UTI stuff going on too, that could also help with that too.

Evan Brand: I’m gonna bookmark that. That’s really really cool. And this— I feel like the douche is something good where if you’ve got like a resistant infection or something that just keeps coming back. Sounds like that would be a good thing to add in.

Dr. Justin Marchegiani: Yeah. And then, typically though, even if we ever— let’s say, we do topically hit that area, we still want to make sure we systemically treat things too. Like, we would topically hit something ‘cause you want a faster results.

Evan Brand: Right.

Dr. Justin Marchegiani: Like, let’s say, there was a fungal nail, right? And maybe really hard to get rid of that fungus on that nail if we just hit it to the gut. So, we kind of want to hit it from both ends. So, we kind of want to put that critter between a rock and a hard place. Make it so it has nowhere to go.

Evan Brand: So, do you add apple cider vinegar, too. That’s— I know it comes [crosstalk] west.

Dr. Justin Marchegiani: Yeah. We’d add it to it.

Evan Brand: Okay.

Dr. Justin Marchegiani: Make it says like add six ounces of apple cider vinegar or something. If you read the jo— instructions on how to mix it.

Evan Brand: ‘Cause like in ingredients, it says it’s in a base of ACV. So, I was just curious.

Dr. Justin Marchegiani: Can you read the in— Can you read the instructions?

Evan Brand: Yeah. It says, “Add one tablespoon of concentrate per six ounces of warm water.”

Dr. Justin Marchegiani:Per warm water?

Evan Brand: Yeah.

Dr. Justin Marchegiani: Got it. Yeah. So then it’s the warm water then. So, the apple cider vinegar’s already in it. SO, we will just add that to the warm water.

Evan Brand: That’s really cool, man. I learned something new everyday.

Dr. Justin Marchegiani: That’s it.

Evan Brand: Wow. Well, thanks. [crosstalk] Let’s look at some questions and see what we’ve got here, digestively. Uh— Evie ask you a question, “Dr. J, I’ve been taking your Digestive Supreme and HCL. They’re helping a lot. Thanks. Is it okay to take for a long time or should I stop after some time?

Dr. Justin Marchegiani: So, typically, if there was an infection, we want to get rid of the infection and then we can taper it down. And then, the rest is gonna be based upon you. So, if you’re under a lot of stress during the day, you know, then we may want to take it during stressful period. If you’re eating food that’s maybe a little bit questionable, we want to save it for that. So, get rid of the infections. Get rid of the internal stress that’s causing the issue. You know, as long as your diet’s on track and the stressful environment is kind of under control or you’re not hydrating so much during the meal, then I think it’d be okay to reduce the consistency on that, for sure.

Evan Brand: And I— I— I’ll throw my two cents in.

Dr. Justin Marchegiani: Yes.

Evan Brand: I cycle on and off enzymes, personally.So, I just got my Stool testback. I showed up with some gut bacteria, showed up with the cyclospora parasite. So, needless to say, I’m back on enzyme ‘cause I’m clearing out these infections because the last thing you want is undigested food particles feeding the bugs. Like Justin mentioned, if you’ve got an infection, something that— like H.pylori could be suppressing stomach acid. You know, that’s undigested food that’s going straight to the bad guys. So…

Dr. Justin Marchegiani: Yeah. And I noticed myself. I was just having a— like uh— looser stools for the last few weeks only after coffee, and it was just— typically, was a different consistency. So, I just start on. I used to hit my GI Clear 4 and Para 1 up, and I noticed that it did start to solidify again even after coffee. So, I’m gonna be doing the GI Map Test at the end of this month…

Evan Brand: Good.

Dr. Justin Marchegiani: …and see what at.

Evan Brand: Well let’s go through your results when they come.

Dr. Justin Marchegiani: Yeah.

Evan Brand: It’d be a fun show.

Dr. Justin Marchegiani: Yeah. I’m excited. Then also uhm— I saw your test last night. I saw the increased steatocrit on yours…

Evan Brand: I know.

Dr. Justin Marchegiani: …and the increased beta-glucuronidase. So, definitely hitting it with the antimicrobial herbal stuff, maybe adding in some extra bile salts or lipase in there too would also help.

Evan Brand: Yeah. I appreciate it. I’m gonna uh— I’m gonna do that, and then also, I’m gonna add in some milk thistle too. Try to get that glucuronidase down.

Dr. Justin Marchegiani: Yep.

Evan Brand: No probiotics can do it, but I think I rather probably do both.

Dr. Justin Marchegiani: Well, yeah. I mean, glucuronidase is gonna be— if you kill the bacteria, that— that will go down, too.  

Evan Brand: Okay. That’s cool.

Dr. Justin Marchegiani: You can just throw in some extra charcoal to help bind that up too.

Evan Brand: Okay. Also, uhm— we’ll have to chat but uhm— where we’re getting our Para 1. There’s also a binder that they’ve got, which is like a Fulvic acid – Charcoal mix.

Dr. Justin Marchegiani: Yeah. I’ve seen that . I think that’s good too. Uhm— I find that— you know, the charcoal’s still really good as well. So, you could do either one [crosstalk] then. I like the charcoal.

Evan Brand: Yeah. And the charcoal’s so cheap.

Dr. Justin Marchegiani: That’s the thing. The charcoal’s just a little bit more cost-effective, that’s why I like it.

Evan Brand: Yeah. You can’t beat it. Okay, [crosstalk] cool.

Dr. Justin Marchegiani: And it’s still great. I mean, it’s still— you know, you can use it for alcohol— I had— my Patriot’s play yesterday, my Tom Brady. They’re just freaking awesome, man. He used to go— and— you know, he is just like the perfect— like practitioner spokesperson for natural medicine. I mean, what he does, what his diet, and he eats basically a Paleo Autoimmune Template for the most part. He’s trying to keep inflammation down.

Evan Brand: Yep.

Dr. Justin Marchegiani: And uh— you know, he trains in a way that to support pliability and muscle length, and then which we’ll have to uhm— try to get his trainer on, man. I got to get him on…

Evan Brand: Good.

Dr. Justin Marchegiani: …and speak to him. I know. We’re gonna work on that. But yeah, he’s a perfect practitioner of all these stuff. But uhm— in regards to—- where was I going? So, we just talked about?

Evan Brand: I think you were talking about—

Dr. Justin Marchegiani: Oh, yes! I’m sorry. So, I had a nice glass or two of champagne yesterday.

Evan Brand: Oh.

Dr. Justin Marchegiani: So, I hit up some activated charcoal, and I hit up some Sulfur amino acids, and I feel phenomenal. No issues. Then, of course, I have a nice glass of mineral water in between drinks that prevents any— you know uhm— the antidiuretic hormone that’s being reduced. So, all the peeing that happen from alcohol, prevents any of those minerals from being washed out. So, that’s my little tip there.

Evan Brand: That’s cool. Uh— anybody uh— listening, watching, add your comments. We’re gonna go through these. We’ll try to answer as many that are on topic as we can. So, add your comments now. So, we’ll go through it now.

Dr. Justin Marchegiani: Yes. And we’ll hit the ones that are on topic— is— is first. And then also, give us a share, give us a like, give us a thumbs up. We appreciate it, guys. Help us grow so we can help more people like you. Your benefitting right now. Don’t keep it all to you. Let it get out there. We appreciate it.

Evan Brand: Absolutely. Uh— what’s our time on? How much time we got left with these questions?

Dr. Justin Marchegiani: We— we got five minutes. Let’s roll for it.

Evan Brand: Okay. Alright. So, we’ve got one here from Jeff. Uh— he says that he’s been taking the GI Clear 1, 2 and 5. Two caps a week for H. pylori. Yesterday was his birthday. He’s been so sick; nausea, headaches, panic attacks. How should I take the herbs on an empty tummy?

Dr. Justin Marchegiani: So, number one, I‘m imagining that because it was your birthday, you may have gone off the—

Evan Brand: Oh, oh.

Dr. Justin Marchegiani: …of the rings there, Jeff, maybe with some extra birthday type of uh— surprises or things like that. So, there could be that. Uh— number one, if we’re having some sensitivities, we need to come off the herb for three to five days, get back to base line, add them a ginger tea, and then ratchet up one capsule per day on each herbal product. If you hit the wall, meaning you start to have those nausea or negative symptoms, you  back off. Get super stable before you go to the next. And of course, if you’re having issues, take it with food, because the food kind of prevents a buffer. So, those herbs aren’t sitting up against an irritated gastric mucosa, add in the ginger and then we should probably throw in some activated charcoal in between breakfast and lunch away from food and lunch and dinner away from food. That will maximize absorption of any of the— the toxins. But dial in the dose. Don’t be a hero and push it too high and too fast. Take it with food. Take a couple of days off. And then, add it back in.

Evan Brand: Yep. Good advice. Now, the question here. Dr. J, I’ve been following your advice but not perfectly. I’ve had long term constipation, GERD, gastritis, H. pylori, bloating, abdominal distention, cramping. How can I help myself? I’ll answer this one.

Dr. Justin Marchegiani: Yes.

Evan Brand: If you don’t mind.

Dr. Justin Marchegiani: You got it. Do it.

Evan Brand: Uh— You’ve got to get tested. I know you said, “I’ve been following…

Dr. Justin Marchegiani: Uhmmn—

Evan Brand: “… meaning you’ve probably been watching Dr. J’s videos, maybe some of the stuff that we’re doing together like this. But if you’ve knocked out the testing done, then you’ve— you’ve got uh— you’ve got to do that. If you say H. pylori— if it’s still there, you’re gonna have these symptoms. So, you’ve got to get some functional medicine testing. You can reach out. Get that done. And, we’ve got to fix the bugs. You’re never gonna fix constipation if you’ve got bacterial overgrowth ‘cause those gases are gonna change the intestinal motility time. Bloating; same thing. That could be yeast, fungus, bacteria, H. pylori. We know that’s why you’ve got the GERD, because that’s suppressing your stomach acid. You’re gonna have heartburn because your body’s not gonna allow the undigested food to go down. So, get tested and then we can use herbs to fix this.  

Dr. Justin Marchegiani: One hundred percent!

Evan Brand: Uh— let’s keep going here. We’ve got another [crosstalk] question from Kitty. Uh— She’s taking the beef protein powder. That makes her constipated so she take HCL and pepsin even though it’s a powder.

Dr. Justin Marchegiani: I would say, you could try it, and see what happens. If it doesn’t work, there could be something in it that you’re allergic to so I would try a Collagen protein that’s in a peptide form and see if that shifts or changes it. ‘Cause that’s gonna be in a more broken down assimilated form. [crosstalk] So, try it. Try more enzymes and HCL, and see what happens first. And then try just a really clean— like— you know, my TRUCOLLAGEN. Try something in a collagen peptide form…

Evan Brand: Yeah.

Dr. Justin Marchegiani: …and see if that fixes it. And then, let us know.

Evan Brand: Good advice. Another question, “Hi, Dr. J. I’d like to ask you uh— how to detox from heavy metals toxins, parasites, etc., naturally?” We’ve done a ton of shows on this. We’ll continue to probably hit this topic, but just searched justinhealth.com or search the YouTube channel here for those ti— uh— those titles, and you’re gonna find some stuff. But that— that could be an hours and hours and hours conversation.

Dr. Justin Marchegiani: Totally. Yep. Absolutely.

Evan Brand: Samuel. Want to read that one?

Dr. Justin Marchegiani: Yeah. “Is it possible to overpopulate with good bacteria using probiotics? And if so, what steps do you take to balance?” So, number one, we can see it with patients that tend to have like digestive issues or SIBO. We see an excessive amount of D-lactate, which can be caused by throwing a whole bunch of Lactobacillus in with the whole bunch of dysbiotic bacteria. So, we can see that. So, number one, make sure we’re starting from a blank canvas, not a canvass full of messiness from the start. Uhm— number two, probiotics tend to be transient. They’re not gonna stay around longer than a month or so. So, they are transient. So— Number one, a good steady dose of them is gonna be fine. So, you know, two to four capsules I think is a reasonable amount, like with my Probio Flora. And I think, you know, some couple sources of fermented foods that you want to throw in a weekly, whether it’s a lower sugar Kombucha, fermented pickles, sauerkrauts, uhm— those are all good standard options that you can kind of add in. And, I think, as long as your digestive symptoms are under control and you’re infection-free, I would not worry about it. If you’re having a lot of blow or gas because of probiotics, you probably have to look a little deeper and see what’s happening with the dysbiosis or other infections.

Evan Brand: Yep. One more questions right next to that. You want to hit that one too?

Dr. Justin Marchegiani: Top herbs for Candida overgrowth?

Evan Brand: Yep.

Dr. Justin Marchegiani: Oil Oregano, Berberines, Silver, not really an herb but it’s still something that we use, uh— Clove, Wild Indigo, grapefruit seed extract; I would say those are a couple, right there. Anything you want to add?

Evan Brand: Yeah. I’d like to add olive—

Dr. Justin Marchegiani: Anything like a medicine?

Evan Brand: Yeah. Olive leaf.

Dr. Justin Marchegiani: Olive leaf, yep.

Evan Brand: Uhm— the monolaurin, the lauric acid…

Dr. Justin Marchegiani: Monolaurin, lauric acid, yep.

Evan Brand: Uh— I would also say— I mean, we’ve got so many formulas. I would just say to look at our— look at our GI formulas. Justin’s got several custom formulas I do as well. You could check our sites, justinhealth.com, evanbrand.com. We’ve got many. And these herbs in isolation can work— can work pretty good, but we’ve really like to focus on the synergistic effective herbs together.

Dr. Justin Marchegiani: Yeah. like, for instance, Berberines, and Artemisia. If you look at Stephen Buhner’s book, he talks about the synergistic effect that you have with those herbs together. So, like one and one equals ten, not two. So, combining some of these herbs, they have to work phenomenal.

Evan Brand: Yeah, uh— you want to hit Tammy’s question?

Dr. Justin Marchegiani: Yeah. “I got stomach pain when I take Proteolytic enzymes. What does that mean? I had H. pylori and stomach ulcers twice in the past. So, number one, I’d make sure you’re not taking the enzymes on an empty stomach. I’ll take them in the middle of the meal. Okay? Number two, I would just see that, you know, if you didn’t take the enzymes, would you also have stomach pain? Or is it— Is the enzymes the only variable factor? And if you have a lot of stomach ulcers and those kind of things, number one, we need a support and start adding some healing and soothing herbs. Potentially, lower the dose and make the food more liquid or predigested in kind of like a crock pot type of format. So, the food is easier to process. Nothing raw. Even if it’s like, raw broccoli or like raw Paleo veggies, that may still be too much. So, I would look at crock pot liquid form, healing-soothing herbs and amino acids. Kind of what’s in my GI Restore. Uhm— add every variable in one at a time so that way you know. You get the foods dialed in, right? You get, you know, the type of food and the cooking process dialed in. You add some soothing herbs. You do the enzymes. You start with the very low dose. You work it up. You isolate. You do one of each variable, one at a time. So, you know what’s going on.

Evan Brand: Yep. And I would like to add. Make sure that you’re infection-free. You said you had H. pylori and stomach ulcers twice in the past. Uh— gastroenterology is very very very uh— inaccurate. Some of their testing. You can have false…

Dr. Justin Marchegiani: Yeah.

Evan Brand: …negative [crosstalk] in every week though. Just get retested. Make sure you’re free and clear. Make sure there’s no other infections or that H. pylori plus vitamins factors, which is something we test for. Make sure that that’s not there.

Dr. Justin Marchegiani: And again, here’s the deal, too. If you’re having issues potentially with food or enzymes, then you sure as heck gonna have issues with herbs to knock out the infection. So, work on the first three R’s first: removing the bad foods, replacing enzymes and acids to the right dosage, taken the right way, healing-soothing nutrients and adrenal support. So, adrenals, ginger tea, amino acids, healing-soothing herbs, and then, make the food really palatable so it’s easy to process.

Evan Brand: Uh— Great. Great advice. Angel, “Do you recommend diet to Diatomaceous Earth for Candida?

Dr. Justin Marchegiani: I think it’s great to help uhm— with the killing and binding effect that’s good at worms. Uh— I use it to kill ants in my backyard when I see them. Uh— Diatomaceous Earth has a high amount of Silica in it and it basically dehydrates the uhm— the exoskeleton of the— the insects. So, it’s a great non-toxic thing. You can also swallow it too so it can— it can dehydrate the worms, too, and kill them.

Evan Brand: That’s neat. Now, question from Narine, “You two are awesome.” Thank you, Narine. Where do you guys practice? So Justin, uh—

Dr. Justin Marchegiani: Everywhere, in the ether.

Evan Brand: Yeah, everywhere. Justin lives in Texas. I live in Kentucky. But, we are 100 percent via phone and Skype consults. That’s it. Uh— Riley, “ How long should you take the GI Restore 4 with probiotics after a parasite killing protocol?

Dr. Justin Marchegiani: Uh— typically, combination— typically, if we’re looking at it objectively ‘til calprotectin goes down, which is an inflammatory uh— protein that’s produced by the gut when there’s inflammation, and/or ‘til you’re infection-free. So, for infection-free, then we really want to see that calprotectin go down, and ideally, that correlates with symptoms and improving in the gut mucosa just becoming better and feeling better.

Evan Brand: I would say, generally, though, the given number— I tried to get people to run…

Dr. Justin Marchegiani: Two  to four months.

Evan Brand: …[inaudible] models.

Dr. Justin Marchegiani: Yep. I think two to four months on average. I know Riley’s case in particular. You know, he’s had issues with H. pylori in the past. So, there could be just some— some thinning gastric mucosa, that’s just more sensitive, and we just need to make sure that infections crossed off our list. And then start the timer, you know, two to four months from when that infection is gone.

Evan Brand: Okay.

Dr. Justin Marchegiani: Kind of thing—

Evan Brand: That’s good. That’s good. Uh— Addy asks, “ Do we  recommend Grapeseed extract for Candida?” Yes. We use it [crosstalk] in our formulas. It can help.

Dr. Justin Marchegiani: Absolutely.

Evan Brand: Uhm— uh— another question here. “Thoughts on prebiotics supplements?” I think it’s our last question uh— that we have time for. “Do we need prebiotics if we have lots of vegetables in the diet?”

Dr. Justin Marchegiani: I think you can throw in some resistant starch either some unripened banana flour or a little bit of a cool potato flour. I think that’s great. Throw in a protein shake. Uhm— we typi— and I think my Probio Flora, and maybe your probiotic, there’s a little bit of Inulin or Chicory root, which can be helpful. Uhm— but in general, some of that starchy carbohydrate, and it can start with the very small amount, can be helpful. And take a look at my videos on resistant starch for more info on that.

Evan Brand: Oh, good. Good. Good. Good. Glad you got a video there. Well, that’s all we got time for, question-wise. I think we hit most of them, though. Unless there were some off-topic. But, we hope this was helpful. Make sure you guys hit Subscribe if you’re not subscribed to the channel. Go ahead. Hit subscribe right now, because you’ll get notified. Make sure you hit the bell too, ‘cause we—

Dr. Justin Marchegiani: Hit the bell!

Evan Brand: …we’re back [inaudible]…

Dr. Justin Marchegiani: Everyone’s like, “Hey, Dr. J, like when are you gonna be live?” So, we’re gonna try to let you know a day ahead of time. But if you hit the bell, It’s gonna pop-up on your YouTube app, on your computer or phone. It’s gonna say, “Dr. J and Evan are live.” And then, you’re gonna know.

Evan Brand: Generally speaking though, you guys should expect us here every Monday at anywhere between 11:30 and 12:00 Eastern.

Dr. Justin Marchegiani: Yeah. That’s the general kind of gist and I’ll be online typically 9:30 to 10:00 CST, which is 10:30 to 11:00 EST on Fridays, for our FAQ for you all.

Evan Brand: So, s— you know, go ahead and stalk us here. Subscribe, hit the bell and we’ll be back for more content very soon. If you have…

Dr. Justin Marchegiani: Oh, one last question here.

Evan Brand: Yeah.

Dr. Justin Marchegiani: One last question. “Can you overdo with herbs?” Yeah, you can, Charlotte. So, just make sure if you’re— people thata are sensitive, they kind of already know it, right?

Evan Brand: Yeah.

Dr. Justin Marchegiani: They have issues with Vitamin C and issue with probiotics or issues with HCL, and it’s like— these are patients like we got to take our kid gloves and put them on ‘cause we got to go. Everything has to be very slow and very gentle. And it’s not that you’re— you’re weak or have— you know— It’s not anything— It’s not a negative on you. It’s just your system, where it’s at. So, if we go a little bit slower, it helps. It’s kind of like, you want to take a cold shower, get in the shower. Get it on warm and then just inch the dial a little bit co— you know, to the cold direction. And then, before you know it, in three to five minutes, you’re in a cold shower. And it wasn’t that difficult. So, if we have to, we can go slow. Of course, working on ginger tea and soothing nutrients to get the gut lining more tonifying, relaxing things, adrenal support. And then we can inch into the herbs as well. So, for sure. Absolutely.

Evan Brand: Oh, I’m gonna advise, two cents…

Dr. Justin Marchegiani: Yes.

Evan Brand: …because you made some word adrenal. Yeah. If your adrenals are weak, you gut protocol is going to be much more uh— heavy hitting on you. So, if— if you’re working on with a practitioner and you guys are just looking at the gut, make sure you’re asking questions about thyroid and adrenals and hormones. Because, you know, Justin and I are utilizing a Three Body System Approach, which is adrenals, gut, thyroid detoxification. Things like that.And if all these other pillars aren’t there, and you’re just hitting one avenue really hard, you’re gonna crash out. So, make sure those other— other pillars are involved. Otherwise, the progress will not be as well. And I could explain why you’re not handling the herbs as much.

Dr. Justin Marchegiani: And it’s human nature. Once people find out they have a critter in them, they’re like, “Get rid of it! Oh, my gosh! This is awful.” And I— I get it. So, normal reaction, but we have to make sure the bigger picture is we don’t to get reinfected. The bigger picture is we don’t want to feel worse either. So, there’s this a sequence in which we have to do. And it takes a little bit of trust because the normal reaction is, “Get rid of it now.” “Get rid of it yesterday,” right?

Evan Brand: Yeah. For sure.

Dr. Justin Marchegiani: Okay. Awesome. Well, great call. Slam that bell. Give us a share. We appreciate everyone watching. And hope everyone’s health takes one notch in the right direction today. [crosstalk] Appreciate it all.

Evan Brand: Take care.

Dr. Justin Marchegiani: Bye, Evan.

Evan Brand: Bye.


References:

Wise Woman Herbals herbal douche products at http://www.wisewomanherbals.com/

TRUCOLLAGEN https://justinhealth.com/products/trucollagen/

Probio FLora at https://justinhealth.com/products/probio-flora/

Just in Health at www.justinhealth.com

www.evanbrand.com


The entire contents of this website are based upon the opinions of Dr. Justin Marchegiani unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Justin and his community. Dr. Justin encourages you to make your own health care decisions based upon your research and in partnership with a qualified healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Dr. Marchegiani’s products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products.