Functional Medicine Approach for Urinary Tract Infections (UTI) | Podcast #356

One of the most common human infections is one that people rarely speak about. Urinary tract infections (UTI), also known as bladder infections, impact 10-20% of women at least once a year, and the specific treatment intervention is prescription antibiotics. Middle-aged women with chronic conditions like autoimmunity, dysbiosis, and hormone dysfunction are regular patients in functional medicine, so regular taking of antibiotics could pose a problem.

Dr. J and Evan talk about that when optimizing microbiome health, hormone production, and immune tolerance, it is crucial that bacteria are allowed to thrive, and antibiotic use poses a warning to that opportunity. With that said, if urinary tract infections (UTI) are among the most common conditions physicians see, and we are attempting to avoid circumvent antibiotic use, what functional medicine approaches do we have?

Dr. Justin Marchegiani

Dr. Justin Marchegiani

In this episode, we cover:

0:00 – Introduction
6:31 – N-Acetylcysteine in protecting the urinary bladder
11:17 – Foundational strategies in keeping the urinary tract healthy
17:10 – Antibiosis versus the association of N-Acetylcysteine, D-mannose, and Morinda Citrifolia fruit against UTI
19:11 – Men’s role in preventing UTI

Dr. Justin Marchegiani: Dr. Justin Marchegiani here with Evan brand. And today we are excited to talk about functional medicine approaches to address UTI or urinary tract infections. My immune system is just a little bit under the weather, so I’ll be channeling my inner Barry White today. Really excited for that. Evan, how you doing man? 

Evan Brand: Hey, pretty good. Yeah. I hope you feel better and get back to kicking butt, which you’re still kicking butt but most people would call it in but I’m glad your brain is working enough and we’re gonna get this thing done. So, 

Dr. Justin Marchegiani: I haven’t had a sick day over a decade. I don’t, I don’t plan to have a sick day ever.  

Evan Brand: Good. Good. Good. Alright. So, now, uh, with UTI, I mean this is something that’s extremely common. We see it a lot in young children because their poop gets in to their urinary tract whether they’re wiping the wrong way or whether this is a young child that’s still using diapers, so I’ve seen it with our children, we’ve worked on our kids. I’ve seen it with a lot with the kids I worked with clinically. And then adults we see this a lot, where a lot of it is due to sexual transmission. I mean we’ve seen many cases where if we support the female, the male is the vector and the woman start to get almost resentful towards their husband because they know every time, they have sex they’re gonna end up with UTI. So then, that really affects their sexual health and their relationship. And so, today’s podcast hopefully will encourage people to take this seriously and we’ll have some strategies you can implement to get both you and your spouse if that’s what’s happening and better shaped where this is a non-issue. 

Dr. Justin Marchegiani: Do we have any data on the semen quality, the semen quality affecting, uh, urinary tract infection of females?

Evan Brand: I’m gonna look it up but I know clinically and I know you’ve seen the same thing that we hear that story all the time of where everything is fine and then boom they have sex and then all of a sudden it’s they have a UTI. 

Dr. Justin Marchegiani: Yeah. I know in, um, in men 

Evan Brand: So, here’s the study right here, semen culture and the assessment of genitourinary tract infections in the male. It says here is, uh, contributes approximately 50% of the cases.

Dr. Justin Marchegiani: Yeah. I wouldn’t be surprised if nutrient deficiency has a lot to do with it because I know zinc is very high in semen, right? Um, very important for the health of the sperm and I know zinc also has anti-bacterial, anti-viral qualities to it. So, I wouldn’t be surprised if someone’s more nutritionally deficient they’re gonna have less zinc in the semen and that less zinc will make it harder, make it easier for bacteria and other critters to grow. So, just a thought, again, you know, we try to, you know, high level thinking, you know what’s the mechanism, look at all the downstream signals that could be one component though. 

Evan Brand: Yeah. It’s talking about these different types of bacteria in this male study talking about how it plays a role in genital tract infections and some of these are natural inhabitants of the male urethra which can contaminate semen during ejaculation. So, there’s your answer.  

Dr. Justin Marchegiani: So, it’s almost like men could have a subclinical kind of UTI. 

Evan Brand: Exactly. 

Dr. Justin Marchegiani: That could be affecting it. So, if you’re a female having chronic UTI issues, you have to have your partner looked at or addressed. And we’ll talked abour natural strategies of course keeping sugar down is going to be one of the big ones because one of the biggest bacteria involved in UTI is gonna be E. coli. E. coli you’ll see high in bacterial imbalances in the gut, you can also see some, I think some Pseudomonas in some as well as some Klebsiella but it’s mostly gonna be E. coli.

Evan Brand: They were talking about E. coli and even Mycoplasma in that study, which kind of interesting. 

Dr. Justin Marchegiani: Yeah. Exactly. I know, um, yep, that’s a big one for sure. 

Evan Brand: Some part, you know, some families or couples, they’ll end up just going to using condoms because obviously that’s gonna work and that’s gonna prevent the critical transfer but really the better thing is to get the health of your spouse improved and so, if you’re a female who’s done some of the conventional strategies, let’s kind of go into that now. Some of the conventional stuff that’s being done and we’ll compare it to the functional strategies but if you’ve done some of this stuff and you’re still struggling that’s when it’s time to get your spouse on board. And I know, you and I, we really like to work with couples and we like to get the whole family healthier together because we find that if we just focus on the female that her results are not as good and you know, this actually kind of carries over into H. pylori and all the work, you and I do with gut infections because we see cases where a female will use herbs successfully to eradicate certain infections in the gut. She’ll then get reinfected from the spouse even not into sharing cup, spoons, drinks, kissing and then they’ll get infected. So, as much as I can, I’m trying to bring the husband on board into these health protocols. 

Dr. Justin Marchegiani: Yeah. So, a couple of things out off the gates that men can do to help support the women is cut the sugar out of their diet or at least drop it down to the point where you’re not growing some of the microbes in the urinary tract. That’s helpful. You can also add some things in. Like ginger is actually very helpful so maybe some ginger kombucha can be good or some really strong ginger tea is wonderful. You can also add a little bit of Manuka honey because there’s a lot of data on Manuka actually decreasing E. coli and Staph in the urinary tract. So, these are some simple kinds of easy things. You can even take some raw cranberry juice. Raw cranberry juice is very high in D-mannose, which is a large sugar molecule. The body does not digest but it creates like, uh, magnet-like effect. It’s like dragging a magnet across a surface and grabbing iron filings and pulling them out. Think of the iron filings is the E. coli and so it kind of pulls them out. So, those are some easy simple strategies for some men out of the gates is ginger, cranberry. I would say just make sure you’re hydrated enough, right solution to pollution is dilution, Manuka, and keeping the sugar down. Those are excellent strategies out of the gates. 

Evan Brand: Yeah. And NAC, so we wanted to talked about NAC because NAC has been pulled from Amazon and this nutrient is getting harder to access as just a regular consumer. Fortunately, we work with professional companies, so we still have access, we still do manufacture NAC-Glutathione combos but there was a paper that we have here on NAC and the cool thing is I know you’re taking NAC right now.  

Dr. Justin Marchegiani: Yep. I’m taking up to four grams a day to help biofilms if in the sinuses, it also, um helps with decreasing virus replication in case I have any viral stuff going on. I think I have personally just a little, uh, rhinovirus. That’s what I personally think and then outside of that, um, increasing glutathione, antioxidant support, biofilms, helps with mucus, so it keeps the mucus kind of flowing from. So, it’s, so it doesn’t, um, impair oxygenation and blood flow. 

Evan Brand: See, if you can pull up or highlight that paper, I just shared on the screen there. You know, for folks listening you’re just missing out on this part of it, but that’s okay, we’re just trying to just show you at least maybe a couple of studies a week. That kind of 

Dr. Justin Marchegiani: Yeah. If you’re listening, yeah and if you’re listening here, we’ll put the video link below, so don’t worry about it, just come and check about it later and we’ll put the link down below. 

Evan Brand: All right. So, this is titled, N-Acetylcysteine Protects Cells from Bacterial Invasion, I like how they call it an invasion, and Displays Anti-Biofilm Activity against Urinary Tract Bacterial Pathogens. So, long story short, they discuss using antibiotics, which were really, we can dive into that. But really that is the conventional approach with this stuff, and the problem with antibiotic resistance problems and so you’ll have women that’ll do these formulas whether it’s in this study they’re talking about cipro which is dangerous stuff. I don’t like the sound of cipro at all, for many of the potential permanent tendon issues and other side effects associated with it. 

Dr. Justin Marchegiani: Yeah. Cipro’s in the fluoroquinolone family which can negatively impact mitochondria and connective tissue so if you’re gonna use antibiotic, try to use one, not in the fluoroquinolone family. Maybe amoxicillin, a tetracycline, just talk to your MD if you’re gonna go that route, to avoid that antibiotic at least. 

Evan Brand: Yeah. But here’s the conclusion, NAC is a non-toxic, antibiofilm agent and can prevent cell invasion and formation by uropathogens. So, once again, NAC for the win. This stuff is incredible. 

Dr. Justin Marchegiani: Yep. And again, with antibiotic is like I’m always about, let’s do the more natural things first and kind of go, least invasive to more invasive, right? And antibiotics to be the top part of the more invasive side. 

Evan Brand: This is interesting, I guess this was an Australian researcher, doctor who put this study together. They’re saying here that in Australia, you know, there’s an estimated 150 million infections and this is 12% of hospitalizations. 

Dr. Justin Marchegiani: UTIs are?

Evan Brand: For UTIs

Dr. Justin Marchegiani: Wow. Holy smokes. 

Evan Brand: And 30% of all women have a recurrent episode of UTI and then of course the problem with the UTI, right, UTI kind of sounds like, oh it’s not too bad. But I mean this stuff gets up and infects your bladder that gets really bad and then it can even farther ascend and then infect your kidneys and then that’s when you get into a really big trouble and that’s where they talk about sepsis and some of these other literally and potentially fatal infections from UTI. So, when UTI is kind of one of those, it sounds like, it’s just like this easy, not a big deal, but it can turn into a big deal. 

Dr. Justin Marchegiani: Yeah. So, just kind of like out of the gates, like what are the symptoms of UTIs, right obviously, like pain, pain during urination, you can see a lot of cloudiness in the urine, right? Potentially, even blood in the urine. It can have a really strong smell as well. It can even create pelvic pain in that area that pelvic or pubic area for sure. It can also move up so women have a very short urethra unlike men, that urinary tract can go to the bladder very very easy just because the distance is really short, so once it goes to the bladder, right, you’ll see pelvic pressure, you may see blood in the urine, frequent painful urination, lower abdominal discomfort and then it can continue going up from there into the kidneys. That’s where’s you’ll start noticing a lot of back pain, flank pain, um, you may notice starting to get chills and fever and maybe nausea and vomiting. And usually, once it starts to get into bladder into the kidneys, you know, you may want to look at seeing conventional medicine for the antibiotic at that point, definitely in the kidney. But, I mean, I think if people can be educated about this and be on top of it, I think you can avoid a lot of that upstage, um, conventional need for medications.

Evan Brand:  Well, like many other things that we’ve talked about. Early treatment is key. So, if you can come in and hit some of this stuff hard with D-mannose, your N-acetylcysteine, we use these cranberry extracts very effectively. You and I have also used some professional formulas that contain hibiscus and parsley and horsetail. So, the goal really, I think is to try to break down into like three main categories. So, you go the biofilms, breaking components like your NAC for example or you could add in like natto, Cerezyme or some sort of other proteolytic systemic type enzymes maybe even lumbrokinase would help. So, that’s your number one is your biofilm busting. Number two, you’ve got your antimicrobials that you and I use like bearberry, barberry maybe even clove or oregano might be helpful. Silver, I think, is worth to mention. And then, I would say the third mechanism of action is the anti-adhesive properties so you’re really trying to help flush things out. So, that’s where just hydration comes in. 

Dr. Justin Marchegiani: Yeah. Mannose. 

Evan Brand: And some of these herbs, 

Dr. Justin Marchegiani: Mannose too. 

Evan Brand: Yeah.  

Dr. Justin Marchegiani: Because that’s gonna pull, that’s gonna help pull the E. coli off like iron filings, right, like I gave that under the gates. So, just couple of foundational things. We’re kinda, we’re kind of hitting some of the meat here, I want to just kind of make sure we set a good foundation. So, out of the gates, women are gonna be more prone because of a couple of reasons. Okay. Number one, we talked about the intercourse and the injection of semen that may either have bugs in it or it may just essentially expose a weaker urinary tract so of course the first thing is hydration if you’re a female and getting up after the sex, getting vertical and going to the bathroom. Get that urinary tract moving, get’s some hydration in you. That’s a really good first strategy our of the gates and of course if you’re prone to having UTIs, you may wanna have a powder of D-mannose like we mentioned or some of the formulas that Evan mentioned, some D-mannose, Uva Ursi, um, parsley is excellent maybe a little bit of silver but you can just start a little bit of D-mannose, a little bit of cranberry extract and a little water and drink that before bed or you know, after a, um, interaction like that. The next thing is, if you can look at the hormones, right, hormones can play a big role so you have the high, you have the low. So, women that have very high levels of estrogen especially women that are on birth control pills that’s gonna shift the urinary tract pH based on the high levels of hormones, that can make it easier for the E. coli to grow because E. coli does not like an acidic environment. And when you started to make the environment more alkaline, right, you usually hear alkalize or die well not necessarily. The urinary tract if it’s alkaline can actually grow bugs, so birth control pills can actually cause the bug to grow to the alkalinity.  You can also see the opposite, right, the goldilocks effect. When women go into menopause and their hormones drop, low hormones can also have an impact on the immune system in the urinary tract and that can cause, it can be more, you can be more prone to have UTIs if you’re menopausal with low progesterone, low estrogen because that plays a role in the environment and the immune system and the IgA levels in the urinary tract and so not too hot, not too cold, right? Not too much hormones, not too low hormones, so birth control pill on one side too much, menopausal issues, low hormones on the other side. You really need to work with a good functional medicine person to get the hormones dialed in it, may not be a simple, hey take to something that you may have to fix the hormones too. 

Evan Brand: Yeah. Good call, good point, bringing that up. And that’s more of like a longer-term thing. That’s like if you’re trying to get well and stay well, that’s stuff we’re gonna be looking at. So, is it possible to come in and use some calcium D-glucarate or something like that to help that pathway and get rid of the excess estrogen? I think it could help but is it going to like acutely get you out of the UTI maybe not so I think it’s good you’re mentioning to have a plan meaning like a long-term health functional medicine health plan that then prevents you from having to do some of these acute strategies we’re talking about.  

Dr. Justin Marchegiani: Yeah, I mean there’s a palliative kind of, um, non-root cause support that we have but we try to always package in the palliative stuff with lifestyle changes that make it more holistic and make it more root-cause and then we also dive into the hormonal aspect and also, I would even say gut aspect. I’ve seen imbalances in the gut bacteria, shift and influences the urinary tract microbial balance too. So microbial imbalance in the gut has a way of shifting microbial imbalance in the urinary tract and it could be just 80% of the immune systems in the gut and that’s having a major effect. It could just be some of this stuff’s working its way down there through moving the intestinal tract. It has a way of shifting or migrating or moving in some way, you know, those kinds of things. But either way look at the gut, that’s where a lot of the immune system is. Look at the hormones, look at medications that could be influencing these things. Look at hydration, those kinds of the root, I think starting situations, you really wanna have your head wrapped around. 

Evan Brand: Yeah. In regards to testing you can do this at home. They have companies that make at home UTI test strips that you can do, where you just urinate on the strip and you’re gonna be able to test your leukocytes and they have a little reference range that you can look at and basically the dark on most of these it’s purple, the darker the purple, the more severe the infection is. And we had incredible results with our daughter using some of the D-mannose, we some chewable versions, we did some of these herbs mixed in some apple sauce and we retested using these little pee strips and I want to say, I’d have to ask my wife to confirm, it was either two or three days, we completely got it from a deep dark purple indicating a very intense UTI to nothing. It was completely white. So, the brain is called azo, A-Z-O. And they also make other things, I think they make like ovulation strips and that kind of stuff for more like female health. But this urinary test strip, you’re looking at maybe ten bucks for a pack of these. So, if you do have suspicion or if you’ve had chronic UTIs, this is something that I would recommend you at home because so many times you and I hear a story of a woman having to schedule an appointment, get into the doctor. Yep, I have a UTI. It’s like you could have done that and figured it out at home in two minutes for 10 bucks. The accuracy is very very good. 

Dr. Justin Marchegiani: Absolutely. 100% And of course, um, there’s some tests if you do like a uroscopic or a microscopic urinalysis, you know, we’ll be looking at leukocytes, we’ll be looking at protein in the urine. We’ll be looking at pH, we’ll be looking at potentially bacteria. E. coli, looking at the actual microbes in the urine, that’s helpful and then obviously just from a diet, just for me a lifestyle strategy. This is obviously going to pertain more to kids, right? Just teaching your kids how to wipe the right way, right? Females, front to back, kind of common sense, but kids obviously develop blood habits and that could be a simple, easy lifestyle methodology. They can, they can fix that problem and just getting more water, more hydration, if, um, kids have a compromised immune system due to the too much sweets, um, obviously artificial sweeteners like aspartame, Splenda, those can impact the microbes as well. Those things can compromise the immune system and shift the micro, the micro, um, kind of balance, microbiota balance in the gut and in the urinary tract. 

Evan Brand: Yeah. Let me show this one more thing. Do you mind bringing this, highlighting this paper? 

Dr. Justin Marchegiani: Yeah. Absolutely. 

Evan Brand: There’s one more that we wanted to show people, this was just titled, Prospective study to compare they said antibiosis, they’re talking about antibiotics versus NAC, D-mannose and Morinda fruit and the conclusion of the study at the bottom here, D-mannose and NAC resulted in similar to antibiotic therapy. So, even if somebody wants to nitpick and argue, well antibiotics are like

Dr. Justin Marchegiani: Better. 

Evan Brand: They’re not. They’re not. Now, I’m not saying that in a severe situation where your kidneys are affected and you’re going septic, I’m not saying, I’m going to try to do this, but I’d be doing all of it, I’d be doing the mannose, the NAC maybe the antibiotic if I had to, but I mean, based on the stuff you and I’ve seen clinically based on more than what we’ve looked at in these papers alone. I mean, the cool thing about PubMed too, is you’ll be able to have related articles pull up like you could go into this one. D-mannose and Hibiscus and Lactobacillus probiotics. You know.  

Dr. Justin Marchegiani: Yeah. Probiotics are gonna have a major influence as well due to the acidification of that area. I mean, you can depend, depending on where you’re at, you could potentially even do intervaginal probiotic, you know, you could put the capsule in let it dissolves or you can mix it in, uh, with little, a little bit of aloe or shea butter or coconut oil, something that’s gonna dissolve and um, you could essentially mix it in, you know freeze the cube or refrigerate the cube so it’s solid and then insert intravaginally and that will kind of dissolve and then it will contain some of those nutrients to help support the vaginal canal and depending on where you’re at for some yeast you could even do that same thing with boric acid too. I recommend some kind of a carrier though, just so, it’s uh, just so, it’s not as abrasive if that canal or that tissue is really sore or irritated it just provides some moisture to that area as well and won’t irritate it. And if you’re unsure test the, test the moisturizer whether it’s aloe or shea butter or coconut oil, test it before you put any of the extra stuff in it, so you know, if that’s a problem at all.    

Evan Brand: You know, what I’ve also seen to be beneficial, I’ve seen some homeopathic vaginal suppositories for UTIs. I don’t know much about them, but I’ve had women try them and they have worked, when everything else failed, so I think you should be open to it. And the probiotics are game changer too, as you mentioned, you could do intravaginal with the capsule it’ll just dissolve or just oral probiotics has been helpful so as you mentioned the gut, you know, that’s something we’re gonna look at. So, if we see a female who suffer with UTIs and we see she’s got a lot of issues on her stool test, you know, we can’t say directly, hey this is why you have UTIs. But if we fix the stuff in the gut, chances are high that they’re gonna suffer less and less frequently from UTIs. It’s really, really important as you mentioned you got this vaginal microbiome, you’ve got the oral, you’ve got the gut, you’ve got the skin microbiome, so, I mean if anywhere there’s dysfunction or dysbiosis going on, I think they can affect the whole system. 

Dr. Justin Marchegiani: Absolutely. And then, men play a part of the role, you know, in this whole thing. So, get your sugar consumption down, better hydration, could always throw in a little bit of ginger or cranberry kombucha that’s a really easy simple thing. Just to add in as a routine. Sometimes, it’s easier to add things to a routine than pull things out. 

Evan Brand: Well, think about how many men, you and I have seen and work with over the years with gut issues so, I mean getting their gut straightened out too is gonna be my goal because I’m sure that’s gonna affect what’s we’re seeing in these paper zone like semen quality, and they’re not passing these microbes, you know, via sperm. So, man, you gotta get on board. Women just I, you know, I feel bad for them because they take a lot of the blame, they take it upon themselves like there’s something wrong with them and in many cases, there definitely are issues with the dysbiosis and the female but in the men they kinda get off the hook so, we’re calling all the men out here, you gotta get involved too, you gotta get your health involved. If you’re over there, eating pizza while your wife is sitting here cooking a paleo meal, you gotta get on board because, you know, this is a team sport here. 

Dr. Justin Marchegiani: Yeah. And you can always use a barrier method if not, right, that’s an easy way at least in the interim and then also just getting the hydration up and avoiding the sugar can make just a huge difference. Sometimes, it’s not even 100%, just an 80 20 can make a huge difference on that. 

Evan Brand: I know how men are, being a man, so if the wife says, uh, honey you’re gonna have to use condoms for the rest of our, uh, sex life, I think that’ll be a, easy quick motivator to get them on board and they’re natural. 

Dr. Justin Marchegiani: Totally. Yeah. I find like kind of in the men sphere, there’s like two kinds of men. There’s like the men that are like biohackers that are like always into like optimal performance trying to improve and get everything kind of optimized in their health and their life and their come some guys that they kind of just, they’re  a little bit more slow to the punch and they’re motivated by what the rest of their family is doing, their wife’s doing, and then their wives kind of get them on board, there’s like kind of two classes like that, I think me and you tend to be more in the biohacker class and we see a lot of biohackers that are in, right, you know, that are really motivated and they’re all about performance, performance and then some their wives are more on that side of the fence and the wives kind of get them motivated but most of the time though, once someone can see their life improve and usually if you get healthier, you don’t just improve in the urinary tract, you improve in cognitive, mood, libido, energy, digestion, so women, if you can get your husbands on board, they’re gonna see a lot of buy and hopefully other areas and hopefully you’ll be able to get them a long-lasting buy in which is really important for energy and just, you know, people being, um healthier which is important. 

Evan Brand: Yeah. Well said. We can mention this comment here that came in the live chat and then we can wrap it up. We’ve kind of hinted at this but we didn’t say it directly, when we talked about UTIs, I mean a lot of times, we are referring to the bacteria but in many cases there’s a yeast component too, so there’s a fungal component, here’s the cool thing though, you and I are always using blends and these blends are not only antimicrobials but also anti-fungal, anti-yeast. So, someone in the comments here wrote that they kept getting UTIs even after getting treated until they started yeast treatment and that’s a cool thing. Think about if you come in with antibiotics, so let’s just quickly compare the conventional and functional approach. You come in and do the antibiotics, those are not anti-fungals, but if we’re using something like bearberry, barberry, berberine, cloves, silver, Saccharomyces boulardii probiotics, we’re creating an antifungal, anti-microbial, anti-parasitic protocol all in one, which is awesome because sometimes we’re killing multiple birds with the same stones and that’s why we love what we do. 

Dr. Justin Marchegiani: 100% and of course, you know, a good history will kind of figure this out, based on you know, if you have a new sexual partner or not, STDs always can be a thing, so we’re looking at Chlamydia, maybe Gonorrhea, right? And so, these types of infections, I think we could probably see some improvement with some of the natural things especially if we add in silver and such but these types of things, if you’re not having results, they may require a special kind of antibiotic, if that’s at play. And so, obviously, you know, it’s gonna be history dependent, if you’re in the steady relationship then that may not be a thing or if you’re not sexually active that probably isn’t gonna be a thing but it’s always good to kinda keep that in the back of your differential list of things that you kind of work up through from least likely to most likely. 

Evan Brand: Yeah. Good call. So, on that NAC paper, it actually did talk about Chlamydia and it talked about the mycoplasma and there was a couple others in there and it was talking about the anti-adhesive, anti-biofilm properties of the NAC. So, even if it were STD, I think NAC is something you’d still wanna implement. 

Dr. Justin Marchegiani: Yeah, I mean, usually you’ll gonna see some level of discharge too with some of the STD stuff but worst case, you know, you can just tested try some of the simple things out of the gates. A lot of times the history will tell you, especially if you know, if you’re, um, had intercourse in the next day, you know with your husband or partner and the next day you’re starting to feel some issues, then it’s probably gonna be on the E. coli side of the fence which is 90% of the time, so you know, if you have 90% odds with something, we’re gonna go with that out of the gates for sure.  

Evan Brand: Yeah. Okay. So, testing strategies just to summarize, you could do the at-home test strips for this, we think a good stool test would be, in order to figure out what’s going on with you’re gut and how’s that affecting your microbes down south same with your partner, if we can get them on board, get your stool looked at, a urine test is helpful too because we’re gonna be able to look to Candida overgrowth and other types of fungal colonization. So, we like the organic acid, so an oat, a stool and some of the at home test strips, I think that would be a great starting place because you could do other things, blood work, and as you mentioned like the urinalysis and like in the conventional lab, you could do that too. But you might not, if you do these top three. 

Dr. Justin Marchegiani: Absolutely, and then the big symptoms that would differentiate an STD over UTI are gonna be like more systemic symptoms, so like nausea, fever, swollen joints, sore throat, symptoms that are kind of gone more systemic and of course there can be some localized symptoms that can be more severe like extreme discharge, severe rash in that area, blisters in the genital area, but look for more systemic type of symptoms that could be driving that. 

Evan Brand: Okay. You’re saying more systemic symptoms would be what? 

Dr. Justin Marchegiani: The ones I just mentioned, so pelvic

Evan Brand: No, would be a UTI?

Dr. Justin Marchegiani: No, that’s gonna be more of an STD, so think of STDs are more severe therefore the symptoms are more severe. They’re more systemic. So think of systemic symptoms are things that are more severe, localized symptoms, right, that means the microbes haven’t spread as much and they’re less severe, so more severe think of the STDs. 

Evan Brand: Got it. And then you mentioned in the beginning if the UTI is more severe that’s were the back gets involved in the case of the kidneys, you know, there are people that, they perish due to UTIs if they go septic so obviously, you would have a lot more issues than you would know by then. You’d be in real bad pain.

Dr. Justin Marchegiani: Absolutely. Yep. 100%. And again, like you know, UTI, on a desk, can go to the bladder and then the kidneys and then, you could have a fever, you could have these things, so as a UTI gets more severe that could definitely drive the symptoms up as well. But usually, what people can see it because it’s just following that urinary tract, it’s going from the urinary tract to the bladder, to the ureters and then up to the kidneys. So yeah, usually you can see that and feel it, the pain starts to move up. Well, anything else, you wanna add? 

Evan Brand: No. I’m just gonna say, we work with this issue all the time. We’re really happy to help people and to provide solutions to what have been a major issue. A pain, an issue and like I said with people’s sex life and with just people’s personal health. I mean this is something that’s a big burden for a lot of people especially women. So, we’re really happy and fortunate to have outside of the box tools that we use with great success and we don’t only back it up with clinical experience, we backed it up with some of the research we’ve dove into and the professional formulas we use are tried and true. So, if you need help, please reach out, we’d love to help if you wanna reach out to Dr. J you can at justinhealth. If you wanna reach out me Evan Brand, you can do so at and we both work worldwide via facetime, phones, skype and we send products to your door, so if you need to get any of these labs done, investigate you, it doesn’t matter if you’re in California or Oregon or Michigan or Florida or New Mexico or Australia or Canada or Europe, we can do it, we can help and we work with people around the world, we have for decades so it’s just a true, true pleasure to get the hands-on experience with this issue because I think the most empowering thing is to know that you’re not a victim meaning you’re not just going to have to go on antibiotics. That’s just the foghorn of the conventional approach, and it’s just so empowering and inspiring to know, there’s other ways, other tools, there’s other approaches that are very, very successful. 

Dr. Justin Marchegiani: 100% Yeah and if you guys enjoyed it, There’ll be links right there to work with us. Hit that thumbs up, helps the search algorithm improve so more people can see our information and give us a share, give us a comment, write us a review, we’ll put links below to do that. Thanks, y’all, you guys have a great day, we’ll talk soon.   

Evan Brand: Take care. 

Dr. Justin Marchegiani: Bye Evan. 

Evan Brand: Bye. Bye.


Audio Podcast:



The Essential Oil Hormone Solution | Podcast #220

There are a lot of great practitioners out there who will help navigate that journey for you, but you’re making the best decisions and there is ownership of you. You are the “CEO” of your health.

In today’s podcast, be amazed as Dr. J interviews his lovely guest, Dr. Mariza Snyder, a functional practitioner and a renowned author of 7 books, the most recent being about one of her absolute favorite subjects – essential oils! Listen and learn about the importance of self-awareness, self-care, and other important recommendations for one to start implementing. Stay tuned for more and don’t forget to share!

Dr. Mariza Snyder

Dr. Mariza Snyder

In this episode, we cover:

04:53    The Luteal Phase

07:14    Estrogen-Dominance

10:29    Adrenals

13:26    Self-Healing Awareness

14:41    Plant-Based Medicine

18:13    Nutritional Compounds

24:11    Gut

25:49    Essential Oil-Wise to Support Luteal Phase

27:27    Perfume Alternatives


Dr. Justin Marchegiani: Hey there, it’s Dr. Justin Marchegiani. Welcome back to the podcast. We have Dr. Mariza Snyder on the show today. Dr. Snyder is a hormone expert and essential oil expert which is great because essential oils can be really helpful and they can really help with the stress response. So we’re gonna dive in to the hormones, we’re gonna dive in to some things that you can do right now to help kinda push your hormones back in the balance. Dr. Mariza, welcome to the podcast, how you doin’?

Dr. Mariza Snyder: Thank you so much for having me. I am great. So happy to be here.

Dr. Justin Marchegiani: Excellent. Very cool. So, I’m just curious, I was talking to you kinda pre to show. When I was uh, in doctorate school, you are actually right on the way out just a co- couple of quarters before me, so I actually remember you, we were kinda reminisce in a bit. And I wanted to- to- kinda, how did you make your exit on the doctorate chiropractic side into the functional medicine hormone side? What was that journey like for you?

Dr. Mariza Snyder: Absolutely. Well, there even reason why I pivoted the way that I did. So, 4, 15 years when I was little girl, 7 years old, I uhm- I basically had some pretty crazy head traumas, neck traumas, and that led to chronic migraine pain. And I was told, I can’t tell you how many times I was told I was gonna live with this pain, and I believed it for so long.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Well, fast forward, I, you know, growing up, I struggled, I missed- I missed slumber parties, I miss school, I missed all the fun things. I remembered as a kid, just thinking, “Man, I missed out so much on life” because I was in pain all the time like, these migraines would light me up for days on end. Just in a dark room with a cold cloth over my head, just praying to go to sleep. So, 24, I- I am a biochemist at elaborate floors of more national laboratory.

Dr. Justin Marchegiani: Oh, wow, yeah.

Dr. Mariza Snyder: And uhm- there was uh- a- a woman there who was- who- was like, “listen, we…”, uh “…I have a doctor who could probably get you out. And uhm, they get you from your- get well from your migraine”. I’ll be honest with you, at that point, it been 15 years, and I did not believe any of it. I was like, “I don’t know. This is I’m- this is my lot in life, missed thing, I’m- I’m stuck with this. I got my drive this- I’m gonna beat this sucker every single day or every other day. I’m good”. You know, “I’m gonna go and become medical doctor, I’m gonna go prescribe meds, just like I’m taking right now” [chuckles].

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: It- it’s just- it made no sense whatsoever, but when you don’t know that there’s a different paradigm, you just kinda follow along in suit. Uhm, because the practitioner was uhm- on the way home, I went and so- sought out care, and it was interesting, it was more of a functional practice of- that uh- and I didn’t realized what a functional practice was. I didn’t even know anything like this existed. I did have chiropractic growi- growing up and, I- unfortunately they weren’t able to clear out those migraines, but this practice had. Acupuncture, upper cervical, nutrition-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -the whole gamut of things, and after 90 days, after care, I was migraine free, and it blow my mind. So, that opened up the idea of- of this idea of healing that I’d never even thought of before. Literally switched past like that [snaps finger].This is over a summer. I was heading out to- to medical school, switched past over to-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -chiropractic school, this was the thing. Uhm, and, throughout that process, I was still educating and learning and thinking myself like how- how does the body have the ability to heal. And nutrition became a really big part of my life. So once I got into practice, most of women I was treating uhm- we’re dealing with hormone issues, I was also dealing with hormone issues, ’cause- ’cause why not have another health issue at the-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: after- after this other one.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: And I realized that although, uhm, chiropractic could be supportive to some of the things that it was really nutrition and lifestyle and really getting the core root of what was going on with them that was gonna move the needle. So, that became a big part of the practice.

Dr. Justin Marchegiani: That’s cool. I remember- if I remember correctly, you were an upper cervical chiro expert, right?

Dr. Mariza Snyder: I was because of the migraines. Yeah?

Dr. Justin Marchegiani: Yeah. And then I’m just curious, how far, like, if we just kinda quantify as a percentage, how far did the upper cervical get you versus the other half where you were incorporating more natural and- and nutritional and supplemental techniques?

Dr. Mariza Snyder: Absolutely. Well- if, you know, it was definitely case by case. Some people like myself-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -had [crosstalk]. And uhm- and it was uh-

Dr. Justin Marchegiani: [Clears throat]

Dr. Mariza Snyder: -things were wrong. There was  misalignments, there were problems, up at c122. So, but then there were other instances where a lot of of women that I was treating had migraine pain because of the-

Dr. Justin Marchegiani: Hormones?

Dr. Mariza Snyder: Yes. Hormones. Luteal phase-

Dr. Justin Marchegiani: Inflammation…

Dr. Mariza Snyder: -just drop of progesterone-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -and estrogen, and that was more of a lifestyle, nutritional, supplementation aspects. So, I would say the pain on a person, it they was hormone-driven, uhm, maybe 25%, uh 20% chiropractic, but really, I wasn’t making the changes until we stepped in to the nutrition and supplements and lifestyle.

Dr. Justin Marchegiani: Okay, got it. So, you’re kind of- it- the more on the physical stressor sides, the chiropractic so to help more of the alignment and- and the- the nervous system communication on the hormone side, we gotta make changes above and beyond. That totally makes sense. Now, you kinda went to an area that I love. You talked about the luteal phase. Can we just kinda- walk the average listener through what a typical cycle looks like. Follicular, lutial, and- and can you describe that physiology 101 for the listeners?

Dr. Mariza Snyder: Sure thing. So, if you’re still having a menstrual cycle, right? Which happens between like, I don’t know, ages 11 to 13 or so, all the way until where, well, until menopause. And menopause is defined as the disease of a menstrual cycle for about a year.

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: It’s usually when- unusually the lle- the- the- the roller coaster where we’re really feeling it, is in perimenopause, right? That’s when things really began to change. Well, basically- in the follicular phase, we’ve got the increase of estrogen levels, right? That kind of peaks at ovulation and then-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -starts to dip and go down. At that point in the luteal phase, you step into luteal phase, our progesterone levels begin to go up. Also, in the follicular phase, we got testosterone levels goin’ up too-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -naturally, but then everything starts to drop towards the end of luteal phase.

Dr. Justin Marchegiani: Right.

Dr. Mariza Snyder: And the pin on how fast those hormones are plummeting, really, dicta- reay kind of dictates P- PMS, right? The- the- that pre-menstrual cycle-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -is removing out of that. And so what I find that with women, if indeed we have a really sharp decline, or maybe they didn’t even necessarily have a big increase in progesterone to begin with, we’re gonna see things like migraines, we’re gonna see things like bloating, uhm, mood swings, a lot of those symptoms that we see around PMS. So that’s basically the physiology. And the only reason why we even get an increase in progesterone is if we actually ovulate. And-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -for some women, sometimes that isn’t even the case as well. So it’s really important to kind of- to look at all those things, to run tests. My favorite tests for looking in hormones is the DUTCH test.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: I usually recommend it during the luteal phase.

Dr. Justin Marchegiani: Okay, cool. So, you run ’em like a DUTCH Complete like arr- around day 19 to 22-ish?

Dr. Mariza Snyder: Things that like.

Dr. Justin Marchegiani: Kind of get that peak? And then do you run the- the month-long panels at all?

Dr. Mariza Snyder: I- I have not in the past.

Dr. Justin Marchegiani: Okay.

Dr. Mariza Snyder: But, I know how important those can be. Yes. And I usually- when I was testing, it was ever- I would do- I would test every quarter.

Dr. Justin Marchegiani: Yeah. Okay. Yeah, I mean I’ll typically run the month-long one, if there was more of a fertility case, but then, uhm- I’ll do a lot of a- you know, the snapshot in that- in that peak of a luteal phase, and I can’t tell you, I think uhm, you said it just right. I see so many women these days that are coming in with either mass- massive luteal phase defects where that luteal phase is just shortened or that progesterone’s just dropped out significantly, you know? Instead of 15 to 20 or so on that DUTCH test, they’re- they’re less than 5, even- and that’s really concerning. And then, that can approach these women into uh- maybe a- an estrogen-dominant situation. Can you describe what that is?

Dr. Mariza Snyder: Absolutely. So, estrogen- so- the- that’s really that you asked. Couple things about estrogen-dominance, we- you know, I get so many questions around this, you- you can actually have low estrogen and still be estrogen-dominant.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: So it’s really the relationship between estrogen and progesterone. And so often, given what we’re exposed to every single day, given our stress levels, so, not only lifestyle but also environmental, we still find that women tend to have more estrogen in the system than progesterone. And there are multiple factors, right? Progesterone could be stalling from our cortisol lab- you know, cortisol, the progesterone’s still. So we have- there’s a multiple facets but what we’re finding in a lot of women is that, just- just by the sheer fact of life that we’re living, estrogen’s gonna be- estradiol is gonna be higher than normal compared to progesterone. And, there’s a lot of thing that we can do about that for sure. And we can definitely get into that.

Dr. Justin Marchegiani: Yes. Yeah, very cool. And I’m even seeing a lot of women too that are at low progesterone but also low estrogen. Are you noticing that at all, too?

Dr. Mariza Snyder: Uh, that’s been me.

Dr. Justin Marchegiani: Oh.

Dr. Mariza Snyder: [Laughs]

Dr. Justin Marchegiani: And that’s just the hormone that just so depleted, right? Just-

Dr. Mariza Snyder: They’re so depleted. Yes. They’re absolutely depleted. And that has a lot to do with- I mean I- I find so often with women that it’s- a l- has a lot to do with the stress that that we’re living.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: You know, that’s very much like the key indicator, we just- we start burning out uhm- all of our hormones that we stopped creating the process where making them in a sufficient manner.

Dr. Justin Marchegiani: Very cool. I wanna highlight what mechanism because you know, you are upper cervical chiropractic specialist and we talked about chiropractic on the headaches side, and part of that can happen is, if there’s stress and inflammation in the spine by misalignment of poor movement, that’s gonna stimulate a lot cortisol to help with the inflammation. And we know, just for the listeners, cortisol pulls from progesterone, you mentioned that. So, when we get rid of the inflammation and we help the- the alignment and brain communicate better with the spine, that can decrease that progesterone still ’cause we’re not pulling from the cortisol as much. Is that sound right?

Dr. Mariza Snyder: It does. I mean, you also have to- I always tell people, you can’t chiropractic a green smoothie your way out of chronic stress.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: ‘Cause it’s, how you perceive the environment. If you’re continuing to create an environment, you know, I was talking about women being Rushy- having Ru- Rushing Woman’s Syndrome.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: If you are raising from one thing to the next, you’re gonna constantly being in a situation, this not- not medical terms, but I call it the Clutch the Pearls syndrome.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Where you’re constantly clutching the pearl. [Chuckles]

Dr. Justin Marchegiani: Exactly.

Dr. Mariza Snyder: So, if you’re constantly in that state, the- there’s gonna be no doctor that I know that there’s an- and there’s no supplement.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: There’s no green smoothies, there’s no nothing that’s really gonna-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -get our body back on track until we change the way that we are behaving at- in accordance to our environment.

Dr. Justin Marchegiani: Totally. That’s why a good functional medicine doctor, they’re gonna investigate the physical stressors. They’re gonna investigate the chemical stressors, that could be like you mentioned, the- the chronic stress state, the sleep, the poor food, the inflammatory food, the infections. The hormones maybe coming from the environment from food and pesticides, a d glyphosate, that totally make sense. And you mentioned the DUTCH testing. And that’s interesting because a lot of people I find at least more on the medical side I- I find it, they look at the hormones like the female hormones, the male hormones but, a lot of times they missed the adrenal hormone components. And what’s- what- [crosstalk]… yeah- yeah. Can you talk a little bit more about how the adrenals and why they’re so important to f- healthy female hormone function?

Dr. Mariza Snyder: Absolutely. So I- you know, I- you know, we necessarily see, you know, I was thinking about the- adrenals being the receivers of information. You know, they- they have a very important job, and that is to ensure, that is to listen to what the brain says, and you always talk about the Hypothalamic–pituitary–[adrenal] axis.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: Right, that relationship between-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -what we’re receiving, the HDA access-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: And- and that real- that information that’s related to the adrenals. And I- you know, I always talk about menopause and perimenopause being more of a stress condition than it is more of a hormone condition.

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: Uhm because of our- if our- if our adrenals aren’t supporting that, if our- if our chronic stressors are under-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -chronic stress under control, we’re going to throw those hormones out because it’s all interconnected.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: And at the end of the day, Dr. Justin and you know this more than I do, uhm, is that we are hard wired for survival.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: That- okay you had 2 jobs biologically that we’re supposed to do. 1, survive-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -and 2, pass down genes.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: So, reproduce, right? So kinda new- a new baby coming on the way, right?

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: And then when they have babies, well then you are an evolutionary success. So, our bodies, that’s the purpose. Now, hard-wiring towards survival means that we have to give up a lot of other thing. Our digestive system, our reproductive system takes a hit. You are a great thyroid expert, you know that a thyroid definitely over compensates for what’s going on as well.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: Uhm, but I wouldn’t necessarily see- I mean, and yes, you can definitely create adrenal fatigue over time. But you-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -think- take the wild for the adrenals to finally-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -say, “Enough is enough!”.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -“…I cannot take this anymore”, but I find that where we really gotta focus our efforts, is right here in the limbic system.

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: Uhm, that’s where we need to change the che- the chemical conversation. Because if that HPA access is continuing to up-regulate every single day-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Well, the adrenals are just like, “Dude, I’m just doing my job”.

Dr. Justin Marchegiani: Right.

Dr. Mariza Snyder: “…I just gotta- I gotta release this adrenal- this adrenaline, I gotta release this cortisol”-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -“…that’s my job, until one day, I am like, ‘I can’t do my job anymore. I can’t handle it'”. So, I would say that really, I always wanna work on the HPA access first-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -before I’d even begin to look actually at adrenal health. So, often I see that women have an up point of cortisol, maybe DHA is dysregulated, but the adrenals are still high functioning-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -still a while. Uh, so, that I usually wanna get to that root first which is I find right here.

Dr. Justin Marchegiani: Yeah. Very interesting. And it- it- it could be just semantics. I’ll look at the HPA access is like the person in the old horse and buggy that- that’s- that’s whipping a thyroid horse. The thyroid horse-

Dr. Mariza Snyder: Yes.

Dr. Justin Marchegiani: -[crosstalk] the adrenals, or the ovaries, so yeah, make sense-

Dr. Mariza Snyder: [Crosstalk]

Dr. Justin Marchegiani: …yeah, or the thyroid, or you can even go and- and-

Dr. Mariza Snyder: Or your gut, or your poor darn liver.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Our liver is just like, “I can’t pour out enough glycogen, like I…”, you know, that’s where we get diabetes. We’re getting-

Dr. Justin Marchegiani: 100%. So, you’re talking about really getting the communication and these feedback loops dialed back in, can we just go into some strategies, what are things that you are doing with the patients so that people are, you know, reading your work, what are the top 3 things and- and- and if you wanna qualify them with certain situations, that’d be helpful too.

Dr. Mariza Snyder: Absolutely. So, you know, we’re talking about kind of that- err- I think that first of all we just talk about the unexpected uhm, unexpected solution to health and radical self healing is awareness. You know, if you are not aware that you’re putting crap into your body, it’s really difficult to make those changes.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: If you’re not aware that you’ve had a gluten intolerance, you’re gonna probably still consume- eat glut- eat-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -gluten, right?

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: And if you’re not aware that you are running from one thing to the next, and that you’re living in a high stress situation, you’re just gonna keep doing what you’re doing. So, I think the first step really is self-awareness. Recognizing that something is not right. And I know-

Dr. Justin Marchegiani: Right.

Dr. Mariza Snyder: -for me, I thought I could green smoothie my way out of chronic stress-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: I also gonna get chiropractic my way out of chronic stress.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: And it didn’t work. I had to figure out that I kept- I had this operating system, this feedback loop that was firing-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -whether or not I knew it or not. So-

Dr. Justin Marchegiani: Yep.

Dr. Mariza Snyder: -I think some of the most important things is 1, we definitely live in a time of isolation. I’m so grateful for this technology that you and I-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -could be talking right here.

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: What would be even better is if we were right together, right?

Dr. Justin Marchegiani: Yes, totally.

Dr. Mariza Snyder: So, uh, having friends on speed dial, having people and family in your life that you can give hugs to, that you can- you can, you know, connect with, kind of boost that oxytocin level that dose that cuddle hormone-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Just being connected with people is number 1. Number 2, I love the power of plant-based medicine, so-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -I love essential oils-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: I think havin’ a tool, like a little oil like this-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Uhm, Bergamot and Lavender, we know-

Dr. Justin Marchegiani: Uh-huh.

Dr. Mariza Snyder: -research, time and time again, to lower serum cortisol levels, lower blood pressure and lower pulse point, but most importantly, they disrupt the cycle, from sympathetic to parasympathetic in that HPA access.

Dr. Justin Marchegiani: Okay.

Dr. Mariza Snyder: And I wanna disrupt the cycle.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: I wanna get ’em to habit. So not only does the chemistry by breathing the oils in-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -go to the limbic brain- limbic brain to disrupt the cycle. But the intention of you-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Rubbing that oil, makin’ a decision like-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -“Hey, I feel…”-

Dr. Justin Marchegiani: Be aware.

Dr. Mariza Snyder: -“…like I’m having a moment”, yes.

Dr. Justin Marchegiani: You’re aware.

Dr. Mariza Snyder: And that begins to change the cycle as well.

Dr. Justin Marchegiani: Very cool.

Dr. Mariza Snyder: I’ll do thing- Yeah?

Dr. Justin Marchegiani: Go on. Go ahead.

Dr. Mariza Snyder: Oh, I got some other things. Uhm, I do love adaptogenic herbs-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: I do love Ashwagandha, I love Rhodiola, I- I love Holy Basil, any of them- all of them, it depends on that- I think you- I think testing is important to kinda understand-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -what’s going on. They do love those adaptogenic herbs, ’cause they also work on the limbic brain in the HPA access.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: I also think food plays a big role. I know I did say that you can’t bring some the- you’re out of chronic stress, but man, those important nutrients-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -can really help support the body if indeed you’re just in scenario right now where you’re like, “You know what Dr. Mariza and Dr. Justin, I hear you, but right now I’m- I have to live in this emergency state for a little bit”. You know-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -life dictates that for me. So those are some of the big things that I normally recommend for people than breathing, exercise, yoga, just pausing for a moment throughout the day, just that self-awareness, and then, self-care. I think self-care is the game changer. Uhm, so those will be some of the lifestyle techniques that I- I always recommend to women to start implementing. If they’re looking to start with that root thing, that HPA access, so that we can start to change the conversation that’s happening inside of the body.

Dr. Justin Marchegiani: Interesting. And that, when you’re looking at people, and let’s say you’re giving essential oils that are proven to lower cortisol, right?

Dr. Mariza Snyder: Mm-hmm.

Dr. Justin Marchegiani: Are- are- are you concerned if someone already has lower cortisol, or are you gonna be using other adaptogens that may, you know, have an up and down kind of bump in the direction. So, how are you evaluating that when you’re making specific recommendations?

Dr. Mariza Snyder: Absolutely, so yes. Could we have a situation where someone has significantly like at that point they de-regulate cortisol levels to so- such a degree-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -that they have- now they have lower cortisol levels? Yes. And so- and those ins- instances, I’m now looking more at and clearly, there are essential oils you can help boost cortisol, things like Rosemary, peppermint and citrus oils. So, we’re looking at a different response, and then yes, looking at different adaptogenic herbs to make those changes, that kinda- to heal the body’s- when we get you-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -to the base line, but also making those lifestyle changes as well. I mean, if in-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -deed, just grab in an oil just to have that moment for your-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -self. Uhm, I think- but that’s- it’s- that is important, it’s nice-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: Uh, especially they having a hard time going to sleep at night, uhm-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -but yeah, I mean, I think that the areas- I mean in- in all instances, everything is case by case.

Dr. Justin Marchegiani: Interesting. Is there any herb that you recommend that you feel just a really good multi-task, or where your cortisol could be low, and may give you a little pick me up, and it could also be a little bit high and you could be stressed that can kind of bring you down. Is there anything in that category?

Dr. Mariza Snyder: I think Rhodiolas would your- your go tea there. I like it the most, I feel like it- it really- and not only have support mitochondrial function, which-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -I love, uhm, but it also can meet you both ways. I think more than Ashwagandha, uh, Rhodiola really is one of those adaptogenic herbs that will kinda give you what you need.

Dr. Justin Marchegiani: Okay, cool. I wanna go a little bit- I’m gonna go a little bit deeper here. Can we talk about some of the nutritional compounds that are in these herbs? Are you aware of some of the- uh you- we talked about the adaptogenic components, other nutritional compounds that we’re also getting from some of these essential oils that are helping us, as well? Kinda like vitamins and minerals or polyphenols, what’s happening there?

Dr. Mariza Snyder: Yes, essential oils aren’t nutrition. Uhm, some of them can definitely have antioxidant benefit especially like citrus oils-

Dr. Justin Marchegiani: ‘Kay.

Dr. Mariza Snyder: -but I don’t necessarily consider them nutrition-

Dr. Justin Marchegiani: Okay.

Dr. Mariza Snyder: -I’m so much as like consider them as being- uhm, it’s powerful- kind of- uh, organic chemistry, right? Uhm-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -really can work in the body and aid in the body. So, nutritionally, I usually still lend to a p- uh- plant-based nutrition or supplementation. You have someone is-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -deficient in magnesium, well, we gonna get them with some magnesium.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: And B-Vitamins then activated B-Vitamins are gonna be what I recommend. But usually when I use essential oils for most importantly, is cre- is- is- is to bridge the gap for the lifestyle changes that we know we should be doing, we just aren’t doing. So, for instant, if we are going to- if we’re having a hard time going to bed every single night-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -because, we cannot shut up brain, or-

Dr. Justin Marchegiani: Totally.

Dr. Mariza Snyder: We- we just- we just prefer to work instead. Whatever that maybe, you’re in your, you know, you’re in your phone, you’re on your iPad, or whatever that maybe, like I was just in the phone with my grandma today, one of my- I go look on both my grandmas for- for different reasons, but-

Dr. Justin Marchegiani: Mm-hmm, mm-hmm.

Dr. Mariza Snyder: – my uhm- my little Mexican grandma, my mother’s mother, she- I was- I called her and my grandma is like, “You know, everytime- every night before we go to bed, I just watch you. I watch you before I go to bed”, and I’m just like, “Okay”. I’m like, “Well, do you learn anything from me?”, and she’s like, “Yeah, I don’t know at all”, you know, she’s [laughs]. I think, “Grandma, you shouldn’t be on your iPad before bed”. Look [laughs]-

Dr. Justin Marchegiani: Totally, totally.

Dr. Mariza Snyder: Just killing her- anyway, it’s just a really funny moment, but I think so many people like my grandma where they’re on, YouTube or they’re on- I don’t-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -even know where she’s watching, we have no idea. Uhm, but, having a ritual where you’re utilizing the essential oils, like the process of Lavender, Bergamot, Cedar Wood-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -clary sage, whatever those oils are, getting into the habit of creating this behavior, but also knowing that that chemistry is helping to really calm down the brain as well ’cause they’re all very common essential oils. So that’s kinda how I love to leverage them. How can we use them to set a- set a mo- uh, evening ritual where you’re calming down the brain and going to bed. How do you use them to go to the gym every single day? Like, I love peppermint and wild oranges, an instant energizer body. How do you use them for productivity and- and energy and alertness, and working memory. Right, a combination of peppermint-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -Rosemary and Frankincense, that’s gonna do that for you. So I think when it comes to these lifestyle changes, the self-care, if we have these oils that can punctuate how we live our life, that’s how I love to use them in aiding in the- in the daily decisions that we make, either, hopefully you start your day with great decisions that lead to more great decisions, and you’e leveraging that chemistry to just have a really great experience.

Dr. Justin Marchegiani: Very cool. Is there anything you used synergistically outside of diet and lifestyle? Are there any of nutrients that you will use supplementally synergize with essential oil? Uh- I’m just kinda throw it out there, maybe like magnesium and lavender, or something like that, is there anything you seen clinically?

Dr. Mariza Snyder: Yeah. Uhm- gosh, that’s a good question. You know what, I- I- no, and clinic- clinically, yes, I guess maybe case by case for me-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder:-I don’t know if there’s a lot of research where we’re seeing a lot of the combinations of herb-herbs, and, I mean oils, or s- or vitamins and minerals and oils. Uhm, we- I- what I do know is that yeah, like when you’re heading to bed at night, let’s say it’s lavender, and maybe you’re using something like melatonin or maybe-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -something like uhm, eating cream rose, I think-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -that those have a really profound impact. UHm, let’s say that you are using uhm, like- like, I recommend a lo- I recommend turmeric, I recommend omegas, I recommend uhm, something for cognitive function in particular but I also know that rose mary, the chemical constituent rose mary which is 1/8 ___[22:06]-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -actually helps to increase acetylcholine in the brain. And so [crosstalk] as well. Yeah. So, pair as well as, I think important supplements that can help um, boost brain function. But just breathing in rose mary will inc- will literally increase working memory by 75%.

Dr. Justin Marchegiani: Awesome.

Dr. Mariza Snyder: Right there in there, without taking omegas. But you should be taking omegas anyway. DHEA, so- so just- err- uh- DHEA- DH- err- gosh I’m having a- anyway, the point is this, when you’re taking-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -those omegas, you’re boosting memory and- and brain function. So, I- I guess in a sense, I’m usually telling people to be consistent with them, uhm, so that you’re getting the response that you want, but I also- I’m recommending supplements, so it feel like when it’s- we’re coming to long ___[22:47], and-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -really changing those biological processes, then we have that in place as well.

Dr. Justin Marchegiani: Okay, very cool. Alright, I got some rapid fire questions here. I’m putting you on the spot, you ready?

Dr. Mariza Snyder: Alright. Yeah.

Dr. Justin Marchegiani: Alright, you already said 1, I- I’l answer it for you. Memory, your favorite essential oil sounded like it was Rose Mary-

Dr. Mariza Snyder: Rose Mary, yes.

Dr. Justin Marchegiani: Okay. Good. Anxiety, favorite?

Dr. Mariza Snyder: Anxiety. Uhm, lavender, lavender and vetiver.

Dr. Justin Marchegiani: Good. Depression?

Dr. Mariza Snyder: Depression. Oh my goodness. Uhm, frankincense, Meliss- I- I’m giving you another one. Frankincense, Melissa and citrus oils.

Dr. Justin Marchegiani: Excellent. Uh, pain in the joint?

Dr. Mariza Snyder: Wo- I would say well, camphor is really what I’m looking for, but camphor can be found in winter green, uhm-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -I also love copaiba, uhm, for-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -it’s connection with the uhm- the- oh my gosh, the- kind of work similar to CBD so it connects with the CBD receptors it’s CBD-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -receptors in the body-

Dr. Justin Marchegiani: I know what you’re talking about, the- the- that endocannabinoids system, that-

Dr. Mariza Snyder: Yes.

Dr. Justin Marchegiani: -makes sense.

Dr. Mariza Snyder: Yes. exactly.

Dr. Justin Marchegiani: What about brain fog?

Dr. Mariza Snyder: Uh, brain fog. So, I love Rosemary. Rosemary, peppermint, frankincense, same kind of concept there.

Dr. Justin Marchegiani: Good. How about something like an ear infection?

Dr. Mariza Snyder: Uh, ear infection. So, I love Tea Tree Oil. So, Tea Tree Oil is a great antiseptic, antibacterial, but le- so my go tea for- for an ear infections is Tea Tree, Basil and lavender around the ear, diluted at around 25% dilution.

Dr. Justin Marchegiani: Okay. And is there any other uhm, chronic issues or situations that you get asked a lot, that I didn’t mentioned yet?

Dr. Mariza Snyder: Gut-

Dr. Justin Marchegiani: Oh!

Dr. Mariza Snyder: -all day, everyday.

Dr. Justin Marchegiani: Woah.

Dr. Mariza Snyder: [Laughs]

Dr. Justin Marchegiani: [Laughs]

Dr. Mariza Snyder: Right? So- uhm, so in- you know what, gut is- it’s a whole nother conversation, and it’s- it’s- it’s- it’s actually a hundred different conversations.

Dr. Justin Marchegiani: Totally.

Dr. Mariza Snyder: So, let’s say you are having an acute gut issue, maybe you decided to eat pizza on a friday night and you knew better, and you didn’t-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -take your enzymes or, you took- you didn’t take- you took your enzymes but still it didn’t matter-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -because you have gluten and- uhm, and dairy sensitivities. Uhm, so I love a blend- it’s a blend- it’s a combination of phenyl, peppermint and ginger.

Dr. Justin Marchegiani: Oh. Yeah?

Dr. Mariza Snyder: And I’m not saying that those oils are gonna cure what’s going on there, but at least it’s gonna lessen the acute symptoms.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -and that’s happening inside of the gut. And so, I just make up a du- a little roller like this, 10 to 15 drops of each.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: …over the stomach, and those 3 oils have been researched, particularly because of the herbs, the chemical constituents in those oils have been really, calm down things like bloating, constipation, diarrhea, and- and just in pain in the gut that could be happening in a small-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -and large intestine.

Dr. Justin Marchegiani: Yeah, and a lot of those oils too, stimulate uhm, acid production, enzyme production naturally as well. So, you’re- you’re kinda get in the body to pinch in help as well?

Dr. Mariza Snyder: Yeah, and peristalsis as well. So removing-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -through, yeah. And, another one, I mean, I traded migraines and headaches for so many years.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: I do love, uhm, a combination of lavender, peppermint and frankincense, that’s kind of my power combo-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: Again, in a roller, 10 to 15 drops of each, uh- you know, for me, it’s- it’s- if you can catch that migraine on time, it’s always cervicogenic for so many people.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -so always start back here, uhm, and just get those oils on, you know, every 30 minutes, uh, so that you- maybe- so that, that’s the option instead of uh- a non -steroidal anti-inflammatory.

Dr. Justin Marchegiani: That’s great. And you mentioned earlier, we talked about luteal phase defect and our low progesterone in that last half of the cycle, is there anything essential oil-wise that you do to help support that luteal phase, that low progesterone/ PMS, hormonal environment?

Dr. Mariza Snyder: Absolutely. So, there, my gotu oil I called the “Beyonce” of hormonal oils-

Dr. Justin Marchegiani: [Laughs]

Dr. Mariza Snyder: [Crosstalk]. I have a blend, it’s called my superwoman blend, and it’s-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -actually what this is right here. This is what I’ve been holding up all day.

Dr. Justin Marchegiani: Oh, cool.

Dr. Mariza Snyder: And they’re designed for- yeah, it’s kinds luteal defect, helping to boost progesterone levels. So, the 2 gotu oils for boosting progesterone levels are gonna be, uh, clary sage and thyme. Now, thyme, not the sexiest smell in the world, but you can-

Dr. Justin Marchegiani: Right.

Dr. Mariza Snyder: -definitely make up a blend like that-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -on the bottom of the feet or right over the ovaries. This one doesn’t have thyme, but it has geranium which can also do that. What I also love about geranium is- it helps the liver in the de- in the pa- phase 1 and phase 2  of the detoxification-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -pathway, it helps to breakdown uhm estrogen metabolites. So I do love geranium for that. So, this is 12 drops of clary sage, 10 drops of lavender, 5 drops of geranium, 5 drops-

Dr. Justin Marchegiani: Ah.

Dr. Mariza Snyder: -cedar wood, it’s a- it’s a blend; and 4 drops of lengling, and so, applyin’ it over the ovaries or right here, ’cause remember-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -oils definitely goes straight into the bloodstream.

Dr. Justin Marchegiani: Exactly.

Dr. Mariza Snyder: Right here in the wrist, I love it on my neck as well, uhm, and just a couple times a day, uhm, it’s also great for mood support and it’s great for cravings and energy. So, it’s kind of a multi-faceted essential oil, but I have women using it for period, their periods and PMS all the time, all over the country and all over the world, and with great success. So I love this one.

Dr. Justin Marchegiani: Very cool. Very cool.

Dr. Mariza Snyder: Yeah.

Dr. Justin Marchegiani: Now, one of my biggest pet peeves, just ’cause this could be a hormonal stressor as well, and it just drives me crazy, is when people have- when guys either have like a strong, uhm, cologne, or womens have a s- have a strong perfume on, what can be an essential oil alternative, you know, for- for a woman or for man, that can kinda still give ’em that- that smell that they want but it wouldn’t be non-toxic and drive people crazy?

Dr. Mariza Snyder: Oh, silly. I have a lot of perfume blends. If I, you know- it depends on the person. The-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -Superwoman blend for women, a lot of women wear as perfume-

Dr. Justin Marchegiani: Great.

Dr. Mariza Snyder: -’cause it smells great, and who doesn’t want side-benefits, right?

Dr. Justin Marchegiani: Yes. Yeah.

Dr. Mariza Snyder: That’s what I love. But with guys- so, you think about most colognes, but ___[28:04] is vetiver, and-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: Vetiver is a powerful neurological essential oil.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: And fortunately, you’re getting a synthetic virginning cologne, and so- uh- you know, uh- vetiver, citruses, myrrh’s, frankincense, sandalwoods, those are all oils that are used in colognes. I don’t have a very specific male cologne recipe  in my ha- in my head right now, but I- there’s a lot of them out there.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: And a lot of guys use them. My husband made up his own thing-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -I have no idea what’s in that blend. But he does his thing, and then for me, I’m obsessed-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -with jasmine and rose. So, I wear a combination of jasmine and rose. Jasmine, what’s- what’s really interesting, is that jasmine’s been researched to help women overcome postmortem depression. Uhm, it’s also a libido booster-

Dr. Justin Marchegiani: Okay, cool.

Dr. Mariza Snyder: -and then rose is just a really powerful, beautiful essential oil so, I- that combo is just so beautiful to me, my husband loves it. Jasmine’s intoxicating. And so, a lot of women really grabbed a taste towards jasmine, yeah.

Dr. Justin Marchegiani: Very cool. Now-

Dr. Mariza Snyder: Yes.

Dr. Justin Marchegiani: -do you manufacture your own essential oils or do you have certain lines out there that you like or you think are really high quality?

Dr. Mariza Snyder: I think- you know, I think when it comes to the “I do not manufacture”-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -oh my goodness, the- the- the- the amount of effort and time and research that goes-

Dr. Justin Marchegiani: Totally.

Dr. Mariza Snyder: -into the oils is just- just- profound. Uhm, I- when I always is when you’re researching the company, and I do have a company that I prefer, but make sure that that company, they- they tell you where they’re sourcing their oils. Where are these oils coming from?

Dr. Justin Marchegiani: Hmm.

Dr. Mariza Snyder: Each and everyone of those oils that I mentioned a minute ago, and that superwoman blend, come from a different country-

Dr. Justin Marchegiani: Okay.

Dr. Mariza Snyder: -all over the world. And, different, very small batch growers are growing those in- in a very, you know, in an organi type of setting. Then, once those oils are produced and harvest in a sustainable way, I wanna know how they’re tested. Do they use gas chromatography, are they using spectroscopy, are they using chirality testing, are they using microbial testing, how are they testing these oils, and, as third party uh- laboratory should be testing the oils to really guarantee their efficacy, and if it’s a really great company, they will be a lot number on that label, where you can pull up the testing of that batch. So-

Dr. Justin Marchegiani: Oh, very cool.

Dr. Mariza Snyder: -that’s what I’m looking for when I’m looking for oils. Because if you’re trying to use these re- ther- therapy to benefit, well then you just don’t wanna put crap on your body.

Dr. Justin Marchegiani: Got it. Is there any s- is there any specific essential oil companies that you know of that- that meet those standards you just mentioned?

Dr. Mariza Snyder: Yes, there are couple. My gotu favorite is Doterra. I’m a big fan of-

Dr. Justin Marchegiani: Okay, Doterra, cool.

Dr. Mariza Snyder: -I’m a Doterra girl.

Dr. Justin Marchegiani: Cool.

Dr. Mariza Snyder: And uhm, I’ve been using them for years, I’ve been recommending them millions of people as well with great success, so I feel really confident with the quality control that they implement.

Dr. Justin Marchegiani: Awesome, very cool. And I know, today, we are really getting into a lot of the essential oils and the hormone connection which is great. And this is kind of I think a perfect segway for you to kinda dive in and just keep people a little sneak preview about your book which is gonna be I think a more in depth version of this conversation.

Dr. Mariza Snyder: Absolutely. So, I have a new book comin’ out, I don’t know when this is airing, but do have a new book coming out, it’s called “The Essential Oils Hormone Solution”. And it literally, not only do I go into the “Why”, the- the- the chemical, biochemical “Why” of what’s going on in the body-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: So often women are like, “Well, what do you have for menopause?”, and I’m just like, “Well, what about menopauses that concern?”, you know? And- and what if- what if it isn’t menopause at all, maybe it’s something else? And so, understanding the- the chemical implications, what’s going on with hormones, then giving women oils, protocols, self care, it’s all built in, and then I have a 14-day hormone reset program that contains my hormone trifecta which is a combination of food, oils and self care. And when you put those things together, it really is magic. So, that is what the book entails. 400-pages.

Dr. Justin Marchegiani: Woah!

Dr. Mariza Snyder: It’s a very big book, with 40 pages of bibliography. So, I did hundreds of hours of research for this book.

Dr. Justin Marchegiani: That’s amazing.

Dr. Mariza Snyder: Yeah.

Dr. Justin Marchegiani: And then, the book’s called what, “The Essential…”, can you repeat it again?

Dr. Mariza Snyder: Oh, yeah, “The Essential Oils Hormone Solution”. Here is this what it-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -looks like, and it’s on-

Dr. Justin Marchegiani: Perfect.

Dr. Mariza Snyder: -it’s on Amazon. It’s selling like “Hot Cake” which makes me so-

Dr. Justin Marchegiani: It’s already out now?

Dr. Mariza Snyder: -happy. Yes. Well, it’s- it’s right now, it’s for pre-order but people were buying it.

Dr. Justin Marchegiani: Great. I’m gonna put the links- the Amazon links down below. So, if anyone’s listening to this on the iTunes or YouTube, just click below and you’ll be able to get it. That’s awesome. Is there any other information at all you wanna share with the listeners here before we wrap up?

Dr. Mariza Snyder: I would just say, I think the biggest message that you and I probably bring to table is that, you really have- you really are the CEO of your health. You know, we have a- there’s a lot of great practitioners out there like Dr. Justin and myself who can really guide you on this path, but just know that there is- there’s ownership for you. And that, you don’t have- you know, you don’t need to be told that you’re just gonna have to live with this disease or this condition, but there’s definitely a way out, it’s just a matter of deciding that yes, “It’s time for me”, and just reaching out to people like ourselves, be- listening to Dr. Justin’s podcasts, because that’s exactly what we’re here to to do is to really navigate that journey for you, but you’re making the best decisions for health.

Dr. Justin Marchegiani: Very cool. And if listeners wanna get more information about you, where is the best place to go?

Dr. Mariza Snyder: So, I have a podcast myself, it’s called the Essentially You podcast, and it’s a great place to find me, it’s everywhere. Uhm, I have other books as well, but then, my website is, I have fun, awesome little chit-chit there, on the top 5 oils for hormone balance, you guys go and grab that, and then if you do pre-order the book, I have $300 worth in bonuses that instantly gets delivered to your inbox, so you can get started right away. So, even if you’re like, “Man, I just- the bo- book isn’t gonna be here for a couple weeks”, no worries, the bonuses will hook you up, until a book arrives.

Dr. Justin Marchegiani: Very cool. And just for the listeners, there’s a silent “Z” in that name here. D-R M-A-R-I-Z-A-[dot].com, and I see a cool little optin’ on the top 5 essential oils for hormone balance. So, while you’re up there, feel free and get that. Dr. Mariza, anything else you wanna add?

Dr. Mariza Snyder: That- I think that’s it, I think we covered a good amount of information. Dr. Justin, thank you so much for the great questions, it was such a pleasure to be here.

Dr. Justin Marchegiani: Thanks to in the part of the podcast. Thanks Dr. Mariza!

Dr. Mariza Snyder: Mm-hmm.


The Essential Oils Hormone Solution 

Improving Gallbladder Function with Functional Medicine | Podcast #216

Digesting fat is so important for one’s hormone growth and for healthy cell membranes as every single cell has a lipid bilayer. If one wants to be a good fat burner on a ketogenic template, it is really important to have great gallbladder function.

In today’s podcast, Evan Brand and Dr. Justin Marchegiani talk about utilizing functional medicine principles and assessment to figure out how one’s gallbladder is doing. Listen as they talk about what can one do about it, the common gallbladder symptoms, root cause solutions, and how can one get better from these symptoms. Stay tuned for more!Evan Brand

Evan Brand

In this episode, we cover:

00:35    What is Gallbladder?

04:47    Consistency of Chewing Foods

08:16    Bile Surgeries

14:18    Autoimmune Issues that Affect Gallbladder

17:28    The 3 F’s of Gallbladder Issues

20:26    Some Advises if Your Gallbladder was Removed

26:32    Comprehensive Stool Test


Dr. Justin Marchegiani: Hey there, it’s Dr. Justin Marchegiani, welcome to today’s podcast. We’re gonna be talking about utilizing functional medicine principles and assessment to figure out how your gallbladder is doing. Also talking about what we can do about it, what are the gut- what are the common gallbladder symptoms, what are root cause solutions, and how we can get you better. We know, digesting fat is so important for your hormone growth, for healthy cell membranes. Every single cell has a lipid bilayer. And also, if you wanna be a good fat burner on a ketogenic template, it’s a really important we have great gallbladder function. So Evan, welcome to today’s podcast, man!

Evan Brand: Hey man, thanks for having me.

Dr. Justin Marchegiani: Awesome. Well, let’s dive in brother. I’m excited to- to dive in. So, first off, let’s just first dive in just to kinda physiology 101: what is the gallbladder? Why is it even so important? So, off the bat, gallbladder is kinda in this upper right quadrant here just beneath the rib cage, ‘kay? If it’s tender in that area like they’ll do a- a palpation that’s called Murphy sign, uhm, in that area where they’ll look for tender type of gallbladder issue where the gallbladder’s inflamed. But the gallbladder, it- it basically concentrates bile at about a 15 times above than the common hepatic bile duct in the liver wood. So when you’re having your gallbladder removed, that common hepatic bile duct up in the liver just drips bile all the time, it’s not specific, it’s not during a fatty meal, just kinda hits, and you can definitely have some bile acid diarrhea issues. When you have a gallbladder it concentrates that bile 15 times and then allows it to come out and time it, it- it squeezes, it contracts, and s- puts up that bile especially during a fatty meal ’cause you have these hormones in your stomach when that food- when that uhm, kind, that mixed up food in your stomach gets released into the small intestine. Uh, the nice acidity of that stimulates this uhm- neuropeptide called cholecystokinin or CCK for short. And that cause the- the gallbladder to contract and stimulate all these bile release which helps with fat digestion. If we don’t have a gallbladder, we’re not gonna be able to breakdown fat optimally through biliary concentration.

Evan Brand: Yup. So, you’re in to that fast, I’m just gonna repeat it so it gets into some people’s heads.

Dr. Justin Marchegiani: Mm-hmm.

Evan Brand: So, you say, when your- you put food down the hatch, especially fat, it enters the digestive tract, the body says “Okay, boom. There’s fat in here now, I’m gonna start making CCK”, and that comes from your duodenal, and I believe the jejunal as well, and then- it- to respond to the CCK, then the gallbladder goes “Oop, CCK is in the neighborhood, now I’m gonna release my stored bile because we’ve got fats to take care of”. So then the bile, or they call gall, will start working on these fats and then turning those fats into usable fuel.

Dr. Justin Marchegiani: Yeah, think of emulsification is like you have a greasy pan, and you put a drop of like soap, right, like some- some dish soap like dawn dish soap, and it kinda breaks it up, it emulsifies it. Think of that’s what’s happening if you got this greasy pan in your stomach, which is all the fat in your stomach going into your small intestine, that emulsifies it and allows your body to break it down and absorb it. It goes in these little things that form uhm- a- uh- a- a- a micelle, and that allow it to get into your body and be able to utilize it. Now, going up one kind of marker is hydrochloric acid levels. This is even important, this is more important because hydrochloric acid stimulates, it lowers the pH, and a nice low pH triggers cholecystokinin. So, we also need good pH function, good hydrochloric acid function and then that then, in the small intestine really gets the bile going, and then we also have some enzymes in the pancreas called lipolytic enzymes, lipase enzymes that also help with the pacre- with the- with the gallbladder in the- in the bile digestive process.

Evan Brand: Well, you make a good point, ’cause when we jump into this conversation, if we’ll look at the whole digestive cascade, as a big row of dominos, when you get to CCK and you get to the gallbladder, you’re really talking 3 or 4 dominos down the list but it’s good that you went upstream first to the mouth, where that’s where you’re chewing your food – hopefully you’re chewing your food, you’re not rushing through your meal. That’s why I don’t like things like chipotle, I enjoy the food itself, but it’s all soft, it’s mushy, meat and rice and guacamole, and you can just shove it down the hatch and you really have to chew the stuff. So, if I eat a soft meal, I still try to be very condescend about chewing, chewing, chewing, chewing, tellin’ the digestive system, “Hey, something’s coming down the hit- down the hatch”, but, you make the point about HCL. It’s why it’s so important when we- uh, talking about gallbladder symptoms which we’re getting to in a minute, to look for, and to treat if you have them, H-Pylori, and other infections ’cause, if H-Pylori is reducing your HCL levels, well, you can’t go straight to the gallbladder. I mean, you- you can, you can take bile salts to help it, but you didn’t fix the root cause, it was H-Pylori.

Dr. Justin Marchegiani: Exactly. So, kinda highlighting, we went from the gallbladder. What’s happening at the gallbladder, upstream to HCL, and that- that also activates other enzymes in the stomach called pepsin, and also gets the pancreas producing lipolytic fat breaking down enzymes, and then proteolytic protein breaking down fat enzyme, it’s- it’s very rare that you just have fat by itself, typically fat, protein and cholesterol tend to come together. And then, up one stream above is the chewing part. We wanna make sure we’re chewing our food at least 32 times, that’s about one chew per tooth, right, you have 32 teeth, so think of 32 chews, 32 teeth. And in general, getting your food’s to like an oatmeal like consistency, like- if you’re having a food that’s kind of more predigested like a chipotle meal, you gotta just make sure you at least chew to that good oatmeal-like consistency, and try to be in a relatively stress-free environment because the parasympathetic nervous system is really important for HCL secretion, thus enzyme secretion, and thus, uhm- bile secretion because we need that nice acidity, we need the enzymes, we need the digestive secretion. And for a sympathetic state, all that blood flow is going out extremities, our arms and our feet to run, fight and flee. So, it’s very important that we have good parasympathetic, so good breathing, gratitude, being in a quiet kind of relaxed setting to start our digestive processes.

Evan Brand: You know, I was trying to find some research on this, I am just gonna guess based on the mechanisms we discussed, that people on acid blocking medications probably have more issues with gallbladder. Would that make sense, ’cause let’s say you don’t have H-Pylori infection but you’re on an acid-blocking drug, isn’t that gonna just down-regulate this whole process we’re talking about?

Dr. Justin Marchegiani: Yeah, we need good acidity to trigger that CCK. So, that totally makes sense, right? And then we need- to be able to break down god fats. What are good fats? Well, we have our mono unsaturated fats are gonna be things like olive oil, avocado oil, and then maybe even some nuts and seeds. We have more saturated fats which are gonna be animal products, right? Grass-fed beef, uhm- any of our like, you know, fish, chicken, beef stuff, you’re gonna have omega-3 fats which are on the polyunsaturated category. Omega-3 is more polyunsaturated, and then you also have your saturated coconut oil which I think is your only plant fat that’s saturated, maybe that and palm I think are the only 2 big saturated ones that are plant-based. So, we have our saturated fats, right? Coconut, plant-based fat- coconut, and animal-based fats. We have our mono-unsaturated which typically are gonna be uh- a lot of the olive oil, potentially avocado oil, we have our polyunsaturated, a lot of times which are fish, and then maybe some of the nuts and seeds kind of fit into that monounsaturated category omega-6 kind of category as well. And then we have our uhm- Vitamins-A, D, E and K, “ADEK”, these our fat-soluble vitamins. So if we don’t have good bile-support, we’re not gonna be able to break fat down by the minute which is really good for our uhm thyroid function, it’s good for our skin, right? Higher dose Vitamin-A is great for skin that’s why they use uhm- Accutane which is- is a Vitamin-A analog to shrink the oil cells on the skin, also great for our eyes. Vitamin-D obviously great for our immune system, we make it too from the sun. Vitamin-E is great for our heart, it’s a natural antioxidizing, great for inflammation. Vitamin-K is really good is found in butter fat. It helps get calcium into our bone, right? Vitamin-K2, consider activated- a- activated X by western price, really important nutrients. So, these fat-soluble vitamins, we really need good gallbladder function to absorb them.

Evan Brand: Yeah, and if you don’t have a gallbladder, we’ll get into that in a minute, you know, I was just looking up, uh- reading the bile, the surgeries that people get. When you get into the gallbladder world, gallbladder surgery is just such a huge, huge money maker and it’s done often times in cases where it didn’t have to be done. And I told you we need to get a lady on whose uh, got a specific website about protocols for people with gallstones to try to help give them relief and to save their gallbladder. But another surgery which is crazy to me is called fundo- fundoplication, and it’s what they do to relieve chronic acid reflux. The surgeon tries to recreate your lower esophageal sphincter, by taking the upper portion of your stomach and wrapping it around the lower part of your esophagus and sewing it into place.

Dr. Justin Marchegiani: Wow.

Evan Brand: That just seems insane to me, they call it anti reflux surgery. How many of those people, just have H-Pylori infections that were put on acid blockers, therefore that LAS, that lower esophageal sphincter wasn’t working properly, or maybe they had a mineral deficient or maybe it was a ___[09:18] issue and structurally, that could get adjusted, but instead, they go get their stomach wrapped around their esophagus and sewing together. That’s insane!

Dr. Justin Marchegiani: It really is, and that’s kinda what conventional medicine does. They can go to some extremes to fix things that in my opinion are much more foundational and much more simple. And most of the time I would say 99% of the time, the surgeries aren’t root cause, right?

Evan Brand: Yeah.

Dr. Justin Marchegiani: So if we look at the conventional side, we have things like a HIDA scan which is like a nuclear image, they swallow s- solution that’s nuclear, and uhm- they kind see kind of biliary function, right? You want typically a 33 to 40 percent kind of dejection fraction that’s normal, on the gallbladder. So, you can look at that with the HIDA scan, you can even look at, an ultrasound, uhm, to give you a window of the inflammation in the gallbladder. It’s not gonna give you how much uh, bile is flowing to the duct but at least give you- okay it- it- is there- is it stagnant, or just stuffed in there, is it inflamed. You can kind of get that sense as well. A lot of times they’ll do some conventional testing, ’cause if your gallbladder is inflamed, and there’s an immune response, you may see white blood cells uh- on the higher side, right? Uhm, you may also see certain liver enzymes, ALT is a common liver enzyme, AST is another enzyme that can be effective in the skeletal muscle, you can see GGT, think of the “G” in gallbladder, GGT is a big gallbladder enzyme. Bilirubin is a byproduct of red blood cell metabolism that comes out in the gallbladder. With high bilirubin, we may have some- some backed up gallbladder bile issues. And then a- also, I think alkaline phosphatase is another big one that we may see on the higher side. So, we’re gonna see bilirubin on the higher side, alkaline phosphatase on the higher side, and then we’re also gonna see potential HIDA scan issues, that can- those are- HIDA scans more like pathological.

Evan Brand: Yep.

Dr. Justin Marchegiani: There are a lot of people that are in between that may be okay on the ultrasound or maybe okay on the HIDA scan and we can use some of this functional test as well. Uhm, but really important we gotta dig to the root, underlying issue on what’s going on there. And again, AST is more skeletal muscle but there’s some crossover with the liver, ALT is more liver. Think of the “L” in ALT as liver and then the alkaline phosphatate is a big gallbladder one, also a big one for zinc. Alanine transferase or ALT, asphotate transferase, and then alkaline phosphatase for ALP.

Evan Brand: Well, the good thing is, a lot of the blood markers you just mentioned are pretty standard. So, even if you’re not working with the functional medicine practitioner like one of us, you may be able to get your doctor to just run these labs, refer back to this podcast and look and see if you have an elevation. Now, the only problem is, the conventional reference range for blood testing is very bad. So, you may be quote, “normal” by your doctored standards but our reference ranges maybe tighter. So if we start to seal your ALT or your AST enzymes go up, it may not be up enough to flagged. So, that’s why it takes a trained eye to look at these numbers and see, and we’ve seen it time and time again, we get somebody on gallbladder supplements their AST and ALT go down. So, it’s amazing to see, we gave this nutrient, “boom” look at the blood changing just based on this nutrients, it’s really cool. Let’s talk about symptoms now, I think we’ve given a good-

Dr. Justin Marchegiani: Yeah, just to highlight one thing, you just wanna get that CBC done at- which is a complete blood count, and then also a CMP – Comprehensive Metabloc Panel profile, and it’s important, you need to work with a good functional doc because you may be okay in a lot of these areas and you still may have issues, so now what, right? So you don’t wanna just rule it out ’cause some of these testing are good, you wanna look at subjective symptoms, connected to the anatomy, connected to how your stools look, right? If we have fatty stools, blond stools, excessive amount of wipes to clean out your- you know, to clean yourself after going number 2 or just, you get skin marks on the toilet seat, we’re probably not breaking down fat. And again, if you have too much MCT oil in the morning, that can also do a tube instead as a laxative effect. So, you gotta look at it the trend in general, clinical symptoms, subjective symptoms, and then lab symptoms to really make a complete picture of what’s going on.

Evan Brand: That’s a good point ’cause my AST and my ALT on my blood looked perfectly fine. But when I had parasite infections, I had that low right side pain under my rib cage where my gallbladder and liver are. Your gallbladder is kinda tucked in with your liver under there, so if you look down at yourself on your right side up where that rib cage, if you’re having pain there, when I had parasites, I had ton of pain there, my blood looked perfectly fine. So I don’t want, like you said, you don’t wanna give a- a false sense of hope just ’cause your blood looks okay. There may be other functional problems that you’ll find by looking at stool testing for example. But let’s hit- let’s hit-

Dr. Justin Marchegiani: Yes.

Evan Brand: -on these symptoms, because you mentioned some but we needed just go through symptoms here and tell people, “okay, what would you be experiencing?”.

Dr. Justin Marchegiani: Mm-hmm.

Evan Brand: So, you mentioned, fatty, greasy stools-

Dr. Justin Marchegiani: Mm-hmm.

Evan Brand: You mentioned it takes a lot of wipes to clean your butt, you mentioned the skid marks in the toilet which if everybody is going on a high-fed diet these days, sure, that may be okay but if you’ve got gallbladder problems to start and then you try to go on to ketogenic diet and you don’t feel well or you don’t lose weight and you’re complaining to your doctor, that may be the part of the problem is gallbladder.

Dr. Justin Marchegiani: 100%. Also, autoimmune issues can affect the gallbladder as well. Gluten’s a big one, it creates those condition called primary biliary- what’s that last?

Evan Brand: I think you call it cholangitis.

Dr. Justin Marchegiani: Yeah, primary biliary cholangitis. I mean, typically just “PBC” for short. But basically you can have some scla- scarring of this uhm- on the- the kind of biliary tubes that go out of the gallbladder, and as well as the- you know, the gut- the liver goes to the gallbladder, the gallbladder kind of comes out together with the pancreas and comes out the sphincter of oddi, or the hepato biliary kind of ampulla, and that- that can kind of scar and it can sclerose, it can kind of have uhm narrowing of the- of that vasculature. Of course, it can back up, and if that backs up, and those enzymes can’t get out you can have pancreatitis as well. But that’s an autoimmune condition where your body is attacking a lot of that tubing that goes up to the gallbladder and maybe even can help with the pancreas, and that can narrow and prevent a lot of that stuff from coming out. So of course, gluten is a big component because that can really activate a lot of au- autoimmunity and you can also have a leaky gut, you can also have a leaky gallbladder which does aggravates more autoimmune attack because things that shouldn’t be out in the bloodstream are out and that exacerbates the immune system going after it.

Evan Brand: Yeah, so let me just read a few sentences on these whole PBC thing ’cause I think this is critical. We know, even just this is just standard you know, medical textbook stuff that says “it’s the most common among women”. And we know that Hashimoto’s is more common in women and men. So it says here, “the cause is not clear but we know it’s more common in people with…” guess what, “…hashimoto’s thyroiditis”.

Dr. Justin Marchegiani: Yes.

Evan Brand: So, it says here, “An autoimmune cause is- is thought possible because more than 95% of people with PBC have certain abnormal antibodies in their blood. These antibodies attack mitochondria. What triggers these attack is unknown…”, of course they say that but it may be exposure to a virus or toxic substance A.K.A. ‘gluten’, maybe dairy, I mean, you and I talk so much auto about- about autoimmunity so I’m glad that your brought this up because, you know, these people may have these symptoms, and they’re not gonna know what’s autoimmune in nature, they may just get the- the knife and say, “Hey, we’ve gotta pull this gallbladder out”. Not necessarily, what if we can shut down this autoimmune attack?

Dr. Justin Marchegiani: 100%. Also, here’s the bigger issue too. Okay, great, the gallbladder is removed, your digestion is now forever altered. I’ve yet to meet a conventional patient of a gallbladder procedure, whether surgeons that “oh, by the way, you’re gonna have to add in HCl, pro- or- lipolytic enzymes and bile salts for the rest of your life”. I’ve never really heard that, at least bile salts seem to be added in. I would say HCl and enzymes too, but I’ve never heard someone do that. Now, your digestion is forever altered, do you think there’s a connection with now you’re not being to breakdown cholesterol optimally ’cause that’s gonna be in the bile, right? The bile is 97% water, then you have some cholesterol, and cholesterol salts as well, and you also have some toxins coming out, that’s why if you have uhm- poor, you know, gallbladder-emptying, then you’re not getting rid of potential toxins that are in there too. So, we gotta be emptying that gallbladder. If we’re not breaking down Vitamin A, D, E, and K, if we’re not breaking down our fat-soluble vitamins, which I just mentioned, if we’re not breaking down cholesterol which is the building block for all of our hormones, do you think we’re gonna have problems ladies, uh- as you get into your 40’s and 50’s, with menopausal issues, perimenopausal issues, PMS, and we know the main connection, it’s kind of a slang but, I’ve heard many uhm- let’s just say general surgeons say it, it’s the 3 ‘F’s’ of gallbladder issues: fat, female and forty. And that’s the time to- late 40’s, early 50’s where hormonal transitions happen, and if you can’t breakdown those nutrients, you are setup for a menopause uh- of “hell”, so to speak.

Evan Brand: Yeah, in terms of side-effects, possible side effects of gallbladder remover- removal, it could be anything from pancreatitis, to increased risk of choline cancer to increased digestive sy- symptoms like heartburn, could be constipation. So, we’ve seen people that- they don’t feel well, after they get the gallbladder removed. And uh, like you said, there’s no surgeon out there saying, “Hey, I’m gonna put you on this comprehensive digestive support protocol, after we remove it”, no, they’re gonna you out with anesthesia, cut that bad boy out, and send you home in a day or 2. Uh, there’s a- a whole lists symptoms here I’m looking at now, symptoms of- uh- symptoms after gallbladder removal. I’ve had women have gallbladder attacks, but they don’t have a gallbladder. You know, it’s like, “well, how the heck does that happen?”. So, you know, the- the- the removal is not the “cure all”. Anything from nausea to gas and bloating, distension, burping, belching, feelings of fullness, heartburn, barrett esophagus, diarrhea, dumping syndrome, weight gain. There’s a whole article here all about post gallbladder removal weight gain happening.

Dr. Justin Marchegiani: And part of the reason why women get targeted so much – I hate to say it – is the estrogen. The estrogen kind of makes things sluggish and slow, it kinda takes- it kinda makes it turn into molasses. So, things really are very sluggish, very viscous, and of course, that can affect gallbladder and bile flow. Women that are on, you know, uh, birth control pills, that’s gonna- in- obviously increase estrogen levels, obviously just being stressed, right? You’re gonna take your progesterone, you’re gonna shoot it downstream to cortisol, and that’s gonna basically cause estrogen dominance there because you’re already starting to lower progesterone in relationship to estrogen. You’re getting estrogen in the environment from the conventional meat products, uh, water, plastics, chemicals, hormones in the meats as well, and then you’re also gonna be just getting it, just from uhm- being a woman, having 10 times more estrogen than a man. So, you’re- you’re already predisposed, and then when you add stress to it, it’s going to exacerbate it uh, big times. So, you really wanna make sure that you’re fixing the- like if you’re having- if you know you have a gallbladder issue, you also need to be going after the- the hormonal issues as well. And then we can dive deeper into the food allergies stuff too, so you gotta go after the hormones, gotta make sure you fixed the estrogen dominance, you gotta make sure you fix the digestive aspects, and then we can go into foods later.

Evan Brand: Well, I’m sure there’s gonna be a ton of people that are just yelling at us right now through they’re podcast app or YouTube or wherever they’re listening to us, and they’re saying, “Well, this is not fair, I already have my gallbladder removed, so what the heck do I do now?”. So, do you wanna address that now or should we talk about that later?

Dr. Justin Marchegiani: Yeah, so, off the bat, the underlying mechanism that was driving that inflammation in the body’s still there. Just the end target, the end uh manifestation of it is removed, but now other tissues may start to, uh, have issues, then also if you don’t fix the underlying uhm, digestive im- impediment which is, your fat-soluble vitamins, your cholesterol, your hormone building blocks are now gonna be thwarted in their digestive processes. So, you have to fix that to prevent compounding hormonal issues, 10, 20, 30 years later, number 1. Uhm, and then so obviously this- so- err- if you’re- if you still have your gallbladder, we wanna keep it by doing a lot of the preventative things. But on the food side, I outlined this in a couple of my gallbladder videos are down in the past. But there’s some common foods that are even uhm- let’s just say paleo-approved, but should probably be looked at- look at removing. So, of course we have the refined sugar in the guts. That’s kind of a no-brainer right here. But, uhm, in order of kind of like uhm, the most likely offender are gonna be eggs.

Evan Brand: Yes.

Dr. Justin Marchegiani: So definitely autoimmune template, cut out the eggs, pork, onions, chicken turkey, milk, coffee, corns, beans, nuts, apples, tomatoes, peas, cabbage, spices, peanuts, fish, rye. I’m gonna link my article that goes into this. So, everyone’s probably like, “Say it again!”, no, I’ll put the link below, don’t worry, take a look at the article, alright? But, I have them in most likely to offend to least. So, if you’re overwhelmed after hearing that like, “What the hell am I gonna eat?”. Just start with the biggest 3 or 5, or look at that list and say, “What are the biggest 3 or 5 that I eat on a daily or weekly basis” and just pull that out. Once we get the inflammation under control, we support HCl, we support enzymes, we support bile salt production, we look at the gut ’cause sometimes there can be infections like H-Pylori and giardia, and of course SIBO in and around that ___[22:31] that can exacerbate everything too. So, we get the infections clear, if we get the acidity and the enzymes dialed in, if we cut out some of the common offending foods, we may be able to start adding some of these foods in overtime. But I find pork’s a big one, eggs are a big one, those are like my- my 2 biggest right there off the bat, and they’re kind of paleo-friendly too.

Evan Brand: Yeah, eggs are huge and people over-eat them and, if you have gallbladder issues, uh- when I interviewed Ann Louise Gittleman, she said the same thing, she said eggs are the biggest offender. I’m like, “Wow, I thought that was just me”, no, it’s- it’s a real thing, and then also onion. I think she said onion are ready-

Dr. Justin Marchegiani: Yes.

Evan Brand: But that was- that was a problem for me when I  had parasites and I would try to do like stir or fry and throw some onion in there, I’d end up with that lower right side stomach pain, I’m like, “What the heck is it”, or if it was I had parasite infections but, the other- the other part of it was the onion. So, yeah, I at least temporarily, like you said going on an autoimmune protocol while you’re working with your practitioner to fix the other underlying causes, you’re gonna be in good shape if you do that.

Dr. Justin Marchegiani: Onions are also a ___[23:28] too. So there could be some underlying SIBO or small intestinal bacterial overgrowth going on as well. So, you gotta look deeper at everything. So, kinda like piggy-backing everything, alright? Women are gonna be the- more bigger offenders ’cause of the hormones, because of the- you know, the pregnancy prevention with the birth-control pill, so you have that, right? So we gotta fix the hormones, fix the hormones, number 2, cut out the foods, at least paleo to autoimmune paleo with those additional 3 to 5 to 8 foods I just mentioned. Get enzymes dialed in, get acids dialed in, and definitely bile salts added in, and if you already had your gallbladder removed, definitely do all 3, and those that up and watch your stools and make sure your stools go floating to sinking, right? Oil and water mix, so if you had the stool, with the whole bunch of undigested fat, and oil and water mix, the stools stay on top of the water, they don’t sink. So, you wanna see the stools sink, and ideally you wanna be able to clean yourself, you know, 3 to 5 wipes on average, and you wanna make sure when you flush, you’re not seeing big skid marks all the time. If you’re doing some MCT oil in your coffee there may be some issues there, too much of that can cause some undigested MCT, so be mindful of that. So, foods, acid, enzyme, bile salts, get the infections cleared, and if you’re a woman, get the estrogen dominance fixed, get the hormones balanced.

Evan Brand: Yup, and, how can you do that from a testing perspective, we mentioned the blood, but I’ll just throw a few other components of this in. Number 1 is the stool test, so we’re always gonna be running a PCR stool panel, or gonna be looking for all this. As you mentioned, we’re gonna look at H-Pylori, we’re gonna look for giardia, we’re gonna look for cryptosporidium, blastocystis hominis, there’s a ton of different bugs, there’s worms, there’s parasites, there’s bacterial overgrowth we look at, there’s candida that we look at, that’s all done with the combination of  stool and urine testing. And on the stool, there’s a couple markers that we can track, obviously, you looking in the toilet is gonna be the best way to track. Well, we like numbers, you know, Justin and I like data. So, when we look at steatocrit, which is a fecal fat marker that usually is expressed as a percentage. I like to see it, you know, 10% or below, we’ll see some clients, they’re 30, 35, 40 percent steatocrit, that means they’re not digesting their fats at all, and they while I’m doing a ketogenic diet and I feel like crap, it’s ’cause they’re not digesting anything.

Dr. Justin Marchegiani: That’s it.

Evan Brand: So, we gotta get that steatocrit down, and how you do that, well, one, clear the bugs too, supplement, and then, what was the other part of my brain? The blood, we talked about the blood, we talked about the stool, oh, the beta glucuronidase. So, beta glucuronidase at enzyme on the stool test we look at, that enzyme gets messed up due to bacterial overgrowth. When we see the enzyme is high, that’s when the estrogen dominance probably becomes more problem- problematic because now, they’re re-circulating the hormones. So, we do some like a calcium d-glucarate or a DIM, or something else, maybe a broccoli seed extract to try to get, or could be probiotics, could just be clearing bugs, taking care of the SIBO, the glucuronidase goes back down, and now all these quote, “estrogen-dominance symptoms” just disappear, and it’s really fun to see that.

Dr. Justin Marchegiani: 100%. So, kinda highlighting the test again, look at your symptoms, if you have pain in the upper right quadrant, under the rib cage, if you have problems breaking down fat, if you’re seeing a lot of your fat, your stool sinking or floating on top, not sinking. If we run a ho- comprehensive stool test and we see a lot of uhm, steatocrit, undigested stool, we see that greater than 10 or 15, whatever that lab marker is right in that area, we got problems, and then we gotta dig in deeper, and this could be the reason why you have hormonal issues too so we have to highlight that. Is there anything else in this topic Evan that you wanna go into that we haven’t gone in deep enough?

Evan Brand: I don’t think so, I would just tell people that if you feel discouraged, or, you know, you’re facing surgical removal of your gallbladder, I’m not saying the gallbladder can always be saved. I have a friend of mine, she’s in her late 50’s, maybe early 60’s at this point, and she was having major, major gallbladder pain, and I told her about taking digestive enzymes, but the pain just continue to grow. So, you know, I said hey, you might have to, you know, go to a doctor and get this checked out. This is very recent, so she did. And her gallbladder function was basically nothing, and she went in and she had to get surgical removal and because of with so much inflamed tissue around her gallbladder they couldn’t do the- the- the uh, laparoscopy, where they just give you a small- a small uh surgical side, they had to really cut her open like 6 to 8 inches, they hadn’t take out the gallbladder, and the surgeon told her, that her gallbladder was so heavy, full of stones that it felt like a concrete block. He said there was no way you were gonna save this gallbladder. So, I think there is a point of no return, where surgical removal does happen, we’re not shaming anybody or making fun of anybody if you got your gallbladder removed, that sucks, like she had to get it out, there was no turning back. And now, you know, she’s got tubes coming out of her stomach to drain her bile until she recovers from the surgery. So, obviously, that’s an extreme case but man, uh, you know, it can- it can get to a point where surgery is the only option but we’re just trying to help you before you get to that point.

Dr. Justin Marchegiani: Yeah, so if we don’t have enough, if you don’t eat good fats, then we don’t have good gallbladder flow, then, what happens is, it’s like not changing the oil. A lot of that bile uhm, and that cholesterol can crystalize. And then overtime those crystals can- can produce more and more crystals. And then imagine these little crystals that are like- a little mini or- miniature-like porcupines. And imagine that gallbladder contracting, it’s like giving a- a big porcupine a nice hug, right? Probably not the best thing. So, that can create a lot of inflammation, and the more little porcupine you’re having your gallbladder, the bigger issue every time you have fat that contracts. And then also, we can have potential pancreatitis because of it ’cause those gallstones can eventually produce, can block the bile flow, and that can stop pancreatic enzymes from flowing into the small intestines. So, that can create more inflammation. So, the more this thing, err- there’s more of this issue, the underlying cause goes unaddressed, the more the inflammation accumulates, accumulates, accumulates, accumulates, there may be a drastic solution of cutting out the gallbladder. Now, I would say, the vast majority of the time, it can be saved. We have to make the food changes, uhm, we also do a lot of gallbladder bile support, we’ll also use things like phosphatidylcholine, we’ll do beet root powder, we’ll do taurine, we’ll do dandelion, we’ll do artichoke, French trees, or herbs that’re designed to help to help one thin out bile flow, they can smooth out the little crystals, so imagine like kinda coming in there and smoothing out all the little porcupine barbs. Uh, that way they aren’t as sharp, and then we can be very careful with our fat consumption, maybe we do the tiniest amount possible. A lot of the coconut fats are easier to process and digest. So, maybe we’ll do more coconut fat, we’ll just do- just the- the largest amount of fat we can handle without issues, we up the enzymes, we up the bile salts, and then we give a lot of those herbs to smooth out the bile flow, thin out the bile, and smooth down the crystals. We’ll even do some- some like extra phosphorus drops to even thin out the bile uhm stones as well.

Evan Brand: Yeah, I do beet powder every day. You know, part of that for my circulation issues dues to all the mold in my body, so- so the beet powder’s been really helping. But, you know, back to my friend, you know, she was, she’s a woman, she’s over age 40, she does have excess weight, you know, she is overweight, she is very sedentary, uh, she did have some familiar health issues as well, you know, any- any family history of uhm- diabetes, other type issues like that can- can increase the risk of gallstones which then increase the risk of these problems, so, if you were to take all of the things you don’t wanna be sedentary, you know, overweight, uh, etc., poor diet, she had all those things against her. So, I’m not gonna- I’m not saying that everyone’s gonna end up like that with her case which is extreme but, you know, I just wanted to point out, hey, sometimes there may need to be a surgical removal. But, we just- we wanna try to prevent that. Statistics I found say there is about uh- 3 quarters of a million surgeries every year for gallbladders.

Dr. Justin Marchegiani: Exactly. Then we kinda talked about, our women- right- our- our fat, 40 and female. The big issue is, estrogen is a big uhm cause of kind of making the- the gall uhm, making the bile more sludgy, so is insulin. So, insulin is also another stimulating factor, this is part about I think where the fat comes in there, because the more weight you have typically is more insulin-resistance, insulin’s that hormone that sticks sugar into the cell, converts it to fat, so if you have more insulin, that’s a greater likelihood of making the bile flow more sludgy. So, if you have high levels of insulin, that’s gonna slow up the bile flow, and then if we have uhm, high levels of estrogen or just estrogen dominance, that’s gonna sludge up the bile flow as well.

Evan Brand: Yup. I’m sure we could keep going on this topic all day but, we should probably wrap it up. Reach out if you do need help, you can go to, and Justin’s summit is coming up very-very darn soon. So, I don’t know when you’re listening to this, if you listen to it in the future, and you already missed out, well, you can purchase his summit, but if you’re listening to it ahead of time, his summit is going live very soon, in two weeks at the first week of March. So, go to Go register for Justin’s event, it’s gonna be awesome, I interviewed him, which I thought was probably one of the best interviews possible, and interviewed me, and I talked about some other stuff that he hadn’t talked about. So make sure-

Dr. Justin Marchegiani: [Crosstalk] …interviews too.

Evan Brand: Thank you, thank you [crosstalk].

Dr. Justin Marchegiani: …for sure.

Evan Brand: So, so go register, uh, it’s- it’s gonna be probably one of the biggest events of the year called Thyroid Reset Summit. So,, go check it out and to run through health talks which is like the apple of summits, they do a great job of putting things on, and there’s, I don’t know what, 30 other experts on there. So-

Dr. Justin Marchegiani: 30 great experts. And also, I’m giving way the first uh- 3 to 4 chapters of my new book coming out, the thyroid reset. That book will be coming out in the next uh, few months here, so, get your free intro copy and then I really appreciate you guys picking up the book as well. Get me up there on the Amazon ranking so we can help more people, I appreciate it. And also, just to finish with this uh, article, here, the uhm conclusion, very important here for gallbladder issues, just to tight home, repeat yourselves a lot because repetitions some other skill, here’s the conclusion, insulin resistance is a risk factor for the incidence of gallbladder sludge and stones during pregnancy and after. And then it says insulin resistance may represent a causal link between obesity, overweight and gallstones. So our big mechanisms here, just kind of- f- coming in full summaries, if you missed the whole entire podcast, if you get this one thing, you got it. High levels of insulin, increased gallbladder sludge. High levels of estrogen, or estrogen-dominance, increased gallbladder sludge. Inflammatory foods, right, that drive insulin and inflammatory foods that are paleo friendly like, pork, like onions, like eggs, like coffee, maybe an issue, and then of course the low HCl levels, uhm, the low-fat diet, uh, all of those things and eating in the stressed out environment, those are gonna be your big 3 or 4, then also infections, giardia, gluten-sensitivity, SIBO, all of those things are gonna drive, probably the big 5 factors. Infections, insulin, estrogen dominance, low HCl enzymes, and then hidden food allergens. Those are your big 5 factors of this gallbladder issue here.

Evan Brand: Yeah, well said. And I love my friend to death but my wife and I were driving in the parking lot the other day, and she’s- and- and then we see our friend who just got her gallbladder taken out, and she’s sitting in the Taco Bell Drive Thru, and I’m just like, “No, that’s exactly what got you in this problem in the first place”. So, the diet is so critical, you can’t skip it.

Dr. Justin Marchegiani: Hundred percent, excellent. And for anyone enjoying this, I’m gonna do another live Q&A here tonight, this at- you know, the very end of the day, probably around 5, 6 o’clock here central time. Make sure you subscribe to the YouTube channel, we do a lot of live Q&A. So, go to If you’re listening to the channel now, make sure you hit that bell, that gives you the notification. So, if you’re on your phone, it’ll pop-up as it ___[35:35] doing a live chat. Even if you’re not around for it, just your little- little question in. So, we do a live Q&A, it’s op-in question, if there’s a topic, keep your question to that topic, if it’s a podcast, we may or may not get to questions ’cause we kinda get in our flow state and uhm, we may just be really focused on our conversation.

Evan Brand: Take care.

Dr. Justin Marchegiani: Hey Evan, you have a good one, take care.

Evan Brand: You too, bye.

Dr. Justin Marchegiani: Bye everyone.




Peri-Menopause and Female Hormone Balance Solutions | Podcast #213

Peri-menopause can be hard on some women. It brings fatigue, mood swings and sleep troubles, a stressful transition that can last for months or years before menopause.

In today’s podcast, Dr. Justin Marchegiani explains the process of peri-menopausal stage and its effect to the body. Learn how the lowering levels of progesterone make one’s system more estrogen-dominant, the different issues brought by peri-menopause especially stress, mood issues, hot flashes, depression. Also, learn how to minimize its effect. Continue for more and don’t forget to share. Sharing is caring!

Dr. Justin Marchegiani

In this episode, we cover:

02:26    Adrenal Gland

04:31    Female Hormone Cycle

07:31    Hormone Physiology 101

26:27    Stress Response Buffering

12:35    Effects of Estrogen Exposure to Men


Dr. Justin Marchegiani: Hey guys! It’s Dr. Justin Marchegiani, welcome to today’s podcast. Uh, congratulations to Tom Brady and the New England Patriots, great go- not really a great game on the offensive side, great defensive game. Uh, 6 superbowl victory for Tom. And I did a podcast on Tom’s performance secrets 2 weeks ago which become even more pertinent today based off of his victory. He is officially the go- greatest of all time. So, really good uhm- to go back and revisit that podcast, lots of good insights in regards to sleep, in regard to hydration, in regards to nutrition, reducing inflammation, uh various training techniques, all these things I think are, a conglomerate of tools that uh- Tom uses to improve his performance, heal fast and keep his uh, pliability and performance up the uh- at the, you know, at the highest age possible. Really, to be a successful quarterback in the NFL, it’s pretty amazing.

So, today, we’re gonna open it up here for uhm… here, I kinda like- maybe a little live podcast here. Anyone wants to chime-in in these specific topics they want me to go into today, we can just choose a topic and just go off the cup and go live. I’m on Facebook as well so, feel free and check in with me on any of these mediums here so far. I’m gonna dive in one topic here today. We’ll go in on peri-menopause. So peri-menopause is really interesting. This is the kind of the phenomenon where you’re in this transition time of going into full menopause or- typically peri-menopause is just starting to miss some periods, you’re maybe in your mid- ty- typically upper 40s. Usually menopause starts between 48 to 51 and it can take 10 years, meaning the symptoms that you deal with during menopause, that can take up to 10 years sometimes. The hot flashes, the mood issues, the depression, uh anxiety, uhm those type of sleep issues, scrappy skin, all those things can kind of con- you know, consolidate and happen over a long period of time. Typically, peri-menopause is that- one year. Once you get in the menopause- menopause typically is like, once you’re been no cycle for 12 months. So, peri-menopause is this in-between time  where skipping cycles, maybe you have a period every 4 months, or 6 months, or you’re kinda lost your cycle regularity, you know, fertility may not quite be there, you may not be ovulating as much- uhm- you start to see your cycles just getting more and more irregular, typically in you’d mid- typically upper 40s when that starts to happen.

Now, what do we do about that? So, first thing is, make sure you’re not getting exposed to toxic hormones in your foods or in the environment. That’s number 1. Uh, number 2, the biggest hijacker of your hormones is gonna be your stress hormones, A.K.A. cortisol and adrenaline. So it’s really important that you get your adrenals looked at if you’re worried about peri-menopause because, DHEA Sulfate, this is the major sex hormone precursor that’s made by your adrenal glands. This is actually coming from your adrenals and it’s a precursor to make more estriol in women. It can go more testosterone in men. But estriol is that predominant estrogen that you’re gonna have when you start becoming more menopausal. Typically when you’re cycling and fertile, it’s more estradiol, E-2, the “di” is kinda- right, 2. And then estriol, or the TRI, that prefix for 3. So you start to make more estriol, and that’s gonna be more anticancer. It’s gonna be- it’s have some really good anti-aging benefits. Estriol’s really important for hydration, that’s why low estriol- low estriol can- can create vaginal dryness. It’s also a really good anti-inflammatory, it really helps with brain inflammation. This is why a lot of mood issues and brain fog and cognitive issues start as you become more and more uhm- peri-menopausal into menopause.

So we have to look at the adrenal glands, that’s number 1. Because these adrenals make DHEA, also cortisol hijacks your hormones. Cortisol increases blood sugar, and also decreases protein synthesis, meaning, you have less protein going to build up your brain chemicals and build up your muscle tissue, and that protein is primarily running through gluconeogenesis where it’s shredding up that protein and making more glucose out of it. That’s what stressed us. People get more flabby, they get more cellulite because of cortisol. Breaks down connected tissue, and it breaks down amino acids. So, your- getting your adrenals looked at is really important.

Uh, number 2 is looking at your female hormones as many women as they go more into peri-menopause, they become more estrogen-dominant. And the reason why is, because we talked cortisol hijacking, your hormones- it does so, ’cause it pulls progesterone downstream to make your stress hormone. So this is important. The more stressed you get, the more you deplete progesterone, that puts you more into an estrogen-dominant state. Typically, we have more progesterone than estrogen. It’s about a 20 to 25 to 1 ratio progesterone to estrogen, and when you start going estrogen-dominant, people think, “Oh, that means estrogen goes higher”. No, it just means there’s ratio, it starts to drop. So you still may have more progesterone, there’s that ratio drops down a little bit, and you start to see estrogen creep up, but you may not see estrogen ever go above progesterone. Just keep that in the back of your mind. That’s gets commonly confused.

So we have the progesterone there. And typically, when cortisol’s prolonged, this also affects the HPA, H-P-A-T, H-P-A-T-G-G: hypothalamus, pituitary, thyroid, adrenal, gonadal, gut access. So it affects that feedback loop from the brain, and the hypothalamus and the pituitary ups- upstairs to that feedback loop of the glands secreting hormones downstairs. And this is important, so we start to see cortisol rhythm operations. The cortisol rhythm starts fluctuating. We start to see it in women with their cycle operations. A lot of times we just see a lot of PMS or the extreme PMS is PMDD, which is that week or so, before you actually menstruate or bleed. And then we also see a lot of- a lot of times, sometimes shorter cycles, going from 28 to 26 to 24 to 22. So we start to have a shorter luteal phase, just really important ’cause your luteal phase is that primary phase where you’re making more progesterone. So we do test while we actually look at progesterone every other day for a full cycle. And one of the things we’ll start to see is, your overall progesterone that you make throughout the whole month, typically should be above that 3000 marker so, it starts to drop. You start to see it drop. And that’s big, ’cause that’s kind of like looking at your overall progesterone sum, we start to see it drop, and a lot of times that can happen when you compress that luteal phase when you shorten it, ’cause you just have less days where you’re even making progesterone. Uhm, that’s a big one. So we start to see cycle aberrations there, we could see a shorter luteal phase, we could see a longer follicular phase, we may be out of sync, or we’re not ovulating at that right time and your ovulation could be totally off, or maybe you’re not even ovulating. ‘Cause, you know, to have that good ovulation to signal, we need a- [clears throat] a rise in estrogen followed by rise in progesterone and then estrogen kinda pitters out while progesterone stays high and drops. This is kind of our typical rhythm, and how women’s cycle work. So, just kinda first thing that happens, those gotta- kind of hormone physiology 101.

So, we start off by menstruating. That menstruation is typically signaled by a drop in progesterone and estrogen. First thing, progesterone and estrogen drop. That’s step 1. 2, menstruation happens after that, that’s the shedding of the uterine lining. We want brighter blood that’s more oxygenated, more fresh, for starting to see browner, thicker kind of clottier stuff, it just could be- uhm- the uterine lining from previous cycles that didn’t flush out. So, 1, drop in progesterone and estrogen, 2, menstruation, that’s gonna happen for a few days, anywhere between 3 to 7 days, okay? We don’t wanna go more than 3 to 4 tampons per day on average. For our average high, is if not we lose too much blood, we go hemorrhagic, we go anemic because of that. Step 2 is FSH starts to increase. FSH is our brain hormone, follicle stimulating hormone. That FSH start to make the follicle grow a little bit. That follicle starts to produce estrogen. Estrogen starts to rise, right? As estrogen starts to rise, that starts to signal luteinizing hormone, which is our other brain hormone that talks to our ovaries. And then progesterone starts to rise typically around day 12 to 13 after that. So here we are at day 12 or 13, estrogen’s kinda topped out, that signals LH, then we have progesterone going up like this. So progesterone’s going up, and then at some point, estrogen starts to fall again, progesterone stays up, and then around day 28, they crash together and that signals the whole entire step again.

So, drop in estrogen progesterone, signals bleeding, FSH, increases, FSH creates more estrogen, more estrogen creates more LH, more LH creates progesterone, estrogen starts to drop, progesterone stays high, estrogen and progesterone drop and then signal bleeding at the end. So that’s kind of a general uhm, cycle physiology 101, Most people are clueless about that. When I talk to a woman, I say, “Hey how long is your cycle?”, the biggest kind of common misconception, “Oh, it’s 3 days or it’s 7 days”, like no, not your menstruation, your full cycle. Your cycle is from day 1, first day of bleeding to next day 1, typically 28 days later. Uhm- most people get that confused your cycles, your full hormonal rhythm, day 1 to day 1, how much you menstruate is gonna be your- your bleeding, your period time so to speak. Hope that helps. That’s a common misconception.

Alright, so we talked about adrenals, we talked about our female hormone cycle, we talked about hormones in the environment toxins. These things are really important because they disrupt, they put more stress on our metabolism to be our- to be our detoxification system to be able to metabolize hormones. Gut functions’ so important because this is where we absorb a lot of the nutrients from our food to make our hormones, right? Hormones are made from good cholesterol, right, it goes cholesterol pregnant alone and then 27 different hormones that spit out on the stress side, on the mineralocorticoid side and on- then on the anabolic estrogen progesterone, testosterone side. So we- we need to be able to absorb these nutrients so we can make our hormones. We need to be able to absorb nutrients to help buffer the stress response. Magnesium, L-Theanine, GABA, they help us buffer that stress response so we could- think of it as like, imagine buying a car where you can only shift it from first gear to second to third or fourth, fourth to fifth. So, all you can do is bring that car up from low to high but you can’t downshift. And a lot of people are in this place where they cannot downshift their metabolic car, so they constantly feel stressed, they cannot ever bring it down from fifth gear back to first gear. And this is one of the biggest issue- biggest issues we see, and if we can’t absorb our good amino acids, and- and- and make our good inhibitory nerves, transmitters like GABA, through L-Theanine, through magnesium, through dopamine through serotonin, we’re gonna have problems. And typically, this starts to mess up sleep. Starts to mess up our melatonin cortisol rhythm which is the next step. And that’s gonna be basically- melatonin goes up at night, cortisol goes down at night. We have this inverse relationship – melatonin up, cortisol down, right? We get this big “X”. And when cortisol stays high at night time, it disrupts sleep, it prevents melatonin from coming up. Melatonin is a powerful antioxidant, it’s powerful anti-cancer, it’s very anabolic, it helps you heal, recover, turn-over your neurotransmitter successfully and heal your body, ’cause you really tap into ’em, make a lot of your growth hormone in that first half of the night, 10:00PM to 2:00AM. So we wanna be asleep so we can plug in and access that growth hormone.

Okay, so we got our rhythm, cortisol, adrenals, digestion, absorption, and then also, the amino acids that we absorb through our digestive system, also help run our detoxification system. So, we wanna stop the toxins on one side, not drink out of plastics, not consume pesticides, consume organic, right, get, you know, higher quality step-4, step-5, if we’re using the whole food, step-method works, more grass-fed, pasture-fed, organic, the whole nine yards that’s gonna help us make more of the nutrients, absorb more of the nutrients where we can actually detoxify as well.

And then we talked about those hormones helping with sleep, helping to buffer stress. Uh, very-very important components to female hormone health, as well as make hormone health. Uhm- males really get the sure end of the stick, because there’s a lot of estrogens in the environment, you don’t have a lot of synthetic androgens in the environment, so men really get clavier because when men get a whole bunch of estrogen exposure, it starts to inhibit LH. LH is that upstream hormone in the brain that talks to the gonads, right? With the uh- the cells lay dig in the testicles to make more estrogen… I’m sorry, to make more testosterone so that estrogen disrupts that signal. Now we don’t talk to our testicles to make more testosterones, it starts to inhibit that. And it’s a- it’s a really a vicious cycle. With women, they just become more estrogen dominant, which is a good, that starts to mug their cycle. With men, it starts to decrease testosterone. And you start to see things like gynecomastia – man boobs. Uhm, maybe guys even being overly emotional because they’re- it starts throwing off testosterone-estrogen balance as well. So that’s gonna affect their mood and- and focus on- on the male side as well. And of course for the woman, it- it causes same things, ’cause they can create more PMS which can create irritability, breast ___[13:48], back pain, moodiness, irritability, sleep issue, all those things that you know, women do not like. And men don’t like them either, of course. It’s a two-way cycle in that for sure.

So we think we hit all the major things. I’m gonna open it up to questions, primarily on the peri-menopause, female hormone side of the fence. And again, this is total live podcast here. Uhm- again, I just- I interject a lot of clinical information ’cause I work with patients in the trenches. So if you have any of these issues and you wanna dive in, click below to make sure you subscribe, hit the bell, and schedule a consult with me and my staff. Let’s see what kind of questions we have here off the bat. Try to keep it pertinent on the topic if you can.

Alright, let’s see here. Uh, “How bad- how can a bad gut affect hormone?”. So it’s going to affect the two-wa- oh, couple of ways. We absorb all of our nutrients to create our hormones to our gut. Number 2, we absorb the nutrients to our gut to help us detoxify – number 2. And then number 3, dysbiotic bacteria increases an enzyme called beta-glucuronidase. And beta-glucuronidase, uhm deconjugates estrogen. So we have an estrogen molecule right? It is floating in our bloodstream, we conjugate it, we bind it to a protein, to escort it out of the body. It’s kinda like, hey guys in the night club, whatever rock and rowdy, security guard comes up, like puts the guys hands behind his back and like escorts him, out of the club, right? That’s kind of, when you conjugate, think about as putting- err- handcuffs on that rowdy hormone. And de-conjugation is just someone coming around with a handcuff key, and uncuffing each person, right? Think- that’s what’s happening with dysbiotic bacteria… dysbiotic bacteria, bad bacterial overgrowth, increases beta-glucuronidase, then we have the- the handcuffs, are taken off the hormone, and they can be rowdy again. So those are the big 3 ways that can affect that.

Okay, excellent. Any other questions, feel free- uhm, feel free and chime in. I’m- I’m more than like- I’m more than willing to answer any more questions. Okay. I think we hit all the major things here. Try to think of anything else we can do. Pa-pa-pa-pa-pa, awesome… Tssssss… ‘Kay. “What’s a good mindset to have when you are feeling hard bowel, and of crohn’s flare up right now?” So, ob- obviously, gut issues can affect hormone health too, right? So question is, how did it happen? I want to feel like I’m in control of the vicious cycle. I wanna know what the heck happened. So, I wanna look back and at least gain control over how I gotten into this flare up. Maybe the first thing I wanna know. And the second thing is what actions are you gonna take to get out of that flare up? So, feel free and check video 2 to 3 weeks ago on how to, you know, reverse an autoimmune condition flare. Take a look at that video. I go over a lot of good steps that are needed to- to be addressed.

Uhm, “Is fatty liver curable? What supplements would you recommend to help?”. So, yeah, it is, I mean, it’s typically gonna be a combination of insulin resistance. And insulin resistance has a major effect on female hormones. How? Because high amounts of insulin, are going to up-regulate specific enzymes that can increase androgens in women. So that can really throw off androgens, and then of course high amounts of androgens can- can mess up proactive, and prolactin can screw up uhm, estrogen and progesterone, right? So, this is a really, you know, concerning thing. So, high fructose, corn syrup, insulin-resistance are gonna be the big things that are going to cause that.

Uhm, “Thoughts on IF in regaining cycles, avoiding IF until cycle returns”. So, uhm- typically, what I would recommend, is that you do not engage in any intermittent fasting until you get your hormones back and under control. Not eating food for a long periods of time can actually be a stressor on your hormones. ‘Cause we need nutrition to run our metabolic systems. But if you are more stressed, it- it may be too much stress on your body avoiding these foods, these nutrients. ‘Cause then, longer periods of time may cause your adrenals to make more cortisol, and adrenaline and gluconeogenesis to regulate your blood sugar. The more stressed you’re at, uhm- the more stressed you’re at, the better you’re going to absor- the more stressed you are, the more gluconeogenesis, the more you’re gonna rely in other hormones to pick up your blood sugar. If those hormonal systems are weaker, you’re essentially gonna need more of those other systems to pick it up. Now, by eating and stabilizing your blood sugar, that’s gonna take stress off those hormonal systems that are weaker, and give them the chance to get stronger. It’s kinda equivalent if you break your ankle. You walk around on crutches for a bit, the goal of walking around on crutches is going to be to take weight off your ankle so it can heal.

Alright, excellent. Very good. Uhm, “Can low progesterone in ladies cause low libido?” It definitely can. Low progesterone can definitely cause, uhm, low libido in ladies. Uh- lot of times it’s just the estrogen dominants that starts to pick up, that can be the big issue.

Uh, Samuel writes in “Hey doc, been drinking a little more alcohol recently due to football games and hunting season, seems to have messed up my circadian rhythm a bit. Uh- what would you recommend for a reset?”. Uhm, more than likely, I would just stop with the uhm- stop with the alcohol kind of down a bit. You could do more vitamin-C and more sulfur amino acids, uhm, to help your body heal.

Excellent. Uh, let’s see here. Any other questions? Barbara Scott writes in, “Could chronic muscle pain impart of the menopause phase of life?”. Well, yeah, I mean, it definitely could. I mean, it’s very possible that, uhm, your adrenals are weaker, and then that’s gonna help- that’s gonna impair your body’s ability to manage inflammation well. It’s very possible. Uh, a lot your hormones have really good anti-inflammatory fats-progesterone estrogen, it just depends on what the root cause is. Did it happen from food? Did it happen from… uhm- stress? Did it happen from poor sleep? So, I wanna get a- a window in what the heck is happening there as well.

Okay, excellent. Let me keep on rolling here. Uh, “Can a hair analysis tell you a lot of accurate info?” Uh, I think a hair analysis can potentially give you some good info, the problem is, it’s all downstream information because all those nutrients that get into your hair, the half that come in through the gut. So if you have impaired gut issues, that’s going to affect what’s in the hair. So if people are looking at the hair, they’re looking at all these different mineral ratios in the hair, but if we have a gut issue, I consider that to be a lot more upstream.

Uh, “What’s the best way to balance out estrogen and progesterone in ladies?”. So, off the bat, uhm- you gotta at what the underlying reason is. Is there toxicity issues, number 1? Is there uh, absorption issues in the gut, number 2? What’s your adrenal strength at, number 3? How is your hormonal rhythm, number 4? And then I also wanna look at just uhm, you know, exposure to conventional, uhm hormones in the food. Those are all gonna be big ones, they’re off the bat.

Ugh, let me just see if I can continue to do that. “Tom Brady’s a beast last night”, not in- actually, all I had during the game was one kombucha, during the game, I got some keto-cups which are like one gram of sugar, uh- coconut, like peanut butter cups but that uses coconut oil instead. And then I had a pizza which is a cauliflower crusted, and then I use the dial almond cheese. So that was the big one that I had there.

Uh, “What would you recommend to naturally treats- treat sinus-headaches brought on by cold?” So, if you go to my site, and look at recommended products,, and then you look at recommended products. I have a couple of links to amazon products that I like for that. I like either a combination of the nasaline or a sinus- just injector, and essentially uhm, the Xlear Sinus Rinse. I think that works really good. The NeilMeds, good but the Xlear has a lot of the xylitol in there, which is great at killing different kinds of bacteria and also flushing things out, and it’s really helpful with that post-nasal drip as well.

Uhm, I think we hit a lot of good things here. JACK ATTACK writes in, “How do you feel about citrus pectin?”. Well on the context of hormones and peri-menopause, it’s really good at binding up a lot of these metabolized hormones that may have a problem getting escorted out, and it kinda puts the handcuff back on these hormones to help it escort outside the- of the body. So I think it really helps with detoxification of hormones. Thanks Jack, appreciate it.

“I’m an active 30-year-old male on a paleo diet suffering from bloating, loose stools every morning, find myself wanting to eat more starchy vegetables for energy.” Yeah, so I mean, that’s kind of a broad statement, but in general, I would look at the gut and figure out what- uh, the next step is there because the gut needs to be addressed.

Okay, try to keep all questions related to the topic of peri-menopause. Uhm, that’d be super helpful for me so I know what’s going on. ‘Kay, very good… Anything else guys? What else is going on? “What cauliflower crust pizza did you do?”. It’s a local place by my house that- that does an organic cauliflower crusted pizza, I’m not sure the actual brand. Uhm, and I did the diet cheese. So it’s kinda  lower carb too which is nice, so, I don’t get all bunch of a carbs either, feel pretty good afterwards too which is nice.

Alright guys, hope everything’s going well. Make sure you guys subscribe over to my thyroid reset summit,, we’re going live in a month. We got a whole bunch of free stuff I’m giving out as well. I’m giving out the first like, 25% of my thyroid book. So, really excited for that get out. Hopefully it’ll provide a lot of great information. Everything I try to put out there s- I wanted to be action-oriented, so you guys can use it to actually start getting better. I help more people through my content than I actually do in person. Obviously, you know, having a personal relation, if you can’t substitute that, but this is a great way to get good information out to people here. So, make sure you sign up.

“Best lab to discern HA versus early menopause?”. Uhm, can you define what HA is? Uhm, much or- I mean, it’s probably something very common. I just- give me what that meaning is there…

Uhm, “What’s the difference between ox bile and bile used by conventional docs…”, uh- I think you mean “urso… “, uh- I’m not sure how you pronounce that – ursodeoxycholic acid. So typically, a lot of bile- ox-bile’s typically used as a bile salt supplementation when they take it from oxes or- I think bovine sources it sounds like, and they’re using that supplement as wise. Now, my line and Liver Supreme, we will use bile salts, we will use beet roots, we will use… uhm- french tree, or ___[24:47], things that are really supportive for the liver, supportive for the gallbladder, thinning out the bile, and then we’ll also help provide uhm- extra bile as well because if we can’t break down our fats, typically we’re gonna have a hard time breaking down our cholesterol, right? And if we can’t break down our cholesterol, that’s gonna really hurt our hormones. This is a really important question ’cause if you’re dealing with peri-menopause, this may significantly affect your hormones not being able to break down good quality fats.

Uhm, so- “Hypoth- hypothalamic- hypothalamic amenorrhea versus early menopause?”. Okay, so amenorrhea. So amenorrhea is like you’re still in that cycling age, it’s premature, you’re not having your period, okay? I have a woman who is 40 years old, uhm, this last couple months, started to get her period back. I see that happen many times, she wants to have a second child. Her period’s back for the first time in two years. Why does that happen? It’s a combination of typically poor gut issues, you’re typically under- you’re getting underneath nutrition, and it can be a combination that you’re not eating enough, or you’re not breaking down and absorbing enough. And then of course, all of the hormonal stress that compound for math, ’cause of course that creates adrenal issues, and that creates female hormone issues, and that detoxification issues ’cause if you don’t absorb, then you can’t run- put the nutrients in and run detoxification systems as well. Uh, so best labs to discern that, I mean, you wanna run a high-quality month-long test, and then also want to run some blood work and also some uhm- some adrenal testing as well. So you’d wanna dig in, find a good functional medicine doc to get that set up for ‘ya.

Oh, great to hear Irma, glad you’re registered, awesome. Uh, another great question just came in here. Try to keep it to the female hormones today guys… Uhm, “If I see anything remotely sad or happy tears, is that an estrogen issue? Will that affect gut health?” So, it’s hard to say, is this a- a guy you asking this question or female? Uhm, but, yeah, definitely, hormonal imbalances can affect the emotions. And you know, it’s gonna be- you’re gonna be looking for that change in emotions, maybe more emotional’s typically what you’re gonna see, but yeah, that can definitely have major effects on your emotions as well.

Nora writes in. Hey Nora, “Got acne around my jaw since June 2018. Last consult you asked if I had started doing anything different around that time but I didn’t recall. Later I found I re-introduced some thyroid support for hypothyroidism around that time. Since tests show no more hypothyroidism now, is it okay to stop the ‘Thyro balance’?”. Uhm, so in general Nora, we’d wanna make sure that we’re testing your hormones on the thyroid side, and as you’re dropping that down, we’d wanna make sure that your hormo- your TSH stays within a good functional range, as well as your hormones stand a functional range. So, it’s not something you’d wanna just drop out by itself, you’d- you’d wanna test you, and make sure as we drop it out, there could be, you know, that you’re doing good there. And then regarding any jaw acne that happens, I mean, we’d want to make sure number 1, insulin is okay, right? Insulin’s good. Uhm, ’cause if you’re doing too much insulin that’s gonna drive more androgens and then that’s gonna activate the sebaceous glands to make more oil, and that can cause the acnes. So we wanna make sure insulin’s good, wanna make sure detoxification’s really good. So- and for me to add in more sulfur amino acids and detoxifying support to run those systems, that’s good. Number 3, potentially various fibers to help bind up some of these junks so it gets or- escorted out your gut better, and then I would say number 3, if we’re still having issues you may wanna add in some prostate glanding support like black currant seed oil, and email my office if we- if we-  I don’t have your protocol up in here in front of me yet, so when patients ask me about questions here, I- I may be having some incomplete info to go off of, so if we haven’t added any black currant seed oil, we may wanna do that to help with the prosta gland and then some help with the jaw issue. And the next thing will be to- to retest your hormones with the DUTCH test to look at also how you’re metabolizing your estrogens to make sure that’s getting better. But don’t adjust anything until we chat.

Yeah, vitex is gonna be a great hormone- a great herbal support, A.K.A chastry, that’s gonna be really good at helping progesterone balancing for sure, really good.

Uh, “After getting through menopause does one need to stay on additional hormone help continually through life?”. It really depends. So what I recommend is get all your hormones symptoms under controlled, number 1. Test your hormones, make sure your adrenals and your female hormones are relatively good, uhm, from lab-testing standpoint based on your age. And then I recommend gently tapering down your hormones and see how well you do. See if you can keep your symptoms, your menopausal, se- was under control, sleeping good, your mood’s good, vaginal dryness is okay, brain fog’s good, and if you can maintain that benefit while dropping that bioidentical hormone support, that may be an option but Barbara, you’d have to deal with that at a consult, and continue to monitor that and keep that dial on going, but that’s a great question.

Okay, great. Uhm… just kinda kind of- come in here guys if I skip your question, don’t take it personal, tryna go to the questions that are most pertinent to this conversation. Zoe-Holistic writes in, “Would you be worried about a 54-year-old woman, still cycling and ovulating? Would you recommend supplementation as a- oestrogen is very high”. It just depends if you’re 54 and you’re still cycling and- and- the cy- cycle’s relatively stable and lengthen, PMS-wise, I wouldn’t too wor- I wouldn’t be too worried, I wanna know more about your parents and this is something that your sisters or- aunts- aunts, and/or mom or, you know, mom went through as well, our grandparents went through? I wanna know a little more about the history. And doing some testing, right- I think would also be good just to see where your levels are at, I think that’s a really good thing. I’ve- I typically more concerned Zoe with people, uhm, prematurely going into menopause, that’s my bigger concern, that’s the thing I’m seeing these days. But I think it’s always good to get tested.

“Is there a connection between hypoglycemia and adrenal fatigue?”, yes! Great- great question Olga. I see a lot of low-blood sugar symptoms’ really being a big stressor on the adrenals, and then that can create a lot of lower progesterone issues, creates a lot of stress. I definitely see that being a concern.

“What is the average acceptable age for menopause?”, typically 48 to 51-ish.

Ik O, “Best test for progesterone levels?”. I mean, you can run a typical progesterone blood test, you know, we like to be at least 10 to 15 on that, around day 20 of your cycle, right? Considering your cycle being like 26 to 30 days, and/or like a- a good high-quality DUTCH complete panel that we’ll run around day 19 to 22.

Nora, you’re totally welcome. So, email my office if you need that black currant seed oil, I’ll put you on 2 capsules of that twice a day if your skin is still having some issues. Two caps, twice a day and I have a couple recommended brands.

Jessica Lynn writes in, “Does liquid vitamin-C raise estrogen? I read studies say that there’s a connection”. I’m not sure that it would raise it. I will typically give vitamin-C in fiber to actually help with estrogen detoxification, so I don’t think it would raise it, maybe there’s some modulate- maybe there’s some modulation effects, or may help modulate it but I couldn’t imagine it actually raising it, like taking maybe uh, hormone would.

“My kidney pain by eating a honey, age 27, serious problem?”. Uhm, yeah that’s a good question, kinda little off-topic, but in general, I would be careful with the too much fructose.

“Will chaste tree help with progesterone?”. It will, it’s gonna help with LH, luteinizing hormone which is gonna help talk to your- your ovaries, and that kind of female hormone area to make more progesterone?

DesignLover writes in, “Took birth control pills for 1 year for adult acne, it worked. Now I’m 37 and it’s creeping back around the jaw line. Connection to sugar or more estrogen related? Or more cortisol? Also, hard time sleeping.” Now again, like birth control pills can help, even though you’re actually giving more estrogen with the birth control pill, it does kinda level out your hormones, so you’re not getting swings. So, I think a lot of the hormone swings can really be a big effect there so we can kind of level stuff off. But I also see, you know, birth control pills cause more issues. You can see melasma as well, which is the estrogen, kind of stimulates the melanocytes and more pigmentation, you can kind of get that pregnancy mask, while on the birth control pill, and someone that can actually make their acne worse. I’ve seen it on both sides. Is there connection to sugar and more estrogen-related, yeah, there’s definitely a big connection with sugar because sugar will actually increase more insulin. And insulin will create more ___[33:23], which will cause the bacteria to feed off of your skin and create more acne.

“My natural doctor put me on liquid vitamin-C and I’m having short cycle, 26-27 days with very light bleeding and prolonged bleeding”. Yeah, I would need more info, I’d wanna test your hormones, see where you’re at. A lot of my younger female patients will use herbs to help the signaling upstream from the brain to your ovaries and then we’ll also- a lot of times give a little bit of bio-organical progesterone, but we’ll give it in a specific cyclical augmentation fashion while we’ll taper it up and down. But we really wanna be specific in how we do that.

Amelia V writes in, ” If taking T3 you mentioned in past, needing it uh- multi-x-day due to half life. Why am I only- why am I only RX dosage for the AM?” Uhm, so, yeah, if you’re just taking T3, I don’t recommend only taking it in the AM, and like if you’re doing a Cytomel or liothyronine, you’re gonna be dropping off on your- uhm- on your T3 within 4 to 5 hours, so you definitely want to uh, not do it that way. In the thyroid re- reset summit, we had ___[34:26] on the uhm- summit talking about these exact things. So make sure you subscribe, make sure you subscribe.

Olga writes in, “Can longtime use of Mirena iud cause energy problems?”. Yeah, Mirena can cause a lot of side effects. Merina is a synthetic progesterone, and there’s an iud to secretes that. So, yeah, it can definitely- I mean, my biggest issue with that is it just kind of seeps in your bloodstream throughout the whole month at least with like, birth control pills, you kinda take a reminder session, you know a 6 to 7 day reminder where you kinda- drop out your hormones and then- and then that can cause bleeding where you kinda have this steady state of hormones with the Merina, which I think’s a little bit unnatural because you don’t have any drop at all. That’s concerning, so- I always recommend my female patients if they want- uhm- an iud to try the ParaGard which is a copper-iud that’s non-hormonal.

Uhm, “‘Can’t miss’ interview from the thyroid summit? What was your favorite interview?”. It’s a great one, I’d had a lot of a really good interview. It’s hard to say which one was the best. It really depends on the topic. ‘Cause we’re really connected the thyroid to the gut, thyroid to the emotions, thyroid to the adrenals, thyroid to fertility, thyroid to female hormones, thyroid to- even male hormones or gut inflammation, or gluten, or autoimmunidase. So those, you know, it- it was so many different areas, it’s really hard to say.

Paul writes in, “In menopause, how to stop hot flashes?”. Well, a lot of times, the hot flashes can be from a lot of these upstream hormones in the brain like FSH going really high. ‘Cause think of the ovaries, right? Your brain makes hormones that talks to the ovaries to make more hormone, more female hormone. So, as the brain- as the ovaries aren’t, you know, don’t have the follicles coming in, and we’re not making as much hormone, the brain is trying to rev up the volume that talk to the uhm, downstream glands. And that FSH as it goes higher can really increase vasodilation so, giving certain herbs can really help with the signaling and help kind of decrease the volume a little bit, modulate the volume, and then giving some bioidentical hormones can also help modulate the volume as well. ‘Cause the brain says, “Hey, I’m getting a little bit more hormone in there naturally, we can lower the volume as well”, and then we deal with the herbs to help with the receptor sites too. So there’s a couple different ways that we can do it. But that’s kinda one of the major philosophies regarding FSH, and regarding a lot of the hot flashes.

Uhm, ” Is Chaste Tree something you can take to see how you feel…?”, I mean, you really want to be working with the functional med doc on this. A lot of variables when it comes to that.

DesignLover , “Is there a connection to an imbalance of hormones in women who haven’t bore any children?”. Potentially, I mean, women that haven’t born- birthed children, they don’t have that progesterone increase that happens, uhm- throughout pregnancy, so that- you that- 8 or 9 months where progesterone goes up because of HCG, that goes up significantly higher. So that may- let’s just say, you have a greater chance just kind of being more an estrogen dominance, over your- your cycling fertility time-frame so to speak, where hormone, who is uhm- pregnant one, they’re not gonna be using up the follicles as much ’cause you’re not cycling when you’re pregnant and a lot of time during the breastfeeding process. So, you’re not going to cycle through your eggs as fast. And then number 2, you’re more overall an average having a higher input of progesterone, so that has some effects as well.

Uhm, Zoe writes in, “Do you find the people with more severe menopause symptoms always have more adrenal issues when testing, is that your finding?”. I wouldn’t say always but I- ’cause it’s- it’s-  I don’t- I’m not a big fan of absolutes but I would say yes. I would say on average, that is a significant correlation, more menopausal issues have more adrenal issues. And also, peri-menopausal issues, more adrenal issues, and I’ll even go one step further, cycling female issues, right? Definitely adrenal issues.

Uh, Amelia writes in, ” I’ve heard it takes one month to re-balance cycle for every year you haven’t had one?”. Yeah, that pro- that makes sense, I definitely agree with that, I mean, I typically see a major rebalancing in a- in a woman’s cycle within 6 to 12 months. And a major rebalancing is- I thi- I would s- call that, is about a 50% improvement. Alright, and then from there, we continue to compound that improvement month after month.

“Can someone with copper toxicity use a copper iud?”. Yeah, I mean, you can just make sure you’re doing extra zinc, put some extra zinc in your supplementation regime to help balance out the copper toxicity. That would be a good helpful approach ’cause you have the paragard or- is a copper iud and of course that can increase your copper levels. So you gotta be careful with that. You gotta weigh that out with your doc and see if you are really are copper sensitive. I have some patients that cannot do a paragard copper iud, they just can’t do it. Uhm, some can do it great and they have no problems. So you really gotta weigh those options out.

Uhm, “Can peri-menopause cause weight gain in the stomach? I’m 49 years old, no period for 7 months, gained 20 lbs. in the stomach in the last year and I can’t seem to lose it, is it just from unbalanced hormones?” So, remember, a lot of uhm, adrenal issues connect to peri-meno- menopausal issues. And a lot of adrenal issues are coming from cortisol imbalances. And cortisol has a direct effect on your tummy through just cortisol itself, the stress hormones can aff- affect the gut, and also through more sugar being released which can have an effect in insulin which can also affect your tummy. So, adrenal issues, have a major effect with cortisol, and also plug in and connect to insulin as well. So, great questions there.

“Do you think women with polymorphisms in COMT and MTHFR should not take the contraceptive pill? Controversial topic”, I know. Well, I know, in general like COMT like uh- catechol-O-methyltransferase. So when you see, uhm these types of issues, you may have issues with various adrenaline and just being able to deal with stress because these catecholamines are- like, you know, basically your stress hormones, your stress neurotransmitters. And MTHFR typically is gonna have a major effect on folate and then also affect B-12 and can affect methylations. So, uh- birth control pills deplete a lot of those nutrients. So yeah, I think what you’re saying is a very valid topic ’cause those issues can really have an effect on those nutrients. So if you are taking the pill, uhm- you really wanna make sure you’re supplementing with extra methylating nutrients, magnesium. In my line we’d recommend like B-vitamins synergy which has like the extra-activated folate, activated B-12, activated B-vitamins, and also a good multi on top of that, with magnesium and calcium, other important minerals that tend to get depleted.

Uh, “What would cause early spotting and irregular monthly cycle?”. That’s gonna because by typically lower progesterone or progesterone dropping out too soon in your cycle.

“Are there other conditions that cause hot flashes after menopause?”. Uhm, hard to say. I mean, you could- you may notice issues with blood sugar. Blood sugar ___[41:27] may get problem. A low thyroid, you may see some issues with that like if you have autoimmune flares on the hashimoto’s side. So yeah, there’s some potential connections there.

“Thoughts on carb cycling/keto for women with hormone imbalances? Ideal balancing diet?”. So, a lot of women do go with keto initially because they have insulin-resistance, and keto is very helpful with insulin resistance. But if you’re insulin-resistance is dialed in and you’re doing good with your blood sugar, some women starts to do better as they add in a little bit of safer carbohydrates, starches, squash, sweet potatoes, and they may even be better doing it cyclically. What does that mean? You’re kind of lower-carb keto for 2 or 3 days and maybe you have a sweet potato for dinner with your veggies and your meat. So, that I think is- is a very valid point, and I see that clinically.

Uhm, let me see here. Any other questions on hormones? I think we hit everything guys. Give me a thumbs up, give me a share, I appreciate it, make sure you hit that bell. People magically just go off my subscribe list if the bell is not hit. So make sure that bell’s hit, so you get all my notifications. Appreciate, uh today’s chat. Hopefully en- you enjoyed it, if you enjoyed it, give me a comment below. Let me know what you think. Any questions related to the topic, I’ll be back in and address them in future podcast or- we’ll respond here and I’ll look forward to connecting with you guys tomorrow, for a live Q&A.

You guys have an awesome day, and uh, go Patriots! Take care. Bye.


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What Your Brain is Really Hungry For

What Your Brain is Really Hungry For

By Dr. Justin Marchegiani

Alzheimer, dementia, and other neurodegenerative diseases are on the rise. Many people are under the impression that these diseases happen when you’re older, in your 60s, 70s, 80s… but this belief is wrong. Brain damage and deterioration actually starts when you’re young, in your 20s and 30s. It is only once enough damage has occured and symptoms start to show that a diagnosis is made.

How might a young person be causing such damage to their brain that they could end up with Alzheimer’s or other similar diseases? There are a few common patterns:

1) Insulin resistance: in some circles insulin resistance is even being referred to as Type III diabetes!

2) Autoimmunity: which can drive neurodegeneration in the brain.

3) Environmental toxicity: including heavy metals like aluminum, mercury and lead.

Today we’re going to be focusing on the effects of insulin resistance and its role in neurodegenerative diseases. Insulin is a hormone your pancreas creates that allows your body to use glucose (sugar and carbs) for energy. Insulin resistance is what happens when you consume too much sugar and carbohydrates, and your body stops reacting to insulin.

How does this relate to the brain? Well, it is a scientific fact that while the brain only represents about 5% of our body weight, it consumes nearly 25% of our nutrition and oxygen. When you consume too much sugar and carbohydrates, you become insulin resistant. Insulin resistance keeps the glucose trapped in the bloodstream and unable to be used for energy. Your brain becomes less and less capable of utilizing the glucose found in sugar and carbs for energy, and your begins to starve. If the brain is starving for glucose, the fuel needed to power our higher brain function is no longer accessible.

Optimize brain health by clicking here.

Hearing that these diseases can start if your brain is starving for glucose might lead you to believe that you should just consume more glucose, right?  It’s important to remember that excess glucose is what started this whole problem in the first place. Excess glucose in the blood is what caused insulin resistance, and also causes something called AGES(advances glycation end products). AGES are free radical magnets that damages our DNA, accelerate aging, and even cause wrinkles.

What the most up to date research is showing is that our brain can adapt to burning fat or ketones for energy. Essentially 80% of our brain can run off of ketones, so other areas that were perhaps starving now have access to a new fuel that can bring to life parts of the brain that may have been asleep.  One of the most popular fats that are being used are MCTs (medium chain triglycerides), which are abundantly found in coconut oil. These fats are unique because they are easily digested and converted into ketones which become brain food rather quickly.

Next time your sitting down to a meal, it’s a wise choice to avoid the excess sugar and refined junk and eat organic whole foods, especially vegetables, healthy fats, and proteins.  The solid portion of your brain is 70% fat, so make sure you get an extra serving of healthy grass-fed meat, wild salmon, and coconut oil. This will help your brain function at the highest level possible and help prevent the occurrence neurodegenerative disease in your future.

Click here for more ways to improve brain health and functioning.

The entire contents of this website are based upon the opinions of Dr. Justin Marchegiani unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Justin and his community. Dr. Justin encourages you to make your own health care decisions based upon your research and in partnership with a qualified healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Dr. Marchegiani’s products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products.