The Essential Oil Hormone Solution | Podcast #220

There are a lot of great practitioners out there who will help navigate that journey for you, but you’re making the best decisions and there is ownership of you. You are the “CEO” of your health.

In today’s podcast, be amazed as Dr. J interviews his lovely guest, Dr. Mariza Snyder, a functional practitioner and a renowned author of 7 books, the most recent being about one of her absolute favorite subjects – essential oils! Listen and learn about the importance of self-awareness, self-care, and other important recommendations for one to start implementing. Stay tuned for more and don’t forget to share!

Dr. Mariza Snyder

Dr. Mariza Snyder

In this episode, we cover:

04:53    The Luteal Phase

07:14    Estrogen-Dominance

10:29    Adrenals

13:26    Self-Healing Awareness

14:41    Plant-Based Medicine

18:13    Nutritional Compounds

24:11    Gut

25:49    Essential Oil-Wise to Support Luteal Phase

27:27    Perfume Alternatives


Dr. Justin Marchegiani: Hey there, it’s Dr. Justin Marchegiani. Welcome back to the podcast. We have Dr. Mariza Snyder on the show today. Dr. Snyder is a hormone expert and essential oil expert which is great because essential oils can be really helpful and they can really help with the stress response. So we’re gonna dive in to the hormones, we’re gonna dive in to some things that you can do right now to help kinda push your hormones back in the balance. Dr. Mariza, welcome to the podcast, how you doin’?

Dr. Mariza Snyder: Thank you so much for having me. I am great. So happy to be here.

Dr. Justin Marchegiani: Excellent. Very cool. So, I’m just curious, I was talking to you kinda pre to show. When I was uh, in doctorate school, you are actually right on the way out just a co- couple of quarters before me, so I actually remember you, we were kinda reminisce in a bit. And I wanted to- to- kinda, how did you make your exit on the doctorate chiropractic side into the functional medicine hormone side? What was that journey like for you?

Dr. Mariza Snyder: Absolutely. Well, there even reason why I pivoted the way that I did. So, 4, 15 years when I was little girl, 7 years old, I uhm- I basically had some pretty crazy head traumas, neck traumas, and that led to chronic migraine pain. And I was told, I can’t tell you how many times I was told I was gonna live with this pain, and I believed it for so long.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Well, fast forward, I, you know, growing up, I struggled, I missed- I missed slumber parties, I miss school, I missed all the fun things. I remembered as a kid, just thinking, “Man, I missed out so much on life” because I was in pain all the time like, these migraines would light me up for days on end. Just in a dark room with a cold cloth over my head, just praying to go to sleep. So, 24, I- I am a biochemist at elaborate floors of more national laboratory.

Dr. Justin Marchegiani: Oh, wow, yeah.

Dr. Mariza Snyder: And uhm- there was uh- a- a woman there who was- who- was like, “listen, we…”, uh “…I have a doctor who could probably get you out. And uhm, they get you from your- get well from your migraine”. I’ll be honest with you, at that point, it been 15 years, and I did not believe any of it. I was like, “I don’t know. This is I’m- this is my lot in life, missed thing, I’m- I’m stuck with this. I got my drive this- I’m gonna beat this sucker every single day or every other day. I’m good”. You know, “I’m gonna go and become medical doctor, I’m gonna go prescribe meds, just like I’m taking right now” [chuckles].

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: It- it’s just- it made no sense whatsoever, but when you don’t know that there’s a different paradigm, you just kinda follow along in suit. Uhm, because the practitioner was uhm- on the way home, I went and so- sought out care, and it was interesting, it was more of a functional practice of- that uh- and I didn’t realized what a functional practice was. I didn’t even know anything like this existed. I did have chiropractic growi- growing up and, I- unfortunately they weren’t able to clear out those migraines, but this practice had. Acupuncture, upper cervical, nutrition-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -the whole gamut of things, and after 90 days, after care, I was migraine free, and it blow my mind. So, that opened up the idea of- of this idea of healing that I’d never even thought of before. Literally switched past like that [snaps finger].This is over a summer. I was heading out to- to medical school, switched past over to-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -chiropractic school, this was the thing. Uhm, and, throughout that process, I was still educating and learning and thinking myself like how- how does the body have the ability to heal. And nutrition became a really big part of my life. So once I got into practice, most of women I was treating uhm- we’re dealing with hormone issues, I was also dealing with hormone issues, ’cause- ’cause why not have another health issue at the-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: after- after this other one.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: And I realized that although, uhm, chiropractic could be supportive to some of the things that it was really nutrition and lifestyle and really getting the core root of what was going on with them that was gonna move the needle. So, that became a big part of the practice.

Dr. Justin Marchegiani: That’s cool. I remember- if I remember correctly, you were an upper cervical chiro expert, right?

Dr. Mariza Snyder: I was because of the migraines. Yeah?

Dr. Justin Marchegiani: Yeah. And then I’m just curious, how far, like, if we just kinda quantify as a percentage, how far did the upper cervical get you versus the other half where you were incorporating more natural and- and nutritional and supplemental techniques?

Dr. Mariza Snyder: Absolutely. Well- if, you know, it was definitely case by case. Some people like myself-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -had [crosstalk]. And uhm- and it was uh-

Dr. Justin Marchegiani: [Clears throat]

Dr. Mariza Snyder: -things were wrong. There was  misalignments, there were problems, up at c122. So, but then there were other instances where a lot of of women that I was treating had migraine pain because of the-

Dr. Justin Marchegiani: Hormones?

Dr. Mariza Snyder: Yes. Hormones. Luteal phase-

Dr. Justin Marchegiani: Inflammation…

Dr. Mariza Snyder: -just drop of progesterone-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -and estrogen, and that was more of a lifestyle, nutritional, supplementation aspects. So, I would say the pain on a person, it they was hormone-driven, uhm, maybe 25%, uh 20% chiropractic, but really, I wasn’t making the changes until we stepped in to the nutrition and supplements and lifestyle.

Dr. Justin Marchegiani: Okay, got it. So, you’re kind of- it- the more on the physical stressor sides, the chiropractic so to help more of the alignment and- and the- the nervous system communication on the hormone side, we gotta make changes above and beyond. That totally makes sense. Now, you kinda went to an area that I love. You talked about the luteal phase. Can we just kinda- walk the average listener through what a typical cycle looks like. Follicular, lutial, and- and can you describe that physiology 101 for the listeners?

Dr. Mariza Snyder: Sure thing. So, if you’re still having a menstrual cycle, right? Which happens between like, I don’t know, ages 11 to 13 or so, all the way until where, well, until menopause. And menopause is defined as the disease of a menstrual cycle for about a year.

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: It’s usually when- unusually the lle- the- the- the roller coaster where we’re really feeling it, is in perimenopause, right? That’s when things really began to change. Well, basically- in the follicular phase, we’ve got the increase of estrogen levels, right? That kind of peaks at ovulation and then-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -starts to dip and go down. At that point in the luteal phase, you step into luteal phase, our progesterone levels begin to go up. Also, in the follicular phase, we got testosterone levels goin’ up too-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -naturally, but then everything starts to drop towards the end of luteal phase.

Dr. Justin Marchegiani: Right.

Dr. Mariza Snyder: And the pin on how fast those hormones are plummeting, really, dicta- reay kind of dictates P- PMS, right? The- the- that pre-menstrual cycle-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -is removing out of that. And so what I find that with women, if indeed we have a really sharp decline, or maybe they didn’t even necessarily have a big increase in progesterone to begin with, we’re gonna see things like migraines, we’re gonna see things like bloating, uhm, mood swings, a lot of those symptoms that we see around PMS. So that’s basically the physiology. And the only reason why we even get an increase in progesterone is if we actually ovulate. And-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -for some women, sometimes that isn’t even the case as well. So it’s really important to kind of- to look at all those things, to run tests. My favorite tests for looking in hormones is the DUTCH test.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: I usually recommend it during the luteal phase.

Dr. Justin Marchegiani: Okay, cool. So, you run ’em like a DUTCH Complete like arr- around day 19 to 22-ish?

Dr. Mariza Snyder: Things that like.

Dr. Justin Marchegiani: Kind of get that peak? And then do you run the- the month-long panels at all?

Dr. Mariza Snyder: I- I have not in the past.

Dr. Justin Marchegiani: Okay.

Dr. Mariza Snyder: But, I know how important those can be. Yes. And I usually- when I was testing, it was ever- I would do- I would test every quarter.

Dr. Justin Marchegiani: Yeah. Okay. Yeah, I mean I’ll typically run the month-long one, if there was more of a fertility case, but then, uhm- I’ll do a lot of a- you know, the snapshot in that- in that peak of a luteal phase, and I can’t tell you, I think uhm, you said it just right. I see so many women these days that are coming in with either mass- massive luteal phase defects where that luteal phase is just shortened or that progesterone’s just dropped out significantly, you know? Instead of 15 to 20 or so on that DUTCH test, they’re- they’re less than 5, even- and that’s really concerning. And then, that can approach these women into uh- maybe a- an estrogen-dominant situation. Can you describe what that is?

Dr. Mariza Snyder: Absolutely. So, estrogen- so- the- that’s really that you asked. Couple things about estrogen-dominance, we- you know, I get so many questions around this, you- you can actually have low estrogen and still be estrogen-dominant.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: So it’s really the relationship between estrogen and progesterone. And so often, given what we’re exposed to every single day, given our stress levels, so, not only lifestyle but also environmental, we still find that women tend to have more estrogen in the system than progesterone. And there are multiple factors, right? Progesterone could be stalling from our cortisol lab- you know, cortisol, the progesterone’s still. So we have- there’s a multiple facets but what we’re finding in a lot of women is that, just- just by the sheer fact of life that we’re living, estrogen’s gonna be- estradiol is gonna be higher than normal compared to progesterone. And, there’s a lot of thing that we can do about that for sure. And we can definitely get into that.

Dr. Justin Marchegiani: Yes. Yeah, very cool. And I’m even seeing a lot of women too that are at low progesterone but also low estrogen. Are you noticing that at all, too?

Dr. Mariza Snyder: Uh, that’s been me.

Dr. Justin Marchegiani: Oh.

Dr. Mariza Snyder: [Laughs]

Dr. Justin Marchegiani: And that’s just the hormone that just so depleted, right? Just-

Dr. Mariza Snyder: They’re so depleted. Yes. They’re absolutely depleted. And that has a lot to do with- I mean I- I find so often with women that it’s- a l- has a lot to do with the stress that that we’re living.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: You know, that’s very much like the key indicator, we just- we start burning out uhm- all of our hormones that we stopped creating the process where making them in a sufficient manner.

Dr. Justin Marchegiani: Very cool. I wanna highlight what mechanism because you know, you are upper cervical chiropractic specialist and we talked about chiropractic on the headaches side, and part of that can happen is, if there’s stress and inflammation in the spine by misalignment of poor movement, that’s gonna stimulate a lot cortisol to help with the inflammation. And we know, just for the listeners, cortisol pulls from progesterone, you mentioned that. So, when we get rid of the inflammation and we help the- the alignment and brain communicate better with the spine, that can decrease that progesterone still ’cause we’re not pulling from the cortisol as much. Is that sound right?

Dr. Mariza Snyder: It does. I mean, you also have to- I always tell people, you can’t chiropractic a green smoothie your way out of chronic stress.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: ‘Cause it’s, how you perceive the environment. If you’re continuing to create an environment, you know, I was talking about women being Rushy- having Ru- Rushing Woman’s Syndrome.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: If you are raising from one thing to the next, you’re gonna constantly being in a situation, this not- not medical terms, but I call it the Clutch the Pearls syndrome.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Where you’re constantly clutching the pearl. [Chuckles]

Dr. Justin Marchegiani: Exactly.

Dr. Mariza Snyder: So, if you’re constantly in that state, the- there’s gonna be no doctor that I know that there’s an- and there’s no supplement.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: There’s no green smoothies, there’s no nothing that’s really gonna-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -get our body back on track until we change the way that we are behaving at- in accordance to our environment.

Dr. Justin Marchegiani: Totally. That’s why a good functional medicine doctor, they’re gonna investigate the physical stressors. They’re gonna investigate the chemical stressors, that could be like you mentioned, the- the chronic stress state, the sleep, the poor food, the inflammatory food, the infections. The hormones maybe coming from the environment from food and pesticides, a d glyphosate, that totally make sense. And you mentioned the DUTCH testing. And that’s interesting because a lot of people I find at least more on the medical side I- I find it, they look at the hormones like the female hormones, the male hormones but, a lot of times they missed the adrenal hormone components. And what’s- what- [crosstalk]… yeah- yeah. Can you talk a little bit more about how the adrenals and why they’re so important to f- healthy female hormone function?

Dr. Mariza Snyder: Absolutely. So I- you know, I- you know, we necessarily see, you know, I was thinking about the- adrenals being the receivers of information. You know, they- they have a very important job, and that is to ensure, that is to listen to what the brain says, and you always talk about the Hypothalamic–pituitary–[adrenal] axis.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: Right, that relationship between-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -what we’re receiving, the HDA access-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: And- and that real- that information that’s related to the adrenals. And I- you know, I always talk about menopause and perimenopause being more of a stress condition than it is more of a hormone condition.

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: Uhm because of our- if our- if our adrenals aren’t supporting that, if our- if our chronic stressors are under-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -chronic stress under control, we’re going to throw those hormones out because it’s all interconnected.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: And at the end of the day, Dr. Justin and you know this more than I do, uhm, is that we are hard wired for survival.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: That- okay you had 2 jobs biologically that we’re supposed to do. 1, survive-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -and 2, pass down genes.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: So, reproduce, right? So kinda new- a new baby coming on the way, right?

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: And then when they have babies, well then you are an evolutionary success. So, our bodies, that’s the purpose. Now, hard-wiring towards survival means that we have to give up a lot of other thing. Our digestive system, our reproductive system takes a hit. You are a great thyroid expert, you know that a thyroid definitely over compensates for what’s going on as well.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: Uhm, but I wouldn’t necessarily see- I mean, and yes, you can definitely create adrenal fatigue over time. But you-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -think- take the wild for the adrenals to finally-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -say, “Enough is enough!”.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -“…I cannot take this anymore”, but I find that where we really gotta focus our efforts, is right here in the limbic system.

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: Uhm, that’s where we need to change the che- the chemical conversation. Because if that HPA access is continuing to up-regulate every single day-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Well, the adrenals are just like, “Dude, I’m just doing my job”.

Dr. Justin Marchegiani: Right.

Dr. Mariza Snyder: “…I just gotta- I gotta release this adrenal- this adrenaline, I gotta release this cortisol”-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -“…that’s my job, until one day, I am like, ‘I can’t do my job anymore. I can’t handle it'”. So, I would say that really, I always wanna work on the HPA access first-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -before I’d even begin to look actually at adrenal health. So, often I see that women have an up point of cortisol, maybe DHA is dysregulated, but the adrenals are still high functioning-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -still a while. Uh, so, that I usually wanna get to that root first which is I find right here.

Dr. Justin Marchegiani: Yeah. Very interesting. And it- it- it could be just semantics. I’ll look at the HPA access is like the person in the old horse and buggy that- that’s- that’s whipping a thyroid horse. The thyroid horse-

Dr. Mariza Snyder: Yes.

Dr. Justin Marchegiani: -[crosstalk] the adrenals, or the ovaries, so yeah, make sense-

Dr. Mariza Snyder: [Crosstalk]

Dr. Justin Marchegiani: …yeah, or the thyroid, or you can even go and- and-

Dr. Mariza Snyder: Or your gut, or your poor darn liver.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Our liver is just like, “I can’t pour out enough glycogen, like I…”, you know, that’s where we get diabetes. We’re getting-

Dr. Justin Marchegiani: 100%. So, you’re talking about really getting the communication and these feedback loops dialed back in, can we just go into some strategies, what are things that you are doing with the patients so that people are, you know, reading your work, what are the top 3 things and- and- and if you wanna qualify them with certain situations, that’d be helpful too.

Dr. Mariza Snyder: Absolutely. So, you know, we’re talking about kind of that- err- I think that first of all we just talk about the unexpected uhm, unexpected solution to health and radical self healing is awareness. You know, if you are not aware that you’re putting crap into your body, it’s really difficult to make those changes.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: If you’re not aware that you’ve had a gluten intolerance, you’re gonna probably still consume- eat glut- eat-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -gluten, right?

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: And if you’re not aware that you are running from one thing to the next, and that you’re living in a high stress situation, you’re just gonna keep doing what you’re doing. So, I think the first step really is self-awareness. Recognizing that something is not right. And I know-

Dr. Justin Marchegiani: Right.

Dr. Mariza Snyder: -for me, I thought I could green smoothie my way out of chronic stress-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: I also gonna get chiropractic my way out of chronic stress.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: And it didn’t work. I had to figure out that I kept- I had this operating system, this feedback loop that was firing-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -whether or not I knew it or not. So-

Dr. Justin Marchegiani: Yep.

Dr. Mariza Snyder: -I think some of the most important things is 1, we definitely live in a time of isolation. I’m so grateful for this technology that you and I-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -could be talking right here.

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: What would be even better is if we were right together, right?

Dr. Justin Marchegiani: Yes, totally.

Dr. Mariza Snyder: So, uh, having friends on speed dial, having people and family in your life that you can give hugs to, that you can- you can, you know, connect with, kind of boost that oxytocin level that dose that cuddle hormone-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Just being connected with people is number 1. Number 2, I love the power of plant-based medicine, so-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -I love essential oils-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: I think havin’ a tool, like a little oil like this-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Uhm, Bergamot and Lavender, we know-

Dr. Justin Marchegiani: Uh-huh.

Dr. Mariza Snyder: -research, time and time again, to lower serum cortisol levels, lower blood pressure and lower pulse point, but most importantly, they disrupt the cycle, from sympathetic to parasympathetic in that HPA access.

Dr. Justin Marchegiani: Okay.

Dr. Mariza Snyder: And I wanna disrupt the cycle.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: I wanna get ’em to habit. So not only does the chemistry by breathing the oils in-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -go to the limbic brain- limbic brain to disrupt the cycle. But the intention of you-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: Rubbing that oil, makin’ a decision like-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -“Hey, I feel…”-

Dr. Justin Marchegiani: Be aware.

Dr. Mariza Snyder: -“…like I’m having a moment”, yes.

Dr. Justin Marchegiani: You’re aware.

Dr. Mariza Snyder: And that begins to change the cycle as well.

Dr. Justin Marchegiani: Very cool.

Dr. Mariza Snyder: I’ll do thing- Yeah?

Dr. Justin Marchegiani: Go on. Go ahead.

Dr. Mariza Snyder: Oh, I got some other things. Uhm, I do love adaptogenic herbs-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: I do love Ashwagandha, I love Rhodiola, I- I love Holy Basil, any of them- all of them, it depends on that- I think you- I think testing is important to kinda understand-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -what’s going on. They do love those adaptogenic herbs, ’cause they also work on the limbic brain in the HPA access.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: I also think food plays a big role. I know I did say that you can’t bring some the- you’re out of chronic stress, but man, those important nutrients-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -can really help support the body if indeed you’re just in scenario right now where you’re like, “You know what Dr. Mariza and Dr. Justin, I hear you, but right now I’m- I have to live in this emergency state for a little bit”. You know-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -life dictates that for me. So those are some of the big things that I normally recommend for people than breathing, exercise, yoga, just pausing for a moment throughout the day, just that self-awareness, and then, self-care. I think self-care is the game changer. Uhm, so those will be some of the lifestyle techniques that I- I always recommend to women to start implementing. If they’re looking to start with that root thing, that HPA access, so that we can start to change the conversation that’s happening inside of the body.

Dr. Justin Marchegiani: Interesting. And that, when you’re looking at people, and let’s say you’re giving essential oils that are proven to lower cortisol, right?

Dr. Mariza Snyder: Mm-hmm.

Dr. Justin Marchegiani: Are- are- are you concerned if someone already has lower cortisol, or are you gonna be using other adaptogens that may, you know, have an up and down kind of bump in the direction. So, how are you evaluating that when you’re making specific recommendations?

Dr. Mariza Snyder: Absolutely, so yes. Could we have a situation where someone has significantly like at that point they de-regulate cortisol levels to so- such a degree-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -that they have- now they have lower cortisol levels? Yes. And so- and those ins- instances, I’m now looking more at and clearly, there are essential oils you can help boost cortisol, things like Rosemary, peppermint and citrus oils. So, we’re looking at a different response, and then yes, looking at different adaptogenic herbs to make those changes, that kinda- to heal the body’s- when we get you-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -to the base line, but also making those lifestyle changes as well. I mean, if in-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -deed, just grab in an oil just to have that moment for your-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -self. Uhm, I think- but that’s- it’s- that is important, it’s nice-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: Uh, especially they having a hard time going to sleep at night, uhm-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -but yeah, I mean, I think that the areas- I mean in- in all instances, everything is case by case.

Dr. Justin Marchegiani: Interesting. Is there any herb that you recommend that you feel just a really good multi-task, or where your cortisol could be low, and may give you a little pick me up, and it could also be a little bit high and you could be stressed that can kind of bring you down. Is there anything in that category?

Dr. Mariza Snyder: I think Rhodiolas would your- your go tea there. I like it the most, I feel like it- it really- and not only have support mitochondrial function, which-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -I love, uhm, but it also can meet you both ways. I think more than Ashwagandha, uh, Rhodiola really is one of those adaptogenic herbs that will kinda give you what you need.

Dr. Justin Marchegiani: Okay, cool. I wanna go a little bit- I’m gonna go a little bit deeper here. Can we talk about some of the nutritional compounds that are in these herbs? Are you aware of some of the- uh you- we talked about the adaptogenic components, other nutritional compounds that we’re also getting from some of these essential oils that are helping us, as well? Kinda like vitamins and minerals or polyphenols, what’s happening there?

Dr. Mariza Snyder: Yes, essential oils aren’t nutrition. Uhm, some of them can definitely have antioxidant benefit especially like citrus oils-

Dr. Justin Marchegiani: ‘Kay.

Dr. Mariza Snyder: -but I don’t necessarily consider them nutrition-

Dr. Justin Marchegiani: Okay.

Dr. Mariza Snyder: -I’m so much as like consider them as being- uhm, it’s powerful- kind of- uh, organic chemistry, right? Uhm-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -really can work in the body and aid in the body. So, nutritionally, I usually still lend to a p- uh- plant-based nutrition or supplementation. You have someone is-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -deficient in magnesium, well, we gonna get them with some magnesium.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: And B-Vitamins then activated B-Vitamins are gonna be what I recommend. But usually when I use essential oils for most importantly, is cre- is- is- is to bridge the gap for the lifestyle changes that we know we should be doing, we just aren’t doing. So, for instant, if we are going to- if we’re having a hard time going to bed every single night-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -because, we cannot shut up brain, or-

Dr. Justin Marchegiani: Totally.

Dr. Mariza Snyder: We- we just- we just prefer to work instead. Whatever that maybe, you’re in your, you know, you’re in your phone, you’re on your iPad, or whatever that maybe, like I was just in the phone with my grandma today, one of my- I go look on both my grandmas for- for different reasons, but-

Dr. Justin Marchegiani: Mm-hmm, mm-hmm.

Dr. Mariza Snyder: – my uhm- my little Mexican grandma, my mother’s mother, she- I was- I called her and my grandma is like, “You know, everytime- every night before we go to bed, I just watch you. I watch you before I go to bed”, and I’m just like, “Okay”. I’m like, “Well, do you learn anything from me?”, and she’s like, “Yeah, I don’t know at all”, you know, she’s [laughs]. I think, “Grandma, you shouldn’t be on your iPad before bed”. Look [laughs]-

Dr. Justin Marchegiani: Totally, totally.

Dr. Mariza Snyder: Just killing her- anyway, it’s just a really funny moment, but I think so many people like my grandma where they’re on, YouTube or they’re on- I don’t-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -even know where she’s watching, we have no idea. Uhm, but, having a ritual where you’re utilizing the essential oils, like the process of Lavender, Bergamot, Cedar Wood-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -clary sage, whatever those oils are, getting into the habit of creating this behavior, but also knowing that that chemistry is helping to really calm down the brain as well ’cause they’re all very common essential oils. So that’s kinda how I love to leverage them. How can we use them to set a- set a mo- uh, evening ritual where you’re calming down the brain and going to bed. How do you use them to go to the gym every single day? Like, I love peppermint and wild oranges, an instant energizer body. How do you use them for productivity and- and energy and alertness, and working memory. Right, a combination of peppermint-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -Rosemary and Frankincense, that’s gonna do that for you. So I think when it comes to these lifestyle changes, the self-care, if we have these oils that can punctuate how we live our life, that’s how I love to use them in aiding in the- in the daily decisions that we make, either, hopefully you start your day with great decisions that lead to more great decisions, and you’e leveraging that chemistry to just have a really great experience.

Dr. Justin Marchegiani: Very cool. Is there anything you used synergistically outside of diet and lifestyle? Are there any of nutrients that you will use supplementally synergize with essential oil? Uh- I’m just kinda throw it out there, maybe like magnesium and lavender, or something like that, is there anything you seen clinically?

Dr. Mariza Snyder: Yeah. Uhm- gosh, that’s a good question. You know what, I- I- no, and clinic- clinically, yes, I guess maybe case by case for me-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder:-I don’t know if there’s a lot of research where we’re seeing a lot of the combinations of herb-herbs, and, I mean oils, or s- or vitamins and minerals and oils. Uhm, we- I- what I do know is that yeah, like when you’re heading to bed at night, let’s say it’s lavender, and maybe you’re using something like melatonin or maybe-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -something like uhm, eating cream rose, I think-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -that those have a really profound impact. UHm, let’s say that you are using uhm, like- like, I recommend a lo- I recommend turmeric, I recommend omegas, I recommend uhm, something for cognitive function in particular but I also know that rose mary, the chemical constituent rose mary which is 1/8 ___[22:06]-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -actually helps to increase acetylcholine in the brain. And so [crosstalk] as well. Yeah. So, pair as well as, I think important supplements that can help um, boost brain function. But just breathing in rose mary will inc- will literally increase working memory by 75%.

Dr. Justin Marchegiani: Awesome.

Dr. Mariza Snyder: Right there in there, without taking omegas. But you should be taking omegas anyway. DHEA, so- so just- err- uh- DHEA- DH- err- gosh I’m having a- anyway, the point is this, when you’re taking-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -those omegas, you’re boosting memory and- and brain function. So, I- I guess in a sense, I’m usually telling people to be consistent with them, uhm, so that you’re getting the response that you want, but I also- I’m recommending supplements, so it feel like when it’s- we’re coming to long ___[22:47], and-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -really changing those biological processes, then we have that in place as well.

Dr. Justin Marchegiani: Okay, very cool. Alright, I got some rapid fire questions here. I’m putting you on the spot, you ready?

Dr. Mariza Snyder: Alright. Yeah.

Dr. Justin Marchegiani: Alright, you already said 1, I- I’l answer it for you. Memory, your favorite essential oil sounded like it was Rose Mary-

Dr. Mariza Snyder: Rose Mary, yes.

Dr. Justin Marchegiani: Okay. Good. Anxiety, favorite?

Dr. Mariza Snyder: Anxiety. Uhm, lavender, lavender and vetiver.

Dr. Justin Marchegiani: Good. Depression?

Dr. Mariza Snyder: Depression. Oh my goodness. Uhm, frankincense, Meliss- I- I’m giving you another one. Frankincense, Melissa and citrus oils.

Dr. Justin Marchegiani: Excellent. Uh, pain in the joint?

Dr. Mariza Snyder: Wo- I would say well, camphor is really what I’m looking for, but camphor can be found in winter green, uhm-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -I also love copaiba, uhm, for-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -it’s connection with the uhm- the- oh my gosh, the- kind of work similar to CBD so it connects with the CBD receptors it’s CBD-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -receptors in the body-

Dr. Justin Marchegiani: I know what you’re talking about, the- the- that endocannabinoids system, that-

Dr. Mariza Snyder: Yes.

Dr. Justin Marchegiani: -makes sense.

Dr. Mariza Snyder: Yes. exactly.

Dr. Justin Marchegiani: What about brain fog?

Dr. Mariza Snyder: Uh, brain fog. So, I love Rosemary. Rosemary, peppermint, frankincense, same kind of concept there.

Dr. Justin Marchegiani: Good. How about something like an ear infection?

Dr. Mariza Snyder: Uh, ear infection. So, I love Tea Tree Oil. So, Tea Tree Oil is a great antiseptic, antibacterial, but le- so my go tea for- for an ear infections is Tea Tree, Basil and lavender around the ear, diluted at around 25% dilution.

Dr. Justin Marchegiani: Okay. And is there any other uhm, chronic issues or situations that you get asked a lot, that I didn’t mentioned yet?

Dr. Mariza Snyder: Gut-

Dr. Justin Marchegiani: Oh!

Dr. Mariza Snyder: -all day, everyday.

Dr. Justin Marchegiani: Woah.

Dr. Mariza Snyder: [Laughs]

Dr. Justin Marchegiani: [Laughs]

Dr. Mariza Snyder: Right? So- uhm, so in- you know what, gut is- it’s a whole nother conversation, and it’s- it’s- it’s- it’s actually a hundred different conversations.

Dr. Justin Marchegiani: Totally.

Dr. Mariza Snyder: So, let’s say you are having an acute gut issue, maybe you decided to eat pizza on a friday night and you knew better, and you didn’t-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -take your enzymes or, you took- you didn’t take- you took your enzymes but still it didn’t matter-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -because you have gluten and- uhm, and dairy sensitivities. Uhm, so I love a blend- it’s a blend- it’s a combination of phenyl, peppermint and ginger.

Dr. Justin Marchegiani: Oh. Yeah?

Dr. Mariza Snyder: And I’m not saying that those oils are gonna cure what’s going on there, but at least it’s gonna lessen the acute symptoms.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -and that’s happening inside of the gut. And so, I just make up a du- a little roller like this, 10 to 15 drops of each.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: …over the stomach, and those 3 oils have been researched, particularly because of the herbs, the chemical constituents in those oils have been really, calm down things like bloating, constipation, diarrhea, and- and just in pain in the gut that could be happening in a small-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -and large intestine.

Dr. Justin Marchegiani: Yeah, and a lot of those oils too, stimulate uhm, acid production, enzyme production naturally as well. So, you’re- you’re kinda get in the body to pinch in help as well?

Dr. Mariza Snyder: Yeah, and peristalsis as well. So removing-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -through, yeah. And, another one, I mean, I traded migraines and headaches for so many years.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: I do love, uhm, a combination of lavender, peppermint and frankincense, that’s kind of my power combo-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: Again, in a roller, 10 to 15 drops of each, uh- you know, for me, it’s- it’s- if you can catch that migraine on time, it’s always cervicogenic for so many people.

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: -so always start back here, uhm, and just get those oils on, you know, every 30 minutes, uh, so that you- maybe- so that, that’s the option instead of uh- a non -steroidal anti-inflammatory.

Dr. Justin Marchegiani: That’s great. And you mentioned earlier, we talked about luteal phase defect and our low progesterone in that last half of the cycle, is there anything essential oil-wise that you do to help support that luteal phase, that low progesterone/ PMS, hormonal environment?

Dr. Mariza Snyder: Absolutely. So, there, my gotu oil I called the “Beyonce” of hormonal oils-

Dr. Justin Marchegiani: [Laughs]

Dr. Mariza Snyder: [Crosstalk]. I have a blend, it’s called my superwoman blend, and it’s-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -actually what this is right here. This is what I’ve been holding up all day.

Dr. Justin Marchegiani: Oh, cool.

Dr. Mariza Snyder: And they’re designed for- yeah, it’s kinds luteal defect, helping to boost progesterone levels. So, the 2 gotu oils for boosting progesterone levels are gonna be, uh, clary sage and thyme. Now, thyme, not the sexiest smell in the world, but you can-

Dr. Justin Marchegiani: Right.

Dr. Mariza Snyder: -definitely make up a blend like that-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -on the bottom of the feet or right over the ovaries. This one doesn’t have thyme, but it has geranium which can also do that. What I also love about geranium is- it helps the liver in the de- in the pa- phase 1 and phase 2  of the detoxification-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -pathway, it helps to breakdown uhm estrogen metabolites. So I do love geranium for that. So, this is 12 drops of clary sage, 10 drops of lavender, 5 drops of geranium, 5 drops-

Dr. Justin Marchegiani: Ah.

Dr. Mariza Snyder: -cedar wood, it’s a- it’s a blend; and 4 drops of lengling, and so, applyin’ it over the ovaries or right here, ’cause remember-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -oils definitely goes straight into the bloodstream.

Dr. Justin Marchegiani: Exactly.

Dr. Mariza Snyder: Right here in the wrist, I love it on my neck as well, uhm, and just a couple times a day, uhm, it’s also great for mood support and it’s great for cravings and energy. So, it’s kind of a multi-faceted essential oil, but I have women using it for period, their periods and PMS all the time, all over the country and all over the world, and with great success. So I love this one.

Dr. Justin Marchegiani: Very cool. Very cool.

Dr. Mariza Snyder: Yeah.

Dr. Justin Marchegiani: Now, one of my biggest pet peeves, just ’cause this could be a hormonal stressor as well, and it just drives me crazy, is when people have- when guys either have like a strong, uhm, cologne, or womens have a s- have a strong perfume on, what can be an essential oil alternative, you know, for- for a woman or for man, that can kinda still give ’em that- that smell that they want but it wouldn’t be non-toxic and drive people crazy?

Dr. Mariza Snyder: Oh, silly. I have a lot of perfume blends. If I, you know- it depends on the person. The-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -Superwoman blend for women, a lot of women wear as perfume-

Dr. Justin Marchegiani: Great.

Dr. Mariza Snyder: -’cause it smells great, and who doesn’t want side-benefits, right?

Dr. Justin Marchegiani: Yes. Yeah.

Dr. Mariza Snyder: That’s what I love. But with guys- so, you think about most colognes, but ___[28:04] is vetiver, and-

Dr. Justin Marchegiani: Yup.

Dr. Mariza Snyder: Vetiver is a powerful neurological essential oil.

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: And fortunately, you’re getting a synthetic virginning cologne, and so- uh- you know, uh- vetiver, citruses, myrrh’s, frankincense, sandalwoods, those are all oils that are used in colognes. I don’t have a very specific male cologne recipe  in my ha- in my head right now, but I- there’s a lot of them out there.

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: And a lot of guys use them. My husband made up his own thing-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -I have no idea what’s in that blend. But he does his thing, and then for me, I’m obsessed-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: -with jasmine and rose. So, I wear a combination of jasmine and rose. Jasmine, what’s- what’s really interesting, is that jasmine’s been researched to help women overcome postmortem depression. Uhm, it’s also a libido booster-

Dr. Justin Marchegiani: Okay, cool.

Dr. Mariza Snyder: -and then rose is just a really powerful, beautiful essential oil so, I- that combo is just so beautiful to me, my husband loves it. Jasmine’s intoxicating. And so, a lot of women really grabbed a taste towards jasmine, yeah.

Dr. Justin Marchegiani: Very cool. Now-

Dr. Mariza Snyder: Yes.

Dr. Justin Marchegiani: -do you manufacture your own essential oils or do you have certain lines out there that you like or you think are really high quality?

Dr. Mariza Snyder: I think- you know, I think when it comes to the “I do not manufacture”-

Dr. Justin Marchegiani: Mm-hmm.

Dr. Mariza Snyder: -oh my goodness, the- the- the- the amount of effort and time and research that goes-

Dr. Justin Marchegiani: Totally.

Dr. Mariza Snyder: -into the oils is just- just- profound. Uhm, I- when I always is when you’re researching the company, and I do have a company that I prefer, but make sure that that company, they- they tell you where they’re sourcing their oils. Where are these oils coming from?

Dr. Justin Marchegiani: Hmm.

Dr. Mariza Snyder: Each and everyone of those oils that I mentioned a minute ago, and that superwoman blend, come from a different country-

Dr. Justin Marchegiani: Okay.

Dr. Mariza Snyder: -all over the world. And, different, very small batch growers are growing those in- in a very, you know, in an organi type of setting. Then, once those oils are produced and harvest in a sustainable way, I wanna know how they’re tested. Do they use gas chromatography, are they using spectroscopy, are they using chirality testing, are they using microbial testing, how are they testing these oils, and, as third party uh- laboratory should be testing the oils to really guarantee their efficacy, and if it’s a really great company, they will be a lot number on that label, where you can pull up the testing of that batch. So-

Dr. Justin Marchegiani: Oh, very cool.

Dr. Mariza Snyder: -that’s what I’m looking for when I’m looking for oils. Because if you’re trying to use these re- ther- therapy to benefit, well then you just don’t wanna put crap on your body.

Dr. Justin Marchegiani: Got it. Is there any s- is there any specific essential oil companies that you know of that- that meet those standards you just mentioned?

Dr. Mariza Snyder: Yes, there are couple. My gotu favorite is Doterra. I’m a big fan of-

Dr. Justin Marchegiani: Okay, Doterra, cool.

Dr. Mariza Snyder: -I’m a Doterra girl.

Dr. Justin Marchegiani: Cool.

Dr. Mariza Snyder: And uhm, I’ve been using them for years, I’ve been recommending them millions of people as well with great success, so I feel really confident with the quality control that they implement.

Dr. Justin Marchegiani: Awesome, very cool. And I know, today, we are really getting into a lot of the essential oils and the hormone connection which is great. And this is kind of I think a perfect segway for you to kinda dive in and just keep people a little sneak preview about your book which is gonna be I think a more in depth version of this conversation.

Dr. Mariza Snyder: Absolutely. So, I have a new book comin’ out, I don’t know when this is airing, but do have a new book coming out, it’s called “The Essential Oils Hormone Solution”. And it literally, not only do I go into the “Why”, the- the- the chemical, biochemical “Why” of what’s going on in the body-

Dr. Justin Marchegiani: Yeah.

Dr. Mariza Snyder: So often women are like, “Well, what do you have for menopause?”, and I’m just like, “Well, what about menopauses that concern?”, you know? And- and what if- what if it isn’t menopause at all, maybe it’s something else? And so, understanding the- the chemical implications, what’s going on with hormones, then giving women oils, protocols, self care, it’s all built in, and then I have a 14-day hormone reset program that contains my hormone trifecta which is a combination of food, oils and self care. And when you put those things together, it really is magic. So, that is what the book entails. 400-pages.

Dr. Justin Marchegiani: Woah!

Dr. Mariza Snyder: It’s a very big book, with 40 pages of bibliography. So, I did hundreds of hours of research for this book.

Dr. Justin Marchegiani: That’s amazing.

Dr. Mariza Snyder: Yeah.

Dr. Justin Marchegiani: And then, the book’s called what, “The Essential…”, can you repeat it again?

Dr. Mariza Snyder: Oh, yeah, “The Essential Oils Hormone Solution”. Here is this what it-

Dr. Justin Marchegiani: Yes.

Dr. Mariza Snyder: -looks like, and it’s on-

Dr. Justin Marchegiani: Perfect.

Dr. Mariza Snyder: -it’s on Amazon. It’s selling like “Hot Cake” which makes me so-

Dr. Justin Marchegiani: It’s already out now?

Dr. Mariza Snyder: -happy. Yes. Well, it’s- it’s right now, it’s for pre-order but people were buying it.

Dr. Justin Marchegiani: Great. I’m gonna put the links- the Amazon links down below. So, if anyone’s listening to this on the iTunes or YouTube, just click below and you’ll be able to get it. That’s awesome. Is there any other information at all you wanna share with the listeners here before we wrap up?

Dr. Mariza Snyder: I would just say, I think the biggest message that you and I probably bring to table is that, you really have- you really are the CEO of your health. You know, we have a- there’s a lot of great practitioners out there like Dr. Justin and myself who can really guide you on this path, but just know that there is- there’s ownership for you. And that, you don’t have- you know, you don’t need to be told that you’re just gonna have to live with this disease or this condition, but there’s definitely a way out, it’s just a matter of deciding that yes, “It’s time for me”, and just reaching out to people like ourselves, be- listening to Dr. Justin’s podcasts, because that’s exactly what we’re here to to do is to really navigate that journey for you, but you’re making the best decisions for health.

Dr. Justin Marchegiani: Very cool. And if listeners wanna get more information about you, where is the best place to go?

Dr. Mariza Snyder: So, I have a podcast myself, it’s called the Essentially You podcast, and it’s a great place to find me, it’s everywhere. Uhm, I have other books as well, but then, my website is, I have fun, awesome little chit-chit there, on the top 5 oils for hormone balance, you guys go and grab that, and then if you do pre-order the book, I have $300 worth in bonuses that instantly gets delivered to your inbox, so you can get started right away. So, even if you’re like, “Man, I just- the bo- book isn’t gonna be here for a couple weeks”, no worries, the bonuses will hook you up, until a book arrives.

Dr. Justin Marchegiani: Very cool. And just for the listeners, there’s a silent “Z” in that name here. D-R M-A-R-I-Z-A-[dot].com, and I see a cool little optin’ on the top 5 essential oils for hormone balance. So, while you’re up there, feel free and get that. Dr. Mariza, anything else you wanna add?

Dr. Mariza Snyder: That- I think that’s it, I think we covered a good amount of information. Dr. Justin, thank you so much for the great questions, it was such a pleasure to be here.

Dr. Justin Marchegiani: Thanks to in the part of the podcast. Thanks Dr. Mariza!

Dr. Mariza Snyder: Mm-hmm.


The Essential Oils Hormone Solution 

Tips for a Healthy Pregnancy – Dr. Justin Podcast #153

Dr. Justin Marchegiani and Evan Brand dive into a discussion about having a healthy pregnancy. Gain some valuable information as they talk about nutrition, diet and lab tests before and during pregnancy.

Learn how different factors such as estrogen dominance, autoimmune  diseases, toxic substances and nutrition issues affect fertility. Find out about In Vitro Fertilization (IVF), understand the reason why some people choose this option of conceiving and discover some of the natural solutions and recommendations to health-related and nutrition issues that hinder people from having a natural and healthy pregnancy.

 Tips For A Healthy Pregnancy

In this episode, we cover:

11:08   Factors affecting fertility 

21:36   Food sensitivities and miscarriages

25:00   In Vitro Fertilization

35:14   Blood sugar in pregnancy

36:08   Thyroid issues in pregnancy



Dr. Justin Marchegiani YouTube channel




Dr. Justin Marchegiani: And we are live here. Dr. J in the house with Evan. Evan, how you doin’ man? How’s your day goin?

Evan Brand: Life is good. How are you doin’?

Dr. Justin Marchegiani: Very good. The first podcast officially as a dad—feels really good and really rewarding. Little bit sleep deprived and my wife is taking the brunt of it, but I’m doing my best to uh— be a supporting about— a very supportive husband providing all the nutrition she needs, cooking all her meals. We got a little fridge right outside the baby’s room put upstairs. And I got—it’s stuffed with bone broth, Kombucha, sparkling mineral water, uh— filtered water electrolyte and hence, she’s got a handful of meals. Paleo meals I already prepared. She’s got some really good healthy snacks. She gets some collagen smoothies and shakes up there, so I got her like stock up some. My goal is to try to feed the baby uh—kinda proxy, right? getting all the nutrition she needs and therefore, she could take it in as easy as possible and then provide the best nutrition for the baby.

Dr. Justin Marchegiani:  Absolutely, man. Well, congratulations. I’m super happy for you. It’s been a— been a long time coming. When you’re waiting for stuff like this, a day feels like a week and a week feels like a year, so—

Dr. Justin Marchegiani: Yeah. And the baby’s name is Aiden Raymond Marchegiani. And Aiden means little fire, so. The boy— we’re really, really stoked to have him and we’re just trying to provide him as much nutrition as possible. He was in the NICU for a day and a quarter. Maybe two days, let’s just say. He had a slight collapsed lung birth. He was doing great and then as soon as the cord was cut, which we’re trying to delay clamping as much as possible—but it’s a C-section, right, so like you know while the baby’s got the cord attached, you know, mom’s open bleeding, right, so with the weighing out the benefits—

Evan Brand: Ahh..

Dr. Justin Marchegiani: Normally we’d wait ‘til that cord with pulse turn til it’s white. You know, go white and such, which maybe 10 minutes or so. We didn’t quite have that luxury, so, you know, we framed it out with the OB. Had a time we delayed as long as we could, and as soon as that cord was cut, he crashed. His O2 suction levels dropped. They put a  C Pap on him. They got his O2 up; they run a chest x-ray and right after there’s a slight collapsed lung. But in a day and a quarter, day and a half—healed.

Evan Brand: Wow!

Dr. Justin Marchegiani: So he was super, super resilient. And we just—you know, we have to contribute the fact that my wife’s nutrition and sleep and all that stuff was just really great during her pregnancy. And that probably attributed to his resilience.

Evan Brand: I’m glad it all worked out.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And you guys are home safe.

Dr. Justin Marchegiani: Yeah. I mean the NICU docs were pretty—I think very shocked. They were telling me if we could be in there up to three weeks. And she was like, two days.

Evan Brand: Wow!

Dr. Justin Marchegiani: So it was pretty great to see that.

Evan Brand: So the people are probably like, “what happened?” you know, “You guys talk so much about holistic self why a C-section? Do you care to elaborate some of that?”

Dr. Justin Marchegiani: Oh, yeah. Let’s talk about that. I’ve talked about it in other podcast, in other episode, but people may not listen everything, so will kinda make it so it all connects. My wife had a large fibroid removed about a year and a half ago— about the size of a baby’s head. There’s a very big fibroid. She’d taken birth control pills for 15 years, you know, in her late teens into her early 30s.

Evan Brand: You think that might have caused it?

Dr. Justin Marchegiani: I think that’s a contributing factor if you listen to my podcast with Dr. Horwitz, he’s a fibroid expert and he says that you know, estrogen dominant states can definitely drive fibroid growth. There’s not a lot of research on it. I don’t think there’s gonna – there’s gonna be a lot of motivation to do a lot of research on it, but we know estrogen dominance can cause things like fibroids to happen. And then the question is, what can drive estrogen dominance, right? We know stress drives it. we know, you know, estrogens drive it. We know phyto estrogens, right? We know low progesterone states can drive it. We also know birth control pills can drive estrogen dominance, right? So it’s the milieu, the hormonal milieu. And also, just not getting pregnant. Getting pregnant later in life can also drive it because when you get pregnant, you’re really driving a progesterone dominance state. And then breast feeding, right, you’re keeping progesterone levels really high, too. So my wife got pregnant at age 40 and we decided that to get the fibroid removed just because one, it was so big and number two, we just have a smaller fertility window.

Evan Brand: Yeah.

Dr. Justin Marchegiani: The fertility window’s a lot smaller and we can get that fibroid removed we can get pregnant like that. And again, her hormones are that of a young 30 year old woman. So we had done work with her, helping her hormones, PMS, all that was really good. Her hormones were that of someone 10 years younger. She just had this big fibroid which acted like an IUD, right?

Evan Brand: Wow!

Dr. Justin Marchegiani: Intra Uterine Device which basically just— imagine this fibroid there just sucking up blood flow so that when an egg comes in, it’s not gonna be able to stick because there’s not enough blood flow to sustain it, right? So soon as that fiber was removed, we get pregnant. Two weeks after it was removed. And the doctor was like, “Okay, you know, you can try.” But he’s kinda not expecting much. But as soon as we tried the first time, we got pregnant. And yeah, we actually uhm— lost that baby but it was a blighted ovum. So none—is really a baby. There was no like heartbeat or anything, which is the sack but we lost it which was tough, but you know, we just kind of attribute it to the fact that she’s went to a major surgery, right? She was under general anesthesia. She’s on pain meds. Probably wasn’t the best time to try to get pregnant. We only did because the doctor said it would be okay. But as soon as you know, that— the hCG dropped and she got her period back, we tried again and then we got pregnant. So uh—that’s the baby we had now, Aiden, so, we’re very stoked. So the reason why we had to do the C-section, coming back, is because the incision was along the posterior section of the uterus which had kinda weaken the uterus which had her increase her chance of a uterine rupture. And because of that increased chance of a uterine rupture—the uterus rupture is you know baby and mom can die. So they had to pull the baby out four weeks sooner week 36 just to ensure that uterus wouldn’t rupture. It’s only a 1% chance but you know we spoke to midwives and OBs and no one recommended— no one would even do a natural birth.

Evan Brand: Oh, wow!

Dr. Justin Marchegiani: Just because of the liability was so high. But I was able to watch the whole entire surgery. And I literally—you know, they her uterus in her hand and I was like, “Hey, can you look at the backside?” This is after the baby was born. They turn at the backside. “How’s the posterior incision? Let’s look at it.” And she was like lookin’ at it, “I can’t even see an incision.” So the uterus healed up so strong and what I attribute that to is I have my wife on the Tru Collagen every day. She was doing about 30 g of collagen every single day. And I know that those collagen, amino acids had to— made a huge difference in helping to provide extra building blocks to the— to her uterus to heal up. But they couldn’t even see an incision to the back.

Evan Brand: Well, also, you mentioned she had no stretch marks, too, which is a pretty remarkable testimonial.

Dr. Justin Marchegiani: Yeah. She had no stretch marks. Again, the baby came four weeks early so some women will say, “the stretchmark comes that last 2 to 4 weeks” But again, in my opinion a lot of people are getting a lot of their protein from muscle meats which is, you know, still good. But, again, collagen is gonna be connective tissue protein. That’s ligaments, tendons, cartilage, hide skin, right? So you’re getting a lot more building blocks that are gonna help the connective tissue and the skin. And a lot of what’s happening with the stretching of the skin and the fascia and all that tissue is gonna be connective tissue-based. So I think that providing one, lots of healthy fats and two, providing all the extra collagen peptides really help number one, her uterus heal, number two help the skin heal and number three, I also think it will help uhm—the breast. A lot of women, their breast tissue kinda gets flattened and kind of, you know, really just kind of uhm—just flattened a bit. Maybe the breast will start sagging and hanging and such after a long time of breastfeeding. I think the connective tissue support will also help the integrity of the breast tissue as well.

Evan Brand: Ahh.. That’s interesting.t I believe that there’s probably gonna be benefits. I mean, I wonder if we compared standard American women compared to hunter-gatherer women. Like what was the difference in their skin quality probably huge difference coz the hunter gatherers eating the marrow and the collagen and the bones and doing more stuff than typical women do.

Dr. Justin Marchegiani: Yeah. I mean if you look at some of the anthropomorphic kind of research, like they talk about literally taking the organs and like harvesting them. And the organs would be like literally given to the women that were fertile, that were trying to get pregnant because they knew the organs were incredibly, you know, nutrient dense. And there’s also research to these women like would literally give birth uhm— that— that day and be back out on the field later on that day or that next day working.

Evan Brand: Wow!

Dr. Justin Marchegiani:  It’s crazy, right? I mean they probably had a lot less stress in her life, too, right?

Evan Brand: True.

Dr. Justin Marchegiani: Very, very little stress, but still uhm— it’s amazing what the body is capable of doing. So that is kinda like my back stories that just kinda summarizing uh—history of fibroid and there are natural ways to reduce fibroids and I’ve seen them reduced and it help with those kind of situation in the past. We just—we’re dealing with the time window, right? And if a woman’s like in her 20s or early 30s and has a few years, hey, that may be a good thing to try, but in my opinion, uhm— you know, if you’re up against a pregnancy window, getting it surgically removed is good. But if you listen to my interview Dr. Horwitz he said women that he’s removed the same fibroid three times. So what does that tell you? That just because you remove a fibroid, that does not fix the underlying issue of why that fibroid is growing anyway, right?

Evan Brand: That makes sense. So the birth control, for example, could’ve been one thing. There gotta be an insulin components, my guess.

Dr. Justin Marchegiani: It’s probably an insulin component, too, for sure. There’s probably toxicity component too, right? Coz a lot of toxins are estrogenic compound.

Evan Brand: Yup. Right.

Dr. Justin Marchegiani: So there’s some of that. So we’re trying to do our best to support all that and again one, of the protocols will be doing is using some systemic-based enzymes or peptidase etc. to really help. She has one tiny fibroid still there. It’s in around the fallopian tube. The fallopian tubes is so patent. So it’s still open and I literally was like, you know, you’re yellin’ at the OB, “Hey, can you check out her left fallopian tube. How does it look?” She’s like, “Oh, that little, tiny fibroid—like you know, half of the fingernail, still there in the fallopian tube, but it’s not growing. So, you know, our goal is we’re gonna try to work on dissolving that one naturally uhm—you know, over the next few years.

Evan Brand: That’s amazing. So when it had to be cut out, you can just go in there with tweezers and yank it off or something, it’s not that easy.

Dr. Justin Marchegiani: Yeah. The fallopian tube’s kinda—you could, but you’d compromise the fallopian tube.

Evan Brand: Oh, wow!

Dr. Justin Marchegiani: And the fallopian tube is still open, so it doesn’t make sense. She had one little, tiny fibroid actually uhm— there at the incision site, where they cut the uterus to deliver the baby. So actually, she got two for one. They removed that little baby fibroid at the incision.

Evan Brand: Wow! Did you see that? What did it look like?

Dr. Justin Marchegiani: I mean, it’s just—I got pictures of it, but uh—yeah, it’s just like a little, like mini golf ball.

Evan Brand: Really? And what—what’s the texture of it?

Dr. Justin Marchegiani:  It’s kinda like uh—fibrous.

Evan Brand: Oh, that makes sense.

Dr. Justin Marchegiani: So like uhm—I’m trying to think of a consistency— it’s just— it’s dense but it’s a slight bit of squishiness to it, but it’s still—

Evan Brand: Yeah. That makes sense. That’s amazing.

Dr. Justin Marchegiani: Yeah. Almost like a tennis ball-like consistency.

Evan Brand: Yup.

Dr. Justin Marchegiani: But it’s still pretty firm.

Evan Brand: Yup, I understand.

Dr. Justin Marchegiani: So that’s kinda like the back— the back history on myself and my wife but when you’re looking at fertility, right, we look at a couple of things. Number one: How are the hormones, right? How are the hormones? Number two: How—how are the pipes, right? Are the fallopian tubes open? How’s the endometrial lining? Is it—is it okay for something to be able to, you know, implant there. And then number three: is we look at the dad.

Evan Brand: Exactly.

Dr. Justin Marchegiani: How’s the sperm count, motility, morphology. I was actually, really has no problem at that moment—that I was rock solid on all those numbers. So I felt very, very good about that.

Evan Brand: See that’s the problem, you know, You and I worked with so many— so many women. Primarily, men aren’t coming to us for fertility issues, but they have to come on board because it’s part of the equation. And a lot of these women that we speak with, the men, they just have a terrible diet. So we may put the mom or the future mom on AIP, but then the dad is still eating ice cream and pizza. And then they end up at the—in the—what do they call it, the vitro fertilization doctors, who want to spend what? 10-12-15 grand. But they may be unnecessary in most cases if we get the dad straightened out as well.

Dr. Justin Marchegiani:  Exactly. I mean, a lot of times, you know, what’s gonna affect the fertility is number one: having a nutrient poor diet; not having enough high-quality nutrients like zinc and arginine and healthy fats and proteins. And then also uhm— mitochondrial support coz sperm needs mitochondria to move or needs a healthy mitochondrial nutrients to be able to the kind of propel it, so to speak, right? So we have to make sure a lot of the good mitochondrial support there. And then we’re just not putting a bunch of toxins in there, right? Like we’re avoiding the plastics, we’re avoiding the pesticides, the chemicals, the round up, the glyphosate—all these compounds that are not gonna be so good for it.

Evan Brand: Yeah. The endocrine disruptors like you mentioned, like the plastic, so getting men and women off of Tupperware. I guess, by the way, if you haven’t figured out, this topic we’re— we’re talking about fertility today. Since Justin and I are both dads and our wives are both moms. This is a good topic for us. We’ve had first-hand experience on. So this is not theory and there’s also some science behind what we talk about. But that the endocrine disruptors that can cause things like the PCOS, which a lot of women that come to us, they’ve had PCOS. Previously are there—they’re trying to get help in reversing PCOS. That can be a huge, huge hormonal function disruptor that can affect fertility. So we’ve got to get rid of the the plastics. Plastic straws are a big one because your saliva, you know, my opinion, you’re breaking down that plastic a bit and you’re absorbing some of the— the phthalates in the plastic softeners when you’re chewing and using straws as toothpicks, that’s not a good one. Also, you’ve got flooring, too, like vinyl flooring. So if you’re walking barefoot on a vinyl floor, that’s typically gonna have phthalates in it. You’ve also got issues with the men as well. They’re just as susceptible to exposure to phthalates and other type of toxins. You mentioned pesticide so definitely going organic. If someone’s a mom, a lot of times women they’ve already had her first kid but they wanna have another kid and they are coming to you or I would see that a lot, too. You know,  I tell a lot of moms have got to stay away from a lot of the playgrounds because they use the rubber tires, the recycled tire playgrounds and those are very, very toxic and I’ve measured moms with the GPL tox chemical profile test from Great Plains and they’ve got the rubber toxins off the chart. And I say, “where are you playing?” And they say, “Oh, we go to one of those playgrounds with the recycled rubber tires” And that stuff is just super toxic or let’s say the mom has a kid who started sports, my God, I work with the woman last week who lived in London, and her child he was off the charts himself. So we haven’t tested mom yet, but we tested the kid coz we’re working more with him than her. And the kid was off the charts with 2,4-D— the agent orange chemical that they used in Vietnam. And I said you know, “Where are you guys playing?” And she goes, “Oh, he plays soccer” I said, “Is that football or soccer?” Coz she call it football. So is that football football or is that soccer?

Dr. Justin Marchegiani: Right.

Evan Brand: And so she’s on the field with this kid multiple times a week. In the field, just sprayed, I’m sure, pounds and pounds and pounds of glyphosate and 2,4-D

Dr. Justin Marchegiani: Yeah. I mean I kinda go back and forth, what’s worse, right, being on the artificial turf stuff or being on the grass? Coz you know the grass has given a whole bunch of chemicals, right?

Evan Brand: I Know.

Dr. Justin Marchegiani: So I—for me, and again, how many research? I’m just—a lot of what I do is common sense and based clinically.

Evan Brand: Yup.

Dr. Justin Marchegiani: Coz I probably rather be on the synthetic turf grass because at least you know it’s not being spray with round up.

Evan Brand: Yeah.

Dr. Justin Marchegiani: ..and pesticides all the time.

Evan Brand: I know. I don’t think they spray anything. One other thing about men, you know, when we’re talking about fertility for men, sperm quality. Heavy metals is huge. Mercola had an article about infertility where he was talking about how men are much more susceptible to issues in their fertility with heavy metals than eggs. So the eggs in the female were less affected by heavy metals and other pollutants than men. So that’s pretty interesting. A lot of guys have metal amalgams in their mouth. So we may— I’ve not personally had to go that far with any of my clients but what would you say? Would you say that could be a possible step? Does the man have to— may have to get a amalgam removal is done?

Dr. Justin Marchegiani: Yeah. I mean I think that’s definitely an option. If we’re seeing elevations in heavy metals—anytime I have someone a male with fertility issues, once the diet’s good and we’ve eliminated toxin exposure, then it’s about what nutrients can we add to enhance sperm quality, and then what things can we add to enhance detoxification.

Evan Brand: Right.

Dr. Justin Marchegiani: Maybe phase I or phase II detoxifying nutrients and maybe things to help push the heavy metal binding. So again, I’d wanna look at all that and if we’re seeing high levels of metals, and we know Mercury’s there, and then we’re seeing the person also the history of fillings— heavy metal fillings and then we wanna get that removed.

Evan Brand: Tapwater. Gotta have a good clean water that the person is drinking. We talked about the— the phthalates. So the xeno estrogens—coz that’s gonna affect the males.

Dr. Justin Marchegiani: Yeah. So if the male is more like a woman, you know, he’s got a lot of excess breast tissue and things like that, and we can assume, “okay you’ve probably got some estrogen problems” So just like you mentioned about females. Same thing for men, it could be an estrogen dominance problem.

Dr. Justin Marchegiani: Yeah. And we can look at that from two perspectives. I did a video called the “Hormone Switch” I recommend everyone to take a look at that. Will try to put links below for the “Hormone Switch” But when men’s blood sugar’s off, when they start moving into a direction of insulin resistance, they increase this enzyme called aromatase, which causes the hormone to switch. It will cause their testosterone to go more towards estrogen. And we see that quite frequently. And again, one of the best thing get one of the best thing you can do is put on more muscle. That will make you more insulin sensitive. A high intensity training type of regimen where you’re doing like a long, slow movement to get muscle activation or to get HGH, where you’re doing interval stuff. That’s gonna help significantly get the blood sugar under control and get the inflammation under control. A lot of these stuff, we always go back to the foundation coz we know there are people that are new that are listening every day so we don’t want to assume that the foundation is there. And all of our patients that listen, you know, listeners they get that. We kinda feel like a broken recored, but just to emphasize for new listeners.

Evan Brand: Yeah. We wanna get rid of dairy. I mean that’s gonna be huge on the diet piece. We’re talking about or talk about stabilizing blood sugar; we’re getting refined carbs out; were getting sugars out, but dairy, too. You know, depending on what piece of research you look at, that could be 60 to 70% of the estrogens consumed is coming from dairy, especially these cows that are not organic. So for us, the dairy is always gonna come out. Organic veggies are always good come in, organic fats, your nuts, your seeds, your vegetables. Unless the woman has some type of like Hashimoto’s problem which that can complicate things with fertility. Sometimes if there’s a thyroid issue, but let’s just assume that the person can do a good quality butter, can do some nuts, some seeds, maybe a little game meat even. That’d be cool. If we could get the mom eating some—some deer, or some type of game organ meats, or sardines.

Dr. Justin Marchegiani: Yeah.

Evan Brand:..or other home-cooked, home-sourced wild turkey, which we have ton of turkeys here. Those are awesome, too. Unfortunately, it doesn’t seem like local fish is an option here in Kentucky. I was reading the report by the Kentucky Department of Fish and Wildlife. They said that most of the fish are toxic here, unfortunately. With the— with high levels of mercury. So they set for people wanting to get pregnant or pregnant people should avoid the fish, which kinda sucks.

Dr. Justin Marchegiani: Yeah. Actually when it comes to the fish component, uhm—I have an article that I give my patients but really, it comes down to number one: trying to get the wild—you know, the wild Alaskan or like some kind of flash frozen, kinda wild fish, I think is great, is ideal. But it’s looking at the selenium to mercury ratio. Because fish are going to have a little bit mercury. The question is, “Is there enough selenium to combat it?” Because the selenium is the natural chelator of mercury. So just try to choose high selenium to mercury ratio fish. So skip Jack tuna. It’s gonna be the best type of fish off the bat uh—cod, haddock, sole, halibut. Those things are good. I have a good article in my member’s area for my patients. But if you just google like “high selenium to mercury ratio fish” you’ll get a nice list there.

Evan Brand: Uh—cool. I love cod, haddock. Those are awesome. I had something pulled up. I was trying to see I may have lost it, but just mentioning the link between food sensitivities and also miscarriages. Basically what happened is the link between having some type of allergenic reaction, you’ve got the cytokines that are basically suppressing the killer cells.

Dr. Justin Marchegiani: Yup.

Evan Brand: But when the immune system is off, the body can accidentally attack the egg. So basically, long story short, it sounds like just searching, investigating and finding out for food intolerances, which we’re gonna push most people into kind of a Paleo template as the starting place. Probably no grains, but at least no gluten, no dairy as a starting place. Will probably gonna rule a lot of those food intolerances out within the first month.

Dr. Justin Marchegiani: Yeah. Even push to autoimmune shtick as well. I know you kinda talk about a deer. That’s good when you’re doing autoimmune shtick, but I think adding at least back in the ghee and definitely the butter, as long as you can tolerate it, as long as like, there my patients are following the reintroduction protocol, which is adding the food back in over a three-day period. Gently increasing the amount as long as no negative reactions that’s fine coz you know, butter butyric acid’s a 1:6 uhm— carbon fatty acids. So it’s a medium chain triglycerides, so to speak, right? It’s very short chain length. It’s four carbons or six carbons, but it’s a really good fat; it’s a lot of nutrition, a lot of vitamin K which is really, really good for fertility uhm— so that’s uh—excellent fat as long as you can tolerate it, I think that’s great.

Evan Brand: And other bad things, too, like alcohol.

Dr. Justin Marchegiani:  Of course. Like alcohol number one: it’s a toxin. Again, in moderation maybe okay but number two: it gets metabolized to sugar. So if you have a little bit insulin resistance or blood sugar stuff, that can be a stressor. Again there’s ways to hack it by just using higher-quality alcohol and by timing it with protein and a little bit of fat uh—with your meals. It can slow down some of the absorption but you know, for a time period, if you have health issues, cutting it out for a month or two maybe a good idea to start with. And then choosing some of the drier, you know, white wines or drier champagne or Presecco or doing a really clean tequila or really clean vodka. Again, my Dr. J Moscow mules is one of my go-to’s  use with uh—Tito’s vodka and the ginger Kombucha and some lime. Or I just do a really good like Sean Don or like a really good brewed Presecco, very dry. I like the bubbles. Bubbles are uhm—you know the uh— the seltzer or like the CO2 carbonation. The bubbles are actually—there is actually research studies where they increase alcohol absorption with the bubbles. I was reading one study. I was like, “Damn, I love  to be in the study.” Like— you know, 15 years ago when I was in college, they were like, “ Yeah. We had a group of college kids and we gave one group alcohol and one group alcohol with you know carbonation and soda water.” I’m like, “that’s a great study for college.” Right? I know like, yeah, the group that got the carbonation with their alcohol uhm—you know, felt the effects, felt the intoxication effects or the buzz, you know, the so-called buzz effects sooner. So there’s some research with the carbonation in there helping to absorb the alcohol. So what does that mean, right? It means you’re a cheaper date.

Evan Brand: Yup.

Dr. Justin Marchegiani: You— less of it to get that same buzz, which means less toxicity on the liver. So that’s why like add the bubbles in there, that’s better. And you get that with my Dr. J Moscow Mule. Uh—you can do it as well with my Norcal margarita and we just you know, do a little bit of soda water in there when you can also do a really dry Sean Don or brewed Prosecco kinda drink there.

Evan Brand: Perfect. Let’s talk about IVF just for a minute. A lot of people and you know, the in vitro fertilization is like the first step if they are struggling. Diet, lifestyle, stopping smoking, which is insane. My wife had some friends that she’s not friends with them anymore because they’re just there were not good people overall. So we— we cut them out. They were too toxic in many ways.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Emotionally and physically, smoking cigarettes around her when she was pregnant, all sorts of crazy stuff. So we got rid of them.

Dr. Justin Marchegiani: It’s hard for someone to truly be emotionally balanced and healthy if they’re not physically healthy because the mind-body connection is just— it’s so strong, right?

Evan Brand: I know. Uhm—so anyway— but these people that used to be her friends.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: The guy, the dad, they were struggling with years. I think they were in their early 30s. They were struggling for years. They still do not have a child to this day. The guy was drinking beer almost every weekend, daily smoking of cigarettes, Mountain Dew’s. But yet they went to an in vitro fertilization doc and they were gonna spend 10 or 15,000 for the therapy.

Dr. Justin Marchegiani: Yeah.

Evan Brand: It’s just insane. You’re not addressing the root cause.

Dr. Justin Marchegiani: No, you’re not. I mean, typically the first, you know, thing they’re going to do is they’re gonna do some kind of Clomid or FSH stimulating drug. The core goal of that is to increase the eggs, increasing amount of eggs, right? So they’ll do like Clomiphene Citrate or some kinda Clomid and then depending on sperm quality. If the sperm count is low, they may do IUI which is like intrauterine insemination kinda fancy turkey baster.

Evan Brand: Yeah.

Dr. Justin Marchegiani: The sperm up and they may wash it and stuff and pick the best ones and then they’ll inject it right into the uterus. So then there’s no journey of these guys have to— the sperm cells have to make to get up there, right? Coz if they’re a little bit more mitochondrial depleted, or they don’t have good mor—motility, like they’re not moving in the right direction or their shapes not good. They may not be able to make the journey. So the whole idea is to use that uhm—artificial turkey baster. You can get it right there, so their journey is shorter, right? You’re cutting their journey down by 80% and then they’re stimulating the heck out of the eggs. That’s the first step. And the next step is full IVF which is they’re basically giving you drugs like Lupron to shut down your HP AG access, you know, your hypothalamus pituitary axis, And they’re gonna give drugs to stimulate FSH. Uh—they’re gonna give drugs to then manipulate ovulation. And then they’ll probably give some kind of uh—progesterone afterwards to help hold the implantation of the egg. That’s pretty much the cookbook. There are new medication that comes in—Gonal-F, Follistim, Lupron. All these different drugs may be used uhm—but the goal is kinda the same— stimulate, you know, egg production, enhance ovulation, help hold onto uhm— progesterone levels so the eggs stick better.

Evan Brand: Well, I remember seeing a picture. I think it’s a picture of my wife that showed me where this couple had had hundreds of vials— like an entire couch or an entire floor full of vials that were daily injections, I believe, for that whole process. Which this is one: it’s expensive; two: that just doesn’t sound very fun; and three: in a lot of cases, I don’t have any numbers. I’m not gonna make up a number on the spot, but in so many cases, if you just address diet, lifestyle infections, thyroid health, adrenal health, you’re doing the fatty acids like you talked about, the collagens, your zincs and selenium’s, and your natural folate’s, and your vitamin C, and your omega-3’s, it’s like that’s a prescription that’s gonna have far higher success rate and it’s gonna be virtually free because you have to eat to survive. So you’re going to be eating all these good things, anyway.

Dr. Justin Marchegiani: Totally. And we do things like chase tree and tribulus to modulate LH and FSH. So like that will modulate FSH; the tribulus will modulate LH with chase tree. And these are things that help talk—help the brain talk to the end gonads, you know and create stimulate the follicle or help the progesterone, right? So will do that with some herbs. We can always c_  augmentation protocol where we put estrogen—I’m sorry—progesterones in there, right? at certain times of the cycle, day 15-27. We can even add in some uterine supporting herbs like maca, m__, dong quia, alpha alpha, raspberry leaf extract. These are great uterine tonic herbs that really help the blood flow get to the uterus which is good because that uterus— these adequate blood flow to help support that egg when it sticks. So I tell patients think of progesterone as a sticky glue that helps the egg hold, but we need good uterine flow. That’s why my wife and I had a hard time getting pregnant at first because we have this fibroid that was sucking a lot of the angiogenesis out, right, the angiogenesis’ blood flow. So it’s creating a lot of blood flow to the fibroid and not to whatever else was gonna stick there i.e. the egg.

Evan Brand: So did you all have to do herbs? Or did you do herbs or just the diet lifestyle is all you needed?

Dr. Justin Marchegiani: Uh—we had herbs going in the background the whole time.

Evan Brand: Okay.

Dr. Justin Marchegiani: Yeah. We had that the whole time there and uhm— a little bit of progesterone going as well. And again, we just— I measured it, like I want 15 or higher, 20 is ideal. So Iike after she got pregnant, we measured progesterone. We make sure it was adequate. And it was, so we pulled off it.

Evan Brand: And what were you doing? Like drops or—

Dr. Justin Marchegiani: Progesterone drops. Yup. Exactly. So, like typically like a 100 mg is a good starting point once you get pregnant. And again, we just monitor it and it just kept on rocking. And again, if the ACG is high enough, typically the progesterone will be high enough because the hCG is uhm—gonna be produced by you know the follicle and also the placenta will kick in and produce it as well. And that hCG will then jack up the progesterone, too.

Evan Brand: Oh, that’s cool. all that’s cool okay you didn’t you didn’t have to continue, you’re saying?

Dr. Justin Marchegiani: Correct. You know, we didn’t have to. But some women who have lower progesterone, they may have to keep that progesterone going for the first trimester.

Evan Brand: Now is that something you have to get via prescription or are there over-the-counter natural ones you can get?

Dr. Justin Marchegiani: It depends. I mean, I typically give my sublingual one until I can get the fertility OB to write one, just more from a legal standpoint. I rather have the OB write about identical prescription just so, you know, if they’re working with that person that we know it’s covered. But the protocol is gonna be the same and typically will do like an intervaginal uhm— progesterone just so we know it’s getting right to the tissue. It’s—it’s— it’s being released closest to the tissues. So will do that. If we have an option, some OBs that they won’t do it uhm— just because they’re not looking at the progesterone or because a woman doesn’t have a—a history of miscarriage. They’re not gonna even look at it. But I mean, do you really wanna go through a miscarriage then know your at risk to then wait to the next time to do it?

Evan Brand: No joke. Right.

Dr. Justin Marchegiani: Yeah. I rather be monitoring it. And you know, if it’s below 15 or you know, I’m gonna be supplementing with some progesterone to make sure their support there. You can’t go wrong with it. Just make sure you’re using the good-quality progesterone. And again, we’re giving a lot of clinical advice here. And there maybe a lot of people that are just lay people listening. I don’t recommend doing this by yourself if you really want to work with the provider that’s done this a lot, so uhm— you know what’s going on and you wanna have everything looked at. So you want to make sure that we’re supporting the adrenals. Typically when someone’s pregnant, the only thing I’ll keep them on are nutrition, nutrients, whether it’s vitamins, minerals, amino. I’ll typically keep them on probiotics, I’ll keep them on digestive support, HCL enzymes and the only hormone I’ll typically keep them on, when they are pregnant, if it’s necessary “necessary” is the progesterone.

Evan Brand: Yup. Well said. Well that’s the thing. We love talking about adaptogens so much but nobody’s gonna do the research on rhodiola or these other herbs and how they could impact the fetus. So we just, you know, we love those things but we just can’t safely recommend them because we just don’t know.

Dr. Justin Marchegiani:  It’s probably safe, but again, like, think about it, who’s gonna sign up for that study?

Evan Brand: I know.

Dr. Justin Marchegiani: Right. Whose gonna sign up? “Hey, by the way, congrats! You’re pregnant. Hey we’d love to have you sign up for this study where we test these adaptogenic herbs on health and viability”  “Uh—no, I’m good.

Evan Brand: Right. So I mean—some of it we can draw from—from ancient peoples what they’ve used. Like you mentioned the chase tree which has been used in extreme long time. So a lot of it, we’ve probably already lost due to just modern life. We’ve lost touch with our hunter-gatherers, what herbs and plants and trees and stuff that they use during pregnancy, unfortunately. But like you said, diet lifestyle, foundations, HCL, enzymes, probiotics, fish oils, vitamin D. Did you hit— did you mention that one?

Dr. Justin Marchegiani: We did not. But vitamin D is definitely important. We have to have to look at potentially even give my baby a little bit extra. I was speaking to one of the in the neonatal uhm— docs there and he was telling me you know, you may want to give your child an additional above and beyond what’s in the breast milk 400IU sublingually uhm— for the baby. So we’re looking at getting some extra bit of that, but, you know, we’re gonna weigh it out. If we can get the kid out there at 8 AM in the morning 15 minutes out in the sun at 8 AM that may be enough, right?  We don’t even need the drops.

Evan Brand: Yeah. What the—lady we spoke with said. She said as long as my wife was getting 6 to 8000 units that which I think this is just probably her making up numbers on the spot but she said that if my wife were supplementing with 68,000 units daily that the baby would probably end up getting at least 500 to 1000 units from that that would pass through.

Dr. Justin Marchegiani: I think that, too. I asked that and they were like, well you should still give it. But it’s probably like a CYA comment.

Evan Brand: Exactly.

Dr. Justin Marchegiani: You don’t know exactly, but I think if she’s getting 6 to 10,000 the day, I think you’re gonna get 5% transfer to the—the baby in the breast milk.

Evan Brand: I guarantee it.

Dr. Justin Marchegiani: I think it’s probably good. So we’re probably gonna make sure she just getting 10,000 a day with the K2 and just get the kid out in the sun a couple times a week in those early morning hours and you know, just enough to give him a little sun kiss. Nothing else.

Evan Brand: Yup. Do you wanna talk about lab test for a couple minutes and just talk about what we would recommend someone get if before they even think about conceiving. You know, we kinda talk about pregnancy and birth and delivery and all that, but really, it begins far before that. So you and I kind of talk a bit like a five or six trimester is really what pregnancy is coz you gotta do the preparation then the postnatal care is important, too. So vitamin D—we hit on that. As a blood panel, insulin or blood sugar if you knew you, had a history, you could get the stuff done. Uh—fasting insulin.

Dr. Justin Marchegiani: The fasting insulin’s great. We want less than seven, ideally, less than five. We may even want to just do some functional glucose tolerance testing, i.e. just testing your blood sugar with a blood sugar meter. Fasting one hour, two hour, three hours after a meal. Choose a couple of different meals a couple times a week, breakfast, lunch and dinner. Some people we hire in the morning coz of the somogyi effect which is totally cortisol driven. So you’ve gotta keep that in mind.

Evan Brand: Yup.

Dr. Justin Marchegiani: And uhm–  I would say, we’re gonna do an adrenal test, for sure. And we may just do a female hormone test around day 20. We’re looking at estrogens and progesterones and such and testosterone, but if there’s a more of a fertility history there, we may run was called the “month-long test” or on the 209 panel from Bio health which is a month-long panel. Will look at progesterone level starting at day 2 every other day in the cycle.

Evan Brand: Thyroid markers. I’m gonna look for antibodies, your TPO, your TG antibodies..

Dr. Justin Marchegiani: Yeah.

Evan Brand: To see if there’s autoimmune going on.

Dr. Justin Marchegiani: Yeah. If there’s some history going on, or symptoms, will definitely do it, but you know, TSH, T4,T3 antibodies, reverse T3’s is great. And you know, one of the things that I give my wife during pregnancy is a couple hundred extra micrograms of iodine a day. There’s some good research about helping the babies IQ. So we did a little bit of that.

Evan Brand: You can have a genius baby now.

Dr. Justin Marchegiani:  Now the goal is to give the kid all of the all the resources it possibly can, right? That’s the goal of you know, being a great mom and great dad is giving your kid as much potential as possible. And a lot of that’s gonna be uhm— healthy pregnancy, right? Healthy nutrition, healthy prenatal nutrition.

So healthy fats, healthy protein, healthy carbs, nutrient density has to be high, inflammation has to be low and uhm— making sure there’s enough calories and good macros. And we’re going a little bit higher on the carbs right now. But this is true when you eat for two.

Evan Brand: A 100% man. Tell me, my wife, she— she ate way more than me and she still—she actually weighs now than she did before she got pregnant which is interesting. I mean—

Dr. Justin Marchegiani: It’s a great benefit in breast feeding.

Evan Brand: It’s definitely depleting, though. It can be depleting, so we’re doing our best to keep her— to keep her full and—and satiated.

Dr. Justin Marchegiani: Yeah. We also did placenta encapsulation as well.

Evan Brand: Oh, sweet man. Yup. Cool.

Dr. Justin Marchegiani: I actually have pictures of a placenta. It’s pretty cool.

Evan Brand: I planted my wife’s with a tree.

Dr. Justin Marchegiani: Really? Wow!

Evan Brand: A little tree sprout, a little maple tree sprout at our old house. I had the placenta coz we’re going to do encapsulation. We had a doula that’s gonna do it for us, so we decided—she felt so good postnatally that she didn’t need it. And—and so I had the placenta in the freezer, took it out so I could actually mold at first, you know, mold it a little bit and dug uh— dug a giant hole, buried it couple feet under with the— with the little maple sapling right there. So there should be a tree there one day.

Dr. Justin Marchegiani: Wow! That’s amazing. So we had it encapsulated, so she’s doing three capsules 3 to 4 times a day. And then we have uhm—we actually had a  tincture made, too, which is pretty cool.

Evan Brand: A placenta tincture?

Dr. Justin Marchegiani:  Yeah. And we’re gonna save that for menopause for her.

Evan Brand: Really?

Dr. Justin Marchegiani: When she transition to menopause, we’ll use that tincture.

Evan Brand: That’s a thrift.

Dr. Justin Marchegiani: Yeah. Isn’t that cool?

Evan Brand: I did not know that. So what’s—what’s the idea there? There’s gonna some naturally occurring hormones in the placenta that will help to ease menopausal symptoms?

Dr. Justin Marchegiani:  Exactly.

Evan Brand: Ahh—Okay. We’ve got uhm—we’ve got a couple questions. I think they may not be related to our topic because our topic’s pretty niche today. But do you want to look at these questions here?

Dr. Justin Marchegiani: Yeah. We try to grab the ones that are most relevant for sure.

Evan Brand: Okay. There was a person named, Chris here, that said he was diagnosed with Hashimoto’s and is displaying signs of hypoglycemia with perfect blood sugar, what could it be? That’s gonna be a good question. Do you get that question?

Dr. Justin Marchegiani: Yeah. So his blood sugar may look good but why does it look good, right? The question is— are the adrenals coming to the rescue to make that

Evan Brand: Uh-hmm.

Dr. Justin Marchegiani: Coz if the adrenals are coming to the rescue and lifting that blood sugar up, there’s gonna be a lot of cortisol and adrenaline in the background which are gonna create a lot of anxiety, and mood issues, and irritability, and a lot of things where your blood sugar may look good, but the question is, what’s lifting that blood sugar up? Ideally, we want healthy blood sugar by diet, meal timing, nutritional density so the blood sugar is lifted up naturally not relying on the adrenals to keep it lifted.

Evan Brand: Yeah. With the adrenals are kind of the backup generators of the adrenals are getting involved with your blood sugar regulation, that’s not good. That means something else is off elsewhere, but if the diagnosis of Hashimoto’s is there, too, could we say that if—if there signs of hypoglycemia maybe it’s not hypoglycemia, maybe it’s thyroid as well because I mean the thyroid can make you feel like your fatigued and lethargy and then all of a sudden, you’re over stimulated.

Dr. Justin Marchegiani: Totally. If you have hyp—If you have Hashimoto’s there’s probably potentially some T4 to T3 conversion issues.

Evan Brand: Yeah.

Dr. Justin Marchegiani: And there’s probably some adrenal issues so all that stuff needs to be looked at and then again, we don’t even know where that— this person is in the hierarchy of diet and lifestyle.

Evan Brand: Right.

Dr. Justin Marchegiani: So we’re assuming that diet and lifestyles are already even adjusted. 30 g of protein in the first waking, eating— eating healthy proteins, fats and the right amount occurs every 4-5 hours or assuming that that’s already dialed in.

Evan Brand: In preferably on an AIP approach and until the antibodies are very, very minimal in the single digits or less.

Dr. Justin Marchegiani: Yeah. If possible, I typically wait till there’s a there’s plateauing of uh symptoms. Some people may not be able to get them all the way low but you know, we at least want to get them under 500 or so. It depends. If we could get  someone under 500, that’s a pretty good reduction.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Again—

Evan Brand: What’s the highest you’ve seen with TPO? I think the highest I’ve seen was like 1600 on a TPO.

Dr. Justin Marchegiani: I’ve seen over 2000. I mean I have patients literally go from over 2000 to under hundred.

Evan Brand: Yup. What’s the timeline? A year?

Dr. Justin Marchegiani:  I’ve seen it happen in six months to a year.

Evan Brand: Yup.

Dr. Justin Marchegiani: Yup. The average person that I work with, we have at least a 50% reduction in antibodies.

Evan Brand: Right. That’s awesome. I love seen that on a piece of paper. When you actually get to validate it, but then their symptoms are better, too. It’s such a double win.

Dr. Justin Marchegiani: Oh and I had so many patients say their endocrinologist just says, “there’s nothing you can do about that”

Evan Brand: No.

Dr. Justin Marchegiani: And it’s like over and over again, and we just continue to prove them wrong and it’s just like, “man!”

Evan Brand: It’s a great feeling.

Dr. Justin Marchegiani: I feel so bad. It’s just like, you know, imagine having someone like, you know, hiring someone to fix your house and all they have is just a hammer. It’s like, “dude, you’re missing the saw and the screwdriver, this and everything” It’s like functional medicine is that we get so many tools at our disposal. We’re not limited to just like that one pharmaceutical tool that’s supposed to be in our toolbox, right?

Evan Brand: Yup. Well the same thing with fertility question. I mean, you and I have  talked to dozens and dozens of men and women who’ve been told that they will never be able to have children, yet we’ve aided, and many, many babies, you know, just being made by helping women get their hormones back on line and fixing the underlying issues, so—

Dr. Justin Marchegiani: That’s it, man. I 100% agree. So, I hope that helps there. Anything else we can grab before__

Evan Brand: Yeah. Let’s see what we have here. That was unrelated questions—

Dr. Justin Marchegiani: Someone was asking about Probio Flora and Sacro Flora. And again, those are some of my probiotic products. Sacro Flora is a high-dose saccharomycin, Probio Flora is a high-dose bifido-lactobacillus uhm—probiotic. We typically do that for at least 60 days after a parasite killing protocol.

Evan Brand: Here’s a good— here’s a good question here from Naomi. She said she’s been diagnosed with blastocystis hominis, which for those listening, that’s a common parasite infection we see. She’s exclusively breast-feeding a six-month-old and the antibiotic metronidazole did not seem to work. “Is it possible to treat while still feeding baby?

Dr. Justin Marchegiani: The only way I would treat it is with probiotics right now. I would not do any herbs. I would choose two probiotics. I would do Saccharomyces and high-dose probiotics that’s the only thing I would do right now to treat it.

Evan Brand: Yup. So, Naomi, when the time comes for you to wean off the baby which if it six months this may be another year or so, we don’t know how long you intend to breast-feed, at that time, reach back out to us. Justin and myself we can help you get rid of the blasto using herbs but, yeah, with these anti-parasitic herbs, we—we just— it’s just not—not a safe. Well it might be safe, but we just don’t know. We don’t know if that’s—

Dr. Justin Marchegiani:  It probably would be safe, but we don’t want a chance and we rather be just conservative, right? Always do no harm. So I feel very comfortable recommending probiotics. There’s been studies done on kiddos, actually, looking at Saccharomyces polarity uh—compared to Flagyl Metronidazole Tri and Blasto, and it’s just as good, if not better.

Evan Brand: Yup. So look it up, Saccharomyces polarity. Check out Justin’s, we both got Saccharomyces polarity products. There’s a lot of good ones out there. Just make sure you get professional grade, so that actually works.

Dr. Justin Marchegiani: Exactly.

Evan Brand: Cool. Yeah, I think that’s it, man. We can wrap it up. Will send people back to your site if you wanna learn more about you or work wit you.  myself,  Check us out. We’ve got hundreds and hundreds of episodes. So if we just hit the surface of one piece of the conversation you like today, then I’m sure we dove deep somewhere else and give us a review. I know you may be watching elsewhere, YouTube, Facebook etc. but iTunes is where it counts. So we need to continue to beat out people like Jillian Michaels who promotes just not sound advice and so we wanna really bring functional medicine to the forefront of humanity and help to save some of the crises that are going on in terms of depression, anxiety, infertility, obesity diabetes, cancer. We want to put a dent in the universe. So give us a review so that we can do that and stay in the top of the charts.

Dr. Justin Marchegiani:  Awesome! And you guys, subscribe right now, my YouTube,; Evan’s YouTube. Uh— click on our YouTube link. We appreciate the subscriptions, care—you know, sharing is caring. We love it. And again, give us feedback. We want feedback about what you guys want to hear because this is all about how we can serve you guys better. So let us know so we can provide more awesome information. And again, what makes us different Evan I different is, we keep it real. You’re gonna walk away from our show and our podcast with actionable item not esoteric BS that’d gonna make sense you up in the ether, right? But what can you actually do. So that’s how we’re different. We’re trying to keep it real and make it actionable for you guys. So we appreciate you listening. And everyone have a great day.

Evan Brand: Take care.



Estrogen dominance – Podcast #110

Dr. Justin Marchegiani and Evan Brand talk about hormones, their importance and their functions, as well as the symptoms of hormonal imbalance and what causes estrogen dominance. Understanding hormones doesn’t have to be complicated and if you listen to this podcast, you’ll get a clearer picture of what hormones really are and particularly for women. 

estrogen dominance - hormonal imbalanceFind out having balanced hormones is the key to feeling good and having energy. Learn how to avoid any imbalance and how to fix these issues to help you overcome stress. Discover what you can do and gain indispensable knowledge about dealing with hormones especially for females so you can perform at your best and be in optimal function.

In this episode, topics include:

00:42   Hormones

04:30   Symptoms of estrogen dominance

08:13   Causes of estrogen dominance

17:22   Phytoestrogens, stress allocation and avoidance

25:20   Nutrients










Evan Brand:  Dr. J! How’s it going?

Dr. Justin Marchegiani:  Evan, it’s doing great, man! How you doin’?

Evan Brand:  Pretty—pretty well. I’m glad we got this internet thing straightened out. Let’s hit this estrogen dominance topic. People have been asking via email, social media. Clients of ours have been asking about hormones and trying to understand them. There’s so many things in the environment that impact them. Your lifestyle, your diet can impact those and so you and I wanted to outline all this together and talk about what’s affecting your hormones, why is it so complicated in the modern world, what are the new variables that didn’t exist and then what do we do to fix it. So do you wanna start—start us off?

Dr. Justin Marchegiani:  Yeah, so hormones are interesting, right? Hormones are these messengers, right? They help with inflammation. They help with growth mediation, i.e., healing and recovering, putting on muscle. They help with reproduction. Not only reproduction like in reproducing ourselves so we heal but also having children and healthy hormone balance is essential to us feeling good, to us having energy, to us being resilient and vital as we—as we age and deal with stressful situation. So hormone balance is really, really important. Now as women—women have 2 different kinds of hormones that are constantly in fluctuation generally speaking, right? Men are kind of this foghorn of hormones throughout the month. Again there’s some fluctuations on a daily basis with cortisol, as are women, but on a monthly basis, you know, men kinda have this flat rhythm regarding testosterone. Women have this kind of symphony of hormonal fluctuations regarding estrogen and progesterone. And I tell my patients estrogen is the hormone that makes you grow. Progesterone is the hormone that makes you grow up. Meaning estrogen just causes cells to just grow bigger, while progesterone helps cells to differentiate and mature, okay? This is important so throughout your cycle, kinda breaking down a woman’s monthly cycle I think is really important for the first place of connecting the dots of where abnormalities happen. So first off, women’s cycle begins with bleeding, with menstruation. Typically about 3-4 days, maybe 5 days long in some extenuating circumstances. That happens because of a drop in progesterone and estrogen. So progesterone and estrogen drop, that signals bleeding. So the uterine lining is now shed over that 3 to 5-day period. The next thing is the follicle starts to grow and that follicle, FSH from the brain is starting to be produced and that causes the follicle to grow. So FSH talks to the follicle, the follicle starts to grow. As the follicle grows, estrogen is produced by the follicle. That’s step 3. As estrogen is being produced, it eventually hits a—a toppling, you know, where it hits its highest level around day 6-9 or 6-10. Then progesterone starts to increase as estrogen tops out, alright? Progesterone is increasing due to LH. LH is luteinizing hormone. That’s a brain hormone. The two brain hormones are FSH and LH. As progesterone topples out around day 20-23 or so, that’s where hormones are at its highest regarding progesterone and then day 27-28, progesterone and estrogen fall. So if we kinda recap it real quick, briefly what’s happening is we have brain hormones causing the follicle to grow. The follicle stimulating estrogen. Estrogen stimulating LH, LH stimulating progesterone. Progesterone and estrogen dropping. And that’s kinda the general dr—gist of the average female cycle, right around 28 days or so, and about day 13-15 is where ovulation happens. That’s right where estrogen tops out and progesterone starts to rise. That’s where that 2-3 window of pregnancy happens. I’ll just take a breath and give you a chance to break it down, Evan.

Evan Brand:  Sure, sure, makes perfect sense. And a lot of women that you and I are working with may be perimenopause or menopausal so we can talk about the ebb and flow and things that change there. So basically as you’ve kinda alluded throughout most of the reproductive years, the estrogen and progesterone are in a pretty good balance, but then if you look at all the information with progesterone and estrogen levels changing, then it looks like the gap becomes bigger where there’s a relatively high estrogen compared to progesterone and that’s what we would call menopause, and then that’s when these symptoms can start to occur. So I guess what I should do now is just go through some of these what consider estrogen dominant symptoms. So this could be allergies. This could be breast tenderness. You have copper–

Dr. Justin Marchegiani:  yeah.

Evan Brand:  Excess.

Dr. Justin Marchegiani:  Uh-hmm.

Evan Brand:  Which I did a video on copper toxicity and everybody’s like blown away by the idea of too much copper. How about cold hands and cold feet? Decreased sex drive, depression with possibly some anxiety or agitation added to it. Could be dry eyes, fat gains especially around the abdomen, the hips, the thighs, fatigue. Could be brain fog, which sometimes that could be yeast-related as well. Hair loss, headaches, blood sugar issues and fertility, irregular periods. You and I have talked about amenorrhea, just missing your period completely before. Irritability, insomnia, mood swings. I could go on and on. I think that’s a pretty good handful of symptoms though.

Dr. Justin Marchegiani:  Yeah, absolutely. So when estrogen’s out of whack, a whole bunch of symptoms happen. The real common ones like you mentioned—most females—these are the ones that I deal with on a daily basis with all my patients, you know, the big complaints. It’s gonna be moodiness. It’s gonna be breast tenderness. It’s gonna be cramping. It’s gonna be back pain. It’s gonna be migraines, moody, sweet cravings or sugar cravings, and I would say like water retention and even weight gain.

Evan Brand:  Yeah, I would say the sex drive one has been something big. I ask that question on my intake, you know. Do you think your libido adequate? And it’s very, very rare to find a women over age 40 who says that her libido is adequate. You know, some women said they haven’t had a libido in 20 years. So I mean, these things can change with hormones and they’re not just gonna magically fall into place by diet and exercise. So eventually you and I are gonna outline what exactly is going on in the external environment that is throwing off this whole hormonal cascade here.

Dr. Justin Marchegiani:  Exactly and typically, as a women ages, menopause is nothing more than the ovaries not functioning like they were when you were cycling and you have a drop in hormones from that. Typically over time, one the big things we see with hormonal—hormonal fluctuations over time is that estrogen drops at about 35% the rate from age 35 to 50, while progesterone can drop at 75% the rate. So this whole podcast is really surrounding the topic of estrogen dominance and part of estrogen dominance is just being exposed to a high amount estrogens in the environment—that we’ll go into in a second. The other half is is progesterone being essentially dropping so fast that estrogen—the ratio of estrogen goes above and beyond what would be normal essentially.

Evan Brand:  Right.

Dr. Justin Marchegiani:  So if progesterone starts to drop faster than estrogen, even though you may have more progesterone as a basic flat line number, that’s still gonna be estrogen dominance. I mean, some people say over the course of a whole cycle you’ll have 300 times more progesterone than estrogen. At certain times of the cycle, like depending on where you’re at like let’s say, in the follicular phase you may have as many—as much as 25 times more progesterone to estrogen. So it’s different from the perspective of where you are in your cycle, but in general estrogen and progesterone—progesterone will be about 25 to 300 times more in relationship to estrogen, alright? So if that skew starts to get disrupted and we start to have less progesterone, let’s say below 20, you know, below 15 on average, that may be a big driving factor of estrogen dominance and a lot of the whole PMS symptoms and the symptoms that you just mentioned as well—the brain fog, the libido, dry hair, dry skin, dry nails, cold hand, cold feet, cramping, breast tenderness, all the things we already mentioned.

Evan Brand:  And let’s talk about some of the causes here. Birth control being a big one that can contribute because with birth control, you’re basically just keeping your estrogen levels sky high and so this is just a common prescription for many teenage girls, I’ve heard of even girls as young as 12 years old now getting put on birth control pills for their periods, you know, if they’re having really bad periods. So talk us through that. What’s going on with birth control pills? Why are these such an issue?

Dr. Justin Marchegiani:  Well, birth control pills are nothing more than like synthetic estrogens. You have like Yasmin and these synthetic estradiol compounds and they basically jack up your estrogen level as a female about 4 to 500%, 4 to 5 times. And that’s a problem because hormones, right? If you look at—go to any opera or any symphony, there’s a specific timing and a volume in which everything needs to operate in. If something goes too—too loud or too quiet or something, the timing’s off, you can easily have a beautiful symphony turn into noise pretty darn fast. Now taking that analogy to a hormone cycle, if those things start to go too high because of synthetic hormone overload or too low because of hormone stress driven by inflammation, that can start to create hormonal symptoms. So that’s the big thing right there off the bat. So estrogens are gonna be jacked up way high. Sometimes with the Merena IUD, that’s inter—interuterine compound that’s put up there to prevent the egg from implanting in the uterus lining, that is—that’s actually using synthetic progesterone. So that’s a little bit different. But most of the birth control pills are gonna be synthetic estrogen-based and basically what it’s doing is keeping the estrogen so high all the time so you don’t have that rise in progesterone happening. You don’t have that cycling of hormones. So basically it shuts the HPA axis and because your hormones are so high, the LH and FSH kinda go to sleep because–

Evan Brand:  So the body eats—the body thinks it’s pregnant.

Dr. Justin Marchegiani:  Well, not necessarily. The body—well, I guess you could say at a certain level. Typically progesterone’s gonna be really high with pregnancy and you’re gonna have HCG off the chart. So you’re not gonna see that because if you ran a pregnancy test while you were on a birth control pill, you wouldn’t come back with a pregnancy test being positive because you’re not making–

Evan Brand:  Right.

Dr. Justin Marchegiani:  The beta HCG. But what it’s doing, it’s shutting down the brain because the brain has this domino rally of FSH raising and then LH raising, so kinda shuts that down, because when the hormones are really high, FSH and LH don’t really have to work as much because the high amount of hormones is just shutting down the whole entire symphony. It’s like going into a symphony and with the foghorn. You just overpower all the instruments, you just can’t hear anything.

Evan Brand:  Makes perfect sense. Let’s talk about the metabolism of these two. That’s something that people do not talk about. There are side-effects that we could go into. We won’t bore you with those today, but there are nutrients—your vitamin C, your magnesium, zinc, and other minerals that are required for metabolizing these pills through your liver. So if you look at someone who has been on birth control for many, many years, mo—more than likely you and I are gonna look at their adrenals. We’ll probably see low function and if we look at like an organic acids test and if we’re looking for vitamin C or other nutritional markers, they’re probably gonna be deficient. Maybe not a—maybe not the only cause would be birth control but it’s definitely a factor. And then now I know we have to mention the environmental part of estrogen still. You know, we’ve talked about adding excess estrogen in via birth control but we have all the xenoestrogens in the environment, and now we’re seeing teenage boys with man boobs and you know, this is not—this is not good. This is not something that would have happened let’s say even 100, maybe 150 years ago with this breast enlargement. Can—can we go through some of those like the, you know, the—the meats, the plastics, the canned goods, all of that stuff?

Dr. Justin Marchegiani:  Yeah, exactly. So again, we already kinda mentioned some of the mild to moderate symptoms regarding estrogen dominance and again people that are listening that are familiar with some of the pathological situations like uterine fibroids, endometriosis, fibrocystic breast, polycystic ovarian syndrome, even breast tumors. Those are ultimate, you know, severe more pathological forms of estrogen dominance in action.

Evan Brand:  Right. It makes sense.

Dr. Justin Marchegiani:  And then—yeah, and regarding some of the underlying environmental causes, too much sugar is gonna drive a lot of this because too much sugar is gonna increase insulin. Insulin resistance drives more fat growth. Because if our cells are saturated and we can’t burn sugar in our muscles, well, guess what happens to that sugar? It goes right into fat and fat actually is its own exocrine gland. It produces a hormone that’s gonna cause fats—it’s gonna basically produce leptin which is another hormone that’s gonna decrease our body’s ability to signal satiation and signal that we’re full, which is another thing, and it’s also gonna produce more sex hormones like estrogen. So if we have more fat cells, fat cells will actually produce more hormones and throw us off even more. So driving insulin resistance, driving fat, fat will then drive more estrogen and then also it’s gonna screw up the whole combination here with leptin which is gonna make us feel hungrier and eat more of that same junk that got us there and to begin with. So a lot of these mechanisms that we overlay, you can see there’s almost like this vicious cycle to them where they kinda repeat itself on a loop over and over and over again.

Evan Brand:  Yeah, and then like you mentioned, they could all start with diet or sugar. So I mean, that’s a—that’s a huge one. It’s not something that we wanna skip over but you and I, we hit the diet piece so much that we’re assuming if you’re listening to this show, then you’re generally closer to like an AIP style diet where you’re not eating gluten. Maybe you’re doing a little bit of dairy in the form of like some ghee or some grass-fed butter.

Dr. Justin Marchegiani:  Right.

Evan Brand:  But beyond that, you—you gotta have that foundation in place, and then we could go on with the personal care products. You got your pesticides and herbicides.

Dr. Justin Marchegiani:  yes.

Evan Brand:  But you’re eating organic, you’re avoiding that. You got your makeup for women. So that—that is in the personal care category.

Dr. Justin Marchegiani:  Huge.

Evan Brand:  But think about women that are lathering themselves a lot of times with heavy metals and phthalates and all that, too, in their makeups.

Dr. Justin Marchegiani:  You also have your pesticides, I mean, a lot of those are estrogenic in origin. Pesticides, fungicides, herbicides. You have a lot of chemicals in the water as well. Remember when you get your water filtered back, the conventional water filtration in your community won’t filter out a lot of the hormones in the water. So you’re getting–

Evan Brand:  Yeah, we—oh yeah.

Dr. Justin Marchegiani:  Yeah.

Evan Brand:  The—the trace amounts of pharmaceuticals you’re talking about–

Dr. Justin Marchegiani:  Yeah.

Evan Brand:  That people flush down the toilet.

Dr. Justin Marchegiani:  Uh-hmm. Absolutely.

Evan Brand:  Fluoride would be another one that we could talk about.

Dr. Justin Marchegiani:  Yup.

Evan Brand:  That’s another endocrine disruptor there.

Dr. Justin Marchegiani:  Yeah, fluoride. Also a lot of these polybrominated diphenyl ethers that are in flame-retardant products and various solvents, definitely not good. Milk if we’re drinking or consuming conventional dairy, a lot of the milks are treated with a Posilac, which is—or similar—no, Similac’s the formula. Yeah.

Evan Brand:  Right.

Dr. Justin Marchegiani:  It’s Posilac. Posilac is the growth hormone given to cows to produce more milk essentially and then we have conventional dairy or conventional meat which could come from cows because cows are gonna be given hormones as well on the meat side, right? You have your Jersey cows which produce the milk. They’re given the Posilac to make more breast milk or make more you know, cow milk, and then we have the cows that are eaten for steaks and meat and those cows are gonna be given more growth hormone and estrogens to make more meat as well. They’re also given mycotoxins, too, to produce more fat to make their meat more marble then they’re given a lot of grains which are loaded with mycotoxins as well to make the meat more marbled. So a lot of different chemical toxins that are coming in on both sides of the fence.

Evan Brand:  Yeah, not even to mention the grain they’re getting fed is likely sprayed with glyphosate or it’s genetically modified grain that these conventional meat products have consumed.

Dr. Justin Marchegiani:  Bingo. Exactly.

Evan Brand:  Yeah. Last thing on—on the, I guess on the xenoestrogen route would be fragrances. So any woman or man wearing you know, perfumes, colognes, air fresheners, using those little trees that people put on their rearview mirror. It’s the worst smell on the world.

Dr. Justin Marchegiani:  Oh, absolute toxins.

Evan Brand:  Don’t use those.

Dr. Justin Marchegiani:  Absolute toxins. I remember in high school, I used to love having those in my car like the—the vanilla scent one. I thought it was so cool but then the more I studied it, it was just absolute toxins.

Evan Brand:  So were you the guy who when one of the trees ran out of scent, did you go to the car wash and buy another tree and stack it on or did you remove the first one?

Dr. Justin Marchegiani:  Well, I—I would remove the first one, but I always keep a tree in there to keep it going.

Evan Brand:  Oh, I—I’ve seen people who have 20 trees stacked on one another on their rearview mirror.

Dr. Justin Marchegiani:  I know.

Evan Brand:  They can’t even see out the windshield.

Dr. Justin Marchegiani:  Isn’t that nasty?

Evan Brand:  It’s horrible. Well, actually, Luke who and I were talking about–

Dr. Justin Marchegiani:  Yeah.

Evan Brand:  Before the show–

Dr. Justin Marchegiani:  Luke Storey.

Evan Brand:  Luke—he posted something online about he got in an Uber and he posted a picture of a guy who had like 20 of the black trees.

Dr. Justin Marchegiani:  Oh, God.

Evan Brand:  On his g—on his a—and so he had like a little portable ozone generator that he was breathing in in—in the backseat of the car.

Dr. Justin Marchegiani:  Oh, my God. Unreal.

Evan Brand:  Poor Luke.

Dr. Justin Marchegiani:  I know. What you gonna do?

Evan Brand:  Yeah. Let’s talk about phytoestrogens, too, in the food if—I guess we’ll hit the diet piece again. So these are your sources of soy. So mainly we’re talking about soy bean, your tofu, all of that. Something that’s frustrating for me is when you’re looking for a good protein bar, you may—you might find an organic protein bar at your health food store, but typically one of the first ingredients is gonna be soy protein crisp. It’s like come on, that’s not good.

Dr. Justin Marchegiani:  I know. Whatchamacallit, yeah, Clif Bars has got them. Even I think–

Evan Brand:  Yup.

Dr. Justin Marchegiani:  A lot of the Zone bars, too. There’s only a few bars that actually have decent, clean protein in their bars, but that’s a big one. Soy’s a big phytoestrogen. Outside of miso, natto, or tempeh, soy is—for the most part is not gonna be good. Some menopausal females can get away with a small amount of it, if fermented-wise because it can help modulate their hormones when they’re lower in estrogens, right? Menopausal, but for the most part, people should not be doing soy. It’s not a good thing. It’s—and outside of that, too, we talked about the chemicals. We talked the industrial solvents, the hygiene products. You can always go to the website, or org to look up your products that you use on your face, on your hair, on your skin, your makeup, and see how much chemicals or toxins are in them. Oh, stress! Stress is huge because stress will cause your progesterone which is a major building block of your hormones to go downstream. Meaning it will progesterone and shunt it in the cortisol or stress hormones so you can deal with whatever that stressor is, because your body is hardwired to prioritize stress and inflammation first over recovery and healing and fertility second. And it kinda makes sense because if you’re stressed now, the body wants to deal with that stress, get over it and then because able to repair later, because if it doesn’t deal with the stressor, it may not get to that next point of being–

Evan Brand:  Yeah.

Dr. Justin Marchegiani:  Able to heal and recover. So it’s just allocation.

Evan Brand:  Yeah, maybe you’re—maybe you’re dead and because you got eaten by the bear because your body was trying to repair and run at the same time. It can’t do both, so people who are listening, you know, always have the ancestral lens added as filter on to our conversations because this is very new. All this stuff that we’re dealing with, the environment is so new and we still have this ancient wiring systems that’s thinking–

Dr. Justin Marchegiani:  Yeah.

Evan Brand:  Okay, there’s a bear coming down my driveway right now, I need to be in Fight or Flight, so recovery is—is not prioritized. And people listening, even just you having a notification sound—Justin and I have talked about this before, but even just having notifications on your smartphone or your computer “Ding!” every time you get an email, that’s triggering a biological response in the brain, that’s a hormonal response. Your body’s thinking, “Oh, what the hell is in that email? Is that a bill? Is that letter from somebody I don’t wanna hear from? What’s in that inbox?” That could be a huge source of stress so you really need to—you could either track your heart rate variability or just track how you feel. If you feel your heart racing or gut hurting after you’re expose to social media, something like that, these are the invisible stressors that can really trigger stuff for people and if you put—well, what does that actually do? You’re just saying this. But what does it do? Well, it inhibits the conversion of—of hormone, your T4 to your active T3, and so then you’re gonna have those hypothyroid symptoms and it could all be due to the stress.

Dr. Justin Marchegiani:  Yeah, and just think about it like this, right? If you’re barely getting—barely making enough ends to meet, you know, you’re barely getting enough money to make ends meet, so to speak, right? Do you have enough money to go and start investing in things in the stock market or real estate? Probably not because you’re just so focused on getting the bills paid. That’s all you can focus on. Once the bills are paid, i.e., once you’re able to manage stress and inflammation in your life, then you can think about investments after that, right? Same thing hormonally with how your body is prioritized to allocate bandwidth to essentially.

Evan Brand:  Right, that—yeah, that’s well said.

Dr. Justin Marchegiani:  You can–

Evan Brand:  Do you want talk about–

Dr. Justin Marchegiani:  Yeah.

Evan Brand:  Do you wanna talk about solutions for this? I think avoidance is kind of the—the big one that we could say in one sentence and be done with that, you know? Getting these things out of your life, making sure that you’re eating organic, making sure that you are staying away from the chemicals as much as possible. You’re looking at your skin care products. You’re looking at the makeup, the mascaras, the foundation, all of that crazy stuff that women put on to, you know, they feel like they have to put that on to be beautiful. I promise most women I see, they’re more beautiful without makeup. You look so much better. I tell my wife, “You don’t need it.” Country singers they say—they sing that in their songs like, “Oh, don’t put on makeup.” But it’s a real thing, especially if you have, you know, freckles and—and whatever natural skin pigmentation, that’s pretty. You don’t have to cover that up. So maybe turning off the TV is the first step to get through that process.

Dr. Justin Marchegiani:  Yup.

Evan Brand:  Because women are brainwashed into thinking they have to—to have caked on xenoestrogens to look pretty and they don’t.

Dr. Justin Marchegiani:  Exactly and that’s part of the whole, you know, brainwashing that Hollywood does, is they try to make most people feel incredibly inadequate about themselves so they can go buy some product and you know, frankly, it works. As much as a lot of women don’t like it and they complain about it, but it works and that’s why they do it.

Evan Brand:  Well, because if—yeah, you’re saying because if one lady is gonna wear makeup, then you don’t wanna be the only one without it?

Dr. Justin Marchegiani:  Right. I mean, I—my wife asked me, “Should I wear makeup tonight?” You know, she’s telling—she’s asking me this. I’m like, “No, you shouldn’t.” I like you better without makeup. It’s just—it’s better. It’s healthier.  But–

Evan Brand:  It really is.

Dr. Justin Marchegiani:  But there are some natural things out there. I know there’s a-

Evan Brand:  Yeah.

Dr. Justin Marchegiani:  There’s some—some mineral-based makeups that you can just kinda touch things up and it’s more mineral and more natural-based and it’s easy and you’re not adding a big toxic load. Those will be if you’re gonna use makeup because some people may not be ready to make that switch, but that’s the better next step to look at.

Evan Brand:  I’ve seen a couple organic mascaras. I don’t know how it could be organic. But Hannah’s purchased a few organic mascaras and then also a few foundations. I don’t know if they were considered organic or they were labeled without phthalates. I can’t think of the brand right now. I wanna say it had the name Doctor in it.

Dr. Justin Marchegiani:  Huh.

Evan Brand:  Doctor’s Best or something and it was a brand of makeup. If you look on Amazon, I know there’s a bunch of different companies out there.

Dr. Justin Marchegiani:  Yeah, absolutely. So diving in here, we talked about the stress allocation and how your bodies and your adrenals can be affected by this whole thing, right? Because of the prioritization of progesterone to cortisol. You also touched in on how that cortisol can affect your thyroid because if your hormones start going off, if progesterone starts going off, that can affect thyroid conversion because if cortisol’s out of balance, that can affect T4 to T3 conversion which is your inactive thyroid hormones, so you’re active thyroid hormone. And also progesterone’s a powerful stimulator of TPO, which is the enzyme that helps bind tyrosine and iodine together to make thyroid hormone. So progesterone is really important to building thyroid hormone. So you can see this is why you don’t just get one symptom when hormones go out of balance because it just has this constellation ripple that can happen and many symptoms can occur because of it.

Evan Brand:  Yup, well said. So avoidance. We talked about lifestyle changes, you know, doing what you can whether it’s a floating tank, whether it’s yoga, tai chi, qigong. There’s meditation. There’s gratitude exercises, journaling. You and I have done entire podcasts dedicated to that. I don’t wanna skim over it but I think there’s so much that said about stress that you—you just have to—you have to do it. And if you say that you don’t have 5 minutes to meditate, well, you probably need quadruple that amount of time.

Dr. Justin Marchegiani:  Exactly. Yup, setting a timer like that can be really helpful. Even just sitting and just breathing. Just—just staring literally out—out your window. Just staring and just thinking about the sky or whatever, just clouding your head or just whatever is going on and just think about whatever you’re looking at. That’s why you talk about forest bathing or walking in nature and just being 100% present where you’re at. Oh, look a tree! Oh, look a rock! And all you’re focused on is what your eyes are gazing at.

Evan Brand:  I love it. Yeah, I mean I’m looking outside right now. It’s a beautiful day here. It’s in the mid-60s so it’s getting chilly but the sky is so blue. I mean, I’m so grateful for that.

Dr. Justin Marchegiani:  Love it.

Evan Brand:  To not have a cloudy day.

Dr. Justin Marchegiani:  Love it. That’s awesome.

Evan Brand:  Should we talk about nutrients? You wanna go there in terms of like estrogen metabolism support–

Dr. Justin Marchegiani:  Yeah.

Evan Brand:  Stuff like that?

Dr. Justin Marchegiani:  Yeah, so let’s just kinda dive in the gut because the gut’s really important to the nutrients getting to where they have to go. Would you agree?

Evan Brand:  I, oh—yeah, 100%!

Dr. Justin Marchegiani:  Yeah, so we’ve kinda talked about it when we did our dry run round 1 on this podcast on Friday that got—didn’t quite go through on our side, so we’re even more polished for this podcast round 2. We talked about estrogen hormone conjugation, and conjugation is nothing more than putting a straightjacket on the hormone. Okay, so, you know, because we’re talking about estrogen here, estrogen begins with E so we’ll use Evan as our form of estrogen in this analogy.

Evan Brand:  Here we go.

Dr. Justin Marchegiani:  Alright? So E for Evan, E for estrogen. I’m putting a straightjacket on Evan so I can escort him out of let’s say the—the rowdy club, right? He’s—he’s going crazy. He’s fist-pumping. We’re gonna put a straightjacket on him, escort him out of the club. That’s kinda like what our body does to estrogen. It’s done its thing. It’s going. It’s getting shot back out the gallbladder into the gut to get metabolized. We bind these proteins to it. It’s called conjugation or in this analogy, straightjackets on Evan so we can escort it out. The problem is back gut bacteria imbalances meaning more bad bacteria in relationship to good bacteria in your gut—this is called dysbiosis—this upregulates specific enzymes known as β-glucuronidase. You know it’s an enzyme because it ends on the word –ase. This enzyme basically comes over and takes the straightjacket off. So imagine Evan being escorted out of the bar, right? The club. He’s being rowdy. Someone clips open the straightjacket and now he’s loose and he’s—he’s running away from the bouncer or the police. That’s what happens. Estrogen gets unconjugated or deconjugated. Boom! It can go right back into circulation and cause tissue to grow, whether its endometriosis or cause fibroids to occur, or create hormonal imbalances and symptoms and mood swings, and affects your mood and—and cause you to gain weight. All these different things can happen when we have gut bacteria imbalances. So that’s kind of the—the estrogen-gut detox mechanism. And then we also have the fact that if we have malabsorption because we have too much gut bacteria imbalance, more bad than good. We have low stomach acid and low enzyme levels, well, we’re not gonna be able to break down a lot of the nutrients we need to be able to metabolize hormones, whether it’s B6 or zinc and magnesium or various B vitamins that, you know, help with phase 1 and phase 2 detoxification, sulfur-based amino acids. All these things have to be broken down into their constituents so they can be absorbed and get into circulation and also we need to ionize various minerals, like magnesium and zinc. These are really important minerals. We have ionize them. That basically allows these minerals to get soluble. It’s solubilized into the bloodstream so it can do its thing and be utilized.

Evan Brand:  Yeah, so I mean we could add another layer on top of that. Parasites, yeast, we know–

Dr. Justin Marchegiani:  Yes.

Evan Brand:  With Doctor–

Dr. Justin Marchegiani:  All these things affect that.

Evan Brand:  Dr. Jonathan Wright’s book, Why Stomach Acid is Good For You. We know that any woman listening over age 30, you have lower levels of hydrochloric acid and enzymes than you did when you were 20. So it’s not to—you don’t have to guess and—and check and think, “Oh, do I low enzymes?” I guarantee it. I would suggest and you tell me if—if you suggest different, but I generally suggest anyone over age 30 especially people that busy or eating in a rush or scrolling–

Dr. Justin Marchegiani:  Big time.

Evan Brand:  Scrolling on their phone while they’re eating which is a big no-no, you gotta have enzymes.

Dr. Justin Marchegiani:  100%.

Evan Brand:  Supplemental enzymes that is.

Dr. Justin Marchegiani:  Yeah, I mean enzymes and/or hydrochloric acid because hydrochloric acid actually activates enzymes.

Evan Brand:  Yeah.

Dr. Justin Marchegiani:  Hydrochloric acid activates pepsinogen to pepsin in the stomach and also provides the PA stimulation for the pancreas to produce trypsin, chymotrypsin, lipase, a whole bunch of other proteolytic enzymes that are really important. So without HCl and/or enzymes, you’re gonna be in a world of hurt when it comes to digestion. And most women don’t get this, men as well, but they don’t understand the fact that you can have digestive problems and may not actually have digestive symptoms. People think, “Well, hey I don’t have diarrhea or constipation or bloating, I’m not too gassy, I don’t burp too much, I don’t have any acid reflux, and I got to the bathroom every day. Hey, I don’t have a problem.” Right? But a lot of times, their moodiness, their PMS, they migraines, their other issues in their body–

Evan Brand:  Yup.

Dr. Justin Marchegiani:  Can be driven by the inflammation going in their gut because they’re not—they don’t or they’re not expressing with atypical—I’m sorry, they’re not expressing with typical gas symptoms, bloating, gas, constipation, diarrhea. They’re expressing with atypical, outside of the norm symptoms that just are really hard to be connected and their medical doctor they go to won’t ever recognize it because they are great, they’re depressed—could be a hormonal issue, could be a gut issue, but guess what? They’re gonna be put on Wellbutrin–

Evan Brand:  Lexapro.

Dr. Justin Marchegiani:  Lexapro, Paxil. Hey, you know they’re feeling, you know, a little bit anxious. Great, they’re gonna get thrown on Xanax.

Evan Brand:  Ugh.

Dr. Justin Marchegiani:  Hey, you know, they’re feeling like their cycle’s a little unstable, they’re getting thrown on a birth control pill. It could totally be from–

Evan Brand:  That’s horrible.

Dr. Justin Marchegiani:  All the other dysbiosis and the poor detox happening in their gut.

Evan Brand:  It’s horrible, man. It’s horrible. I had a female last week, she asked me—we found Giardia and Blasto—the double, double trouble there.

Dr. Justin Marchegiani:  Double trouble.

Evan Brand:  And she said, “Well, I don’t have any gut symptoms. Do we still have to treat it?” I said, “100%, you can—just because you’re, you know, not running to the bathroom with diarrhea, the typical manifestation of Giardia, it doesn’t mean we can just let it stay there.” Could you—maybe you would have a—a more, a better answer than me. I just said, “Absolutely.” But I know there could be more to that. You can be as long-winded as possible with this.

Dr. Justin Marchegiani:  Well, I tell people that everyone has the right to be infection-free, right? That’s my goal. To make sure everyone’s infection-free. Now the problem is everyone also has the right to have more than one issue going on at once. So a lot of patients, they have hormonal imbalances, but they also have other issues that are driving the hormonal imbalances that don’t necessarily from bird’s eye view connect, i.e., the Blasto and Giardia and this girl’s female hormone or mood symptoms. So–

Evan Brand:  Yup.

Dr. Justin Marchegiani:  Yeah, so anytime there’s a stressor, that’s an issue. It’s like you walk into your house. Okay, let’s say you have a couple of guest bedrooms. Let’s say you don’t go in those guest bedrooms for a while. The guest that was in there last left the water running just a bit. You don’t know it. You don’t hear it. But you get this water bill every month and it’s just a little bit higher than you’re used to and you’re like, “Why the heck is my water bill 30% higher? I’m barely even using it. I’m gone half the month. What’s going on?” And then you look over and you’re like, “Oh, the water in my guest bedroom’s on. That’s what it is. I’m gonna turn it off.” Now what’s this equal? Having water in your guest bedroom on is like having a parasite or a bug stealing your nutrition, pooping inside of you, i.e., creating biotoxins, creating inflammation and maybe even creating leaky gut which is stressing your immune system which takes up energy. All of those stressors like that parasite or infections involved in, toxins, malabsorption, leaky gut, immune activation, that’s nothing more than draining your energy. So instead of your energy being allocated to performance and recovery and healing, right? It’s going towards something else. Just like your water bill’s being sucked towards these guest bedrooms that you don’t even—you’re not even aware of them because you’re not there on a day-to-day basis.

Evan Brand:  Now so from the nervous system perspective, couldn’t we say that you’re gonna be sympathetic dominant, more fight or flight?

Dr. Justin Marchegiani:  More, 100%. Yeah.

Evan Brand:  Because you’re fighting an internal battle.

Dr. Justin Marchegiani:  Bingo! And the problem, the sympathetic nervous system, the allocation because we’re hardwired this way and it totally makes sense is when the fight or flight, the sympathetic, that’s like the gas, go, go, go, go, go. That’s the gas, the sympathetic fight or flight nervous system shuns blood flow towards the muscles, towards the outer extremities because we have to fight and flee and we need oxygen and nutrition and glucose to get to those outer extremities so we can perform. If the blood glucose is inside the intestines and inside all the organs where they should be and they’re digesting, you will not be able to run as fast. That’s the main reason why activity after your meal is destructive for your digestion, you get an upset stomach. Remember the old analogy of like, “Hey, you shouldn’t go swim. You should wait, what, 2 hours or an hour after you eat to go swimming.” Why is that? It’s because at some point, someone did that and they got a cramp because there wasn’t enough blood flow or they got an upset stomach and got sick.

Evan Brand:  Yeah.

Dr. Justin Marchegiani:  So–

Evan Brand:  Because you’re trying to rest and digest and be active at the same time. You can’t do it.

Dr. Justin Marchegiani:  Yeah, and the analogy is this, right? If the sympathetic fight or flight nervous system is your foot in the gas, and if the digestive system and relaxation and repair is the brake pedal, what happens when you hit the gas pedal and brake pedal at the same time?

Evan Brand:  Yeah, it’s not a good—not a good—not a good picture.

Dr. Justin Marchegiani:  No, no, exactly.

Evan Brand:  Yup.

Dr. Justin Marchegiani:  You’re—you’re spending a lot of time going nowhere fast.

Evan Brand:  Yup, so to wrap this whole segment up of—of this part of the—the conversation. If you’re someone listening, especially female, or you and I are working together, you’re working with Justin already, and you tell us, “Yeah, but my life’s not that stressful. I’m not that stressed.” It doesn’t matter because all of this hormonal imbalance and these symptoms that you have could all be going on due to something in your gut. And Justin, you and I both are—we’ve seen false negatives on stool test results. So sometimes it may take one or two or three times to really find what’s going on. So if you’ve gone to your conventional doctor or even the gastroenterologist, the specialist you’re gonna get referred to that’s gonna throw you on prescription acid blockers, if they run tests on you and how up negative, don’t necessarily take their word for it. I hate to say this that these prestigious hospitals and et cetera are missing infections but you and I see it every single day in the clinic and we’re finding these infections. So if you actually get something on a piece of paper, you’re gonna have a lot more room to work with. So don’t just go buy hormone balancing or hormone this or hormone that supplement. You really need to get to the root of the root which in some cases could be the infection route.

Dr. Justin Marchegiani:  Oh, 100%. And again, really looking at everything holistically is really exactly how you have to do it because of the interplay with body systems that may not typically connect to the average person because you know, they’re not a trained functional medicine clinician and definitely will not connect with the average conventional medical doctor because they’re training is drug symptom, drug symptom, drug symptom, and they don’t look at upstream stressors and body systems that may be out of balance.

Evan Brand:  Sure, so I’ll put it even more—even more direct. If you’re going to your OB-GYN or your endocrinologist, they’re not gonna have a clue about you having a cryptosporidium infection in your gut and giving you an herbal protocol to remove that infection so that your hormones come back into balance.

Dr. Justin Marchegiani:  100%.

Evan Brand:  It’s never gonna happen. I mean, I will—I will bet you know every silver bar that exists on the planet that—that you’re not gonna get it. If you do, then that doctor, they—they’ve stepped up their game and they’ve done some functional, you know, they’ve taken some functional courses.

Dr. Justin Marchegiani:  And sometimes it’s good like get that workup done. You know, just you know, go with the low-hanging fruit. I find most of the time patients come to see me and that’s already been done–

Evan Brand:  Yeah.

Dr. Justin Marchegiani:  And it’s already been missed but hey, always start with what’s the easiest and you know, what I consider to be the low-hanging fruits, that way you know you’ve crossed your T’s and dotted your I’s so to speak and then you can go up the chain regarding the—the functional medicine, you know, ladder so to speak.

Evan Brand:  Sure, and I guess we could briefly talk about, you know, the financial aspect of it, too. If someone does have health insurance or they’re able to go see a doctor through their work and it’s at no charge to them, then you might as well try to milk that for as much as you possibly can, but unfortunately in most cases the lab results that get sent over to you and I that we review, there’s not much evidence there. We can’t really work with that. We really have to do the more functional tests which are an investment but sometimes that’s what it takes.

Dr. Justin Marchegiani:  100%. So looking at this point here. If everyone listening or anyone listening is dealing with a—a hormonal imbalance, whether it’s men and just having low libido and—and poor muscle tone or women having PMS or menopausal symptoms or everything in between that we already mentioned, the whole litany of—of different items there, the next step is gonna be one, digging into the female hormones, right? Testing hormones at the right time of your cycle. We test female hormones typically around Day 20 or so if we’re looking at progesterone to estrogen. Some we even run a month-long cycle to see how the hormones fluctuate every other day. And some will even dig deeper into looking at thyroid as well as a full gut panel. So depending on where you’re at, if you’re having issues and you’ve already kind of ruled out the things we’ve already talked about on the diet and lifestyle, the next step would be to step it up regarding the functional medicine’s options that are available and kind of our—our palette if you will.

Evan Brand:  Yup.

Dr. Justin Marchegiani:  So the next step would be to reach out to either myself, to Evan, notjustpaleo, Dr. J myself, or some other competent trained functional medicine doctor or practitioner to get everything kinda lined up in order based on what we talked about in the podcast today.

Evan Brand:  You hit on the—the last word that I wanted to say is the order.

Dr. Justin Marchegiani:  Yes.

Evan Brand:  You know, something that is very important for anything, you know. If this is just adrenal problems or just hormone problems or just gut problems, whatever it is, it has to be done in the right order. Please, please, please don’t add to your supplement graveyard because you read about some product on Amazon or you saw it at the health food store and it was in the hormone section. Save your money because if you’re doing things in the wrong order, you’re really just wasting your money. Now I’m not gonna say that taking a zinc supplement is necessarily gonna make you worse because we know that–

Dr. Justin Marchegiani:  No.

Evan Brand:  70% of women or more are not getting enough zinc, so yeah it’s not going to hurt you. It might help you but why go and spend all this money if it’s not done in the right order because you’re gonna save so much more money in the long run if you do things in the right order by working with a practitioner.

Dr. Justin Marchegiani:  Well, it’s like baking a cake, right? Let’s just pretend it’s a gluten-free flourless cake for our—for our healthy analogy, right? You have the eggs. You have the—the coconut flour or you have maybe some Stevia in there, whatever else, maybe some grass-fed butter or coconut oil. Well, how we mix things in baking a cake is really important to the outcome of the product, of the outcome of the cake.

Evan Brand:  Yeah.

Dr. Justin Marchegiani:  So let’s say you—you do start doing a heavy metal cleanse first, gut-killing second. You work on the diet 3 months into it and then you don’t touch the hormones and the thyroid til month 4. Well, you did a lot of things that were supposed to be done but they were just all done in the wrong order. Just like making a cake, you cook it before you mix the eggs and then you add the—the Stevia at the end or whatever. It doesn’t come out to be a nice-looking cake.

Evan Brand:  Yup, yup, Well-said.

Dr. Justin Marchegiani:  Anything else you wanna add, Evan?

Evan Brand:  I don’t think so. I think this is—this has been good coverage. Share this, if you have somebody who’s going through all this stuff. I mean, I could think of 20 people right off the top of my head who I know have problems with estrogen metabolism or estrogen dominance. So sharing is caring. This is the information that has to get out there. We’re gonna continue doing our work, we’ve got, you know, between Justin and I both, we’re over—likely over 6 million. I haven’t counted. I know for sure, 100% guaranteed over 5 million downloads of conversations that we’re having, probably up to 6 million by the 4-year anniversary of my show which is coming up really darn quick. I think it’s November 11th of 2012–

Dr. Justin Marchegiani:  Wow.

Evan Brand:  Would be the 4-year anniversary. So that’s—that’s a lot of people but that’s still not enough. That—I mean look at the suffering out there. Look at the people that are going and they’re spinning their wheels and they’re buying these diet programs and they’re buying these fitness books and they’re not getting the answers and they’re beating their heads against the walls, and they’re buying you know, diet root beers and look at Pepsi. I mean they had to bring back their aspartame version of their Diet Pepsi because so many people complained about the taste, you know? So don’t prioritize the taste. You know, prioritize the—the quality of your—of your liquids, the quality of your nutrition. Prioritize that better over taste and if you ask me, I think aspartame tastes horrible and it’s a neurotoxin, not to mention. So always look at something through the lens of the quality, not necessarily the taste or the cost or—or all of that, because you’re really gonna save yourself a lot of trouble if you start turning around the boat now as opposed to waiting til when you hit rock bottom and then you’re coming to Justin or myself and then you’re saying, “Look, I’ve had this stuff going on for 20 years.” Well, how long have you known something was wrong? “Well, I knew I should have gotten help you know, back in 2003, but I didn’t.”

Dr. Justin Marchegiani:  Right.

Evan Brand:  You know, don’t be—don’t be one of those people. Thousands of people have come to our clinics. It’s your turn. If you’re suffering, stop suffering. You don’t need to.

Dr. Justin Marchegiani:  Bingo. Love it, Evan. Well, feel free and reach out to Evan at, Dr. J myself, or Subscribe to the podcast and the YouTube channel and we look forward to providing more information very soon.

Evan Brand:  Check out Justin’s videos. He’s over 20,000 subscribers on YouTube. He’s gonna be—I’m telling him, he’s gonna be the King of Functional Medicine on YouTube.

Dr. Justin Marchegiani:  Just able to help more people. I love it.

Evan Brand:  Yes, sir. Take care!

Dr. Justin Marchegiani:  Have a good day, Evan.

Evan Brand:  Bye!

Dr. Justin Marchegiani:  Bye!


Estrogen dominance, female hormones and your health.

By Dr. Justin Marchegiani

Estrogen, one of the two main sex hormones that women have, is responsible for female physical features and reproduction. Today’s talk is going to be on estrogen dominance.  Again, anyone that has female hormone symptoms for the most part, it is going to be a contributing factor to why you’re having those symptoms.

So I’m fresh off an interview I did today where we talked about estrogen dominance in one of the local summits that went here and I want to dig in a little bit deeper and give you some of the tidbits and the factoids of what causes estrogen dominance. Also, how it actually looks on the lab work, and what are some simple things that you can do to help to start improving it in the right direction.

What is Estrogen Dominance?

We have this ratio of estrogen that’s a little bit higher in relation to what the normal ratio of progesterone should be.  So let’s establish what those norms are.  So Dr. John Lee talks about the fact that progesterone to estrogen, that amount of progesterone to estrogen can be anywhere between 200 to 300 times.  So progesterone can be 200 to 300 times more than 1 molecule of estrogen.

Now typically, we see this 200 to 300 per ratio right around day 20 of our female cycle.  Day 20, so right here is where we typically see this ratio intact.  Now right around day 20, we could be making about 200 micrograms of estrogen. While we’re making 20 to 25 milligrams of estrogen, that 200 or 300 time ratio can be seen.

Now if you add all the plots of progesterone up in blue and all the plots of estrogen in red typically on average, this will be day 18 to 22 roughly.  But if we’re looking at an average, typically you’re looking at about the 23 to 25 times ratio for progesterone in relationship to 1 estrogen.

To delineate, typically around Day 20, we’re looking at a 200-300 progesterone:1 estrogen. While over here, a 23-25x progesterone:1 estrogen, in general.

So, this is from a research of what Dr. John Lee.  He’s written a couple of books on this topic.  So when we do a month-long cycle, we can really delve in and see some of these imbalances.

Got female cycle problems? Click here to get more in-depth information on how female hormones work in your body.


Female Hormone Cycle Overview

Let’s walk through normal female hormone physiology briefly.

  1. Drop in hormones: This triggers menstruation or bleeding. That’s important because it’s causing the endometrial lining to slough off.
  2. Menstruation / Bleeding / Period
  3. Increase in FSH. This increase in FSH grows that follicle into an egg. That follicle then starts to produce an increase in estrogen.
  4. Increase in estrogen: Increase in this hormone causes LH or luteneizing hormone to trigger increase in progesterone. It peaks typically around day 12 or 13.
  5. Increase in Progesterone: It spikes typically around day 18 to 22. That’s where the ratio 200-300 progesterone:one molecule of estrogen can be seen.
  6. Drop in Progesterone

That’s our normal female hormone cycle and typically we start to see the ratios skewed. Our average Progesterone:Estrogen (P:E) is 23-25x. And at day 18-22, it is about 200-300x.

That is estrogen dominance affecting the female cycle. We start to see these ratios skewed.  So estrogen dominance would be occurring when we start dropping below 20. Most women I see are in that 20- 50 to 20-80 around their peak, where they have significant less progesterone, but they also have a lot less estrogen, too.

Female Hormone Level Imbalance

I see a lot of women whose hormones are very depleted where the ratio may not be great, but it’s the hormone level by itself that is may be even worse.  So estrogen dominance is really just looking at a ratio.  You can still have low estrogen and low depleted hormone levels and still be estrogen-dominant.  That’s kind of a big myth and depleted hormones make it really hard for you to heal and regenerate.

So looking at estrogen dominance symptoms, we have bloating, cramping, fibroids, tissue growth, moodiness, and endometriosis. It is a hormone signal that causes cells to grow.

Progesterone is a hormone signal that causes cells to grow up, ideally mature. So growing is like me lifting weights and just getting big. So that’s the estrogen analogy. The progesterone analogy is like a child growing into an adult. One is maturation.  One is just bulk.

Now estrogen is important because we need that when it comes to certain tissue like in the endometrial lining, but progesterone is important to help that egg bond to the endometrial lining and then essentially maturize into a grown baby.  That’s the goal and that’s why these hormones, they’re on a teeter totter and they’re incredibly important.  But if we have this imbalance in progesterone and estrogen, all of those estrogen dominance symptoms can happen.

Kinds of Estrogen

So we have a couple of different kinds of estrogen.  We have DHEA which is a part of the adrenal hormones, but it’s also part of the ovaries, too.  That converts to our main estrogen, estradiol.  Estradiol, otherwise known as E2–look at that prefix here with the di, E2 can get converted into E1.  You can see the estrone–look at the O-N-E.  And this can go either one of two ways.  It can go to our 2, which is our more healthy estrogen or it can go to our 16, which is our more anti-healthy, unhealthy, disease-promoting estrogen.

And again, our ratio is we like to have greater than 2 over here to 1.  So we like a 2:1 ratio or greater for healthy estrogen balance.  Estrogen dominance is kind of the macro view, the telescope view.  Now we’re looking at estrogen metabolism.  That’s more of the microscope and the microcosm view.  These are just how estrogen is being metabolized.  But this is important, too, because you can have more bad estrogens on this side of the fence, and then you may experience more estrogen dominance symptoms because of the fact you have this imbalance ratio.


The Metabolic Process in relation to Estrogen

Estrogen dominance is estrogen in relationship to progesterone. But we also know that how estrogen is metabolized can also create estrogen dominance symptoms.  So a lot of people that we see–we’ll run organic acid testing and we’ll look at these various organic acids like sulfate or pyroglutamate, hippurate, glucarate,. Also, we’ll see backed up metabolic processes or pathways to metabolize these hormones.  Another is we see something known as beta-glucuronidase, where we have an inability to metabolize some of these estrogen hormones.

So think of beta-glucuronidase as an enzyme and it’s there to take the straitjacket off of our metabolized estrogen.  So when our body goes and metabolizes hormones, it conjugates it.  It binds a protein to it. In other words, puts a straitjacket around it so it can escort it out to the kidneys and the liver and the stool.

Now beta-glucuronidase, this enzyme occurs when we have dysbiosis, a high amount of bad bacteria in the gut, in relationship to good bacteria. That beta-glucuronidase comes in, it unhooks the straitjacket and now the estrogen can go back and become reabsorbed and create lots of hormonal issues.

Again, estrogen also makes bile sludgy and this is why people that have estrogen dominance can also have digestive issues because bile is so important for fat breakdown. And you actually need good fats to make your hormones. So you can see how estrogen and digestion actually compound each other and make your hormone issues worse in the future. If you can’t make bile, you can’t break down fat. And if you can’t break down fat because bile is needed to break down fat, then you can’t make the fat into your hormones.  So you can see how one problem actually makes the other problem worse and worse as you go on.

Estrogen in the Body and in the Environment

Bad amount of beta-glucuronidase from this imbalance in bad bacteria and infections then takes the straitjacket off all these metabolized estrogens.  They get reabsorbed into the system and that can create more hormonal havoc.  So you can see, estrogen dominance in our cycle.  We can see it through our metabolites and then now we can break it down via the environmental causes.


The gut, through the beta-glucuronidase, through the dysbiosis, through the SIBO, through parasitic and fungal and bacterial issues.  All of these things cause low stomach acid and low enzymes, inability to break down food.  We can’t break down our food.  Our food sits in our tummy.  It rancidifies.  It putrefies and it makes the problem worse.  So one problem kind of begots the next.


So the pesticides, the chemicals, the GMOs.  Again, these pesticides are estrogenic-based.  So they go into our body and they have an estrogenic load to our body.  So pesticides add more estrogens.  The plastics contain estrogens as well.  And again, estrogen cause cells to grow.  The scientists back in the late 1990s, Dr. Sotomayor, over at Tufts found that when she put her cells into the plastic test tubes, that the cells would grow more vigorously in these test tubes, kind of like cancer does. She found that it was the plastic test tubes especially the BPA was causing those cells to grow.


So now flash forward, people are putting their food and their water in plastics all over the place and we’re reabsorbing those chemicals which cause our cells to grow. This is because they have an estrogenic like effect.  So environmental estrogens from food and from plastics and then also from phytoestrogens contribute to estrogen dominance.


Soy can be devastating because there’s a lot of gut and enzyme inhibitors in it such phytic acid and oxalic acid and chymotrypsin in various trypsin inhibitors, which affect protein breakdown but they’re also estrogenic.  They can add to your hormone levels of estrogen and for many, can be incredibly devastating because estrogen is the opposite of testosterone.  And men need testosterone to be healthy and virile.


So again, we have the gut and we have food.  We have phytoestrogens and we have plastics, and again all of these are so important. Also, if we don’t have the gut working, we don’t have the building blocks to make the hormones, which then makes the problem even worse.  For so many people, it’s hard for them to wrap their head around the fact that their gut could be a potential hormonal causing factor that could be driving a lot of their hormone issues.  People think the gut and the hormones are like two separate things.  “Hey, if I don’t have digestive issues, well, there’s no way that’s part of my hormonal issues,” but it can be.


If you have a hormonal issue or long-term issue, we may want to run a month-long test, if not, a test that looks at hormones especially in the sensitive time of your cycle around day 18 to 22.  We may also want to do an adrenal test to get a window into how your adrenals are functioning because your adrenals produces a significant amount of DHEA, which is depleted in people that are chronically ill.

We also want to dig into the environmental and lifestyle causes over here that could be driving the issue.  And there’s a lot of natural cyclical augmentation programs and adrenal programs and gut-healing programs that we do on the functional medicine side to address the underlying cause of what’s driving these issues.

So click on screen, subscribe to my female hormone balancing video series. And if you’re struggling with this issue, and you want to take it to the next level and get to the root cause, reach out on screen or below and I’m always here to help.

Discover the root causes of your female cycle issues by contacting a functional medicine doctor.

The entire contents of this website are based upon the opinions of Dr. Justin Marchegiani unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Justin and his community. Dr. Justin encourages you to make your own health care decisions based upon your research and in partnership with a qualified healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Dr. Marchegiani’s products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products.