The Allergy and Hormone Connection – Natural Allergy Solutions – Part 2 | Podcast #314

Hormones have profound and significant effects on your physical, mental, and emotional health. In this video, Dr. J and Evan continue their discussion on how these chemical messengers have a significant role in regulating your mood, appetite, and weight, among other things. 

Typically, your endocrine glands produce the precise amount of each hormone needed for various processes in your body. However,  hormonal imbalances have become increasingly familiar with today’s fast-paced modern lifestyle. Besides, hormones decline with age, and some people feel a sharper or dramatic decline than others. 

The bottom line is, your hormones are involved in every aspect of your health. You need them in precise amounts for your body to function fully. Hormonal imbalances may increase the risk of obesity, heart disease, diabetes, and other health problems. Although aging and other factors are afar your control, there are many ways you can take to assist your hormones function well. Consuming healthy foods, meditating, exercising regularly, and engaging in other healthy behaviors can go a long way toward improving your hormonal health.

Dr. Justin Marchegiani

Dr. Justin Marchegiani

In this episode, we cover:

1:21     Hormone Connections, Menopausal

8:24    Nutritional Deficiencies, Food Diets

15:58   Proper Lab Testings, Reading Hormone Profiles

22:07   Men and Female Hormones in Allergic Disease

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Dr. Justin Marchegiani: And we are live. It’s Dr. J in the house with Evan Brand really excited today we’re going to be talking about the allergy hormone connection. We did. We had a nice chat last week on natural solutions, functional medicine solutions for allergies. So I’m actually very excited to go over the hormone connections, we won’t be going into as much on the supplements or, or things that we do on that side of the fence. We’ll put a link down below so you can see that first podcast. This is going to be building off of that podcast. So if you’re coming in late to the game, you want to take a look at that first podcast, we’re going to be really dive diving in and connecting the hormone piece to it. Because there’s a lot of people that have estrogen dominance, menopause, hormonal issues, imbalances in their adrenal function, and part of that could be driving their allergy issue and you really got to look at everything holistically. And we’re going to be connecting the dots for you guys today. It’s always context, context, context. Evan, how are we doing today, man? 

Evan Brand: Doing good, always good to see on a Monday, it’s like the best part of my week is to start off with a bang. So I actually got a lot of good feedback last week on that podcast, too, you know, you and I kind of joke about how it’s a thankless job because we’ll put out an episode get 1000s and 1000s of downloads and not hear much but actually had a lot of people messaged me and said that that allergy when we did was one of the best of the year. So appreciate your feedback. And we’re excited to take it a step further.

Dr. Justin Marchegiani: Love it, absolutely love it. So out of the gates here, I mean, there’s kind of maybe three categories of patients that I see really benefit from a lot of this out of the gates. So first are going to be our menopausal females,  and menopausal is the one study that we’ll talk about here today that showed menopausal and perimenopausal women having two times the likelihood of having allergy issues. Part of that has to do with the drop in progesterone and the imbalance and progesterone estrogen that can skew the immune system. The other one would be a cycling female who has significant estrogen dominance, massive imbalances in progesterone and estrogen, that’s another kind of category. And then the last would be someone it could be male or female that has significant imbalances and cortisol, right? We know, when you’re having allergic reactions, you’re developing and producing all these inflammatory cytokines, right, interleukin cytokines, and these are pro inflammatory. And our adrenal glands make a natural anti inflammatory hormone called cortisol. And cortisol naturally will have combat and balance out some of the pro inflammatory cytokines. So if we have significant imbalances, and cortisol, cortisol is too high, and and we’re too catabolic, or it’s too low, and we’re not able to combat the inflammation that can really be I think, the starting mechanism of this whole allergy cascade.

Evan Brand: Yeah. And you and I were talking before we hit record about, well, why is it such a problem now, because you look at like tribal societies and such, and you don’t really see any discussion or any big issue with menopause. And we were talking about the difference in the lifestyle, of course, you don’t have the stress as much as we do in the, in the tribal societies, as you do in modern society. You’ve got more family support group, you’ve got parents and grandparents and the whole tribe helping to pinch hit in some of the family roles. And so really, the the, we’ve lost our tribe, and that baseline stress is really just so strong on people that when there’s the transition to menopause, the adrenals have already been weak for 40 years of parenting with just you and your spouse, that, you know, it’s the straw that breaks the camel’s back.

Dr. Justin Marchegiani: Oh, I agree. I think you also have a lot more environmental toxins, you have increased nutritional deficiencies, you have a lot more pesticides in the environment, all those different things. Now imagine if you’re like, you know, living out in the forest or something in some kind of a hotter teepee, or some kind of a structure, there’s quite a lot of environmental molds, just things decaying around you. So there’s probably a lot of that by a lot of rain getting in there. So it’s amazing, probably a lot more natural mold exposure, maybe being out there but you know, a lot less stress on the other side of the fence as well. So I think we know stress plays a major role on your adrenals because cortisol is a natural stress hormone. It’s anti inflammatory. It’s a gluco corticosteroid, which means it pertains to stress and inflammation. It’s also a very powerful Energizer hormone. And cortisol can pull from progesterone. So we know progesterone does have anti inflammatory effects. So for chronically producing cortisol, that can really start to skew this estrogen progesterone balance. Because as cortisol is being stimulated due to chronic stress and inflammation, progesterone can be pulled downstream to make it because progesterone is a building block of cortisol. And if progesterone is being pulled downstream, what can happen to that natural ratio of estrogen progesterone, it can skew now. Typically speaking, progesterone is always going to be higher than estrogen in general, usually it’s about a 23 to 25 times ratio of progesterone, estrogen, but at that ratio starts to drop. So we start talking about estrogen going up, and progesterone dropping. We’re talking about that more in relative terms. not absolute, we’re talking about the ratio dropping, not the absolute numbers going in opposite directions just to make sure that’s clear for everyone.

Evan Brand: Yeah, let’s also tie in the gut piece. I mean, a lot of people responded to me and said, Wow, I didn’t have a clue that bacterial overgrowth in my gut could create the allergies. But in the same vein, the gut issues could actually create the hormone issues. So let’s talk about that for a minute. When you are looking at stool test, and we’re going to look at beta glucuronidation, being high due to a bacterial overgrowth. Now we have the recirculation of hormones happening as well. So there may be this point where we come in with some of the herbal anti histamines that we talked about. But now we also may need to come in with some of the glucuronidation pathway support like your calcium D glue, great, maybe the sulfur based amino acids glutathionre broccoli seed extract, like broccoli sprouts, we like to use those. So that’s another mechanism. I think that once again, the allergist, they’re going to miss they’re not going to give you a calcium D glucrate, but they might need 200%.

Dr. Justin Marchegiani: Yep. 100%. I’m going to read a study here. I’ll get the exact article here for you down the road. But here is the quote, study in Northern Europe included over 2300 women and track their respiratory health from 2000 to 2012. They found the odds of getting asthma quote, we’re more than twice as high for women going through menopause or transition, or after menopause compared to non menopausal women. So there’s something that’s happening at around Peri and or menopausal timeframe. So let’s say early to mid 40s, to early to mid 50s. Right. There’s that timeframe that’s happening, I think the big thing that’s probably happening is you’re having a drop in progesterone. And then we’re starting to happen as you’re having FSH and LH starting to increase. And I think you’re also starting to rely more on the adrenal glands to fill in the gap. And if cortisol is out of balance or imbalance, there is not enough DAGA you’re gonna find a real deficit and some of these hormones and you’re not going to have the same inflammatory backup generator support, if you will, from the adrenal gland. And that’s a big mechanism that’s active here. And that’s why you’re going to see more Peri and menopausal women affected and again, a lot of women are chronically stressed and they kind of fall into that perimenopausal category younger and younger. I’m seeing a lot more perimenopausal symptoms and women in their 30s and early 40s. Now, which is really interesting. I mean, perimenopause is that timeframe before menopause. Usually menopause is when you have one year 12 months without a period. But you can start to see perimenopausal symptoms start to happen younger and younger and younger, I think because of chronic stress. And that could be hot flash issues. Of course, that could be just a lot of the PMS issues. Usually you start to see cycle, missing cycles, hot flash issues, you can also see a lot of mood changes, vaginal changes, sleep issues, weight issues, you can see mood, irregularity, loss of libido. And now again, a lot of those also connect with PMS too. So it’s kind of hard to connect the two but usually you start to see missing cycles and starting to see some of those hot temperature issues starting to occur. And then of course, a lot of vaginal dryness or a lot of mucous membrane dryness issues as well.

Evan Brand: Yeah, that was my next question for you is why are you seeing this in younger women? I mean, because this is kind of a new phenomenon, right? I mean, in the last 10 years, you’re seeing this thing is ramping up significantly. So you think it’s just the stress in the 30s to early 40. Women that maybe previously wasn’t as intense. 

Dr. Justin Marchegiani: Yeah, chronic stress, chronic inflammation. I think a lot of women I mean, this is this is in general, this is people in general, just a lot of nutritional deficiencies due to chronic poor diets. A lot of women if they, you know, 20 plus years ago, they were in that low fat era, and they weren’t getting good healthy fat and good healthy cholesterol, I mean, that’s going to put a lot of stress on your hormones, because you need these building blocks. To make these hormones right hormones made from cholesterol, your body makes a lot of cholesterol, but could never make enough. And you need a lot of important fat soluble vitamins in cholesterol from good healthy animal products that to ideally make it optimally right. It’s hard to do that on a vegan vegetarian diet, because you’re just missing a lot of those fat soluble vitamins, and long chain omega three fatty acids that you get from high quality fish and such. So that’s I think a big thing as well. And also fats play a really important anti inflammatory role, right? We know good healthy fats, like fish and coconut, or have good anti inflammatory benefits. And we know a lot of the Omega six in plant based diets can be more inflammatory. And a lot of the good healthy omega threes on the plant based side that come from flax or chia, right, these are going to be like alpha linoleic acid, these are going to be omega threes, they have to get converted downstream and they go through different enzymes like Delta five desaturase, that makes that conversion. And if you have insulin resistance, or inflamed, it’s going to be harder to maximally convert that some people say maybe only 20% converted. So there’s a lot of conversion issues downstream. We see the same problem with vitamin A. So if you’re a plant based and you’re relying on a lot of beta carotene, for instance, and carrots plant based products, you may not get a good conversion cuz that’s the UK converted. So if you’re getting vitamin A from grass fed liver or beef, or let’s say called liver oil, right or egg yolks as a maximum conversion there because you’re getting active vitamin A in there versus having to rely on a conversion, and the more inflamed you are and the more stressed you are, it’s hard to convert an activate a lot of these nutrients.

Evan Brand: Yeah, well, you know, you gotta you made a good point, too, you got a lot more women doing things they shouldn’t be doing like going on strict vegan diets, doing plant based burgers, getting off of real Whole Foods. So I think I’m trying to just answer my own question in my head here. Like, why is this being ramped up in younger women. And I think there’s a combination of factors like always, but man, it, you got Bill Gates and other people pushing so hard, just get off meat, meats, bad meats, bad, there’s still so much on brainwashing that we have to do in the population. So I really hope folks listening into the podcast, we really hope that you all are eating good quality fats, especially women, we really don’t want you to be afraid of those.

Dr. Justin Marchegiani: Yeah, and kind of my pitch on meat versus plant based products. It’s pretty simple. So number one, plants bio accumulate nutrition. So the benefit that you get from animals is they buy or accumulate plants. So for instance, about one meats, one pound of grass fed meat, it takes about eight pounds of plant matter to make that grass fed meat. And so animals face make sure I say correctly, animals bio accumulate plant based matters. So you get a lot more bio accumulated nutrition. So for instance, 16 cups of kale gets you the amount of protein that’s in six ounces of grass fed beef, right, there’s a bio accumulation of amino acids and fat soluble vitamins, and even things like zinc. And then when you go and look at the bioavailability, of course, plants have a lot more anti nutrients than animal products do. So you have a lot more anti nutrients binding up oxalates phytates mineral blockers, protein blockers that make it harder to break down a lot of the nutrients in plants. And then the my sentience kind of emotional argument is, it’s all about taking, it’s all about having the most the largest amount of nutrition per death, okay, it’s really important, you have nutrients per death, if I have one cow kill for my family, that’s gonna feed my family the whole year, right? If you look at a lot of the factory farming involved in, like, let’s say raising high quality plants, and again, this may not be the broccoli or kale in your backyard, right? But if you look at on a wide scale kind of monoculture kind of scale, there’s all kinds of rabbits and snakes, and badgers and all kinds of things that get caught up in the combines when they harvest a lot of these plants. Okay, so there’s a lot of deaths happening. And so then you got to say, well, is that badgers death equal to this cow’s death, right, then you got to look at and kind of weigh well, whose life’s worth more. And then the third argument a little bit deeper is, well, are you taking the life when you’re killing a plant, and I think my personal belief is, it takes life to sustain life. So everything that you kill, whether it’s plant or animal has to have some level of life force to it. And then you’re just playing this game of well, whose life matters more obviously, I can emotionally connect with the cow because it’s got a mommy and a daddy. And it’s cute and cuddly. Maybe not with the kale, right? But all life, it takes life just to stay in life. So there has to be some level of life in that plant, for it to sustain you. Same thing with the animals. And so keep that there. And of course, when we talk about animals, we’re talking about non factory farming, we’re talking about organic, we’re talking about super high quality raising no hormones, no antibiotics, you know, one bad day for that animal. And that’s it. Right. So I just wanted to differentiate that for people that are kind of listening in on the fence with that.

Evan Brand: Yeah, well said, well said I liked the way you you put it. Alright, so this study and paper that you had, it also mentioned vitamin D. Now, just in case, we didn’t mention it last time, I just want to make sure we mentioned it now that there is definitely a link between more severe asthma symptoms and low vitamin D. So that’s a very, very easy low hanging fruit that should be addressed. If you’re working on some sort of a histamine allergy protocol. You’ve already hit upon increasing omega threes, your nuts, your seeds, your Coldwater fish, you’re doing your low histamine diet, if necessary, you’re treating the gut infections, but then boom, if you miss vitamin D, that’s easy.

Dr. Justin Marchegiani: 110%. And again, the other component, I would say is glutathione. We need that through digesting good proteins, right? So if we’re chronically stressed, let’s connect the dots here. So if you’re chronically stressed, you’re pouring out cortisol, your adrenals are in this fight or flight kind of sympathetic dominant state. You’re over secreted cortisol, and again, that can also look in a chronic state like low cortisol, right? Your cortisol doesn’t get low unless at some point it was chronically overstimulated. So some people think or feel like oh, my God, like my cortisol must be so my adrenal must be so overstimulated right now because I feel so off but it’s possible that they could be in this state of total dysregulation, and they’re on The lower side. So either way, chronic cortisol stress is going to affect your nervous system because the sympathetic nervous system is what’s engaged when you have a lot of adrenal stress. And the sympathetic nervous system affects digestion, right? It’s the parasympathetic that has the rest, the digest the energize, repair. So if we don’t have enough parasympathetics going, it’s gonna be harder to digest and break down our foods, absorb our nutrients. And this can really one start to create indigestion that can create more cebo and dysbiosis and bad bacterial imbalances. And those bad bacterial imbalances can negatively impact our immune system. And an immune system that’s not correctly primed. It’s overly sensitive and going after allergens that are not like a threat to us, that’s going to create allergy issues. So you see how this hormone adrenal Nervous System digestion, gut, immune connection kind of evolves, right? You can really connect it to a lot of different things because they really dovetail so importantly.

Evan Brand: Yeah. Now, the good news is, once you get the proper labs, it’s less overwhelming, because when you’re saying that back to me, I’m like, Oh, crap, how would somebody even know where to start with it? But once you get the data, it’s really easy for us to go and look at the piece of paper and go, Okay, look, here’s the gut analysis. Here’s the hormone analysis. And then on the gut analysis, we get a clue into the, into the hormones to right, because we’ll see that beta glucuronidation marker, if that’s high, we know Oh, crap. There’s recirculation going on. So this hormone profile now we have answers even deeper, we have a root cause of the root cause. Why is the hormone profile working like this? Well, because of the gut profile, and then you piece in the oats, your piece in the chemical profiles, the mold profiles, you look at where does somebody live environmentally, how much outdoor exposure Do they have, then we look at the diet piece, it makes it much much more digestible. So I just want people listening, you may be able to pull out little pieces of the puzzle like oh, I’m going to boost vitamin D, I’m going to do quercetin to stabilize it. But really, you got to get the data. So that’s what we always want to lean upon. for a couple reasons. One, it helps us to shorten the treatment duration, because then you’re not guessing and checking by just giving herbal anti histamines and sending people on their way. But number two, it’s a good compliance piece, because we can show people look, we have the reason of why you’re feeling like crap. Stick through this protocol, it works so much better. You know, there were times where clinically, I would talk to someone, and we would say, Well, you know, it sounds like this, it sounds like that maybe budget was a concern. It’s in a couple of cases. But we would just give somebody a guess and check protocol. But then we always had to go back to testing later. So really upfront, if you have this going on, get some data, so you know what you’re up against, you’re going to, you know, definitely shorten your timeline, and you’re going to shorten and decrease your cost. Like, if you were like me, I’d go buy this supplement, I’d buy that I’d buy that you have the supplement graveyard, you’re spending much, much more money doing that, as opposed to getting a dialed in protocol made for you.

Dr. Justin Marchegiani: 110%. Yeah, if you can see what’s going on is going to help you be a lot more compliant, for sure. And then one other connection here is we know that women who are overweight, they have twice the likelihood of having allergies as well. And again, I think this goes with men as well, when you’re overweight, fat is a major reservoir of interleukins, and cytokines and inflammation. So you can make a lot of inflammation via your fat cells. So the more inflamed you are, right? The whole thing with allergies and asthma and all these different things is the immune reaction that you’re having is an increase in cytokines and interleukins that are pro inflammatory, right. And so when you’re, you have exposure to endogenous allergens in the environment. That’s kind of what’s creating an anti inflammatory response. And then your body is then oversee accreting more inflammatory compounds, they kind of add to the mix, right? So your body’s overdoing it. And you have natural anti inflammatory compounds via cortisol and progesterone in your body. And if you don’t have enough reserves there to kind of let’s say, cover that up or neutralize it. It can really create more and more problems. That’s that’s a big one. I mean, here’s the summary. estrogens role in allergic disease remains complex, as allergenic as allergic disease continues to increase in the prevalence and effect women is fortunately gaining a fuller understanding of its effects. Basically, it’s talking about xeno estrogens and hormonal imbalances driving more allergy issue. It does it because it modulates the immune system, T cells, immune cells, B cells, it’s affecting all of the immune system, because we’re throwing a lot more histamine, leukotrienes and other immune compounds that are just putting our body into a more inflammatory state, if you will.

Evan Brand: Make sense i mean that once again, we’re back to external exposure, meaning potentially environmental but when we say environmental, that’s not just nature, it’s not like that anymore. It’s contaminated. You’ve got so estrogen.

Dr. Justin Marchegiani: Exactly estrogens may polarize T cells and cause more th to immune response that’s kind of more of our antibody immune response. So you may get a lot more of that. Estrogen promotes the class switching of B cells. To immunoglobulin e, IGE is going to be a product that those are eosinophils so it’s going to promote more in a more allergenic side of your immune system via eosinophils. And then of course, estrogen promotes the degranulation of mast cell base fill so base fills are in your blood their immune cells just like you eosinophils are when they start to go into your tissues, they can start they become mast cells, essentially a mast cells produce histamine and we know histamine increases all these leukotrienes and, and cytokines, which are part of this whole allergenic immune reaction. So you can see how all these things kind of, um, you know, roll downstream and create more problems. So when people are listening to this, and you’re like, what the heck is he saying, just focus on this just go upstream. Anytime you get overwhelmed, always go upstream. Okay. Everything kind of gets more granular and nuanced as you go downstream. So hormonal imbalances, imbalances and progesterone, estrogen, especially when you start to have more estrogen dominance, that creates more of a pro allergic response. When cortisol starts to go out of balance, typically, either overly high acutely or chronically low. In a more chronic situation, that’s going to create more allergies, the more your sympathetic nervous system is in fight or flight due to chronic hormonal stress that can create more allergies as well. It affects your ability to digest, rest, repair, and absorb nutrients, and it sets up your digestive tract for inadequate enzyme and acid levels. And it also throws off your gut microbiome start to have more dysbiosis and that can throw off your immune system. Why? Because 80% of our immune system is in our intestines are Gault which is our gastric associated lymphoid tissue, that’s our stomach and our mouth, our mucosal associated lymphoid tissue that’s in our small intestine. hope that makes sense.

Evan Brand: It does. So, if you’re still drinking out of single use plastic water bottles, you got to quit doing that, because you were you were reading through it kind of fast. But basically what I pulled out you were saying that these, you know, estrogens, those have been linked to stimulating or irritating the mast cells. Was that right?

Dr. Justin Marchegiani: Yeah, let me just read this summary here. This is a big one. So female hormones appear to play a significant role in allergic diseases, with estrogens effect being the most well studied estrogen influences, immune cells, favoring that th two immune response, and it causes our B cells or B cells are basically our body’s ability to make antibodies, right? We have five antibodies, right? neutrophils, lymphocytes, eosinophils, monocytes, basophils? How do I remember it? Never let monkeys eat bananas. Okay. That’s how we learn about that in doctoral school. And so we start to have a lot of these B cells, which you know, they can be anything of these five, they start to go more towards eosinophils. And again, he for allergy, that’s how we remember that he for allergy now with the exception is parasites can also increase the ascenta fills there for parasite infections can increase your chance of allergies to see all these things connect over. So the potential role for astron and nasm is supported by epidemiological evidence and increase the asthma prevalence and severity in adult women. And by associating estrogen with changes in airway mechanics and inflammation. However, the mechanism by which it may act is quite complex, we know that exogenous compounds of estrogen activity may influence allergic diseases, how well if we’re getting exposure to potentially birth control pills, or plastics, or pesticides, in the water, hormones and the meat all of these things may potentially throw us more into an estrogen dominant state. Now this study is not saying it, I believe it’s it’s really going to be that hormone ratio. So it’s more that estrogen dominance, unnecessarily high amounts of Astrid that definitely is part of it. But I think also that that ratio, or that Oh, right here, and it says with the effects dependent on the concentration of hormones, and the concomitant presence, or absence of factors such as progesterone, so it is kind of alluding to that the absence of progesterone can also throw that immune system into a more allergenic response, which is what I’m highlighting earlier, it’s more estrogen dominance than it is just estrogen by itself

Evan Brand: Makes sense. Okay. And now I’ve got a couple papers here is talking about estrogen is very stimulatory to the mast cells to release histamine. And then the excess estrogen also is going to down regulate the DA o enzyme that clears his domain Oh, bingo, they’re inactive. And at the same time, histamine stimulates the ovaries to make more estrogen. So the net result can be a vicious cycle of estrogen to histamine to estrogen to histamine, whereas progesterone comes in and stabilizes the mast cells and actually up regulates do production, and therefore can reduce histamine. So many symptoms of estrogen dominance are actually symptoms of histamine or mast cell activation. And then we know like mast cells, and histamine play a role in endometriosis and also pmdd. So that’s, that’s pretty cool. And this is an epidemic problem. You and I kind of talk about it. Like it’s this nuanced thing, but no, this is going on in hundreds of millions of women around the world and probably more so in women than men. But this issue can definitely happen in men also.

Dr. Justin Marchegiani: Yeah, so I don’t want men to kind of feel left out here. There’s a lot of men that have a lot of estrogen imbalance issues as well due to the environment, poor detoxification, gynecomastia excess of just being overweight, there’s some of those same mechanisms that are happening here, member fats can produce estrogens as well. So I don’t want our guy friends to be left out in this here. So just know there’s still a lot of the same mechanisms that are at play. Of course, we’re not going to be you know, hitting the hormones the same way. But we’re going to be looking at the adrenals are same way we’re going to be cutting out environmental hormones, we’re going to be looking at the toxification and your body’s ability to clear these excess of hormones. Of course, if we’re seeing women that come in with birth control pills, we’re going to try to hit that via a different mechanism. without throwing off the hormones, there’s a lot of ways we can hit this. I’m really happy that we’re talking about this because this is something that I see endemic in a lot of my female patients and male too. So I’m glad that we’re on top of this. And we’re not going to be going over too much on the supplement side cut for this because we talked about it last time. So please click down below and look for that previous podcast. But the big thing I would say with my female patients and or hormone patients listening is we’re going to look at potentially using endogenous progesterone, depending on the levels, we’re going to use herbs to help modulate estrogen and progesterone. So some of those herbs could be chaste tree, or maka or dawn quai. There’s a lot of other herbs that we use to modulate that we may use things like ashwagandha rhodiola, ginseng things to help modulate cortisol, of course, we’re going to be fixing a lot of the diet and lifestyle strategies, whether it’s blood sugar, inflammatory foods, sleep, of course, all of the healthy diet and lifestyle, things are foundational. So I’m not going to go into all of that, because that’s all with a podcast within itself. But just kind of keep that in mind. Those are all going to be part of the foundational principles that we utilize. And also I use other palliative things like natural anti histamine, the granulators, which looked at that previous podcast. And then also we talked about sinus flush protocols, and high quality air filtration, which are going to be important components. But you know, see that previous podcast for more instruction on that.

Evan Brand: Yeah, well said last thing here, just a note, it was talking about the whole progesterone, estrogen mast cell connection. And why progesterone, of course, is going to stabilize mast cells and upregulate DAO, and it made just a note here. This is why most women feel better early in the luteal phase when progesterone is higher. So if there is like a cyclical pattern to your issues, pay attention to your cycle. That’s probably a good clue there that it is progesterone deficiency.

Dr. Justin Marchegiani: Yeah, part of the reason it wouldn’t feel bad those last couple of days or a week before is because that’s where we have the biggest drop in progesterone. So it’s this big drop that happens. And usually it happens a little too early. And that’s what kind of gets this whole cascade of PMS or pmdd happening, right. And it’s usually just that fall out and progesterone too soon and too hard. Usually around a 21 to 24 it can just fall out harder versus gradually coming down around day 27 or so.

Evan Brand: And you’re saying we can help blunt the drop with some of the strategies, the herbs and nutrients, getting rid of the excess estrogens in relationship all of it.

Dr. Justin Marchegiani: Yep. And don’t get me wrong. utilizing some of these natural anti histamines that we talked about in podcast one is helpful. But we just have to always draw a line is this the root cause and so I always want to make sure patients know this is not the root cause, but it’s buying us time. And it’s helping us deal with the histamine while we work on all the other diet and lifestyle and hormonal things. And then over time, you become less reliant on those things. And it’s better than taking medications that cause you to be drowsy and brain foggy throughout the day, or even things that add more steroids in your body to which could be more destructive. 

Evan Brand: Absolutely. Well, if you need to reach out and get help, please do. If you need to reach Dr. J, you can at his website, JustinHealth.com. And he does console’s worldwide via phone, FaceTime, Skype, whoever you need to reach him. He’s there. If you need to reach out to me my website, EvanBrand.com we have all the information in regards to scheduling. It’s a piece of cake and you can book a intro call to discuss your symptoms, your goals, see if you’re a good fit for care, we’d love to help you out, get you off the roller coaster get you off the merry go round, unless you like that kind of thing. But these medical merry go rounds are not something fun. So we want to try to get you off of that.

Dr. Justin Marchegiani: Totally. I have three patients this last week. Two women, one man, one man who had a significant 80% reduction in lifelong allergies, doing a lot of these strategies. So I mean, these things aren’t esoteric, like there’s a lot of thought leaders out there that just talk about things, but they aren’t in the clinical trenches with their sleeves rolled up dealing with people working on this and actually getting results. So you know, I have quote, I have, you know, strong experience in this Evan does too, and we’re seeing it so when you guys are hearing the things we’re talking about this isn’t theoretical. This transcends what you’re reading the study. This is real. So I don’t We say that just to give you guys a lot of motivation and hope that if you’re listening, just start applying it. And then if you’re feeling confused or overwhelmed, we’re here for you. There’ll be a link down below where you can click to reach out to us and we’re here to help y’all. And if this information resonates, please find a family member or a friend that you can share it with because we really appreciate that.

Evan Brand: Awesome, we’ll take good care. We’ll be in touch next week. 

Dr. Justin Marchegiani: Have a good chat with you have a good one, y’all. Bye now. 

Evan Brand: See ya. Bye.

References:

https://justinhealth.com/

https://www.evanbrand.com/

Recommended products:
Allerclear Histamine Support
Nasaline Sinus Flush Bottle
Xlear packets
Xlear rescue spray
Navage Nasal Irrigation
NeilMed Sinus Rinse Complete Kit
Xlear Sinus Rinse Kit
Austin Air Healthmate Plus
Air Doctor Air Purifier
Whole House Water Filter
Water Filtration Devices
Clearly Filtered

Audio Podcast:

https://justinhealth.libsyn.com/the-allergy-and-hormone-connection-natural-allergy-solutions-part-2-podcast-314

Natural Strategies to Help Relieve and Support Your Allergies | Podcast #313

Some people with allergies may find relief by using natural plant extracts and foods that will act as antihistamines. So in this video, Dr. J and Evan Brand talk about allergies and natural and functional medicine approach. 

Dr. J and Evan recommended initial things that can help you manage stress. Stress hormones wreak havoc in the body, especially in the immune system, making seasonal allergies even worse. Consider stress management methods such as meditation, taking time out for self-care, and avoiding over-committing your schedule. Constant house cleaning can get rid of many allergens and help relieve your symptoms. 

Often, allergies will get worse by toxins within our body. The liver is a great negotiator of inflammation in the body, and when it is working overtime metabolizing our stress, alcohol, medications, and processed foods, allergies can flare up. Detox your body by eliminating fried foods, sugar, alcohol, and other toxins from your diet. For more detailed steps and solutions, don’t miss out on the full podcast to fix or avoid allergies!

Dr. Justin Marchegiani

Dr. Justin Marchegiani

In this episode, we cover:

0:36       Conventional Approach on Allergies

7:49       Getting the Diet Dialed In

12:54     Gut Infections Connecting to Allergies

16:08     Air Purifiers

20:30     Natural Supplements

30:29     Low Histamines

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Youtube-icon

Dr. Justin Marchegiani: Hey guys, it’s Dr. Justin Marchegiani here with Evan Brand. Today we’re going to be talking about natural solutions to help relieve and support your allergy springtime is officially here. It’s like the last week everything around my home has been blooming, it’s been amazing. Love that feeling of that transition from winter to spring. So that’s really exciting. But with that comes a whole host of other challenges with allergies and sinus issues and headaches and, and runny nose and itchy eyes. And we’re going to talk about natural solutions that we implement with our patients clinically in real life that actually get results, not just you know, stuff you read in the blog post, but real stuff. Evan, how are you doing, man?

Evan Brand: I’m doing pretty good. Why don’t we talk about the conventional approach first, I think it’s good when we do that comparison and that contrast for people. So you go down the street, you see the Joe Blow allergy clinic, you’ll walk in, they give you some type of medication and you go home. And that’s pretty much as far as it goes in regards to treating allergies. And you know, they have different options. I know some people get shots. I know some people do nasal spray, some people do anti histamines orally. So there are several options. But they all have the same goal, which is really just a band aid. It’s trying to block receptor sites maybe decrease inflammation somehow from a drug perspective, but it’s not addressing the root cause of the allergies in the first place. And I’m not going to speak for you but my opinion is that allergies are a side effect. Humans have been outside for forever. And now all of a sudden, we can’t tolerate the outdoors and we need drugs to manage us to handle the outdoors. That’s not natural. That’s not primal. That’s not ancestral. I don’t think that there is an ancestral allergy. I think this is a new problem based on the toxicity of the planet, but also other issues that we’ll get into in regards to the internal health of the human host.

Dr. Justin Marchegiani: 100%. So, if we talk about some of the mechanisms of how these medications work, I think that’s helpful. Right? So there’s a bunch of ones that are out there. So you have things like Allegra, right or Claritin, I think they work the same way. They’re kind of like an h1 receptor. They’re they’re like an anti histamine and they weren’t they antagonize the h1 receptor. So there can anti histamine, right? I think Pepcid AC also works, I think on the h2. So you have anti histamine ones, whether they’re Allegra or Claritin, they tend to be more on the anti histamine side. Zyrtec similar as well. They’re a h1 blocker. They’re they blocked the h1 receptor as well. And so you have a lot of the anti histamines the problem with those is they come with a lot of side effects like drowsiness, right, drowsiness, brain fog, cognitive, low energy, so not good. If you have to perform, you have to function you have young kids, right? Most people have to be on it, you know, at 100% to be functioning in the daily life. So that doesn’t really work too well. And then you have more advanced things like I want to say Singulair would be one that would be more anti histamine based, there’s, I’m sorry, more steroid based, more corticosteroid based. So there’s ones that are more steroid based, or people that have, you know, more significant allergy, whether it’s throat closing or needing an inhaler, of course, then you have things like albuterol, that may get worse, right. And so these are, you know, the steroids tend to get used when there’s more advanced allergies. And then of course, you have some of the allergy shots, which tend to be a little bit more natural, which tend to be exposing yourself a little bit to the allergen as a way of kind of building up an immune response, that’s not going to be over responsive com that allergy season, those are some of the big things off the bat. And I think you want to highlight Evan?

Evan Brand: Well. I want to highlight the fact that billions and billions of dollars are being spent per year globally with people being on these medications. And it really gives them a false sense of security, meaning, yeah, it might help the symptoms. But this is not getting to why someone is unhealthy in the first place. And I could go down a whole rabbit hole with this. But I mean, just because you get a shot for something, and now you feel a little bit safer. Well, you didn’t under you didn’t address the underlying issue with your histamine intolerance in the first place. Is there a gut issue going on? Is there some sort of imbalance with your gut bacteria, you have a lot of histamine producing bacteria, are you eating a lot of food allergens and your bucket is already so full of allergens, the now the outdoor flower blooming puts you over the edge See, if everything else in your quote bucket is not filled, you should be able to tolerate the outdoor environment just fine. And so I think we should mention mast cell issues. mast cell activation could be triggered by mold. It could be triggered by Lyme it could be triggered by co infections like bartonella babesia. And you’re definitely going to have a lot more issues. Now. I’m not somebody that would say I have outdoor allergies, but I have felt a little different with everything blooming. And I’m just doing my herbal anti histamines to help which we’ll get into but I know that there was an underlying trigger, because for my whole life 30 plus years I haven’t had allergies. And now I feel a little weird a little spacey when everything’s gloomy. So now I’m like, oh, okay, my buckets full from these other things. So all I’m saying is, I just want people to really focus on the whole picture. have their whole health. And if you have allergies, that’s just the warning light or the check engine light on your dashboard, but there’s probably something else under the hood going on that you should address because there might be other issues that are downstream that you don’t even realize are related like allergies and diarrhea, allergies and constipation allergies and insomnia, allergies and anxiety and panic attacks and heart palpitations and blood pressure issues and skin issues. I mean, we could go on and on about how allergies is just one piece of this whole puzzle.

Dr. Justin Marchegiani: Yep 100% and then just to kind of recap here I made a mistake here Singulair is not a corticosteroid essentially is blocking luco triangles, which are kind of going to be an immune response from the leukocytes. So some of the allergy medications that are going to be on the steroids side that’s gonna be like Nasacort, Nasanax, Flonase will be another Rhinocort, [inaudible], those are going to be more of the steroid options which are going to be more severe. Then you have the leuco trying blockers right which is the Montelukast sodium, which essentially is the Singulair and then you have the h1 receptor site blockers or antagonist. And those are going to be like your anti histamines, right? That’s gonna be like your Allegra, your Claritin, right, your Zyrtac, those are going to be more on the anti histamine side. And some make you drowsy, Allegra may not as much. But in the end, like you mentioned, Evan, these medications are not getting to the root cause, especially if you weren’t born out of the womb with allergies. This is not something that’s something that’s developed over time typically, because your antigen bucket or your stress bucket has been filling up over time. And diet plays a big role. The more inflamed your body is, the more inflamed your body is, the more your immune system will over respond to allergens in the environment. It’s kind of like the more inflamed your back or your joints are. Something very simple like going for a walk may inflame your near back. But we know a walk generally speaking shouldn’t be in flaming your near back, right? So it’s not a proportional response. Same thing with allergies, it’s not a proportional response, your body shouldn’t be responding to allergies, like it’s a virus or some bacteria in the environment it shouldn’t be. And so the first thing we have to look at is what are the big stressors in your stress bucket out of the gate. So the first thing we look at is diet. One, the solution to pollution is dilution. Are you drinking nice, good clean filtered water with extra minerals in it? Are you eating kind of an anti inflammatory diet, a good paleo template, we’re keeping grains and refined sugars out. And especially if you have allergens, dairy and grains are big ones. And you may have to cut out nuts, seeds and eggs as well is a good one out of the gates where you’re focusing on healthy meats, healthy vegetables, dialing in the carbs, according to you, and then also having healthy fats that are going to be away from the process vegetable fats as well as gonna be a good thing out of the gates. 

Evan Brand: Yeah, and we’ve seen people have significant improvement just by getting the diet dialed in. I mean, I’ve heard 50 60% improvement with allergies just by eating clean, people that were eating gluten for breakfast and dairy for lunch on their salads, you know, doing the ranch dressing and their bread crumbs and all that crap and then we get him eating clean and all of a sudden the allergies are better and people that are either reducing their medication or they’re able to completely get off their medication, which is a big goal. For a lot of people they feel dependent and they feel scared like well what if I travel or what if I go somewhere and I don’t have access to this medication? You know, they feel the same way they do about their eyeglasses. What if I break my glasses when I’m on a desert island and I can’t see people feel that way about allergy medication they feel very afraid to to try to live without it because they know how they’ll respond. The good news is it’s possible that you don’t need it if you can fix all these other issues.

Dr. Justin Marchegiani: And histamine is basically an immune response due to these allergens, right allergens are just foreign antigen, they’re their foreign proteins or compounds in the environment, whether it’s dander in Austin cedars really, really big this time of year, you can see like literally you go on the parking lot to coats the cars, you know this, this yellow cedar. So the first thing is, make sure all the diet and lifestyle things are dialed in. The next big thing, especially if you’re outside a lot during the days, is most people’s sinuses are full of these allergens and dander and pollens and so a good sign is flush protocols and the bee Bay. So during allergy season, morning and night is going to be essential. If it’s really acute, you may do morning, midday and night but morning and night, you want to be able to go to bed with a clean sinus and you want to wake up with a clean sinus. You may even want to do it when you’re at work as well or when you come home from work especially if you’re inside for the day like around six, seven o’clock, maybe do it then so you can get some relief. And of course we’re doing a really good sailing or a high quality filtered water or a distilled water solution. We’re going to be adding in some sodium bicarb and some minerals. So it’s pH balance so won’t irritate the sinus mucosa. If you just do a whole bunch of water up there and it’s not balanced, it could really create irritation. So make sure it’s balanced with minerals. Now we’ll typically do some things that have Xylitol in there, which is very good at breaking up bacterial biofilms and also have some antifungal qualities. So that’s wonderful. I’ll do two to three seconds of flow down each nose blowing in between. That’s wonderful. I’ll even chase it a before with a spray called Xlear rescue spray. It’s wonderful because it has about six different herbs in there, parsley and pati arco and all of oregano, and they’re gently diluted in the pH balance water with some saline. And so I chased that up because as an antimicrobial anti biofilm effect, and then I flush it out each sinus and you can do like a good sinus irrigation bottle is Sinusgator, there’s, there’s the Nasaline, there’s the Neomed bottle, the Xlear bottles, you just type in sinus irrigation or sinus irrigation bottle on Amazon, I’ll put the ones that I like below. If you go to my site, JustinHealth.com/shop I have a recommended list of all the things that I use, Evan does as well. And so take a look at those and we’ll kind of have recommendations below in the link so you guys can see it. But the first thing is get the sinuses flushed out get the crap out of the sinuses, if it’s sitting there for six or eight or 10 or 12 hours, it’s gonna create inflammation. So the first thing is flush it out. And if it’s really sticky, or like has a hard time flushing, you know, use some of those biofilms to break it down. That’s kind of my first recommendation out of the gates there. And in preventing these things from brewing.

Evan Brand: Yeah, that’s great. And the rescue is intense. So if you’re, if you’re like super inflamed, take it easy. I love it, though, it feels amazing. And then also, we like silver too. So we will use some professional, we’ll use some professional professional version of silver, we call it Argenton. And that one works great. So I like to do both, I’ll do a little bit of the essential oils. And then if we think there’s like a more colonization issue with mold or something like that in the sinus, we’ll use the silver. And it can be very, very helpful. And I just want to make a note to people because I was one of those guys who said, Well, I don’t have any sinus problems, because I never had any runny nose. I never had like what I thought was a stuffy nose. Like I could breathe fine. But man, when I started doing some of the sinus treatment and these protocols, whoa, I realized I had like 30% more breathing capacity. I’m like, Whoa, I mean, I really opened all this stuff up. I didn’t know it was bad to begin with. So if you’re one of those skeptics like me, who’s like, Oh, I don’t have sinus problems, try it and see what happens. You may feel that you can breathe so much better.

Dr. Justin Marchegiani: Oh, yeah. And especially if you’re like you got young kids, because I you see it with young kids all the time. I have young kids, you’re their friends or whatever they’re hanging out with, they got runny noses, like non stop all the time. And I’m like, yeah, your kids probably got a little biofilm colony up there and need to work on flushing it out. Because the more that’s hanging up there. So anytime we see a kid, you know, our kids with chronic runny nose for a day or so we’re flushing that thing out within a day or two, we’re not going to write out and that works phenomenal. And then you can also use things like n acetylcysteine, to dry out those sinuses to which can be very helpful. So there’s a lot of mucus you can dry it out with the NAC, which is excellent. Very, very good out of the gates.

Evan Brand: Yep. So let’s talk about the guts. I want to hit on some of the gut infections. And we hear Justin’s cat if you hear me out. That’s his cat.

Dr. Justin Marchegiani: I just gave him a little kick under the table, like “get out of here!” 

Evan Brand: Maybe he wants some sinus rinsing. I know. So Oh, God would be terrible. No, no, that’d be impossible to do. Alright, so let’s let’s hit on the gut. So because this is this is a big deal. And I’ve had many, many, many, many people with histamine and sinus problems say that the single biggest thing they’ve ever done beyond the sinus rinsing and the actual coat allergy treatments was actually just fixing the gut. And I believe this is because of all the histamine producing bacteria that we see and all these bacterial overgrowth cases. So if you’re coming to work with us clinically, what we’re going to be doing is looking at your urine and looking at your stool to be looking for different infections or imbalances. And the good news is when you use herbs to rebalance all these bacteria, now you’ve drained the bucket so much that you can handle the outdoor environment. And so in fact, even some of the reviews on some of the products we use that people will say, hey, these herbs cured my histamine intolerance. And we did nothing with the sinuses, we did nothing in the quote, allergy realm, we simply fix the gut. So I don’t want people to ignore that. That’s why I was saying I was a little frustrated in the beginning because people will go to the allergy doctor and they never bring up the gut. They never bring up the diet. They just don’t even have a clue.

Dr. Justin Marchegiani: 110% So, so the first thing is, it’s like get the inflammation down in your gut. That’s going to be food. Excess refined sugar, inflammatory foods, junky omega six process fatty fats, which are going to be like soy, canola safflower, right if you’re going to do any plant based fats, coconut oil, olive oil, avocado oil are going to be better some palms gonna be great. animal fats are going to be of course awesome. And then if you can tolerate ghee or butter, great if you have allergies out of the gates pull those out because those can be mucus forming. I always say get your allergy straight in and make those one of the first fats you add back in and see how we do because if we can handle it, I want you to handle it. I want it in There. And the next thing after you have all the food stuff dialed in, and then you’re doing sinus irrigation. I like doing the rescue spray first because it is intense, like Kevin said, so then I put it up there and I chased it with some saline behind it, therefore it flushes it out, cleans out antihistamine, anti inflammatory anti histamine benefits. Because the problem with allergens up the nose if you’re outside, and then you come back inside to a nice clean home, even with awesome air filtration, which air filtration is a huge, important component to this. You’re still breathing all this dander and pollens up your nose all day long. That’s why you got to flush it. And that provides the relief from those allergens. And then of course, we want a really, really good air filtration. So Evan and I are big supporters of the Austin Air healthmate plus, which is good as a couple. They have an allergy machine too, but I think the healthmate Plus is the best out of all of them. Because of the charcoal, the zeolite. It’s a bigger filter last longer. And then it has the potassium iodide coating which filters out the volatile organic compounds, the voc’s which are going to get in mattresses and paints and new furnitures and that’s an extra allergen that could be adding to your histamine bucket as well.

Evan Brand: Oh yeah, speaking of air purifiers, I’ve got a cool update for you here. I’m going to see if I can load the email from one of the head honchos at Austin. Because I wanted to ask them about aluminum nanoparticles, you know, they’ve done some air sampling of what people call Kim Trails. Meteorologists say it’s conspiracy, and it’s a contrail. It’s just exhaust vapor. Don’t worry about it, even though Bill Gates plan just got shut down. They were gonna do the solar blocking, basically, anyhow. But this plane flew into these trails and tested and found that it has aluminum nanoparticles. So long story short, I asked our guy at Austin, and I said, Hey, hoping to find out if this air system can filter aluminum nanoparticles. And the guy who did analysis on the trails in the sky, he found that the aluminum was around 400 nanometers. And the guy said, Yes, four nanometers. 400 nanometers equals point four microns. And the Austin filters down 2.3 microns at 99.97%. So now Yes, our filters will handle this. No problem at all. So whether or not you believe the geoengineering thing is going on whether you simply want to filter, the allergens plus the stuff out in the sky, either way, you’re covered with the Austin and so contact our office if you want to get ahold of Dr. J, or myself, and we would love to help you. I’ve got one right here in my office, and it runs 24 seven. And I wish you could smell the air in here. Because it smells like nothing because it’s so pure.

Dr. Justin Marchegiani: I 100% agree. Like there’s a lot of controversial things that are out there. But here’s the deal. If we just talk about the things that we know, which we know, pesticides are out there, right? We know you have voc’s in your home from paints and that new couch robot and the new furniture. We know that there’s allergens out there. We know this potential smoke, especially if you’re in certain areas in California and the west coast where there’s fires throughout the year. We know those things are part of your stress bucket. And they’re they’re a part of that antigenic load. So you want to at least filter them out. And if we have other things, you know, aluminum salts, and Berry and other stuff going on there great. You’re also going to have benefits from that as well. So want to make sure that’s clear. The goal is to decrease all the stress bucket and you’re going to be inside sleeping eight hours a day, you’ll probably be inside at least 12 hours a day on average. And most people with the environment and the world that today we’re while people work from home. And so having super high quality air is incredibly important. super high quality water is very important. And then having very nutrient dense anti inflammatory, low toxin food is foundational. And then after that we can kind of talk about natural anti histamines and things to help kind of dry up sinuses. So I like NAC. I like propylene I like quercetin. I like stinging nettle. I also like things like potassium, potassium bicarb. I also like things like kidney glandular and D A O dia mean oxidase. My plug here is a product called Allerclear which has some of these things in it. I know Evan has a allergy product as well Evan, what’s yours called?

Evan Brand: Histamine Support.

Dr. Justin Marchegiani: We’ll put the links down below. So if you guys are enjoying the content and you want to support the show, feel free and purchase that from us. We appreciate it. We’re only recommending things that we recommend for our family and friends and patients. So those are helpful. Now again, I always draw a line like okay, what’s conventional medicine doing? Zyrtec? Allegra Singulair? Nasacort, right? We already know they’re like anti histamines h1 antagonist, steroids, right. luco trying blockers. That’s the mechanism over there on conventional medicine, which we know has more side effects right. Now, especially with the steroids, that’s a big one that can stress out your adrenals and create blood sugar issues and potentially can create issues with joint loss and bone loss.

Evan Brand: Let me add one thing before you ever get before you move on. So another mechanism that makes you actually worse and more dependent on those medications is that a lot of those conventional medications Actually down regulate or deplete your body’s do production. So now you’re even in more trouble. So you mentioned da o and you and I like to use that. And that helps with the ingested histamine. Meaning if you’re going to eat a high histamine food, we can give you supplemental do extract, and then that’ll help degrade the histamine coming from your diet. However, if you’re on those medications, you’ve now drained your do and you’re likely going to have more histamine intolerance, digging yourself even deeper in the hole. So I just wanted to add that in while you’re hitting on the comparing.

Dr. Justin Marchegiani: Yes, yeah, so we have conventional on this side. And then we have like all of these natural things, supplements that I just mentioned, quercetin bromelain do now these are better. These are much, much better, less side effects. Some of them are going to be our actual nutrient base like glutathionr building blocks, right, really helpful there. Potassium, super helpful. Kidney glandulars, da L, but a whole bunch other B vitamins and b, 12, and vitamin A. So those are actually really good. But I urge you, right? Don’t just listen to this and say well, I’m going to trade my Zyrtec for kidney or Dr. J’s Allerclear, try to actually make root underlying changes. If eating a whole bunch of grains and dairy and sugar, try to focus on the root cause stuff. Or if you know you’re outside a lot, and you’re not doing sinus irrigation, or you don’t have air filtration, try to get the external environment in your home, external environment in your sinuses and your internal with your body fix first, if you can. Now it’s okay if you go to the supplements at some point, but try not to go to them first, because then we’re just kind of acting like conventional medicine. Even though these have less side effects. Like Evan mentioned, they don’t deplete do some of them build it up. And some of them also have nutrients. So still better. But we don’t want to replace palliative care, which is supplements, we want to get to the root cause as well. It’s all about getting to the root cause.

Evan Brand: And it’s very simple. But I hope everyone is at least taking their shoes off when they enter their house. I mean, what a simple way to reduce bringing in oil and gas and pesticide herbicide who knows what else so you know, if you’re not already take your shoes off before you come in the house. And then if you have any carpet, so there, there are some carpet cleaning solutions that we use that are essential oil based, where if you had a pet, for example, that brings a lot of stuff in from outside, and that’s irritating you you can rent your carpets with this cleaner. And then also laundry solution, we do have some essential oil laundry solution that we use. And that will actually help to treat mold and pollen and all that on your clothing. So if you’re out like rolling in the grass, which is fine, you might want to just treat your clothes a little bit to make sure that they’re okay, but what let’s go back into the supplements because you were hitting on some good stuff. So also, in some of the products you and I use is vitamin C and vitamin C can actually help degrade the histamine. It’s amazing. My body.

Dr. Justin Marchegiani: Yeah, so essentially there is like anti histamine to granulators they help break the histamine down. Okay. And then there are essentially anti histamines they have natural, they decrease the production of histamine, right. And then we have the DA o enzyme support which does kind of also help degrade the histamine down as well, right because da o dia mean oxidase helps break the histamine down. Like Evan mentioned, a lot of the medications deplete the eo so they actually create long term dependency on it. It’s kind of like people that have proton pump inhibitors or acid blockers, well, it creates more problems because you’re not breaking down your proteins, your fats and your amino acids, therefore you have more issues down the road with other symptoms, right? Got to get to the root. And then Evan kind of alluded it one big other, let’s say, antigen, antigen or compound that goes into that stress bucket is if you’re if you’re washing your clothes, or your sheets, or your laundry with dryer sheets, or any fragrance laundry, no bueno. That’s a big, big thing. If you’re just conventional, at least get the like I like the all free and clear. That’s a good one that’s like dermatologist approved for like eczema and like chemical sensitivity that’s at all major stores. So you can always get the all free and clear. You can do seventh generation free and clear. There’s a couple of other brands that are out there that have just essential oil based no sense no nothing like that. That’s ideal. And ideally, no dryer sheets. And if you need more support to get extra odors out. There’s baking soda is a baking soda company makes one called wash soda wash soda, essentially baking soda for your laundry and it’s got ammonium or pseudo it’s got sodium bicarb in there and it just sucks out any mold or kind of like more pungent smells in your clothes. And so if you need that, that’s a great way to kind of get your clothes and your laundry clean without extra chemicals and crap in it.

Evan Brand: Candles. I mean hopefully I don’t have to beat the drum on this too hard. Hopefully you and you all listening have heard enough of us talking about this. But for anybody new. Please get the synthetic fragrances out of your house, you’re destroying your hormones. You know, man, you’re affecting testosterone and estrogen and women Same thing for you. So any Glade plugins, air fresheners after you poop, turn the exhaust fan on and use essential oils if you have a nasty smelling poops. You know you don’t need to be using synthetic toxic chemicals because that’s filling up your bucket. Then you’re using Pine Sol to clean your floor. So make sure your floor cleaners are legit. And those are clean. Make sure all of the cleaning chemicals you’re using are clean, seventh generation or branch basics. There’s so many good brands now there’s no excuse to not use clean products. When you’re cleaning your dishes, make sure you’re not using synthetic fragrances in your dishwasher. You can use free and clear for that, and your hand soap, your shampoo, your conditioner, your deodorant, everything needs to be cleaned, because you’re just filling up your bucket. If you’re exposing yourself to all that garbage. Now, you could do all that stuff and still feel bad. So that’s where we come in and do some of the functional testing to assess your gut. We’ll look at mitochondrial function, we’ll look at neurotransmitters amino acid metabolism, fat digestion, there’s so much that we look at from the testing perspective, we’re just giving you some good strategies today that can help but there still is a deeper layer that we need to investigate. And that’s where we come in.

Dr. Justin Marchegiani: 100% out of the gates. And so just to kind of highlight a couple of things there. You talked about the gut. That’s important. h pylori, fungal overgrowth. SIBO can create stress in the gut that creates more histamine. Imagine that histamine bucket filling up. So as you mentioned, gut issues create a lot of inflammation like a lot of these mast cell issues even like mast cell, Mass cell, right? mass cell activation disorder, right? Well, that’s just a sign that you’re inflamed and your immune system is spitting off histamine got to get to the root underlying issue. A lot of people talk about things like it’s the cause, but they’re really talking about the effect, right? Oh, my arthritis, my arthritis. Well, that just means you have an inflamed joint. What’s the cause of that, though? Of course, we know that’s the effect, right? inflammation in that area pain, right? We know that’s the effect, right? But what’s the cause? Right? So you have to always say most people in conventional medicine and even natural medicine, get people talking about the effects, but don’t address the cause. So make sure if you’re labeling anything, it’s only worth labeling something if you can connect it to a cause. If not, you’re just describing the symptoms that are presenting itself, which aren’t hard to do.

Evan Brand: Agreed. So yeah, if you were diagnosed with like a mast cell, or you suspected like masel activation m casts for short, you got to get to the big triggers. I talked about that in the beginning, mold, bartonella, Lyme, babesia, any kind of like tick borne issues, mosquito borne issues, vectors like that, they can aggravate your system and can cause you to be more allergic. So you may have to treat those things. I know, for me personally, you know, I know that just treating Lyme and co infections has made me feel better with some of my reactions. So you may need to dig a little bit deeper. And that’s really where you want somebody on your team because just trying to do this alone. It can be challenging, and you’re going to end up with a supplement graveyard and buy stuff you don’t need. So yeah, the herbal anti histamines are great, but what led you to need those in the first place? That’s, that’s the question need to ask. 

Dr. Justin Marchegiani: And I agree. And I can tell you like, there are some low hanging fruits that can do amazing things I’ll give you Case in point I had one patient, literally before me went to Mayo Clinic. She had chronic sinus issues. They’re literally telling her that, that that’s it like she asked she needs she’s already did surgeries didn’t relieve it. They’re telling her I think she can do just cut out cut out simple things like grains, her sinus issues were gone. And Mayo Clinic literally told her, there’s nothing she can do. She’s already on the surface, nothing else they can do all the medications, we just kind of grains gone. It’s like what it was that easy. Like, sometimes you have to kind of shake your your like, you kind of have to like, you know, give yourself a little wake up because you think oh, you’re gonna have to go into some elaborate protocol, and sometimes simple foundational things, move mountains, and you’re like, how did that happen? But that’s why we kind of have our checklist in our flowchart. And we don’t ever skip things no matter how elemental or easy. It seems like it would be it can move the needle sometimes.

Evan Brand: Yeah, now and I would just totally repeat that in a different story. You know, a lot of people, even practitioners like you and I, we could easily get lost in the weeds, we could go down these complex rabbit holes, and then we can lose sight of the foundations. And I see a lot of practitioners doing that part partially due to marketing, right, they have to become the thyroid guy, they got to become a guy. So so they’ll skip over foundations because it doesn’t fit into their brand, which is totally stupid. But my story is I had a female client a few weeks ago, and she just had extreme shortness of breath. And she didn’t know if it was like post COVID or what it was. But anyway, we looked at her ferritin on her bloodwork, and all the doctors had been like 20 doctors, her ferritin was seven. Oh my god, forget you. And I know. I mean, if you’re less than 20, you’re not going to be able to catch your breath. So we started to boost up her ferritin. But in the meantime, based on everything else during the initial call, I thought it could be like a histamine problem as well. So I said why don’t you just I’m going to give you this low histamine God, I want you to just eat low histamine until we get your labs back. When we did the lab review call. She said that it was 90% better. She said that within 48 hours of going low histamine. She was at least 50 to 60% better with her breathing. She could barely catch her breath while we were talking. She could speak in full sense It says without having to stop just just doing the lab review. I’m just pointing out, we didn’t even get to look at the data yet. Just a low histamine approach was enough to get her better. So this is in your allergist is not I’m sorry. I mean, if you’re an allergist out there and you’re prescribing low histamine diet, please email us, maybe we’ll do a podcast with you. But I don’t think this is happening. And there’s people sitting somewhere in an allergy room, an allergy office clinic right now. And they’re going to go home with the medication and they’re not going to learn a single thing about low histamine diet.

Dr. Justin Marchegiani: Exactly. And I agree, sometimes low histamine needs to be added on top of maybe our paleo or autoimmune thing, and I have a handful of patients right now where I had to go to that tool. And it can work amazing now that what are low histamine, paleo foods that are pretty common, any of your age meats, so like bacon, those kinds of things, pepperoni, salami, even if it’s pasture fed, or organic, your citrus fruits going to be a big one, sometimes your nuts and seeds. And I would say sometimes your fermented vegetables and your fermented drinks, even if you’re like, Hey, I’m, I want to get my probiotics and naturally, that sauerkraut or that kombucha may be a problem. Sometimes you have to go and pull that out. And so that’s, that’s a big thing we have to look at. And then also, sometimes mold in the environment could be a big thing. Now, I don’t go there first, because there’s too many other things that typically have to go there. So we’ll add that to our list. And especially if we have visible more for sure. But if people are feeling better coming back in their home, that’s usually a good sign. Most people with allergy season this time of year, it’s a punctuated response. And they really feel worse when they’re outside. That’s when you kind of know that it’s probably more environmental than not, if it’s just mold inside normally, it’s an all year round kind of thing. Would you agree on that, Evan? 

Evan Brand: Oh, yeah, I would agree. Yeah. And with like, our air purifiers and everything, I know that I feel significantly better when I’m in my house. Yes. So to me, I’m like, Okay, good. We I’m kind of the canary right. So I can pick up on things. And so I think if people are in tune enough, you should know, like, if you’re out at the store, and you’re outside, and then you go in your home, Do you get any relief? If not, then your home could be a contributing factor. And we can rule that in RL.

Dr. Justin Marchegiani: Exactly. And then of course, the good scientists irrigations wonderful, we’ll put links for that below. We talked about the diet, talked about food, we talked about supplementation, we’ll put links for everything. And then outside of that, hormones do play a valuable a very important role. So women with chronically low progesterone and people with low cortisol, in general, these are kind of natural anti inflammatory hormones. If they’re chronically lower depleted, they can affect your immune system. And so again, we know medications like nasal core, if you destiny, they’re steroids, right? And so they’re giving you steroids to kind of help with the inflammation of the allergens. And so we know if your natural steroids are incredibly lower depleted over time, for many reasons, we mentioned already, looking at your natural progesterone, your natural cortisol levels may play an important role. So taking a look at the adrenals taking a look at the female hormones, especially right around day 20 or in the luteal phase or so is very important. It plays a very important role.

Evan Brand: Good call. I mean, we could probably do a whole part two on that the adrenal allergy connection. Yeah, totally. I know. adaptogens helped me feel better. So I don’t even think we fully understand adaptogens and how they may help with stress response, but they may help with allergy response to I mean, there’s definitely a really cool, yeah, yoked up a whole new can of worms there. So I know. 

Dr. Justin Marchegiani: We’ll leave it at that we may want to do a follow up on this the hormone allergy connection that maybe we’ll save that for another week coming up?

Evan Brand: Well, I hope people enjoy this as much as you and I do. I mean, just listening back and trying to like, listen to our conversation. As an outsider. I’m like, wow, this is such amazing information. And you’re not hearing about this. So I really hope that you guys listening will share this with your friends, your family, and review us go on your Apple podcast app. That’s the best place to review us. And look at Dr. J show. Look at my show. And just click five stars. If you think we deserve it and give us some words, give us some words of affirmation. Tell us what you think. Because this really helps us. And we don’t have to do this. We just love doing it. And we love sharing with people. You know, we get hundreds and hundreds and hundreds of 1000s of people listening per year. We just love it. And if we can just put a dent in the world and make people feel better than our job is complete. So please, sharing is caring. And if you need help clinically, you can reach out to Dr. J he would love to help you with these issues. The website is JustinHealth.com. If you’d like help for me, my website, EvanBrand.com has all the info. You can book free calls with our staff and talk to us about your symptoms, your goals, what’s going on, we’ll see if you’re a good fit for care and take it from there.

Dr. Justin Marchegiani: Absolutely. And we appreciate you guys for you know sharing everything and, and writing some good reviews and putting your comments down. It helps keep us inspired and it gives us more ideas of future topics to write about. So put your concerns on there. make notes and things you want to hear about as well love to see it. And that’ll give us good fodder for future podcasts. Hey, Evan, it was awesome chatting with you, man. You have a great week. Take care now.


References:

https://justinhealth.com/

https://www.evanbrand.com/

Recommended products:
Allerclear Histamine Support
Nasaline
Sinus Flush Bottle
Xlear packets
Xlear rescue spray
Navage Nasal Irrigation
NeilMed Sinus Rinse Complete Kit
Xlear Sinus Rinse Kit
Austin Air Healthmate Plus
Air Doctor Air Purifier
Whole House Water Filter
Water Filtration Devices
Clearly Filtered

Audio Podcast:

https://justinhealth.libsyn.com/natural-strategies-to-help-relieve-and-support-your-allergies-podcast-313

 

Natural Solutions for Seasonal Allergies

By Dr. Justin Marchegiani

If you suffer from allergies, you’re not alone–seasonal allergies affect an estimated 40 million to 60 million people yearly. The good news is that it doesn’t have to be this way. There are several underlying factors that make a person more prone to having allergies, and several natural solutions to increase your resistance to these immune triggers.

What Causes Allergies?

All aspects of health are important pieces of the puzzle: air quality, diet, exercise, sleep, stress, etc. Whenever we burden our body with stress–whether it be eating a gluten-containing muffin, or having a fight with a loved one–it adds a drop into our stress bucket. Too many drops, and the bucket is going to overflow. When our immune system is overloaded, it will react to an otherwise harmless substance, like pollen, as if it were a dangerous foregin invader.

The risk of developing seasonal allergies is increased in individuals with a co-existing condition, like asthma, food allergies, pregnancy, and even stress and trauma. These conditions affect your immune system, contributing more drops to the stress bucket.

Allergies are an immune system disorder. The body overreacts to a harmless substance by producing antibodies to attack, causing common allergy symptoms.

Common Seasonal Allergy Symptoms:

  • Congestion
  • Post-nasal drip
  • Excess mucus 
  • Sneezing
  • Runny nose
  • Itchy, watery eyes
  • Scratchy throat
  • Decreased concentration and focus
  • Fatigue, problems sleeping
  • Mood swings, Irritability
  • Asthma
  • Skin issues like hives or eczema

In addition to the above pre-existing conditions, anything which weakens the immune system will contribute to the stress bucket, leading to allergies. Recent surgery, physical trauma, underlying illness, and lack of sleep included!

Click here to consult with a functional medicine doctor and start feeling better today!

What are other stressors on the immune system? A poor diet is a biggie. Gluten, sugar, alcohol, and processed foods all weaken the immune system, leaving you more susceptible to gut imbalance (which affects the immune system), sickness, and yes–seasonal allergies.

Natural Remedies for Seasonal Allergies

  • Treat your nostrils with a Neti Pot or Saline Spray– Sterile saline solution can flush out allergens and calm inflammation in the nasal passages.
  • Quercetin: Quercetin can significantly lower inflammation and modulate immune response. Research also shows quercetin stops the production and release of histamine!
  • Nettle: Nettle blocks histamine production and reduces inflammation. A natural antihistamine, nettle can be used as a tincture or tea to calm allergy symptoms.
  • Probiotics: Allergies are linked to immune health–and so is the gut. By balancing gut health, the immune system benefits and allergies subside. Try a quality probiotic and consume fermented foods to boost beneficial gut bacteria.
  • Local raw honey: In a study published in the International Archives of Allergy and Immunology, those who received honey had better allergy relief than those on allergy medication! The key here is local and raw. Local honey contains the pollen causing your allergies, and raw honey contains vitamins and enzymes. If you want to use it in your tea, allow the tea to cool before adding honey to prevent killing the beneficial compounds.
  • Sleep: Getting ample sleep is crucial for the body to repair itself. The immune system thrives when the body gets adequate rest. Aim for 8 hours per night. Sleeping n a pitch black room, slightly cool (aim for 65-68 degrees), with white noise can help foster a good sleeping environment.
  • Essential oils: Peppermint eucalyptus, lavender and peppermint essential oils can help clear the nasal passages. Diffuse them, or apply with a carrier oil to the chest to help ease breathing and open the lungs

Takeaway

By eating an anti-inflammatory diet, getting enough sleep, and implementing some of the remedies above, you can reduce your allergy symptoms significantly. Allergies are not a sentence–you have the power to take charge of your health.

If you’d like help managing your allergies, click here to consult with a functional medicine doctor and start feeling better today!

New Study Finds Hair Dye Connected to Cancer

By Dr. Justin Marchegiani

Last month a shocking study revealed that women who dye their hair have higher rates of cancer. If this is true, the implications affect an estimated 75% of women in the US who dye their hair. Let’s dive into the study results and take a closer look at the risks of dying your hair.

History of Hair Dye

Having dyed hair has become commonplace, but not too long ago it was a rarity! In 1950 only about 7% of women dyed their hair. Now, around 75% of women dye their hair.

Back in Ancient Rome, women dyed their hair blonde with pigeon dung and ashes! After rubbing it into the strands, they had to add urine to act as ammonia and strip the hair of color. This sounds gross, and we’ve come along way from using essentially sewage to color our hair. Unfortunately, the chemical cocktail used on our heads these days may be presented nicer, but a breakdown of the ingredients may still alarm you.

Study Results: Hair Dye Linked to Cancer

A new study in the International Journal of Cancer reports a link between use of hair products, including dye and straightening treatments, and cancer.

The researchers also uncovered the following data:

  • Using permanent hair dye is associated with a 45% higher risk of breast cancer in black women and a 7% higher risk in white women.
  • The more frequent you use hair dye and hair straighteners, the higher the risk of cancer.
  • Women of color have an even more significant risk.
  • Black women using permanent dye every five to eight weeks had a 60% increase of breast cancer risk, while white women show an 8% risk increase.
  • Straightener products also correlate with a higher breast cancer risk, which increases the more frequently the straightener products are used.
  • Using hair straighteners every 5-8 weeks leads to a 30% increase in risk of developing breast cancer.

If you want to learn how you can decrease your risk for cancer, click here to work with a functional medicine doctor!

Beyond Dye: Straightening Treatments and Styling Products

Dye isn’t the only hair product to be aware of: most styling products contain dangerous chemicals, toxic fragrances, and other endocrine-disruptors. The average woman uses 12 personal care products a day containing 168 different chemicals, many of which lack sufficient safety data. Chemicals in mainstream hair products are linked to hormone disruptions, allergies, birth defects, organ damage, and even cancer.

“Fragrance” is a secret ingredient that seems to be lurking in everything these days, including hair dye, conditioning treatments, detangler, hair spray, and shampoo. This deceptive marketing term is a catch-all term used on ingredient lists to indicate a ‘trade secret’ recipe that can contain hundreds of synthetic chemicals–none of which has to be disclosed or even safety tested. What about the chemicals that have been tested? Many cause reproductive harm, respiratory issues, and some are known neurotoxins and carcinogens.

For example, phthalates are a key components in plastics. Dimethyl phthalate is a common ingredient in hair spray, though its presence is often not noted on labels. According to the EPA, known effects of short-term exposure via inhalation are irritation of the eyes, nose, and throat. Meanwhile, “no information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of dimethyl phthalate in humans.  Animal studies have reported slight effects on growth and on the kidney from chronic oral exposure to the chemical.”

One would hope for more of a proven safety track record of dimethyl phthalate as an ingredient in products that are used on a habitual basis, multiple times per week over the course of many years. Unfortunately, that is not always the case when it comes to personal care products.

Beautiful Hair, Naturally

If you are ready to embrace your natural hair and are looking for ways to support its health, growth, and shine, there are supplements and topical treatments you can safely use for more luscious locks!

  • A Vitamin B complex can strengthen hair, helping it grow longer without breaking.
  • Collagen promotes the growth of not only hair. One of the best sources of collagen is in bone broth. I recommend Kettle & Fire bone broth. If you’d prefer a source of high-quality grass fed collagen that you can add to your coffee or tea, click here to see which ones I recommend.
  • Omega-3s from wild-caught fish, antioxidant-rich green tea, and foods rich in vitamins A and C such as bell peppers, broccoli, and sweet potato all support health hair growth.
  • Try a coconut oil hair mask 2x/week for added moisture and to prevent split ends. To stimulate hair growth and healthy follicles, rub coconut oil into your scalp and roots.
  • Rosemary oil can stimulate hair growth, and is being used as a natural alternative to conventional hair loss medication!

It’s important to be aware of the risk associated with using products such as hair dye and relaxers. While dye alone may not be the sole cause of breast cancer for every individual, by knowing the potential risk, you can make informed decisions regarding the products you choose to buy and have exposure to.

Ready to take your health to the next level? Click here to work with a functional medicine doctor!

References:

https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32738

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1740925/

https://www.national-toxic-encephalopathy-foundation.org/fragsmoke.pdf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093181/

https://www.ncbi.nlm.nih.gov/pubmed/28683407

https://www.ewg.org/research/teen-girls-body-burden-hormone-altering-cosmetics-chemicals/cosmetics-chemicals-concern

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253722/

https://www.ncbi.nlm.nih.gov/pubmed/9577937

https://www.ncbi.nlm.nih.gov/pubmed/20183522

https://www.ncbi.nlm.nih.gov/pubmed/16283906

https://www.epa.gov/sites/production/files/2016-09/documents/dimethyl-phthalate.pdf

Fragrance: The New Secondhand Smoke

Fragrance: The New Secondhand Smoke

By Dr. Justin Marchegiani

Have you ever walked into a bath and body store, full of scented bath bombs and candles, and left with a headache, sore throat, or itchy nose? Those of us who are more sensitive may have already connected the dots between artificial fragrances and feeling foggy. While scented products are generally used with the positive intention of changing the scent of a person or a room, many people don’t realize the consequences. For the more sensitive among us, reactions can be immediate, but we are all at risk for the long-term effects of toxic fragrances.

What is “Fragrance”? 

“Fragrance” (or “parfum”) is listed as an ingredient in practically everything these days: body wash, shampoo, soap, perfume, laundry detergent, fabric softener, hairspray, dish soap, household cleaning products… the list goes on and on. While any of these may list the ambiguous “fragrance” as an ingredient, they all have very different scents. Which leads us to the question: what exactly does “fragrance” mean?

Seeing the word fragrance or parfum on an ingredient list indicates a “trade secret” recipe that can be composed of hundreds of synthetic chemicals, selected from a database of 5,000 various components. Not only are companies not required to disclose which chemicals they use,  none of these thousands of chemicals has to be tested for safety. There are some that have been studied, and the health effects are seriously scary. Reproductive harm, respiratory issues, and some of these fragrance chemicals are known neurotoxins.

Fragrance: The New Secondhand Smoke

Fragrance has been linked to:

  • Endocrine disruption
  • Hormone imbalance
  • Brain fog
  • Memory and concentration issues
  • ADHD
  • Headaches and migraines
  • Allergies
  • Respiratory problems
  • Birth defects
  • Damaged sperm

One example we can look at are phthalates, which help chemicals absorb into the body (alarm bells are already ringing). What are the associated risks? Reproductive system birth defects, hormonal changes, reduced sperm motility and concentration, increased damage to sperm DNA, obesity and insulin resistance, Type 2 diabetes, thyroid irregularities, asthma, and skin allergies, miscarriage, and infertility, to name a few.

 Click here to learn how to take your health to the next level!

EWG product testing found phthalates in nearly 75% of name-brand products, while not a single product listed phthalates as ingredients. This is because phthalates fall under the umbrella of a secret ingredient, and can be slipped into the chemical cocktail that results in one simple word, fragrance, on the ingredients list.

Second-Hand Fragrance

Think about the potential health effects linked to using phthalates that we listed above. This is just one of 5,000 ingredients that are mixed together to create a product’s fragrance. None of these chemicals are required to be tested for safety, yet we are exposed to them every single day! 

Some of us are more sensitive than others and have an immediate reaction to scented products, and will avoid purchasing them. However, the majority of the population (unwittingly) still uses these toxic products. Perfume, scented laundry, hair products, air fresheners… Just like cigarette smoke, these fragrances create an aura of fragrance that pollutes the air. At their core, second-hand smoke and today’s fragrance epidemic are both battles over indoor air quality. 

Fragrance: The New Secondhand Smoke

What Can We Do?

Shop with your dollars, and purchase products that are fragrance-free or contain truly natural ingredients, like pure essential oils. In fact, essential oils can take the place of a variety of scented products. doTERRA On Guard Cleanser is made of pure essential oils, including cinnamon, clove, eucalyptus, and wild orange. A lavender essential oil can be mixed with a carrier oil (coconut, avocado, olive, rosehip, etc.) to create a natural moisturizer. Shopping for fragrance-free products is not hard, but making them yourself adds an extra layer of fun & personalization!

Still have questions about fragrances? Click here to talk to a professional!

References:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1740925/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093181/

https://www.national-toxic-encephalopathy-foundation.org/fragsmoke.pdf

https://www.ewg.org/research/teen-girls-body-burden-hormone-altering-cosmetics-chemicals/cosmetics-chemicals-concern

https://www.ncbi.nlm.nih.gov/pubmed/28683407

Reversing Autoimmune Disease

Reversing Autoimmune Disease

By Dr. Justin Marchegiani

When your immune system response can’t distinguish between your body and any toxins you’ve ingested, the result is called ‘systemic inflammation:’ when your body attacks its own tissues. Your body might intend to fight off an infection or an allergen, but instead points the attack at your joints or your thyroid, or maybe even your whole body. This is how autoimmune conditions, such as arthritis, celiac disease, thyroid disorders, and lupus, begin to grow.

Causes of Autoimmune Disease

Causes of Autoimmune Disease

Autoimmune diseases typically stem from one of the following causes:

Genetic Predisposition: While your genes alone do not condone you to a fate of autoimmunity, having a family history is a good indicator that you should be proactive in preventing an autoimmune disease from developing.

The pathogenesis of autoimmune disease is multifactorial, meaning, just because you may have inherited the genes for an autoimmune disease, it does not necessarily mean you will develop one. Studies have shown that some combination of genetic and environmental factors are what ultimately cause or prevent autoimmunity from developing. In this article, we are going to break down some of the ways to prevent this from happening.

Leaky Gut: Food allergies, toxins in our food and environment, stress, gut dysbiosis and an inflammatory diet are causes of leaky gut. Leaky gut occurs when the gut lining is compromised, allowing large food particles and toxins to leak into the bloodstream, causing inflammation and autoimmunity.

Autoimmune conditions affect at least 50 million Americans, as well as millions more worldwide. However, autoimmune disease seems to exist almost exclusively in first-world countries. This is possibly linked to the diversity of the microbiome: in developed countries, we are regularly exposed to antibiotics and consume genetically modified foods laden with pesticides. These contribute to reducing the diversity of our microbiomes. Those in less developed countries have a wider range of gut flora, and don’t suffer from the same autoimmune diseases.

Click here if you are suffering from brain fog, digestive issues, or insomnia!

Trauma: Overwhelming stress or trauma, whether it be physical or emotional, such as a difficult break up, the death of a loved one, or a car accident, is enough to send your body into overdrive and trigger autoimmunity. The immune response due to physical stress (injury) causes profound inflammation, which is known to trigger autoimmune disease.

Up to 80% of people note that they experienced uncommon emotional stress before the onset of their autoimmune disease. Stress-related hormones are presumed to cause immune dysregulation, resulting in autoimmune disease. Stress can be responsible for more than just the onset of autoimmunity, it also feeds continues a vicious cycle of feeding the condition.

Prevention and Reversal of Autoimmunity

Prevention and Reversal of Autoimmunity

  • Eliminate any foods causing allergies or sensitivities. Here is a breakdown of what an elimination diet entails. Basically, by eliminating foods that are potential allergens, you’ll learn what your body feels like when you aren’t ingesting inflammatory foods. Then, you add back foods gradually and are able to pinpoint which foods are triggers for your autoimmunity or other issues you may have been experiencing.
  • Heal your gut to reduce inflammation. Your gut houses 70% of your immune system. If you don’t have a healthy gut balance, your immune system will be severely affected, contributing to autoimmune disease. An elimination diet can help you learn which foods are serving you and which are hurting your gut.
  • High quality probiotic supplements, eating and drinking probiotics in the forms of kombucha and sauerkraut, and drinking bone broth will all support a healthy gut!
  • Proper vitamin D levels. Research shows a strong correlation between vitamin D deficiency and autoimmune disease, cancer, and other serious diseases. This article studies the link between vitamin D and autoimmune disease in depth. Getting time in the sun, as well as supplementing with quality vitamin D, are ways to reverse and reduce risk of developing autoimmunity.

Click here for a personalized wellness plan!

  • Glutathione, the “master antioxidant,” helps your body detox any toxins you ingest. Glutathione is also a major player in immune system regulation, meaning it plays an important role in autoimmunity.
  • Zinc is essential for white blood cell production, and provides powerful immune system support (maybe you’ve heard zinc recommended to get over a cold quickly). In fact, studies have shown that those with a zinc deficiency are more susceptible to developing diseases.
  • Get good sleep will lower inflammation, heal your body, and reduce cravings for carbs, sugar, processed foods, and other junk that contributes to autoimmunity.
  • Magnesium A deficiency in magnesium increases production of proinflammatory cytokines, raising your body’s total level of inflammation, a trigger for autoimmunity. Magnesium deficiency is rampant in our society due to chronic stress, soil depletion, and high-sugar diets, so it is important to supplement with magnesium.
  • B vitamins support your immune system, hormones, sleep patterns, and much more. Vitamin B12 plays a role in your body’s production of white blood cells, which are essential components of your immune system. With lowered white blood cells, you are much more susceptible to illness, including autoimmunity.
  • Reduce stress Studies show stress can act as both a trigger and a modulator in autoimmunity, and stress-reducing techniques (yoga, meditation, massage) are viable treatment options.
  • Activated charcoal can be taken if you have consumed a food you are sensitive to, or any less than ideal foods. Activated charcoal binds to toxins to protect your body from inflammation.

If you are dealing an autoimmune disease, or have suspicions, please schedule a consultation with a qualified functional medicine doctor to assess your needs and help you heal.

Click here to talk to a functional medicine doctor about autoimmunity!

References:

https://www.aarda.org/news-information/statistics/

http://cshperspectives.cshlp.org/content/4/3/a007260.full

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899145/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036413/

https://www.ncbi.nlm.nih.gov/pubmed/21094920

https://www.ncbi.nlm.nih.gov/pubmed/18190880

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061980/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783422/

https://www.ncbi.nlm.nih.gov/pubmed/17364504

https://www.ncbi.nlm.nih.gov/pubmed/19276300

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746355/

Immune System, Tapping Technique and GI infections – Podcast Live with Dr. J and Evan | Podcast #131

Dr. Justin Marchegiani and Evan Brand engage in a lively and informative discussion about their recent clinical successes with their patients using the functional medicine approach. Listen to them as they dig into the root cause of their patients’ issues and turn chronic and seemingly complicated problems into success stories.

Know about the tapping technique which involves turning something negative into a better, positive thought. Learn more about GI infections, the bacteria or parasite that may be involved, as well as the tests and treatment options that are proven successful in the functional medicine world. 

 In this episode, we cover:

 03:50   Immune System, bacteria, and infection relationship

 15:50   Tapping Technique

 19:17   Treating Hypochloridia

 24:10   GI infections

 28:34   Enzyme Tests
 
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youtuve

 

 

Dr. Justin Marchegiani: We are live on YouTube here. Podcast live on demand. Also, live here on Facebook. Evan, how are you doing, man?

And again, Facebook people you gotta click on the link here uhm—I’ll put in the comments to see Evan’s pretty face and go back and forth on this. How we doing, man?

Evan Brand: What’s going on? I’m feeling really good today. We’ve got a blue skies, the trees are blooming which they probably—

Dr. Justin Marchegiani: Awesome.

Evan Brand: a year ago in Austin. So I’m enjoying myself.

Dr. Justin Marchegiani: Very good. So we got podcast on demand. So anyone wants to write in some suggestions as we chit chat here, we’ll figure out what exactly we want to talk about moving forward.

Evan Brand: Yeah. And I might as well post a link over here to my Twitter page and see if uh—people are paying attention over there. That way, if they’ve got questions, they can get them answered here.

Dr. Justin Marchegiani: Love it. Totally makes sense. Same thing, anyone on Facebook, too, every  chimes in first we can get this thing moving. But let’s uh—just talk about some clinical successes in the last week with patients. Any updates from you, man?

Evan Brand: Yes. So interesting update is uh—there’s a female client that comes to mind and she had seven, I believe, I have to go back at here stool test and count. But I believe it was seven infections and this is a combination of two parasites which—let me just pull it up, that way, I’m not just shooting into the dark here, but—Uhm— with these infections, we started a gut protocol and symptom improvement was seen. She was having a lot of irritable bowel symptoms uhm— running to the bathroom. So she showed up with H. pylori, Blastocystis Hominis, Entamoeba and Fragilis and Proteas  and Citrobacter. Somehow, cal protectin level was still low  which is intestinal inflammation where—

Dr. Justin Marchegiani: Yeah.

Evan Brand: –I look at but I was surprised. And so anyhow, we put her on this protocol. And this is like 8 weeks.  And the H. pylori while it’s still positive, instead of two viral factors, now she’s got one viral factor. The level of H.Pylori has dropped. The Citrobacter is completely gone. The Proteus completely gone. The Blasto is completely gone. But we still got Entamoeba. So there’s still the parasite and there is still the H. pylori there. So we’ve got work to do but yet, we’ve seen 3 or 4 things disappearing. So I think what the takeaway message is from me is that the bodies gonna heal in an interesting way. It may not heal everything at the same time. Some things may be easier to kill. Some things may disappear first, but you gotta heal yourself especially your gut, your microbiome. You gotta heal these things in layers. And that’s what we’re seeing here.

Dr. Justin Marchegiani: Yeah. So typically with a lot of patients that have chronic issues is there are some underlying stress, right? Emotional, physical, chemical stress but even deeper above and beyond that, there is some level – there’s some level of  infection that’s deeper that creating inflammation even though it didn’t show via calprotectin or it’s just creating leaky gut. And the whole leaky gut mechanism is getting the immune system fired up. The more the immune system is fired up, it’s just an energy suck for  your body. It’s like uhm—let’s say guests in you guest bathroom that you never go into your house. And they just leave the water on. Just a little bit—little drip, drip, drip. And then you get your water bill at the end of the month, and you’re like, “Where the heck did that bill come from?” And you’re like, “Oh, yeah. The faucet’s on.” But it’s like that with your energy resources. When got these bugs, it really—when the immune system is overactive. And even just a leaky gut, right? The more your immune system is overactive, the more it’s gonna suck your energy dry. That’s why when you get sick, the first symptom you get when you get sick is what? You get a lot of fatigue and malaise coz the immune system is sucking resources. Go ahead—

Evan Brand: I wanna hear uh—a recent case from you, but first I wanna ask you the question that I get asked all the time. And the answer really doesn’t matter because we need to fix the root cause no matter what. But people often ask well– chicken or egg? Was it that ma—my immune system got taxed first? And then I picked up these bacterial pathogens or these parasites? Or did I pick up the parasite and the bacterial pathogens and then that that set my immune system? What’s your take? Can it go either way?

Dr. Justin Marchegiani: Yeah. So typically it’s one of two scenarios, right? Typically someone gets exposed to a very high amount of infectious debris, right? Parasitic—parasites. So you drink some really bad water, you to go Mexico, you have really bad meal or at a foreign country, you get the Bali belly, so to speak. And then you’re overwhelmed with all of that infectious debris and then there’s so much of it that it compromises your immune system, you get diarrhea, you have a lot of gut inflammation that creates malabsorption. That malabsorption puts stress on all of your glandular systems and then you spiral downhill. That’s scenario number one. So just the infectious—the infection was so overwhelming, it just threw everything else downhill. Scenario number two is there some type of immune compromisation  that’s happening. Meaning adrenal stress, poor diet, poor sleep, or poor diet and lifestyle habits, low nutrient density. The immune system’s kinda a little bit weaker underneath the surface then you get exposed to some of these infectious debris at smaller micro levels that are in the food. And eventually makes its way to the system and creates inflammation.

Evan Brand: So yeah—so let me—let me clarify there. If we’ve—If we’ve got diet, lifestyle mostly dialed in, but let’s say people are cheating with gluten, for example. They still got intestinal permeability going on. You can still have good class, good sleep, blah, blah, blah. But if you’ve got just a simple thing like leaky gut, for example, you could potentially be more susceptible to pick up these infections regardless of whatever else is dialed in.

Dr. Justin Marchegiani: Yeah. I mean—here’s the deal with leaky gut, too. If you’re creating leaky gut, and then there’s some research, you know, on the non-celiac, gluten sensitivity side of the fence, that looks at these foods. Even if you’re not like reacting to a it, like symptomatically, and even if you’re not like having like IBS -like symptoms,  bloating, you know, gas constipation, diarrhea, that gluten can still create leaky gut. Where the undigested food particles in the gut can make their way into the bloodstream and create stress. And then the LPS that comes in there along with that, that’s the— the bacterial debris can get into bloodstream and create a lot of mood issues as well. So you can still have leaky gut and not risk from gluten— and still not respond to gluten in general.

Evan Brand: Yup. Yup. I just posted a post on uh—Facebook which I think might be a slightly controversial which was I wrote this little bit of a letter and I put kind of like these five things that have happened over the last year or so where people have said, “Evan, I’ve ditched psychiatrist or I’ve ditched my psychologist or my marriage counselor, or my conventional doctor because of functional medicine.” I kinda wrote the reasons why of how if you lower inflammation, you may need less adjustments at the chiropractor, for example. If you heal the gut, you start producing your neurotransmitters optimally, you might not you’re your antidepressants anymore, so you might not need your psychiatrist. Or if you heal your adrenals, you’re not gonna snap at your children anymore, so therefore you’re not gonna need the marriage counselor that is telling you need to stop yelling at your kids. And how basically how functional medicine can literally, not intentionally, but it’s just a side effect is that we can replace these other industries. I’m not saying these other industries are bad for mental health care or anything like that. But a lot of times, this is not root cause medicine. And my wife and I went out you with a friend of ours yesterday and she said she had a lot of stress, she had to put her dog down and she called up her psychiatrist and said, “Hey I need help, I’m freaking out.” What does he do? He prescribed her 60 Xanax and says, “Here’s your Xanax bars and take these.” And I told her, I said, “Listen, your anxiety and your stress from this issue is not a Xanax deficiency.

Dr. Justin Marchegiani: Totally.

Evan Brand: How about we do some emotional freedom technique. We start tapping. How about we cleanup the diet? And then before we left, out the parking lot, I had her do the quick coherence technique, the Heartmath, like the heart focus breathing.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And focusing on someone that she loved and we got done with it, and she said, “That was weird.”  I said, “What happened?” And she said, “I got tingly and warm.” I said, “Oh, it worked.” And she said, “What happened?” I said, “Well, you just took yourself out of fight or flight that you’re probably stocked in which is causing you to be dependent on Xanax and now we’ve pushed you into that parasympathetic rest and digest mode.” And she feels better. And this is what this is all about. Uh—a little bit of uh—off-subject uh—, but I just wanted to mention to people, check on my Facebook post and you’ll read about what I’m saying. I’m not saying these other uh— practitioners out there are garbage. What I am saying is that if you’re not getting a practitioner to focus on root cause, even if they are psychiatrist, if they’re not a root cause psychiatrist, then what the hell are they doing?

Dr. Justin Marchegiani: It’s all about resources, right? And in functional medicine world, we’re trying to help enhance your resources. So just like someone with more money in their bank account can buy more things, well if we enhance our mental, emotional bank account via healthy and diet and lifestyle functional medicine principles, we have more resources to deal with stress in our life. Whether it’s family, friends, being a parent, being present for our partner, just being able to do the hobbies of a hobbit—hobbits—uh—

Evan Brand: Haha

Dr. Justin Marchegiani: The hobbies and the habits that we have going on in our life.  I got uh—I guess I’m missing my uh – Lord of the Rings movies there. Yeah. So—It ‘s all about resources, right? So we have to make sure that we have enough resources in our system so we can allocate them toward these stressors. And I always tell my patients, “Have you ever tried dealing with stress on 0 night sleep? or “Try doing your taxes the next day when you’re getting like three hours of sleep?”  You’re just  not gonna be able to handle it. You don’t have the resources. So everything we’re trying to do is let’s test the resources of our body systems, let’s look where the hormone’s at, let’s look at where the gut resources are at, let’s look at detox and nutrient resources are at, let’s support them and let’s work on fixing them.

Evan Brand: Well, the analogy I like to use is we’re just using a big spotlight. Because a lot of different industries and health care, what they do is they use like a little laser pointer or like one of those tiny little keychain flashlight. And they shine something real dimly into one corner. And you’re like, “Oh, Justin looks like we found something. We found some anxiety issues, here’s the Xanax.” But instead, we come in with a giant spotlight and we’re like, “Whoa, look at the left corner of this microbiome. We got parasitic and bacterial infections, which can steal your nutrients, can mess up your blood sugar and cause anxiety. Look over here,  we’ve got some adrenal issues. You got spiking of cortisol that’s gonna need to be addressed.” And then we shine the spotlight over here, “Oh, take a look at our detox pathways on the organic acids, you’ve got trouble over here.” And “Oopp, we shine the spotlight behind us, here’s mitochondrial issues. This is why you’re so fatigued.” And that’s the—I think that’s the greatest analogy. It’s a little laser pointer or a little small keychain flashlight, which is just pinpointing one industry of psychiatry or psychology or whatever versus exploring everything. Which is why for you and I, it’s tough for us to become the blank guy. You know people out there, “the thyroid guy” “ the detox chick” “ the bone broth chick” You know what I mean? It’s really gonna be tough for you and I to just say we’re the blank person because I don’t want to limit myself. I wanna let everyone know it is all encompassing.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And if rest and niche yourself down, I think it’s a bad thing.

Dr. Justin Marchegiani: Yeah. Like from a marketing standpoint, right? Marketing is just telling the truth attractively. You know it’s good to have the niche because you wanna reach the people that have special conditions. Because if like, my specialty is thyroid. Number one, I have—I have or had a thyroid issue. It’s under control. Autoimmune thyroid issue. So I’m more passionate about that issue. But again, to treat  a thyroid issue, you have to be able to treat all of the systems. So it’s kind of a mythology, like you don’t just ever treat thyroid, you treat the whole thing. But you may mark and put information out there that’s gonna resonate and speak to someone with a thyroid issue more. But again, the underlying issue is from education and clinical standpoint. We’re addressing the key underlying surface issues and the deep root issues as well. So we’re never ignoring it. We may speak to someone uhm—more specifically and get into the more nuances of that condition, but it all comes back down to the foundational stuff that we always talk about.

Evan Brand: Right. I would say my specialties would be— it’s become parasites really. I mean, I’m seeing so many each week and it’s just so fun. I guess because I had parasites.

Dr. Justin Marchegiani: You had a parasite, you.

Evan Brand: Uh—Yeah. And also depression, I mean because depression is what got me into this whole thing. IBS and depression in college, I mean, like I told you before, I had to figure out when I went  into a college class, where’s the bathroom. Coz I have to get out in the middle of the class to run to the bathroom.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And so for me, depression, IBS, parasites, you know, those are all linked together—the whole gut-brain connection. And I really am empathetic for people that have struggled with that because it’s so common and if you diagnosed with IBS, that’s a pretty generic diagnosis. And unless you’re with functional medicine practitioners, you’re gonna get an acid blocker, an antispasmodic—

 Dr. Justin Marchegiani: Yeah. Absolutely.  

Evan Brand: — or some other drug and—

Dr. Justin Marchegiani: Well actually, you were diagnosed with IBS, right?

Evan Brand: I was.

Dr. Justin Marchegiani: And you use the antispasmodic, you used the medications that helps with the gastroparesis. You know—

Evan Brand: Well, they never –

Dr. Justin Marchegiani: They even do that—

Evan Brand: Well they never got to use it. They try. They wrote me the prescription pad but I denied all three of the drugs.

Dr. Justin Marchegiani: And the thing is, too, we can also use natural medicines for a lot of those things. That may not fix the root cause, right? There’s root cause medicine and there is using natural medicine in a way that’s gonna help alleviate the symptoms that’s gonna up regulate physiology so things work better. But we have to still be investigating and digging to the root cause, right? So we’re dealing with someone with gastroparesis or low motility, we may add in things like ginger. We may add in things like carnitine. We may add, you know, higher amounts of mag citrate to keep that uhm—migrating motor complex moving. But we are still digging in deep. We’re still making the diet, the lifestyle. We’re still enhancing digestive nutrients, uh—hydrochloric acid enzymes. And then we’re digging deep for the infections. And we’re trying to lock in those diet and lifestyle habits, right? The supplements are great because they can give us that symptomatic relief while we continue to dig over here to the root cause. So as long as you have, you know, that  four pace envision that addresses some of the symptoms without the side effects, you know of some of the drugs, which may have more side effects than what you’re treating, and then working on the functional medicine plan, I think we’re in a really good place. 

Evan Brand: I agree. Yeah. I actually got a good—good success with that IB Synergy product from designs which get Bonigut in there. It’s got the 5-HTP. I had a guy with just super bad IBS and I said, “Man” I mean he was critically, critically stricken with both diarrhea and constipation just alternating every other day.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So I have him going with that 5-HTP Bonigut blend. And he got better. Now we start to wait for lab results but yeah—I mean  sometimes we will do some of the quick fix of band-aid situations to fix things, but we still got to work backwards. I guess to answer these questions uh—should we answer the question about the cancer question here or shall we just make a whole show on the future?

Dr. Justin Marchegiani: Yeah. We’ll do a whole show on that. I’ll get some experts on. I got Dr. David Jocker is coming next month as well. He was in the truth about cancer series. And we’ll go on ketogenic diets and we’ll talk more about therapeutic ways to address cancer outside of just the natural chemotherapy. So we’ll hold that one that—we need more time for that.

Evan Brand: Yeah. Agreed. Uh—Samuel asked, “What is the tapping technique? Can you show us? Well since most of our audiences are gonna be audio listeners we’re not gonna take up the air time to show you the technique, but the best resources—EFT (Evan-Frank-Tom) EFT.mercola.com and you can just view the different acupressure meridians that you’re gonna tap. But then also, you’re gonna learn about the affirmations that you can use for emotional freedom technique and that’s something Justin and I use all the time.

Dr. Justin Marchegiani: I think it’s helpful. I’m—I’m gonna just give it 15 seconds of airtime here, so—just—I do two hands coz it’s adding it’s more efficient. But you just tap the  inners part of the eyebrow, the outer parts of the eyebrow, under the eyes, I do under the nose, and the bottom part of the chin the same time. And then I do both collarbones. So I do this, and you can go top of the head and tap midline. So I do two hands coz I just feel like you get more stimulation. So I go here, and I’m just thinking about whatever is pissing me off, my wife, I just think about it.

Evan Brand: Haha

Dr. Justin Marchegiani: I kinda give it a number. So if I’m a t like 6/10 regarding irritation, I just think about it. Whatever that issue is, whether it’s like, you know, the person driving  in front of me is so slow  or whatever. And I try to knock that 6 out of 10 so that 10 is the worst.  6 is like 60% to being at the worst. I try to knock it down to a4 to a 3. And so every round—every 2 rounds or so, you kinda just check back in and see if you knock it down. And you go as you kinda knock everything down to a 3.

Evan Brand: Yeah. And we have—I—I start at the top of the crown which I usually like—many ways—

Dr. Justin Marchegiani: You can do that. You can start there, you can end there.

Evan Brand: Now do you do the sides? I know Mercola, he’s big on the side of rib cage under the armpit.

Dr. Justin Marchegiani: Yeah. I do that, too, sometimes. It’s just wasn’t good for a video.

Evan Brand: Yeah. So you criss cross?

Dr. Justin Marchegiani: Yeah. I do two at the same time just coz it’s stimulation.

Evan Brand: No. I mean you criss cross your arms so the underarm’s like this. I do like a monkey.

Dr. Justin Marchegiani: Haha

Evan Brand: And then—and then finish with the wrist. I typically finished by tapping the insides of the wrist together then doing the affirmations. So even though I’m angry, or even though I’m anxious, I deeply love and accept myself. But you gotta say the affirmation verbally. I tell people if you can, if you’re just embarrassed, then don’t do it. But why be embarrassed? Nobody—nobody is paying that much attention to you.

Dr. Justin Marchegiani: Yeah. That depends, too. Like you can do this stuff, and you can kinda say like if you’re at—let’s say, if you’re lying in bed and you’re just really stewing on something and your wife’s next to you and you don’t wanna wake her up, then you can just kinda think it in your head. And then you can just, you know, do the affirmations, tap like this.  And then you can tap here, and think about the issues.

I like them to end, though, with a positive thing. So you can end with something positive. So then I just go into like, “What is it that I want to manifest?” So I’m going into right there. I’m thinking about whatever I’m gonna try to create or produce in my life, I just tap it while I’m thinking about it. And the whole idea of tapping is you’re just stimulating various meridian systems that have been mapped out via acupuncture system for thousands of years. And really what it’s doing is it’s neutralizing the negative response that’s stored in the limbic system or in that subconscious of your—more in the psychological side of it. And you’re trying to kinda rewire it so you can get a good pattern there instead. So then, naturally that reflux is to go back to the better thing and not to the negative thing.

Evan Brand: So if you do affirmation about the bad part, would you do like an affirmation about the bad part and an affirmation for a positive?

Dr. Justin Marchegiani: Yes. So I start off with the negative and just try to lessen—lessen it first.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Coz if you’re—feeling negative, it’s really hard to be positive when you’re negative so I try to decrease the negative to about a three. And then I go into the positive because then, you are in a better place to deal with the positive, right? It’s kinda like when someone tells you to relax and you’re pissed off, like relax, calm down. You just wanna punch him, right? Like, “No, I’m too wound up, come on.”

So I wanna get that dialed in and then now I’m relaxed, now I can rewire it and create some positive things.

Evan Brand: I like it. I like it.

Dr. Justin Marchegiani: So calm down first, and then work on manifestation.

Evan Brand: Should we answer a couple of more questions here?

Dr. Justin Marchegiani: Yeah. Let’s hit it, man. Let’s hit it.

Evan Brand: Solam asked, “How long does it take to heal hypochloridia?”

Dr. Justin Marchegiani: It totally depends, right? If you have emotional stressors that are unresolved ore you’re eating foods that are incredibly inflammatory, maybe never. But if you’re making the root causal changes and your managing your stress, and you’re fixing the underlying gut stuff, I would say within 3 to 6 months, you have a really good chance of not needing hydrochloric acid to digest your food. But again, everyone is different. A longer—the longer the issues been going on, the more severe the infections, and the more infections that are layered in there, I’d say longer, up to a year, at least.

Evan Brand: Yeah. I’ll just have my two cents to that, too. If you had a previous history of a prescription, as a blocker’s proton pump inher—inhibitors are now it’s open to counter like the Xanax or the Toms, or anything like that, or—

Dr. Justin Marchegiani: Yup.

Evan Brand: Or if you’ve had H. pylori which we’ve chatted about many times, then I would say it may lengthen that time, too, to fix that stomach acid issue.

Dr. Justin Marchegiani: The longer that gut’s has been worn down, the more the immune system is revved up like you get patients are just supersensitive to every little thing. Like I can’t even put in an enzyme, I can’t even put in our apple cider vinegar or lemon juice or the smallest fermented food sets them off. It’s really hard and you’re looking at a couple of years to really dive into it because the immune system is so revved up and it’s so ready to attack the smallest invader that it’s so hard to put things into help and heal it because it’s looking at everything as a foe not a friend.

Evan Brand: Right. We really, really have the baby step in those cases so that’s why—

Dr. Justin Marchegiani: Totally. Yeah. I mean, just like you heal, with you know, food is medicine there, you go really slow and you do lots of things in broth form, in soup form so it’s – so it is so palatable. There is very little digestion that has to happen. And typically one supplement at a time and one nutrient at a time, titrate up from low to high. Even if it’s something that they can handle, if they go high dose, off the bat,   their immune system just freaks out.

Evan Brand: Well I wanna hit on something you just mentioned which is if we’re talking 1 to 2 years, it takes extreme patient—extreme patience for patients and clinicians because for us, that is a very intensive case for us to take on.

Dr. Justin Marchegiani: Totally.

Evan Brand: And you know, maybe this is to toot our own horns, maybe it’s just calling out the obvious that we do take the time, you know, with people we’re working  with. Sometimes it maybe 30-45 even an hour-long call for a follow-up just to take these baby steps. Whereas, let’s jus say some of the clinicians that we’ve seen out there, it’s too cookie-cutter approach and they don’t have the mental bandwidth or capacity for empathy to baby step this people.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So it’s here’s your cookie-cutter protocol, good luck.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Where with us, we’ve really, really, really gonna get super details.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And so this is why if you go and you buy like a leaky gut online program or some other type of program, and you get limited results and you get to us, we’re not gonna be surprised if you suffered through that, and you didn’t get a good result. Because at the end of the day, that’s why  Justin and I haven’t created  online courses at this point because it’s—it’s hard for us to sleep at night thinking that we’ve created a program that’s too cookie-cutter. We’ve really got to figure out a way that we’re gonna be able to work in all the minutiae and the small details and the variations—variation A, B and C, D for different people.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So if someone uh—packages something up all beautiful and says, “Oh, it’s $297 and all your problems are gonna be healed.” Uh—please be a little bit skeptical  of that.

Dr. Justin Marchegiani: I agree. And I’ve talked to you about a patient that I had today that email in that was dropping out of care. And we try to always set realistic expectations. This person just had her labs reviewed a month or two ago, and had multiple parasitic infections, severe adrenal dysfunction, HPA axis dysfunction, and then a lot of issues on her organic tests. Uh— detoxification issues, mitochondrial issues, and we just started with simple adrenal support, made diet and lifestyle changes and she had some— some side-effects so we try to cut things down, go slower. And we’re gonna kinda reconvene and work on supporting detoxification, but person had dropped out. Now, the problem is, to have expectations that things will work off the bat when so many things are wrong like that, expectations are incorrect. So  a lot of people they have preconceived notions even if you spell it out to them and you let them know, “Here’s where we’re at now, here’s where we’re going.” They forget because they—they want it done now. And they think because things didn’t work in that initial uhm—in that initial experience, that there is no way to fix it. So continuing to harp on patients in managing their expectations, even though they have a lot of stuff they’re projecting from past failures, we kinda have to get through it. Make sure expectations are real and that make sure they know, “Hey, here’s where we’re going now. Here’s where we’re going next.” These things ahead that may have to be dealt with for us to really see great changes.

Evan Brand: Yup. Well said. We got another question here.

Dr. Justin Marchegiani: Let’s hit ‘em.

Evan Brand: Let’s hit Steve’s question. After all GI infections are eradicated, how long does it take the gut to fully heal? All my infections are gone, but I’m still dealing with IBS, leaky gut and issues after H. pylori.” I’m gonna hit on this first Dr. Justin Marchegiani, if you don’t mind.

Dr. Justin Marchegiani: Yup. I know you’re gonna say it, by the way.

Evan Brand: Okay. So – haha if—

Dr. Justin Marchegiani: If you say it—If you say it, I’ll—I’ll tell you that.

Evan Brand: Okay. Alright. Please. Alright. So here’s what I’m gonna say. You say all your infections are gone, but you’re still dealing with IBS, leaky gut, and issues, I would like to know what test was this that says all your infections are gone because I bet all of your infections are not gone.

Dr. Justin Marchegiani: Yes! Whoo! I knew it. Yeah. You’re totally right.

Evan Brand: Haha

Dr. Justin Marchegiani: Yeah. You’re totally right. And then also, just making sure that you have the digestive nutrients on board to help heal the gut lining and the digestive support to break down the food and then I would make the food more—more palatable right now. I’d be looking more at the GAPS or an SCD or more of a soup or broth approach that makes the food really easy to take in. No raw veggies, uhm—try to keep it really palatable so the body can access it without much stress.

Evan Brand: Alright. So the beauty of the Internet, Stevie says—Stevie replied and he says, “DRG” Well, uhm— Justin–

Dr. Justin Marchegiani: It’s missing a lot of them. It’s missing a lot. You gotta do the DRG with the GI map. I a—I never do the DRG by itself for the most part—always both. You gotta do both.

Evan Brand: Yup.

Dr. Justin Marchegiani: And if there’s still an issue with the DRG and the GI MAP, I want them go for the  41 side-by-side.

Evan Brand: Yup. Agreed. So, Stevie, not that—you know, we’re not diagnosing you. That’s not what these calls are for. But, hey, Justin and I have seen a lot of false negatives with DRG and some other test out there. So potentially some stuff going on. And I would like to add a couple of points about like the—the issues, the leaky gut type stuff. You know, make sure you are doing some of the easy supports, too. You know, chamomile is great. You can do chamomile in a supplemental form. You’ve got chamomile teas, uhm—you’ve got L- glutamine. So there are some leaky gut supplements that why your til—still trying to figure stuff out, you can still be taking support of nutrients in the meantime while waiting for retest.

Dr. Justin Marchegiani: Absolutely. Totally. Let’s hit  the uh—last question there by—E Center Riley. See here, just diagnosed with Hashimoto’s, TPO and TGB bodies, 465 is that high? Eliminated the foods, gluten, dairy, soy, balance in blood sugar, hard with 5 kids. What should I focus on next? So 465 is definitely high. The LabCorp reference range for TPO is 34. Anything 34 above is considered positive—I think it’s above 34. 34 below is considered positive. And anything about 20, for me, I considered to be subclinical. So that is high. Anything above or around 500 is definitely high. I’ve seen patients at 2000, though. I’ve seen patients that go from 2000 to below a 100. Now, my goal is to get people—If I were you, I’d like to see a 70 to 80% reduction in that. Again, maybe you were higher before you made those changes. So I’m not sure if it was  gluten, dairy, soy. That stuff was cut out and then you saw the drop. But either way, uhm—getting enough selenium in there, 400 micrograms of selenium, addressing the underlying infections, things like H. pylori, Blasto and Yersinia can be coming to increase the antibodies. And then making sure the adrenals are looked at. There’s a strong adrenal-thyroid connection and a lot of people who have thyroid issues also have adrenal issues. And remember, TPO is a microsomal or essentially it’s uh—intracellular microsomal antibody that helps bind the thyroid hormone together. So if you’re making antibodies to that, it’s gonna prevent that thyroid hormone that I—Iodination process from occurring. So making sure we have the adrenal support there because the adrenals help produce cortisol. Cortisol is an anti-inflammatory that’s gonna help with the inflammation. And with the TPO there uhm—you could potentially have increase in hydrogen peroxide, especially if there’s small amounts of iodine getting in there. So get them the selenium will help neutralize that hydrogen peroxide into H20. High quality H20 which is uh—not gonna be as inflammatory.

Evan Brand: Well said. Yeah. And so uhm—Isabella Wentz, I just did podcast with her a couple of weeks ago. Actually that was my last uploaded episode. And uhm—we’re talking about bacterial infections, too. So you mentioned some of the parasites and she’s seen the same thing the parasite but also the bacteria. The Klebsiella, the Citrobacter, and all these autoimmune triggers has been bad guys for uh—these Hashimoto’s situations and these antibodies, so—

Dr. Justin Marchegiani: Yeah.

Dr. Justin Marchegiani: So, look for the bacteria, too, and you can definitely fix this stuff and you can make significant progress.

Dr. Justin Marchegiani: Absolutely. I mean one person here, wildlab access, “How do you test for various enzymes?”Number one, if you have gut stress, you probably have low hydrochloric acid. And if you have low hydrochloric acid, you probably have low enzymes. Why? Because hydrochloric acid is important for acts of—for converting pepsinogen to pepsin which is the proteolytic enzyme. Hydrochloric acid lowers the acidity of the chyme, which is the mixed up food in the intestine. That inten—that food that chyme that goes into the small intestine which the acidity then triggers the pancreas to make bicarbonate, it also triggers CCK that then caused that the gallbladder to produce bile that also stimulates the pancreas to make light based trypsin and chymotrypsin and all the enzymes that come down. So if you have enzyme issues, you also have hydrochloric acid issues, but we can also assess it by looking at enzyme markers, like elastase, too, which will uhm—look at that in the DRG or the GI MAP test.

Evan Brand: You better get that frog out.

Dr. Justin Marchegiani: Frog out. It just attacked me, man. I’m like, Ugh—

Evan Brand: Alright.

Dr. Justin Marchegiani: My water—so uh—yeah. Elastase, I think it’s elastase 1 is the enzyme marker we typically look at for uhm— low enzymes. But typically, just assuming that we have digestive stress, let’s assume it for sure.

Evan Brand: Yeah. I mean that’s the same—the same answer that I would say for the leaky gut. I had people say, “Oh, can you test me for leaky gut?”  It’s like, “Yeah. We can go to Cyrex and spend 500 bucks if you want to, but based on your symptoms, I guarantee there’s intestinal permeability. You’ve got XYZ. And we can—we don’t need to spend the 500 bucks on that test. Save your money for the organic acids, your comprehensive stool panels, the GPL-TOX, maybe heavy metal testing. Save your money for that stuff that you can’t really guess on.

Dr. Justin Marchegiani: Yeah. Absolutely. I agree, man. Well, anything else you wanna hit off the bat here? I mean I think—I had some really good successes last week, too, with some patients that had chronic pain, chronic mood, chronic energy, hair loss. And I mean—just really simple things. We—we fix their hormones, this person has autoimmune thyroid, uhm—hypothyroid as well. T3 was super low, it was uh– T4 to T3 conversion issue, dysregulated cortisol. They had a lot of malabsorption and they had a couple of infections and we just—we just took them down the map. An then just everything first time around, uhm—just knocked in place. I mean it’s like you swing the bat once and it’s connected. It’s gone. Those were the patients where its like, “It’s just so rewarding coz it’s just—it’s easy” And then you have  some patients where it’s a lot more trial and error and digging in. So it’s nice to have those home runs every now and then.

Evan Brand: Oh, man. I—so I had a home run earlier with this guy that I got off the phone with name Dion. And he was on an inhaler. An asthma inhaler.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And also I believe he was taking uh—allergy medication, like a prescription allergy medication.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Maybe it was one or the other. He alternated or he was on the inhaler something. But he was on prescriptions for allergies. And all we did is we cleaned up the diet, we’ve addressed some gut infections. He had candida and I believe a couple bacterial infections. I don’t believe he had parasites. I have to look back. But I remember a couple of infections, fix the gut, uh—supported adrenal’s basic adrenal support, some adaptogens. And I talked with him today and he said, “Evan, I’ve not used my medication in the last six weeks. And everything is blooming here right now. All the trees and plants and everything are blooming and normally, I’m debilitated. He said, “I’m completely fine.”

Dr. Justin Marchegiani: Isn’t that awesome?

Evan Brand: How in the world just by working on the gut and adrenals am I not allergic to the environment anymore? It’s just like, “Oh, it makes me feel so good.”

Dr. Justin Marchegiani: I see that all the time, too. And hydrochloric acid is one of those things that’s really great with allergies, too. You notice that?

Evan Brand: Ain’t that weird? I mean since digestive enzymes, I told him, I said, “Man, we’ve gotta keep up digestive enzymes.” And then actually I am gonna send him a bottle of some of the like natural herbal anti-histamines, just in case. Because he started sneezing on the phone. I’m like, “Whoa, maybe you’re not all the way out of the water yet. Have this on hand, in case you need it.” So the coresatin in, the rutin, some of those–

Dr. Justin Marchegiani: Hesperetin

Evan Brand: Yeah.

Dr. Justin Marchegiani: The things I love for allergies: number one, just really get a good air filter. I used one by Advanced Air. You can see that at justinhealth.com/shop Look at the approved products. I like it. It’s good. Uhm—and then your natural anti-histamine degranulating compounds. In my product, Aller Clear. Stinging Nettle, coresatin, and then you’re gonna have like some vitamin C in that, some potassium bicarb as well. So those are really good. And you can go up to eat. The nice thing about it, just not gonna be drowsy. So you can get that allergy support without getting the drowsiness and then really make sure the diet is anti-inflammatory. Up the hydrochloric acid because HDL is really important with low—with allergy. It’s gonna make a big difference.

Evan Brand: Yup, Yup.

Dr. Justin Marchegiani: Ginger. Ginger is phenomenal, too, for allergies. Really good.

Evan Brand: I love ginger. So it’s a great nutrient. I’d do teas, ginger kombucha, there’s so much you can do with ginger.

Dr. Justin Marchegiani: Oh, yeah. By the way, right after this, I’ve got a new grill. So I’m gonna go out, I’m gonna grill some grass-fed hotdogs, right? And then I’ve got some sauerkraut with mustard. And I’ve got a nice ginger kombucha, I’m gonna open up. So I’m really excited for my lunch break today.

Evan Brand: Nice. What kind of grill? Is that one of those  pellet jobs?

Dr. Justin Marchegiani: I actually—I got a new Webber just because it’s—it’s—my other one was 10 years old. And then the knobs are starting to go. So I got a nice, little Webber Spirit. So it’s great. It’s got three burners. Love it. And uhm—I got a smoker that I use sometimes for ribs on the weekend just like a 4-hour job. So it’s good to have a day or an afternoon to kinda be at home to enjoy that one but—Yeah. So love my grilling. Try not to get things charred. Try to keep the heterocyclic amines and the polyaromatic hydrocarbons to a minimum.

Evan Brand: Agreed. Agreed, man. Cool. Well I don’t have one on my end.

Dr. Justin Marchegiani: You wanna have a share?

Evan Brand: No.

Dr. Justin Marchegiani: Hope you guys are liking these calls here. We wanna do more. We wanna connect with the listeners. Our purpose really is to serve and help people get their health back. If people want more feedback, or want more kinda like rolling up the sleeves and specifically diving into your case, go to notjustpaleo.com or justinhealth.com, click on the schedule buttons. And we are here to help you out. Evan, anything else, man?

Evan Brand: That’s it. Have a great day people, drink clean water, get rest, reduce stress, be grateful. It’s gonna go a long way.

Dr. Justin Marchegiani: And people on Facebook, I’m hoping we can get Evan on here soon. We gotta just  figure that out. So hopefully, soon we’ll do that. So Evan, great chatting with you, man. We’ll talk soon.

Evan Brand: Take Care. Bye.

Dr. Justin Marchegiani: Bye.

 


References:

https://justinhealth.com/products/aller-clear/

https://justinhealth.com/products/advanced-pure-air/

http://catalog.designsforhealth.com/IB-Synergy-60

EFT.mercola.com

notjustpale.com

http://notjustpaleo.com/227-dr-izabella-wentz-hashimotos-protocol/

Allergies and Your Immune System

Allergies and Your Immune System

By Dr. Justin Marchegiani

Spring is here and so are allergies! This is the time of year were allergies are in great abundance. Flowers are in bloom so our grasses and many other types of pollen that our immune system has not been exposed to the last six months or so. When our body is being exposed to these environmental compounds, it is responding to them as if they are a foreign invader, like a bacteria or a virus. We know this is an inappropriate immune response; these environmental compounds are not out to hurt us. Our immune system is being overly sensitive; we need our immune systems to calm down so it can be more intelligent and pick out the real immune threats from the benign ones.

There are certain things we can do to help make our immune system more intelligent. Eating an anti-inflammatory diet is very helpful, this helps take stress off the immune system, it helps lower cortisol, it helps our immune system stay strong and smart so it can pick out the bad invaders from the not so bad. When we are overtired it’s common for us to overreact during certain situations. This analogy holds true for our immune system, the more inflamed we are, the increased chance our immune system will overreact.

Medication and allergies

 Medication and Allergies

 

The majority of medications that help with allergies such as Zyrtec, Allegra, Singulair and Benadryl usually work one of two ways; they suppress the immune response and or weaken the immune system or decrease the histamine response. If you are the kind of person that is interested in having optimal health the two pharmaceutical alternatives mentioned above don’t sound too great. It’s much better to make the immune system smarter and more intelligent and not just weaker and docile. Anytime you weaken the immune system you make yourself more susceptible to other chronic degenerative diseases.

Click here to find out how you can improve your immune system.

Some of the above drugs have side effects involving weight gain. Many patients I know are trying to lose weight, and are more than likely not aware that some of the medications they are using maybe potentially antagonizing their weight loss and body composition goals.

allergies

Some of my favorite natural compounds to help address allergies and inflammation

 Compounds of allergies

Quercetin: Is a bioflavonoid and it’s very helpful in helping in balance out the immune system, quercetin helps decrease inflammation as well as decrease your body’s histamine response. Histamine is what makes your body stuffy, congested, and makes your nose runny. This provides a natural solution for people that may have use Benadryl or other types of algae-based medications. Quercetin also has no side effects and is a powerful antioxidant as well.

NAC (n-acetyl cysteine): NAC is a sulfur-based amino acid that is a precursor for glutathione. Glutathione is our body’s master antioxidant and is primarily used to help quelch the fire of inflammation and free radical stress. The more stressed we are the more our antioxidant and glutathione systems are taxed and the increased chance our glutathione reserves will be depleted.

Many people out there aren’t eating enough high-quality protein sources and cruciferous vegetables such as broccoli, asparagus and cauliflower. If we don’t have the raw material amino acids to help make glutathione we have an increased risk of being overly inflamed and being susceptible to allergy symptoms as well.

Fish oil is an essential fatty acid in the omega 3 family which increases the prostaglandin 3 pathway (it’s highlighted in the picture below).  This pathway is anti-inflammatory and helps put out the fire in our body.  Avoiding refined omega 6 fats like vegetable oils like canola, soy, and cotton seed oil to name only a few can help decrease our prostaglandin 2 pathways which make us more inflamed.  As inflammation increases so does our chance of allergies.  Eating foods that help put out the fire and avoiding foods that help increase the fire is an easy way to help improve your allergies.

Consuming 4-8 grams of high quality fish oil that is in a triglyceride form tends to be the best.  Make sure you are consuming a high quality brand.  If your are burping up the fish oil, the brand may not be of good quality or your body isn’t producing enough enzymes to break down the fat.  A fish oil with lipase included can help decrease this problem.  To get to the root cause of your allergies, click here!

 

EPA-Fish-OIl_eicosanoid-pathway

 


The entire contents of this website are based upon the opinions of Dr. Justin Marchegiani unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Justin and his community. Dr. Justin encourages you to make your own health care decisions based upon your research and in partnership with a qualified healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Dr. Marchegiani’s products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products.