Natural Strategies to Help Relieve and Support Your Allergies | Podcast #313

Some people with allergies may find relief by using natural plant extracts and foods that will act as antihistamines. So in this video, Dr. J and Evan Brand talk about allergies and natural and functional medicine approach. 

Dr. J and Evan recommended initial things that can help you manage stress. Stress hormones wreak havoc in the body, especially in the immune system, making seasonal allergies even worse. Consider stress management methods such as meditation, taking time out for self-care, and avoiding over-committing your schedule. Constant house cleaning can get rid of many allergens and help relieve your symptoms. 

Often, allergies will get worse by toxins within our body. The liver is a great negotiator of inflammation in the body, and when it is working overtime metabolizing our stress, alcohol, medications, and processed foods, allergies can flare up. Detox your body by eliminating fried foods, sugar, alcohol, and other toxins from your diet. For more detailed steps and solutions, don’t miss out on the full podcast to fix or avoid allergies!

Dr. Justin Marchegiani

Dr. Justin Marchegiani

In this episode, we cover:

0:36       Conventional Approach on Allergies

7:49       Getting the Diet Dialed In

12:54     Gut Infections Connecting to Allergies

16:08     Air Purifiers

20:30     Natural Supplements

30:29     Low Histamines

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Dr. Justin Marchegiani: Hey guys, it’s Dr. Justin Marchegiani here with Evan Brand. Today we’re going to be talking about natural solutions to help relieve and support your allergy springtime is officially here. It’s like the last week everything around my home has been blooming, it’s been amazing. Love that feeling of that transition from winter to spring. So that’s really exciting. But with that comes a whole host of other challenges with allergies and sinus issues and headaches and, and runny nose and itchy eyes. And we’re going to talk about natural solutions that we implement with our patients clinically in real life that actually get results, not just you know, stuff you read in the blog post, but real stuff. Evan, how are you doing, man?

Evan Brand: I’m doing pretty good. Why don’t we talk about the conventional approach first, I think it’s good when we do that comparison and that contrast for people. So you go down the street, you see the Joe Blow allergy clinic, you’ll walk in, they give you some type of medication and you go home. And that’s pretty much as far as it goes in regards to treating allergies. And you know, they have different options. I know some people get shots. I know some people do nasal spray, some people do anti histamines orally. So there are several options. But they all have the same goal, which is really just a band aid. It’s trying to block receptor sites maybe decrease inflammation somehow from a drug perspective, but it’s not addressing the root cause of the allergies in the first place. And I’m not going to speak for you but my opinion is that allergies are a side effect. Humans have been outside for forever. And now all of a sudden, we can’t tolerate the outdoors and we need drugs to manage us to handle the outdoors. That’s not natural. That’s not primal. That’s not ancestral. I don’t think that there is an ancestral allergy. I think this is a new problem based on the toxicity of the planet, but also other issues that we’ll get into in regards to the internal health of the human host.

Dr. Justin Marchegiani: 100%. So, if we talk about some of the mechanisms of how these medications work, I think that’s helpful. Right? So there’s a bunch of ones that are out there. So you have things like Allegra, right or Claritin, I think they work the same way. They’re kind of like an h1 receptor. They’re they’re like an anti histamine and they weren’t they antagonize the h1 receptor. So there can anti histamine, right? I think Pepcid AC also works, I think on the h2. So you have anti histamine ones, whether they’re Allegra or Claritin, they tend to be more on the anti histamine side. Zyrtec similar as well. They’re a h1 blocker. They’re they blocked the h1 receptor as well. And so you have a lot of the anti histamines the problem with those is they come with a lot of side effects like drowsiness, right, drowsiness, brain fog, cognitive, low energy, so not good. If you have to perform, you have to function you have young kids, right? Most people have to be on it, you know, at 100% to be functioning in the daily life. So that doesn’t really work too well. And then you have more advanced things like I want to say Singulair would be one that would be more anti histamine based, there’s, I’m sorry, more steroid based, more corticosteroid based. So there’s ones that are more steroid based, or people that have, you know, more significant allergy, whether it’s throat closing or needing an inhaler, of course, then you have things like albuterol, that may get worse, right. And so these are, you know, the steroids tend to get used when there’s more advanced allergies. And then of course, you have some of the allergy shots, which tend to be a little bit more natural, which tend to be exposing yourself a little bit to the allergen as a way of kind of building up an immune response, that’s not going to be over responsive com that allergy season, those are some of the big things off the bat. And I think you want to highlight Evan?

Evan Brand: Well. I want to highlight the fact that billions and billions of dollars are being spent per year globally with people being on these medications. And it really gives them a false sense of security, meaning, yeah, it might help the symptoms. But this is not getting to why someone is unhealthy in the first place. And I could go down a whole rabbit hole with this. But I mean, just because you get a shot for something, and now you feel a little bit safer. Well, you didn’t under you didn’t address the underlying issue with your histamine intolerance in the first place. Is there a gut issue going on? Is there some sort of imbalance with your gut bacteria, you have a lot of histamine producing bacteria, are you eating a lot of food allergens and your bucket is already so full of allergens, the now the outdoor flower blooming puts you over the edge See, if everything else in your quote bucket is not filled, you should be able to tolerate the outdoor environment just fine. And so I think we should mention mast cell issues. mast cell activation could be triggered by mold. It could be triggered by Lyme it could be triggered by co infections like bartonella babesia. And you’re definitely going to have a lot more issues. Now. I’m not somebody that would say I have outdoor allergies, but I have felt a little different with everything blooming. And I’m just doing my herbal anti histamines to help which we’ll get into but I know that there was an underlying trigger, because for my whole life 30 plus years I haven’t had allergies. And now I feel a little weird a little spacey when everything’s gloomy. So now I’m like, oh, okay, my buckets full from these other things. So all I’m saying is, I just want people to really focus on the whole picture. have their whole health. And if you have allergies, that’s just the warning light or the check engine light on your dashboard, but there’s probably something else under the hood going on that you should address because there might be other issues that are downstream that you don’t even realize are related like allergies and diarrhea, allergies and constipation allergies and insomnia, allergies and anxiety and panic attacks and heart palpitations and blood pressure issues and skin issues. I mean, we could go on and on about how allergies is just one piece of this whole puzzle.

Dr. Justin Marchegiani: Yep 100% and then just to kind of recap here I made a mistake here Singulair is not a corticosteroid essentially is blocking luco triangles, which are kind of going to be an immune response from the leukocytes. So some of the allergy medications that are going to be on the steroids side that’s gonna be like Nasacort, Nasanax, Flonase will be another Rhinocort, [inaudible], those are going to be more of the steroid options which are going to be more severe. Then you have the leuco trying blockers right which is the Montelukast sodium, which essentially is the Singulair and then you have the h1 receptor site blockers or antagonist. And those are going to be like your anti histamines, right? That’s gonna be like your Allegra, your Claritin, right, your Zyrtac, those are going to be more on the anti histamine side. And some make you drowsy, Allegra may not as much. But in the end, like you mentioned, Evan, these medications are not getting to the root cause, especially if you weren’t born out of the womb with allergies. This is not something that’s something that’s developed over time typically, because your antigen bucket or your stress bucket has been filling up over time. And diet plays a big role. The more inflamed your body is, the more inflamed your body is, the more your immune system will over respond to allergens in the environment. It’s kind of like the more inflamed your back or your joints are. Something very simple like going for a walk may inflame your near back. But we know a walk generally speaking shouldn’t be in flaming your near back, right? So it’s not a proportional response. Same thing with allergies, it’s not a proportional response, your body shouldn’t be responding to allergies, like it’s a virus or some bacteria in the environment it shouldn’t be. And so the first thing we have to look at is what are the big stressors in your stress bucket out of the gate. So the first thing we look at is diet. One, the solution to pollution is dilution. Are you drinking nice, good clean filtered water with extra minerals in it? Are you eating kind of an anti inflammatory diet, a good paleo template, we’re keeping grains and refined sugars out. And especially if you have allergens, dairy and grains are big ones. And you may have to cut out nuts, seeds and eggs as well is a good one out of the gates where you’re focusing on healthy meats, healthy vegetables, dialing in the carbs, according to you, and then also having healthy fats that are going to be away from the process vegetable fats as well as gonna be a good thing out of the gates. 

Evan Brand: Yeah, and we’ve seen people have significant improvement just by getting the diet dialed in. I mean, I’ve heard 50 60% improvement with allergies just by eating clean, people that were eating gluten for breakfast and dairy for lunch on their salads, you know, doing the ranch dressing and their bread crumbs and all that crap and then we get him eating clean and all of a sudden the allergies are better and people that are either reducing their medication or they’re able to completely get off their medication, which is a big goal. For a lot of people they feel dependent and they feel scared like well what if I travel or what if I go somewhere and I don’t have access to this medication? You know, they feel the same way they do about their eyeglasses. What if I break my glasses when I’m on a desert island and I can’t see people feel that way about allergy medication they feel very afraid to to try to live without it because they know how they’ll respond. The good news is it’s possible that you don’t need it if you can fix all these other issues.

Dr. Justin Marchegiani: And histamine is basically an immune response due to these allergens, right allergens are just foreign antigen, they’re their foreign proteins or compounds in the environment, whether it’s dander in Austin cedars really, really big this time of year, you can see like literally you go on the parking lot to coats the cars, you know this, this yellow cedar. So the first thing is, make sure all the diet and lifestyle things are dialed in. The next big thing, especially if you’re outside a lot during the days, is most people’s sinuses are full of these allergens and dander and pollens and so a good sign is flush protocols and the bee Bay. So during allergy season, morning and night is going to be essential. If it’s really acute, you may do morning, midday and night but morning and night, you want to be able to go to bed with a clean sinus and you want to wake up with a clean sinus. You may even want to do it when you’re at work as well or when you come home from work especially if you’re inside for the day like around six, seven o’clock, maybe do it then so you can get some relief. And of course we’re doing a really good sailing or a high quality filtered water or a distilled water solution. We’re going to be adding in some sodium bicarb and some minerals. So it’s pH balance so won’t irritate the sinus mucosa. If you just do a whole bunch of water up there and it’s not balanced, it could really create irritation. So make sure it’s balanced with minerals. Now we’ll typically do some things that have Xylitol in there, which is very good at breaking up bacterial biofilms and also have some antifungal qualities. So that’s wonderful. I’ll do two to three seconds of flow down each nose blowing in between. That’s wonderful. I’ll even chase it a before with a spray called Xlear rescue spray. It’s wonderful because it has about six different herbs in there, parsley and pati arco and all of oregano, and they’re gently diluted in the pH balance water with some saline. And so I chased that up because as an antimicrobial anti biofilm effect, and then I flush it out each sinus and you can do like a good sinus irrigation bottle is Sinusgator, there’s, there’s the Nasaline, there’s the Neomed bottle, the Xlear bottles, you just type in sinus irrigation or sinus irrigation bottle on Amazon, I’ll put the ones that I like below. If you go to my site, I have a recommended list of all the things that I use, Evan does as well. And so take a look at those and we’ll kind of have recommendations below in the link so you guys can see it. But the first thing is get the sinuses flushed out get the crap out of the sinuses, if it’s sitting there for six or eight or 10 or 12 hours, it’s gonna create inflammation. So the first thing is flush it out. And if it’s really sticky, or like has a hard time flushing, you know, use some of those biofilms to break it down. That’s kind of my first recommendation out of the gates there. And in preventing these things from brewing.

Evan Brand: Yeah, that’s great. And the rescue is intense. So if you’re, if you’re like super inflamed, take it easy. I love it, though, it feels amazing. And then also, we like silver too. So we will use some professional, we’ll use some professional professional version of silver, we call it Argenton. And that one works great. So I like to do both, I’ll do a little bit of the essential oils. And then if we think there’s like a more colonization issue with mold or something like that in the sinus, we’ll use the silver. And it can be very, very helpful. And I just want to make a note to people because I was one of those guys who said, Well, I don’t have any sinus problems, because I never had any runny nose. I never had like what I thought was a stuffy nose. Like I could breathe fine. But man, when I started doing some of the sinus treatment and these protocols, whoa, I realized I had like 30% more breathing capacity. I’m like, Whoa, I mean, I really opened all this stuff up. I didn’t know it was bad to begin with. So if you’re one of those skeptics like me, who’s like, Oh, I don’t have sinus problems, try it and see what happens. You may feel that you can breathe so much better.

Dr. Justin Marchegiani: Oh, yeah. And especially if you’re like you got young kids, because I you see it with young kids all the time. I have young kids, you’re their friends or whatever they’re hanging out with, they got runny noses, like non stop all the time. And I’m like, yeah, your kids probably got a little biofilm colony up there and need to work on flushing it out. Because the more that’s hanging up there. So anytime we see a kid, you know, our kids with chronic runny nose for a day or so we’re flushing that thing out within a day or two, we’re not going to write out and that works phenomenal. And then you can also use things like n acetylcysteine, to dry out those sinuses to which can be very helpful. So there’s a lot of mucus you can dry it out with the NAC, which is excellent. Very, very good out of the gates.

Evan Brand: Yep. So let’s talk about the guts. I want to hit on some of the gut infections. And we hear Justin’s cat if you hear me out. That’s his cat.

Dr. Justin Marchegiani: I just gave him a little kick under the table, like “get out of here!” 

Evan Brand: Maybe he wants some sinus rinsing. I know. So Oh, God would be terrible. No, no, that’d be impossible to do. Alright, so let’s let’s hit on the gut. So because this is this is a big deal. And I’ve had many, many, many, many people with histamine and sinus problems say that the single biggest thing they’ve ever done beyond the sinus rinsing and the actual coat allergy treatments was actually just fixing the gut. And I believe this is because of all the histamine producing bacteria that we see and all these bacterial overgrowth cases. So if you’re coming to work with us clinically, what we’re going to be doing is looking at your urine and looking at your stool to be looking for different infections or imbalances. And the good news is when you use herbs to rebalance all these bacteria, now you’ve drained the bucket so much that you can handle the outdoor environment. And so in fact, even some of the reviews on some of the products we use that people will say, hey, these herbs cured my histamine intolerance. And we did nothing with the sinuses, we did nothing in the quote, allergy realm, we simply fix the gut. So I don’t want people to ignore that. That’s why I was saying I was a little frustrated in the beginning because people will go to the allergy doctor and they never bring up the gut. They never bring up the diet. They just don’t even have a clue.

Dr. Justin Marchegiani: 110% So, so the first thing is, it’s like get the inflammation down in your gut. That’s going to be food. Excess refined sugar, inflammatory foods, junky omega six process fatty fats, which are going to be like soy, canola safflower, right if you’re going to do any plant based fats, coconut oil, olive oil, avocado oil are going to be better some palms gonna be great. animal fats are going to be of course awesome. And then if you can tolerate ghee or butter, great if you have allergies out of the gates pull those out because those can be mucus forming. I always say get your allergy straight in and make those one of the first fats you add back in and see how we do because if we can handle it, I want you to handle it. I want it in There. And the next thing after you have all the food stuff dialed in, and then you’re doing sinus irrigation. I like doing the rescue spray first because it is intense, like Kevin said, so then I put it up there and I chased it with some saline behind it, therefore it flushes it out, cleans out antihistamine, anti inflammatory anti histamine benefits. Because the problem with allergens up the nose if you’re outside, and then you come back inside to a nice clean home, even with awesome air filtration, which air filtration is a huge, important component to this. You’re still breathing all this dander and pollens up your nose all day long. That’s why you got to flush it. And that provides the relief from those allergens. And then of course, we want a really, really good air filtration. So Evan and I are big supporters of the Austin Air healthmate plus, which is good as a couple. They have an allergy machine too, but I think the healthmate Plus is the best out of all of them. Because of the charcoal, the zeolite. It’s a bigger filter last longer. And then it has the potassium iodide coating which filters out the volatile organic compounds, the voc’s which are going to get in mattresses and paints and new furnitures and that’s an extra allergen that could be adding to your histamine bucket as well.

Evan Brand: Oh yeah, speaking of air purifiers, I’ve got a cool update for you here. I’m going to see if I can load the email from one of the head honchos at Austin. Because I wanted to ask them about aluminum nanoparticles, you know, they’ve done some air sampling of what people call Kim Trails. Meteorologists say it’s conspiracy, and it’s a contrail. It’s just exhaust vapor. Don’t worry about it, even though Bill Gates plan just got shut down. They were gonna do the solar blocking, basically, anyhow. But this plane flew into these trails and tested and found that it has aluminum nanoparticles. So long story short, I asked our guy at Austin, and I said, Hey, hoping to find out if this air system can filter aluminum nanoparticles. And the guy who did analysis on the trails in the sky, he found that the aluminum was around 400 nanometers. And the guy said, Yes, four nanometers. 400 nanometers equals point four microns. And the Austin filters down 2.3 microns at 99.97%. So now Yes, our filters will handle this. No problem at all. So whether or not you believe the geoengineering thing is going on whether you simply want to filter, the allergens plus the stuff out in the sky, either way, you’re covered with the Austin and so contact our office if you want to get ahold of Dr. J, or myself, and we would love to help you. I’ve got one right here in my office, and it runs 24 seven. And I wish you could smell the air in here. Because it smells like nothing because it’s so pure.

Dr. Justin Marchegiani: I 100% agree. Like there’s a lot of controversial things that are out there. But here’s the deal. If we just talk about the things that we know, which we know, pesticides are out there, right? We know you have voc’s in your home from paints and that new couch robot and the new furniture. We know that there’s allergens out there. We know this potential smoke, especially if you’re in certain areas in California and the west coast where there’s fires throughout the year. We know those things are part of your stress bucket. And they’re they’re a part of that antigenic load. So you want to at least filter them out. And if we have other things, you know, aluminum salts, and Berry and other stuff going on there great. You’re also going to have benefits from that as well. So want to make sure that’s clear. The goal is to decrease all the stress bucket and you’re going to be inside sleeping eight hours a day, you’ll probably be inside at least 12 hours a day on average. And most people with the environment and the world that today we’re while people work from home. And so having super high quality air is incredibly important. super high quality water is very important. And then having very nutrient dense anti inflammatory, low toxin food is foundational. And then after that we can kind of talk about natural anti histamines and things to help kind of dry up sinuses. So I like NAC. I like propylene I like quercetin. I like stinging nettle. I also like things like potassium, potassium bicarb. I also like things like kidney glandular and D A O dia mean oxidase. My plug here is a product called Allerclear which has some of these things in it. I know Evan has a allergy product as well Evan, what’s yours called?

Evan Brand: Histamine Support.

Dr. Justin Marchegiani: We’ll put the links down below. So if you guys are enjoying the content and you want to support the show, feel free and purchase that from us. We appreciate it. We’re only recommending things that we recommend for our family and friends and patients. So those are helpful. Now again, I always draw a line like okay, what’s conventional medicine doing? Zyrtec? Allegra Singulair? Nasacort, right? We already know they’re like anti histamines h1 antagonist, steroids, right. luco trying blockers. That’s the mechanism over there on conventional medicine, which we know has more side effects right. Now, especially with the steroids, that’s a big one that can stress out your adrenals and create blood sugar issues and potentially can create issues with joint loss and bone loss.

Evan Brand: Let me add one thing before you ever get before you move on. So another mechanism that makes you actually worse and more dependent on those medications is that a lot of those conventional medications Actually down regulate or deplete your body’s do production. So now you’re even in more trouble. So you mentioned da o and you and I like to use that. And that helps with the ingested histamine. Meaning if you’re going to eat a high histamine food, we can give you supplemental do extract, and then that’ll help degrade the histamine coming from your diet. However, if you’re on those medications, you’ve now drained your do and you’re likely going to have more histamine intolerance, digging yourself even deeper in the hole. So I just wanted to add that in while you’re hitting on the comparing.

Dr. Justin Marchegiani: Yes, yeah, so we have conventional on this side. And then we have like all of these natural things, supplements that I just mentioned, quercetin bromelain do now these are better. These are much, much better, less side effects. Some of them are going to be our actual nutrient base like glutathionr building blocks, right, really helpful there. Potassium, super helpful. Kidney glandulars, da L, but a whole bunch other B vitamins and b, 12, and vitamin A. So those are actually really good. But I urge you, right? Don’t just listen to this and say well, I’m going to trade my Zyrtec for kidney or Dr. J’s Allerclear, try to actually make root underlying changes. If eating a whole bunch of grains and dairy and sugar, try to focus on the root cause stuff. Or if you know you’re outside a lot, and you’re not doing sinus irrigation, or you don’t have air filtration, try to get the external environment in your home, external environment in your sinuses and your internal with your body fix first, if you can. Now it’s okay if you go to the supplements at some point, but try not to go to them first, because then we’re just kind of acting like conventional medicine. Even though these have less side effects. Like Evan mentioned, they don’t deplete do some of them build it up. And some of them also have nutrients. So still better. But we don’t want to replace palliative care, which is supplements, we want to get to the root cause as well. It’s all about getting to the root cause.

Evan Brand: And it’s very simple. But I hope everyone is at least taking their shoes off when they enter their house. I mean, what a simple way to reduce bringing in oil and gas and pesticide herbicide who knows what else so you know, if you’re not already take your shoes off before you come in the house. And then if you have any carpet, so there, there are some carpet cleaning solutions that we use that are essential oil based, where if you had a pet, for example, that brings a lot of stuff in from outside, and that’s irritating you you can rent your carpets with this cleaner. And then also laundry solution, we do have some essential oil laundry solution that we use. And that will actually help to treat mold and pollen and all that on your clothing. So if you’re out like rolling in the grass, which is fine, you might want to just treat your clothes a little bit to make sure that they’re okay, but what let’s go back into the supplements because you were hitting on some good stuff. So also, in some of the products you and I use is vitamin C and vitamin C can actually help degrade the histamine. It’s amazing. My body.

Dr. Justin Marchegiani: Yeah, so essentially there is like anti histamine to granulators they help break the histamine down. Okay. And then there are essentially anti histamines they have natural, they decrease the production of histamine, right. And then we have the DA o enzyme support which does kind of also help degrade the histamine down as well, right because da o dia mean oxidase helps break the histamine down. Like Evan mentioned, a lot of the medications deplete the eo so they actually create long term dependency on it. It’s kind of like people that have proton pump inhibitors or acid blockers, well, it creates more problems because you’re not breaking down your proteins, your fats and your amino acids, therefore you have more issues down the road with other symptoms, right? Got to get to the root. And then Evan kind of alluded it one big other, let’s say, antigen, antigen or compound that goes into that stress bucket is if you’re if you’re washing your clothes, or your sheets, or your laundry with dryer sheets, or any fragrance laundry, no bueno. That’s a big, big thing. If you’re just conventional, at least get the like I like the all free and clear. That’s a good one that’s like dermatologist approved for like eczema and like chemical sensitivity that’s at all major stores. So you can always get the all free and clear. You can do seventh generation free and clear. There’s a couple of other brands that are out there that have just essential oil based no sense no nothing like that. That’s ideal. And ideally, no dryer sheets. And if you need more support to get extra odors out. There’s baking soda is a baking soda company makes one called wash soda wash soda, essentially baking soda for your laundry and it’s got ammonium or pseudo it’s got sodium bicarb in there and it just sucks out any mold or kind of like more pungent smells in your clothes. And so if you need that, that’s a great way to kind of get your clothes and your laundry clean without extra chemicals and crap in it.

Evan Brand: Candles. I mean hopefully I don’t have to beat the drum on this too hard. Hopefully you and you all listening have heard enough of us talking about this. But for anybody new. Please get the synthetic fragrances out of your house, you’re destroying your hormones. You know, man, you’re affecting testosterone and estrogen and women Same thing for you. So any Glade plugins, air fresheners after you poop, turn the exhaust fan on and use essential oils if you have a nasty smelling poops. You know you don’t need to be using synthetic toxic chemicals because that’s filling up your bucket. Then you’re using Pine Sol to clean your floor. So make sure your floor cleaners are legit. And those are clean. Make sure all of the cleaning chemicals you’re using are clean, seventh generation or branch basics. There’s so many good brands now there’s no excuse to not use clean products. When you’re cleaning your dishes, make sure you’re not using synthetic fragrances in your dishwasher. You can use free and clear for that, and your hand soap, your shampoo, your conditioner, your deodorant, everything needs to be cleaned, because you’re just filling up your bucket. If you’re exposing yourself to all that garbage. Now, you could do all that stuff and still feel bad. So that’s where we come in and do some of the functional testing to assess your gut. We’ll look at mitochondrial function, we’ll look at neurotransmitters amino acid metabolism, fat digestion, there’s so much that we look at from the testing perspective, we’re just giving you some good strategies today that can help but there still is a deeper layer that we need to investigate. And that’s where we come in.

Dr. Justin Marchegiani: 100% out of the gates. And so just to kind of highlight a couple of things there. You talked about the gut. That’s important. h pylori, fungal overgrowth. SIBO can create stress in the gut that creates more histamine. Imagine that histamine bucket filling up. So as you mentioned, gut issues create a lot of inflammation like a lot of these mast cell issues even like mast cell, Mass cell, right? mass cell activation disorder, right? Well, that’s just a sign that you’re inflamed and your immune system is spitting off histamine got to get to the root underlying issue. A lot of people talk about things like it’s the cause, but they’re really talking about the effect, right? Oh, my arthritis, my arthritis. Well, that just means you have an inflamed joint. What’s the cause of that, though? Of course, we know that’s the effect, right? inflammation in that area pain, right? We know that’s the effect, right? But what’s the cause? Right? So you have to always say most people in conventional medicine and even natural medicine, get people talking about the effects, but don’t address the cause. So make sure if you’re labeling anything, it’s only worth labeling something if you can connect it to a cause. If not, you’re just describing the symptoms that are presenting itself, which aren’t hard to do.

Evan Brand: Agreed. So yeah, if you were diagnosed with like a mast cell, or you suspected like masel activation m casts for short, you got to get to the big triggers. I talked about that in the beginning, mold, bartonella, Lyme, babesia, any kind of like tick borne issues, mosquito borne issues, vectors like that, they can aggravate your system and can cause you to be more allergic. So you may have to treat those things. I know, for me personally, you know, I know that just treating Lyme and co infections has made me feel better with some of my reactions. So you may need to dig a little bit deeper. And that’s really where you want somebody on your team because just trying to do this alone. It can be challenging, and you’re going to end up with a supplement graveyard and buy stuff you don’t need. So yeah, the herbal anti histamines are great, but what led you to need those in the first place? That’s, that’s the question need to ask. 

Dr. Justin Marchegiani: And I agree. And I can tell you like, there are some low hanging fruits that can do amazing things I’ll give you Case in point I had one patient, literally before me went to Mayo Clinic. She had chronic sinus issues. They’re literally telling her that, that that’s it like she asked she needs she’s already did surgeries didn’t relieve it. They’re telling her I think she can do just cut out cut out simple things like grains, her sinus issues were gone. And Mayo Clinic literally told her, there’s nothing she can do. She’s already on the surface, nothing else they can do all the medications, we just kind of grains gone. It’s like what it was that easy. Like, sometimes you have to kind of shake your your like, you kind of have to like, you know, give yourself a little wake up because you think oh, you’re gonna have to go into some elaborate protocol, and sometimes simple foundational things, move mountains, and you’re like, how did that happen? But that’s why we kind of have our checklist in our flowchart. And we don’t ever skip things no matter how elemental or easy. It seems like it would be it can move the needle sometimes.

Evan Brand: Yeah, now and I would just totally repeat that in a different story. You know, a lot of people, even practitioners like you and I, we could easily get lost in the weeds, we could go down these complex rabbit holes, and then we can lose sight of the foundations. And I see a lot of practitioners doing that part partially due to marketing, right, they have to become the thyroid guy, they got to become a guy. So so they’ll skip over foundations because it doesn’t fit into their brand, which is totally stupid. But my story is I had a female client a few weeks ago, and she just had extreme shortness of breath. And she didn’t know if it was like post COVID or what it was. But anyway, we looked at her ferritin on her bloodwork, and all the doctors had been like 20 doctors, her ferritin was seven. Oh my god, forget you. And I know. I mean, if you’re less than 20, you’re not going to be able to catch your breath. So we started to boost up her ferritin. But in the meantime, based on everything else during the initial call, I thought it could be like a histamine problem as well. So I said why don’t you just I’m going to give you this low histamine God, I want you to just eat low histamine until we get your labs back. When we did the lab review call. She said that it was 90% better. She said that within 48 hours of going low histamine. She was at least 50 to 60% better with her breathing. She could barely catch her breath while we were talking. She could speak in full sense It says without having to stop just just doing the lab review. I’m just pointing out, we didn’t even get to look at the data yet. Just a low histamine approach was enough to get her better. So this is in your allergist is not I’m sorry. I mean, if you’re an allergist out there and you’re prescribing low histamine diet, please email us, maybe we’ll do a podcast with you. But I don’t think this is happening. And there’s people sitting somewhere in an allergy room, an allergy office clinic right now. And they’re going to go home with the medication and they’re not going to learn a single thing about low histamine diet.

Dr. Justin Marchegiani: Exactly. And I agree, sometimes low histamine needs to be added on top of maybe our paleo or autoimmune thing, and I have a handful of patients right now where I had to go to that tool. And it can work amazing now that what are low histamine, paleo foods that are pretty common, any of your age meats, so like bacon, those kinds of things, pepperoni, salami, even if it’s pasture fed, or organic, your citrus fruits going to be a big one, sometimes your nuts and seeds. And I would say sometimes your fermented vegetables and your fermented drinks, even if you’re like, Hey, I’m, I want to get my probiotics and naturally, that sauerkraut or that kombucha may be a problem. Sometimes you have to go and pull that out. And so that’s, that’s a big thing we have to look at. And then also, sometimes mold in the environment could be a big thing. Now, I don’t go there first, because there’s too many other things that typically have to go there. So we’ll add that to our list. And especially if we have visible more for sure. But if people are feeling better coming back in their home, that’s usually a good sign. Most people with allergy season this time of year, it’s a punctuated response. And they really feel worse when they’re outside. That’s when you kind of know that it’s probably more environmental than not, if it’s just mold inside normally, it’s an all year round kind of thing. Would you agree on that, Evan? 

Evan Brand: Oh, yeah, I would agree. Yeah. And with like, our air purifiers and everything, I know that I feel significantly better when I’m in my house. Yes. So to me, I’m like, Okay, good. We I’m kind of the canary right. So I can pick up on things. And so I think if people are in tune enough, you should know, like, if you’re out at the store, and you’re outside, and then you go in your home, Do you get any relief? If not, then your home could be a contributing factor. And we can rule that in RL.

Dr. Justin Marchegiani: Exactly. And then of course, the good scientists irrigations wonderful, we’ll put links for that below. We talked about the diet, talked about food, we talked about supplementation, we’ll put links for everything. And then outside of that, hormones do play a valuable a very important role. So women with chronically low progesterone and people with low cortisol, in general, these are kind of natural anti inflammatory hormones. If they’re chronically lower depleted, they can affect your immune system. And so again, we know medications like nasal core, if you destiny, they’re steroids, right? And so they’re giving you steroids to kind of help with the inflammation of the allergens. And so we know if your natural steroids are incredibly lower depleted over time, for many reasons, we mentioned already, looking at your natural progesterone, your natural cortisol levels may play an important role. So taking a look at the adrenals taking a look at the female hormones, especially right around day 20 or in the luteal phase or so is very important. It plays a very important role.

Evan Brand: Good call. I mean, we could probably do a whole part two on that the adrenal allergy connection. Yeah, totally. I know. adaptogens helped me feel better. So I don’t even think we fully understand adaptogens and how they may help with stress response, but they may help with allergy response to I mean, there’s definitely a really cool, yeah, yoked up a whole new can of worms there. So I know. 

Dr. Justin Marchegiani: We’ll leave it at that we may want to do a follow up on this the hormone allergy connection that maybe we’ll save that for another week coming up?

Evan Brand: Well, I hope people enjoy this as much as you and I do. I mean, just listening back and trying to like, listen to our conversation. As an outsider. I’m like, wow, this is such amazing information. And you’re not hearing about this. So I really hope that you guys listening will share this with your friends, your family, and review us go on your Apple podcast app. That’s the best place to review us. And look at Dr. J show. Look at my show. And just click five stars. If you think we deserve it and give us some words, give us some words of affirmation. Tell us what you think. Because this really helps us. And we don’t have to do this. We just love doing it. And we love sharing with people. You know, we get hundreds and hundreds and hundreds of 1000s of people listening per year. We just love it. And if we can just put a dent in the world and make people feel better than our job is complete. So please, sharing is caring. And if you need help clinically, you can reach out to Dr. J he would love to help you with these issues. The website is If you’d like help for me, my website, has all the info. You can book free calls with our staff and talk to us about your symptoms, your goals, what’s going on, we’ll see if you’re a good fit for care and take it from there.

Dr. Justin Marchegiani: Absolutely. And we appreciate you guys for you know sharing everything and, and writing some good reviews and putting your comments down. It helps keep us inspired and it gives us more ideas of future topics to write about. So put your concerns on there. make notes and things you want to hear about as well love to see it. And that’ll give us good fodder for future podcasts. Hey, Evan, it was awesome chatting with you, man. You have a great week. Take care now.


Recommended products:
Allerclear Histamine Support
Sinus Flush Bottle
Xlear packets
Xlear rescue spray
Navage Nasal Irrigation
NeilMed Sinus Rinse Complete Kit
Xlear Sinus Rinse Kit
Austin Air Healthmate Plus
Air Doctor Air Purifier
Whole House Water Filter
Water Filtration Devices
Clearly Filtered

Audio Podcast:


Managing Environmental Allergies | Podcast #309

In this latest podcast, Dr. J and Evan are sharing their approach in managing patients who are dealing with environmental allergies. Dr. J and Evan have some recommendations for good digestive support, allergens,  home air filters, etc. to identify the root issue and address the problem! 

Environmental allergies can cause mild to severe symptoms, including sneezing, headaches, fatigue, and coughing. Preventing exposure to environmental allergens is the best way to treat them. You may not be able to avoid the allergens that trigger your symptoms. Your healthcare provider can help you create a plan for treating your allergies through home remedies and medications.

Dr. Justin Marchegiani

Dr. Justin Marchegiani

In this episode, we cover:

1:32        Environmentally Sensitive Patients

4:01       Checking Environmental Allergy Issues

8:35        Autoimmune Diet

14:46      Air Filters

17:44      VOCs (Volatile Organic Compound)

23:50     Gut Healing Nutrients

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Dr. Justin Marchegiani: And we are live it’s Dr. J here in the house with Evan brand. Today we’re going to be chatting about supporting and getting to the root cause of your environmental allergies. Evan, how are we doing today man? 

Evan Brand: Doing well, excited to dive into this because the leaves are falling at the time we’re talking. And so many people complain, I just got a new, different I guess a a better life insurance plan and the lady came over, you know, the examiner who comes and takes your blood work and stuff for your life insurance. And she comes in and she’s like, Oh, my God, my head is some old lady, my head, my eyes, my nose, my ears. I’m like, what’s going on? And she’s like these, these outdoor allergies. And she was just completely miserable. And she’s on all the conventional meds. And I talked with her and asked her, you know, would you eat for breakfast? pastries, you know, so it’s just interesting that conventional mindset is out there, allergies are just something that happens. And there’s nothing I can do besides just take the over the counter, or the prescription allergy meds. And that’s it. And that’s as far as the conversation goes, which is kind of sad, because I would argue for many people, we’ve seen hundreds and hundreds of cases of people who actually were able to get off of their allergy meds or at least significantly reduce the dosing of them by addressing the root cause, which is what these drugs do not do, they do not address the root cause of these issues. They just help modulate the symptoms, whether it’s working on the histamine issue, or some sort of immune modulating effect, or potentially steroids, but none of that’s root cause. 

Dr. Justin Marchegiani: 100%. And so the problem is, a lot of times with these type of environmentally sensitive patients, they’re going to be stuck on some kind of a steroid inhaler for a while, whether it’s computer or albuterol, or some kind of steroid, some kind of Singulair medication, which does some immune modulating or some kind of a, you know, h2, five ht to kind of receptor, anti histamine, right? These things all have side effects, they all have fatigue and brain fog as a potential side effect. And none of them are getting to the root issue. And the problem with like steroids, for instance, they tend to weaken your immune system as well. And then they tend to when you’re putting a whole bunch of steroids in your body every day artificially, your adrenal output may actually start going down, so then your adrenal strength starts to drop. And you may not be able to resist or deal with inflammation or stress as well. 

Evan Brand: Yeah, yeah. So let’s talk about some of like the basic foundations of this, where would you start with somebody who comes in with allergies in regards to testing, you and I are not typically going to run like a, quote, allergy test, you know, you’ll go to like a dermatology place, they’ll run like a patch test, or an allergist, may try to run testing for graphs and all of that. But to be honest, your opinion may differ. But I don’t really care what that test says about grass or pollen allergies, because that’s, that’s the immune system that can be overreacting. So I’m going to be looking more at the functional test. 

Dr. Justin Marchegiani: Yeah, so my perspective on these things, I always tell patients, I draw a line between cause and effect. Okay, causal things are things that are going to dictate and change treatment. So I put allergies, on the effect side, like it’s an artifact of something that’s happening due to other upstream issues. So as we move things around, upstream, above, below, inside out, everything works downstream and starts changing the effects. So we look at the effects, we may be able to trace them up to certain areas on the cause side, which is good to know. So I only talk about effects to the point where I can get closer to the cause and then make different causal changes, whether it’s diet lifestyle, supplement, doing different functional tests to assess the function of those underlying systems that are part of that causal link. 

Evan Brand: Check your mic, it sounds like it switched over to maybe like a headset or some other mic from the big boy. 

Dr. Justin Marchegiani: Let’s see here. I’m testing here. Now. We’re pretty good on my end.

Evan Brand: Talk into it closer. 

Dr. Justin Marchegiani: Testing, testing, one, two, yeah, there you go.

Evan Brand: Okay, I don’t know what to put, but it was on a different one. For some reason for a minute. 

Dr. Justin Marchegiani: I’ll put a little bit closer here. No problem. So the first thing I always look at when we are dealing with these kind of issues is I’m looking at inflammation. So the first kind of major lover, we’re going to change the diet. Because if we are stressed and inflamed due to inflammation in the foods, whether it’s too much processed sugar, excess omega six to omega three fatty acids, too much pro inflammatory fats from from junky conventional meats, too much carbohydrate or grains, these things are going to affect us negatively. Maybe we don’t have enough really good saturated fats or enough good omega threes, or enough you know, keeping the carbohydrates down we have too much insulin, too much inflammation. These things can affect our immune system. And the more stressed our immune system becomes the more sensitive or overly sensitive it becomes. So it’s kind of like you know, your neighbor knocks on the door and you’re like pulling out your hand gun going to your door ready to attack you being overly sensitive, right, your neighbor just wants a cup of milk, right? So I always look at it as we want to be able to respond proportionally from an immune standpoint. And part of that is is decreasing inflammation. So the first thing I look at is where is inflammation coming from. So let’s make sure inflammation from foods under control to make sure inflammation from blood sugar, how to control let’s make sure we have the really good fat soluble vitamins and not too much junky refined process, plant fatty acids. So we look at all those things make sure insulin is equal, not too much carbohydrates, cut out the grains cut out the casein written dairy all these things can be more inflammatory. So we have to look at all those vectors now. We can dive in deeper now to gut and infections and CBOE and H. pylori, but that’s the first thing I look at because that can significantly come down the immune system. Now, next, we have a lot of histamine kind of symptoms, a lot of allergy issues, skin issues, breathing issues, headache issues. We’ll also look at dropping down higher histamine foods as well. Whether it’s pork or coffee, or teas or citrus, or fermented foods, some of these foods are considered to be like the holy grail of paleo, right like oh, pasture fed bacon. Oh, that’s supposed to be good, right? Or like kombucha or sauerkraut or fermented probiotic food. Those supposed to be good things right? Well, they are but if you have a lot of histamine issues, they may be enough to put you over the top and we just got to be really careful with it. 

Evan Brand: Yeah, luckily I don’t have any outdoor allergy issues, but I have had issues with histamine foods so I am following low histamine diet and I feel really good on it. I feel much more clear headed. You know, excess histamine can really affect your, your your mind to like in terms of emotions. Let me share my screen real quick before we leave the diet conversation, because this is something pretty new to me. But something I’ve been experimenting with clients, and it’s been going well, I’ve been looking at this, what is called oral allergy syndrome. And basically, we’ve talked about gluten cross reactivity, you and I’ve discussed this before, where this idea that certain foods like chocolate or rice or potato or corn can be cross reactive for gluten, meaning that certain foods will make the body think it’s getting exposed to gluten, so then it creates some of this antibody reaction. Now this oral allergy syndrome is kind of the same thing to gluten cross reactivity as foods are to outdoor pollens. So check this out. So it goes into like your rag weeds and mug warts and grasses and certain tree allergies that people have but there’s foods that can cross react for these tree pollens. So here’s some of the listing here. And people can just look it up for yourself oral allergy center, but these people that are complaining about their allergies, what I’m doing is I’m putting them on kind of like this oral allergy syndrome approach. So these are all the foods that are cross reactive. So look at fruits you’ve got like oranges, melons, watermelons, rahzel-

Dr. Justin Marchegiani: Those are high in histamine though, right? Yeah, a lot of those are very high histamine. So that makes sense. They’re almost all high histamine. 

Evan Brand: Yeah, let me zoom in here. So then you go into your vegetables. Once again, these are gonna be like corn can be high histamine, so compiz. And then you go into like your nuts. So like hazelnuts and walnuts, you’ve got chickpeas, you’ve got almonds, which are interesting. I feel fine with almonds. I’ve had some people get off of them. And they feel better, though. So anyway, when you look at symptoms of this oral allergy thing, it’s itching of the throat, mouth, lips or tongue, it’s swelling. And then of course, it can be more severe. hives, asthma can be involved anyway. So So yeah, so you’re right. It’s kind of like a low histamine approach with a club basically auto.

Dr. Justin Marchegiani: It’s basically autoimmune. Low histamine.

Evan Brand: That’s right.

Dr. Justin Marchegiani: That’s basically what it is, which is good. That’s a good first kind of template because you cut out people I see a lot of patients are like, but I’ve I don’t have an autoimmune condition. Why should I do an autoimmune diet? It’s like, well, because an autoimmune diet isn’t just specifically needed for autoimmune patients. And autoimmune diet is kind of like the ultimate anti inflammatory diet. And people that have autoimmune issues, they need the ultimate anti inflammatory diet because they have excess inflammation. And their immune system is part of the reason why that is because their immune system is joining in the attack. It’s like you got self attack, it’s like you just got beaten up. And then now you’re punching yourself as well. Right? You beat yourself up. And so the more we can reduce inflammation, just think of an autoimmune diet as the ultimate anti inflammatory diet. And it’s independent of whether you have a diagnosed autoimmune condition or not. 

Evan Brand: Yeah, yeah. So we, you know, we personally and clinically implement that a lot and, and it works great for people. Okay, so let’s move on. Let’s go into some of the other stuff. You know, you and I’ve talked about this bucket analogy, and I would argue the outdoor environmental allergies are really just a sign that the, the bucket is already full, so they can’t handle the outdoor environment. I mean, our ancestors, they were outside all the time. They probably didn’t have these allergy issues. Why do we have them? Why are allergies in kids such a huge thing now? Why are so many kids on inhalers and stuff? I mean, this is not something that’s happened until the last hundred years and I would argue toxins are going to be a big one. So if we’re talking pesticides in the food, if we’re talking The impact on the gut with regards to the pesticide killing off the good bacteria in the gut, and then you’ve got kids with bacterial overgrowth. As you and I did a whole podcast on cebo. And histamine, we know there’s a huge link between bacterial overgrowth and histamine problem. So meaning your buckets already going to be so full just based on you having overgrowth of bad guys in the gut, what if your kids had ear infections, you put them on antibiotics, and then they have an overgrowth of bad guys and potential yeast like Candida problems as well, that’s already going to fill up the bucket so much, they’re not going to tolerate the outside. 

Dr. Justin Marchegiani: Exactly. So we have kind of the diet stuff change, that’s gonna make a big difference, right, autoimmune, low histamine, we’re gonna look at the gut, right? People that have histamine issues or allergies, they tend to have poor digestion. So even a healthy diet, with foods not broken down properly, may be an issue. So we may want to work on good digestive support enzymes acids, we’re going to want to look at the gut, like you mentioned, if they have a lot of, let’s say, mold or mycotoxins coming in from their home, that could be a stressor, they have a lot of yeast or Candida that could be a mycotoxin stressor as well. They have si Bo, or H. pylori, that could be a stressor to all of these things can be potential stressors on the gut side. So we’ll kind of set the table with all the first the first things I mentioned, we’ll work on getting the digestion better. And then we’ll look at seeing what’s going on in the guts. Now, in the meantime, as a couple of palliative things we can do, we can also get them on some natural histamine to granulators things that help us to break down histamine. So it’s not going to be hanging around us and creating inflammation. So those things could be stinging nettle, of course, the tender, Bromo leaner and acetyl cysteine, I have a product called our clear with a lot of those in there, that’s a great product, that’s great. We may also add in some da o which is dye aiming oxidase, it’s an enzyme found in kidney tissue. And it’s very effective at breaking down histamine as well. So we may add some of those one to two things in there, which are very helpful. And the next thing on top of that is doing some sinus rinsing techniques. Because what happens is, a lot of times the allergens, they sit up in your frontal sinus, or your maxillary sinus here in these areas here and here, frontal and maxillary, and they just sit there, and then your immune system is constantly exposed to it, it’s like being dirty, the dirts on your skin you haven’t showered. So think of is you’re doing a shower for your sinuses to flush these things out, because the top of the shower is not going to hit the insides. So the more immune sensitive you are, the more these allergens sit inside your maxillary or frontal sinus, there’s gonna be problems. So we’re going to be flushing that out two to three seconds with each nose with a really good sinus rinse bottle, two to three seconds of flow, kind of blowing your nose in between to really flush that out. And we’ll have a good filter that is still water with some kind of a mineral solution. So it’s pH balance, and some kind of xylitol or biofilm the structure to flush and break down some of that bacteria or mold junk that could be or it just allergens that could be up in your sinuses.

Evan Brand: Yeah. And how you know that you have an issue with that is if you do a sinus rent, and you have an increase or a decrease in symptoms, so any change at all. Now, some may not notice much and you’re still doing yourself a favor. However, most people that are already pretty hyper sensitized, they do notice a significant change. So what made us what that may look like could be an increase in brain fog. It could be anxiety, it could be some vision changes, it could be all of a sudden you feel more clear headed your mind your thoughts are more clear. So when I first started doing sinus rinses, I was just really like almost drunk. I was like whoa, I must have just started breaking down biofilm killing something off in there. Now I do the scientists rinse and I get more clarity. So that’s something you want to look for and silver. Some people use silver up the nose, there are some nasal sprays that have some silver hydrosol in there. You mentioned they actually are essential oil blends. There’s a couple that you and I use that are designed for the sinuses. So those can be really helpful. And like you mentioned, it’s going to be kind of draining the bucket. So if you clean up the diet, if you’re working on the gut infections if you’re going organic, and then now you’re doing sinus rinsing, you’ve already and you’re doing the herbal anti histamines, like you’re talking about vitamin C, I want to throw that in as well vitamin C can help to break ground. Or it can kind of speed up the degradation of the histamine. So for me, if I know there’s going to be a high histamine meal, I’ll do a little bit of the DA o or some vitamin C and or course attend beforehand, and it can really really help blunt the effects of it so histamines addicting to I mean, it is a neurotransmitter. So it’s really tough for certain people, when they go low histamine, they’ll start to crave high histamine foods. And that’s a pretty interesting phenomenon that I’ve seen. And like chocolate, you know, in general is going to be higher his domain and so a lot of people really have cravings for chocolate ramp up once on a low histamine diet. 

Dr. Justin Marchegiani: And as we get the inflammation under control, we’re flushing out some of the sinus stuff. Oh, also, we may also get a really good high quality air filter to get the environment really clean. Maybe there’s a lot of pollens or cedar in your home. Maybe there’s some mold toxins. We get That flushed out in the air, we get some of the food under control, we get some natural anti histamine support, we work on better digestion, get the inflammation in the diet, get rid of some of the gut stuff that’s going on some of the gut infections or gut permeability stressors, and we can start to add certain foods back in over the next few months. So this is not like a death sentence. And it always comes down to like histamine load, right? Maybe with all those other things in the past you had you’re gonna have symptoms, right. But as soon as we’re flushing out the nose, changing the diet, adding that support may be able to start getting some foods back in one at a time. So we just got to keep an eye on that. 

Evan Brand: Yep, yeah, in the air purifiers are huge. I mean, I would not live in a house period, no matter how clean new beautiful the houses, I would never live in any house that doesn’t have an air purifier. So I know you’ve got one in your office, I’ve got one in my office bedrooms, living areas. We’ve got them everywhere. I mean, and I’m not in the city, but I still want to make sure that I’ve got good filtration. And so we love and use the Austin’s so-

Dr. Justin Marchegiani: Yep, we have, we have the Austin air too. So we’ll put the links down below Evan, for kind of the links for our sites, if you guys want to support the show or want to get a high quality air filter, like we probably recommend the same, the healthmate Plus is a good first start. Or if you’re really sensitive, the allergy machine is a good second one. But the helpmate plus is my favorite. 

Evan Brand: Yeah, I mean, in terms of bang for your buck, that one’s the best one, I’ve got the molecule too. We’ve talked about this in the past, but the molecule is different technology, the blue light on it is kind of annoying, especially at night, because you’re getting blasted by the light. So you’ve got it pretty much turn that thing off or put it on dark mode at night, which then all that means is it’s just running the pre filter, which essentially does nothing. And there is sort of a plasticky smell, due to the way it kills the VCs and such on the molecule. So the molecules, you could call it more of a chemical treatment of your air where it basically breaks up pollutants and toxins and kind of destroys them into really small particles versus the Austin is more of a good catcher’s mitt. So that’s why we prefer that one. 

Dr. Justin Marchegiani: Yeah, the molecule has the light, the PET technology, the photo electronic light in there, which isn’t the best for bedrooms, because you don’t want those lights active. So we’ll use the Austin air, helpmate plus, which has the 15 pounds of zeolite. And activated charcoal 30 pounds total, also has the habit attached to it. And then it has the potassium chloride in there as well that filters out the voc. So that’s what makes it a little bit more unique. The right yes, mate doesn’t have the regular helpmate doesn’t have the potassium component. 

Evan Brand: Yeah, it’s incredible. I mean, that thing is so heavy, it literally feels like it’s like military grade, people throw that term around. But that thing is heavy duty. 

Dr. Justin Marchegiani: It is like I have some filter, I have some shelves just put into my office here. And they’re off gassing a little bit. So last night, I kept the Austin on high just to filter out any VOC’s that are, you know, in the air because of the off gassing.

Evan Brand: Yeah, let’s go into the VOC’s for a minute because you know, we kind of got off the histamine topic. So yeah, you mentioned reducing the load. Now, if you’re in a new home, and you were not extremely anal about all of your choices, there’s going to be potential formaldehyde, there’s going to be vlccs volatile organic compounds that are going to come off of your paint. If you have vinyl windows, they’re going to come off of your window frames. They’re any glues that were used on your plumbing fixtures, any of your baseboards that were painted any of your cabinetry in your kitchen that was pre finished or pre painted from the factory that comes in that stuff can off gas for literally years. And now we build our houses so tight and so energy efficient, which saves us a little bit of money, but now the houses don’t breathe. And so now these vo C’s even the EPA says indoor air pollution is 10 to 100 times more toxic than outdoor air pollution. And so I’m extremely anal and I’m actually building a course out on like healthy homes, because I’ve had to pick and choose like a lot of materials. But the long story short it and paints to even low or no VOC paints like Sherwin Williams and however you pronounce it, some of those conventional brands. They’re still toxic. Yes, they may say low or no voc, but they’re still toxic chemical. So you only want to use mineral based paints, just and I’ve talked about Roma bio, being a good mineral paint. That stuff is amazing. And then drywall too. I mean, you’ve got different chemicals that could be in certain dry walls. If they’re not gypsum based. They’re going to be synthetic. You’ve got flooring, chemicals. So you’ve got seals, you’ve got varnishes you’ve got clear coats on stuff. If you have like wood wood beams, I mean, it’s easy to fill a house with toxins is all I’m saying. 

Dr. Justin Marchegiani: Yeah, I mean, just if you’re going to do painting or any of that stuff, right, just make sure you’re out of that room. Like when we do any painting. We try to be out of the room and we just put a really good air filter in that room and put it on high and just do your best to suck out the vo C’s may off gas for a while. But if you have a good vo C on there, a good voc air filter on there you should be okay. And then just you know, take your good natural support. It’s hard to avoid these things at some time. And then the more sensitive you are the more it’s an issue the less sensitive less of an issue but just have a good air filter in the background. So you’re sucking all these things up. And then of course would be some of the flame retardant things you may get on couches or Especially you see it on kids stuff, a lot of kids mattresses, carrying, you know, car seats, those kind of things. So we always get flame retardant free. That’s the pbds polybrominated diphenyl ethers, which are the flame retardants, so we’d always get those things pbde free. And then we just have a really good air filter, if something does have it, so we’re filtering it up. 

Evan Brand: Yeah, it’s even in kids pajamas, which is just unbelievable. We had some clothes that were gifted to us for when our when our girls were really little, and it would say flame resistant. On the tag, we’re like, oh, my god, they’re putting flame retardants and kids clothing like this is unbelievable, because those are very hard chemicals to get out of the body. In fact, cola Starmie in a binder you can use for mold toxin is one of the only things that actually gets these flame retardants out of your bloodstream and out of your brain. So it’s pretty unbelievable that these things are everywhere. And so not to divert into the toxin podcast. But that’s the note about lowering your toxin load in your home to lower your bucket so that you can tolerate the outdoor environment better. 

Dr. Justin Marchegiani: Exactly. So the first thing that we like to do is make sure we decrease inflammation in our body. That’s the first thing, we may look at digestion, look at the gut, look at the microbiome, look at things that are jacking up our immune system. Of course, if cortisol is out of balance, either extremely high or extremely low that could throw things off. We may also look at strategizing sinus flushing, I have a video on that, we’ll put that video in the show notes, you can actually watch me doing an actual protocol, getting the air filtration dialed in. If you’re going to use paints with off gassing, just try to leave their home for a day or two and have a good air filter. And those are all good strategies. And then after that would be you know, changing the diet, adding in some natural anti histamine support and kind of going from there and start with the low hanging fruit. If you have problems, get a good functional medicine doctor in there to really look at investigate come up with a plan for you.

Evan Brand: Yeah, it can go a lot deeper than that. So we’ve done podcasts on these individual things. But mast cell issues, mast cells are part of the immune system that release histamine, your mast cells can become activated when you get exposed to some sort of a pathogen or a toxin. So Lyme, bartonella, mold, these are three big ones that trigger the mast cells to dump more histamine, those are big triggers. For me, I used to not have histamine issues at all. And then I developed some getting much, much better all the time. But, you know, there was kind of a straw that broke the camel’s back for me. And so I’ve dealt with it personally. But you know, we see it a lot clinically too. So you got to dig deeper if some of the low hanging fruit is not being addressed, or you got to do that first. But then once it is addressed, if you still have problems, and there is probably something deeper heavy metals, other types of toxins, you got to you got to fix all of it. So you can’t just go pop the course attend and go gluten free. And everything’s magical. For some people, it may be that easy. But the people that Justin and I are working with, they’re people that have been to 5 10 15 20 doctors before they get to us. So these people have probably already dialed into low hanging fruit. And that’s why we’re here clinically. 

Dr. Justin Marchegiani: I find with those people, they tend to have a lot of environmental stuff, there may be some mold in their system, they may have some air, they may have some air quality issues. And they may have a lot of gut issues. Because the more you’re 80% of your immune system in your gut. And so if your guts permeable and you have gut stressors, and you’re not digesting foods, well, that’s going to create more gut stress, more immune stress, the more immune stress you have, it’s because your guts more permeable, and then you’re just everything that you’re getting exposed to on the outer world is getting interacted with by your immune system. And normally we’d have some kind of a barrier protection. But now everything’s everything is now responding to your body and your immune system is seeing all of it and that can be a problem when normally there’d be some kind of a mucosal barrier protection. Now, there’s not that protective barrier is now gone. It’s like the front door is now unlocked, so your immune get exposed to a lot of things that it normally wouldn’t that gut permeability is a big, big first thing we have to look at. 

Evan Brand: Definitely, definitely. So there is a place for gut healing nutrients. There is a place for probiotics like we use a lot of Bifido really, really high dose Bifido can be helpful. spore based probiotics can be helpful. Medicinal mushrooms can be helpful to help modulate the immune system. We like herbs too. There’s Andrographis and Astragulus and elderberry. And I mean, there’s a ton that we could go into these can be helpful, it really just depends on where somebody is at because you can send the immune system the wrong direction. So an autoimmune cases and such there are some times where we may not go straight to mushrooms, we may just focus on the gut first. But once again, it’s kind of a case by case basis here.

Dr. Justin Marchegiani: Yeah, exactly. Anything else you want to add today?

Evan Brand: I would just tell people that there are answers, there are solutions to this. So if your allergist is not getting to the root cause then feel free to reach out to one of us. We’d be happy to take you to the next level of healing. Look into the gut look into all of these different body systems kind of get your total body burden figured out, and then we’ll help plot the step one, step two, step three, how to get you feeling better. So if you need help clinically, don’t hesitate please reach out to Dr. Justin at or me Evan Brand at We’re here for you guys. So we love helping you we’re extremely blessed with the knowledge we’ve gained, you know, personally and clinically, and it’s very rewarding to get people relief. That’s the that’s what this whole entire episode was about relief. It’s not fun when you want to go hike with your kids or grandkids and you can’t because you’re miserable. And then you got to do your inhaler, because you can’t breathe. I mean, God, that’s just not a way to live. And there is there is there was there is a way out of it. So that’s what we’re here for. 

Dr. Justin Marchegiani: Excellent. Well really appreciate today’s chat if you guys want to reach in for Dr. Evan and for myself, we’ll be happy to connect with you all and kind of go over the different algorithms and what’s going on underneath the hood so we can get to a lasting solution. Hey, Evan, great chatting with you, man. You have an awesome day. We’ll be in touch. 

Evan Brand: You too. Take care now. 

Dr. Justin Marchegiani: Take care, bye.


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Allergies and Your Immune System

Allergies and Your Immune System

By Dr. Justin Marchegiani

Spring is here and so are allergies! This is the time of year were allergies are in great abundance. Flowers are in bloom so our grasses and many other types of pollen that our immune system has not been exposed to the last six months or so. When our body is being exposed to these environmental compounds, it is responding to them as if they are a foreign invader, like a bacteria or a virus. We know this is an inappropriate immune response; these environmental compounds are not out to hurt us. Our immune system is being overly sensitive; we need our immune systems to calm down so it can be more intelligent and pick out the real immune threats from the benign ones.

There are certain things we can do to help make our immune system more intelligent. Eating an anti-inflammatory diet is very helpful, this helps take stress off the immune system, it helps lower cortisol, it helps our immune system stay strong and smart so it can pick out the bad invaders from the not so bad. When we are overtired it’s common for us to overreact during certain situations. This analogy holds true for our immune system, the more inflamed we are, the increased chance our immune system will overreact.

Medication and allergies

 Medication and Allergies


The majority of medications that help with allergies such as Zyrtec, Allegra, Singulair and Benadryl usually work one of two ways; they suppress the immune response and or weaken the immune system or decrease the histamine response. If you are the kind of person that is interested in having optimal health the two pharmaceutical alternatives mentioned above don’t sound too great. It’s much better to make the immune system smarter and more intelligent and not just weaker and docile. Anytime you weaken the immune system you make yourself more susceptible to other chronic degenerative diseases.

Click here to find out how you can improve your immune system.

Some of the above drugs have side effects involving weight gain. Many patients I know are trying to lose weight, and are more than likely not aware that some of the medications they are using maybe potentially antagonizing their weight loss and body composition goals.


Some of my favorite natural compounds to help address allergies and inflammation

 Compounds of allergies

Quercetin: Is a bioflavonoid and it’s very helpful in helping in balance out the immune system, quercetin helps decrease inflammation as well as decrease your body’s histamine response. Histamine is what makes your body stuffy, congested, and makes your nose runny. This provides a natural solution for people that may have use Benadryl or other types of algae-based medications. Quercetin also has no side effects and is a powerful antioxidant as well.

NAC (n-acetyl cysteine): NAC is a sulfur-based amino acid that is a precursor for glutathione. Glutathione is our body’s master antioxidant and is primarily used to help quelch the fire of inflammation and free radical stress. The more stressed we are the more our antioxidant and glutathione systems are taxed and the increased chance our glutathione reserves will be depleted.

Many people out there aren’t eating enough high-quality protein sources and cruciferous vegetables such as broccoli, asparagus and cauliflower. If we don’t have the raw material amino acids to help make glutathione we have an increased risk of being overly inflamed and being susceptible to allergy symptoms as well.

Fish oil is an essential fatty acid in the omega 3 family which increases the prostaglandin 3 pathway (it’s highlighted in the picture below).  This pathway is anti-inflammatory and helps put out the fire in our body.  Avoiding refined omega 6 fats like vegetable oils like canola, soy, and cotton seed oil to name only a few can help decrease our prostaglandin 2 pathways which make us more inflamed.  As inflammation increases so does our chance of allergies.  Eating foods that help put out the fire and avoiding foods that help increase the fire is an easy way to help improve your allergies.

Consuming 4-8 grams of high quality fish oil that is in a triglyceride form tends to be the best.  Make sure you are consuming a high quality brand.  If your are burping up the fish oil, the brand may not be of good quality or your body isn’t producing enough enzymes to break down the fat.  A fish oil with lipase included can help decrease this problem.  To get to the root cause of your allergies, click here!




The entire contents of this website are based upon the opinions of Dr. Justin Marchegiani unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Justin and his community. Dr. Justin encourages you to make your own health care decisions based upon your research and in partnership with a qualified healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Dr. Marchegiani’s products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products.