Fibromyalgia Natural Solutions – Dr. J Live Podcast #159

Dr. Justin Marchegiani and Evan Brand discuss about Fibromyalgia including its cause and symptoms. Learn how some of the symptoms connected to it such as anxiety, depression, IBS, memory problems are also seen in other health conditions.

Listen as they talk about some of the viruses, infections, gut health, heavy metals, thyroid and adrenal imbalances as possible contributing factors or underlying issues leading to unfavorable health symptoms. Gain some valuable information regarding natural solutions and lifestyle changes that you can do to combat these symptoms.

 Natural Solutions for Fibromyalgia

In this episode, we cover:

 

02:15   Fibromyalgia Symptoms

03:48   Viruses and Infections

07:20   Gut Health

10:31   Adrenal Issues

13:19   Heavy Metals

 

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Dr. Justin Marchegiani: It’s Dr. J here in the house. Evan, how we doing today? Happy Monday!

Evan Brand: Hey, man!  Happy Monday to you. Life is good.

Dr. Justin Marchegiani: Yeah. We had a little technical difficulty here. But we are rolling. The show must go on. So, any any updates for me here that you want to bring to my attention before we dig in and get dirty?

Evan Brand: Well, I’m just excited. I’m excited to talk with you about fibromyalgia. This is one of those things in that category like IBS where the conventional doctors—

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand:.. give people diagnosis and then they just end up with drugs in their pockets and they don’t have any real success. And people struggle for years and years and years, they end up with these other symptoms that come along with fibromyalgia like anxiety or depression or IBS. And once again, conventional Docs, they just don’t really have a high success rate with this issue.

Dr. Justin Marchegiani: A hundred percent agree. And fibromyalgia is one of these interesting types of diagnoses. Basically you have to have uh—central allodynia pain, which is kind of like this uh— pain that may be true like 11 different random spots of the body. So they look for these different pain, tender spots, shoulders, chest, hips, back. And they are looking for like at least 11 out of the 17 or so spots. And if you have it, great, you have fibromyalgia, right? Coz basically what is a central allodynia? That means your nervous system is so hypersensitive that it’s dectecting, you know, you rubbing like this, just things that shouldn’t cause pain. It’s sensing that it’s pain. And that’s the biggest issue coz  the nervous system is so upregulated, it’s like having an antenna that’s so hypersensitive that it’s picking up stations uhm— that shouldn’t be picking up.  And it’s the same kinda thing. Your nervous system is an antenna that’s picking up all these nociception or pain sensation where it shouldn’t be. So we want to get to the root cause of why that is. Go ahead.

Evan Brand: Yeah. There is uh—conventional drug that a lot of people end up on. The Lyrica, which I’m sure you’ve heard of.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: Huge pricing commercials for it. And I’ve had people taking that and they just don’t notice much and then sometimes the side effects, maybe not without drug, buy any of the drugs, can be worse than the actual thing that you’re trying to fix into the first place. So that’s just— it’s scary because when you want to get a root cause answered, you’re not gonna get it unless you start running some of these functional medicine testing that we’re talking about. So I just have a list of symptoms I wanted to read that could come along with the fibromyalgia. So that could be anxiety, that could be concentration and memory problems, depression, fatigue, headaches, irritable bowel syndrome. Now, that sounds like a lot of other things that we need to talk about.

Dr. Justin Marchegiani: Exactly. And here’s the thing, right? A lot of people may have gluten sensitivity or hypothyroidism or heavy metal issues or gut microbial imbalances, the issue is that some people may manifest with Hashimoto’s. Some may manifest with fibromyalgia symptoms who have a lot of the central allodynia pain. So it is interesting because some people, they can have the exact same core underlying issue, but have a totally different diagnosis. And all of diagnoses is a constellation of symptoms that are typically put into one category, right? The chronic pain symptoms—that’s gonna be in the fibromyalgia category. Memory symptoms—that’s gonna be in the category. Fatigue symptoms— that could be in the thyroid or adrenal category. Gut issues— depending on where that inflammation is located, that could be in the Crohn’s or Ulcerative Colitis or there’s no inflammation in the tissues that can be in the IBS category like you. So this is where it’s tough because all conventional medicine is tyring to categorize known symptoms in the categories call the “disease”. We are trying to trace it upstream. And the hard part about functional medicine is certain people can have the exact same imbalances and manifest with totally separate diseases. That’s the hardest part people to wrap their heads around.

Evan Brand: Yeah. Let’s go into the viruses. My wife when she had joint pain several years ago, you said, “Evan, the first thing you need to look into is going to be some of the viruses.” And so we got a blood test run on her. She did not show up with Lyme, fortunately, but she did show up with the cytomegalovirus and then also the mycoplasma. Can— so can you speak about those a bit? And how that could be causing joint pain that could get misdiagnosed?

Dr. Justin Marchegiani: A hundred percent. So there are certain infections like mycoplasma is one of them they can manifest in the joint tissue, for sure. So that’s one of those conditions that an infection can really be driving a lot of that joint pain. And we know certain infections and certain imbalances can manifest with certain symptoms. Like we know that hypothyroid issues, low thyroid function can manifest having low thyroid hormone in joint pain. We also know like infections like mycoplasma can also cause or call  the lower thyroid function and then potentially manifest in joint pain. We also know it could potentially manifest in the joints and you know certain antibiotics like Minocycline to help knock it out. We prefer to use some of the herbs coz it tends to be safer on the gut microbiome in the long run, number one. And then with your wife symptoms, we notice that she already had a pretty good diet.  And there was a tick bite involved in your wife’s last issues. Is that correct?

Evan Brand: That’s right.

Dr. Justin Marchegiani: And so because of that, you know, we were leaning towards, “Hey, let’s just to after the infection and see what happens.” And when we knocked out the infection, everything got a lot better. So that was good to see that.

Evan Brand: Yeah. It was so— it was so it was so easy, too. So simple. Just modify the immune system, all of a sudden things are better. So, if you have fibromyalgia or you have joint pain and general pain stiffness, you gotta make sure you roll those in. So go to your doctor if you’ve got a natural path or functional medicine practitioner, that’s even better. Try to get them to test you for the Lyme, plus the co-infection. So coz like I said she had a negative result for Lyme, but she was positive for these other things, Cytomegalo and the Mycoplasma. So you gotta go look for them.

Dr. Justin Marchegiani: Hundred percent. So, again, any issue any like disease issue, like if you’re someone and we’re focusing on fibromyalgia today because that’s got a certain bit of symptoms that manifest in pain. So if you resonate with that, great. This is going to help you. If you don’t resonate with fibromyalgia symptoms, but you have something else, this podcast is still gonna be helpful because we always trace it back to the underlying imbalances, which can manifest itself in different symptoms. But one thing that’s gonna be uniform across the board is looking at the gut. The gut is really important coz that’s where a lot of your immune system is. 70 to 80% that’s where your body digests and breaks down nutrients, that’s where uhm—your— essentially you digest and break down all the food you’re eating. So if we’ve a bottleneck in the breakdown of our nutrition, we’ve a bottleneck in how our immune system functions, if we have a leaky gut and your immune system’s being overreactive, or if we have an infection there, that can create a lot of underlying stress that may manifest itself in different symptoms. And again, kinda linking it back to fibromyalgia, if you have these chronic pain issues, those 11 kind of places a central allodynia pain to touch, right? Your diagnosed 11 places of pain on your body, at least. And you have the fibromyalgia, the diagnosis, then we definitely have to rule out the gut. And again, here’s a thing that really throws people for a loop is that you can have gut issues and not have gut symptoms – that’s the really hard thing. You may not have the bloating, the gas, the diarrhea, the constipation, the acid reflux, and you may still have a gut issue.

Evan Brand: Uh-hmm. H. pylori we see it every week in the clinic. So if you’ve got H.Pylori, you’ve got that bacterial infection, that’s suppressing HCl production, therefore you’re not digesting your food. So if you’re seen floating stools or you’re seeing undigested food particles in your stool, that could all be adding up to this whole picture of the depression, the anxiety, the fatigue. Maybe even skin issues, too. So maybe you don’t have the fibromyalgia diagnoses, but you’ve got fatigue, depression, anxiety maybe some sleep problems maybe some skin issues. That could all be tied into leaky gut— that intestinal permeability. It could be something as simple as H. pylori or like Dr. Justin Marchegianientioned, it could be H. pylori plus Mycoplasma plus maybe some bacterial overgrowth like the SIBO case or plus parasites, which is something we often talk about, plus fungus. You know, typically it’s not just one thing. Most of the time, by the time people get to us, they’ve been suffering for quite a long time and therefore, there’s usually a handful of things that we’ve got to address. Now on the thyroid, is the pain going away just a side effect of you fixing your thyroid? Like all the sudden thyroid function improves and the pain just goes away. Could it be that simple if that were your biggest root cause?

Dr. Justin Marchegiani: Well 100%. So you can see it quite frequently that just getting someone on some T3, some thyroid hormone can really help because they may be on thyroid hormone, T4, but they’re not able to convert and activate it. So there’s TSH, right? The pituitary hormone that most conventional docs measure to look at thyroid function may look nice and pretty but they’re not making that conversion from T4 to T3. So their T3 levels may be low, and if you come in there with some activated T3, you may start to put some of their thyroid symptoms on remission. Now, we have to understand, from a functional medicine perspective, what’s palliative and what’s root cause. So we have to make sure we actually fix the underlying conversion issues, if it’s nutrient or if it’s inflammationm if it’s gut, if it’s immune. And we also had to fix the underlying nutrient absorption issues, the infections, the autoimmunity, right? So whatever those issues are. So, we kinda understand that there are certain natural medicine things we can do. There are palliative, which are great. And there are certain things like, I think you mentioned earlier about the uhm—your child has a little bit of eczema and you know, putting a little bit of coconut oil in there helps. But you recognize, that’s palliative not root cause. So we try to get to the underlying foods that may be causing it.  Same thing in this analogy with thyroid. And thyroid, low thyroid hormone can express itself in about 70 different symptoms—hair loss, fatigue, uhm— brain fog, anxiety, right? All these different symptoms. Also, the pain symptom is one of the.

Evan Brand: Yup. Well said. And if it’s Hashimoto’s, if it’s an autoimmune thyroid condition, that T3 could help symptoms improve. In this case, you could get more energy, could help reduce pain. But if you haven’t stop that autoimmune attack by addressing infection, supporting the adrenal glands, making sure the diet is dialled in, and you don’t have any foods that are creating antibodies against the thyroid. You know, those are some of the big three needlemovers you got to have on board to fix this thing at the root and not just be stuck on T4 or T3 or combination for the rest your life.

Dr. Justin Marchegiani: Hundred percent. So we also know that adrenal issues— adrenal imbalance is not necessarily adrenal fatigue, of course, you know, most people in the conventional medical world will hear adrenal fatigue and think adrenal failure like Addison’s disease, okay? Which is valid but we also know that there can be imbalances in cortisol that may not be a full disease failure kind of situation. It may be just lower adrenal cortisol issues, lower DHEA because of HPA axis dysfunction. And if that’s the case, we want to make sure we support that because adrenal, zero adrenal glands produce cortisol, which is your natural anti-inflammatory hormone. And again, people that have chronic pain issues, a lot of times, we put on like COX 2 inhibitors, things like that. Severe pain, of course, Opioids is an Oxycontin, which is a another big issue in itself. But also, Prednisone and Corticosteroid drugs that basically have the ability to knock down inflammation, the problem is, why aren’t your own glands working enough to cover up that inflammation, too? So, if we get the adrenals working better, we can kinda make some of our own homemade Prednisone on our own—our own homemade Corticosteroids to help cut that inflammation down.

Evan Brand: So talk about what happens. Let’s say somebody is on the steroids long-term, that’s also going to affect the adrenals as we’ve seen on some lab results.

Dr. Justin Marchegiani: Yeah. It will throw off some of the feedback loop, so will disrupt the HPA axis, that’s the brain talking to the adrenals. That’s that nice feedback loop or that kind of internal thermostat that our body has. So we do have that there that we have to work on because that can affect that thermostat. Uhm—number two, it can really throw off your blood sugar. So taking a lot of synthetic steroids that when we create protocols for a patient, we may use small amounts of precursor hormones like Pregnenolone or DHEA. And these are gonna throw things off in the same way that a drug would. Because these drugs are very, very powerful. They can mess up the feedback loops. But if you’re using a corticosteroid, it can really mess up your blood sugar and in the long run, it can even create osteoporotic situations. It can really thin out the bones. It can really weaken the gut lining because these steroids break things down,right? They’re anti-inflammatory but they are also very catabolic. So it’s great in the short run, right? When we get back on track, but not good in the long run coz it can really mess up our glandular physiology. How that—how our hormonal systems work. And the feedback loops that kinda keep them connected.

Evan Brand: I think it’s worth mentioning heavy metals, too. I don’t think it’s good to be

necessarily the number one cause for most people, but we notice that if there is a gut issue, let’s say somebody does have these gut bugs, they could have a detox problems, too. Just coz their body, their liver is just so overburden. Let’s talk about metals a bit. So could be just amalgam fillings or could be occupational exposure or could be too much of a lower quality or too big of a fish like a tuna that’s causing issues. Let’s talk about that for a minute.

Dr. Justin Marchegiani: 100%. So we can definitely have toxicity issues like Mercury which can be very inflammatory. Mercury also is similar to the halide group so it could fit into the receptor site where Iodine would typically bind in. Fluoride and bromine can also pinch-hit there as well. So that can create a lot of issues regarding that. Mercury can also jam up the mitochondria. I mean feel free and go to PubMed and just type in “Mercury and mitochondrial function” and you’ll see increase in heavy metals can decrease mitochondrial function. And again, as—as glycolysis and our Krebs cycle turns and we have betaoxidation on the flipside, we generate about 36 ATP’s per pump and those ATP’s work is kind of the cellular currency for energy, right? It’s how our body kind of you know, creates energy and you know, has aerobic metabolism to create ATP, which is our body functions and that’s kinda the byproduct of having a healthy metabolism.

But if we go in there and all these gears are moving spitting out all these ATP, which is basically cellular energy, and we messed that up, we throw kind of a monkey wrench into the gearbox, that’s gonna prevent optimal ATP function, which is gonna throw off our energy and our body ability—our body’s ability to function, right? Lower energy is gonna create symptoms. Anytime you have lower energy, you  tend to start having brain fog issues, mood issues, fatigue issues, pain issues, sleep issues because energy is the byproduct of a healthy metabolism. So when energy goes, metabolism is going down. And when that’s starts to go, other symptoms tend to manifest as well.

Evan Brand: Yeah. I’ve gotta say two things. One is glyphosate. If you’re not 100% organic, make your goal to be a 100% organic as close as you possibly can. I love that people are honest. I had a guy who on his intake form, I asked the question, “What percentage or diet is organic?” He said 0%. I’m like, “Man, you’re getting glyphosate.” We can measure it. We can prove it on a piece paper, but just know if something is not labeled organic, especially your fruits and veggies, assume it’s contaminated with glyphosate. Just like Justin mentioned about Mercury, antibiotics, glyphosate. Those are all mitochondrial killers and so there’s nothing worse that you could possibly do than have glyphosate in your system. Now, fortunately, you can detox it by using the sauna. There’s other methods that we talked about but just make it a goal. Throw out the—you know, go donate or throw out the non-organic stuff. Swap it out. Pay the extra buck. Pay the extra 2 bucks. It’s gonna be much, much more valuable in the long-term and much cheaper in the long term because you’re gonna prevent yourself from having health issues associated with glyphosate toxicity.

Dr. Justin Marchegiani: Hundred percent. Hundred percent. I had a conversation with someone recently that say, “Hey, you you realize organic food doesn’t have any more nutrients than conventional food.” And I said back to them,”Well, it depends.” There are some studies that do say organic food does have more nutrients. I mean there are some people that say that’s there are some studies by Temple University that shows a much higher level in nutrition with organic food than conventional food. I just think it depends on what kind of organic we’re talking about factory farm, you know, big corporations have started labeling things organic. And again, are they gonna have the same high level as a local farm regarding fertilization, you know, rotating the crops. I mean, if you just have an organic farm without pesticides, but you just continue to heat that crop season after season, don’t let it rest, don’t switch spots, and don’t you know, add synergy to the land, right? Some synergy is like, for instance, when the cows pass on their— basically have their manure, their bowel movements, you’re bringing the chickens afterwards to kind of help uh knock out all the grubs, right? Which prevents other animals from coming in. So you can add synergy to the land that helps, number one, increase uhm— fertility to the soil, right? Increases that top soil. But number two, it helps other past and creatures from growing, which can create havoc down the line. And so, in other words, uhmm—some people can really hit that soil hard and decrease the nutrient densities of the organic food. It has less nutrients, anyway. But anyway, so let’s just pretend this person is right. They told me organic food has the same nutrition as conventional food. Alright. Fine. We do know the research is quite conclusive that organic food has less pesticide residue. Of course, coz to be organic, you can’t have pesticides on it. So just the fact that— let’s the nutrient’s density is the same from organic food. While I’m definitely not getting the pesticide exposure, which Evan mentioned earlier with Glyphosate or Roundup. It’s so important. coz there are so many studies on that coming out that it’s very toxic on the body, on the liver, on the gut. And essentially many other places.

Evan Brand: You know, the European Union, they’re successfully banning it. I’ve been trying to keep up with this is much as I can. It looks like glyphosate is seeing the end of the rope in the European Union. I hope something is to follow in the US, but I just don’t think it’s gonna be anytime soon here.

Dr. Justin Marchegiani: I agree.

Evan Brand: One of the thing I wanted to mention is on the CDC’s website about fibromyalgia, they say that much much much higher rates of ankylosing spondylitis occur with fibromyalgia and Justin and I mentioned this on a mini podcast. That’s an autoimmune condition. And so it sounds like what they’re saying without saying it because maybe they’re not noticing the link, is that this whole thing is likely just a autoimmune issue. The IBS, like you mentioned, the Crohn’s or the Colitis, the Hashimoto’s, like this could all just be autoimmunity at the root. And we’ve just got to go through all of our causes and fix the autoimmune issue and then all of a sudden you can reverse the symptoms.

Dr. Justin Marchegiani: Hundred percent. And again, there’s like over a 180 autoimmune conditions. So my analogy is anytime you have a physical chemical or emotional stress, or  you know, imagine having this fancy pearl necklace, every time you put tight, that’s a physical chemical or emotional stressor in your life. And let’s just say every little spot where that pearl connects to the necklace, they’re not all the same strength. There maybe some part to that chain that are little bit weaker. Think of that as genetic predisposition at work. You’re gonna have certain genetic links in the chain that are going to be a little bit weaker. Now what does that mean to you, as that stress comes on, that part of the chain may be more likely to break than another part. Let’s say  Pearl 33 is more likely to break them Pearl three or Pearl four, right? Now, Pearl 33 may be ankylosing spondylitis. And that stressor may be Roundup or could be Hashimoto’s or let’s say Pearl 4 is Hashimoto’s for someone else, right? So think of every little link in that chain as a different disease that could manifest if that link is broken. And where that link you for you, is gonna be based on your genetic predisposition. What we have control over is not pulling that damn chain type. Let it go. Let it relax, right? How do we do that? All of the diet and lifestyle things. Just cutting the Round up out. Eating organic. That pulls the stress off. And getting that good sleep, having good thoughts, fixing your gut, fixing infections, making sure you can digest and break down all that really good food that you’re eating. Get your hormones under control if there’s imbalances there. Does that make sense, Evan?

Evan Brand: Oh, it sure does. I mean, just like you picture a big wall think of like a submarine. You’ve got a 1000 switches in all these red switches are flipped on. We’re just gonna go down the list and just flip all those red switches off, and all of a sudden you turn off, you’ve not pulled the trigger. You’ve got the loaded gun, but we’re just gonna decide not to pull the trigger. People think that like genetic testing is the end-all be-all and “Oh, my gosh! I’m genetically predisposed to X.” It’s like that doesn’t change the protocol at all. That just means you need to be even more diligent. If your family had a history of this condition or other conditions, you just have to be more diligent. That doesn’t mean you’re toast. That doesn’t mean you’re definitely going to get XYZ disease or condition. That just mean you got pay attention. You’ve gotta make sure you’ve got all the pieces going in your favor.

Dr. Justin Marchegiani: Yeah. And I pretty much work with the genetic stuff. I don’t get so hyper fixated on it. I just assume the worst for everyone. And that way, we’re making the changes in hydration, with sleep, with water, with toxicity, with gut. We’re not gonna give synthetic folic acid. We’re gonna give super high quality methylated B vitamins. We’re just making that assumption for everyone because I can’t be hurt by making that assumption in that direction. If I make it the opposite direction and say, “Hey, it’s okay. You probably don’t have a folate issue. I’m gonna save some money and put some crappy synthetic folic acid in my multivitamin instead of high-quality activated folate. Then I can go wrong, right? I may save a little bit of money but because we’re interfacing with our patients daily and weekly, we know that we’re better off rolling the dice in favor of there being an issue with that. So we always have the higher quality nutrients in there to cover our butts.

Evan Brand: Yeah. And I had a a woman who emailed me this morning she said, “Evan, I had a reaction to gluten. Do you think it’s time that I go get tested for celiac?” And I told her, “It’s better cheaper and likely safer just to assume that you’ve got a massive allergy to gluten,” Then you just need to stay way because really, going to the gastroenterology process where they make you eat— what is it two slices of bread for like a week or two and then they cut out a piece of your intestine to try to see if all those cilia where destroyed or flattened. And then a lot of times, there’s even false negatives there. So you could do all that work. Destroy your body, create inflammation and then say, “Oh, it says negative.” It’s like just stay away and be more diligent. Don’t tell people that it’s a preference. Just tell it—  tell people at a restaurant it’s a gluten allergy. Make  they change their gloves. And you’re gonna be much safer as opposed to waiting for that diagnosis. So that’s kinda what my message is. If you have these symptoms, maybe  you’re not been officially diagnosed with fibromyalgia, but you’ve got these symptoms, you’ve got pain and the sleep and fatigue. Just go ahead and think, “Okay, maybe I’ve got XYZ but now I’ve just gotta start working on all these big pieces we talked about.

Dr. Justin Marchegiani: Hundred percent. Yeah. Makes a lot of sense. And someone’s chiming in here on the YouTube live here, chat saying that uhm—their local farmer told him it’s certified organic, allows them to spray toxic pesticides two times a year. Not sure what kind of certification that is.  Typically, the USDA certification’s pretty good. The fied has to be—the land has to be for three years without pesticides to even get that certification. So I’m not sure if we’re talking about the same USDA certification, number one. And a lot of farmers they’ll use other compounds that tend to be a little less toxic to help with spring. So like for instance we have our property done which had to use probiotic spray and we tend to use essential oils. And again, there may be chemicals in there, of course, but they may be harmonious and have less toxic burden. I’m more worried about the toxicity of the pesticides. And let’s say you bought an organic food that was, you know, in one of these farms that was spray twice a year,  well, isn’t that gonna be better than a farm that’s sprayed weekly?

Evan Brand: Right.

Dr. Justin Marchegiani: So I’m kinda like good-better-best. Hey, if I’m gonna cheat or if I have a choice option between something that was spray weekly versus twice a year, I’m still gonna go with twice a year because that toxicity burns is gonna be good. Also, we can just utilize the Clean 15 and the dirty dozen. Great, if we’re gonna buy a food that’s conventional or somewhat conventional with pesticides. Let’s look at the Clean 15 and see the foods that have less pesticide residue and avoid the dirty dozen and/or just get a really good uhm— vegetable or fruit wash that you can wash off some of the external pesticides at least.

Evan Brand: Yeah. And some of the regulations under the USDA, there’s a difference between 100% organic and just certified organic. So, obviously, the best thing to do which is contact a local farmer, which is what I do. I buy some bison meat and other products locally. And I know that they don’t ever use chemicals ever and if they do have to use chemicals, they’ll tell you. And they’ll say, why, what happened how much, what did they actually use. So if you just look up local harvest and go look up type in your ZIP Code, your location, go find some local people and just talk with them. That way, you  don’t have to guess anymore whether something’s actually legit from the grocery store. I still go to the grocery, but I try to source other things outside where I can check the person’s hand. It’s just a lot more viable experience that way.

Dr. Justin Marchegiani: Yeah. And again, we just have to do your best, right? Sometimes we don’t have the best options you know, when we’re traveling or we’re going out to eat. But if we can control the 80 to 90% when we’re home and we’re in our house and the foods that we choose in our area, that’s gonna be the most important thing. Also, when you’re healthy, you get a little bit more wiggle room; when you’re chronically sick, you don’t. So if you’re chronically sick, then you really got to be careful and make the best decision possible and uhm— if you’re not, then 10 to 20%, I’m totally okay with. And if you’re going to get exposed to things, activated charcoal is a great option uhm— taking some extra detox support may be helpful, too. So all that’s really good if you know you’re gonna be getting exposed to not so good things.

Evan Brand: Yeah. Take in your enzymes, too. Take in your acids, your enzymes. You and I both use enzymes that are gonna contain special ones that helps. So if you do get  to it. exposed to gluten, that can help reduce the flareup. If you are sensitive, you are react to it.

Dr. Justin Marchegiani: Exactly. And then James here, talks about uhm— his fatigue still lingers daily, can’t shake it. Thyroid tested good with me, uhm—Modafinil works great and gets me to the day. And Modafinil or Provigil aspirin is a big fan of it. Not a huge fan long term. I mean I think it’s not fixing any of the underlying issues. So the diet helps I mean I would look more at the adrenals, I’d look more at the mitochondria. I forget your specific case, James, I know you’re doing good for a while. So if you just had a backward slide recently, we’d wanna chat and figure out what underlying stressors have creeped up or make sure the infections are gone, or make sure the mitochondria are functioning as optimal as possible. So I wanna look a little bit deeper. I’m fine, though, using Modafinil Provigil punctuated time frames, you know, a work deadline comes up, major stressors you know, you have to induce some extra stuff on the weekend with your family or work stuff, then fine. Take that to really upregulate your body but just keep in mind there’s something deeper we got a look at. And just  you know, things like sleep and things like hydration and people forget those all the time.

Evan Brand: Yup. Very simple but sometimes the most simple stuff moves the needle.

Dr. Justin Marchegiani: Yeah. I mean Daniel talks about here, uh— talks about what can cause jellylike lumps in the semen sometimes painful to pass. Well first off, I would do like a urine analysis first, just to make sure there’s nothing, no UTI your uhm—you know, nothing that’s kidney or bladder base. Make sure there’s no infections in the piping, so to speak. Uh—again, I would also rule out epididymitis. Make sure there’s no infections in the epididymis. There could be a bacterial issue that’s just causing these uh— the semen to kinda agglutinate or stick together. And also, even just run a sperm analysis. Just to make sure this— the semen are actually alive and it’s not a whole bunch of dead semen uh— in there as well. So, I would look there first. If the diet’s good, if everything else is good, I would just make sure any type of infections and that urinary area are also clear too. E. coli, those kinda things.

Evan Brand: Awesome. Well, we gotta wrap up. Both of us gotta get back to our calls, but we hope you guys enjoy the show and leave us questions. You can leave us questions in the future. So if you didn’t catch this live, go to Justin’s YouTube channel. Go on his video, write in your questions, we’ll try to answer as many as we can or will save those for future show. And then same thing for topics. If you have topics that you want us to address, please put them on there. And if we need to reach out for a consult, check out Justin’s site. It’s Justinhealth.com You can schedule a consult. If you wanna schedule a consult with me, check out my site EvanBrand.com and we are happy and willing to help you. So please reach out if you’re suffering around the world, just phone in and Skype consults make it easy for us to help you.

Dr. Justin Marchegiani: And check us out on our podcast channels, too. We’re trying to do our videos here on YouTube, but we’re also trying to record everything in higher-quality audio. So, if you want to hear  us in some higher quality audio, check out our podcast channels. Again, if you go to Evan’s site, EvanBrand.com or my site, Justinhealth.com click on the podcast and you can subscribe to get updated, audio as well. Anything else you wanted to add, Evan?

Evan Brand: I think that’s it. Awesome and Ross, yeah, Mastic Gum is great for H. Pylori.  Awesome show today, Evan. Great as always. Appreciate your energy and your insights and let’s chat real soon.

Evan Brand: Likewise, man. Take care.

Dr. Justin Marchegiani: Take Care. Bye now.

Evan Brand: See you.

 


References:

Justinhealth.com

Evanbrand.com

 

 

 

Low Body Temperature! – Dr. J Live Podcast # 156

Dr. Justin Marchegiani and Evan Brand engage in a very informative discussion about low body temperature. Learn how different potential stressors like thyroid issues, adrenal issues, gut health, autoimmune conditions, nutrition and low calories cause low body temperature. Find out about the role of micronutrients in thyroid hormone conversion and be aware of the medications that have a negative impact on mitochondrial function.

Gain information about the different foods, including modifications in macronutrients, and various supplements, which will improve your health and prevent different stressors that are possibly causing low body temperature.

In this episode, we cover: low body temperature

03:27   Thyroid issues

07:05   Beneficial Nutrients

14:14   Toxins and Medications

22:51   Food and Supplements

33:46   Calorie Intake

 

 

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Dr. Justin Marchegiani: And we are live here on YouTube. It’s Dr. J in the house. Evan, my man, how are you doing brother?

Evan Brand: Hey man, happy Monday! We’re talking all fair about that shooting this morning so my mom, she worked right next door last night at the Hotel Luxor which was uh— right next door to that shooting event in Vegas. So I called her this morning and she’s safe and sound and she got released, so she’s home, hopefully sleeping. I’m sure she’s extremely adrenally stressed at this point, but hopefully she’s resting and settling down from all that.

Dr. Justin Marchegiani: Yeah. Lots of empathy for all the people out there going through that. It must be just incredibly stressful.

Evan Brand: It’s insane.

Dr. Justin Marchegiani: It’s just so difficult. So wishing everyone, you know, speedy recovery from that. That is just so difficult and man, everyone’s adrenals are revved up from that, right?

Evan Brand: I know.

Dr. Justin Marchegiani: So let’s go into some stuff here where people, we would get— put some information out there about improving everyone’s health.

Evan Brand: Yes.

Dr. Justin Marchegiani: Uh—and just continue to empower more people. So let’s dig in, brother.

Evan Brand: Yes. Yes, so you and I want to chat about low body temperature, which is something that so many people have. I’ve had it in the winter for a long time. I’m hoping that since I work so much, my gut and my adrenals that I don’t have it this winter but cold hands, cold feet you know that had been something that I mentioned going on with me for—for several years. I know there’s a lot of different causes that you and I wanted to go through. So how should we open this thing? Should we talk about hormones, thyroid, how do you want to lay the groundwork?

Dr. Justin Marchegiani: Oh, we look at body temperature. Temperature is probably one of the best indicators of your metabolism, right? Because the more energy you have, typically the— the better your temperature is. And so typically, you’re gonna have symptoms of cold temperature which are gonna be cold hands, cold feet those kind of things. Also, fatigue, but now there’s also objective ways that we can test your temperature. You know, with the thermometer, obviously. We can do axillary temperature, which is armpit. 97.8 to 98.2 is—is Fahrenheit is a pretty good range to be in. Or 98.2 to 98.6 orally. And so you can kind of assess your temperature. You can do it in the morning and then you can also do it in the afternoon as well. Kinda do it just for before eating. That gives you a pretty good indication but if your metabolism is low and your temperature is low, it could be caused by an interplay of different things. We’ll go into it. It could be thyroid issues. It could be adrenal issues. It could be gut issues. It could be nutrient issues. It could be mitochondrial issues. So all of these things are potential stressors that could be driving that problem.

Evan Brand: I’d say number one is probably thyroid issues. Wouldn’t you suspect because so many people we talk with they have adrenal issues with them on top of that there is a thyroid problem. Like maybe elevated reverse T3, whether you’ve got that blank bullet going on or they just got a low free T3 or like you and I’ve chatted about with adrenals, you’ve got the conversion process that happens where you take the inactive T4 hormone, you convert that to active T3.That conversion process gets messed up if you’ve got chronic stress. And chronic stress as you mentioned, could be gut infections, it could be emotional stress, could be chemical, heavy metals. It could be circadian rhythm stress if you’re working third shift, for example. That could be enough to change this whole cascade. Wouldn’t you say?

Dr. Justin Marchegiani: Oh, yeah. Hundred percent. I mean, again, all of those things can be intimately connected. The first we look at is thyroid because thyroid hormone has a major effect on our metabolism. And our metabolism is the sum of all chemical reactions in the body. And our metabolism is pH driven, right? So if our pH becomes too alkaline or too acidic, like you know blood pH, which exists in a very fine-tune range, right around 7.35+ or -1/10 of point there. And if that pH shifts up or down, that can affect how all of our enzymes in our bodywork. So that can affect temperature and there’s things like—uh like a diabetic coma, right? Where blood sugar can go to he— or too low typically. If someone’s type I dependent and they don’t have insulin, they don’t get sugar into their cell, which can create ketoacidosis. And that can really, really drop that pH and that put you into a coma. So our pH is very driven and has a major effect on our metabolism, so, totally.

Evan Brand: So let’s hit on—let’s hit on the thyroid peace. Now autoimmunity is something we talk about so much. Would you say a common symptom of someone with Hashimoto’s, for example, could be low body temperature or possibly even a fluctuating. Maybe their low body temperature if they’re a bit underperforming but then couldn’t they just bounce right back and get actually hot if they bump into hyperthyroid. If they’re in the Hashimoto’s state, and things are still fluctuating.

Dr. Justin Marchegiani:  Yeah. So, if you’re having Hashimoto’s and your immune systems constantly attacking your thyroid, your thyroid hormone can spill.

Evan Brand: Right.

Dr. Justin Marchegiani: Coz every time it’s attacked, hormone spills out. Eventually those follicles run dry and you’re not gonna quite have that hyper kind of symptoms. So in an acute attack, hyper symptoms may be increased temperature are common, right? You can have like PVC’s periventricular contractions. Uh—you can have, you know, kinda this—kinda heart palpitations. Your heart’s kinda beating erratic and hard, uh—anxiety, night sweats, irritability. These are all hyper thyroid symptoms. You feel warming, right? You feel excessive warmth or temperature. But then, in a chronic state, that will eventually lead to a hypothyroid kind of environment, where your body temperature just gets very low.

Evan Brand: So someone has had Hashimoto’s for quite some time, let’s say there’s been a pretty significant tissue destruction, you would say someone will not end up being hyper long-term with Hashimoto’s. It’d probably be hypo long-term.

Dr. Justin Marchegiani: Yeah. I mean you can—hyper feels very similar. Hyperthyroid Grave’s feels very similar to a hypothyroid autoimmune attack. The difference is with hyper, typically, there’s a specific antibodies or immunoglobulin compounds that come back. So with Grave’s, you’re seeing TSI immunoglobulins or you’re seeing thyroid TSH receptor site antibodies. So that’s what’s typically common in Grave’s. And when those things are high, it’s accelerating the thyroid hormone to produce excessive amounts of thyroid hormone. So there’s like a production stimulation where with the autoimmune attack, from like thyroglobulin antibodies or TPO antibodies is it’s more the spilling of a thyroid hormone out of the thyroid. It’s spilling out where the antibody attack from Grave’s, it’s stimulating the thyroid to produce more.

Evan Brand: Exactly.

Dr. Justin Marchegiani: With Hashimoto’s, you’re not getting the stimulation. You’re more or less getting that spilling effect, which eventually, you know, will run dry.

Evan Brand: Got it. Got it.  Okay. So we hit the autoimmune piece. What else would go on thyroid-wise that will be an issue with temperature regulation?

Dr. Justin Marchegiani:  Well, again, there’s also certain nutrients that have a major effect on thyroid uh—conversions. So we know things like selenium are super important for thyroid conversion. So someone may have decent thyroid levels from a T4 perspective, uh— but they may not have that activation, right? They may not have that conversion uhm— that’s so important.

Evan Brand: So could it just be the lack of trace nutrients, trace mineral selenium, zinc— things like that activators.

Dr. Justin Marchegiani:  So here, we are live on Facebook now, too with the low body temperature podcast. So getting back onto our common thread. Yeah, micronutrients like selenium are gonna be important for thyroid conversion. It’s a five—the enzyme that converts T4 to T3 inactive thyroid hormone to active thyroid hormone is a 5 deiodinase enzyme. It’s also important with glutathione and detoxification. So, yeah, that’s totally uh— important micronutrient that will affect thyroid activations. So when we look at thyroid function, we’re looking at are there blood sugar fluctuations? Are you eating grains or foods that are gonna cause that thyroid antibody attack that could cause the hormones to spill out and eventually deplete the hormones? Your thyroid follicles carry about four months of thyroid hormone. So again, if you have a chronic Hashimoto attack, where the thyroid hormone’s spilling out faster than you can synthesize and make more, then you’re going to definitely get to that depletion state where you’re gonna go hypo from a temperature standpoint. You’re gonna go almost hypothermic. That temperature will drop below that 97.8 – 98.2 armpit temperature wise or 98.2 to 98.6 and I’ll put a handout down below to my uh— metabolic temperature handout. So people can actually track their temperatures and it’s basically a graph of three different lines. And then the top brackets where you want your temperature to be through which ranges 97.8 – 98.6 We want to be checking off daily that your temps are in this bracket not the bottom or the very bottom.

Evan Brand: Got it. Okay. So what else? Should we talk about the nutrients next?

Dr. Justin Marchegiani: Should we talk about the nutrients, right? Vitamin A, we talked about uh— zinc, copper, selenium, magnesium very important nutrients for thyroid conversion. Now if you’re eating a whole food diet, you’re gonna be typically pretty good. If you’re having enough HCl and enzymes, you’re gonna be good as well because we need those type of compounds to be able to ionize the minerals. So it’s the diet component. It’s making sure we have the ability to break down the foods in our diet that are nutrient dense. Uhm— number three is making sure our stress response is okay because stress hormones will affect thyroid conversion. Cortisol being hyper— very high— will affect thyroid T4 to T3 conversion that inactive to active thyroid hormone. Also, if cortisol is too lo from chronic stress. So there’s this, kinda Goldilocks effect that we see here with thyroid hormone kinda need it to be not too high, but not too low to have optimal conversion. Does that makes sense?

Evan Brand: Yeah. It does. Well said. Let me mention about the gut, too, coz you just hit on the fact that you’ve got to have absorption. So even if the diet’s good, which many people listening to us, they probably already dialed in like a Paleo template but they could still have this symptom. You may want to check for infections. Coz like Justin and I talk about almost every week at some level, there could be an H. pylori, bacteria, yeast, fungus, something going on in the gut that’s stealing your nutrients or preventing you from optimally digesting. And then that issue is compounded, if you’ve been taking any type of anti-acid where acid blocking medication something simple as Tom’s or something more strong like a prior was it Prilosec or Zantac.

Dr. Justin Marchegiani: Yeah. So, yeah. Totally.

Evan Brand: Keep that in mind. If you’re looking at your medication list and that includes acid blockers and you have cold body temperatures, it’s probably cause you’re not digesting your foods therefore the thyroid is not getting fed the nutrients it needs.

Dr. Justin Marchegiani:  Totally. And also a lot of medications could affect your mitochondria. Just Google antibiotics and mitochondrial function, you’ll find that antibiotics can negatively impact mitochondrial function. And you’ll also find that other medications can impact the mitochondria. And the mitochondria is like the little powerhouse of your cell where it generates a lot of ATP, which is that currency of energy in which your body runs. So that’s really important and also an important nutrient call carnitine really helps that mitochondria utilize fat for energy, generate ATP out of that good fat, you know, it’s called uh—beta oxidation where you’re generating energy from fat. And carnitine is an important nutrient primarily made from methionine and lysine. Now, I did a video call why vegan and vegetarian diets can make you fat? Now—no—don’t make you fat. But you know, why they the can—meaning it’s not a hundred percent. But if you’re insulin resistant and you’re doing it the wrong way, where you’re emphasizing maybe too much carbohydrates, not enough protein and more gut irritating foods, yeah, it can definitely predispose people that have an inflamed guts and work more on the insulin resistance side to gain weight. And one of the big things is that when you eat certain animal rich amino acids, there are some plant ones as well, you activate the cells in the brain that are called—hold on, one __my notes—uh—tenocytes. And these tenocytes are receptor sites in the brain in the third ventricle area of the brain. And there’s a direct blood flow between them and the hypothalamus. These tenocytes, one, they sense satiety but the big thing that senses satiety for them is arginine and lysine which are really high in animal-based foods. So these amino acids really get that sense of satiation so that means you’re one, gonna have appetite regulation. Coz when you actually start feeling full, you tend to not eat all the crap, right?

Evan Brand: Yup.

Dr. Justin Marchegiani: So the more you can keep your cravings in check, the more you eat healthier foods because you got control over your biochemistry. You’re not reacting. You’re acting based on what you know you need to be healthy. But those amino acids are primarily gonna be higher in animal-based foods especially lysine as well.

Evan Brand: Yeah. Well said.  So in a roundabout way, if you are a vegetarian or a vegan and you’ve got low body temperature, it could just be something as simple as a carnitine deficiency. I mean you could probably get a little bit in beans maybe—

Dr. Justin Marchegiani:  A little bit in beans, a little bit in almonds, a little bit in plums and avocados, for sure.

Evan Brand: But even then, once we talked like—we talked all the time, digestion of those foods is probably not very good and the concentration of those is gonna be much less as opposed to a grass-fed beef.

Dr. Justin Marchegiani: Yeah. In my video, I talked about, you know, if you are a smart vegan where you’re not emphasizing a lot of the grains, you’re doing safer starches, you’re getting lots of fats from avocado, olive oil, coconut oil, you’re supplementing DHEA in the form of algae, right? And if you’re getting B12 uh—supplementation and you’re getting a good multi- in there and you’re getting lots of— you’re getting some protein supplementation in there, maybe from pea or hemp, right? You may be okay on a vegan-vegetarian diet, but it’s just— it’s still less than optimal just because of the fact that you gotta go through such extreme lengths to get high-quality protein sources without all the carbohydrate. Coz vegetarian-vegan diet’s typically are packed with 60 to 80% carbohydrates for that 20 to 25% of protein you get.

Evan Brand: Yup.  Well said. You hit on the mitochondria, too. We should take  that a bit further and talk about more toxins. You hit on antibiotics, some mitochondrial issues there. Makes perfect sense. We work with people all the time where they say, “Oh Justin or Evan, as soon as I took a round of antibiotics, all of a sudden things went bad.” And it could be temperature –temperature issues, it could be sleep problems, it could be gut issues, digestive problems. And so also with mitochondrial issues, we’ve got toxins. So if you’re not using 100% organic, that’s an issue because glyphosate and these other pesticides and herbicides, fungicides and insecticides— they all compound with each other. So it’s not that one chemical by itself will kill you, but if you get a little bit of glyphosate from your non-organic berries, you combine that with a little bit of conventional vegetables coz you did a salad at a restaurant, you combine that with in antibiotics that you’re getting from meat. If it’s not labeled “no antibiotics” you stock all those upon each other, you’ve got some bad mitochondrial problems here that you need to fix. And we can measure the—

Dr. Justin Marchegiani: Yeah. The enzymes that are needed to help move those gears that  kinda crank around that mitochondrial Krebs cycle and then flow in so the beta oxidation process. Uhm— you need certain nutrients. You need B vitamins, you need magnesium, you need zinc, the healthy levels of amino acids. You also don’t need all the toxins— the aluminum, the pesticides, the glyphosate. So those things can kinda gunk up the gears of that metabolic machinery. So it’s not only what those gears need to keep it lubricated, but what it is we don’t need to put in that will prevent those gears moving. So it’s a combination of avoiding certain things, right? And again, the medications are a double-edged sword. I’m not saying don’t use them. I’m saying just really make sure they’re— they are prescribed specifically for what you need. And it’s the last case kind of thing with antibiotics. We really want to go to herbs and botanical nutrients over antibiotics. They may have a time or place, but we want to use it only when we’ve exhausted other options.

Evan Brand: Yeah. Well said. And you and I were talking off air, we can quantify a lot of this stuff, too. So you’re talking about measuring your temperature. We can quantify what’s going on in the gut, right? We can test the gut, we can test the thyroid with—with blood using functional reference ranges and using functional numbers that conventional doctors don’t use. They’re only going to detect disease. We’re going to detect the issues before disease occurs. We’re gonna look into the gut so we could test you for infections. We could test the adrenals, look at your free cortisol rhythm so the uh— HPA axis, the hypothalamus, pituitary adrenal axis, you hear us talk about, you know, that is a factor in all of this. If your brain is not connecting the signal to the adrenals and adrenal to the thyroid, that whole system gets often chronic stress. And it’s up to us to figure out when we talk about stress what’s in that bucket. Is it just your job, your bad boss, your relationship, the divorce you’re going through? Is it that stuff only or is that stuff plus chemicals in the diet, plus nutrient deficiencies, plus infections, plus not having enough quality meat in the diet.  You see how these things can all add up.

Dr. Justin Marchegiani: Totally. And just to kinda look at the thyroid component again, there’s dysregulation up top where the TSH is either high extreme, higher extreme, low. Now it can be extremely low because you’re on thyroid hormone and the body needs more thyroid hormone. The body is sense— sensing more thyroid hormone in the brain, but there’s less than the actual tissues. So that you’re keeping the thyroid hormone higher, but that’s keeping the TSH low. That’s step one. The TSH may be low because of HPAT access dysregulation. That hypothalamus pituitary and that adrenal thyroid axis. There’s some kinda short-circuits happening in there because of the stress— the emotional stress, because of the physical stress, because of the chemical stressors. And we have to address those while we support the nutrients to get this hardwire back on track. We can also have low T4 levels. Coz if T4 is low, we’re gonna have low T3 over here. So we got to make sure the nutrients for T4 in there like I mentioned before the vitamin A, the zinc , the copper, magnesium, selenium, uhm— amino acids, tyrosine and potentially iodine. As long as we know that there’s not uh— autoimmune attack that’s the lease active going on. And then number three, after that, we let see how the T4 to T3 conversion is. If T4 is good, how does T3 conversion look? Is it this big drop off? Or also is there a very high amount of reverse T3 because of that stress? All those can make a big difference. And then one person ask here—James asks, “Well, is hypothyroid and hyperthyroid hypo and hyper kind of the same for treatment?” Yes and no. With hyperthyroid from a TSI thyroid stimulating immunoglobulin or TSH receptor antibody attack, we’re more concerned about coz it tends to be more chronically high which can increase the chance of a thyroid storm and then potentially a stroke. So we take that very seriously. We refer that patient out to their medical doctor uh—for monitoring. We don’t want—we wanna make sure there’s not a stroke going on. But typically, the treatment will be, you know, PTU. Uhm—basically  uh—propylthiouracil or methimazole. Things to basically block iodine uptake to make thyroid hormone. Or though— you know, typically, go to a thyroid radioactive thyroid kind of ablation or even a thyroidectomy. I’ve had patients where we’ve been able to avoid those because we give nutrients to help modulate the thyroid response and modulate the autoimmune response like carnitine, like blue flag, like lemon balm, melissa uhm—into certain adaptogens. They could also help kinda dampen that response. There are some protocols that even show higher amounts of iodine can block that sodium uhm— iodine’s import that transfers iodine into the thyroid. So there’s a couple of different protocols you can use to help. And of course, all of the diet and lifestyle things are the same. But we take the Grave’s autoimmune attack a little bit more seriously just because of the repercussions of it not being treated appropriately, what will happen, we really want to sidestep those.

Evan Brand: Yup. Well said. So get the TPO antibodies checked. Get your eTG antibodies checked, you talk about the TSI. Now, have you seen where TPO TG would be high at the same time as TSI? Where it’s gonna look like Hashimoto’s and Grave’s at the same time?

Dr. Justin Marchegiani: It could. I’ve seen it before.  Yeah. It definitely can. So get—we’re  gonna really get patients on an autoimmune protocol to help lower any autoimmune attack from the food, from the gluten, from the leaky gut. And we’ll also work on blood sugar stability coz high and low blood sugar fluctuations have a major effect on the immune system.

Evan Brand: Yup.

Dr. Justin Marchegiani:  Now another person asked here, the reason why you know I’m such a huge fan of how we do our podcast is coz it’s literally on the go and we’re infusing questions from people on YouTube here right into the conversations. So it’s like—remember those books you read when you’re like a kid and you read it and it’s like, “Oh, if you want the character to do this, turn to this page. If you want the character to do this, turn to this page.”  You can totally change how the book goes.

Evan Brand: Yup.

Dr. Justin Marchegiani: Well, it’s kind how our podcast are. So interjecting here uhm—, Gerald asked, “What about T3? How does T3 work?”  Well number one, T3 can just help support low T3 levels. And if there’s some kind of conversion issue, that can kinda biased time to fix the conversion aspect, number one. Number two, giving that T3 in the Wilson protocol uhm— that can have some effect on clearing out the receptor sites. So that now the T3 works better and binds better uhm— in the future. You can do that by starting low and then tapering up, holding it and then tapering it back down. In the Wilson protocol, Dr. Dennis Wilson does that with time-released T3. But we do a glandular’s in it. That can still be helpful as well. We’re using that as a way of clearing out the receptor site but were also not, you know, thinking that that’s gonna be the only issue. We’re also banking that there’s other things that we’re gonna be fixing that will allow it to be a long-term solution, right?

Evan Brand: Got it. So you’re saying the thyroid glandular’s can be used for low—a low  T3 situation.  That’s the fix that’s going to get you better enough to keep moving the needle in other departments.

Dr. Justin Marchegiani: Correct. Like in my line, we have Thyro Balance which is a—a really glandular uhm—nutrient thyroid support from a glandular perspective. And then we have that we have Thyro Replete which is nutrients for the conversion. So there’s some herbs that help with conversion like coleus forskohlii and ginseng and then we have the nutrients for conversion that I mentioned—the vitamin A, magnesium, copper, zincs, selenium—all of those—and tyrosine’s. We wanna make sure all those are in there. Uhm so we hit it from all angles. I mean if we knew exactly what that missing like nutrient component was, we could hit it more practically. But it’s too difficult to do that.

Evan Brand: Right.

Dr. Justin Marchegiani: You’re better off using multiple methods to hit it. That way the patient can get better faster.

Evan Brand: Agreed. And you mention the adaptogens. I’m so glad you did. We use those all the time. I take them every day in some shape or form, whether it’s ashwaganda, holy basil, shoshandra. There are so many options and people ask, “Well, can I just take a bunch of adaptogens and fix myself?” Uhm— it doesn’t work like that. You just want to use them as one piece of your toolbox. You still want to be getting to the root cause. So adaptogens are life-changing but if there’s root causes, you can take all the adaptogens in the world and it won’t fix you.

Dr. Justin Marchegiani: I’m gonna take my ashwaganda right now—

Evan Brand: Perfect.

Dr. Justin Marchegiani: A little bit of immune support. But I mean, like yeah, if you’re doing okay and you’re like, “Hey, Dr. J and Evan talked about some ashwaganda and some of these nutrients. I want to try it out.” Fine, go ahead.  But if you’re actively having issues that are you know, the symptoms that we mention here whether it’s on the hyper or hypo side, you really want to get someone on board to help guide you because it’s never just one magic bullet. It is—it’s a whole bunch of things that we’re doing together. And the more chronic it is, the more you have a you know, that momentum working against you. You got overcome that inertia to stop that— that snowball effect and start pushing it back uphill. So, yeah, if you’re in pretty good shape, fine you know just try some of these things. But if you’re in not so good shape, you want to reach out, for sure.

Evan Brand: Yep. Cool. Oh, we got time for one more question. Uh James said, “It’s not a thyroid question.” He’s taking an antibiotic for root canal this week. “Will this affect the result of organic acids test and stool test if he collects the samples while antibiotics are still in the system?”

Dr. Justin Marchegiani: I mean if we’re doing some of the genetic base testing, it shouldn’t have an effect on it. If we’re doing a stool base to antigen-based testing, then it would.

Evan Brand: Right.

Dr. Justin Marchegiani: So you should be okay but we’re doing the G.I. map which is you know, what my go-to is. It should be okay according to the lab. I try to avoid it— doing it. So I would say in a perfect world, if it’s not gonna delay your treatment, I would say get to the antibiotics give it like a day or two to let it wash out and then do it. But if uhm— timing doesn’t work out, just do it, get done.

Evan Brand: I would also look at Mercola root canals and read about those. I mean maybe you’re too far down the rabbit hole and you can’t avoid the root canal. But you know there are some other options you may have available if you’ve got a good biological Dennis maybe will sit down with you and say, “Okay, root canal’s option A but maybe there’s a option B C you could look at too because we’ve had a lot of people to come to us with infected root canals and maybe Jessica can speak on this a bit. But I’ve seen it as a big needle mover for people.

Dr. Justin Marchegiani: Yeah. There’s a book by Ramiel Nagel that talks all about root canals. It is highly recommended. You take a look at it. Uh— fat-soluble nutrients, vitamin A, vitamin K are very helpful. Uh—oil pulling that kinda help extract any toxins that may be in there and you don’t want a root canal you want to get the tooth pulled out. Uhm— you want to get an implant put in using biologically appropriate material. You don’t want the gangrenous tissue still in the system without the blood flow. And the immune response to be able to get it is just a harboring place for a whole bunch of bacteria and viruses to hang out.

Evan Brand: Right. Yeah. Well said. So James, look into that. Maybe it’s not too late. Uh—hopefully, you’ve got some other options you can pursue it’d be much— much safer and much healthier in the long term. That way, you don’t have a hidden dental infection. There’s a guy named, Simon Yu that you and I should reach out and interview. He’s over in St. Louis he talks a lot about hidden dental infections. I think that’d be a good show.

Dr. Justin Marchegiani: Okay. Absolutely. Hundred percent. So couple of things we wanna talk about. Oh, also carbohydrate, I think is important. Again, my bias is towards a lower carbohydrate template—Paleo template. And again, I hate the word “diet” because it assumes something is temporary and it assumes that it is fixed; where a template gives us flexibility and modification and may change day to day. It may change uh—meal to meal. I tend to be very lower carbohydrate my first two meals of the day and then after that, I may increase in carbohydrate at nights uhm—you know a bit of the starchy based. So I’m very strict during the day. It’s high-quality. It’s— set—it’s 60 to 70% fats, the only carbohydrates are vegetables and then good proteins and then I go higher at night. On the carbohydrates side, maybe a little bit of sweet potatoes and some butter and cinnamon or maybe I have a—some dark chocolate or have couple more berries than I normally would. So there’s that component. So I always go lower carbohydrate to start because so many people are insulin resistant just because of the fact that we eat too much carbohydrate and were inflamed. So I always go lower carbohydrate to start and then typically, patient will do be better and will feel better because insulin resistance can affect T4 to T3 thyroid conversion, which can cause lower temperature. Now, in the double edge side of the fence, if people go too low insulin, they may also get poor thyroid conversion as well. So just like I mentioned cortisol has a major effect on thyroid conversion. Well, guess what? Insulin has a major effect on thyroid conversion. Type I diabetics— guess what? With low insulin levels coz of the autoimmune attack to the beta cells of the pancreas, they have low body temperature. So if you go too low carbohydrate, and this is for certain individuals not everyone, I know people are gonna be like, “But I’m low carbohydrate and I felt great and it reverse my low temperature.” I get it. Again, there are exceptions to every rule. There are tall Chinese people that play basketball even though they are more shorter in the population. There are exceptions to everything, okay? We got to get that in. So yes, there are some people that a low carbohydrate diet, the majority I would say would help partly because our consumption of refined carbohydrate and sugar is higher, but there are some people when they’re chronically load, they may increase that carbohydrate just a bit. And that ups the insulin a little bit which then helps that thyroid conversion. They’re like, “ Dude, my hair started to grow back better, my temperature’s better, my energy is better.” Boom! You at least now figure it out for you. So exceptions to every rule, figure it out. And uhm—if you feel great going low-carb, great, keep it there, hang out. But if you start getting some of those hypo temperature symptoms, then we’ll just ratcheted up a little bit.  And I primarily ratcheted up starting at night.

Evan Brand: Yup.

Dr. Justin Marchegiani: They’ll still get the benefit of keeping it lower carb during the day.

Evan Brand: Well said. I mean that’s me in a nutshell. I went very, very, very low-carb ketogenic, I guarantee. I was probably ketogenic most of the time and then I started to get cold and so I added in some starch with dinner and all of a sudden my body temperature’s perfect now. I feel good. So uh—if I go too low-carb again, it may come back or if there’s a huge piece of stress on my plate, the low body temperature may come back. But for now, I’ve been able to reverse this and been able to clear out all the infections with your help in terms of protocol a couple of years ago getting rid of all my gut bugs, plus supporting adrenals, getting the diet dialed in, getting my sleep improved, blacking out my room. All of those things are still important. So I hope this has been helpful. I gotta run. You’ve gotta run, too. Uhm—or are there any last questions that we could answer? I closed out the chat window. Uh there’s just one thing I want to say is it’s not about being higher carb or lower carb, have a –have a foundational template which you— which you go back to and then you can customize it. And then if you increase carbs, you can still get some of the benefits by having that first 20 hours of your meals relatively lower carb, higher fat, moderate protein and those last four hours you pop up a little bit and so you can still get some of those benefits. If you’re like, “Oh, I feel better with higher carbs.” You can still get the benefits of the first 20 hours of your day kinda in that ketogenic state and then pop up the carbohydrates later. So it’s not an either or thing. We can kinda straddle the fence but we want to customize it. I don’t give a crap if—if low-carb is your missing link and being low-carb all the time helps you, that’s what we’re gonna do. If being low-carb and a little more high carbohydrate helps you out, I don’t care. I’m all about the results and not about what tool I have to use to get the job done.

Evan Brand: Yup. Well said. For me that looks like the breakfast like a pastured sausage, maybe a handful of macadamias, maybe a handful of organic blueberries. Lunch—I  probably do some leftover steak and veggies like a big thing of broccoli with some butter. Dinner— that’s when I may do some type of pastured meat, a little bit of some veggies and then starch, so it could be a medium-size baked sweet potato, butter, cinnamon. That’s all it takes and I feel good. So just to kind of give people an idea what is that look like. That’s what it looks like.

Dr. Justin Marchegiani: Totally. That’s great. And a couple of questions here. Uh— Stephanie talks about menopausal women with lower estrogen and a low estradiol vaginal tablets. Well, this is interesting because typically low estrogen can cause hot flashes. And why does that cause hot flashes? Because typically the FSH and the LH starts to rise in the pituitary which is that signaling hormone trying to yell to the ovaries to make more progesterone and estrogen. So when LH and FSH primarily FSH goes high, that can create some vasodilation effects and create the hot flashes. So by giving a little bit of thyroid—giving a little bit of uhm— female hormone support, we can drop down that FSH then we can also modulate the receptor sites with some herbs as well to help with how flashes. Whether we use maca, or  we use dong quia, or black cohosh or raspberry root, or shepherds purse. There’s different nutrients or herbs we can do to help modulate that. So again, you could still have hypo, low thyroid issues, but have menopausal issues because of the low estrogens, which could drive the hot flashes up. So it’s kind of a conundrum. The hot flashes may—may overshadow this low thyroid thing over here. So as we get the female hormones fixed, you may notice the low thyroid comes back later on because it’s just not a secondary issue and the primary issue is the menopause. Once that’s ruled out, now this one comes to the surface.

Evan Brand: Got it. Well said.  We should probably do a whole show just on low estrogen if we haven’t.

Dr. Justin Marchegiani: I think that’d be great. I mean, I see estrogen dominance is a big problem.

Evan Brand: Right.

Dr. Justin Marchegiani: Where estrogen –the ratio of estrogen is higher than progesterone, right? So progesterone should be like this 25 to 125 times more than estrogen. But if that ratio starts to creep up where estrogen gets higher, that’s estrogen dominance. The problem is a lot of people, though, where that ratio—they’re estrogen dominant, progesterone’s slow but estrogen is also low. So they get this estrogen dominant, but also low estrogen sums at the same time. So it’s kinda like this conundrum. It’s like this little tug of war that’s happening there.

Evan Brand: Wow. Put it on this to do list. It sounds like it’s gonna be a fun one for us to dive into more. And I’ve probably got some stuff to learn from you on that topic as well.

Dr. Justin Marchegiani: I think it’s great. Well any last questions, comments, or concerns, Evan?

Evan Brand: No. I think this has been good. People, you got to get the testing run because if you don’t test, you’ve guessed. So if you’re trying to figure this out on your own, even if you’re not working with Justin or myself, then get the test run. Find a functional medicine practitioner they can take care of you. We are accepting new clients, so if you do need help, feel free to reach out justin health.com evanbrand.com We run these labs on all of our clients because it’s the foundation. We’ve got to have the data. We’ve gotta have the puzzle pieces on the table; otherwise, you can’t move the needle. We could throw a bunch of random stuff at you might help, can’t hurt, but we want to get you better. There’s a systemic process that we do step by step by step to take you through this. So happy to help. Reach out if you got questions and thanks for tuning.

Dr. Justin Marchegiani: Oh! One last thing, man. I forgot to add.  This is so important. Low calories.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Just not eating enough calories will cause low body temperature. It’s shown to cause a low level T3. Now this is important because if your diet is 25% crap Ola and let’s say you’re eating 2000 calories a day and then we switch you over— we switch you over to a uh— autoimmune kinda Paleo template, but you’re only able to—to—to switch over 75% of your diet because you don’t—you don’t have enough you—you can’t replace all the crap that you’re eating with the good stuff, right?

Evan Brand: Right.

Dr. Justin Marchegiani: Because if you’re eating a whole bunch of crappy carbohydrates and stuff and then you replace it with a whole bunch of really good vegetables or lower sugar foods, well guess what? You’re probably didn’t replace the calorie amount either. So now you got this 25% calorie deficiency. So now instead of having 2000 calories, right? Now you’re having 1500 calories and maybe metabolically you need 2000 calories. Now you’re 500 calories in the hole which means your 500 calories deficient of various nutrients. So now your metabolism goes low coz there’s less fuel. That’s important. I see a lot. So you gotta  work with someone that really can make sure you’re exchanging the foods and you’re getting enough calories as well. Coz calories equal nutrition. if you’re eating real foods.

Evan Brand: I’m glad you mentioned that. That’s such a simple but common issue. If you’re going AIP, you are going Paleo, you’re eating real foods, you could have an entire plate full of broccoli and it may only be 50 calories.

Dr. Justin Marchegiani: Exactly.

Evan Brand: Yeah. Dude, great job. Way to kill it.

Dr. Justin Marchegiani: And of course, the infections like you mentioned can really suck down the energy. Of course, acute infection, you know, you’re causing a fever, right? Because the immune system’s trying to up regulate itself because a lot of the bacteria and crap there uhm—they’re like—they’re mesophilic. They—they thrive in a medium temperature. So when you go a little bit higher, you can actually kill them off with a higher temperature. But these chronic bugs can really deplete the energy the body and create this kinda lower temperatures as well. For sure.

Evan Brand: Yeah. And I went—I went to low-calorie for a period of time, not intentionally, not on purpose. It just happened. I was eating meats, I was eating veggies and  I track my calories for a few days and I was eating m—and my activity level  and all that. I was probably 4 to 600 calories deficient. So just added in an extra tablespoon of butter here and there, half of an avocado here and there, handful of nuts and seeds. And I was right back up to where I needed to be.

Dr. Justin Marchegiani: Like here’s a seesaw right?

Evan Brand: Yup.

Dr. Justin Marchegiani: So if like carbohydrate is here, if carbs go lower— this is fat over here. The fats have to go up.

Evan Brand: Yup.

Dr. Justin Marchegiani: If you keep the fats here, you keep the fats on—on this side low, and drop the carbohydrates, that’s where the problem happens. The fats also have to go up. That’s the biggest issue. Proteins typically stay in the middle. Typically, proteins only go up if you’re doing a whole bunch of protein powders because proteins and fats are intimately connected. Uh so if you’re eating real whole foods, you know, it’s hard to get just proteins in whole foods, unless you’re doing maybe like venison or rabbit or like boneless chicken breast. But if you’re eating full fat foods, you’re gonna get fat. And then if you’re adding fats to your vegetables, you’re gonna get extra fat without the protein there as well.

Evan Brand: Yeah.

Dr. Justin Marchegiani: So keep that at the back of your head.

Evan Brand: Perfect.

Dr. Justin Marchegiani: Anyone listening here, give us comments below. Give us some shares. Give us some likes. We want to hear thoughts in the comment section. If you’re listening to us on iTunes, that’s great. Click below and subscribe to our YouTube channel. You can see Evan and I’s mugs going back and forth in our little combos here. And then you can give us some comments below here on YouTube. We love the see the feedback. And Evan, hey man, you have a great day. We’ll talk soon.

Evan Brand: Take care.

Dr. Justin Marchegiani: Take care. Bye.

Evan Brand: Bye.

 


 

References:

justinhealth.com

evanbrand.com

https://justinhealth.com/products/thyro-balance

https://justinhealth.com/products/thyro-replete/

http://www.curetoothdecay.com/

Foundational Nutrients for Optimal Health – Dr. Justin Live Podcast # 155

Dr. Justin Marchegiani and Evan Brand dive into the topic of nutrients and their importance to our bodies. Listen to this podcast and learn how B vitamins, Magnesium, Vitamin C & D, Selenium, Zinc and Omegas contribute to achieving a healthy body. Understand how these vitamins and minerals support different bodily functions and gain an understanding on how their deficiencies affect our health and cause unfavorable symptoms.

Explore other topics related to nutrients as they answer questions about leaky gut, H.pylori and some blood pressure medications which contribute to nutritional deficiency. Know some of the best sources of supplements and product recommendations which have been proven effective based on their practice and professional experience.

In this episode, we cover:

09:00   B vitamins

11:25   Minerals + Magnesium

28:15   Vitamin C, Selenium

31:18   Zinc

33:10   Omegas

36:26   Vitamin D

Just In Health iTunes

Just In Health Youtube Channel

 


Dr. Justin Marchegiani: And we’re back. It’s Dr. J here with Evan Brand, my man, how are we doing today?

Evan Brand: A happy Monday. If you’re watching in the future I guess the day doesn’t matter but for us it does.

Dr. Justin Marchegiani: I had a great weekend, man. I was doing a little waterskiing action today. It was phenomenal—actually yesterday, I’m sorry. Great, great day and back in the saddle for an awesome Monday. Got some patients coming up right after our live podcast. How about yourself man? Anything good happening for you?

Evan Brand: Uh—Actually, Yeah. I’m going to create a pretty cool piece of content as soon as you and I get off the call together, I’m gonna go eat some lunch and a I’m gonna drive about an hour away to a local hemp farm where there’s a guy who has a Kentucky hemp oil company that I’ve been seeing his products everywhere. His son was having a major seizure disorder. His son was having hundreds of seizures within a week. And he started to use cannabis extracts to help his son and now his son has not had seizures for years— several years. And so this guy he moved from Northern California where he was growing medical cannabis and now he’s just growing hemp in Kentucky and so I’m driving to the farm. I’ll probably end up doing a podcast with him coz I don’t think it’s gonna be easy to do it in the field, but I’m gonna  try to take my camera and puts— maybe a 45 minute little video together, try to interview him, get a little bit his story and share his products coz I’ve been using the CBD with my clients. And as you and I talk about with inflammation and the anti-anxiety benefits, you can pretty much use it with anyone. And it’s going to help regardless of the case whether it’s like Lyme or Hashimoto’s or H. pylori. Whatever we’re dealing with our clients, I mean we can pretty much use CBD across the board and we might notice some beneficial changes and it’s definitely not gonna hurt somebody. So looking forward to going to meet that guy. And stay tuned because I have a video probably the next week that’s gonna be published on it.

Dr. Justin Marchegiani: Love it. Yeah. I think CBD has some really good benefits. I use on handful of patients for pain issues, for sleep issues, uh—for anxiety, just from immune balance. And I do fine. It’s— it’s very good. CBD or Cannabis Diol is the non-psychoactive component of marijuana or hamper cannabis, if you will. THC Tetrahydro Cannabis that’s gonna be the part of the marijuana that gets you high and kinda gives you the munchies. So you get some of those benefits with the CBD without the, you know, the higher the munchies afterwards. And I’ve seen it work very well with seizures like you mentioned, very well with autoimmune and pain stuff. I mean it can be very therapeutic. I don’t think it fixes the root cause but I do think it’s very, very therapeutic. It can help.

Evan Brand: Right. Well said. Yeah. Definitely not gonna fix the root cause but I’ve had some people too that are in California, other states where they can even get recreational cannabis and I tell people go for it if they asked me because if they’re doing a tincture or they’re doing a spray or sublingual, they’re not having to smoke, they’re not having to use a vaporizer if they just don’t want to get the high, there’s— there’s tons of different options where you can do a high CBD. And a very tiny amount of THC where people can help fix their sleep. I had a __ in California she’s had chronic pain. She’s had Lyme forever. She said if she does CBD by itself, does pretty much nothing; but when she adds just like a milligram, so do say, 10 to 50 mg CBD, 1 mg THC, all the sudden the synergistic effect happens and the pain goes away.

Dr. Justin Marchegiani: Yeah. They can be very helpful. It’s a good tool in your functional medicine uh— pockets, so to speak.

Evan Brand: Yup. Hey, Robert, thanks for joining us. James, thanks for rejoining us. Our topic, well, we figure we’ll do a Q&A but our topic initially is about foundational nutrients kind of what the things that are actually worth your time and money because Justin and I were so many people come to us after they’ve been to other functional medicine practitioners. And we’ve got a kind of clean up the mess and there’s like 20 or 30 or 40 supplements that people are taking. And we like to try to whittle that down to just some of the foundations. And some things people are taking might help and can’t hurt, but if you’re spending a thousand bucks or something crazy amount on supplements, we really want to give you the stuff that just gonna move the needle coz why take something if it’s not gonna do stuff for you.

Dr. Justin Marchegiani: 100%. And again, kinda foundation before we go in is a Paleo template to start. And again, that’s macronutrient agnostic. It could be high-carb, low-carb, high-fat, moderate fat, high-protein, moderate protein, right? So we’re just focusing on the anti-inflammatory, nutrient dense, low toxin foods. That’s number one. And then from there, the next step above that is making sure we have the lifestyle stressors in order: sleep, hydration, uh—not eating when we’re really stressed, that’s number two. And number three is actually making sure we can digest the foods that we eat. We eat a really good diet but we can’t break it down. That’s the equivalent of going to the grocery store and leaving that food out on the counter, not putting it in the fridge for a week or two. It’s gonna rot. So the next step above that is HCL and enzymes and digestive nutrients so we can break those really good foods down. That’s our foundation. And once we have that, that’s where I think some of the nutrients come in. So with my patients, all of them, they’re on all either the Multi Nutrients Supreme or Multi support pack which has the extra, kinda stress handling nutrients that are gonna be in there which are gonna consist of high-quality B vitamins that are methylated or activated like P5P uhm—of course, like your B1, B2, right? Thiamine, riboflavin right? These are all—niacin—These are all important nutrients. Of course, activated LMTHF folate, of course, methylated B12 or some kind other adenosine hydroxy B12.

Evan Brand: Yup.

Dr. Justin Marchegiani: Uh—chelated minerals like calcium and magnesium and zinc and selenium, right? All chelated meaning they’re bound to specific amino acids, so that we can have better absorption. When we have an amino acid, kind of uhm—they’re next to it, it’s like an escort or a bodyguard for that nutrient to get where it needs to go in the body, if you will.

Evan Brand: Yup. Well said. A lot of these nutrients people are—I’m hearing feedback. What’s going on your end? Maybe your speakers are a bit loud.

Dr. Justin Marchegiani: I’m good on my end. I don’t hear anything here.

Evan Brand: You don’t? Okay. Leave us a comment in the YouTube if people hear the feedback at all, if you hear my voice echoing. A lot of people are so deficient in nutrients, even with an organic diet. And that is something that you and I see and measure on the stool test and then we see and measure that on the organic acids test, too. You know we’ve got a lot of people that come to us because they’ve heard us talking about like a ketogenic diet or some other high-fat diet. But then we can measure something called the steatocrit on the stool test. And so, if people wanna quantify, “Well how am I actually digesting”, “What can you guys teach me about my nutrients?” and “My diet’s perfect, I’m one of those guys, I want to try to fix everything with diet”, well, we can take a look and see if that’s actually working for you. So if we see steatocrit that’s high, that’s a fecal fat marker. You can look at your stool, of course, but it’s better to have a number. And if we see that your fecal fat marker’s high, well, we know we’ve got to give you some good fat digesting enzymes, help out the pancreas help out the gallbladder. And then also on the organic acids panel, we’re going to look at the amino acid markers, so we can see do you have the raw breakdown materials? Coz your proteins—like your animal proteins and pastured animal products—those are all made of amino acids. That’s like the breakdown products. Stuff like those and that’s what fuels your brain chemicals, your neurotransmitters and so, if we see you’re super low on amino acids, that’s a problem. So we have to fix it.

And like you mentioned, why is it happening? Well could be infections like Robert is  uh— he’s a left us a comment here. He is talking about that he’s had Blasto, he’s had Klebsiella, he’s had Citrobacter—

Dr. Justin Marchegiani: Yeah.

Evan Brand: He’s resolved a lot of his infections through Dr. J’s uh—antimicrobials,  which is awesome. I guarantee you are getting robbed for a long time of your—

Dr. Justin Marchegiani: 100%. 100% So the first thing is, right, we have that kind of diet. So think of like your health is like running a business. So every year that you’re unhealthy is like a business, right, having more expenses than its profit, right? Where then its revenue— gross revenue, right? So you’re going a little bit more into debt, a little bit more into debt. The difference is you don’t go into bankruptcy court, right, and go bankrupt. You have symptoms. And those symptoms eventually may lead into a cluster of diseases or pathology whether it’s diabetes or it’s just obesity or maybe it’s cancer or heart disease or you’re just in this in between where you kinda have chronic fatigue, you don’t feel good, you’re kind of depressed.  And then you’re in this in between where you go to the doctor and they’re just like, “Oh yeah, you’re just aging.” or “Here’s an antidepressant.” or “It’s all in your head.” And then you’re stuck with these kinda in between kind of diagnoses where you’re not— you don’t have a disease, but you sure don’t feel good and you’re not getting any answers, right?

Evan Brand: Yup.

Dr. Justin Marchegiani: So that’s kinda the big thing that we see. So we’re like, alright, so imagine that that’s the equivalent of business $1 million in debt. Well just because you start having good business practice and start pulling a profit, you gotta now make above and beyond that million before you start coming back in the black. So that’s where it’s really good for some of these supplements to come in because they kinda, you know, act like a mini bailout or a mini—a mini business loan to kind of bring you back in the balance. So things like B vitamins are great because you burn these up when you’re stressed. And if you have a lot of dysbiotic bacteria, these cre— the good bacteria produce healthy amounts of B vitamins. If you have a lot of bad bacteria, you’re not getting the B vitamins and you’re also getting a lot of toxins, too, which create leaky gut and create more stress and cause you to burn B vitamins and also creates a lot of lactic acid which eats a lot of your B vitamins. So B vitamins are really important first step. And we have B vitamins like B1, which is Thiamine or B2, which is Riboflavin or B3, which is Niacin and B6, which is Pyridoxine 5 Phosphate or Pyridoxine Hydrochloride, B9, which is Folate, uhm—B 12, which is amino, B12, right? Uhm—Methylcobalamin Hydroxyl  Adenosyl Cobalamin, right? These are important B vitamins especially if you’re a vegetarian. B12 is gonna be one of those that you’re missing. So any comments, Evan, on the B vitamins and how important they are.

Evan Brand:  Yes, sir. Absolutely. And I’m gonna address Robert’s question at the same time answering uh—or adding a comment. He said “Can these infections result in high homocysteine levels?” The answer is absolutely yes and there’s a journal that I’ll send over to Justin so we can put it in the show notes. It was American family physician was the literature but it was an article all about vitamin B12 deficiency and basically what happens is whether it’s H. pylori or like they even talk about in this article which is surprising coz most conventional medical people they kinda disregard parasites, but it’s talking about the link between parasites and B12 deficiency and then the link between B12 deficiency in elevated homocysteine levels. So, yes, we may give you some type of supplement, It’s gonna have the B12 like we always talked about. We’ve gotta get to the root cause, too. So we’ve got to fix those infections like I’ve had. We gotta fix those, too, at the same time while supplementing. So let me send it to you, Justin, so we can—we can share with the listeners.

Dr. Justin Marchegiani: That sounds great. I think B vitamins are really important just number one because of the stress component; number two because of the gut bacteria component; and then number three just to kind of—most people are still stressed so they need those B vitamins just to help kind of breakeven every day. So that’s the first component. Uh next let’s talk about minerals. So one of the first important minerals is gonna be magnesium because it’s a mineral that has over 100 or 1000 roles 1000 and enzymatic roles in the body, right? It has a major effect on dealing with enzymes. So with Krebs cycle, with energy, with blood pressure, with mood, with, sleep, with relaxation, with stress. Lots of different roles in the body and it’s one of those that are just incredibly deficient in our food supply. There’s lots of studies on magnesium deficiency and that’s it literally prevalent over 50% of the population. So this is important and if we’re not eating organic, then the magnesium in our food will be lower. So magnesium is one of these things that we wanna make sure is in a high quality supplement. I put it in my supplement via magnesium malate. So it’s bound to malic acid which is a Krebs cycle kinda intermediary nutrient. So it’s really important for the Krebs cycle and that way we can at least guarantee a couple hundred milligrams but because it’s chelated, we you know, it—more of it gets into where it needs to go which is really important. So magnesium is another one of those very important nutrients.

Evan Brand: Good. Well said. Yeah. And if you bought magnesium at Walgreens or CVS or Walmart or Target probably magnesium oxide, we talked about this before, but it’s about a 4% absorption rate. So if you’re taking 100 mg, you’re getting 4% of that; if you’re taking a 1000 mg, 4% of that. So take a look at your supplement bottle, flipped it around and look at the form of magnesium. If it’s oxide, you could use it for constipation that’s about the only benefit. But like Justin’s talking about the to help fuel the enzymatic processes and help Krebs cycle and promote energy and all that, it’s not going to do anything. You’ve got a look at the malate’s; you’ve got a look at the taurates; you’ve got the citrate’s; the—

Dr. Justin Marchegiani:  Glycinate.

Evan Brand: Glycinate, the threonate. So there’s many, many good ones out there. And Mercola, I don’t know if he’s just saying this like anecdotally or if he’s got some literature on it, but  Dr. Mercola’s recent talk about EMF and how he believes that the magnesium can help mitigate the EMF and he’s recommending like 2 g a day.

Dr. Justin Marchegiani: Uhm.

Evan Brand: — of different forms of magnesium. It makes sense, but I don’t know the mechanism of how that would help.

Dr. Justin Marchegiani: Interesting. Well if we look at the big magnesium foods, right? Magnesium is gonna be lower in foods, but it’s gonna be highest in our green vegetables— spinach, swiss chard, uh— pumpkin seeds uhm—you know, kefirs, things like that, almonds, some legumes, avocado, figs, dark chocolate—dark chocolate’s a really good one, uh— banana. Again, you just have to be careful because if you’re kind of having autoimmune issue, more on autoimmune template to start, well, seeds are out, any dairies out, legumes out, uhm— some of these—half your foods are gone.

Evan Brand: Yeah.

Dr. Justin Marchegiani:  So you have to be careful like the big things are gonna be high quality dark chocolate, uh—lots of good greens. And if you can do one of these nuts or seeds like the pumpkin seeds I mentioned, that’s a really good place. But if not, that’s were leaning on a good supplement is gonna be helpful, but the green veggie, I think will be the key uhm—to that. So we just gotta keep in in mind, you know, there may be some foods that are really good for us made nutrient profile but they may have an inflammatory profile that’s— let’s just say, kinda contradicts or kinda—the risk outweighs the benefit of getting that nutrient coz of the inflammation.

Evan Brand: Yeah. I agree. So if you’re autoimmune protocol, if your digestion’s compromised, which it probably is if you’re on an autoimmune protocol coz you probably had an autoimmune illness and that’s what we’re recommending an AIP diet. Sounds like a magnesium supplement will be much— much, much more necessary and helpful. Uh— we had a question from Linda. She said, should she be concerned if every time she goes to the stool, so every time she poops uhm— there’s an oil slick.

Dr. Justin Marchegiani: I don’t know if I would say– I don’t know if I would say scared but concerned, oh, right, yeah. I mean I would be scared if there was blood in the stool.

Evan Brand: Right.

Dr. Justin Marchegiani: Like you know decent bit of blood and it wasn’t just from a tiny bit of a hemorrhoid issue. But if I saw blood in the stool, I would be scared, for sure. I would definitely get that—some kind of a hem—some kind of an ulcer or cancer, make sure that’s ruled out. But with just the slick in the stool, I would be concerned because you’re not digesting your fat which means vitamin A, D, E, K your fat-soluble nutrients like your long chain fatty acids like EPA or DHEA or you know, coconut, good fats like that, you’re not absorbing those which means you’re gonna have blood sugar issues and you’re gonna have malabsorption, for sure.

Evan Brand: Yeah. Absolutely. So in that case, Linda, if you listen to us before, we’ll sound like a broken record, but if not, uh— you know, if you’re working with Justin or I, what we’re gonna end up doing with you would be looking at the stool test, we’ve gotta measure that fecal fat, the steatocrit marker, we’re gonna look for infections. So we’re gonna look for parasites; we’re gonna look for yeast; we’re gonna look for fungus; we’re gonna look for anything that’s gonna be stealing your nutrients or messing up that absorption. H. pylori if that’s suppressing the parietal cells that make hydrochloric acid in the gut. Now your whole digestive cascades is falling apart, we’re gonna look at medications. So if you’ve got a history or your currently taking some type of acid blocking drug we’ve got a factor that in coz that’s such a huge factor for fat digestion, too, if you’re just suppressing that. So we gotta look for those underlying causes but eventually, yes, we could fix the situation and probably add enzymes back in. Let’s address uh—Haley’s question, too, Justin, coz uh—it kinda ties into this. She said that she’s— her digestive enzymes can make your pancreas and gallbladder quote unquote lazy. What are your thoughts? We know that’s not true. With melatonin, yes, you can turn down the production of melatonin if you supplement. But with enzymes, my understanding is we’re only feeding the fire. Justin, can you comment.

Dr. Justin Marchegiani: Well even with melatonin I talked to Dr. Ron Rothenberg about that and he says long as the dose is relatively low that that won’t happen coz it’s a positive feedback loop with these things. But when it comes to hydrochloric acid and enzymes, one of the major feedback loops for HCl and enzymes is gastrin, right? And gastrin when you take supplemental HCl, enzyme levels are –or gastrin levels don’t drop. So it’s not like you get testosterone testicle shrink  in size.

Evan Brand: Yeah.

Dr. Justin Marchegiani: It’s not like that. So my bigger concern is that someone’s not making enough enzymes because they don’t have enough hydrochloric acid in the stomach and my concern is that’s— there’s not enough HCl on the stomach because of the sympathetic stress response, right? That fight or flight from food or from emotional stress or physical stress, so we, of course, we’re fixing that stuff upstream, right? Eating in a good, stress-free environment, not hydrating with food hydrating before, you know, we’re after biting after an hour or two but after, you know, 15 minutes before. And then we’re taking enough hydrochloric acid to lower the acidity so we can activate our own enzymes. But taking something is gonna be great coz I’m more concerned about that food sitting in your gut and not being digested and basically rotting and rancidifying and putrefying, creating stress by sitting in your gut.

Evan Brand: Yup.

Dr. Justin Marchegiani: That’s my bigger concern.

Evan Brand: I agree. So we hit the minerals. You talked about those you did great. We hit our magnesium which is gonna be probably number one. There’s a whole organization dedicated to magnesium deficiencies. If you type in gotmag, it think it’s gotmag.org. There’s like stage 2, 3 and 4 symptoms. You could even have insane symptoms, big issues, heart arrhythmias, atrial fibrillation, all sorts of other like heart-related issues due to magnesium, if you’re deficient. So if you’ve got some heart flutters or some weird symptoms, the cardiologist, they’re not gonna know you’ve got a magnesium deficiency, they’re just gonna end up putting you on like a beta blocker or some type of heart rhythm drug like they’ve done to my grandmother. And they’re not addressing magnesium and these drugs they’re using are likely gonna deplete magnesium even more. So we could get into some really, really big serious health implications if we don’t address something that simple as magnesium.

Dr. Justin Marchegiani: Oh, hundred percent. So again, big source of magnesium, in my line, I have one called Magnesium Supreme. That’s a magnesium malate. That malate’s are– the malic acid so that helps in the Krebs cycle, it helps with energy but also has a relaxation effect. So that’s one of the ones I formulated. I still even like a little bit of magnesium citrate at night. I think it’s great. It may not be the best absorbed, it’s cheaper but it’s still good. So I like my Magnesium Supreme and then we use the Malate— Magnesium Malate in all the multis. And the multi-nutrients Supreme, in the twice or in the Multisuper pack. So that’s kind of what we have. I like those. I use those daily. I think they’re great. And then for kids that may be uh—you know have serious gut issues, we may do like a magnesium threonate kinda gel to help or magnesium chloride kind of uhm—Epsom salt bath, too.

Evan Brand: Nice. And with the anxiety like PTSD, traumas, phobias, the supplement in my line is called Calm Clarity. And I’ve used that one with great success with people especially veterans who come back from war and they’ve just got a lot of emotional trauma or women who’ve been through some type of abuse threonate crosses the blood brain barrier. So that’s another form of magnesium and not any one form is perfect but you can use a combination of these. So like Justin mention, you wanna cycle. Maybe you’ve got some malate here, you’ve got some citrate here—

Dr. Justin Marchegiani: Yeah.

Evan Brand: You can add different forms.

Dr. Justin Marchegiani: Yeah. And then we’ll put show notes and links to some of these things. So if you guys want to support the show, we always appreciate that.  We’re just trying to get you the best information possible. Now, I talked about the magnesium foods. Some of the B vitamin foods, okay? Again, you’re gonna have like if you go online and look you’re gonna see the fortified ones which are gonna be cereals and orange juices which is basically crappy, crappy B vitamins.

Evan Brand: Garbage.

Dr. Justin Marchegiani: The worst quality. So do not count on any of the B vitamins from those foods. And number one, you shouldn’t be eating those foods, anyway coz they’re very high in sugar. With the orange juices and the grains are obviously gonna be the gluten thing which are gonna be inflammatory as well. So cut those out, nix those out. But you’re gonna do really with fish, with vegetables, with fruits, with meats, with leafy greens, egg yolks. So a lot of  the Paleo versions of those are gonna have super, super high amount of B vitamins which is great.

Evan Brand: Yeah. Like Pop Tarts, like fortified with 12 vitamins and minerals. It’s like, “Oh yeah,  let’s just eat pop tarts, high fructose corn syrup and genetically modified glyphosate sprayed wheat flour. We’re gonna be just fine.” Not true, not true, not true.

Dr. Justin Marchegiani: Remember, when you take in a lot of sugar and refined carbohydrate, all that refine carbohydrate converts to sugar and when you look at the Krebs cycle, how that Krebs cycle pumps around and it goes through all these kind of uhm—you know, reduction reactions where all these hydrogens kind of accumulate. It takes magnesium to run those cycles and if you’re basically—if it’s costing you more magnesium to run the cycle than you’re getting in, this is what we call nutrient debt, right? You’re not getting as much from it than you are— for the cost to run it, okay? So keep that in the back of your mind.

Evan Brand: Luckily the human body is resilient. I mean if that— if we we’re like a car, you and I use car analogies, if we we’re at such a nutrient debt like most people are, the car would be dead. But luckily our body will still survive. You just won’t thrive in these situations. You could have hair issues, skin issues, nail issues, like you said, autoimmune diseases, cancer, you’ve got bad skin, you’ve got acne, you’ve got poor sleep problems, you’ve got anxiety, depression, you’ve got chronic fatigue, you’ve got obesity. I mean, a lot of these diseases that have skyrocketed 10,000% over the last 20 years, there’s many, many factors that we can address in one podcast but like you mentioned, just a nutrient— the nutrient density of the soil has been reduced which is why—and I didn’t tell you this yet, but I uh—expanded my property. I bought the acre next door as well.

Dr. Justin Marchegiani: Oh, cool.

Evan Brand: I’m gonna have a 1 acre farm and I’m gonna have as much of my food come from that as possible. Not the meats coz there’s a couple restrictions on having animals but my goal is to provide 50% is my goal. Uh— 50% of my own food. I’ve already grown stuff this year. I’ve had watermelons. Last year, I had bunch of sweet potatoes, I had strawberries, I had broccoli, carrots, all organic homegrown. There’s no more local—

Dr. Justin Marchegiani: That’s great.

Evan Brand: ..that you can get than your backyard.

Dr. Justin Marchegiani: That’s great. And you can even team up with some farmers and make a deal and say, “Hey, you can use my land and I’ll give you half of what’s on there.”

Evan Brand: I know.

Dr. Justin Marchegiani: Coz then you don’t have to worry about it at all. And you kinda make this deal, they get free land but they get half the food. Hey, there’s enough food for you and your family. The rest may go bad anyway, so you may end up giving it away, anyway. So that could be a good deal for you.

Evan Brand: Yeah. I’m gonna try to do some pecan trees and I’ve got all sorts of ideas.

Dr. Justin Marchegiani: Cool. Yeah. Very cool, man. I think it’s important that uhm— people have to understand that your body is like a business. When a business starts having low profits and starts— the revenue starts dropping, the business has to either get incredibly efficient or typically, more than likely, lays people off, right? It fires people, right?

Evan Brand: Yup.

Dr. Justin Marchegiani: And it goes off, it fires people that are least essential to driving the profit. Well, the body does the same thing. It just starts allocating resources to other areas. Some dead skin, it’s okay, we’ll have some irritation, it will get wrinkly and creepy, it’s okay, no problem. Fingernails—weaker, more brittle; hormones will be a little bit lower that means you’ll have a lot of cycles, you know, symptoms with your cycle; you’ll have lower libido; you won’t be able to recover from strenuous work out; you won’t be able to put on muscle, that’s okay, no big deal. And uh—yeah, we won’t—we won’t put it– inflammation as much so you’ll be a little bit more achy, you know, you’ll be little bit more prone to osteopenia or osteoporosis. That’s how the body thinks. Uhm– that’s how it allocates. It’s all about survival. We are really about surviving. So those nutrients help run those systems. We really want to make sure that we have enough nutrients to run systems. There a lot of people they’re focused on calories and if you’re eating a real whole foods those calories will have nutrition, but today, it’s possible with the whole pop tart analogy or the junk food analogy, you can get a whole bunch of calories and not a lot of nutrition on the flipside. So you gotta keep that in mind.

Evan Brand: Agreed. You wanna hit a couple more questions or should we try to move the conversation into some more nutrients. I’ve had vitamin C just echoing in my brain that I have to just talk about vitamin C.

Dr. Justin Marchegiani: Let’s hit that. I wanna hit one last thing on magnesium and we can tie it to vitamin C. There’s a lot of the medications that are out there will actually create nutrient deficiencies. And one of the biggest ones are the blood pressure medications, the water pills, the Hydrochlorothi—Hydrochlorothiazide, the Lisinopril, the ACE inhibitors, right, the beta blockers. These will actually create magnesium deficiency which magnesium is really important for regulating blood pressure, so that actually create more blood pressure, which creates more dependency on these medications. So you can see that vicious cycle. So keep in mind the nutrient deficiency aspect with these drugs. Same thing with birth control pills and B vitamins as well and magnesium. So those are couple of common medications. And then the granddaddy of them all is gonna be the acid blockers that will affect nutrients in many directions, B vitamins, minerals etc.

Evan Brand: Yup. The Omni— is it Omni with an “n” or is it “m”? Omne—

Dr. Justin Marchegiani: Omneprozol. O-M-N-E and then prozol.

Evan Brand: Okay.

Dr. Justin Marchegiani: Yeah.

Evan Brand: That’s great.

Dr. Justin Marchegiani: Prilosec that’s the trade name of it. That’s the—Omneprozol is the generic. So yeah, these are the medications. These are the family of meds we got to be careful of. So, kinda tagging into your vitamin C. I’ll let you the ball with that Evan.

Evan Brand: Yeah. I just wanna—one more comment on the Prilosec.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And the thing that’s scary is these acid blockers used to be prescription and now they’re over-the-counter. So people just go to Target and they just go buy a 48 pack of these, six month supply and they throw that giant value pack 20% more pills into their shopping cart and they just go home, “Oh, yeah, Prilosec.” It’s like, “good God”

Dr. Justin Marchegiani: It’s really interesting because you know you get all the people that say, “Oh, you have to be such a super, super smart medical doctor to prescribe these drugs. They’re so dangerous. You need to have, you know, a medical Dr. kinda looking over you. And of course, that it—that is true with in a lot of cases, yeah, they contradict themselves coz then these drugs seven years later when the patent goes out, once they go generic and there’s no money behind them, they go over-the-counter.

Evan Brand: Oh my God.

Dr. Justin Marchegiani: Look at Ibuprofen, right? It kills 20,000 people a year and now it’s over-the-counter. It’s okay.

Evan Brand: Ugh. Insane isn’t it?

Dr. Justin Marchegiani:  Yeah. So I mean, you kinda talk on both sides of the mouth and you know, we pointed out. Uhm so, yeah, in general, the medications that you’re gonna see that are gonna be out there, primarily are gonna be the patented ones. Once that seven-year patents off or if they can create a mini-me version of it, then it’s over-the-counter and anyone can buy it. It’s up for grabs now.

Evan Brand: Fortunately, beta-blockers and antidepressants are still prescription only. So, that’s good. We’re saving a lot of issues with that. But yeah, let me get back on subject. Vitamin C is huge. It’s gonna be stored in the adrenal glands, typically.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So Justin and I are gonna  measure your nutritional markers when we run organic acids testing on you. We’re gonna look at a lot of nutrients. Nine times out of 10 vitamin C shows up low because people burn through it like jet fuel, just like B vitamins that Justin mention about stress, same thing with vitamin C. There is a reference range most people aren’t even on the map. I’m seeing people at like a point level, like a decimal point level when they should be hundreds of times higher. So I’m typically gonna be using about 2000 mg and I’ve had people say, “Oh Evan, I’ve taken vitamin C for years they still show up low because they were using some garbage they got at like a health food store. Even thought it’s a health food store could still have inferior quality or it’s a consumer break— consumer grade product they bought at Whole Foods or Amazon or somewhere else. And they’re not using professional grade or they’re just using ascorbic acid only, which is decent. But to really boost up the levels, you’ve got to have the antioxidants with it. The quercetin, the rutin, the bioflavonoids.

Dr. Justin Marchegiani: Mixed ascorbate.

Evan Brand: Yeah. You gotta have the mixed ascorbates, too. You’ve got the magnesium ascorbate, the calcium ascorbate, the sodium ascorbates. If you just do—like  what is it? emergency that garbage that they sell at the check out line at Walgreens or other places where it’s not only is it just rate ascorbic acid it’s got fructose in there, too, which is gonna destroy blood sugar. That’s not gonna do anything. You could buy a year supply of that and not move the needle. Dr. Justin Marchegiani: Hundred percent, man. So may—uh—Vitamin C is really important. I also say selenium is one of these things that are very important as well because it’s important for thyroid conversion. Uhm— it’s important for liver detoxification, it’s important precursor for glutathione, right? And we like to give that neither like a Selenium Glycinate or Selenium Methionine kinda bound to one of these sulfur amino acids.

Evan Brand: Let me ask you this.

Dr. Justin Marchegiani: Yeah.

Evan Brand: What do you say to all these people, “Oh, Justin, I don’t need Selenium. I eat three Brazil nuts per day.

Dr. Justin Marchegiani: Well I mean I think that’s a really good source of selenium; the problem is the amount of selenium in those brazil nuts can vary tenfold. So you could either be getting 50 µg or 500 µg. So the problem is you just don’t know how much you’re getting in each of them. So I think it’s good if you wanna do a Brazil nut or two a day.  Just make sure that the uhm—the multi you’re taking guarantees you at least 200 µg of selenium per day. And I think you’re in a really really, good place.

Evan Brand: Yeah. And we talked about the absorption issue. So if somebody has got some gut bugs, doesn’t matter if you eat the Brazil nuts. You could probably eat a whole bag and not boost up selenium, if you’re deficient and you’ve got things stealing your nutrients or compromising your digestive quality.

Dr. Justin Marchegiani: Exactly. And it’s just good to have that insurance policy with selenium. Uh—it’s gonna be hard to overdose with it if you’re in that 2 to 400 µg range and you’re using a good quality like Selenium Methionine. You’re gonna be in really good shape. And again, just kinda tag teaming, we got a lot of people talking about hormone stuff. Selenium is really important for hormones especially testosterone and then we even have Zinc, right? Whether it’s zinc aspartate or zinc methionine or uhm— zinc’s really important. The zinc fingers have a lot to do with the genetics like the DNA the epigenetics. So having enough zinc is really important to activating— having good affects our epigenome. Zinc is extremely important for making HCl. It’s a really good building block for our sex hormones as well. So gotta love zinc and when you’re stressed and you have low hydrochloric acid level, zinc can go low. And you can do is a tally test. We do some Zinc Chloride or—is it Chloride or Sulfate? I was getting confused.

Evan Brand: I think Sulfate for that.

Dr. Justin Marchegiani: Yes. So Zinc Sulfate. We could do a Zinc Sulfate test. The more metallic you’re tasting it is, the better— the better your Zinc is. The better or the more neutral taste, the lower your zinc is. That’s a good little kind of rule of thumb test.

Evan Brand: So people heard that, they’re like, “What the hell is he talking about?” So basically, uh—Justin and I can send a high-quality liquid Zinc Sulfate and based on the status of your zinc, that will change the flavor of the zinc. When I took this test a few years ago, I think they say, “hold it in your mouth for up to 30 seconds” So you put a little bit zinc in your mouth, you kinda gently swish it around. I swallowed it,. I tasted nothing. That was when I had all those infections. I literally tasted nothing. It tasted like water.  My zinc was trashed and then as you improve infections, you get your digestion better, your supplementing with the right type of zinc, all the sudden you could put the zinc in your mouth and then it almost tastes like your licking a piece of metal like right away. That’s the goal but would you say, Justin? 95% of people they’re not going to taste the metal right away which means they’re super deficient.

Dr. Justin Marchegiani: Yeah. I mean a lot of them are gonna be deficient if they have gut issues or stress issues or malabsorption those kind of thing for sure. So I think that’s a really important one look at. So we hit the Vitamin C, we hit Magnesium we hit Selenium and we hit Zinc.

Evan Brand: I’d say Omegas and vitamin D would be two others we have to mention.

Dr. Justin Marchegiani: Yeah. I think Omega-3 is really important which is—the typical Omega-3 fatty acids there is ALA Alpha Linolenic Acid. That’s the omega-3 in flaxseed oil. We have EPA which is 20-chain carbon which is Eicosapentaenoic Acid, that’s EPA. And then we have the_ DHEA. These are the 20 and 22. The EPA or the DHEA are the fats found in fish oil. These are the really important ones. These have all of the anti-inflammatory action. They help block this prostaglandin E2 pathway which gets inflammation jacked up. They also are really good building blocks for the brain and the neurological system. And the ALA are the Alpha Linolenic Acid from the flax seeds and the vegetables, that actually has to get converted via this enzyme, I think it’s Delta 5 Desaturase. And that enzyme converts the 18 carbon to the 20 carbon and things like insulin resistance and inflammation and stress can affect that conversion and knock it decreased function by 80 to 90%. So you’re not getting those really biologically active omega-3 fatty acids when you’re doing a lot of the plant-based Omega-3’s because of those mechanisms I mention. So getting the really good Omega-3’s from the fish is going to the best way. Plus the fish actually bio accumulate how the plants get it which will typically is the algae, right? A lot of the good vegetable, Omega-3 supplements vegetarian ones are gonna be algae based. Well the fish concentrate the algae. It’s kinda like the grass that cows concentrate the grass. So you’re kinda getting that bioaccumulation in a more concentrated form when you’re doing some of these really good fish oils.

Evan Brand: Well said. Yeah. Pastured meats, too, you will get some— you will get some fatty acid. So your bisons, your elk, which are my two favorites.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Your grass-fed beef, pastured pork. I would assume you’d get some from pork.

Dr. Justin Marchegiani: Yeah. More than likely you’re gonna get some from any of the animal products. The healthier they are, the more pastured they—the more pastured, the more biologically appropriate their diet is, uhm— the better chance that you’re gonna get more of these Omega-3 fatty acids than the more inflammatory Omega 6. But again, Arachidonic Acids are really important building block which is an Omega-6 fatty acid, but that’s gonna be a really good fat, too. So you don’t want to say, “Oh, all Omega-6 is bad. It’s just gonna really be a lot more  of the Omega-6 that are gonna be driven from vegetable oils like refined vegetable oils, right? The good vegetable oils are gonna be olive oil which is a—a Oleic Acid which is really an Omega-9, your—your uhm—short chain fatty acids are gonna come from your butters and ghee which that’s gonna be more animal-based. MCT oil or your Caproic, Caprylic uhm—Lauric acids. These C6, C8, C10, C12 fatty acids, these are gonna be in the coconut. That’s great. Uh—so those are gonna be some of the really good ones to start with. All avocado oils, another really good neutral one as well.

Evan Brand: Yeah. I just wanna point out the fact that we’re hitting a lot of really good foundational nutrients but we could do entire episodes just on magnesium, just on vitamin C.

Dr. Justin Marchegiani: Yeah. We have that on magnesium. I know that.

Evan Brand: I think we did. Yeah. So if—if we feel like we’re glossing over some deep aspects, then that’s okay. The vitamin D that’s huge. It’s really a hormone called vitamin but vitamin D is important we like to your levels at preferably 60 or above. I say nine out of every 10 people are gonna. be deficient in magnesium As you get older, you can’t convert sunlight into usable vitamin D as much. So even if you’re getting plenty of sun exposure which I’ve talked to people who garden for six hours a day, they are still deficient in vitamin D. And so in less— you’re like Dr. Mercola, where he said he hadn’t supplemented in seven years, something like that, 5-6-7 years, he lives at a very south latitude in Florida. He’s out on the beach hours— three hours a day with so much skin exposed and he keeps his levels at about 60. So I unless you got that amount of time and lifestyle to dedicate—

Dr. Justin Marchegiani: Totally.

Evan Brand: ..to sun, it’s gonna be really tough to keep it at adequate level.

Dr. Justin Marchegiani:  I hundred percent agree. So Vitamin D is really important. We try to do it with actual sun exposure, uhm— don’t burn, kinda get your Minimal Erythemal Dose, MED, if you will. And uhm— supplement the rest. If you can— if you just do a really good 25 hydroxy vitamin or a regular vitamin D3, mine’s uh—Emulsi D Supreme and it’s got the uh—MCT oil and the vitamin D3—D3 in there which is a really good form. Again, you can also add some K2 in it. My biggest issue is you don’t get enough vitamin D with the K2 ones but just make sure getting some really good K2 in your foods which fermented foods are  gonna have a lot of K2 uhm—a  healthy gut bacteria makes some K2 and then also a healthy grass-fed butter or ghee are gonna be other excellent sources of vitamin K2 as well.

Evan Brand: So Designs has one that’s got 5000 IU of D+ K warning K2. I can’t remember the name.  But it’s a pretty good one and I’ve used it before think. I think—I think it’s gonna be called the Su—I think it’s Supreme.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: That’s what is it. D Supreme.

Dr. Justin Marchegiani: Yeah. The problem is the vitamin D levels in it are very, very low. That’s the only issue.

Evan Brand: I think it’s a 5000. What are you—what are you talking about using? You talking about using 8 or 10 thousand or is 5,000 good in your eyes?

Dr. Justin Marchegiani: It just depends. I like doing the liquid Vitamin D just because if I need to use it therapeutically like someone’s sick, right? I may do 100,000 IUs—

Evan Brand: Yeah.

Dr. Justin Marchegiani: And that ends up being like 20 or 30 pills. It becomes doing too hard, so it’s easier to take like 30 or 40 drops put in your smoothie and you don’t even know you had it.

Evan Brand: Well said.

Dr. Justin Marchegiani: I go more with the liquid, but again, your great vitamin K sources are gonna your green leafy’s, fermented foods like—like Natto, of course, Brussels sprouts, cabbage, broccoli, fermented dairy, prunes, uh—high quality uh— grass-fed butter or ghee. So you really, you know, you can get a lot of those uhm—make sure you’re getting a lot of good nutrients from those foods. Make sure their organic and that will help significantly. So if you’re doing a vitamin D, you really want to make sure that K2’s there and make sure those foods are really good in your diet and a lot of good multis and have a little bit of K2 in there, too.

Evan Brand: Good, good. Well said. Shall we look at a couple questions here?

Dr. Justin Marchegiani:  Yeah. Let’s hit them.

Evan Brand: Okay. So uh—we had a question about Mercola’s complete probiotic. It’s probably decent, Justin and I use professional grade. So if there’s a consumer grade product out there, we’re always gonna say ours is better because we’ve got healthcare manufacturers that make our products. There is very, very, very stringent restrictions in testing and manufacturing processes that we use and so were always going to push you towards our probiotics instead.

Dr. Justin Marchegiani: His is probably good, though.

Evan Brand: Yeah. I’m sure their good. I mean Mercola’s, you know, he’s very detail oriented. So I’m sure his are good but we’re biased. So we’re gonna want you to buy ours.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So you could check out uh—justinhealth.com Check out his line. He’s got several in the gut support section and I’ve got a few formulas, too, that I’ve got on my site evanbrand.com You can check out those.

Dr. Justin Marchegiani: Perfect.

Evan Brand: Alright. Let’s keep going. What else as we’ve got here? Uh— Robert he asked, “What foods and supplements can you take to speed up restoring low secretory IGA?” What do you think? I think a lot of the gut supports like the leaky gut formulas, your slippery elm, your marshmallow roots, chamomile flowers, anything that’s kinda fix a leaky gut situation maybe some mushrooms to support the IGA for the immune system.

Dr. Justin Marchegiani: Yeah. I think making sure the infections are gone, number one. Making sure the diet’s good. Making sure you’re breaking down the foods that you’re eating. Uhm— number three, once the infections gone, adding in a lot of the healing nutrients.  So in my line, we use one called, GI Restore, which is a lot of those same nutrients. Uhm—it’s got the glutamine, it’s got the slippery Elm, the aloe, the DGL, a lot of the healing, soothing nutrients. Getting the probiotics up is gonna be really helpful, you know, the Lactobacillus, the Bifidobacter strands, various strands there. Also very high amounts Saccharomyces Boulardiis is proven to help improve IgA levels. So those are really good things that you can add in there. And just making sure the adrenals are supported.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Because a healthy cortisol levels have a impact on your immune system which has an impact on your IgA. Coz your IgA is that mucosal that first-line defense for your immune system.

Evan Brand: Yes. So chronic stress, too, right?

Dr. Justin Marchegiani: Yeah.

Evan Brand: If you’re taking all the supplements in the world but you have a terrible boss and you hate your life, you’ve got to address that chronic stress component coz that’s gonna be the number one cause that’s going to drive down the secretory IgA.

Dr. Justin Marchegiani: Hundred percent.

Evan Brand: Uh—there’s another question here. There was a supplement a person had to had a tiny bit of soy lecithin in it should they be concerned? What’s your take?

Dr. Justin Marchegiani: I wouldn’t worry about soy lecithin. It’s tough. Uhm—soy lecithin is more of an emulsifier. It’s more to help with the digestion and the mixing of that product is typically not gonna be soy protein in that.

Evan Brand: Yeah.

Dr. Justin Marchegiani: The soy protein is really what causes the problems. Lecithin’s more of an emulsifier. So as long as it’s a good quality product uhm— I’m okay with there being a little bit of soy lecithin in there.

Evan Brand: Yeah. And I’ve got a couple formulas that have it in there. I’ve had people say, “Oh my God, I’m allergic to soy.” They’re fine. They have no issue. that’s not actually— it’s such a— it’s such an extracted form that it’s not like you’re eating soy. You’re not eating soybean.

Dr. Justin Marchegiani: Right. And then in my line, I think I may just have a few that have soy lecithin in there. But we were able to make sure that it’s guaranteed that it’s non-GMO soy. So you really want to make sure it’s at least non-GMO soy lecithin. And as long as that’s there, I’m okay with it.

Evan Brand: And it’s gonna be a tiny amount. When you look at the formula we’re talking and the other ingredients, it’s not an active ingredient. So could be 1% of the formula.

Dr. Justin Marchegiani: And less, you know, single digits fraction of percents for sure.

Evan Brand: Yup. Good. What else we’ve got here? If you feel like hitting this and we can, we can save it for another day—symptoms of chronic intestinal infections. I think we hit on that already with the hair, the skin, the nails, the acne, depression, anxiety, fatigue.

Dr. Justin Marchegiani: Yeah. All your— all your common symptoms, right? Your uhm— your intestinal symptoms: bloating, gas, diarrhea, constipation, bloating, acid reflux. And then your extra intestinal which are all the mood-based and energy-based: fatigue, mood, joint pain, depression, anxiety. Those kind of things, sleep,—

Evan Brand: Autoimmunity—

Dr. Justin Marchegiani: Hormone stuff, autoimmunity. And we got a whole podcast on that. So just google digestion or parasites or leaky gut and you’ll get a whole bunch of podcast and videos on that topic.

Evan Brand: Cool. Robert said he loved our podcast on histamine and it hit home prior to having infections no foods were problem, uh—post infection, fermented foods read havoc on him. So thanks for the podcast. Thanks for the feedback Robert. We love to hear that the histamine podcast was a killer one.

Dr. Justin Marchegiani: Yeah. I’m looking forward to chatting with you soon, Robert. I know uhm—you’ve been doing good work on your— on yourself there with uh— some of those good informational put in the podcast. But if you need more support, let us know. I’d get retested. Make sure we get to the root cause coz if those issues are still there with the post histamine stuff, there may be some additional critters hanging around.

Evan Brand: Yep. I agree. Another question about chronic dry eyes. “How often have you seen this with your patients? I’m working on healing the gut do you think there could be other root causes to dry eyes?” Justin, what’s your take?

Dr. Justin Marchegiani: Yeah. Chronically low cortisol. You’ll see load—you’ll see dry eyes. Typically, get your diet stable. Once your diet’s stable, you can add a lower carbohydrate kinda diet. If those dry eyes are still there, gently taper out that carbohydrate every couple of days. You know, 10- 15 g of carbs primarily at nights. Do the safe starchy versions: squash, sweet potatoes, plantains, those kind of things. And you may see those dry eyes start to go away. You can even try a tablespoon of coconut oil and a teaspoon of honey, right, before bed as well that may help.

Evan Brand: Cool. So what else we’ve got? “Can I re-infect myself with H. pylori with makeup like lipsticks that I’ve used when I had H. pylori? I’ve no idea what the lifespan of that is on the product.

Dr. Justin Marchegiani: It is possible. I mean I would just look at uhm—the lipstick stuff. Maybe just get a razor blade and cut that end off there. I think you’d probably be okay with that. Uhm— typically, you know, as you knock out the infection, you know, you’d still be using it. So eventually, you’d wear off that but I think if you wanna be on the safe side, I think that’s a good thing to keep in mind.  Even more important uhm—things that you can quite excise as easy like partners, right? Spouses. Ideally getting them at least treated semi- “semi” meaning maybe we only use one supplement just coz the compliance is so important. I would really be more—more imperative on the spouses and the partners.

Evan Brand: I agree. Partners are probably much bigger issue, much bigger carrier and reinfection source than your makeup and lipstick. I don’t know of any high-quality lipstick. Maybe they’re out there, but I would just throw that stuff away and maybe does discontinue using lipstick, too. I doubt you’re missing out on much in you know it’s— there’s parabens and all sorts of other stuff.

Dr. Justin Marchegiani: Yeah. And they have some really good things on the market now that do a lot like food-based ones where they are like extracting cherries and all these different food-based ones that kinda produces the fruit-based stain and kinda gives you a similar look but it’s using nutrition and foods versus, you know, some of the synthetic things.

Evan Brand: Uhh..okay, okay. So maybe you— maybe you stick with the lipstick then. Alright. James said he had a over sympathetic—let’s see having over sympathetic with sexual activity does blood pressure med Norvasc affect ED issues? That’s kinda like—I don’t even fully understand what you’re saying coz it’s kinda like a piece together thing. Are you understanding what he’s asking?

Dr. Justin Marchegiani: Yeah. I think what he’s saying is those medications have a potential side effect of erectile dysfunction? I would just go to RXlist.com and put that medication in there and look at that long list of side effects. I can—I can do it from right here while we continue with the conversation. What was the medication called again?

Evan Brand: It’s N-O-R-V-A-S-C. Norvasc.

Dr. Justin Marchegiani: Okay, cool. I’ll pull it up here in a second. N-O-R-V-A-S-C?

Evan Brand: N-O-R-V-A-S-C. as in Charlie.

Dr. Justin Marchegiani: Norvasc. Got it. Okay, cool.

Evan Brand: Then he’s saying, even with Viagra, it doesn’t correct lack of sensitivity.  So, yeah, I mean here’s my easy quick answer. If you didn’t have those symptoms before  and now you’re on this drug and those symptoms are happening, how could that not be a factor?

Dr. Justin Marchegiani: Yeah. This is a an—an—Am—Amlodipine, which is a basically a calcium channel blocker, okay? Which is a calcium channel blocker, which again, magnesium kind of does the same thing, FYI. And if we look at the side effects, uh—feelings like you may pass out, swelling in your hands feet and ankles, pounding heart beat or fluttering on your chest, chest pain, heavy pain spreading arms and shoulders, nausea, general ill and there’s more uhm— side effects as well. So—

Evan Brand: It’s like a commercial all of a sudden.

Dr. Justin Marchegiani: I know, right? Let me see here: dizziness, drowsiness, tired, stomach pain—

Evan Brand: What is this—what is that? That’s for blood pressure? Is that right?

Dr. Justin Marchegiani: Yeah. This is for blood pressure medication, but I think what you said is the best advice if that wasn’t there before and then you started taking the medication and it started happening, as long as your blood pressure is not too bad and you could taper down or you could come off with your doctor’s approval, uhm— I would have no problem doing that and seeing if those symptoms improve, then you know. Coz in the end, if it’s not a side effect on RX list.com but you take the meds out and it gets better, does it really matter that they say it is? We know clinically, right?

Evan Brand: Yep.

Dr. Justin Marchegiani: Absolutely.

Evan Brand: There’s so many ways. Didn’t we do a whole podcast—

Dr. Justin Marchegiani: Don’t—don’t come off. If your blood pressure is 160-170 and you’re on blood pressure medications, coz it will go that high afterwards, don’t come off it. You really want to make sure that if you’re on a medication and you wanted to try and see if there’s an issue, one, fix the root causes; but two, talk to the medical doctor that prescribed it and make sure they’re in concurrence—you know, in agreement with you on the taper that you’re going to do. Make sure they are on the same page.

Evan Brand: Yes. Some people they go to the other end of the spectrum where there are so anti-pharmaceutical that “I’m getting off of this.” That’s bad. You— that’s like stroke territory. So don’t do that.

Dr. Justin Marchegiani: You just gotta be careful. Some people if you’re like 130 or 140 over like 80 or 90, not too bad. You could probably come off as long as you’re fixing other root issues, but just have a blood pressure cuff by your bed, test it in the morning, see where you’re at. Just you— you want to do it responsibly. If you do it and you want to get to the prescribing doctor on the same page as you. You don’t want to go rogue.

Evan Brand: Yup. Well said.

Dr. Justin Marchegiani: Excellent. Any other questions you wanna hit up?

Evan Brand: Uh let’s see. What else we’ve got.

Dr. Justin Marchegiani: I have one here. We got one on Facebook here from Michelle or from

Mitchell. “Can L- tyrosine for dopamine support be too stimulating? How much should be taken to minimize side effects?” Yeah. It can be for some people. Uhm— tyrosine can kinda provide precursor supports to dopamine which then above that can go to adrenaline, so it can be. I think starting at 500 mg and working up to maybe, potentially 3 to even 6 g a day is okay. But start low and slow and if you know that it is stimulating, use it more in that first half of the day not the last half of the day.

Evan Brand: Yup. That’s a simple fix. Good answer. Uh—Nora had a follow-up here. “Thanks for answering the question. So can I successfully eradicate H. pylori and other pathogens as if I live with people who have it. Do they have to do treatment in parallel with me?” Well, if you’re sexually active with people, you’re kissing or simple enough, even just sharing straws, sharing cups, drinking after each other, that’s enough to infect them. So even if it’s not a partner, but it’s someone, “Oh, hey, let me have a drink  of that.” That’s enough to still pass H. pylori. Justin and I have seen it hundreds of times.

Dr. Justin Marchegiani: Yeah. The stronger your immune system is, it becomes less of an issue so like with Evan and myself, we have stronger immune systems coz we  work on that. We maybe less prone because our IgA levels are up high enough where the tiny bit of that in your system, our IgA would squash it. But if your IgA is lower and you got more the stress going on and you have poor hydrochloric acid levels, then for sure. That could happen.

Evan Brand: Yeah. And I had low IgA, too. So that’s something that you’d want it measured Nora and check with the stool testing and look for your IGA figure out which your first line of defense is looking like. If it’s low and weak, you’ve just got a lot of chronic stress, then, yeah, you’re gonna be more susceptible to—to pick it up. But to answer the question, “Could you eradicate it?” If you live with other people, yeah, you could but there’s gotta be a lot of things in your favor and you’re not sharing or sharing cups or drinking for most people or kissing them etc. Uhm— Anthony—well there’s one question about—from Anthony. He said, “It’s been over five years with gut issues, irregular stools, many doctor visits.” He found out that he had a whey and casein allergy. “Where should you start to get help?” Oh, wow! That’s a hard one to answer. Uh—right here. Justin and myself. justinhealth.com evanbrand.com I mean we’ve dealt with people who’ve already been to many doctors. I mean it’s such a common story. We always asked the question, “Hey, kinda give us your history. What—what’s been your experience with other practitioners? What have you tried to help? What have you tried that hasn’t helped?” I’d say 90% of people we talked with they’ve already been to a either a Gastro doctor or some other type of doc for their gut issues and they’ve had no success and only prescription drugs like I got recommended to myself anti-spasmodic, anti-acid drugs. If you’ve got a regular Bell’s, man, you’ve got infections. I can put money on it.

Dr. Justin Marchegiani: And I’m a huge believer— I want every patient to at least go in the conventional medical workup before they come see functional docs or functional practitioners like ourselves just to rule out big picture pathology stuff. You know, it just makes it so we at least know that the big glaring stuff is at least been looked at and addressed and assessed. And now we’re looking more functional imbalances which is really what functional medicine is treating. It’s not medicine from a conventional disease based medicine; it’s medicine from a uh— nutritional kind of support perspective working on supporting systems, not treating symptoms and disease.

Evan Brand: Yup. We’ll take one more question here.  Uh from Charlotte O: “How do you feel about NOW foods brand supplements my health coach is using them on me. I think NOW foods is okay it’s once again, a consumer grade product, so it is going to be likely less high-quality. I have seen some fillers and some of their products. I have seen them do some inferior forms of certain nutrients; however, they’ve also got a lot of really good products, too, where they’re stepping up their game in they’re using the methylated bees and the higher qualities with the Omega’s, so.

Dr. Justin Marchegiani: And plus, people doesn’t know. NOW has another line. It’s a higher up line. It’s called “Protocols For Life” That’s their higher-grade line. So if you like NOW, look at Protocols For Life.

Evan Brand: Is protocol uh—will that have to be through practitioner or is that?

Dr. Justin Marchegiani: Couldn’t say it’s a practitioner one but it’s a little bit higher grade but it’s—it’s made by the same company. It’s their one step up.

Evan Brand: But overall what’s your take on NOW?

Dr. Justin Marchegiani: I mean I think they’re okay for certain things. You know, uhm— so as a kind of initial kinda get in your foot in the door kinda thing, I think it’s okay. But of course, you know, we—we have are our bias because were trying to get the highest quality in everything. And part of that is because we actually work with patients face to face. It’s not like they go online and buy something, we never see them again. We’re working with them face-to-face so we have to know that what we’re recommending is the best because we need to seek clinical outcome. So we have to know that. So it’s a little bit different for us because we gotta go all out and make sure that nothing is held back.

Evan Brand: Right. So when you’ve got these other companies and people out there promoting stuff, they’re not working with people one-on-one. So it comes directly back on Justin or directly back on me if we give him our product and it doesn’t work. That’s not very sustainable for us. So that’s why it’s much, much better enough for us. That’s why we have access for people that don’t work with us. We allow other people outside to access our uh—products because they’ve been tried and true and tested. And if they didn’t work with people, we wouldn’t carry them.

Dr. Justin Marchegiani: Yeah. And if it doesn’t work, too, then it allows us to say, “Okay, there’s not some crappy filler or there’s some sub—sub nutrient in there. Let’s look a little bit deeper.” So it gives us the confidence that we just need to look deeper now.  So it’s gonna be on both sides.

Evan Brand: Yeah. And just a firsthand experience with NOW foods and the secondhand, I guess, through clients. I’ve had people taking like their super enzymes, for example, and I get their digestive health markers investigated on the urine and stool test, and it looks terrible. Their digestion is not working at all even with the high dose of their enzymes. So does that mean the quality is bad? Does that mean they’re not dosing it properly? Maybe they’re not consistent as much. I don’t know. Probably a combination of factors, but I always switch over people over to my professional enzymes and then I retest and then all of a sudden, it’s fixed. Is it compliance? Is it quality? Probably both.

Dr. Justin Marchegiani: Yeah. And you know everyone has got their bias and we kinda state our bias there. You know, we’re trying to be uhm— super transparent. Uhm—but yeah, I think there 95% of companies that are out there are bad. But I think that would be in that—I would say they’re in that 5% at least are better, for sure.

Evan Brand: Yeah. Yeah.  Well, that’s it for questions. Anything else you want to hit before we wrap it up. I think we did pretty good today.

Dr. Justin Marchegiani: Yeah. I think James uh—who is it—someone came out there—was it James—Yeah. James asked about Tom Brady. Again, love Tom Brady. Huge Patriots fan. Again Tom Brady does lots of things I would say go back and check out the podcast I did on him a year and a half ago for more specifics but he does use the green stuff. He does kinda promote like a Paleo-Alkaline diet. A lot of people have really uh—let’s just say Tom Brady like have a vegan cook. So because he had a vegan cook, Tom Brady was now on a vegan diet. No. He eats 20% meat. That’s far from vegan, okay? So just kinda keep that in the back of your mind. A lot of misnomers about Tom and he has a lot of a different training uh—modalities, too, that I’m hoping— I would love to get Tom Brady’s coach or strength coach on there.

Evan Brand: Or just get Tom Brady and the coach in a three-way podcast.

Dr. Justin Marchegiani: I would love that, man. I would love to hang out with Tom and get some secrets down. That’d be awesome. I think he may need to wait til he retires to truly unveil some of the stuff. But we’ll see.

Evan Brand: That’s true. That’s true. Well, reach out. I’m sure there’s a media/press person and tell him, “Look, we’ve got insanely popular health podcast. Uh— we’d like to interview Tom and his coach.” But yeah, they’d probably be like, “No way, dude. We’re not giving you the secret sauce, hold on.”

Dr. Justin Marchegiani: I know. I know. Exactly, so— I know Alex Guerrero is— is his—uh  coach that does a lot of the stuff. So I mean— really, really interested to get Alex on a uh— podcast. That’d be freaking awesome.

Evan Brand: Never hurts to ask.

Dr. Justin Marchegiani: No, absolutely, man.

Evan Brand: Well, let’s wrap this thing up.

Dr. Justin Marchegiani: Yeah. We had a great call today. I’m late for my next patient here, but uhm—keep dropping knowledge bombs all day, man. Really enjoyed this call with you. Anything else you want to add or say?

Evan Brand: Well I think we mentioned it all. If people wanna work with us, we work with people around the world. So Skype and phone consultations is what we do and all the lab testing except for blood you do at your house. So if you want to get help, get to the root cause, reach out justinhealth.com or Google  Dr. Justin Marchegiani or myself evanbrand.com or type in Evan Brand. Find us. Subscribe. And if you have more questions, concerns, get a hold of us. That’s what we’re here for. We love helping people. That’s what makes us thrive so we won’t help you thrive, too. So, have a great day.

Dr. Justin Marchegiani: And leave some comments below. If you like this podcast, tell us. Tell us what you like. If you don’t like stuff, tell us what you don’t like. And tell us what you want us to talk about next time and give us a thumbs up. Give us a share. We really appreciate it, guys. And you all have an awesome day, Take care you all.

Evan Brand: Take care.  


References:

justinhealth.com

evanbrand.com

gotmag.org

https://justinhealth.com/products/magnesium-supreme/

https://justinhealth.com/products/emulsi-d-supreme/

https://justinhealth.com/products/gi-restore/

rxlist.com

https://www.nowfoods.com/

 

 

Lowering Histamine Naturally – Getting to the root cause of high histamine – Live Podcast #154

Dr. Justin Marchegiani and Evan Brand engage in a discussion about histamine. Listen as they talk about finding the root cause and driving factor of the issues related to histamine. Learn all about the symptoms associated with histamine issues and find out how problems with the adrenals, hormones, gut, diet and lifestyle contribute to these issues.

Know how some of the medications like anti-depressants, immune modulators and beta-blockers are related to nutrient deficiency. Gain information regarding higher histamine foods and natural supplements. Apply some of the natural solutions and recommendations regarding diet and lifestyle that would address histamine issues.

 Woman-sneezing-due-to-allergies

In this episode, we cover:

04:12   DAO& HNMT: role in our bodies

08:13   Medications and nutrient deficiencies

10:38   Higher Histamine Foods

18:39   Natural Supplements to lower histamine

21:57   Toxic mold

28:42   Diet and Healthy enzymes

 

 

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Dr. Justin Marchegiani: And we are live on YouTube. Evan, to it’s Dr. J here. How are we doing today, man?

Evan Brand: Hey, man, Happy Wednesday! You and I have been pulling out the research books today. We’re like, “Hey, let’s make sure we know everything as— as much as possible about histamine.” A few have been asking you, asking myself, you’ve done interviews with histamine experts and what was it, the histamine chef is that who you chatted with?

Dr. Justin Marchegiani: Yeah. Yup. Yasmina Ykelenstam. She’s the histamine chef and we did a podcast last year on this topic. And uhm lot of good stuff, we’re kinda rehash some of the key take homes, we’ll talk about getting to the root cause and we’ll also talk about ways that we can supplement and just support histamine issues in general, more specifically.

Evan Brand: Yeah. So what you and I were talking about affairs. We— we don’t really market ourselves necessarily, it’s like, “Hey, histamine practitioner” There’s a lot of people the kind of attached the word “histamine” to their name or to their marketing efforts, but, you and I, as we start to dig deeper and find root causes of the histamine intolerance which we’ll talk about exactly what this means, we’re fixing histamine intolerance just as a side effect of doing all the other good work we’re doing to support the adrenals and support the immune system and ensuring that people are free of infections and fixing neurotransmitters like all the stuff, Oopp, it just happens to fix histamine intolerance.

Dr. Justin Marchegiani: Exactly. Like in the functional medicine world, you know, there is ways that you can market to so you can kinda row people in specifically coz you talk to their issues, but again, if you really are a good functional medicine practitioner, clinician, you’re hitting all of the body system. So in general, you’re not gonna really miss anything but there are ways that we can dive in deeper to issues such as histamine. And we’re gonna try to do that today. We’ll kinda zone out a bit. So we have like the big picture perspective, so people don’t forget what the root causal things that can’t be ignored are, and then we’ll also talk about you know, palliative things we can do on top of just the—the functional medicine principal stuff to get even better results.

Evan Brand: Sure. So should we start with some symptoms? What exactly people are noticing when they’re coming to us and they’re saying, “Hey, I think I have a histamine issue and I believe it could be coming from my diet.” We’ve got symptoms like headaches, could be anxiety, it could be your face flushing, it could be an itchy tongue or runny nose. What— what else am I missing symptom wise?

Dr. Justin Marchegiani: Yeah. Headaches. All those different things. It could be flushing, it could be even hives or the eukaryotes, those wheels that come up on the skin uhm— those can be all, you know, things that are happening. And again, what’s histamine doing? Histamine is a neurotransmitter. And there are various receptor sites for histamine in the body. There’s you know, H1 or histamine 1. Histamine 2, 3 and 4. And again, these things can control for instance, smooth muscle and endothelial tissue that affects blood vessels. This is what like Benadryl and like Claritin would—would utilize. So if you have like an allergic reaction and like your skin get super blown up, right? That’s why you do like Benadryl, right? Or histamine two controls acid secretion and abdominal pain. So histamine can also increase acid as well. It can also increase the heart rate. Histamine three has an effect on controlling the nerves, sleep behavior, appetite. Histamine four has an effect on the intestines, the spleen the colon, white blood cells and the inflammatory response. So it’s kind like this, right? You take your hammer; you whack your thumb, and all of these different reactions that happen, right? So you can look at all of the clotting factors and the cytokines and all of the inflammation and the white blood cell mobilization. And if you just kinda zone back, zone back, zone back, what caused it all? The hammer. So we’ll kinda zoom in, alright, what’s happening and the nitty-gritty, but then we’ll kinda zoom out and say, “Okay, what’s the hammer in this analogy?”  Coz if we can focus on the hammer, it’s way easy to wrap your head around, “Don’t whack your hand—don’t whack your thumb with a hammer than it is to look at all of the nitty-gritty. But we’ll kinda do both. So people that are looking to nerd out a little bit, kinda get satisfied and the people that just want the action items get satisfied, too.

Evan Brand: Sure. So let me just pronounce what we’re actually talking about. Diamine Oxidase also known as DAO, so basically, this is an enzyme that we’re making on our own in our body which is basically just like when we’re talking about proteases and lipases and lactases and just different digestive enzymes. DAO is an enzyme that’s basically going to find, it’s gonna seek out like the CIA, it’s gonna find the bad guy which is gonna be excess histamine in your foods and it’s can help break those down it could be foods or beverages so we’ll talk about the alcohol component in DAO when it works properly, it can break down up to 99% of the histamine. And then there’s 1% of histamine that actually enter circulation but we’ll talk about some of the root causes here. There could be going on with the gut. When you’re deficient in DAO, which is why you can supplement, which Justin told me off air, “Man, this stuff is sold out everywhere.” But when you’re supplementing with it or you’re fixing the root causes, and your getting your DAO in time to be back in adequate amounts, you’re able to break down the histamine and you no longer have histamine intolerance, which is why people can take DAO supplements and they can feel better but you’ve always got to work back to the root cause of other issues why is it not working in the first place.

Dr. Justin Marchegiani: Yeah. It’s also this DAO which is Diamine Oxidase and there is also another one called HNMT Histamine N-Methyl Transferase and these both have an effect of breaking down histamine. So if we take off our functional medicine root cause hat and we put on our palliative natural medicine hat, we wanted to just control symptoms, well, we can give enzymes like DAO which has been backordered for years. They are typically extracted from kidney or thymus tissue and big back order for a while, but we can give those to help lower histamine, alright? Coz that enzyme helps break histamine down so, you know, it’s like someone that has a lactose intolerance issue, they may take Lactaid which is milk enrich with lactase, the enzyme, right, to break down the milk, the milk sugar and they have less diarrhea. So kinda into that perspective where we’re adding in the enzyme to be able to break things down uh— which can be helpful from a palliative perspective. Uh— number two, we can avoid— we can make sure we have all the nutrients required to make a lot of these enzymes. So like the HNMT enzyme, we need SAMI, right? We need SAMI, S- Adenosyl Methionine which is really important for MTHFR. Uhm the Diene Oxidase we also need B6, we need copper, some of these other enzymes to for histamine processing, right? We need B2; we need iron; we need B5, right? And a lot of these nutrients we’re also gonna deplete with adrenal dysfunction, too. So you can see how adrenal issues and low histamine can be affected. Anytime you see B vitamins we know how important healthy gut bacteria is for producing B vitamins. So you can see, if we have a dysbiosis or SIBO, we have food allergens driving inflammation, driving leaky gut and/or gastrointestinal permeability, that can all affect our ability to make enzymes to lower and process histamine.

Evan Brand: Well said. So any gut infection, I mean, Justin and I that’s one of the things that we work on so much because it’s so common you probably heard our stories but, you know, I had H. pylori, I had parasites, I had bacterial overgrowth, I had yeast and all that’s driving leaky gut. So if you got something like H. pylori, for example, which we see every single week on lab results when we’re looking at people, the H. pylori is going to suppress the stomach acid and so if you’ve got undigested food, even that alone, could be causing leaky gut, therefore causing low DAO, therefore causing you to have “cortical histamine intolerance”. So if you work with a practitioner on histamine, we’ll talk about the diet piece in a second, but you’ve got to get the gut in healthy spot. You’ve got to fix the—the diet. Make sure that the gluten is out of the diet, or anything that could be causing a leak ego situation; otherwise, you’re just setting yourself up for failure. And then, surprisingly enough, which maybe you know more about this than I do, but it’s interesting that a lot of these medi—medications, I don’t know the mechanism but like antidepressants like Cymbalta, Prozac, Zoloft, you’ve got the immune modulators like Humira and Enbrel. You’ve got the Metaprololol, the beta-blockers; you’ve got Zyrtec and Benadryl. All of these things are causing the DAO enzyme to become deficient. I mean I guess the mechanism isn’t too important but it is interesting.

Dr. Justin Marchegiani: Well I think some of the mechanism pretty straightforward. Uhm— a lot of this is via nutrient deficiencies. A lot of these medications create nutrient deficiencies and a lot of these nutrition these nutrient deficiencies and a lot of these nutrition deficiencies revolve primarily around B vitamins and minerals. So it makes sense. If we create deficiency with B vitamins and minerals, of course, that’s gonna create more issues. I mean it’s like blood pressure. If you look at the acid block—the beta-blockers or the uhm—water pills like hydrochlorothiazide or the Lasix.

Evan Brand: Yup.

Dr. Justin Marchegiani: They are either diuretics but they create deficiencies with potassium and magnesium, which are really important for blood pressure. So you can see a lot of these drugs actually can make the problem worse. It’s an amazing business model if you’re only looking at you know the money factor, but if you’re looking at fixing the root cause, like we are, it’s definitely not good. You wanna really back up.

Evan Brand: Agree. Well said. You wanna talk about diet?

Dr. Justin Marchegiani: Just to kinda—just to kinda back out just a little bit. Uhm—we talk about the nutrient deficiencies, right? We talked about medications and antibiotics, antacids, antihistamines, right? Uhm—We talked about uhm—well, I’m gonna add it, nutrient stressors. So if we have more stress, more adrenal stress, more fatigue, poor sleep, inflammatory diet, that’s gonna drive more in a higher increase in histamine. If we have hormonal imbalances whether we’re estrogen dominant or that we have adrenal dysfunction, right? Imbalance in our stress hormones, cortisol, rhythm issues, a lot of that’s gonna be driven by a lot of these lifestyle stressors. That’s gonna really create more histamine issues. Now, I always backup. How do we know someone has a histamine issue? Well, do they have any of those histamine symptoms we mentioned in the beginning? Coz we know histamine does a few things. It helps increase heartbeat; it helps with gastric acid secretion; it opens the blood vessels, hence why when, you get allergies or allergic reaction, you swell. It helps increase bronchial dilation; it helps with gut permeability; it increases adrenaline. But if people get headaches or flushed or rashes or headaches with higher histamine foods, we definitely take notice. And those higher histamine foods, the big one, is going to be fermented foods. Do you get worse with fermented foods? Do things like teas create, you know, problems? If you have bone broth, does that create problems? Does citrus fruits create problems? Do meats over, you know, they’re too old, create problems? Uhm—does chocolate and coffee create problems? So if we start seeing issues with some of those symptoms, I really look a little bit closer to see what could be the driving factor.

Evan Brand: Yeah. I’ll list down a couple of more, too. Kombucha—that’s gonna be popular for our crowd, our community.

Dr. Justin Marchegiani: Yup.

Evan Brand: Yogurts, even if it’s like a grass-fed yogurt, your sauerkraut, if you’re having flare-ups, I’ve had some women that said have flare-ups on their skin after doing sauerkraut, that’s a sign right there and then alcohol, too. So wine, beers, champagnes even if it’s organic wine, it’s not gonna matter. Cured meats— so salami, could be pepperoni, the beloved bacon—bacon an issue, unfortunately for the time being. You mention the citrus fruit, aged cheese and then nuts— walnuts, cashews, peanuts, avocados. I believe— I don’t know if it was histamine, but I had something going on where I had to pull out avocados for like six weeks. I was having headaches from them. It was no other foods. It wasn’t any other nuts and seeds but I believe I had—I’m gonna guess a histamine issue because why else would avocados give me a headache?

Dr. Justin Marchegiani: Oh, exactly. Yeah, totally. So—

Evan Brand: I was doing like everyday they’re so good and so easy to add to a meal, so.

Dr. Justin Marchegiani: Totally. And then we also have things like mast cell activation disorder, right? Histamines produced by mast cells, so you got these like basophils, which are like in our white blood cells, right? They’re like one of the smallest amount of white blood cells are basophils. And these basophils go into our blood straight to our tissue. They become uhm—mast cells. And these mast cells will produce histamine, alright? So then you have this thing like called mast cell activation disorder. So like the more inflamed you become, right, the more your body tends to dysfunction. And—and you get more names for that kind of inflammation whether it’s IVD or IBS or mast cell activation disorder or some type of you know, allergic issue or some type of autoimmune issue. You can just go through all the different names. The more inflamed someone gets, the more symptoms. And basically diseases are nothing more than grouping a constellation of symptoms together. That’s why it’s funny when people tell me, “I just need a diagnosis.” Well, a diagnosis is nothing more than someone in the medical field taking a set of symptoms that have been, you know, trace for you know, many, many years into a disease name and someone studied and published. But it doesn’t do anything, it just basically groups these symptoms together and maybe there’s a drug for it, which is typically how a disease, you know, gets name because of the drug or treatment for the most part. But in the end, does it really help you fix the issue? A lot of times, “No”. But it gives people relief to know that it’s something, but again, if you’re depressed and you’re stuck on antidepressant your whole life, well, do you really feel good about that if you’re not fixing the issue? Maybe not.

Evan Brand: Right and I had a—I had a diagnosis of IBS, right?

Dr. Justin Marchegiani: Yes.

Evan Brand: We have no idea what’s going on but here’s some acid blockers I was never talked to about the root cause ever. So, for me, if you’re seeking a diagnosis, I would just let that attachment go because you really don’t need a term for the symptoms. We just need to figure out what’s going on. So, you mention the diet piece, we hit the gut piece, we hit the—

Dr. Justin Marchegiani: Adrenal and hormone deficiency, too, I think.

Evan Brand: Say that again.

Dr. Justin Marchegiani: We hit the adrenal and hormone piece, too.

Evan Brand: Yeah. Adrenals. That’s very important. So, how should we go about this? I mean, we’ve— we put all the pieces on the table, now how should we arrange this kinda step 1-2-3-4-5? Diet first?

Dr. Justin Marchegiani: So, off the bat, I would say, look at like kind of like your histamine bucket or your stress bucket. Everything goes in that bucket. Some people—it just sucks, they are brought into this world with the poor genetic constitution and their bucket’s smaller. What that means is they just can’t tolerate as much stuff. That means, hey, if they got a little bit of gluten and a little bit of stress, their bucket is full. Some people can have a lot more things. They could have some medications in there, some stress and sleep, some poor food, some nutrient deficiency, and then maybe their symptoms start to increase. Now, again, over time, we naturally have a smaller bucket overtime because our hormones become less restorative the older we get. So we just want to make sure that we know that theirs is bucket mindset and the more we take stressors out of the bucket, we can make a small bucket uhm— we can add more space to it. So someone that’s got a big bucket but is three quarters full, well, if we have a smaller bucket that’s a hundred percent empty, we may create more resiliency for us, even though our bucket, genetically, is smaller. So we have control. We’re not victims. We just got to be honest with ourselves. If we got a small bucket, we just gotta be on point more frequently. So, we do that by working on blood sugar stability, we do that with the baseline Paleo template, that you can work on customizing with your functional medicine doc regarding what that looks like macro wise and whether or not uhm—you have to add an extra digestive support to be able to breakdown the proteins and fats that’s important. Now we can look at the hormones, if there are significant hormone or adrenal issues, we gotta work on it because that helps improve our ability to regulate blood sugar inflammation and stress. And then, we also got to look at our hormones, too. We have significant hormonal imbalances, we have to work on supporting that so we can develop our healthier cycle or healthier anabolic hormones. We could put on muscle and recover. And then, of course, this goes without saying, gut issues. Coz if we have dysbiosis, leaky gut, we have chronic infections like H. pylori or Blasto or Crypto or Entamoeba histolytica or Giardia. Any of these parasites are gonna create leaky gut. They’re gonna create more nutrient deficiencies. And a lot of these nutrient deficiencies are needed to make healthy DAO or HNMT enzymes to break down histamine. And these enzymes, all these nutrients also help make healthy uh— nutrients for a detoxification system as well.

Evan Brand: Well said. So you got to get tested. That’s our philosophy—Test, don’t guess. I mean, you could probably fix maybe 50% of the issue just by working with a good nutritionist, their practitioners are gonna help you dial in the diet, right? Just getting that piece started even if you’re closer to an AIP approach, you are already gonna be eliminating a lot of the problematic foods including alcohol. So if you’re working with a nutritionist, you make it 50% there, but to get fully better, adrenals— test them, we’re gonna run the stool panel, we’re gonna look for infections that way. We’re gonna look for a lot of problems on the organic acids, too. Fungus, yeast Clostridium bacteria, uh— detox problems. I mean, all of that is a factor, so there’s never gonna be just one silver bullet. If somebody tries to sell you my online histamine course and there’s like one silver bullet they’re promoting, I would be skeptical because like any topic we discussed, there’s 20-30 maybe 50 factors that all need to be factored into that pie chart which is the pie chart being your problem. How is that problem broken down? Maybe it’s 50% adrenals for one person, but it could be 5% adrenals for another person. If they’ve got a super positive attitude about it, that could change things, too.

Dr. Justin Marchegiani: Exactly. So we fix the nervous system stimulation, the stress— that’s the diet and lifestyle,  that’s also the adrenals. We fix the gut bacterial imbalance, which could be infections, it could be just low beneficial bacteria. We cut out the high histamine foods. We cut out the histamine blocking, the DAO blocking foods: coffee tea etc. And we try to add lower histamine, paleo foods, in the meantime, which typically are gonna be uhm— low sugar fruits, the citrus-free, typically vegetables are gonna be okay, uh—typically fresh meats are gonna be okay. Healthy fats, maybe minus avocado, are gonna be okay. Uh— avoid the—you know, the aged meats and fermented foods for a period of time. But as we get the gut healed and we fix these issues, we should be able to get better and better and better. And then there also additional supplements we can add in as well. They can make a difference. So in my line, we use one called, Aller Clear, that I formulated that has things like, stinging nettles, it’s got promalin, potassium bicarb uh—these are things that have been used for a long time to help lower histamine naturally. Uhm— big big fan of that. Uhm—let’s see. What else can we do on top of that? I got my list here. Quercetin, like I mentioned, vitamin C, these are in Aller Clear as well to help lower histamine levels naturally. Well I also did a research on that. Grapefruit, seed extract and pycnogenol, which are in these kinda category of league Proantothocyanidin which are these kinda antioxidant bioflavonoid and some of these really good uhm—fruits that can be helpful. We have green tea. Again, it can be a natural antihistamine but can also be a DAO blocker so you got take that with a grain of salt. Uh—magnesium can also be very helpful, stinging nettle can helpful, omega-3 fatty acids uh—can be helpful, uh— some essential oils— peppermint, lavender, lemon can also be helpful. Again, but be careful because some of them are citrus there. You just got to test it out. And of course, a lot of the herbs to help knock down dysbiosis can help in the long run so like the berberines and the goldenseal can also be very helpful as well. So a lot of different alternatives there. Any other comments or concerns, Evan?

Evan Brand: Yeah. I’m guessing some of the medicinal mushrooms can help, too. I’m  not too familiar on the exact mechanism, but I’m assuming things like reishi, cordyceps mushrooms. I’m guessing those may help too depending on how they were grown, of course, uh—would probably make a difference modulating the immune system can be helpful.

Dr. Justin Marchegiani: Absolutely. Is there any other questions or comments you wanna add before we start hitting up some of our listeners questions. I don’t think so. Let’s hit the questions. I’m gonna pull them up, so I can see here, too.

Dr. Justin Marchegiani: Cool. And if you guys uhm—putting comments in the live chat  if you can kinda keep the questions kinda pertinent to the topic, it always helps and again, right now, for answering your question and you like it, give us a thumbs up right now, give us a share, give us a like. We appreciate it. We get really pumped and motivated coz of that.

Evan Brand: Should you—should you interview—uh, not interview—Should you introduce us, I mean I don’t know, maybe we’ve got new people that don’t even know who are these two guys talking about histamine all of a sudden. Should we briefly do that?

Dr. Justin Marchegiani: Yeah. Absolutely.

Evan Brand: Alright. Tell us who you are.

Dr. Justin Marchegiani: Well, I’m Dr. Justin Marchegiani, a functional medicine specialist, a functional medicine Doc and yeah, I see patients all over the world and we work on chronic health issues, from hormone to gut, to detox autoimmune issues and you know, we’re trying to always get to the root cause so that’s me.

Evan Brand: Absolutely.  I’m Evan Brand, functional medicine practitioner and Justin and I been doing this— doing this hustle on the podcast for— for several years. We’ve got hundreds of episodes together and I also work virtually with people via Skype and phone. And we do the live thing because we get comments like this, so let’ dive in.

Dr. Justin Marchegiani: And we’re the real deal. We don’t get a script here. We’re, we’re on-the-fly taking our clinical knowledge and plugging it into you guys, so you guys, the listeners can get healthier which—which is our purpose here.

Evan Brand: Yup.

Dr. Justin Marchegiani: So off the bat, couple things, uhm— I just saw here, Dale made a comment here about toxic mold. So yeah, I’ll connect Dale’s comment to toxic mold. But yeah, mold can definitely be a stressor that can fill up that histamine bucket.

Evan Brand: Yeah.

Dr. Justin Marchegiani: So of course, things that we use to help with mold is number one: good quality or filtration. If the house is really bad with mold, we got to get that remediated maybe even move depending on how bad it is. I never have someone move unless they can—they leave the house for a week or two and they’re like, “Oh my God, all of my issues got so much better!” And again, we gotta be careful because if you’re leaving for a week or two, it may be a vacation where you’re not –

Evan Brand: Yeah.

Dr. Justin Marchegiani: We gotta kinda like control those variables. Maybe you get a hotel room or you go somewhere else and you work outside of the house for a week. But if you notice significant improvement, there could be a mold issue. So air filtration can be good uh—do that little one to two-week test that I mentioned and binders such as modified citrus pectin, zeolite activated charcoal, liposomal glutathione these are all great things to use. A lot of the nutrients to help improve phase I and phase II detoxification. So, in my line, we use Liver Supreme or  antioxidant uhm— Antioxidant Supreme or  we’ll do Detox Aminos. which have a lot of those phase I and phase 2 nutrients. That’s very helpful there.

Evan Brand: Good. I just wanna double comment on that with the recent hurricanes that have hit people in Florida, Georgia, Texas, all the other states affected this mold issue is probably gonna be a lot bigger. A lot of people will probably try to remediate their old mold. Uh—one of my wife’s friend down in Texas posted a picture of her car, they got flooded in Houston. Her entire car, I believe it was leather, may be a fake leather, her entire car was covered in mold that look like a lab experiment, so—

Dr. Justin Marchegiani: Oh my gosh! Sounds terrible.

Evan Brand: So if there’s mold there, please please please don’t try to mitigate that stuff unless you’ve got like proper mask and all that coz you can make yourself sick.

Dr. Justin Marchegiani:  Totally. Couple of questions here. “What are the best herbs for parasites?” Again, I would go look at some of our parasite podcast, we dive into it. Again, in my line, we have GI Clear 1-6 that we use for herbs uhm—to help knock down these infections. Evan has some similar ones in his line as well. So you can check out either Evan site, evanbrand.com or mine at justinhealth.com for more information on that by clicking on the store button.

Evan Brand: Yeah. I’ll hit the second part of the question there. “Are herbs usually enough to beat up parasites?” The answer is, “Yes” We do not prescribe drugs herbs is what we use for bugs and yes bacteria fungus, yeast, parasites. With the right protocol, the right approach, all the other factors, yes, you can successfully get rid of it. I’m a success story. Justin is a success story.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And you know, thousands of people in our belts that we’ve been able to successfully eradicate parasites with herbs.

Dr. Justin Marchegiani: And just to highlight one thing, I think you put in there, but just to make sure any new listeners don’t assume it, we’re also factoring in diet and lifestyle changes into that because that is a massive effect on changing and making the immune system more resilient which has a huge effect on decreasing the chance of reinfection, too.

Evan Brand: Yup, well said, well said. Yeah, you can just take one magic pills, you got to do the hard work, too, which is putting a fork to your plate with good food on it, is organic as much as possible.

Dr. Justin Marchegiani: Totally. 100%. And then, again, some people here talking about H. pylori and SIBO and eradicating H. pylori, uh—they still have stomach issues. So I’ll connect this persons question to the issue. But if you have SIBO and H. Pylori, does that go into your histamine bucket? Yes. So these type of critters and infections can increase that histamine bucket which can create more histamine reactions like Evan and I talked earlier and the breathing issues and the burping constantly, yep. Those are all symptoms of that and that can drive histamine problem. So we got to get to the cause of those infections and again, I refer you back to our H. pylori or SIBO podcast where we spent a full hour talking about that one topic.

Evan Brand: Yup. Well said. Get that test to get that treated. Rosalin, she has itchy skin, scalp. “Is that a symptom of too much histamine in the body always itchy?” What would you say? Sounds like probably.

Dr. Justin Marchegiani:  It could be a histamine issue, it could also be just a fungal issue, too. Seborrheic dermatitis is what affects scalp like that or a.k.a. dandruff and that can be fungal in nature. So I would just look at just the whole gut biome imbalance and/or histamine as a byproduct of that, right? Remember I gave you the a hammer and the thumb analogy, right? The— the histamine is just the collateral damage caused by the— the hammer, right? That’s kinda the whole idea. But, yes, it could definitely be— be part of it but more than likely, not the whole thing.

Evan Brand: Yeah. Kelly had a question, “Thoughts on the Biome test worth the money?” So Biome is a pretty new company who’s running stool testing. I met the guy who created the test. I’ve had a few clients who’ve had that run and they sent it to me. And the readout is— is terrible. I hope they improve on it, but currently, I’ve had a few clients send me their readouts, it’s crap. There’s a bunch of information but there’s no real action.

Dr. Justin Marchegiani:  Not  actionable, right?

Evan Brand: Yeah. It’s not actionable at all. It’s just too much data. So, Kelly, I do not use and Justin. Neither of us use the Biome test. We use more functional test that are available through practitioners. Which I like the idea Biome give people the power to get their own testing, but we still are gonna use other companies like the G.I. MAP on our clients.

Dr. Justin Marchegiani:  Exactly. But the biggest issue is like you get companies that are trying to give you like more information, they’re trying to like dazzle you with all this information, but then you sit back and you’re like, “What the hell can I actually do with it?”

Evan Brand: Yup.

Dr. Justin Marchegiani: What lifestyle change? What diet change? What supplement? What can I eradicate? What can I support or balance based on this information that will help the patient get better? That’s always the question. And the second question is, well does this test allow me to leverage my patient to make an action to allow them to get healthier? And if I don’t get one or two—if I don’t get an answer for one, primarily maybe two, then it just—it becomes not worth it. Kind of you know, glittery, you know, it’s very like, it’s kinda like glittery and flashy and like, “Ooh, look at this!” but it doesn’t really do much to me.

Evan: Yup. Should we get James’ question.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Yeah. So James put friends nine-year-old sons on a new drug, which I looked it up here, Spinraza for spinal muscular atrophy. And it’s a brand-new drug looks like December 2016, it was the first drug approved for this disorder. Now  he’s having swollen lips and hives. Any suggestions will DAO help enzymes? That’s a hard one. Coz who knows if that’s a side effect of the drug or is that some type histamine issue.

Dr. Justin Marchegiani: Yeah. Number one, the kids—Again I don’t know enough about this patient. So this is, take it with a grain of salt, this is a medical—medical uh—you know, uhm—advice. This is just me kinda talking here. So off the bat, kids notoriously have the worst, freaking diets in the world, okay? Especially if they go to school and they’re eating the school lunch and they trade in with their kids. They eat like crap. So number one, clean up the diet. And again, it’s hard because if you’re a parent who’s not eating healthy then it’s your house is full of crap. So first thing is the parent, get all the crap out of your house, create a really good environment, have really healthy snacks, get all of the crap out. So  get on the Paleo template to start. Do that for at least a few weeks to a month. That may fix so many of the issues, but in the meantime, yeah, can you had add  in enzymes like DAO can maybe hard to get them, but can you add in regular digestive enzymes and HCl, yes. Can you add in things like stinging nettle and bromolein and an acetylcysteine and all of the nutrients that I mentioned, yes, you can. So I would definitely add in all those histamine nutrients. Uhm— I would try maybe be going lower histamine, kind of a Paleo template and really get the diet a hundred percent and make sure they’re able to digest their food. HCl enzymes, all of those really good things and that’s a great starting point and then from there, if that still not helping, our only getting part of the way there, you want to really get a functional medicine doc to look deeper at what’s happening with the gut and things.

Evan Brand: Yeah. Well said. That was what—my next thing I was gonna say I’ve seen uh— little girls as young as three and little boys four, five years old with massive gut infections, parasites, and H. pylori and the rest of it. So it’s very possible that that’s going on in the gut depending on the history and use of antibiotics in the kid and things like that.

Dr. Justin Marchegiani: Exactly. Patient here— my w— My mom has been diagnosed with lichen sclerosis, that’s an autoimmune condition that affects the skin. I’ve seen a handful of patients after that cream after cream the probably referring to hydrocortisone, a corticosteroid cream. It gets worse, any tips regarding the root cause of this? Yes. Autoimmune. Get the autoimmune stuff dialed in. I’ll use some stem cell types of creams like J Bio Serum, it’s one of the nice sell that I sell it works great. It’s got some stem cells in it, but you gotta make the diet and lifestyle change. Autoimmune template to start with and then dig in with all the functional medicine principles, next. One of the symptoms of histamine tolerance all the things that we mentioned earlier, from swelling to flushing to headaches to rashes. Anything you wanna add there, Evan?

Evan Brand: Yeah. Fast pulse or a rapid heartbeat. I’ve had women say they eat the food and then their heart starts racing. So could be mood issues, could be physical changes as well.

Dr. Justin Marchegiani: Yeah. And the best way to test for histamine issues, in my opinion, is I just look at people symptoms and I connect them to higher histamine foods and we just pull those foods down a little bit and if their symptoms get better, then we know. I think for me the telltale sign for histamine issues, fermented foods and citrus fruits.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Those are the big telltale for me. Coz they’re relatively healthy foods. No one’s gonna say like, “Oh, eating a grapefruit is bad.” You know having some low sugar Kombucha or you know some sauerkraut is bad. It’s relatively good but if you’re –if we’re doing that history and we see symptoms of those food, then we’re like, “Ooh, there probably is a histamine issue.”

Evan Brand: Yeah. Well said. See, what else we got here. I’ll read a couple off here for you. “Does everyone have some degree of histamine tolerance, don’t think I have histamine problems but not sure.” Well, if you say everyone— the average person is very unhealthy. Autoimmune diseases ramp it, the standard American diet which is the same in Australia, the same in Europe, the same and most developed countries are following kind of a standard American diet— processed grains, sugars, conventional pasteurized dairy, meats that are not organic, they contain hormones and antibiotics. So, yes, most of people are taking Ibuprofen and over-the-counter drugs, they’re taking steroids and doing in antibiotics. They’re getting them in the diet. They’re doing acid blocking drugs, they’re not sleeping well, they’re addicted to their smart phones. So, yes, so many people have things in their bucket. Then, yes, I would say everyone has a degree. Now, kind of our tribe that Justin and I are building of you know, healthy people that are doing as many right things as possible, they’re probably gonna have a less risk of—of histamine intolerance.

Dr. Justin Marchegiani:  Totally. Hundred percent. Makes sense. And how about the bone broth stuff? I mean, I see, you know, I see uhm— lots of people with issue with bone broth and it kinda falls in and around the fermented food issue, right? If you’re having issues fermented foods or things that are slowly cooked, like bone broth, that can increase histamine and that can create a problems. So, again, we may hold off on the bone broth or cook it in a way where it’s cooked shorter. What kind of preparations for bone broth do you do to help lessen it? I know there are some out there.

Evan Brand: Well, I’m spoiled. I haven’t been making it because I’ve been using Kettle & Fire Bone broth that they sent me, so I literally does have to throw it in a in a pot and heat it up. I’ve been fine. I know they slow simmer or slow cook theirs for like 48 something hours like it’s an extremely long simmer time. So I don’t know how that would affect somebody that they were sensitive. But for me, I feel quite well with that. I don’t have any symptoms.

Dr. Justin Marchegiani: Yeah.

Evan Brand: I don’t know. I haven’t had to modified it at all.

Dr. Justin Marchegiani: Yeah. So a couple, you can skim off the scum of the top of the bone broth. You can skim that out. Uh—it may be helpful, you can also do just the shorter brew maybe an 8-12 hour one. Uhm—that can be good. You can also just try buying some maybe your higher-quality or they may have a way of you know, producing it that produces low histamine like the Kettle & Fire. So that could be some good options. But again, if you have a food that we consider to be healthy like bone broth or Kombucha or fermented foods and you can’t respond to it, you can always put that food aside. That’s kind of like that’s like you’re free-histamine test, right?

Evan Brand: Yup.

Dr. Justin Marchegiani: So you can work on the gut. You can work on a lot of these hormone and diet things. And then you can add that thing as your free test add back in the future and that’s a good objective marker to see how you’re doing with your gut. And if it’s starting to heal, you may be able to handle more of that yet.

Evan Brand: Yup. Well said.

Dr. Justin Marchegiani: I believe my link should still be active Kettle & Fire sponsored my show for a while. They’re not anymore but they should still be giving people 20% discount so you can try it. If you do, evanbrand.com/chicken you should be able to get 20% off— so try it out. I think they pay me like a buck if you buy some, but that’s good bone broth and definitely—

Dr. Justin Marchegiani: We’ll support the cause. I know the products—only products that we ever mentioned on our shows are things you believe in. So again, you guys gotta know that we’re coming from a place of authenticity. So if you want to support us and we reference something, just know that it’s got to go to the filter of actually being a high-quality product and we actually have to use it on ourselves and our friends and family for us to recommend it.

Evan Brand: Yup.

Dr. Justin Marchegiani: We appreciate that support.

Evan Brand: Another question here. “What herbs do you suggest for fungal issues?” Once again, I’m gonna say it depends. And I know Justin would say the same thing because we’re gonna make our protocols based on what you’re up against. So if it’s bacteria plus fungus plus yeast plus parasite, that’s gonna be far far more heavy hitting protocol. If it’s just fungus by itself, which is not too common, because most people have a lot of issues together, you may be able to get away with some garlic or some oregano or like Justin mentioned earlier, Berberi or the barberry or the—

 Dr. Justin Marchegiani: Yup. Berberines.

Evan Brand: Berberines. That whole can be great and we’ve got several formulas if you just stalk our stores a bit look on justinhealth and look into his categories and you can check out mine, too. We’ve got many, many different combinations of herbs. Could you go and technically just buy a couple herbs and just you know, shoot a shotgun approach and maybe get success, yes. But I would of course, advise you to get tested because if you have fungal issues, you probably have other issues, too.

Dr. Justin Marchegiani: Yeah. And here’s one like clinical pearl that I’ve kinda find over the years. I’ll throw it out there for everyone listening. How I know fungal issues are more of an issue for— for some people than others, is number one, we’ll see the fungus on a stool test, which will be helpful. We can see either multiple kinds of yeast or fungus where it’s Geotrichum, Microsporidia, Candida, etc. We’ll see different kinds of species. But also on a organic acid test, we’ll see the uhm— D-arabinose, which is a metabolite of Candida but that also kinda means it’s gone systemic. It’s gone more more systemic coming up the urine. So if we see something like the D-arabinose is more of a systemic marker in the urine and we see in the gut, then we know that fungal issue is—is a lot deeper. Now a lot of fungal issues tend to be driven by other issues like H. pylori, other parasites are bigger but some people just gonna have a rip-roaring fungal infection. We’ll see it systemically via the organics as well as on the gut, too.

Evan Brand: Let me ask you this. I mean let’s say you see somebody with a really, really gross fungus fingernail like it look like their fingernails about to falloff because it’s so infected. Would you assume that person has got a massive amount of fungus in the gut and it’s manifesting on the nail on the—on the fingernail?

Dr. Justin Marchegiani: To a certain degree, I would say that’s a good, you know, you can’t hurt yourself faulting that, coming to that conclusion. But again, if you knock out some gut stuff, it can be hard for those herbs and for your immune system to get all the weight at that peripheral tip of that nail to knock out the infection. So sometimes we got topically hit things coz they just got to travel a long way so we’ll either topically hit our herbs there or we’ll uhm—have to do some kind of a soak to hit it as well. Even if we were to address the gut, it may not be enough to make its way down there.

Evan Brand: Coz I’ve seen that. I remember it was a cashier or somewhere, I saw a guy with his finger like his index finger, the nail was literally about the come off and it was completely—

Dr. Justin Marchegiani: There are different degrees, right? There’s like, “Oh, I had a slight fungal nail and I knocked it out with some oregano and a soak and just a few—in a few weeks.” There’s somewhere it’s like nail is incredibly like sclerotic and—

Evan Brand: It was extreme, yeah.

Dr. Justin Marchegiani: Almost falling off and then like totally dis_ that’s like the highest degree. I mean it’s just like, “Oh, it’s a little bit rough and then it’s got a slight yellowish hue.”

Evan Brand: No. I’m talking when it was like—it look like if you flicked it, it would fly off.

Dr. Justin Marchegiani: That’s one of the extreme.  And then the other extreme is maybe– is a light, it’s kinda like a little bit sclerotic like it’s rough.

Evan Brand: Yeah.

Dr. Justin Marchegiani: And if you were to file it, it would get smooth but it would grow out of the bottom again rough. That’s how you know it’s fungal. And typically it’s slightly yellowed. And again, it can go really dark and brown, like dark yellow brown the longer it’s there.

Evan Brand: So what is that? When is that extreme? I mean how in the world would that happen? What sets the stage for that since we talked about—

Dr. Justin Marchegiani: Just chronicity. It’s just deeper and deeper and deeper and deeper into that nail bed.

Evan Brand: Yeah. Wow! Last question here: “What does it mean if a rash shows up only on the legs and not other parts of the body?”

Dr. Justin Marchegiani:  I have no idea. Uhm—again typically the body’s just gonna push stuff out. And again, if things are in the body systemically, where or why the body pushes it out there, beats me. Maybe that’s a stronger area for the body to push it out, hard to say. Again, as things get worse and worse, problems tend to be more systemic, so I wouldn’t worry about why it’s there. Uh the fact that it’s in a local spot is better. I would just want to make sure there’s nothing constant— contact dermatitis issue where things are in contact in that spot. And when nothing is contacting, I wouldn’t worry about it. We’re treating the body systemically as a whole. We’re really work on lymphatics and the detox so everything will get better.

Evan Brand: Yeah. Well said. And I mean—in a rash in the leg, that could be so generic. I mean, that could be something from your skincare products. That could literally be allergy to parabens or something. My wife—

Dr. Justin Marchegiani: A contact dermatitis issue where something is actually touching it.

Evan Brand: Right. Yeah. My wife she had a reaction on her legs and it had nothing to do with diet or histamine or anything. It was just uh—uh she had a sample of the skincare product and it must had some ingredient in it that we didn’t know about and she had a rash on her leg. So don’t—maybe don’t freak out, don’t think too deeply. It could be something that simple.

Dr. Justin Marchegiani: Yeah. And my baby just had some baby acne. My wife is freaking about it a little bit. But it’s just you know, he’s just metabolizing her hormones. So he’s getting over it pretty fast uh— which is good. But again, things happen and if it’s a contact issue like control all the vectors of what’s going on your skin. And then second is like, what’s in your body and just try to decrease inflammation.

Evan Brand: Yup. We got uh—you got time for one or two more?

Dr. Justin Marchegiani: Sure. Let’s do it.

Evan Brand: Alright. James he said, he’s not allergic to nuts and seeds but every time he eats peanut butter, he always gets a fungal rash around his glute region.

Dr. Justin Marchegiani: Don’t touch peanut butter, man. I mean it’s known to be higher in aflatoxin, it’s a legume as well. So that could be some gut-irritating stuff in it. Stay away from that. Switch over to high-quality almond butter instead and let us know how that works.

Evan Brand: Yeah. There’s a brand I use—what is it? Cadia. C-A-D-I-A. It’s like the only organic almond butter I found that’s less than 20 bucks a jar.

Dr. Justin Marchegiani: I actually created my own brand called Justin’s. You’ve seen that brand at Whole Foods?

Evan Brand: I did. Good job!

Dr. Justin Marchegiani: Nah, I’m just kidding. It’s convenient to say it, but, no. Not my brand.

 I won’t take credit for it. But I do like Justin’s. Uh—I will do that a little bit sometimes. And I do like just the whole food 365. I’ll get the organic. It’s also a cool one. Its’ really expensive! It’s called, NuttZo, in an upside down container so like the lid is on the  bottom and it’s upside down kinda thing. That’s kinda cool. Really expensive, but it’s really a nice treat.

Evan Brand: Here’s another question. Uh—little bit off-subject. How is holy basil an adaptogen for stress?” Uh—we’ve done—I could go so long on this.

Dr. Justin Marchegiani: Yeah.

Evan Brand: That I’ll have to shut myself up right now. You just have to check out our other episodes on adaptogens  because I love them and Holy basil, __rhodiola, ashwagandha, all the ones you mentioned.

Dr. Justin Marchegiani: Good.

Evan Brand: We do use all those. They’re great.

Dr. Justin Marchegiani: Yup. I think it’s good. It’s good to kinda rotate through some or use a combination to use them individually and have a rotation to it. I think that’s great. Evan Brand: Yeah. “Is water sounding in ears related to histamine?”

Dr. Justin Marchegiani: The first thing I would look at are just food allergens in general. Uh– especially mucus-producing food, so like dairy and things coz anytime you get more mucus that could go in the ear and that can create issues. Just gluten and inflammatory foods to begin with. So, yeah. Definitely kinda hit that overall  Paleo template, you’ll hit a lot of those things out.

Evan Brand: I think that’s it. We should probably wrap it up. We’re gonna turn into a pumpkin here.

Dr. Justin Marchegiani: I know.

Evan Brand: If there’s any last questions please ask us.

Dr. Justin Marchegiani: How much salt did you ingest for every liter of water you drink replenish lost—I mean, I would just do half a teaspoon to a teaspoon twice a day of high quality mineral base salt. So like my favorites, Real Salt, or you can do Celtic, or Himalayan, just really good minerals that you’re gonna put back into your body. I like that.

Evan Brand: Yeah. I saw a new study about sea salt. I posted it up—I think I put it up on my twitter account where all the sea salt from US and Europe was contaminated with micro particles of plastic and so I’d support your idea of using the real salt which is gonna be an inland sea as opposed to the ocean sea salt that’s contaminated. Dr. J, do you think Tom Brady is on a low histamine diet?

Dr. Justin Marchegiani: Well, let’s breakdown Tom Brady’s diet. He’s eats 20% meat. There’s a lot of means out there. If Tom Brady goes vegan, no—you’re not vegan if 20% of what you eat is meat—not even close. But, as a qualifier there his meats are organic and grass-fed, so there’s really good quality meats. He avoids nightshades, tomatoes, potatoes, eggplants, peppers. He eats lots of vegetables. He eats very little starch. He eats a little bit of fruit. So I would say relatively speaking, yeah. I mean, his kinda thing is, “Oh, I’m eating acid alkaline kinda thing”, right? That may be the result of—that may be what he thinks he’s doing, but my thing is he’s really just doing an anti-inflammatory diet.

Evan Brand: Yup.

Dr. Justin Marchegiani: I’m not worried about acid alkaline. If he is worrying about so being alkaline a hundred percent, he’d avoid the meat, right? But we know that meat has a lot of important nutrients and it’s balance the meat with a lot of the veggies that are very alkaline. I don’t worry about that so much. Most of the acid your body’s gonna get is from inflammation. Inflammation is like 1000 times more acidic than actually eating an acid-base food. So I’m more worried about the food’s inflammatory qualities that I am about whether it’s acid or alkaline. But, again, grains are 10 times more acidic than meat. So if I can leverage that conversation or that idea with the patient, I’ll say, “Hey, if you really wanna be more alkaline, at least meat’s 10 times less acidic than grains.

Evan Brand: Well said.

Dr. Justin Marchegiani: I would think he would be indirectly not his goal but again, anyone that’s on anti-inflammatory diet indirectly, would be lower histamine outside it may be citrus and fermented foods and such.

Evan Brand: Yup. Well said. Well, we’ll wrap this thing up. We hope you enjoy it. If you have more questions, more ideas, more things that you want to hear us cover in terms of topics, reach out. We both got contact forms on our website. Send as an email.

Dr. Justin Marchegiani: Subscribe. We appreciate it. Give us a share, give us a thumbs up.

Evan Brand: Yeah. Justin— Justin’s over 30,000 on the YouTube, man. So great job! Keep it up. Hit the subscribe button so that we can keep pushing up this content in helping you guys achieve the most optimal health on the planet to help us get more people healthy we really appreciate health on the planet.

Dr. Justin Marchegiani: Help us get more people healthy. We really appreciate it. Healthy people make healthy decisions. They’re better parents, they’re better employees they’re better bosses, they’re better everything, so—

Evan Brand: Yeah. I saw Mark Hyman he was talking about autoimmunity and how it’s twice or even up to 10 times more expensive to take care of a sick patient with autoimmune disease and so we guys want you to be healthy because to save our population from collapsing. We’re kind of in the midst of healthcare collapse. Basically, the health of society falling apart. We’re trying to make a healthy dent in the universe by helping you guys. So thanks for the feedback. It means a lot to us.

Dr. Justin Marchegiani: Love it, Evan. Alright, man. Great chat today. I appreciate it.

Evan Brand: Take care. Bye.

Dr. Justin Marchegiani: You too, take care.

 


 

References:

https://justinhealth.com/products/aller-clear/

https://justinhealth.com/products/liver-supreme/

https://justinhealth.com/products/antioxidant-supreme/

https://justinhealth.com/products/detox-aminos/

https://justinhealth.com/products/gi-clear-1/gi-clear-1-2/

https://justinhealth.com/products/j-bio-serum/

https://www.kettleandfire.com/

http://mycadia.com/

https://www.nuttzo.com/

https://realsalt.com/

http://www.celticseasalt.com/

https://www.seasalt.com/gourmet-salt/himalayan-salt.html

 

 

Tips for a Healthy Pregnancy – Dr. Justin Live Podcast #153

Dr. Justin Marchegiani and Evan Brand dive into a discussion about having a healthy pregnancy. Gain some valuable information as they talk about nutrition, diet and lab tests before and during pregnancy.

Learn how different factors such as estrogen dominance, autoimmune  diseases, toxic substances and nutrition issues affect fertility. Find out about In Vitro Fertilization (IVF), understand the reason why some people choose this option of conceiving and discover some of the natural solutions and recommendations to health-related and nutrition issues that hinder people from having a natural and healthy pregnancy.

 Tips For A Healthy Pregnancy

In this episode, we cover:

11:08   Factors affecting fertility 

21:36   Food sensitivities and miscarriages

25:00   In Vitro Fertilization

35:14   Blood sugar in pregnancy

36:08   Thyroid issues in pregnancy

 

 

Dr. Justin Marchegiani YouTube channel

 


 

 

Dr. Justin Marchegiani: And we are live here. Dr. J in the house with Evan. Evan, how you doin’ man? How’s your day goin?

Evan Brand: Life is good. How are you doin’?

Dr. Justin Marchegiani: Very good. The first podcast officially as a dad—feels really good and really rewarding. Little bit sleep deprived and my wife is taking the brunt of it, but I’m doing my best to uh— be a supporting about— a very supportive husband providing all the nutrition she needs, cooking all her meals. We got a little fridge right outside the baby’s room put upstairs. And I got—it’s stuffed with bone broth, Kombucha, sparkling mineral water, uh— filtered water electrolyte and hence, she’s got a handful of meals. Paleo meals I already prepared. She’s got some really good healthy snacks. She gets some collagen smoothies and shakes up there, so I got her like stock up some. My goal is to try to feed the baby uh—kinda proxy, right? getting all the nutrition she needs and therefore, she could take it in as easy as possible and then provide the best nutrition for the baby.

Dr. Justin Marchegiani:  Absolutely, man. Well, congratulations. I’m super happy for you. It’s been a— been a long time coming. When you’re waiting for stuff like this, a day feels like a week and a week feels like a year, so—

Dr. Justin Marchegiani: Yeah. And the baby’s name is Aiden Raymond Marchegiani. And Aiden means little fire, so. The boy— we’re really, really stoked to have him and we’re just trying to provide him as much nutrition as possible. He was in the NICU for a day and a quarter. Maybe two days, let’s just say. He had a slight collapsed lung birth. He was doing great and then as soon as the cord was cut, which we’re trying to delay clamping as much as possible—but it’s a C-section, right, so like you know while the baby’s got the cord attached, you know, mom’s open bleeding, right, so with the weighing out the benefits—

Evan Brand: Ahh..

Dr. Justin Marchegiani: Normally we’d wait ‘til that cord with pulse turn til it’s white. You know, go white and such, which maybe 10 minutes or so. We didn’t quite have that luxury, so, you know, we framed it out with the OB. Had a time we delayed as long as we could, and as soon as that cord was cut, he crashed. His O2 suction levels dropped. They put a  C Pap on him. They got his O2 up; they run a chest x-ray and right after there’s a slight collapsed lung. But in a day and a quarter, day and a half—healed.

Evan Brand: Wow!

Dr. Justin Marchegiani: So he was super, super resilient. And we just—you know, we have to contribute the fact that my wife’s nutrition and sleep and all that stuff was just really great during her pregnancy. And that probably attributed to his resilience.

Evan Brand: I’m glad it all worked out.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And you guys are home safe.

Dr. Justin Marchegiani: Yeah. I mean the NICU docs were pretty—I think very shocked. They were telling me if we could be in there up to three weeks. And she was like, two days.

Evan Brand: Wow!

Dr. Justin Marchegiani: So it was pretty great to see that.

Evan Brand: So the people are probably like, “what happened?” you know, “You guys talk so much about holistic self why a C-section? Do you care to elaborate some of that?”

Dr. Justin Marchegiani: Oh, yeah. Let’s talk about that. I’ve talked about it in other podcast, in other episode, but people may not listen everything, so will kinda make it so it all connects. My wife had a large fibroid removed about a year and a half ago— about the size of a baby’s head. There’s a very big fibroid. She’d taken birth control pills for 15 years, you know, in her late teens into her early 30s.

Evan Brand: You think that might have caused it?

Dr. Justin Marchegiani: I think that’s a contributing factor if you listen to my podcast with Dr. Horwitz, he’s a fibroid expert and he says that you know, estrogen dominant states can definitely drive fibroid growth. There’s not a lot of research on it. I don’t think there’s gonna – there’s gonna be a lot of motivation to do a lot of research on it, but we know estrogen dominance can cause things like fibroids to happen. And then the question is, what can drive estrogen dominance, right? We know stress drives it. we know, you know, estrogens drive it. We know phyto estrogens, right? We know low progesterone states can drive it. We also know birth control pills can drive estrogen dominance, right? So it’s the milieu, the hormonal milieu. And also, just not getting pregnant. Getting pregnant later in life can also drive it because when you get pregnant, you’re really driving a progesterone dominance state. And then breast feeding, right, you’re keeping progesterone levels really high, too. So my wife got pregnant at age 40 and we decided that to get the fibroid removed just because one, it was so big and number two, we just have a smaller fertility window.

Evan Brand: Yeah.

Dr. Justin Marchegiani: The fertility window’s a lot smaller and we can get that fibroid removed we can get pregnant like that. And again, her hormones are that of a young 30 year old woman. So we had done work with her, helping her hormones, PMS, all that was really good. Her hormones were that of someone 10 years younger. She just had this big fibroid which acted like an IUD, right?

Evan Brand: Wow!

Dr. Justin Marchegiani: Intra Uterine Device which basically just— imagine this fibroid there just sucking up blood flow so that when an egg comes in, it’s not gonna be able to stick because there’s not enough blood flow to sustain it, right? So soon as that fiber was removed, we get pregnant. Two weeks after it was removed. And the doctor was like, “Okay, you know, you can try.” But he’s kinda not expecting much. But as soon as we tried the first time, we got pregnant. And yeah, we actually uhm— lost that baby but it was a blighted ovum. So none—is really a baby. There was no like heartbeat or anything, which is the sack but we lost it which was tough, but you know, we just kind of attribute it to the fact that she’s went to a major surgery, right? She was under general anesthesia. She’s on pain meds. Probably wasn’t the best time to try to get pregnant. We only did because the doctor said it would be okay. But as soon as you know, that— the hCG dropped and she got her period back, we tried again and then we got pregnant. So uh—that’s the baby we had now, Aiden, so, we’re very stoked. So the reason why we had to do the C-section, coming back, is because the incision was along the posterior section of the uterus which had kinda weaken the uterus which had her increase her chance of a uterine rupture. And because of that increased chance of a uterine rupture—the uterus rupture is you know baby and mom can die. So they had to pull the baby out four weeks sooner week 36 just to ensure that uterus wouldn’t rupture. It’s only a 1% chance but you know we spoke to midwives and OBs and no one recommended— no one would even do a natural birth.

Evan Brand: Oh, wow!

Dr. Justin Marchegiani: Just because of the liability was so high. But I was able to watch the whole entire surgery. And I literally—you know, they her uterus in her hand and I was like, “Hey, can you look at the backside?” This is after the baby was born. They turn at the backside. “How’s the posterior incision? Let’s look at it.” And she was like lookin’ at it, “I can’t even see an incision.” So the uterus healed up so strong and what I attribute that to is I have my wife on the Tru Collagen every day. She was doing about 30 g of collagen every single day. And I know that those collagen, amino acids had to— made a huge difference in helping to provide extra building blocks to the— to her uterus to heal up. But they couldn’t even see an incision to the back.

Evan Brand: Well, also, you mentioned she had no stretch marks, too, which is a pretty remarkable testimonial.

Dr. Justin Marchegiani: Yeah. She had no stretch marks. Again, the baby came four weeks early so some women will say, “the stretchmark comes that last 2 to 4 weeks” But again, in my opinion a lot of people are getting a lot of their protein from muscle meats which is, you know, still good. But, again, collagen is gonna be connective tissue protein. That’s ligaments, tendons, cartilage, hide skin, right? So you’re getting a lot more building blocks that are gonna help the connective tissue and the skin. And a lot of what’s happening with the stretching of the skin and the fascia and all that tissue is gonna be connective tissue-based. So I think that providing one, lots of healthy fats and two, providing all the extra collagen peptides really help number one, her uterus heal, number two help the skin heal and number three, I also think it will help uhm—the breast. A lot of women, their breast tissue kinda gets flattened and kind of, you know, really just kind of uhm—just flattened a bit. Maybe the breast will start sagging and hanging and such after a long time of breastfeeding. I think the connective tissue support will also help the integrity of the breast tissue as well.

Evan Brand: Ahh.. That’s interesting.t I believe that there’s probably gonna be benefits. I mean, I wonder if we compared standard American women compared to hunter-gatherer women. Like what was the difference in their skin quality probably huge difference coz the hunter gatherers eating the marrow and the collagen and the bones and doing more stuff than typical women do.

Dr. Justin Marchegiani: Yeah. I mean if you look at some of the anthropomorphic kind of research, like they talk about literally taking the organs and like harvesting them. And the organs would be like literally given to the women that were fertile, that were trying to get pregnant because they knew the organs were incredibly, you know, nutrient dense. And there’s also research to these women like would literally give birth uhm— that— that day and be back out on the field later on that day or that next day working.

Evan Brand: Wow!

Dr. Justin Marchegiani:  It’s crazy, right? I mean they probably had a lot less stress in her life, too, right?

Evan Brand: True.

Dr. Justin Marchegiani: Very, very little stress, but still uhm— it’s amazing what the body is capable of doing. So that is kinda like my back stories that just kinda summarizing uh—history of fibroid and there are natural ways to reduce fibroids and I’ve seen them reduced and it help with those kind of situation in the past. We just—we’re dealing with the time window, right? And if a woman’s like in her 20s or early 30s and has a few years, hey, that may be a good thing to try, but in my opinion, uhm— you know, if you’re up against a pregnancy window, getting it surgically removed is good. But if you listen to my interview Dr. Horwitz he said women that he’s removed the same fibroid three times. So what does that tell you? That just because you remove a fibroid, that does not fix the underlying issue of why that fibroid is growing anyway, right?

Evan Brand: That makes sense. So the birth control, for example, could’ve been one thing. There gotta be an insulin components, my guess.

Dr. Justin Marchegiani: It’s probably an insulin component, too, for sure. There’s probably toxicity component too, right? Coz a lot of toxins are estrogenic compound.

Evan Brand: Yup. Right.

Dr. Justin Marchegiani: So there’s some of that. So we’re trying to do our best to support all that and again one, of the protocols will be doing is using some systemic-based enzymes or peptidase etc. to really help. She has one tiny fibroid still there. It’s in around the fallopian tube. The fallopian tubes is so patent. So it’s still open and I literally was like, you know, you’re yellin’ at the OB, “Hey, can you check out her left fallopian tube. How does it look?” She’s like, “Oh, that little, tiny fibroid—like you know, half of the fingernail, still there in the fallopian tube, but it’s not growing. So, you know, our goal is we’re gonna try to work on dissolving that one naturally uhm—you know, over the next few years.

Evan Brand: That’s amazing. So when it had to be cut out, you can just go in there with tweezers and yank it off or something, it’s not that easy.

Dr. Justin Marchegiani: Yeah. The fallopian tube’s kinda—you could, but you’d compromise the fallopian tube.

Evan Brand: Oh, wow!

Dr. Justin Marchegiani: And the fallopian tube is still open, so it doesn’t make sense. She had one little, tiny fibroid actually uhm— there at the incision site, where they cut the uterus to deliver the baby. So actually, she got two for one. They removed that little baby fibroid at the incision.

Evan Brand: Wow! Did you see that? What did it look like?

Dr. Justin Marchegiani: I mean, it’s just—I got pictures of it, but uh—yeah, it’s just like a little, like mini golf ball.

Evan Brand: Really? And what—what’s the texture of it?

Dr. Justin Marchegiani:  It’s kinda like uh—fibrous.

Evan Brand: Oh, that makes sense.

Dr. Justin Marchegiani: So like uhm—I’m trying to think of a consistency— it’s just— it’s dense but it’s a slight bit of squishiness to it, but it’s still—

Evan Brand: Yeah. That makes sense. That’s amazing.

Dr. Justin Marchegiani: Yeah. Almost like a tennis ball-like consistency.

Evan Brand: Yup.

Dr. Justin Marchegiani: But it’s still pretty firm.

Evan Brand: Yup, I understand.

Dr. Justin Marchegiani: So that’s kinda like the back— the back history on myself and my wife but when you’re looking at fertility, right, we look at a couple of things. Number one: How are the hormones, right? How are the hormones? Number two: How—how are the pipes, right? Are the fallopian tubes open? How’s the endometrial lining? Is it—is it okay for something to be able to, you know, implant there. And then number three: is we look at the dad.

Evan Brand: Exactly.

Dr. Justin Marchegiani: How’s the sperm count, motility, morphology. I was actually, really has no problem at that moment—that I was rock solid on all those numbers. So I felt very, very good about that.

Evan Brand: See that’s the problem, you know, You and I worked with so many— so many women. Primarily, men aren’t coming to us for fertility issues, but they have to come on board because it’s part of the equation. And a lot of these women that we speak with, the men, they just have a terrible diet. So we may put the mom or the future mom on AIP, but then the dad is still eating ice cream and pizza. And then they end up at the—in the—what do they call it, the vitro fertilization doctors, who want to spend what? 10-12-15 grand. But they may be unnecessary in most cases if we get the dad straightened out as well.

Dr. Justin Marchegiani:  Exactly. I mean, a lot of times, you know, what’s gonna affect the fertility is number one: having a nutrient poor diet; not having enough high-quality nutrients like zinc and arginine and healthy fats and proteins. And then also uhm— mitochondrial support coz sperm needs mitochondria to move or needs a healthy mitochondrial nutrients to be able to the kind of propel it, so to speak, right? So we have to make sure a lot of the good mitochondrial support there. And then we’re just not putting a bunch of toxins in there, right? Like we’re avoiding the plastics, we’re avoiding the pesticides, the chemicals, the round up, the glyphosate—all these compounds that are not gonna be so good for it.

Evan Brand: Yeah. The endocrine disruptors like you mentioned, like the plastic, so getting men and women off of Tupperware. I guess, by the way, if you haven’t figured out, this topic we’re— we’re talking about fertility today. Since Justin and I are both dads and our wives are both moms. This is a good topic for us. We’ve had first-hand experience on. So this is not theory and there’s also some science behind what we talk about. But that the endocrine disruptors that can cause things like the PCOS, which a lot of women that come to us, they’ve had PCOS. Previously are there—they’re trying to get help in reversing PCOS. That can be a huge, huge hormonal function disruptor that can affect fertility. So we’ve got to get rid of the the plastics. Plastic straws are a big one because your saliva, you know, my opinion, you’re breaking down that plastic a bit and you’re absorbing some of the— the phthalates in the plastic softeners when you’re chewing and using straws as toothpicks, that’s not a good one. Also, you’ve got flooring, too, like vinyl flooring. So if you’re walking barefoot on a vinyl floor, that’s typically gonna have phthalates in it. You’ve also got issues with the men as well. They’re just as susceptible to exposure to phthalates and other type of toxins. You mentioned pesticide so definitely going organic. If someone’s a mom, a lot of times women they’ve already had her first kid but they wanna have another kid and they are coming to you or I would see that a lot, too. You know,  I tell a lot of moms have got to stay away from a lot of the playgrounds because they use the rubber tires, the recycled tire playgrounds and those are very, very toxic and I’ve measured moms with the GPL tox chemical profile test from Great Plains and they’ve got the rubber toxins off the chart. And I say, “where are you playing?” And they say, “Oh, we go to one of those playgrounds with the recycled rubber tires” And that stuff is just super toxic or let’s say the mom has a kid who started sports, my God, I work with the woman last week who lived in London, and her child he was off the charts himself. So we haven’t tested mom yet, but we tested the kid coz we’re working more with him than her. And the kid was off the charts with 2,4-D— the agent orange chemical that they used in Vietnam. And I said you know, “Where are you guys playing?” And she goes, “Oh, he plays soccer” I said, “Is that football or soccer?” Coz she call it football. So is that football football or is that soccer?

Dr. Justin Marchegiani: Right.

Evan Brand: And so she’s on the field with this kid multiple times a week. In the field, just sprayed, I’m sure, pounds and pounds and pounds of glyphosate and 2,4-D

Dr. Justin Marchegiani: Yeah. I mean I kinda go back and forth, what’s worse, right, being on the artificial turf stuff or being on the grass? Coz you know the grass has given a whole bunch of chemicals, right?

Evan Brand: I Know.

Dr. Justin Marchegiani: So I—for me, and again, how many research? I’m just—a lot of what I do is common sense and based clinically.

Evan Brand: Yup.

Dr. Justin Marchegiani: Coz I probably rather be on the synthetic turf grass because at least you know it’s not being spray with round up.

Evan Brand: Yeah.

Dr. Justin Marchegiani: ..and pesticides all the time.

Evan Brand: I know. I don’t think they spray anything. One other thing about men, you know, when we’re talking about fertility for men, sperm quality. Heavy metals is huge. Mercola had an article about infertility where he was talking about how men are much more susceptible to issues in their fertility with heavy metals than eggs. So the eggs in the female were less affected by heavy metals and other pollutants than men. So that’s pretty interesting. A lot of guys have metal amalgams in their mouth. So we may— I’ve not personally had to go that far with any of my clients but what would you say? Would you say that could be a possible step? Does the man have to— may have to get a amalgam removal is done?

Dr. Justin Marchegiani: Yeah. I mean I think that’s definitely an option. If we’re seeing elevations in heavy metals—anytime I have someone a male with fertility issues, once the diet’s good and we’ve eliminated toxin exposure, then it’s about what nutrients can we add to enhance sperm quality, and then what things can we add to enhance detoxification.

Evan Brand: Right.

Dr. Justin Marchegiani: Maybe phase I or phase II detoxifying nutrients and maybe things to help push the heavy metal binding. So again, I’d wanna look at all that and if we’re seeing high levels of metals, and we know Mercury’s there, and then we’re seeing the person also the history of fillings— heavy metal fillings and then we wanna get that removed.

Evan Brand: Tapwater. Gotta have a good clean water that the person is drinking. We talked about the— the phthalates. So the xeno estrogens—coz that’s gonna affect the males.

Dr. Justin Marchegiani: Yeah. So if the male is more like a woman, you know, he’s got a lot of excess breast tissue and things like that, and we can assume, “okay you’ve probably got some estrogen problems” So just like you mentioned about females. Same thing for men, it could be an estrogen dominance problem.

Dr. Justin Marchegiani: Yeah. And we can look at that from two perspectives. I did a video called the “Hormone Switch” I recommend everyone to take a look at that. Will try to put links below for the “Hormone Switch” But when men’s blood sugar’s off, when they start moving into a direction of insulin resistance, they increase this enzyme called aromatase, which causes the hormone to switch. It will cause their testosterone to go more towards estrogen. And we see that quite frequently. And again, one of the best thing get one of the best thing you can do is put on more muscle. That will make you more insulin sensitive. A high intensity training type of regimen where you’re doing like a long, slow movement to get muscle activation or to get HGH, where you’re doing interval stuff. That’s gonna help significantly get the blood sugar under control and get the inflammation under control. A lot of these stuff, we always go back to the foundation coz we know there are people that are new that are listening every day so we don’t want to assume that the foundation is there. And all of our patients that listen, you know, listeners they get that. We kinda feel like a broken recored, but just to emphasize for new listeners.

Evan Brand: Yeah. We wanna get rid of dairy. I mean that’s gonna be huge on the diet piece. We’re talking about or talk about stabilizing blood sugar; we’re getting refined carbs out; were getting sugars out, but dairy, too. You know, depending on what piece of research you look at, that could be 60 to 70% of the estrogens consumed is coming from dairy, especially these cows that are not organic. So for us, the dairy is always gonna come out. Organic veggies are always good come in, organic fats, your nuts, your seeds, your vegetables. Unless the woman has some type of like Hashimoto’s problem which that can complicate things with fertility. Sometimes if there’s a thyroid issue, but let’s just assume that the person can do a good quality butter, can do some nuts, some seeds, maybe a little game meat even. That’d be cool. If we could get the mom eating some—some deer, or some type of game organ meats, or sardines.

Dr. Justin Marchegiani: Yeah.

Evan Brand:..or other home-cooked, home-sourced wild turkey, which we have ton of turkeys here. Those are awesome, too. Unfortunately, it doesn’t seem like local fish is an option here in Kentucky. I was reading the report by the Kentucky Department of Fish and Wildlife. They said that most of the fish are toxic here, unfortunately. With the— with high levels of mercury. So they set for people wanting to get pregnant or pregnant people should avoid the fish, which kinda sucks.

Dr. Justin Marchegiani: Yeah. Actually when it comes to the fish component, uhm—I have an article that I give my patients but really, it comes down to number one: trying to get the wild—you know, the wild Alaskan or like some kind of flash frozen, kinda wild fish, I think is great, is ideal. But it’s looking at the selenium to mercury ratio. Because fish are going to have a little bit mercury. The question is, “Is there enough selenium to combat it?” Because the selenium is the natural chelator of mercury. So just try to choose high selenium to mercury ratio fish. So skip Jack tuna. It’s gonna be the best type of fish off the bat uh—cod, haddock, sole, halibut. Those things are good. I have a good article in my member’s area for my patients. But if you just google like “high selenium to mercury ratio fish” you’ll get a nice list there.

Evan Brand: Uh—cool. I love cod, haddock. Those are awesome. I had something pulled up. I was trying to see I may have lost it, but just mentioning the link between food sensitivities and also miscarriages. Basically what happened is the link between having some type of allergenic reaction, you’ve got the cytokines that are basically suppressing the killer cells.

Dr. Justin Marchegiani: Yup.

Evan Brand: But when the immune system is off, the body can accidentally attack the egg. So basically, long story short, it sounds like just searching, investigating and finding out for food intolerances, which we’re gonna push most people into kind of a Paleo template as the starting place. Probably no grains, but at least no gluten, no dairy as a starting place. Will probably gonna rule a lot of those food intolerances out within the first month.

Dr. Justin Marchegiani: Yeah. Even push to autoimmune shtick as well. I know you kinda talk about a deer. That’s good when you’re doing autoimmune shtick, but I think adding at least back in the ghee and definitely the butter, as long as you can tolerate it, as long as like, there my patients are following the reintroduction protocol, which is adding the food back in over a three-day period. Gently increasing the amount as long as no negative reactions that’s fine coz you know, butter butyric acid’s a 1:6 uhm— carbon fatty acids. So it’s a medium chain triglycerides, so to speak, right? It’s very short chain length. It’s four carbons or six carbons, but it’s a really good fat; it’s a lot of nutrition, a lot of vitamin K which is really, really good for fertility uhm— so that’s uh—excellent fat as long as you can tolerate it, I think that’s great.

Evan Brand: And other bad things, too, like alcohol.

Dr. Justin Marchegiani:  Of course. Like alcohol number one: it’s a toxin. Again, in moderation maybe okay but number two: it gets metabolized to sugar. So if you have a little bit insulin resistance or blood sugar stuff, that can be a stressor. Again there’s ways to hack it by just using higher-quality alcohol and by timing it with protein and a little bit of fat uh—with your meals. It can slow down some of the absorption but you know, for a time period, if you have health issues, cutting it out for a month or two maybe a good idea to start with. And then choosing some of the drier, you know, white wines or drier champagne or Presecco or doing a really clean tequila or really clean vodka. Again, my Dr. J Moscow mules is one of my go-to’s  use with uh—Tito’s vodka and the ginger Kombucha and some lime. Or I just do a really good like Sean Don or like a really good brewed Presecco, very dry. I like the bubbles. Bubbles are uhm—you know the uh— the seltzer or like the CO2 carbonation. The bubbles are actually—there is actually research studies where they increase alcohol absorption with the bubbles. I was reading one study. I was like, “Damn, I love  to be in the study.” Like— you know, 15 years ago when I was in college, they were like, “ Yeah. We had a group of college kids and we gave one group alcohol and one group alcohol with you know carbonation and soda water.” I’m like, “that’s a great study for college.” Right? I know like, yeah, the group that got the carbonation with their alcohol uhm—you know, felt the effects, felt the intoxication effects or the buzz, you know, the so-called buzz effects sooner. So there’s some research with the carbonation in there helping to absorb the alcohol. So what does that mean, right? It means you’re a cheaper date.

Evan Brand: Yup.

Dr. Justin Marchegiani: You— less of it to get that same buzz, which means less toxicity on the liver. So that’s why like add the bubbles in there, that’s better. And you get that with my Dr. J Moscow Mule. Uh—you can do it as well with my Norcal margarita and we just you know, do a little bit of soda water in there when you can also do a really dry Sean Don or brewed Prosecco kinda drink there.

Evan Brand: Perfect. Let’s talk about IVF just for a minute. A lot of people and you know, the in vitro fertilization is like the first step if they are struggling. Diet, lifestyle, stopping smoking, which is insane. My wife had some friends that she’s not friends with them anymore because they’re just there were not good people overall. So we— we cut them out. They were too toxic in many ways.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Emotionally and physically, smoking cigarettes around her when she was pregnant, all sorts of crazy stuff. So we got rid of them.

Dr. Justin Marchegiani: It’s hard for someone to truly be emotionally balanced and healthy if they’re not physically healthy because the mind-body connection is just— it’s so strong, right?

Evan Brand: I know. Uhm—so anyway— but these people that used to be her friends.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: The guy, the dad, they were struggling with years. I think they were in their early 30s. They were struggling for years. They still do not have a child to this day. The guy was drinking beer almost every weekend, daily smoking of cigarettes, Mountain Dew’s. But yet they went to an in vitro fertilization doc and they were gonna spend 10 or 15,000 for the therapy.

Dr. Justin Marchegiani: Yeah.

Evan Brand: It’s just insane. You’re not addressing the root cause.

Dr. Justin Marchegiani: No, you’re not. I mean, typically the first, you know, thing they’re going to do is they’re gonna do some kind of Clomid or FSH stimulating drug. The core goal of that is to increase the eggs, increasing amount of eggs, right? So they’ll do like Clomiphene Citrate or some kinda Clomid and then depending on sperm quality. If the sperm count is low, they may do IUI which is like intrauterine insemination kinda fancy turkey baster.

Evan Brand: Yeah.

Dr. Justin Marchegiani: The sperm up and they may wash it and stuff and pick the best ones and then they’ll inject it right into the uterus. So then there’s no journey of these guys have to— the sperm cells have to make to get up there, right? Coz if they’re a little bit more mitochondrial depleted, or they don’t have good mor—motility, like they’re not moving in the right direction or their shapes not good. They may not be able to make the journey. So the whole idea is to use that uhm—artificial turkey baster. You can get it right there, so their journey is shorter, right? You’re cutting their journey down by 80% and then they’re stimulating the heck out of the eggs. That’s the first step. And the next step is full IVF which is they’re basically giving you drugs like Lupron to shut down your HP AG access, you know, your hypothalamus pituitary axis, And they’re gonna give drugs to stimulate FSH. Uh—they’re gonna give drugs to then manipulate ovulation. And then they’ll probably give some kind of uh—progesterone afterwards to help hold the implantation of the egg. That’s pretty much the cookbook. There are new medication that comes in—Gonal-F, Follistim, Lupron. All these different drugs may be used uhm—but the goal is kinda the same— stimulate, you know, egg production, enhance ovulation, help hold onto uhm— progesterone levels so the eggs stick better.

Evan Brand: Well, I remember seeing a picture. I think it’s a picture of my wife that showed me where this couple had had hundreds of vials— like an entire couch or an entire floor full of vials that were daily injections, I believe, for that whole process. Which this is one: it’s expensive; two: that just doesn’t sound very fun; and three: in a lot of cases, I don’t have any numbers. I’m not gonna make up a number on the spot, but in so many cases, if you just address diet, lifestyle infections, thyroid health, adrenal health, you’re doing the fatty acids like you talked about, the collagens, your zincs and selenium’s, and your natural folate’s, and your vitamin C, and your omega-3’s, it’s like that’s a prescription that’s gonna have far higher success rate and it’s gonna be virtually free because you have to eat to survive. So you’re going to be eating all these good things, anyway.

Dr. Justin Marchegiani: Totally. And we do things like chase tree and tribulus to modulate LH and FSH. So like that will modulate FSH; the tribulus will modulate LH with chase tree. And these are things that help talk—help the brain talk to the end gonads, you know and create stimulate the follicle or help the progesterone, right? So will do that with some herbs. We can always c_  augmentation protocol where we put estrogen—I’m sorry—progesterones in there, right? at certain times of the cycle, day 15-27. We can even add in some uterine supporting herbs like maca, m__, dong quia, alpha alpha, raspberry leaf extract. These are great uterine tonic herbs that really help the blood flow get to the uterus which is good because that uterus— these adequate blood flow to help support that egg when it sticks. So I tell patients think of progesterone as a sticky glue that helps the egg hold, but we need good uterine flow. That’s why my wife and I had a hard time getting pregnant at first because we have this fibroid that was sucking a lot of the angiogenesis out, right, the angiogenesis’ blood flow. So it’s creating a lot of blood flow to the fibroid and not to whatever else was gonna stick there i.e. the egg.

Evan Brand: So did you all have to do herbs? Or did you do herbs or just the diet lifestyle is all you needed?

Dr. Justin Marchegiani: Uh—we had herbs going in the background the whole time.

Evan Brand: Okay.

Dr. Justin Marchegiani: Yeah. We had that the whole time there and uhm— a little bit of progesterone going as well. And again, we just— I measured it, like I want 15 or higher, 20 is ideal. So Iike after she got pregnant, we measured progesterone. We make sure it was adequate. And it was, so we pulled off it.

Evan Brand: And what were you doing? Like drops or—

Dr. Justin Marchegiani: Progesterone drops. Yup. Exactly. So, like typically like a 100 mg is a good starting point once you get pregnant. And again, we just monitor it and it just kept on rocking. And again, if the ACG is high enough, typically the progesterone will be high enough because the hCG is uhm—gonna be produced by you know the follicle and also the placenta will kick in and produce it as well. And that hCG will then jack up the progesterone, too.

Evan Brand: Oh, that’s cool. all that’s cool okay you didn’t you didn’t have to continue, you’re saying?

Dr. Justin Marchegiani: Correct. You know, we didn’t have to. But some women who have lower progesterone, they may have to keep that progesterone going for the first trimester.

Evan Brand: Now is that something you have to get via prescription or are there over-the-counter natural ones you can get?

Dr. Justin Marchegiani: It depends. I mean, I typically give my sublingual one until I can get the fertility OB to write one, just more from a legal standpoint. I rather have the OB write about identical prescription just so, you know, if they’re working with that person that we know it’s covered. But the protocol is gonna be the same and typically will do like an intervaginal uhm— progesterone just so we know it’s getting right to the tissue. It’s—it’s— it’s being released closest to the tissues. So will do that. If we have an option, some OBs that they won’t do it uhm— just because they’re not looking at the progesterone or because a woman doesn’t have a—a history of miscarriage. They’re not gonna even look at it. But I mean, do you really wanna go through a miscarriage then know your at risk to then wait to the next time to do it?

Evan Brand: No joke. Right.

Dr. Justin Marchegiani: Yeah. I rather be monitoring it. And you know, if it’s below 15 or you know, I’m gonna be supplementing with some progesterone to make sure their support there. You can’t go wrong with it. Just make sure you’re using the good-quality progesterone. And again, we’re giving a lot of clinical advice here. And there maybe a lot of people that are just lay people listening. I don’t recommend doing this by yourself if you really want to work with the provider that’s done this a lot, so uhm— you know what’s going on and you wanna have everything looked at. So you want to make sure that we’re supporting the adrenals. Typically when someone’s pregnant, the only thing I’ll keep them on are nutrition, nutrients, whether it’s vitamins, minerals, amino. I’ll typically keep them on probiotics, I’ll keep them on digestive support, HCL enzymes and the only hormone I’ll typically keep them on, when they are pregnant, if it’s necessary “necessary” is the progesterone.

Evan Brand: Yup. Well said. Well that’s the thing. We love talking about adaptogens so much but nobody’s gonna do the research on rhodiola or these other herbs and how they could impact the fetus. So we just, you know, we love those things but we just can’t safely recommend them because we just don’t know.

Dr. Justin Marchegiani:  It’s probably safe, but again, like, think about it, who’s gonna sign up for that study?

Evan Brand: I know.

Dr. Justin Marchegiani: Right. Whose gonna sign up? “Hey, by the way, congrats! You’re pregnant. Hey we’d love to have you sign up for this study where we test these adaptogenic herbs on health and viability”  “Uh—no, I’m good.

Evan Brand: Right. So I mean—some of it we can draw from—from ancient peoples what they’ve used. Like you mentioned the chase tree which has been used in extreme long time. So a lot of it, we’ve probably already lost due to just modern life. We’ve lost touch with our hunter-gatherers, what herbs and plants and trees and stuff that they use during pregnancy, unfortunately. But like you said, diet lifestyle, foundations, HCL, enzymes, probiotics, fish oils, vitamin D. Did you hit— did you mention that one?

Dr. Justin Marchegiani: We did not. But vitamin D is definitely important. We have to have to look at potentially even give my baby a little bit extra. I was speaking to one of the in the neonatal uhm— docs there and he was telling me you know, you may want to give your child an additional above and beyond what’s in the breast milk 400IU sublingually uhm— for the baby. So we’re looking at getting some extra bit of that, but, you know, we’re gonna weigh it out. If we can get the kid out there at 8 AM in the morning 15 minutes out in the sun at 8 AM that may be enough, right?  We don’t even need the drops.

Evan Brand: Yeah. What the—lady we spoke with said. She said as long as my wife was getting 6 to 8000 units that which I think this is just probably her making up numbers on the spot but she said that if my wife were supplementing with 68,000 units daily that the baby would probably end up getting at least 500 to 1000 units from that that would pass through.

Dr. Justin Marchegiani: I think that, too. I asked that and they were like, well you should still give it. But it’s probably like a CYA comment.

Evan Brand: Exactly.

Dr. Justin Marchegiani: You don’t know exactly, but I think if she’s getting 6 to 10,000 the day, I think you’re gonna get 5% transfer to the—the baby in the breast milk.

Evan Brand: I guarantee it.

Dr. Justin Marchegiani: I think it’s probably good. So we’re probably gonna make sure she just getting 10,000 a day with the K2 and just get the kid out in the sun a couple times a week in those early morning hours and you know, just enough to give him a little sun kiss. Nothing else.

Evan Brand: Yup. Do you wanna talk about lab test for a couple minutes and just talk about what we would recommend someone get if before they even think about conceiving. You know, we kinda talk about pregnancy and birth and delivery and all that, but really, it begins far before that. So you and I kind of talk a bit like a five or six trimester is really what pregnancy is coz you gotta do the preparation then the postnatal care is important, too. So vitamin D—we hit on that. As a blood panel, insulin or blood sugar if you knew you, had a history, you could get the stuff done. Uh—fasting insulin.

Dr. Justin Marchegiani: The fasting insulin’s great. We want less than seven, ideally, less than five. We may even want to just do some functional glucose tolerance testing, i.e. just testing your blood sugar with a blood sugar meter. Fasting one hour, two hour, three hours after a meal. Choose a couple of different meals a couple times a week, breakfast, lunch and dinner. Some people we hire in the morning coz of the somogyi effect which is totally cortisol driven. So you’ve gotta keep that in mind.

Evan Brand: Yup.

Dr. Justin Marchegiani: And uhm–  I would say, we’re gonna do an adrenal test, for sure. And we may just do a female hormone test around day 20. We’re looking at estrogens and progesterones and such and testosterone, but if there’s a more of a fertility history there, we may run was called the “month-long test” or on the 209 panel from Bio health which is a month-long panel. Will look at progesterone level starting at day 2 every other day in the cycle.

Evan Brand: Thyroid markers. I’m gonna look for antibodies, your TPO, your TG antibodies..

Dr. Justin Marchegiani: Yeah.

Evan Brand: To see if there’s autoimmune going on.

Dr. Justin Marchegiani: Yeah. If there’s some history going on, or symptoms, will definitely do it, but you know, TSH, T4,T3 antibodies, reverse T3’s is great. And you know, one of the things that I give my wife during pregnancy is a couple hundred extra micrograms of iodine a day. There’s some good research about helping the babies IQ. So we did a little bit of that.

Evan Brand: You can have a genius baby now.

Dr. Justin Marchegiani:  Now the goal is to give the kid all of the all the resources it possibly can, right? That’s the goal of you know, being a great mom and great dad is giving your kid as much potential as possible. And a lot of that’s gonna be uhm— healthy pregnancy, right? Healthy nutrition, healthy prenatal nutrition.

So healthy fats, healthy protein, healthy carbs, nutrient density has to be high, inflammation has to be low and uhm— making sure there’s enough calories and good macros. And we’re going a little bit higher on the carbs right now. But this is true when you eat for two.

Evan Brand: A 100% man. Tell me, my wife, she— she ate way more than me and she still—she actually weighs now than she did before she got pregnant which is interesting. I mean—

Dr. Justin Marchegiani: It’s a great benefit in breast feeding.

Evan Brand: It’s definitely depleting, though. It can be depleting, so we’re doing our best to keep her— to keep her full and—and satiated.

Dr. Justin Marchegiani: Yeah. We also did placenta encapsulation as well.

Evan Brand: Oh, sweet man. Yup. Cool.

Dr. Justin Marchegiani: I actually have pictures of a placenta. It’s pretty cool.

Evan Brand: I planted my wife’s with a tree.

Dr. Justin Marchegiani: Really? Wow!

Evan Brand: A little tree sprout, a little maple tree sprout at our old house. I had the placenta coz we’re going to do encapsulation. We had a doula that’s gonna do it for us, so we decided—she felt so good postnatally that she didn’t need it. And—and so I had the placenta in the freezer, took it out so I could actually mold at first, you know, mold it a little bit and dug uh— dug a giant hole, buried it couple feet under with the— with the little maple sapling right there. So there should be a tree there one day.

Dr. Justin Marchegiani: Wow! That’s amazing. So we had it encapsulated, so she’s doing three capsules 3 to 4 times a day. And then we have uhm—we actually had a  tincture made, too, which is pretty cool.

Evan Brand: A placenta tincture?

Dr. Justin Marchegiani:  Yeah. And we’re gonna save that for menopause for her.

Evan Brand: Really?

Dr. Justin Marchegiani: When she transition to menopause, we’ll use that tincture.

Evan Brand: That’s a thrift.

Dr. Justin Marchegiani: Yeah. Isn’t that cool?

Evan Brand: I did not know that. So what’s—what’s the idea there? There’s gonna some naturally occurring hormones in the placenta that will help to ease menopausal symptoms?

Dr. Justin Marchegiani:  Exactly.

Evan Brand: Ahh—Okay. We’ve got uhm—we’ve got a couple questions. I think they may not be related to our topic because our topic’s pretty niche today. But do you want to look at these questions here?

Dr. Justin Marchegiani: Yeah. We try to grab the ones that are most relevant for sure.

Evan Brand: Okay. There was a person named, Chris here, that said he was diagnosed with Hashimoto’s and is displaying signs of hypoglycemia with perfect blood sugar, what could it be? That’s gonna be a good question. Do you get that question?

Dr. Justin Marchegiani: Yeah. So his blood sugar may look good but why does it look good, right? The question is— are the adrenals coming to the rescue to make that

Evan Brand: Uh-hmm.

Dr. Justin Marchegiani: Coz if the adrenals are coming to the rescue and lifting that blood sugar up, there’s gonna be a lot of cortisol and adrenaline in the background which are gonna create a lot of anxiety, and mood issues, and irritability, and a lot of things where your blood sugar may look good, but the question is, what’s lifting that blood sugar up? Ideally, we want healthy blood sugar by diet, meal timing, nutritional density so the blood sugar is lifted up naturally not relying on the adrenals to keep it lifted.

Evan Brand: Yeah. With the adrenals are kind of the backup generators of the adrenals are getting involved with your blood sugar regulation, that’s not good. That means something else is off elsewhere, but if the diagnosis of Hashimoto’s is there, too, could we say that if—if there signs of hypoglycemia maybe it’s not hypoglycemia, maybe it’s thyroid as well because I mean the thyroid can make you feel like your fatigued and lethargy and then all of a sudden, you’re over stimulated.

Dr. Justin Marchegiani: Totally. If you have hyp—If you have Hashimoto’s there’s probably potentially some T4 to T3 conversion issues.

Evan Brand: Yeah.

Dr. Justin Marchegiani: And there’s probably some adrenal issues so all that stuff needs to be looked at and then again, we don’t even know where that— this person is in the hierarchy of diet and lifestyle.

Evan Brand: Right.

Dr. Justin Marchegiani: So we’re assuming that diet and lifestyles are already even adjusted. 30 g of protein in the first waking, eating— eating healthy proteins, fats and the right amount occurs every 4-5 hours or assuming that that’s already dialed in.

Evan Brand: In preferably on an AIP approach and until the antibodies are very, very minimal in the single digits or less.

Dr. Justin Marchegiani: Yeah. If possible, I typically wait till there’s a there’s plateauing of uh symptoms. Some people may not be able to get them all the way low but you know, we at least want to get them under 500 or so. It depends. If we could get  someone under 500, that’s a pretty good reduction.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Again—

Evan Brand: What’s the highest you’ve seen with TPO? I think the highest I’ve seen was like 1600 on a TPO.

Dr. Justin Marchegiani: I’ve seen over 2000. I mean I have patients literally go from over 2000 to under hundred.

Evan Brand: Yup. What’s the timeline? A year?

Dr. Justin Marchegiani:  I’ve seen it happen in six months to a year.

Evan Brand: Yup.

Dr. Justin Marchegiani: Yup. The average person that I work with, we have at least a 50% reduction in antibodies.

Evan Brand: Right. That’s awesome. I love seen that on a piece of paper. When you actually get to validate it, but then their symptoms are better, too. It’s such a double win.

Dr. Justin Marchegiani: Oh and I had so many patients say their endocrinologist just says, “there’s nothing you can do about that”

Evan Brand: No.

Dr. Justin Marchegiani: And it’s like over and over again, and we just continue to prove them wrong and it’s just like, “man!”

Evan Brand: It’s a great feeling.

Dr. Justin Marchegiani: I feel so bad. It’s just like, you know, imagine having someone like, you know, hiring someone to fix your house and all they have is just a hammer. It’s like, “dude, you’re missing the saw and the screwdriver, this and everything” It’s like functional medicine is that we get so many tools at our disposal. We’re not limited to just like that one pharmaceutical tool that’s supposed to be in our toolbox, right?

Evan Brand: Yup. Well the same thing with fertility question. I mean, you and I have  talked to dozens and dozens of men and women who’ve been told that they will never be able to have children, yet we’ve aided, and many, many babies, you know, just being made by helping women get their hormones back on line and fixing the underlying issues, so—

Dr. Justin Marchegiani: That’s it, man. I 100% agree. So, I hope that helps there. Anything else we can grab before__

Evan Brand: Yeah. Let’s see what we have here. That was unrelated questions—

Dr. Justin Marchegiani: Someone was asking about Probio Flora and Sacro Flora. And again, those are some of my probiotic products. Sacro Flora is a high-dose saccharomycin, Probio Flora is a high-dose bifido-lactobacillus uhm—probiotic. We typically do that for at least 60 days after a parasite killing protocol.

Evan Brand: Here’s a good— here’s a good question here from Naomi. She said she’s been diagnosed with blastocystis hominis, which for those listening, that’s a common parasite infection we see. She’s exclusively breast-feeding a six-month-old and the antibiotic metronidazole did not seem to work. “Is it possible to treat while still feeding baby?

Dr. Justin Marchegiani: The only way I would treat it is with probiotics right now. I would not do any herbs. I would choose two probiotics. I would do Saccharomyces and high-dose probiotics that’s the only thing I would do right now to treat it.

Evan Brand: Yup. So, Naomi, when the time comes for you to wean off the baby which if it six months this may be another year or so, we don’t know how long you intend to breast-feed, at that time, reach back out to us. Justin and myself we can help you get rid of the blasto using herbs but, yeah, with these anti-parasitic herbs, we—we just— it’s just not—not a safe. Well it might be safe, but we just don’t know. We don’t know if that’s—

Dr. Justin Marchegiani:  It probably would be safe, but we don’t want a chance and we rather be just conservative, right? Always do no harm. So I feel very comfortable recommending probiotics. There’s been studies done on kiddos, actually, looking at Saccharomyces polarity uh—compared to Flagyl Metronidazole Tri and Blasto, and it’s just as good, if not better.

Evan Brand: Yup. So look it up, Saccharomyces polarity. Check out Justin’s, we both got Saccharomyces polarity products. There’s a lot of good ones out there. Just make sure you get professional grade, so that actually works.

Dr. Justin Marchegiani: Exactly.

Evan Brand: Cool. Yeah, I think that’s it, man. We can wrap it up. Will send people back to your site if you wanna learn more about you or work wit you. justinhealth.com  myself, evanbrand.com  Check us out. We’ve got hundreds and hundreds of episodes. So if we just hit the surface of one piece of the conversation you like today, then I’m sure we dove deep somewhere else and give us a review. I know you may be watching elsewhere, YouTube, Facebook etc. but iTunes is where it counts. So we need to continue to beat out people like Jillian Michaels who promotes just not sound advice and so we wanna really bring functional medicine to the forefront of humanity and help to save some of the crises that are going on in terms of depression, anxiety, infertility, obesity diabetes, cancer. We want to put a dent in the universe. So give us a review so that we can do that and stay in the top of the charts.

Dr. Justin Marchegiani:  Awesome! And you guys, subscribe right now, my YouTube, justinhealth.com; Evan’s YouTube. Uh— click on our YouTube link. We appreciate the subscriptions, care—you know, sharing is caring. We love it. And again, give us feedback. We want feedback about what you guys want to hear because this is all about how we can serve you guys better. So let us know so we can provide more awesome information. And again, what makes us different Evan I different is, we keep it real. You’re gonna walk away from our show and our podcast with actionable item not esoteric BS that’d gonna make sense you up in the ether, right? But what can you actually do. So that’s how we’re different. We’re trying to keep it real and make it actionable for you guys. So we appreciate you listening. And everyone have a great day.

Evan Brand: Take care.

 


 REFERENCES:

https://justinhealth.com/products/sacro-flora/

https://justinhealth.com/products/probio-flora/

https://justinhealth.com/products/trucollagen/

justinhealth.com

evanbrand.com

Analyzing Your Blood Test Part 2 – Comprehensive Metabolic Profile – Live Podcast #151

Dr. Justin Marchegiani and Evan Brand dive into the topic of blood test analysis—specifically the Complete Metabolic Profile (CMP). Learn about the different markers that they look into like the glucose, calcium, BUN, creatinine, Alanine Aminotransferase (ALT), Aspartame Aminotransferase (AST), potassium and sodium. Know about the different symptoms and health conditions associated with the different blood markers.

Gain some valuable information about functional ranges in blood work and understand how it can provide more information regarding health issues and nutritional deficiencies compared to the general reference range. And lastly, discover some healthy recommendations to address nutritional deficiencies.

In this episode, we cover:Analyzing blood cell

2:56   Glucose Marker

6:10   Calcium Marker

8:20   Protein Marker

10:30   BUN:Creatinine

14:12   Liver Markers

 iTunes

YouTube

 


 

 

Dr. Justin Marchegiani: Hey there! It’s Dr. Justin Marchegiani.  I’m with Evan. We’re live on Facebook and YouTube. We’re ready for an awesome podcast. My baby’s doing one week exactly from now we’re really, really stoked. Uh—maybe do a live podcast uh— from the operating room, probably not but maybe something that week, give people some live updates. Evan, how we doin’, brother?

Evan Brand: Life is good. It’s back to school season, so all the school buses are around the city and when people go back to school all of our female clients especially the teachers they start having flare ups of their symptoms. So we got to keep you under control ladies and teachers and men teachers as well. Make sure you’re taking your adaptogens, if you’re going back to school and you’re starting up your teaching again. This is a good time to whip out your—your adaptogen formulas and double the dose of those.

Dr. Justin Marchegiani: Love it. Totally makes sense. Also, congratulations on the new car. You got a great deal on a— on a pre-owned Tesla which is really exciting.

Evan Brand: Yeah. It’s like dropping a spaceship. I’m gonna be putting up a YouTube video. Jack Cruise, who is a mutual friend of ours, he said, “Oh my God Teslas are the worst cars for EMF but that’s actually not true. I’ve actually measured using several devices the EMF from a Tesla. It’s actually not bad. It’s actually less, believe it or not, than Honda Accord that I was driving beforehand. I didn’t take a video so people just have to take my word for it, but the Honda Accord in the backseat where the baby was, I was actually measuring 4 mill gauss, which is a pretty high magnetic field. The Tesla’s actually less than that. So videos and content to come.

Dr. Justin Marchegiani: Unreal. Very cool, man. Well, everything is going here in this front. I’m excited chat with you about today’s topic. Uh—let’s dive in. So, we talked about blood tests in the past.

Evan Brand: Yeah.

Dr. Justin Marchegiani: We talked about the comprehensive—I’m sorry, the uh— complete blood count, the CBC, alright, which is some really cool marker. We chatted about some of the anemia and the B vitamin markers and such. Really cool stuff. Today we want to chat about the comprehensive metabolic profile, the CMP, for short. So really excited to chat about that. Now, let’s go over what the CMP is. So, off the bat, I’ll just kinda give you the list here and we’ll hit the most important ones. Number one: glucose, calcium, we have protein markers, albumin, and total protein. We have electrolytes, including sodium, potassium CO2, and chloride. We have some kidney markers/protein markers including BUN and creatinine. And we have some liver markers including a ALP or alkaline phosphatase, ALT which is alanine aminotransferase or SG PTZ 01. And we have AST or aspartame aminotransferase AST or SGOT, for short. We have bilirubin as well. So let’s start off first with some of the simple ones. So, we have glucose. That’s a really good set kinda general marker. That marker’s gonna be used to look at diabetes, right? 126 or higher is gonna be your diabetes marker. And again, 110 or higher for pre-diabetes and typically, our functional range is gonna be greater than the hundred in the morning is gonna be uh— good a general indicator. Again, glucose fasting is kind of a late stage indicator. It’s not something we want to use as our way to pick up blood sugar abnormalities, in general. I like looking at a functional glucose tolerance. Kind of you can look at fasting in the morning sometimes that can be higher from a cortisol or stress response, otherwise known as the Dawn phenomenon or the somogyi effect. Typically, I like to look at fasting glucose during the day from a functional perspective. So we do a functional glucose tolerance. We tested fasting, let’s say, breakfast, lunch, or dinner and then we look at a 1, 2, 3 hour post meal and just see how that blood sugar is responding. We like below 140 within an hour. Below 120 in two hours and below a hundred in 3. That’s a good general rule of thumb. Ideally, below 120 in one hour and then back around 110 to 100 within two hours and definitely, below 103. That’s—that’s kinda my range. The goal is less blood sugar means less insulin spiking, which is a good thing.

Evan Brand: Yeah, which means less fat storage, too. So when we’re talking about people with uh— a fat loss goal. You’ve gotta have relatively low insulin to be able to do that. If you’ve got high insulin all the time coz you’re eating refined carbs and sugars, blood sugar goes up, insulin goes up, you can’t burn fat. So that’s a really good foundational mark to hit on.

Dr. Justin Marchegiani: Absolutely. I think we need to get a Topo Chico as a—as a sponsor for the show. I love the Topo Chico. It’s like uh—kinda like the sparkling Pellegrino we use here in Texas kinda like a Mexican sparkling water. Uh— absolutely love it.

Evan Brand: Why don’t you email them?

Dr. Justin Marchegiani:  I will. I’ll email them. I’ll make them our show sponsor. I mean, this stuff is awesome, man. It’s like, you know, I used to be a soda addict when I was younger. And I kinda have those, you know, nostalgic memories of drinking out of the glass coke bottle, so it kinda brings it back here.

Evan Brand: [laughs] We need to email them. Just tell them. I mean it doesn’t hurt to ask. So put that on your to do list for today.

Dr. Justin Marchegiani: We’ll get Lululemon as a show sponsor and then we’ll get Topo Chico as the show sponsor.

Evan Brand: That sounds great.

Dr. Justin Marchegiani: Hey, you know, while you’re at it, we might as well reach out to Elon Musk and see if we can get Tesla on board, man. That’d be nice for some complimentary free cars.

Evan Brand: That would be great. I don’t know if that will happen with the—the demand right now.

Dr. Justin Marchegiani: I know. I don’t think that will happen. We’re not the Joe Rogan podcast yet. Alright, so any comments on the blood sugar piece we just uh— brought up?

Evan Brand: Yeah. The blood sugar—you’re always gonna get that run. So this podcast people may say why are you doing this on blood? Your— you guys focus on functional medicine. Well because a lot of people anybody— anybody down the street, your neighbor, your friend, or family likely has some of the metabolic panel stuff that we’re outlining today, plus the CBC from our other blood test podcast, and so, this is designed where if you don’t have functional labs, how can we help you to identify these basic labs at everyone under the sun has access to, regardless of what country you’re in. So yeah, glucose, I think you—I think you killed it with that one in terms of the range. Let’s move on what—what else is on your plate here?

Dr. Justin Marchegiani: Well, we can chat about calcium, too. So calcium is a pretty good marker just for overall blood calcium. Again, blood calcium has to drop down pretty low for them to be a nutritional deficiency.

Evan Brand: Yeah.

Dr. Justin Marchegiani:  And calcium, one of the things I look at when I see calcium go too low, is potential hypochlohydria. Well number one, are we consuming enough leafy greens, right? That’s gonna be a major source of calcium, uh— salmon with the bones major source of calcium. Of course, some dairy products are gonna be great but it just depends, right? Well just use grass-fed butter and ghee over any of the milk and cheese stuff. And if you’re gonna do milk and cheese, you want to make sure that we can—we’re not reacting to. We’re not autoimmune and we’re also, you know, trying to choose raw, organic sources to prevent hormones, the antibodies and also have the enzymes intact to be able to process it. But when I see calcium go too high or too low, I think, potentially nutrient deficiency is number one, right? Not getting the right foods. And I also think low stomach acid and enzymes, number two. And if see calcium go high, a lot of times calcium can be utilized as an inflammatory mediator. So I also look at inflammatory markers when I see high calcium on a flipside.

Evan Brand: Yup. Interesting. Yes. So uh—hypochlorydia, these are the people been popping tums because they’ve got heartburn but in reality they could have something like H. pylori infection or they’ve been on prescription acid blockers which are very, very, very, very common. So if you’re looking at your calcium even if it’s out, sometimes it may be out of the general reference range, let alone our functional range then that’s an issue. Do you have a functional range for us since a lot of people are in the US we may be able to give the measure of units for calcium. Do you have that in front of you?

Dr. Justin Marchegiani: Typically, the calcium range, if I remember correctly will be in the mid 9’s. I think it’s like low 8’s to upper 10. Low 8, upper 8 to low 10’s. So I like in the mid 9’s, it’s a pretty good place. Typically, in the middle of the range, tend to be okay.

Evan Brand: Okay.

Dr. Justin Marchegiani: Any comments on the calcium component?

Evan Brand: No. I think you’re doing good. I’m just kinda uh—walk your hand through this. What’s— what’s next on our list?

Dr. Justin Marchegiani: Yes. So again, I like kinda the middle of the reference range. But next would be uh—protein markers, alright. So we have a couple of protein markers. We have albumin and total protein. And then we also have bun and creatinine, alright. Those are some pretty good markers that we utilize off the bat when it comes to proteins. So number one, I like creatinine above .79. It’s a pretty good place to go right above .79. So for below .79 or maybe some low-protein. And creatinine is a breakdown product of protein as well, alright. It’s a breakdown product, so above .79 if creatinine’s too high, it could potentially be some inflammation going on. It’s very possible there could be some inflammation happening. Uhm— there could be a high workout happening where you know we had a lot of exercise the day before and then we’re breaking down a lot of amino acids from the muscle, right? That’s one component. And then next is inflammation, too, right? There could be some breakdown from inflammation like your kinda—your body’s more in a catabolic state and you’re breaking down. But it can be a good window into protein levels uh—high or low. And then if we look at total protein, I like in the 7. 7 or above is a pretty good place for pro— total protein. If I see it lower, of course, I’m gonna make sure are we eating enough protein? Are we getting about, you know, half a gram per pound of bodyweight? That’s a pretty good rule of thumb, right? They say that 1.2 g per kilogram, right? What does that mean? People don’t think in kilograms in the US, so, I think about a half a gram of protein per pound of body weight. So if I weigh 200 pounds that’s 100 pounds approaching. If I weigh a 150 pounds,

Evan Brand: 100 pounds [laughs]

Dr. Justin Marchegiani: I’m sorry—If I weigh uh— 200 pounds, that’s a 100 grams of protein. If I weigh a 150 pounds, that’s 75 g of protein. And then a good rule of thumb—

Evan Brand: I like your diet, man. A 100 pounds—

Dr. Justin Marchegiani: Yeah. I know, man. That’s it. Exactly.

Evan Brand: Let’s do the BUN: creatinine ratio. So this is something that we see often where this is off. So optimal range, I’ve got a couple pieces of literature here optimal range of BUN: creatinine ratio is gonna be 10:16. A lot of times, we’ll see this altered, where the BUN: creatinine ratio is high. Whether above 16, a couple notes could be antibiotics, could be dehydration, and then in bad cases, some type of G.I. bleeding. So that’s not good. And then you’ve got low issues, where your BUN: creatinine ratio is below 10. This would be issues like we see pretty often. So this would be liver dysfunction, once again, antibiotics, also a diet that’s low in protein. So a lot of older people, I mean, you and I work with a lot of people above age 50, so 50, 60,70-year-olds, they eat less and less protein. It seems they just forget that it’s important they start eating snack foods or their appetite just goes down because they’ve got low stomach acid so they do start to get a distaste for meat. So you’ve really got to use enzymes and HCl with them, ox bile, get their gallbladder working better because if they don’t have a taste for protein, it’s gonna be tough for us to say, you know, “Hey Jack, Hey Jill, we’ve got to get you to eat more protein.” So if you are having a BUN level that is low, or the BUN: creatinine ratio, the BUN: creatinine ratio is low, you might have just a simple issue like not enough protein in the diet.

Dr. Justin Marchegiani: Oh, exactly. Yup. A hundred percent. Now, we talked about creatinine. Now, I’m just gonna crystallize BUN a little bit more. So we talked about creatinine going high, right? Uhm—the potential dehydration as well, potential kind of catabolic physiology rights. That can be a big one. It could be a lot of uhm— creatine supplementation, right? That can be one aspect of—of going high. I just gotta keep that in mind. And on the lower side, of course, will be the protein, right? The low-protein not getting enough of that in there, is really, really important. And then on the BUN side. BUN’s a Blood Urea Nitrogen. That’s another breakdown product. On the high side, we look at hypochlorydia, we can also look at adrenal and dysbiosis, right? And then on the low side, it can be malabsorption, low-protein and low enzymes and liver issues. So there’s a handful of different things that can be implicated either way. I love those as a good rule of thumb of what’s happening. And then we could also look at albumin and globulin. And if we see imbalances in the albumin and globulin, that can also mean issues with protein as well. So if we see like albumin to globulin, I think is on the higher side for globulin and the lower side for albumin, we’re also gonna think of potentially more protein issues.

Evan Brand: Yes. So let’s talk about the biomarkers here. You know, Justin and I are talking about functional ranges. You can make it your blood work if you have it in front of you. You may look at that. It may look okay and actually be in range. According to all the sick people that have been in that clinic. So we’re trying functional ranges. So even if something’s not flagged low or high, or using specific markers, Justin and I have taken some extra training in terms of functional blood chemistry analysis. So we’ve got a tighter reference range. So if you don’t see anything out of range on your paper, it might not be, but the functional range is much, much, much tighter and that’s where we find the issues.

Dr. Justin Marchegiani: Exactly. Typically, it’s gonna be the bottom fifth or the bottom and top 15 to 20% we look at more frequently, like with some of the protein things, some of the albumin high or low. If it’s on the high side, we may think dehydration; if it’s on the low side, we may think low stomach acid or enzymes. And some of these markers kinda contradict themselves, so you wanna kinda look at the complete picture so you can get a window of what’s happening. So I mentioned some of the albumin uhm—there. If you wanna comment on that at all, Evan?

Evan Brand: I was gonna move onto the AST. I had AST notes in front of me. Did you want to hit ALT and AST, the liver markers?

Dr. Justin Marchegiani: Uhm—yeah. Let’s hit that next. It’s one of the common— one more thing on the globulin—So globulin is also one of those things for oxidative stress. So we see globulin go on the high side, that can also mean oxidative stress. Oxidative stress are like, you know, free radical things, right? Oxidation is a loss of electrons. The more you’re losing electrons, the more you want extra antioxidants to help support you out, whether it’s antioxidant, herbs like curcumin, or resveratrol, or green tea, or things like vitamin C, vitamin A, vitamin E. Those kind of things are really helpful. So we have albumin and globulin; We have creatinine; We have total protein; We have uh—those are big protein markers there.

Evan Brand: Good.

Dr. Justin Marchegiani: Next, let’s hit the liver enzymes.

Evan Brand: Yeah. The AST to ALT. I wanted to hit on these because, you know, for my— whether it’s my grandparents, or some of the in-laws, always see markers off with AST and ALT even outside of the conventional range these are some of the markers and I’m gonna see off. So let me give people a bit of background on the— what they call the SGOT, also known as the AST. So this is an enzyme that’s very, very, very prevalent in skeletal muscle, liver, heart, kidneys and lungs. The enzyme can be liberated into the bloodstream following cell damage or destruction. So optimal range here is gonna be 10 to 30 units of A— of AST. If you’re out of the rain, so if you’re too high, this could just be liver dysfunction. So some of the reasons Justin and I may look at your AST and its high, it could be anything that’s affecting the liver. So this could be parasites, this could be bacterial overgrowth, this could be yeast, this could be chemical toxins, like glyphosate. If your diet is not very rich in organic foods, this could be gasoline additives, which is why I got rid of a gas-powered car because my gasoline additives were off the charts on my GPL toxic chemical profile test. Uhm— you’ve got a potential for developing congestive heart failure. So if AST is above 30, so AST—if it’s above 30, and then you’ve got these other symptoms like you have a hunger, your yawning frequently, you’ve got some edema, some of that swelling in the ankles at the end of the day, you’ve got a little bit of shortness of breath with moderate exertion, that may point a picture to some congestive heart failure. That’s possible. Now, the good thing is a lot of that stuff is reversible, but these are just signs that things could go bad. Uhm—and then on AST, you’ve got liver cell damage. That’s possible. So alcohol, that’s huge. We see that a lot with previous alcoholics. People who are trying to get off alcoholics. If it’s tied into the liver, you’re thinking, “If my AST’s high, what’s going on with my— with my liver? Is that the problem?” It could be. Symptoms would be pain between shoulder blades, you’ve got a headache sometimes over the eye, you’ve got those phase 2 liver detox problems, like you’re sensitive to perfumes, or you’re sensitive to fragrances, or you’re sensitive to car exhaust fumes, that’s a big one. Hemorrhoids, varicose veins—that’s also tied into the liver, and excessive muscle breakdown. So if you’re doing a bunch of CrossFit exercise and then you got your bloodwork done, it’s possible the AST could show up high there and that’s not a bad thing. Uhm—

Dr. Justin Marchegiani: Absolutely.

Evan Brand: We got the low side of AST which I won’t take too long to go over but B6 deficiencies, alcoholism. So B6 as we know, Justin and I have talked about it a million times, alcohol burns through some of your vitamin and mineral reserves, so B6 is one of them. And then once again, protein deficiency or malabsorption. So AST, either way, if it’s high or low, your out of that 10 to 30 functional range, we can find a lot of good information out about you.

Dr. Justin Marchegiani:  Absolutely. So let’s go see what once—what we have reviewed so far. so we hit the uhm—the liver enzymes. And again, liver ALT, the alanine, the “L”part, that tends to be more liver, where the AS can be—tend to be more in the heart side, tend to be more on the heart and the skeletal muscle side. So kinda keep that in the back of your head there. We’re looking at these things. So a heart attack, we may see more of the AST elevated and uhm— liver stress more of the uh—  more the AST for the heart and skeletal muscle, more liver for the ALT. But again, things like gluten can easily raise ALT. I’ve seen that. Also, just excessive exercise before, within 48 hours of the blood test could easily raise them of some of those enzymes as well. So kinda keep that in the back your mind.

Evan Brand: Okay. Yeah. I mean, same thing, I want—it sounds like I’d be repeating myself before going over ALT, but functional range for ALT, 10 to 30.

Dr. Justin Marchegiani: Yup.

Evan Brand: Once again is the units. And if people had been doing a lot of uhm— aspirin that could also cause the ALT to go up. So if you’re just somebody who popped—uh chronically pops aspirin, your ALT may go up there. Once again,

alcohols gonna throw off your— your ALT. So pretty common sense really.

Dr. Justin Marchegiani: Yeah. Exactly. And we may also see—if we look at bilirubin, which is a breakdown of a lot of the red blood cells, and if we have excessive breakdown, we may look at potential gallbladder issues or liver, gallbladder stuff going on. So we like, you know, typically, you know, below 1.2 or so, is pretty good for the bilirubin in the gallbladder. If not, we may think there’s some kind of gallbladder issue. We may look at food allergen. We mat really up the bile salts and HCl’s and and lipolitic enzymes— enzymes that really help the fat digestion.

Evan Brand: Yep. Yep. We’ve got— we’ve got a little bit of time left. Should we answer some of these questions here?

Dr. Justin Marchegiani: Yeah. I think so. And the only thing would say is uhm—some of the sodium and potassium and chloride, if we see some of the sodium low, we may think adrenal dysfunctions. If we see some of the potassium excessively high, right, we might think that’s an adrenal pattern of low sodium, high potassium. If we see lower potassium in general, we may think you’re not getting enough potassium, right? We need 4700 mg of potassium a day, so we have to make sure that is kinda dialed in. Same thing with the chloride, I mean, the real easy thing is with the minerals, is number one, we’re getting sea salt in our water, right? High-quality sea salt in our water, half a teaspoon twice a day, we’re eating lots of green vegetables, either cooked, or juiced, or made in away so you can process and digest it down. And then fix the adrenals. These are all things that are gonna commonly be thrown off by adrenal and mineral imbalances. And sugar and insulin can also throw that off, too. Well, adrenal dysfunction.

Evan Brand: Well said. Uh—we got question from—I believe it’s Nalema. Do you have to worry about potassium intake if your bloodwork does not show a deficiency? If you’re eating a pretty good paleo template, I mean, for example you and I have chatted about our love for avocados, you’re gonna get much more potassium in avocados and bananas. So I think if you’re eating an avocado a day or every couple of days, potassium is probably not an issue. What’s your take?

Dr. Justin Marchegiani: Yeah. We’re gonna get one avocado, you get about 1 g a day. You need 4700 mg or 4.7 g. So I would say, if you’re doing six servings of green vegetables a day and you’re doing one avocado, you’re probably  gonna be okay. But I will just throw it into chronometer. Put your height and weight and just ensure that you are getting that 4700 mg, which again is really easy to not get. I think that’s the DRI. That’s the Daily Recommended Intake, not the RDA which is the Recommended Daily Allowance. So 4700 mg, probably good with two servings, probably six servings of veggies and an avocado a day, you’ll probably be okay, but just run it through chronometer to double check.

Evan Brand: Okay. Cool Samuel—uhm a bit off topic. We’ll do a whole show on this. “How do you feel about making your home a smart home?” “Does it create negative effects from EMF like adding nest products and Phillips hue lights?” Not a fan of uh— LED lighting. I’ve chatted with Mercola about that on my podcast and yes, the nest and all the wireless technology, I do avoid that. I’m hardwired everything. No Wi-Fi, hardwired Ethernet. And uh—funny enough I’d been wanting to turn off the breaker to our bedroom so we could sleep better. And all the sudden the power to the bedroom has been off, but all the breakers look fine. So I don’t know if someone from the universe magically cut off the power to our bedroom, but even though the breakers look normal, there is no power in the bedroom and I’ve been surprisingly sleeping way deeper. Uhm— but we could do a whole show on that, but ideally you stay away from the wireless stuff or you just turn down the intensity of your— your products if you can.

Dr. Justin Marchegiani:  Yeah. I’m on the opposite side of that. You have the nest. I do have the nest. I do love it. I think it’s absolutely awesome. Uhm— and again, for me, I have my Wi-Fi on a wireless timer so once 11-11:30 hits, all my Wi-Fi goes off for the night. And that includes nest and everything. So I set it up so during those hours of sleeping, they are not on, number one. And number two, I have— I used a very, very high-end EMF meter and I’ve tested the nest and such and really, the EMF comes out in those first 10 feet or so, away from it.

Evan Brand: Yeah.

Dr. Justin Marchegiani: So I’ve been across the room or sitting in my couch and I aim it at that or it get caught and it’s few—and it take—you got to be pretty close to get that EMF out.

Evan Brand: Yeah.

Dr. Justin Marchegiani: You really do.

Evan Brand: Yeah. Distance. I think your distance should probably much safer. I started doing the Wi-Fi on a timer, then I thought, “What the hell, if I’m sleeping better without it, what am I sacrificing during the day being at home with it. So that’s why I’ve just went hardwired. Maybe I’ll go back, but for now, I’m hardwired and I feel pretty good.

Dr. Justin Marchegiani:  Yeah. I mean—its just, like for me, like I’m at the airport, I’m coming in and it’s like my house is like a hundred degrees. I’m like, “Oh, let’s get it cool, or like, you know, we go away and if like uhm—we’re out of the house, right? It’ll take the temperature up a little bit.

Evan Brand: Right.

Dr. Justin Marchegiani:  You save a little bit of money on—on that side of the fence. So there’s pros and cons. I think uhm—if you can like—I’m hardwired right now. But I think if you can put your thing on a Christmas tree timer at night, I think you really, you know, you can at least have it off when you’re sleeping, which I think is really important. I also sleep on a ground and I have EMF blockers in my room as well.

Evan Brand: Yep. For sure. Let’s keep going. Uh—let’s see what else we’ve got here.“What are some blood test markers for thyroid issues?” I believe we did a whole podcast on this.

Dr. Justin Marchegiani:  Yeah. I would see the whole podcast on that. TSH, T4, T3. Real quick, TSH, you know, below 2.5; 1’s ideal; T4 free: 1 to 1.5; T4 total: 6 to 10; T3 total: 100 to like 150-160. Again, go see the podcast on that. We’ve riffed on it for over an hour at a time, so check that out.

Evan Brand: Yeah. Another question is “Redmond’s real salt worth it if you’re having pink Himalayan salt?” I think so. I switch out. I have a lot of salt Celtic sea salt, I’ve got all sorts of different types and flavors and sources. I think they’re all helpful and they’re not gonna hurt you. It’s in that category of my help— not hurt you.

Dr. Justin Marchegiani: Yeah. And I think, Redmond’s in my opinion just taste better. It dissolves really well in the water. So you throw it in there, dissolves really nice. I mean I’ve used Himalayan and Celtic— doesn’t quite dissolve as good. Maybe there’s a more, uhm—you know, a version that’s ground-up better so it absorb as more soluble in water. But I like the Redmond’s. I love the taste. Love it.

Evan Brand: Yeah. It does taste good.

Dr. Justin Marchegiani: Yeah. It’s very good. And it’s lower in —

Evan Brand:—We do the same. Turn off the Wi-Fi after 10 so that’s cool like I said, I used to, but then I’m like, “Yeah, I’m gonna just get rid of Wi Fi completely especially after I was in a Dr. Klinghardt talk about “How you can detox heavy metals if you’re exposed to Wi-Fi” which is pretty interesting on his latest talk. I was like, “Whoa! That’s pretty nuts, so—“

Dr. Justin Marchegiani:  Yeah. I mean, I think what happens is you get some people who are the exception to the rule.

Evan Brand: Yeah.

Dr. Justin Marchegiani:  Regarding their high level of sensitivity and then you get a lot of practitioners that had had success with that one person.

Evan Brand: Right.

Dr. Justin Marchegiani:  And they they start— this is the rule for everyone. I think that’s really excessive, but if you are chronically ill, should you try it? Heck, yeah. You should try it.

Evan Brand: Yeah.

Dr. Justin Marchegiani:  But it may not be the end-all or be-all. I mean, I love the convenience of having Wi-Fi. I don’t know this as much, Evan, but I do know that, you know, I’m sleeping at night. Maybe I’ll get into a little bit deeper REM sleep. So I’m not using it at night. I get no benefit by keeping it on at night. So why not just turn it off, right?

Evan Brand: Right. For sure. Uh—we got a question from Vevec. He said uh—“How to differentiate between type I and type II diabetes? Any diagnostic test?”

Dr. Justin Marchegiani:  Yeah. I mean, type I is gonna be an autoimmune condition. So what’s gonna happen is uhm—typically it’s gonna happen in the first 12 to 13 years of life. That’s when it mostly happens for kiddos. And their reality tend to be behind it, but one of the big things that you’re gonna see, is you’re gonna see just blood sugar just going up super, super high, right? The reason why it’s going up super, super high is because the insulin isn’t there by the beta cell so it cant’ let the—the sugar get into the cell. So you see blood sugar come up super, super high. These people tend not to be big and be more small. You know, more uh—I should say smaller because they don’t have the insulin bringing the sugar into their cell to get the fat up.

Evan Brand: Yup.

Dr. Justin Marchegiani: But you can also run what’s called the C-peptide test, which will look at the uhm— the beta cell function of the pancreas. And if you see C-peptide on the lower side, uhm— then you’ll know. And you can also run uhm—type I diabetes. I think the beta cell antibodies. You can run to also confirm that too, or pancreatic isolate cell antibodies to confirm that. So there are different things you can do to assess. But you’re gonna know because you just— you’re getting emaciated uhm—and your blood sugar’s off the charts high, for sure.

Evan Brand: Yup. Uh—last question we can take care. Shayna, “What is over a 115 vitamin D level? I mean I don’t take a vitamin D supplement.” First, we gotta make sure that’s actually the vitamin D not the 1,25. That’s a kidney marker but the 25OHhydroxy vitamin D marker. You gotta make sure it’s that one. If it’s that one and you don’t supplement, I’m not too sure. I’ll see if I can find something. Justin, what’s your take?

Dr. Justin Marchegiani:  Yes. Same thing. I would just—I would look at what your—what the marker is. And then number two, maybe you’re getting out in the sun a lot or maybe your—one of your supplement has some vitamin D in there, you’re not aware of it coz that’s pretty high to get to naturally. So  maybe you’re sunbathing a lot, maybe that’s totally natural. I would just double check that and make sure that’s the case. But double check if it’s 25 versus the 125. That’s the big thing I’d say.

Evan Brand: Yeah. I mean my wife’s prenatal, for example, there’s a lot of vitamin D in there. Those other formulas that we’ve taken that have vitamin D, so you could really add up to six or eight or 10,000 IU pretty pretty quick. So, yeah, I second that. Look at your protocol. Make sure there’s nothing in there.

Dr. Justin Marchegiani:  Absolutely. Let me just knock up just one more question here. So regarding alkaline phosphatase—Yeah, less than 50 is low zinc. Again alkaline phosphatase is an enzyme that correlates with zinc. So it’s— it’s a metalloenzyme so when the enzyme’s lower, we tend to have lower zinc. You can also test it Zinc Tally test get some zinc—I think it’s zinc chloride or zinc sulfate.

Evan Brand: Yup.

Dr. Justin Marchegiani: It’s the liquid zinc. And then basically the better it tastes, the cleaner and the more like water it tastes, the less you need it. I’m sorry—the more you need it—the more you need it. The more metallically it tastes, and you know, the more metal it tastes, the less you need it. So that’s a good kinda rule over time to kinda look at. And then A1C—again is a marker for blood sugar. If A1Cis really low, right? We want to look at other markers to correlate anemia. So if we see MCV, MCH, MCHC on the higher side, that could be in some kind of B vitamin anemia or if we see RBC hematocrit hemoglobin below, that could be another indicator for an anemia.

Evan Brand: Oh, we got one more question and then we’ll have to wrap it up. It just gets addicting answering questions.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Abner—he has buddies telling him it’s ideal to spike insulin before weight training. Is there any benefits to it? I mean, I’ve always thought the exact opposite that you want to have a little bit of a spike after—

Dr. Justin Marchegiani: Post work out training.

Evan Brand: –weight training.

Dr. Justin Marchegiani:  Post work out. The reason why is people are incredibly anabolic. Most people that have high levels of insulin, it’s anabolic in the terms of uh—generating fat cells, right? Coz anabolic means to grow in fat cells. But if you can use insulin post work out, you can basically have the key to drive protein into the cell. You’re also driving which is gonna help with, you know, protein synthesis, ideally building more muscle. It’s gonna help spike mTOR and then you’re also gonna have effects of driving sugar into the muscle, which it’s just wrung out all that glycogen during the workout. So you’re repleting the glycogen which will have some anabolic effects and it will uhm—it will help lower cortisol, too. It will drive down some of the cortisol because the cortisol has made all the blood sugar so it’s gonna pull all that sugar from the cortisol into the muscle so it can be used to help generate hypertrophy.

Evan Brand: Yup. I just did a little bit of research on vitamin D. If it’s super high, it could be a buildup of calcium in the blood. So other symptoms that could go along with this could be poor appetite, nausea, vomiting, weakness, frequent urination, kidney problem. So maybe look at your other markers on your blood test. See if you got anything off with your calcium, you got anything off with some of the kidney markers and then if you’ve got those other symptoms— frequent urination, things like that, definitely take a look.

Dr. Justin Marchegiani:  Yeah. It’s almost always from a supplement so just stop—stop taking the supplement if __ vitamin your body will eventually clear it out in a few days to a few weeks.

Evan Brand: Yup. It should be pretty quick. Well, cool. Any last things you wanted to say before we wrap it up. I think we did a great job on this one.

Dr. Justin Marchegiani: Yeah. This is probably my first—my last podcast uh— without a kiddo. So I’ll be officially a dad uh— next time that we are on the air. So pretty excited about that.

Evan Brand: Me too. I’m pumped for you.

Dr. Justin Marchegiani: Can you give me like one fatherly tip or advice here before we go.

Evan Brand: My fatherly advice is just you—you take it day by day and when something happens where you could see yourself stressing out, just remember you have the ability to control how you respond to something. So I like— when the baby is super fussy, and you’re trying to figure out is he tired, is he uh— hungry what is it? I just like take an extra second it’s like, “Okay, let’s run through the day. Okay, the last feeding was this. Okay, maybe it’s too warm in here. Maybe a little too cold.” Before I let my sympathetic nervous system kick in to overdrive, I try to walk through the situation step-by-step and then, “okay” and then that way, I don’t make myself sick by the extra stress.

Dr. Justin Marchegiani:  Right. So instead of getting mad at the situation, you kinda like take a step back like kinda problem solve or think what could be the issue before you have an emotional response.

Evan Brand: Exactly, dude. Try—try to not have the emotional response.

Dr. Justin Marchegiani:  Right. Try to be more—more logical than emotional about it.

Evan Brand: Which can be hard when you’re tired, and your sleep is interrupted and stuff like that, but you just get better and better every day at it.

Dr. Justin Marchegiani:  Appreciate it, man. Excellent.

Evan Brand: Yup.

Dr. Justin Marchegiani: Hey, today was a great chat. Let’s do more, probably in the next two weeks here, but maybe I’ll jump on here while my little paternity leave here for the week.

Evan Brand: No rush, man. You deserve it. You earned it. Take that paternity leave. Will be here waiting for you when you get back and uh—if people want to schedule, in the meantime with Justin, may be a little bit till he gets back. Til his back in the trench but uh—justinhealth.com He will be ready and willing and for me, evanbrand.com you can schedule with either of us. In the meantime, make sure you subscribe if you’re watching on YouTube and we’ll chat with you again soon.

Dr. Justin Marchegiani: It will be a lot of sleep in down time so maybe I can sink one up in there, so we can have a chat in between.

Evan Brand: Sounds good.

Dr. Justin Marchegiani:  Alright, Evan. Great chat. You have a great day.

Evan Brand: Take care.

Dr. Justin Marchegiani:  Take care. Bye.


REFERENCES:

justinhealth.com

evanbrand.com

Redmond Real Salt

Lululemon

Topo Chico

https://www.tesla.com/elon-musk

http://podcasts.joerogan.net/

 

Immune System, Tapping Technique and GI infections – Podcast Live with Dr. J and Evan | Podcast #131

Dr. Justin Marchegiani and Evan Brand engage in a lively and informative discussion about their recent clinical successes with their patients using the functional medicine approach. Listen to them as they dig into the root cause of their patients’ issues and turn chronic and seemingly complicated problems into success stories.

Know about the tapping technique which involves turning something negative into a better, positive thought. Learn more about GI infections, the bacteria or parasite that may be involved, as well as the tests and treatment options that are proven successful in the functional medicine world. 

 In this episode, we cover:

 03:50   Immune System, bacteria, and infection relationship

 15:50   Tapping Technique

 19:17   Treating Hypochloridia

 24:10   GI infections

 28:34   Enzyme Tests
 
itune

 

 

youtuve

 

 

Dr. Justin Marchegiani: We are live on YouTube here. Podcast live on demand. Also, live here on Facebook. Evan, how are you doing, man?

And again, Facebook people you gotta click on the link here uhm—I’ll put in the comments to see Evan’s pretty face and go back and forth on this. How we doing, man?

Evan Brand: What’s going on? I’m feeling really good today. We’ve got a blue skies, the trees are blooming which they probably—

Dr. Justin Marchegiani: Awesome.

Evan Brand: a year ago in Austin. So I’m enjoying myself.

Dr. Justin Marchegiani: Very good. So we got podcast on demand. So anyone wants to write in some suggestions as we chit chat here, we’ll figure out what exactly we want to talk about moving forward.

Evan Brand: Yeah. And I might as well post a link over here to my Twitter page and see if uh—people are paying attention over there. That way, if they’ve got questions, they can get them answered here.

Dr. Justin Marchegiani: Love it. Totally makes sense. Same thing, anyone on Facebook, too, every  chimes in first we can get this thing moving. But let’s uh—just talk about some clinical successes in the last week with patients. Any updates from you, man?

Evan Brand: Yes. So interesting update is uh—there’s a female client that comes to mind and she had seven, I believe, I have to go back at here stool test and count. But I believe it was seven infections and this is a combination of two parasites which—let me just pull it up, that way, I’m not just shooting into the dark here, but—Uhm— with these infections, we started a gut protocol and symptom improvement was seen. She was having a lot of irritable bowel symptoms uhm— running to the bathroom. So she showed up with H. pylori, Blastocystis Hominis, Entamoeba and Fragilis and Proteas  and Citrobacter. Somehow, cal protectin level was still low  which is intestinal inflammation where—

Dr. Justin Marchegiani: Yeah.

Evan Brand: –I look at but I was surprised. And so anyhow, we put her on this protocol. And this is like 8 weeks.  And the H. pylori while it’s still positive, instead of two viral factors, now she’s got one viral factor. The level of H.Pylori has dropped. The Citrobacter is completely gone. The Proteus completely gone. The Blasto is completely gone. But we still got Entamoeba. So there’s still the parasite and there is still the H. pylori there. So we’ve got work to do but yet, we’ve seen 3 or 4 things disappearing. So I think what the takeaway message is from me is that the bodies gonna heal in an interesting way. It may not heal everything at the same time. Some things may be easier to kill. Some things may disappear first, but you gotta heal yourself especially your gut, your microbiome. You gotta heal these things in layers. And that’s what we’re seeing here.

Dr. Justin Marchegiani: Yeah. So typically with a lot of patients that have chronic issues is there are some underlying stress, right? Emotional, physical, chemical stress but even deeper above and beyond that, there is some level – there’s some level of  infection that’s deeper that creating inflammation even though it didn’t show via calprotectin or it’s just creating leaky gut. And the whole leaky gut mechanism is getting the immune system fired up. The more the immune system is fired up, it’s just an energy suck for  your body. It’s like uhm—let’s say guests in you guest bathroom that you never go into your house. And they just leave the water on. Just a little bit—little drip, drip, drip. And then you get your water bill at the end of the month, and you’re like, “Where the heck did that bill come from?” And you’re like, “Oh, yeah. The faucet’s on.” But it’s like that with your energy resources. When got these bugs, it really—when the immune system is overactive. And even just a leaky gut, right? The more your immune system is overactive, the more it’s gonna suck your energy dry. That’s why when you get sick, the first symptom you get when you get sick is what? You get a lot of fatigue and malaise coz the immune system is sucking resources. Go ahead—

Evan Brand: I wanna hear uh—a recent case from you, but first I wanna ask you the question that I get asked all the time. And the answer really doesn’t matter because we need to fix the root cause no matter what. But people often ask well– chicken or egg? Was it that ma—my immune system got taxed first? And then I picked up these bacterial pathogens or these parasites? Or did I pick up the parasite and the bacterial pathogens and then that that set my immune system? What’s your take? Can it go either way?

Dr. Justin Marchegiani: Yeah. So typically it’s one of two scenarios, right? Typically someone gets exposed to a very high amount of infectious debris, right? Parasitic—parasites. So you drink some really bad water, you to go Mexico, you have really bad meal or at a foreign country, you get the Bali belly, so to speak. And then you’re overwhelmed with all of that infectious debris and then there’s so much of it that it compromises your immune system, you get diarrhea, you have a lot of gut inflammation that creates malabsorption. That malabsorption puts stress on all of your glandular systems and then you spiral downhill. That’s scenario number one. So just the infectious—the infection was so overwhelming, it just threw everything else downhill. Scenario number two is there some type of immune compromisation  that’s happening. Meaning adrenal stress, poor diet, poor sleep, or poor diet and lifestyle habits, low nutrient density. The immune system’s kinda a little bit weaker underneath the surface then you get exposed to some of these infectious debris at smaller micro levels that are in the food. And eventually makes its way to the system and creates inflammation.

Evan Brand: So yeah—so let me—let me clarify there. If we’ve—If we’ve got diet, lifestyle mostly dialed in, but let’s say people are cheating with gluten, for example. They still got intestinal permeability going on. You can still have good class, good sleep, blah, blah, blah. But if you’ve got just a simple thing like leaky gut, for example, you could potentially be more susceptible to pick up these infections regardless of whatever else is dialed in.

Dr. Justin Marchegiani: Yeah. I mean—here’s the deal with leaky gut, too. If you’re creating leaky gut, and then there’s some research, you know, on the non-celiac, gluten sensitivity side of the fence, that looks at these foods. Even if you’re not like reacting to a it, like symptomatically, and even if you’re not like having like IBS -like symptoms,  bloating, you know, gas constipation, diarrhea, that gluten can still create leaky gut. Where the undigested food particles in the gut can make their way into the bloodstream and create stress. And then the LPS that comes in there along with that, that’s the— the bacterial debris can get into bloodstream and create a lot of mood issues as well. So you can still have leaky gut and not risk from gluten— and still not respond to gluten in general.

Evan Brand: Yup. Yup. I just posted a post on uh—Facebook which I think might be a slightly controversial which was I wrote this little bit of a letter and I put kind of like these five things that have happened over the last year or so where people have said, “Evan, I’ve ditched psychiatrist or I’ve ditched my psychologist or my marriage counselor, or my conventional doctor because of functional medicine.” I kinda wrote the reasons why of how if you lower inflammation, you may need less adjustments at the chiropractor, for example. If you heal the gut, you start producing your neurotransmitters optimally, you might not you’re your antidepressants anymore, so you might not need your psychiatrist. Or if you heal your adrenals, you’re not gonna snap at your children anymore, so therefore you’re not gonna need the marriage counselor that is telling you need to stop yelling at your kids. And how basically how functional medicine can literally, not intentionally, but it’s just a side effect is that we can replace these other industries. I’m not saying these other industries are bad for mental health care or anything like that. But a lot of times, this is not root cause medicine. And my wife and I went out you with a friend of ours yesterday and she said she had a lot of stress, she had to put her dog down and she called up her psychiatrist and said, “Hey I need help, I’m freaking out.” What does he do? He prescribed her 60 Xanax and says, “Here’s your Xanax bars and take these.” And I told her, I said, “Listen, your anxiety and your stress from this issue is not a Xanax deficiency.

Dr. Justin Marchegiani: Totally.

Evan Brand: How about we do some emotional freedom technique. We start tapping. How about we cleanup the diet? And then before we left, out the parking lot, I had her do the quick coherence technique, the Heartmath, like the heart focus breathing.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And focusing on someone that she loved and we got done with it, and she said, “That was weird.”  I said, “What happened?” And she said, “I got tingly and warm.” I said, “Oh, it worked.” And she said, “What happened?” I said, “Well, you just took yourself out of fight or flight that you’re probably stocked in which is causing you to be dependent on Xanax and now we’ve pushed you into that parasympathetic rest and digest mode.” And she feels better. And this is what this is all about. Uh—a little bit of uh—off-subject uh—, but I just wanted to mention to people, check on my Facebook post and you’ll read about what I’m saying. I’m not saying these other uh— practitioners out there are garbage. What I am saying is that if you’re not getting a practitioner to focus on root cause, even if they are psychiatrist, if they’re not a root cause psychiatrist, then what the hell are they doing?

Dr. Justin Marchegiani: It’s all about resources, right? And in functional medicine world, we’re trying to help enhance your resources. So just like someone with more money in their bank account can buy more things, well if we enhance our mental, emotional bank account via healthy and diet and lifestyle functional medicine principles, we have more resources to deal with stress in our life. Whether it’s family, friends, being a parent, being present for our partner, just being able to do the hobbies of a hobbit—hobbits—uh—

Evan Brand: Haha

Dr. Justin Marchegiani: The hobbies and the habits that we have going on in our life.  I got uh—I guess I’m missing my uh – Lord of the Rings movies there. Yeah. So—It ‘s all about resources, right? So we have to make sure that we have enough resources in our system so we can allocate them toward these stressors. And I always tell my patients, “Have you ever tried dealing with stress on 0 night sleep? or “Try doing your taxes the next day when you’re getting like three hours of sleep?”  You’re just  not gonna be able to handle it. You don’t have the resources. So everything we’re trying to do is let’s test the resources of our body systems, let’s look where the hormone’s at, let’s look at where the gut resources are at, let’s look at detox and nutrient resources are at, let’s support them and let’s work on fixing them.

Evan Brand: Well, the analogy I like to use is we’re just using a big spotlight. Because a lot of different industries and health care, what they do is they use like a little laser pointer or like one of those tiny little keychain flashlight. And they shine something real dimly into one corner. And you’re like, “Oh, Justin looks like we found something. We found some anxiety issues, here’s the Xanax.” But instead, we come in with a giant spotlight and we’re like, “Whoa, look at the left corner of this microbiome. We got parasitic and bacterial infections, which can steal your nutrients, can mess up your blood sugar and cause anxiety. Look over here,  we’ve got some adrenal issues. You got spiking of cortisol that’s gonna need to be addressed.” And then we shine the spotlight over here, “Oh, take a look at our detox pathways on the organic acids, you’ve got trouble over here.” And “Oopp, we shine the spotlight behind us, here’s mitochondrial issues. This is why you’re so fatigued.” And that’s the—I think that’s the greatest analogy. It’s a little laser pointer or a little small keychain flashlight, which is just pinpointing one industry of psychiatry or psychology or whatever versus exploring everything. Which is why for you and I, it’s tough for us to become the blank guy. You know people out there, “the thyroid guy” “ the detox chick” “ the bone broth chick” You know what I mean? It’s really gonna be tough for you and I to just say we’re the blank person because I don’t want to limit myself. I wanna let everyone know it is all encompassing.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And if rest and niche yourself down, I think it’s a bad thing.

Dr. Justin Marchegiani: Yeah. Like from a marketing standpoint, right? Marketing is just telling the truth attractively. You know it’s good to have the niche because you wanna reach the people that have special conditions. Because if like, my specialty is thyroid. Number one, I have—I have or had a thyroid issue. It’s under control. Autoimmune thyroid issue. So I’m more passionate about that issue. But again, to treat  a thyroid issue, you have to be able to treat all of the systems. So it’s kind of a mythology, like you don’t just ever treat thyroid, you treat the whole thing. But you may mark and put information out there that’s gonna resonate and speak to someone with a thyroid issue more. But again, the underlying issue is from education and clinical standpoint. We’re addressing the key underlying surface issues and the deep root issues as well. So we’re never ignoring it. We may speak to someone uhm—more specifically and get into the more nuances of that condition, but it all comes back down to the foundational stuff that we always talk about.

Evan Brand: Right. I would say my specialties would be— it’s become parasites really. I mean, I’m seeing so many each week and it’s just so fun. I guess because I had parasites.

Dr. Justin Marchegiani: You had a parasite, you.

Evan Brand: Uh—Yeah. And also depression, I mean because depression is what got me into this whole thing. IBS and depression in college, I mean, like I told you before, I had to figure out when I went  into a college class, where’s the bathroom. Coz I have to get out in the middle of the class to run to the bathroom.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And so for me, depression, IBS, parasites, you know, those are all linked together—the whole gut-brain connection. And I really am empathetic for people that have struggled with that because it’s so common and if you diagnosed with IBS, that’s a pretty generic diagnosis. And unless you’re with functional medicine practitioners, you’re gonna get an acid blocker, an antispasmodic—

 Dr. Justin Marchegiani: Yeah. Absolutely.  

Evan Brand: — or some other drug and—

Dr. Justin Marchegiani: Well actually, you were diagnosed with IBS, right?

Evan Brand: I was.

Dr. Justin Marchegiani: And you use the antispasmodic, you used the medications that helps with the gastroparesis. You know—

Evan Brand: Well, they never –

Dr. Justin Marchegiani: They even do that—

Evan Brand: Well they never got to use it. They try. They wrote me the prescription pad but I denied all three of the drugs.

Dr. Justin Marchegiani: And the thing is, too, we can also use natural medicines for a lot of those things. That may not fix the root cause, right? There’s root cause medicine and there is using natural medicine in a way that’s gonna help alleviate the symptoms that’s gonna up regulate physiology so things work better. But we have to still be investigating and digging to the root cause, right? So we’re dealing with someone with gastroparesis or low motility, we may add in things like ginger. We may add in things like carnitine. We may add, you know, higher amounts of mag citrate to keep that uhm—migrating motor complex moving. But we are still digging in deep. We’re still making the diet, the lifestyle. We’re still enhancing digestive nutrients, uh—hydrochloric acid enzymes. And then we’re digging deep for the infections. And we’re trying to lock in those diet and lifestyle habits, right? The supplements are great because they can give us that symptomatic relief while we continue to dig over here to the root cause. So as long as you have, you know, that  four pace envision that addresses some of the symptoms without the side effects, you know of some of the drugs, which may have more side effects than what you’re treating, and then working on the functional medicine plan, I think we’re in a really good place. 

Evan Brand: I agree. Yeah. I actually got a good—good success with that IB Synergy product from designs which get Bonigut in there. It’s got the 5-HTP. I had a guy with just super bad IBS and I said, “Man” I mean he was critically, critically stricken with both diarrhea and constipation just alternating every other day.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So I have him going with that 5-HTP Bonigut blend. And he got better. Now we start to wait for lab results but yeah—I mean  sometimes we will do some of the quick fix of band-aid situations to fix things, but we still got to work backwards. I guess to answer these questions uh—should we answer the question about the cancer question here or shall we just make a whole show on the future?

Dr. Justin Marchegiani: Yeah. We’ll do a whole show on that. I’ll get some experts on. I got Dr. David Jocker is coming next month as well. He was in the truth about cancer series. And we’ll go on ketogenic diets and we’ll talk more about therapeutic ways to address cancer outside of just the natural chemotherapy. So we’ll hold that one that—we need more time for that.

Evan Brand: Yeah. Agreed. Uh—Samuel asked, “What is the tapping technique? Can you show us? Well since most of our audiences are gonna be audio listeners we’re not gonna take up the air time to show you the technique, but the best resources—EFT (Evan-Frank-Tom) EFT.mercola.com and you can just view the different acupressure meridians that you’re gonna tap. But then also, you’re gonna learn about the affirmations that you can use for emotional freedom technique and that’s something Justin and I use all the time.

Dr. Justin Marchegiani: I think it’s helpful. I’m—I’m gonna just give it 15 seconds of airtime here, so—just—I do two hands coz it’s adding it’s more efficient. But you just tap the  inners part of the eyebrow, the outer parts of the eyebrow, under the eyes, I do under the nose, and the bottom part of the chin the same time. And then I do both collarbones. So I do this, and you can go top of the head and tap midline. So I do two hands coz I just feel like you get more stimulation. So I go here, and I’m just thinking about whatever is pissing me off, my wife, I just think about it.

Evan Brand: Haha

Dr. Justin Marchegiani: I kinda give it a number. So if I’m a t like 6/10 regarding irritation, I just think about it. Whatever that issue is, whether it’s like, you know, the person driving  in front of me is so slow  or whatever. And I try to knock that 6 out of 10 so that 10 is the worst.  6 is like 60% to being at the worst. I try to knock it down to a4 to a 3. And so every round—every 2 rounds or so, you kinda just check back in and see if you knock it down. And you go as you kinda knock everything down to a 3.

Evan Brand: Yeah. And we have—I—I start at the top of the crown which I usually like—many ways—

Dr. Justin Marchegiani: You can do that. You can start there, you can end there.

Evan Brand: Now do you do the sides? I know Mercola, he’s big on the side of rib cage under the armpit.

Dr. Justin Marchegiani: Yeah. I do that, too, sometimes. It’s just wasn’t good for a video.

Evan Brand: Yeah. So you criss cross?

Dr. Justin Marchegiani: Yeah. I do two at the same time just coz it’s stimulation.

Evan Brand: No. I mean you criss cross your arms so the underarm’s like this. I do like a monkey.

Dr. Justin Marchegiani: Haha

Evan Brand: And then—and then finish with the wrist. I typically finished by tapping the insides of the wrist together then doing the affirmations. So even though I’m angry, or even though I’m anxious, I deeply love and accept myself. But you gotta say the affirmation verbally. I tell people if you can, if you’re just embarrassed, then don’t do it. But why be embarrassed? Nobody—nobody is paying that much attention to you.

Dr. Justin Marchegiani: Yeah. That depends, too. Like you can do this stuff, and you can kinda say like if you’re at—let’s say, if you’re lying in bed and you’re just really stewing on something and your wife’s next to you and you don’t wanna wake her up, then you can just kinda think it in your head. And then you can just, you know, do the affirmations, tap like this.  And then you can tap here, and think about the issues.

I like them to end, though, with a positive thing. So you can end with something positive. So then I just go into like, “What is it that I want to manifest?” So I’m going into right there. I’m thinking about whatever I’m gonna try to create or produce in my life, I just tap it while I’m thinking about it. And the whole idea of tapping is you’re just stimulating various meridian systems that have been mapped out via acupuncture system for thousands of years. And really what it’s doing is it’s neutralizing the negative response that’s stored in the limbic system or in that subconscious of your—more in the psychological side of it. And you’re trying to kinda rewire it so you can get a good pattern there instead. So then, naturally that reflux is to go back to the better thing and not to the negative thing.

Evan Brand: So if you do affirmation about the bad part, would you do like an affirmation about the bad part and an affirmation for a positive?

Dr. Justin Marchegiani: Yes. So I start off with the negative and just try to lessen—lessen it first.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Coz if you’re—feeling negative, it’s really hard to be positive when you’re negative so I try to decrease the negative to about a three. And then I go into the positive because then, you are in a better place to deal with the positive, right? It’s kinda like when someone tells you to relax and you’re pissed off, like relax, calm down. You just wanna punch him, right? Like, “No, I’m too wound up, come on.”

So I wanna get that dialed in and then now I’m relaxed, now I can rewire it and create some positive things.

Evan Brand: I like it. I like it.

Dr. Justin Marchegiani: So calm down first, and then work on manifestation.

Evan Brand: Should we answer a couple of more questions here?

Dr. Justin Marchegiani: Yeah. Let’s hit it, man. Let’s hit it.

Evan Brand: Solam asked, “How long does it take to heal hypochloridia?”

Dr. Justin Marchegiani: It totally depends, right? If you have emotional stressors that are unresolved ore you’re eating foods that are incredibly inflammatory, maybe never. But if you’re making the root causal changes and your managing your stress, and you’re fixing the underlying gut stuff, I would say within 3 to 6 months, you have a really good chance of not needing hydrochloric acid to digest your food. But again, everyone is different. A longer—the longer the issues been going on, the more severe the infections, and the more infections that are layered in there, I’d say longer, up to a year, at least.

Evan Brand: Yeah. I’ll just have my two cents to that, too. If you had a previous history of a prescription, as a blocker’s proton pump inher—inhibitors are now it’s open to counter like the Xanax or the Toms, or anything like that, or—

Dr. Justin Marchegiani: Yup.

Evan Brand: Or if you’ve had H. pylori which we’ve chatted about many times, then I would say it may lengthen that time, too, to fix that stomach acid issue.

Dr. Justin Marchegiani: The longer that gut’s has been worn down, the more the immune system is revved up like you get patients are just supersensitive to every little thing. Like I can’t even put in an enzyme, I can’t even put in our apple cider vinegar or lemon juice or the smallest fermented food sets them off. It’s really hard and you’re looking at a couple of years to really dive into it because the immune system is so revved up and it’s so ready to attack the smallest invader that it’s so hard to put things into help and heal it because it’s looking at everything as a foe not a friend.

Evan Brand: Right. We really, really have the baby step in those cases so that’s why—

Dr. Justin Marchegiani: Totally. Yeah. I mean, just like you heal, with you know, food is medicine there, you go really slow and you do lots of things in broth form, in soup form so it’s – so it is so palatable. There is very little digestion that has to happen. And typically one supplement at a time and one nutrient at a time, titrate up from low to high. Even if it’s something that they can handle, if they go high dose, off the bat,   their immune system just freaks out.

Evan Brand: Well I wanna hit on something you just mentioned which is if we’re talking 1 to 2 years, it takes extreme patient—extreme patience for patients and clinicians because for us, that is a very intensive case for us to take on.

Dr. Justin Marchegiani: Totally.

Evan Brand: And you know, maybe this is to toot our own horns, maybe it’s just calling out the obvious that we do take the time, you know, with people we’re working  with. Sometimes it maybe 30-45 even an hour-long call for a follow-up just to take these baby steps. Whereas, let’s jus say some of the clinicians that we’ve seen out there, it’s too cookie-cutter approach and they don’t have the mental bandwidth or capacity for empathy to baby step this people.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So it’s here’s your cookie-cutter protocol, good luck.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Where with us, we’ve really, really, really gonna get super details.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And so this is why if you go and you buy like a leaky gut online program or some other type of program, and you get limited results and you get to us, we’re not gonna be surprised if you suffered through that, and you didn’t get a good result. Because at the end of the day, that’s why  Justin and I haven’t created  online courses at this point because it’s—it’s hard for us to sleep at night thinking that we’ve created a program that’s too cookie-cutter. We’ve really got to figure out a way that we’re gonna be able to work in all the minutiae and the small details and the variations—variation A, B and C, D for different people.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So if someone uh—packages something up all beautiful and says, “Oh, it’s $297 and all your problems are gonna be healed.” Uh—please be a little bit skeptical  of that.

Dr. Justin Marchegiani: I agree. And I’ve talked to you about a patient that I had today that email in that was dropping out of care. And we try to always set realistic expectations. This person just had her labs reviewed a month or two ago, and had multiple parasitic infections, severe adrenal dysfunction, HPA axis dysfunction, and then a lot of issues on her organic tests. Uh— detoxification issues, mitochondrial issues, and we just started with simple adrenal support, made diet and lifestyle changes and she had some— some side-effects so we try to cut things down, go slower. And we’re gonna kinda reconvene and work on supporting detoxification, but person had dropped out. Now, the problem is, to have expectations that things will work off the bat when so many things are wrong like that, expectations are incorrect. So  a lot of people they have preconceived notions even if you spell it out to them and you let them know, “Here’s where we’re at now, here’s where we’re going.” They forget because they—they want it done now. And they think because things didn’t work in that initial uhm—in that initial experience, that there is no way to fix it. So continuing to harp on patients in managing their expectations, even though they have a lot of stuff they’re projecting from past failures, we kinda have to get through it. Make sure expectations are real and that make sure they know, “Hey, here’s where we’re going now. Here’s where we’re going next.” These things ahead that may have to be dealt with for us to really see great changes.

Evan Brand: Yup. Well said. We got another question here.

Dr. Justin Marchegiani: Let’s hit ‘em.

Evan Brand: Let’s hit Steve’s question. After all GI infections are eradicated, how long does it take the gut to fully heal? All my infections are gone, but I’m still dealing with IBS, leaky gut and issues after H. pylori.” I’m gonna hit on this first Dr. Justin Marchegiani, if you don’t mind.

Dr. Justin Marchegiani: Yup. I know you’re gonna say it, by the way.

Evan Brand: Okay. So – haha if—

Dr. Justin Marchegiani: If you say it—If you say it, I’ll—I’ll tell you that.

Evan Brand: Okay. Alright. Please. Alright. So here’s what I’m gonna say. You say all your infections are gone, but you’re still dealing with IBS, leaky gut, and issues, I would like to know what test was this that says all your infections are gone because I bet all of your infections are not gone.

Dr. Justin Marchegiani: Yes! Whoo! I knew it. Yeah. You’re totally right.

Evan Brand: Haha

Dr. Justin Marchegiani: Yeah. You’re totally right. And then also, just making sure that you have the digestive nutrients on board to help heal the gut lining and the digestive support to break down the food and then I would make the food more—more palatable right now. I’d be looking more at the GAPS or an SCD or more of a soup or broth approach that makes the food really easy to take in. No raw veggies, uhm—try to keep it really palatable so the body can access it without much stress.

Evan Brand: Alright. So the beauty of the Internet, Stevie says—Stevie replied and he says, “DRG” Well, uhm— Justin–

Dr. Justin Marchegiani: It’s missing a lot of them. It’s missing a lot. You gotta do the DRG with the GI map. I a—I never do the DRG by itself for the most part—always both. You gotta do both.

Evan Brand: Yup.

Dr. Justin Marchegiani: And if there’s still an issue with the DRG and the GI MAP, I want them go for the  41 side-by-side.

Evan Brand: Yup. Agreed. So, Stevie, not that—you know, we’re not diagnosing you. That’s not what these calls are for. But, hey, Justin and I have seen a lot of false negatives with DRG and some other test out there. So potentially some stuff going on. And I would like to add a couple of points about like the—the issues, the leaky gut type stuff. You know, make sure you are doing some of the easy supports, too. You know, chamomile is great. You can do chamomile in a supplemental form. You’ve got chamomile teas, uhm—you’ve got L- glutamine. So there are some leaky gut supplements that why your til—still trying to figure stuff out, you can still be taking support of nutrients in the meantime while waiting for retest.

Dr. Justin Marchegiani: Absolutely. Totally. Let’s hit  the uh—last question there by—E Center Riley. See here, just diagnosed with Hashimoto’s, TPO and TGB bodies, 465 is that high? Eliminated the foods, gluten, dairy, soy, balance in blood sugar, hard with 5 kids. What should I focus on next? So 465 is definitely high. The LabCorp reference range for TPO is 34. Anything 34 above is considered positive—I think it’s above 34. 34 below is considered positive. And anything about 20, for me, I considered to be subclinical. So that is high. Anything above or around 500 is definitely high. I’ve seen patients at 2000, though. I’ve seen patients that go from 2000 to below a 100. Now, my goal is to get people—If I were you, I’d like to see a 70 to 80% reduction in that. Again, maybe you were higher before you made those changes. So I’m not sure if it was  gluten, dairy, soy. That stuff was cut out and then you saw the drop. But either way, uhm—getting enough selenium in there, 400 micrograms of selenium, addressing the underlying infections, things like H. pylori, Blasto and Yersinia can be coming to increase the antibodies. And then making sure the adrenals are looked at. There’s a strong adrenal-thyroid connection and a lot of people who have thyroid issues also have adrenal issues. And remember, TPO is a microsomal or essentially it’s uh—intracellular microsomal antibody that helps bind the thyroid hormone together. So if you’re making antibodies to that, it’s gonna prevent that thyroid hormone that I—Iodination process from occurring. So making sure we have the adrenal support there because the adrenals help produce cortisol. Cortisol is an anti-inflammatory that’s gonna help with the inflammation. And with the TPO there uhm—you could potentially have increase in hydrogen peroxide, especially if there’s small amounts of iodine getting in there. So get them the selenium will help neutralize that hydrogen peroxide into H20. High quality H20 which is uh—not gonna be as inflammatory.

Evan Brand: Well said. Yeah. And so uhm—Isabella Wentz, I just did podcast with her a couple of weeks ago. Actually that was my last uploaded episode. And uhm—we’re talking about bacterial infections, too. So you mentioned some of the parasites and she’s seen the same thing the parasite but also the bacteria. The Klebsiella, the Citrobacter, and all these autoimmune triggers has been bad guys for uh—these Hashimoto’s situations and these antibodies, so—

Dr. Justin Marchegiani: Yeah.

Dr. Justin Marchegiani: So, look for the bacteria, too, and you can definitely fix this stuff and you can make significant progress.

Dr. Justin Marchegiani: Absolutely. I mean one person here, wildlab access, “How do you test for various enzymes?”Number one, if you have gut stress, you probably have low hydrochloric acid. And if you have low hydrochloric acid, you probably have low enzymes. Why? Because hydrochloric acid is important for acts of—for converting pepsinogen to pepsin which is the proteolytic enzyme. Hydrochloric acid lowers the acidity of the chyme, which is the mixed up food in the intestine. That inten—that food that chyme that goes into the small intestine which the acidity then triggers the pancreas to make bicarbonate, it also triggers CCK that then caused that the gallbladder to produce bile that also stimulates the pancreas to make light based trypsin and chymotrypsin and all the enzymes that come down. So if you have enzyme issues, you also have hydrochloric acid issues, but we can also assess it by looking at enzyme markers, like elastase, too, which will uhm—look at that in the DRG or the GI MAP test.

Evan Brand: You better get that frog out.

Dr. Justin Marchegiani: Frog out. It just attacked me, man. I’m like, Ugh—

Evan Brand: Alright.

Dr. Justin Marchegiani: My water—so uh—yeah. Elastase, I think it’s elastase 1 is the enzyme marker we typically look at for uhm— low enzymes. But typically, just assuming that we have digestive stress, let’s assume it for sure.

Evan Brand: Yeah. I mean that’s the same—the same answer that I would say for the leaky gut. I had people say, “Oh, can you test me for leaky gut?”  It’s like, “Yeah. We can go to Cyrex and spend 500 bucks if you want to, but based on your symptoms, I guarantee there’s intestinal permeability. You’ve got XYZ. And we can—we don’t need to spend the 500 bucks on that test. Save your money for the organic acids, your comprehensive stool panels, the GPL-TOX, maybe heavy metal testing. Save your money for that stuff that you can’t really guess on.

Dr. Justin Marchegiani: Yeah. Absolutely. I agree, man. Well, anything else you wanna hit off the bat here? I mean I think—I had some really good successes last week, too, with some patients that had chronic pain, chronic mood, chronic energy, hair loss. And I mean—just really simple things. We—we fix their hormones, this person has autoimmune thyroid, uhm—hypothyroid as well. T3 was super low, it was uh– T4 to T3 conversion issue, dysregulated cortisol. They had a lot of malabsorption and they had a couple of infections and we just—we just took them down the map. An then just everything first time around, uhm—just knocked in place. I mean it’s like you swing the bat once and it’s connected. It’s gone. Those were the patients where its like, “It’s just so rewarding coz it’s just—it’s easy” And then you have  some patients where it’s a lot more trial and error and digging in. So it’s nice to have those home runs every now and then.

Evan Brand: Oh, man. I—so I had a home run earlier with this guy that I got off the phone with name Dion. And he was on an inhaler. An asthma inhaler.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And also I believe he was taking uh—allergy medication, like a prescription allergy medication.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Maybe it was one or the other. He alternated or he was on the inhaler something. But he was on prescriptions for allergies. And all we did is we cleaned up the diet, we’ve addressed some gut infections. He had candida and I believe a couple bacterial infections. I don’t believe he had parasites. I have to look back. But I remember a couple of infections, fix the gut, uh—supported adrenal’s basic adrenal support, some adaptogens. And I talked with him today and he said, “Evan, I’ve not used my medication in the last six weeks. And everything is blooming here right now. All the trees and plants and everything are blooming and normally, I’m debilitated. He said, “I’m completely fine.”

Dr. Justin Marchegiani: Isn’t that awesome?

Evan Brand: How in the world just by working on the gut and adrenals am I not allergic to the environment anymore? It’s just like, “Oh, it makes me feel so good.”

Dr. Justin Marchegiani: I see that all the time, too. And hydrochloric acid is one of those things that’s really great with allergies, too. You notice that?

Evan Brand: Ain’t that weird? I mean since digestive enzymes, I told him, I said, “Man, we’ve gotta keep up digestive enzymes.” And then actually I am gonna send him a bottle of some of the like natural herbal anti-histamines, just in case. Because he started sneezing on the phone. I’m like, “Whoa, maybe you’re not all the way out of the water yet. Have this on hand, in case you need it.” So the coresatin in, the rutin, some of those–

Dr. Justin Marchegiani: Hesperetin

Evan Brand: Yeah.

Dr. Justin Marchegiani: The things I love for allergies: number one, just really get a good air filter. I used one by Advanced Air. You can see that at justinhealth.com/shop Look at the approved products. I like it. It’s good. Uhm—and then your natural anti-histamine degranulating compounds. In my product, Aller Clear. Stinging Nettle, coresatin, and then you’re gonna have like some vitamin C in that, some potassium bicarb as well. So those are really good. And you can go up to eat. The nice thing about it, just not gonna be drowsy. So you can get that allergy support without getting the drowsiness and then really make sure the diet is anti-inflammatory. Up the hydrochloric acid because HDL is really important with low—with allergy. It’s gonna make a big difference.

Evan Brand: Yup, Yup.

Dr. Justin Marchegiani: Ginger. Ginger is phenomenal, too, for allergies. Really good.

Evan Brand: I love ginger. So it’s a great nutrient. I’d do teas, ginger kombucha, there’s so much you can do with ginger.

Dr. Justin Marchegiani: Oh, yeah. By the way, right after this, I’ve got a new grill. So I’m gonna go out, I’m gonna grill some grass-fed hotdogs, right? And then I’ve got some sauerkraut with mustard. And I’ve got a nice ginger kombucha, I’m gonna open up. So I’m really excited for my lunch break today.

Evan Brand: Nice. What kind of grill? Is that one of those  pellet jobs?

Dr. Justin Marchegiani: I actually—I got a new Webber just because it’s—it’s—my other one was 10 years old. And then the knobs are starting to go. So I got a nice, little Webber Spirit. So it’s great. It’s got three burners. Love it. And uhm—I got a smoker that I use sometimes for ribs on the weekend just like a 4-hour job. So it’s good to have a day or an afternoon to kinda be at home to enjoy that one but—Yeah. So love my grilling. Try not to get things charred. Try to keep the heterocyclic amines and the polyaromatic hydrocarbons to a minimum.

Evan Brand: Agreed. Agreed, man. Cool. Well I don’t have one on my end.

Dr. Justin Marchegiani: You wanna have a share?

Evan Brand: No.

Dr. Justin Marchegiani: Hope you guys are liking these calls here. We wanna do more. We wanna connect with the listeners. Our purpose really is to serve and help people get their health back. If people want more feedback, or want more kinda like rolling up the sleeves and specifically diving into your case, go to notjustpaleo.com or justinhealth.com, click on the schedule buttons. And we are here to help you out. Evan, anything else, man?

Evan Brand: That’s it. Have a great day people, drink clean water, get rest, reduce stress, be grateful. It’s gonna go a long way.

Dr. Justin Marchegiani: And people on Facebook, I’m hoping we can get Evan on here soon. We gotta just  figure that out. So hopefully, soon we’ll do that. So Evan, great chatting with you, man. We’ll talk soon.

Evan Brand: Take Care. Bye.

Dr. Justin Marchegiani: Bye.

 


References:

https://justinhealth.com/products/aller-clear/

https://justinhealth.com/products/advanced-pure-air/

http://catalog.designsforhealth.com/IB-Synergy-60

EFT.mercola.com

notjustpale.com

http://notjustpaleo.com/227-dr-izabella-wentz-hashimotos-protocol/

Dr. Ben House – Enhancing testosterone and improving your health- Podcast #130

Dr. Justin Marchegiani welcomes his special guest Dr. Ben House, a functional medicine doctor based in Costa Rica who also works with a lot of athletes. Join them as they engage in a very stimulating discussion about boosting up performance athletically as they focus on the role of testosterone in the male body.

Gain valuable insight about the recent researches related to Dr. Ben’s area of expertise. Know about the different tests, markers and treatment approach that he uses to address his patients. Get to apply some valuable information related to effective movement patterns that might be related to your health and body goals.

In this episode, we cover:

2:35   Nutrition Recommendation

9:40   Overtraining and Cortisol: Testosterone Ratio

13:33   Functional Medicine Tests for Athletes

18:37   Steroid and Insulin Use

33:30   Movement Patterns

42:40   Blood Markers and Patterns in Athletes

 
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youtuve

 

 


Dr. Justin Marchegiani: Hey, there! It’s Dr. Justin Marchegiani. Today we have Dr. House in the house. Dr. Ben, how are we doing today, man?

Dr. Ben House: I’m doing great. How are you?

Dr. Justin Marchegiani: Excellent. We got you on Skype, too. So anyone listening to the MP3, feel free and click below and check out the YouTube channel as well. And Dr. House is over at functionalmedicinecostarica.com

Dr. Ben House: Yeah, that—that’s me. That’s where I’m at.

Dr. Justin Marchegiani: And you’re seeing patients virtually, as well, which is great. So if you feel like you jive at Dr. Ben, feel free head over there and reach out to him. Dr. Ben is also a PhD grad over at UT. Hook ‘em horns, baby. I’m in Austin now, too. So I’ve given up my Boston College UMass. I’m a modern now. And UT Longhorns, baby. So, congrats on that. Excited to chat.

Dr. Ben House: Yes. I miss Austin. It’s an amazing city for sure.

Dr. Justin Marchegiani: It is. And I know you used to work with a lot of athletes. Were you working with the UTF-8 as well? And the football players and such?

Dr. Ben House: Uh – I worked on a time, right, in basketball.

Dr. Justin Marchegiani: Basketball.

Dr. Ben House: Uhmm – Yeah, yeah. So now he’s in the Philadelphia 76ers. So I consult with couple of proteins but uhmm—it’s—yeah, I primarily work with males and athletes.

Dr. Justin Marchegiani: So tell me a little more about that. Like what are some of the low hanging fruits mean? Maybe we don’t have a lot of professional athletes listening here today. But what are some of the low hanging fruits are, you know, average people are listening can take and apply to themselves to make them better athletically?

Dr. Ben House: I think a lot of times we put professional athletes on the pedestal.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But most of the time, professional athletes are—uhm—they’re successful in spite of what they do.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Because of what they do.

Dr. Justin Marchegiani: Totally. So it’s probably not best to look at what they’re doing. Uh—uh there’s obviously exemptions to every rule. There are really some teams that are really pushing the envelope as far as nutrition. But you gotta think in the pro circumstance, there’s not a ton of motivation and drive to get guys healthy if it doesn’t get them performing.

Dr. Justin Marchegiani: Right.

Dr. Ben House: Uhmm—so kinda sell there is—is Dr. Bob is really good about this—it’s you’re selling longevity.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Coz can you—after someone’s thirty, can you give him 10 years in the league, right? And that’s—that’s pretty important. And so, if we take this to the weekend warriors,  someone who’s—who just loves to train like me. I’m not a professional athlete.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: I played college football, but after that, the dream was dead.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uhmm—And so it’s—it’s we really gotta—I think the low hanging fruit is the fundamentals—the things that we always talk about. Coz most athletes—they—they don’t—they overtrain because they’re under recovered.

Dr. Justin Marchegiani: Totally. Totally. Now on the diet side, that’s probably a foundation. I think you’ll agree with this. On the diet side, are you kinda following the paleo template? What is the food quality? What does the macros look like with an athlete like that?

Dr. Ben House: So when I lecture on or talk about nutrition, I always talk about three things. So we have quality is the first thing for me. Quality is super important. Uh—we have quality in there, we have timing.

Dr. Justin Marchegiani: Totally.

Dr. Ben House: Those are kind of—For me those are in the order of importance. Uhm—but we have to be really careful. Like Michael Phelps.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Who probably eats 68,000 calories a day.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: You obviously can’t eat brussel sprouts and sweet potatoes and get it done. Uhm—so when you have—when you have some who’s just training 20 hours a week, your quality has to drop. And you have to make sure your adjustment’s on point as well.

Dr. Justin Marchegiani: Totally.

Dr. Ben House: Coz otherwise you gotta just stop, put the car in the garage, and really kinda figure it out. And so it’s—we’re at a really cool point where I think we have some technology coming out where we can just individualize.

Dr. Ben House: So all these—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: –hypothetical, best way shit can just go away.

Dr. Justin Marchegiani: Totally. So we got the basically, high-quality proteins, high-quality fats. They’re probably—maybe these guys are gonna be higher on the macronutrients with the carbs and such, correct?

Dr. Ben House: That all depends – So carb work—

Dr. Justin Marchegiani: And in sport maybe.

Dr. Ben House: The carb world is really—there’s—I think of carbs as n__

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: And so if—if you want somebody to go fast, you need carbs and glycogen assistance. And so you can’t—you can’t feed high-intensity exercise on fat. It’s—it’s—

Dr. Justin Marchegiani: Right.

Dr. Ben House: We know that if your fat adapted, you’re actually—you’re actually metabolically inflexible so that you can’t burn carbohydrates at those—at those faster intensities. Uhmm—so for me, it’s all about what is athlete doing. What if they’re, you know, 40 year old, strength athlete and they’re 20 pounds overweight, uhmm—I’m gonna stay at the 5 rep range. Probably knock down carbs pretty well. If—are they a 20 year old athlete who’d never had any problem with weight, and I got their blood sugar, all looks fine, I’m gonna—how many carbs do you take, right?

Dr. Justin Marchegiani: Got it. Okay. Alright, got it. So we have kinda the macronutrients, we’re obviously cutting out—organics gonna be obviously dialled in, right? Food quality’s gonna be dialled in. We’re eating enough calories—that’s big. We’re mak—making sure the in the HCl and the enzymes are up to snuff so we can actually break down and digest those foods. We’re making sure we’re drinking, we’re sleeping maybe 8-10 hours. That could be big thing as well. Uh—more exercise, more muscle breakdown requires more recovery. I think with Steve Nash and Tom Brady, too. I mean they get like 10 hours sleep a night. I think that’s the biggest thing. Huge.

Dr. Ben House: Number one. Like if you wanna increase performance, like this is out of  Stanford, like sleep more. Spend more time in bed.

Dr. Justin Marchegiani: Yeah. You get to bed between 10 PM and 2 AM and you’re asleep during the cycle. You’re getting access to maybe $3,000 to $5000 of growth hormone a month just by getting in bed during those timeframes. Would you agree?

Dr. Ben House: Yeah. And I mean, testosterone is also secreted. GNRH works in that—inside that time block, too. So it’s—the circadian rhythm hormone. So you start jacking up your circadian rhythm. And a lot of the—one of the probably because athletes we see, they’re just hooked up on cell phones all the time like this is perpetual, you know, Twitter, Facebook, social media feed. Man, that’s—that’s a whole lot of bull S.

Dr. Justin Marchegiani: Yeah. Totally. So you get the nutrients, you get the digestion, you get the right amount of exercising. That’s a really key thing coz a lot of times it’s train, not drain. And you see a lot of overtraining with your athletes?

Dr. Ben House: Well, I think we have to be mis—I come from a strength coach background. So in the college setting, the strength coaches it—it’s unfortunate. And you even saw it at the  University of Oregon.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: When they got rid of radicals who was like, “who’s the man?” Uhm – and I bump into this other guy and he started smoking people and he put three guys in the hospital. Uhm—so the saying with this coach is pri—it’s sometimes they’re thought of as the punishers. So they have to dole out like someone doesn’t show at the practice. And so, if you’re in a team sport atmosphere, like—you don’t have that much control over the overall, though. There’s some people that are using like Zephyr or some really cool GPS program to over—to like measure overall look.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uhm—but some of that is outside of your control.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: The cool thing—in the general population and if you have—while like private is because you can have total control over the athlete.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And—one of my favourite examples is Rutherford who like—he was like the 200 best in the world. Uhmm—and now, when he—he was training like typical like four days a week. And they brought him to like one-two hard training sessions every 10 days, and he won the gold medal. Alright. So—

Dr. Justin Marchegiani: Wow.

Dr. Ben House: So it’s kinda—it’s like everybody is individual and so if you can individualize that protocol and—and volume’s a hammer, right? And so that’s not the thing sometimes that we wanna use all the time.

Dr. Justin Marchegiani: Right. Right. That totally makes sense. So when you’re exercising these guys, are the movement patterns gonna be standard for each person like the functional ones like squats, deadlifts, lunges, step up, like core pushing and pulling movements. How do you adjust those and tweak those with the sports with the athletes?

Dr. Ben House: I—So that’s gonna be all dependent on the sport, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And the position that they play. Uhm—so if you got a baseball player, like it’s all rotary power, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: It’s probably getting them—getting them at the right side of the right handed. Getting them kinda even and obviously not getting injured. from up your eyes standpoint.

Dr. Justin Marchegiani: Right.

Dr. Ben House: Uh—so—it, it’s so rare but I think for that, it’s also gonna depend. Like is strength, is arm strength really doesn’t apply unless like you’re a full-back or a line man. Uh—sometimes the best guys in the weight room are the worst kind in the field. Uhm—

Dr. Justin Marchegiani: Right.

Dr. Ben House: It’s uh—we have crossfit now. I think that’s kinda—that—it’s really cool. And now the weight room is the sport.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And so weekend—it’s open right now—we can do crossfit as much as we want. But I think it just produced some people that can take insane amounts of volume. Uhm—and not everybody can. And they get—It’s very Spartan type society.

Dr. Justin Marchegiani: Oh, totally. Now when you’re working out with someone, is there a certain heart rate that you want people to get back down to? Maybe with your adrenal dysfunctional patient, is there a certain heart rate you want to get back down to before they go into the next set?

Dr. Ben House: Uh—I’m kinda __heart rate isn’t our best.

Dr. Justin Marchegiani: Okay.

Dr. Ben House: It’s an okay marker.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: I—there’s a new technology that we’re using called mock C—

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: Which is essentially muscle oxygenation. So we wanna see that muscle is just resaturated with oxygen (O2).

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And it’s get—it’s probably not a horrible for just the average person right now.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But it will get more affordable, uhm—it will get more usable. Right now, it’s not that user-friendly. Uhm—I think you probably want to get back to a good resting heart rate. Also the—the research is pretty clear cut if you’re chasing hypertrophy. Uhmm—that 2-3 minute window for rest is probably where you wanna be.

Dr. Justin Marchegiani: 2-3 minutes. Got it. And are you looking at free cortisol to uhmm—I’m sorry, free testosterone to cortisol ratio to assess overtraining in any of your athletes?

Dr. Ben House: So I look at total testosterone. I don’t put a lot—this is my personal opinion—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: I’ve done a lot of research on salivary panels and I don’t like cortisol panels coz they’re just like—their—they’ve done 30 days of salivary test and they’re super variables especially in athletes. Uhh—so I don’t—If I could get a week of them, I would use them. But if I could only get one day, I don’t wanna just—I don’t wanna live and die by that one day. Uhmm—so, and I—you can ask questions. Like you know, probably the best indicator of overtraining is like hey, how you’re performing. Like how do you feel, how’s your mood like. So a lot of times, we can get a lot of information just by asking questions.

Dr. Justin Marchegiani: Got it. And what’s your total cortisol cut-off? Your total testosterone cut-off be like? Is it 100 above?

Dr. Ben House: Yeah. I mean the research is—I don’t really get, I don’t like the whole bench press number of testosterone.

Dr. Justin Marchegiani: Right.

Dr. Ben House: I think it’s only looking at production. We don’t know the sensitivity and the receptor. We—we can get such binding globulin and the albumin.

Dr. Justin Marchegiani: Totally.

Dr. Ben House: We can get free testosterone but I mean the ment—the mental strain of that for guys like, “Hey you’re inadequate, you have a testosterone of 5.”

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: I don’t like to do that.

Dr. Justin Marchegiani: Do you see correlations, though? Do you see like, “Hey, these are the althletes that are responding the best, that are recovering the best or getting the best results” Here is where his numbers at. Do you see any correlation there?

Dr. Ben House: Yeah. I think—we can’t really make that correlation—

Dr. Justin Marchegiani: Okay.

Dr. Ben House: inside of physiological ranges. Uh—we don’t have a lot of data on that as far as research. Anything I would say would be anecdotal there. Uhmm—do I think, do I have a hunch that it’s better to be at 800 than 380?

Dr. Justin Marchegiani: Yeah. Yeah. Totally.

Dr. Ben House: Do I know that 800 is better than 600 or 500? I don’t know. I haven’t seen that. I’ve seen—I’ve seen some beast that are in the 500 range like 10% body fat, like 210—like they’re front squatting 400 pounds. Like, so—

Dr. Justin Marchegiani: Testosterone can be really variable. I think it peaks more in the AM right? And they can drop down in the afternoon. It can be the variables. So you may just catch it at the wrong window.

Dr. Ben House: Yeah. And in some circadian rhythms are screwed up like you have no idea where you’re measuring. So, like it’s—it’s to me—it’s the lab value is not the person so I always wanna like, “Who is this person?”

Dr. Justin Marchegiani: Totally. Yeah. You gotta look at the clinical outcome along with the—the objective values. Totally makes sense. Are you doing any adrenal testing with your regular functional medicine patients?

Dr. Ben House: I don’t do a lot of adrenal testing. Uh—you interviewed Wakowski here, kinda one of my favourite sayings, like 99% of new-age primates are cortisol resisting or have cortisol dysregulation so—

Dr. Justin Marchegiani: Totally.

Dr. Ben House: To me it’s like why do I want to measure chaos? I’m a big fan of not measuring chaos. Uhmm—and that—that’s just my viewpoint. So I would be apt to use like—I would use it later.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: So if you’re sleeping, if you’re doing all the things that you need to do, then I’ll run that—if we’re still not getting what we need to do. But the other way you can kinda frame it, too, is well, if I put this—I try to make it as least financially kind of—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uh—

Dr. Justin Marchegiani: Yeah. You’re trying to make it that the buying financially is low as possible so you can help more people, right?

Dr. Ben House: Yeah. Yeah. But for the testing standpoint, so—if—if someone—if I don’t—if they don’t care about money, I’m gonna get this test coz then if I show them, right? Then they’re gonna have it buying.

Dr. Justin Marchegiani: Yeah. Exactly.

Dr. Ben House: Yeah. And lever is gonna be higher. Okay, your free testos—you’re free cortisol’s jacked. You have no DHEA. You start to do the shit that you need to do, right?

Dr. Justin Marchegiani: Exactly.

Dr. Ben House: Uh but if I can get that from other means, If I can them dialled in the fundamentals, then—and doing all the things that they need to do—coz nobody in the general population’s doing that. I mean slow—today is low.

Dr. Justin Marchegiani: Exactly. So looking like at the palette of test, functional medicine test that you’re using with your patient, with your athletes, what are those top tests?

Dr. Ben House: Uh, so I – my top 2 are definitely a comprehensive blood panel

Dr. Justin Marchegiani: Got it.

Dr. Ben House: And then CSA. Like uhmm—

Dr. Justin Marchegiani: Stool analysis.

Dr. Ben House: Yeah. And if someone doesn’t—if that doesn’t pop, maybe I’ll go grab a SIBO breath test or something like that if they have—if they’re carbon tolerant—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But we gotta immediately fix the digestive component. And obviously you don’t fix that without fixing the cortisol component. But uhmm—that’s my—that’s what I do. And then I’ll run precision analytics sometimes.

Dr. Justin Marchegiani: Yup. Okay. So you will do one of the—the drug urine testing for the adrenal rhythm sometimes.

Dr. Ben House: Yeah.

Dr. Justin Marchegiani: Okay. Good. I do those tests as well and their good.

Dr. Ben House: I want to see uh—so a lot of functional med—I think we can get in trouble coz I’m a PhD so I’m very research oriented.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: So if a test doesn’t have a ton of research behind it, I—I’m not very apt to use it.

Dr. Justin Marchegiani: Totally.

Dr. Ben House: And that can be good and bad. Uhm—but I think like 5 years down the road, like is that lab gonna run like duplicates for 30 days? Are they gonna—are they gonna just do everything in their power to validate that measurement? Or are they just gonna this is it. This works? Then that’s—that’s what I wanna see.

Dr. Justin Marchegiani: Yeah. That totally makes sense. And Biohouse got a new one out, called the CARS, the adaptive response. And they’re doing cortisol I think three times in the morning.

Dr. Ben House: Yeah.

Dr. Justin Marchegiani: And it’s interesting because you do cortisol right away, you do it an hour later, you do it two hours later, and you see a major change in that first two hours. So I think people are really getting more stringent on when you do cortisol especially in the AM which is helpful.

Dr. Ben House: Yeah. Our lab at UT actually did a bunch of stuff on the cortisol awakening response. Which is—which is—that’s kind of—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: You knew that’s oughta things go as well.

Dr. Justin Marchegiani: Yeah. I totally agree. Now looking at growth hormone, how does growth hormone interplay? Kinda potentiates the effects on testosterone? How does growth hormone interplay? I know it’s connected to IGF-I goes to the liver. How does that affect testosterone and basically when you put on more muscle?

Dr. Ben House: So—

Dr. Justin Marchegiani: I know it’s a lot—

Dr. Ben House: Testos—testosterone’s gonna feed in IGF, right?

Dr. Justin Marchegiani: Okay.

Dr. Ben House: A lot of times and we can get the liver obviously want to work—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: growth hormones gonna be secreted at night and then the liver’s clogged is not gonna make IGF. To me, we can— from an IGF perspective—I’m not super well versed in IGF because I work with a lot of young athletes. And I don’t think we’re gonna have a lot of  IGF problem, like IGF-1.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: I’ve never—I used to measure IGF-1 all the time and like no one was out—like no one was—everybody was kinda in range. So I stopped running it. Uhm—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And that’s just my take. Now, could they benefit from growth hormone? Probably, right? Uhm—but we also have to be careful with that because IGF-1 is a growth factor.

Dr. Justin Marchegiani: Yeah. It causes cancer.

Dr. Ben House: Yeah. And well the research on that’s kinda another thing HGH is not related to increase cancer risk but I think—I think the evidence there—is there—just a little bit caution especially if you have a lot of cancer in your fate. Uh—

Dr. Justin Marchegiani: Yeah. Totally. So basically, the big things to increase testosterone: sleep, protein consumpt—ad—adequate protein, I imagine, right? The right amount of stimulus and then how about the timing of nutrition? Where does the timing come in to really potentiate testosterone and growth hormone?

Dr. Ben House: Well, I don’t know if we have a lot of research on that. Like acute—acute feeding of either fat or carbohydrate will actually lower testosterone uhm—especially in the fasted state. So to me, the bang for the buck there is probably from and under recovered mechanism. So if you just crash your glycogen stores, you probably wanna refuel. Uh—in—we know the biggest thing is gonna be total energy intake. You drop your total energy intake by 15%, you’re gonna lose D3, you’re gonna lose testosterone, so getting—if—if someone’s not—if someone’s training hard, they need the—in my mind, they have a body comp issue. And they’re training hard, they need to eat as many calories as they can to maintain their weight.

Dr. Justin Marchegiani: So when you see these guys in the NFL, for instance, let’s say a linebacker that needs to be big, strong, but relatively lean and fast, is it really just the quality of nutrients and getting enough of it? I mean these guys literally eating two-three thousand calories   more than what they would need just at that height and weight to keep that mass on?

Dr. Ben House: Yeah. In season, like you’re gonna see—you’re gonna see insane amount of calories going and going on their mouth. Like—they—they have to. They are that active. They’re—like you have a 230-250 pound man, they need a ton of food –three to five thousand calories easy. And so uhm—that’s—you gotta be careful coz that’s hard to get. And if—and that’s why we can get into trouble like intermittent fasting with that athletes.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And Paul Quinn is like very, very against intermittent fasting in athletes. And — I—I’m—I’m in the same camp. Uhm—if you—body composition is completely different, health is completely different, but I think—especially in season if you have an athlete that—you gotta get—you gotta make sure that you get him first.

Dr. Justin Marchegiani: Totally. What’s your take on steroids in general? Using steroid and/or using insulin as well. What’s your take on that?

Dr. Ben House: I—yeah. Yeah. This is awesome. Uhmm—

Dr. Justin Marchegiani: Let’s do it.

Dr. Ben House: From a TRT perspective, I think we’ve—and—a lot, just like a lot—like marijuana and I say marijuana’s bad or good. Nothing is bad or good, right? It is all context.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uhm—I think we’ve had a veil dropped over our eyes as far as testosterone the same way.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: Uh—and everybody thinks their testosterone is very negative because of baseball, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But—the overall, the evidence for testosterone replacement therapy is overwhelmingly positive.

Dr. Justin Marchegiani: Right.

Dr. Ben House: Overwhelming. So—uh—now, we don’t want the same thing. We don’t wanna just slap that on every guy. We wanna make sure—we wanna use all these lifestyle strategies first, but traumatic brain injury—I – you know that’s gonna affect testicul—the—testicularitis. And so—And also, blaunt trauma to testicles. My best friend played __cross. He got hit by a 110 mile cross bow in the nuts. He had three concussions, right? So is that guy—

Dr. Justin Marchegiani: Aww, man!!

Dr. Ben House: Is that guy gonna be able to produce his own testosterone, right? And that’s not that abnormal like you talk—

Dr. Justin Marchegiani: Right.

Dr. Ben House: You talk—you talk to a lot of professional athletes like how many testosterone do you have?  I don’t know—right? Especially—especially in contact sports. Ask any of the guy.

Dr. Justin Marchegiani: That’s crazy. And elbo—also the xenoestrogen exposure is gonna disrupt LH- luteinizing hormone feedback loops, too, right? So we have the—we’re bombarded with the xenoestrogens and if you’re a female, obviously just in birth control pills will scrap the females as well. But you have it in the water, you have it in the pesticides and yeah—the plastics as well.

Dr. Ben House: Yeah. This is something like—male health—this is why I feel so strongly about male health is coz we have no idea what’s gonna happen, right? Babies—they—their PON1’s are not very active. And PON1 is that enzyme that kids rid of persistent organic pollutants, right?

Dr. Justin Marchegiani: Totally. Yup.

Dr. Ben House: And so we got—30—the top 37 pesticides that are used in our foods are anti-androgen.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: So we have no idea what’s gonna happen, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And then so the—and they only run test on one of them. They don’t run it at all of them. Uh—it’s—it’s very scary. Uhm—and this is—from my protecting you have to do everything in your power to eliminate all of those potential pollutants, right? Skin care products, everything. So we gotta get kinda weird. Uhm—and you don’t know if that’s gonna have an effect but you have to—you have to make sure. You cannot—especially babies. Like we cannot put that on—Look at the male population it’s going up today like it’s pretty scary.

Dr. Justin Marchegiani: Oh, especially if you—you can’t breastfeed your child and you’re feeding them soy protein isolate. My god, the phytoestrogen content that you’re getting on that can rise up to potentially a birth-control pill in amount. Especially that’s all they’re relying on for the first six months to a year.

Dr. Ben House: Yeah. It—it’s wild, man. Like it—it’s—it’s gonna be—it’s gonna be really, really interesting as you see what happens in 30 years. Like when this generation gets so like their 20’s and 30’s and 40’s, it’s gonna be—it’s gonna be wild.

Dr. Justin Marchegiani: Absolutely. I have some people here in Austin, they’re uhm—doing some run care in melatonin and I’m researching helpful companies that’s more essential oils and more natural compounds and reusing like dying to meet—dying to make just earth to treat the fire ants or using boric acid for natural things. And peppermint oil for the Hornet’s and vinegar for different things. So we’re trying to limit our load naturally. But I see people everywhere else they’re putting a lot of chemicals out there. Are you familiar with the research on lung care products and like childhood lymphomas and leukemias and such?

Dr. Ben House: No. I haven’t—Well I haven’t looked at a lot of that research coz that’s not in my wheelhouse.

Dr. Justin Marchegiani: Got it.

Dr. Ben House: But if you look at people just eating organic vs. non-organic p—produce like if you eat organic produce, you’ll get higher sperm count—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Your sperm is clear. It’s hard—that’s the dopest study at Harvard Med.

Dr. Justin Marchegiani: Yeah. Yeah. I totally get that one, for sure. I’ll plug the documentary, too. The disappearing male.

Dr. Ben House: Yeah.

Dr. Justin Marchegiani: Excellent PBS documentary that talks about basically these estrogenic compounds in the environment that are hurting men and our future babies. So, keep that mind, too. That’s really good.

Dr. Ben House: You can kinda educate me on this, but I think all of those are gonna be mitochondrial toxin-based, right? If you jack up the mitochondria, you’re gonna have trouble with cancer.

Dr. Justin Marchegiani: Oh, absolutely. You’re gonna have issues with cancer. There’s a great book it’s called, “Tripping Over the Truth”. That’s a really good book on cancer and the connection with the mitochondria. That’s a really, really, good one. And also, just the fact that it affecting the HPT access coz you screw up LH, uhm—you screw up the pineal gland, that affects melatonin that affects puberty. All these things that antagonizes itself. And then the more fats cells you have, the more estrogen you produces, then it’s a downward cycle, the more insulin-resistant you become. And it’s just this downward cascade—this metabolic accident, so to speak.

Dr. Ben House: Yeah. It’s just loops everywhere. And you gotta figure out how you’re gonna break those loops and—and that’s the thing, some guy, they have like 25 loops right in. And you just wanna give them to—that’s not gonna fix the problem. You have—That’s not—you’re not helping anyone.

Dr. Justin Marchegiani: Yeah. And what about things like anabolic steroids? The more synthetic ones? DBOL and such?

Dr. Ben House: Yeah. I don’t use those. Uh—I have clients who do. Uh—

Dr. Justin Marchegiani: Yeah. What’s your take on that?

Dr. Ben House: I don’t—I don’t manage any of that.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: What I do is I just wanna make sure that—that’s their choice, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: So I—as a—as a—as—just a male in general and as a clinician, I don’t ever wanna change someone’s goals. I just wanna help them do what they do better. And so, if you wanna be a pro body builder—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: You’re gonna have to play in that realm. Now I’m not the guy to run your anabolic regimen. But I can at least see like what’s going on? Are you—are you able to get rid of it? What’s your liver doing? How’s the hematocrit? Can manage all the things that could go wrong in that situation? 24:33 Uhm—the research on that is—is—is—is I think one thing that I would like to highlight—so they’ve done studies where they give a guy 600 mg a test.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And the average builder like 1100, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And so they give these guys 600 mg a test in 12 weeks. They give 20 pounds a muscle without an exercise regimen.

Dr. Justin Marchegiani: Whoa!

Dr. Ben House: Yeah. So you’ll think about—

Dr. Justin Marchegiani: That’s insane!

Dr. Ben House: You’ll think about like instagram phenoms, like you got a lot of people out there—a lot of males that I think are chasing things that aren’t physiologically possible. Uhm—and that—

Dr. Justin Marchegiani: You mean—

Dr. Ben House: Yeah. Go ahead.

Dr. Justin Marchegiani: You mean like the people you’re seeing align, they’re doing those things that you mention. The 600 mg of tests and they’re just getting massive amounts of muscle that you may not be all to cheat naturally. Is that what you’re saying?

Dr. Ben House: Yeah. The ethotomy is uhm—so that’s a—that’s a calculation that you can do. And anything above 25 is—it’s kind of—then you start asking questions.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Like my ethotomy is like 24, right? And I’m, you know, 1—190-185-190 and anywhere from 8-11% body fat. Maybe a little bit more if I’m off my game. Uh—and so there’s kind of a line in the sand that we can cross naturally. And obviously there’s gonna be people that are above that just from a statistical perspective.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But if someone just looks on godly jacked, I mean maybe—well—who am I to say what they’re doing and I don’t wanna be the guy that’s the ultimate whistle blower.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But I think we just gotta—we just gotta—when you look at everyone else’s highlight here, you’re gonna start questioning your own self-worth and I don’t know that you wanna do that.

Dr. Justin Marchegiani: Totally. Totally. And what do you think about uhm—tendon growth when you’re on hormones like that? Let’s say, I know more of the artificial, but in general, do you get the compensatory growth in the tendons to support the increase in muscle mass?

Dr. Ben House: Yeah. So that’s one of the problems, right? It’s uh—you think about how the body responds like to__

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: The first thing that we’re gonna have is neural, right?

You can get that in minutes. And the second response is muscular. And so that’s gonna take, you know, 8 minutes, maybe last if you’re—you’ve never__

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But that—that collagen response that you know, that’s building up the fascia, building up all the tissue and the bones. That takes a longest time. So when you take shortcuts, if I put a 25 lb muscle on you, and I haven’t—I haven’t build up the structure, I’m gonna—that’s when you like—biceps tear don’t happen. Like you see a bicep tear on a deadlift, like, “Uhmm” I’m thinking, what’s going on?

Dr. Justin Marchegiani: Yeah. Totally. So do you uhm—

Dr. Ben House: Does that make sense?

Dr. Justin Marchegiani: Yeah. That totally make sense. So you—something you’re careful of and you increasing collagen supplementation to help provide extra tendons building blocks, too?

Dr. Ben House: Well, everybody had—everybody is pretty much using that I have is collagen protein.

Dr. Justin Marchegiani: Great. So you’re doing that.

Dr. Ben House: Yeah. Especially in the beginning, I take everybody off away for 30 days just coz it’s a common allergen.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And if they can handle that, I want it back in. Uhm—but yeah—yeah I would say that’s kind of a non-issue for me.

Dr. Justin Marchegiani: So you sub out—will you sub out like the way for like a high-quality, hypoallergenic pea protein in the meantime?

Dr. Ben House: No. I’ll use—I’ll use uh—

Dr. Justin Marchegiani: Beef?

Dr. Ben House: I think if you take enough pure paleo, I think you’re gonna be fine on losing content.

Dr. Justin Marchegiani: Got it.

Dr. Ben House: That’s like a 3-gram threshold. So yeah, less than whey but if you take 30-40 grams of it, you’re gonna be fine.

Dr. Justin Marchegiani: Nice. Awesome.

Dr. Ben House: Well, I know you post a lot on Facebook. You got a home gym, you’re dad in Costa Rica now, you move from Austin down there. So you got a pretty awesome lifestyle going. Give me a quick walkthrough in the day of a life of Dr. Ben. What time do you get up? What do your meals look like? What does your work out looks like? What is post and pre work out nutrition look like? What does sleep look like?

Dr. Ben House: Yeah. That—that’s fun.

Dr. Justin Marchegiani: Ahaha.

Dr. Ben House: So my days, I wake up—one of the cool things of why I’d wanted to move here is getting closer to the equator.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: Uh—So I go to bed like 8:30. Can’t keep my eyes open.

Dr. Justin Marchegiani: Wow!

Dr. Ben House: And then I’m up naturally like you talk about cortisol awakening response, like I can’t sleep past 5:30. So—

Dr. Justin Marchegiani: That’s great.

Dr. Ben House: So I wake up—I wake up and I immediately sit, right? So I sat for—I meditate for 15 minutes. Done that for years. Uhm—

Dr. Justin Marchegiani: Great.

Dr. Ben House: Never—never will stop. That’s kinda—

Dr. Justin Marchegiani: Any kind of meditation? Just kinda like a blank slate in the head and you’re breathing or—

Dr. Ben House: I use mantra practice. Sometimes my dad is a—is Zen teacher.

blank slate and had new breeding or is much about is sometimes my dad as it is in Zen teacher is an ordained Zen priest.

Dr. Justin Marchegiani: Oh, awesome.

Dr. Ben House: Yeah. So in—I started—I took my whatever you wanna—I’m kinda involved when I was about 19. Uhm—probably the best gift that I was ever given uhm—was that to be able to go to that—come to that mindful practice early.

Dr. Justin Marchegiani: That’s great.

Dr. Ben House: So I’ll do—I’ll do some calming. Sometimes I do some Tibetan practice which is like—it’s one of my favourites where you wish someone well that—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And the next breath, you wish someone well that you’re kinda apathetic about.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: someone that you don’t know very well. And the last, you wish someone well that you hate.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: That you don’t really like.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And it kinda—it really helps you and by the end, you’re kinda like, “Man, I don’t have that many people that I—that I don’t like and why I don’t like them.” It becomes mostly probably, you know, you start looking to word about that.

Dr. Justin Marchegiani: Totally.

Dr. Ben House: That’s one of my favourites.

Dr. Justin Marchegiani: Love it. That’s great. So morning routine, you’re getting up 5:30, you do your meditation 15 minutes, what’s next?

Dr. Ben House: Uh—so if it’s a training day, I’m probably gonna have some type of easily digestible carbohydrates and Natchan in the morning coz it’s hot here. Uhm—also, I train in I’d—I like to smash myself with prob—I’m NEAT head, there’s no way around it like I’m gonna be that guy probably even if—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: ills me. Uhm—And so I’m—I’m working that glycolytic high intensity pathway uhm—3x a week. In my youth, I do it unbelievably too much, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But—so I’ll do that and I’d work for about 3 hours in the morning depending on what I got. I usually don’t take clients until the afternoon. Uhm—And then I’ll train or if it’s a non-training day, I’m just working. Uhm—and then right now, we’re building a retreat center so I have a lot of things that I—I’m the gen—I’m essentially the general contractor there so—

Dr. Justin Marchegiani: That’s awesome.

Dr. Ben House: And so half my day is in Spanish, the other half is in English. Uh—sometimes I have to run up there and do stuff but—

Dr. Justin Marchegiani: Nice.

Dr. Ben House: I spend—I spend 4 hours at least a day on Pub Med in researching and writing. That’s my—that’s my thing. I love it.

Dr. Justin Marchegiani: And you have awesome Facebook posts, too. I appreciate it. You really condense a lot of the research down.

Dr. Ben House: Yeah. I think that’s how we move people, right? We just consistently hit them. And you do it with a podcast.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Like this is a—even if it’s—even if it’s repetitive affirmation like if it produces an action, that’s what I’m all about.

Dr. Justin Marchegiani: Totally. Got it. So Pub Med 4 hours a day, that’s awesome. And then patients and then what’s next after that?

Dr. Ben House: I try to stop working.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uhm—I think a lot of us are super passionate about our craft. I’m better about that when like something isn’t coming like I have uhm—big—big presentation’s coming up in a month. So now, I’m kinda—I’m always prepping for that. Those are kind always in my mind. So I use a lot of hard mat to kinda like turn my self-doubt.

Dr. Justin Marchegiani: Yup. Yup.

Dr. Ben House: Uhm—And I try to shut it down. Shut it down in the evening, definitely by 5 or 6. And I’ll just do fun stuff with my life, right? Maybe we’ll read. Maybe I’ll read something like super unscienc-y. Maybe we’ll just watch a movie. We kinda watch— I tend to push for comedies. He tends to push for dramas but uh—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And I always make sure—one thing I’m really, really like big on is you have a treadmill test. It’s just baseline of movement. Like—

Dr. Justin Marchegiani: Huge.

Dr. Ben House: We put all these—we put all these pressure on exercise and it’s just a small bucket as far as like movement. It’s like NEAT is where it’s at, Non Exercise Activity Thermogenesis. And so if someone is not gaining 10,000 steps in a day, like all of the core can take can be just regulated. They’re not gonna be able to sleep. So so many good things happen if people just move.

Dr. Justin Marchegiani: Oh, I agree. I mean I just got seen patients yesterday. I’ve got 25,000 steps yesterday. I mean I walk about 10 miles a day. I’m on my leg uh—my fitness power here. And I’m like—you know, there’s a leader board section and I’m always like—I always like try to be number one. So there’s yesterday right there, 21, 500. So, super. I love it.

Dr. Ben House: You’re living it.

Dr. Justin Marchegiani: Oh, yeah. Absolutely. And then the key thing is to I kind have my kettle bells down over here and then some push-up bars so I try to rep some of the that stuff in between patients even if I can do 2-3 minutes in like 5 or 6x a day. It just keeps the metabolism up.

Dr. Ben House: Sounds good.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: I’m—I’m—I train so hard that you could I mean—

Dr. Justin Marchegiani: Yeah. I get it. I get it.

Dr. Ben House: I’m not doing pull ups—

Dr. Justin Marchegiani: You’re done. You’re done after that. You’re done, man. Absolutely. So right now, we have a lot of listeners that may not be at that professional level, right? You know, frankly, they wanna be healthy, they wanna be energised, they wanna have good relationships. And then probably I can say that they probably wanna good look naked, right?

Dr. Ben House: Yeah. Yeah. That’s the point also.

Dr. Justin Marchegiani: Yeah. So what are the top 5 movement patterns those people should be doing? And maybe you wanna differentiate man and woman so in case something is different there.

Dr. Ben House: Uh— So I would say first of all, like just how people are gonna come see us for a lot of like metabolic stuff and all the—everything that we do for functional med. See somebody who’s good at movement—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Like—like you’ve been at a desk your whole life and you can’t take an exhalation. Like you probably shouldn’t be deadlifting.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: Like if you’re stuck in this state of extension. I don’t know that that’s—are you really gonna even activate your hamstrings? I have no idea, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Especially __Uh—so I think we wanna be able to use—we have to be able to use the big guns. We gotta—you know—hamstrings, quads, back—

Dr. Justin Marchegiani: Yup.

Dr. Ben House: Chest, right? And so you’re gonna—you wanna squat, you wanna deadlift, you wanna benchpress, you wanna military press, but it’s always risk vs. reward. So the risk of anytime you strapping somebody, 2 hands in a bar is higher than if you put on single limb, one arm weighted, right? Or one leg weighted.

Dr. Justin Marchegiani: Yes.

Dr. Ben House: And so for me it’s all about how do we individualized this to the person? And if you don’t individualize this, what we’ve seen is—so one of my—one of my good friends in—we used to—we have a business together in Austin, his name is Erin Davis. He’s probably—he’s like the most unknown exercise scientist. And he’s like purposely so. He’s like a hermit. And he’s a—

Dr. Justin Marchegiani: Nice.

Dr. Ben House: He’s an insane, right? And so he straps up all these gadgets to this dude. And he’s like—and – he just messes bench pessing. He’s like, “What the hell? You’re chest doesn’t even turn on.” Right? And so he can’t even—out of a barbell  bench pressing, he can’t even get the guy’s chest to turn on because of his positioning. Gives him a dumbbell, boom, he can get—he can get pec activation. So I think it’s—

Dr. Justin Marchegiani: Oh, wow.

Dr. Ben House: So I think it’s really important that you see somebody who’s good at movement evaluation so you can look at your position, right? Coz muscles are slaves to position.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: So the position—who the he—what are you gonna do? Uhm—and I think there’s DNS, PRI. There’s a lot of uh—FRC. There’s a lot of things that are looking at that now.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uhm—and there’s a lot of people that are really good at it. And so see them, pay them for their time. Uh—in Austin, there’s a guy Steve Cuddy who’s amazing.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uhmm—Erin Davis and Pad__ is obviously really good and Dave R__ has done the same as Marcus—who’s awesome as well.

Dr. Justin Marchegiani: That’s great. So what are the top 5 movements?

Dr. Ben House: You tell me. What’s gonna activate the biggest muscle groups?

Dr. Justin Marchegiani: So for me, off the bat, it’s gonna be deadlift coz that’s the only one that connects upper body and lower body but actually doing with correct form really activating the lats, locking them down. Number two would be squat. I wanna get your take on front squat or back squat, though. I would do uh—pote—I’m a big fan of unilateral single leg like deadlift movements. I like those with cables. Big Paul Chek fan with that. I would say step ups and/or lunges and then after that, I mean, If I’m doing a movement, I would wanna do something that has explosion. So I would wanna do either uhmm— snatches or uhmm- cleans or sprints.

Dr. Ben House: Yeah. I would—I would pick like maybe one of those. Haha—

Dr. Justin Marchegiani: Oh, let’s hear it.

Dr. Ben House: That’s good. That’s great.

Dr. Justin Marchegiani: I want—I want your take. Let me hear it.

Dr. Ben House: Yeah. Yeah. Uh—So you gotta—upper body pulling is like super—you gotta have—you gotta have one of those in there.

Dr. Justin Marchegiani: Yup.

Dr. Ben House: So whether—that’s probably a lot. Maybe a pull up if you can do it right.

Dr. Justin Marchegiani: Okay. So you’re talk—Alright. Got it.

Dr. Ben House: Uhm—if someone’s goal is just health, probably most people’s goal is hypertrophy.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: So in my mind, they need to get really, really really good at the fundamentals.

Dr. Justin Marchegiani: Okay.

Dr. Ben House: Variety may not be your bestfriend.

Dr. Ben House: You may need some of it just to keep you—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: –in the game. But you gotta be—I would probably use a trap bar. Uhm—safer for the general population. You can load it up.

Dr. Justin Marchegiani : Yeah.

Dr. Ben House: Uh—it’s gonna be more quad dom. Uh—

Dr. Justin Marchegiani: Yup.

Dr. Ben House: I’m—So the—From the—from the deadlift perspective.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: I think it’s great but if you’ve been a gymnast or if your hamstring length is really, really long, if someone can palm the floor, I’m gonna be very—I’m not gonna use—I’m not gonna throw a deadlift at somebody right there.

Dr. Justin Marchegiani: Okay.

Dr. Ben House: I’m probably gonna use—I’m gonna use maybe couple of Bulgarian split squats, Which is probably my favourite exercise for the general population. Where you like get to activating the hamstring uhmm—from a front squat, back squat perspective, the muscle activation is fairly similar. Uhm—I would probably lean in the general population more towards the front squat because you’re gonna have more anterior core, you’re gonna have to stabilize, right? And also, like if you can’t do it, you—you drop it.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Whereas the back you can like—you can—you can—

Dr. Justin Marchegiani: Yeah. You’re gonna overpower it, for sure.

Dr. Ben House: Yeah. You might hurt yourself. Uh—so those are my view points. Again—and I use uhm—I think speed and doing things that people love is really important so—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: You know how to Olympic lift, and you like to snatch, you like to clean obviously. I love those things. But if you don’t like doing Olympic lift, there’s a lot of—like sprinting is a great way. But in the jumping—there’s a lot of different little things that you can do to come and get that fast twitch movement coming. Uhm—

Dr. Justin Marchegiani: Are you doing any single leg stuff?

Dr. Ben House: Yeah. You can do single-leg hops, you can do, you know, whatever. You can—I do it ton. So I don’t—I do myself in all my single leg and kinda that prep toy stuff. That’s one of my cool down. So that never leaves, right? I’m doing a lot of like prehab, rehab stuff. But my meat and potatoes is my meat and potatoes. Uhm—it’s like you can’t lose sight of that. But if someone has never train in their life, their entire workout might be prehab, rehab.

Dr. Ben House: Yeah.

Dr. Justin Marchegiani: Okay. That makes sense.

Dr. Ben House: Does that make sense?

Dr. Justin Marchegiani: Yeah. Totally. Now you’re reading a lot of studies. You’re spending 4 hours a day on Pub Med.  What are the key things that you look at in the studies so that you don’t get tripped up by you know—coz sometimes the conclusion might not match what the actual study has done. Just—I know we don’t have an example here, but what are the key things people should be highlighting or looking at when they’re reviewing the study?

Dr. Ben House: That’s a—that’s a problem to question. So like UT was kinda burning to us in the PhD department really, really early.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uhm—the first thing he looks at is the chart.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: So you go straight to the figures. Uh—you look at the figures and then—and then you kinda look at the stats section. You figure out— And this is from a research perspective.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Then you look at the stats section, then you look at the subjects and then you start digging the—everything that’s going on the method section. Before you look, at the conclusion and maybe—sometimes I’ll just—I’ll buzz your abstract to see what I wanna read. I’ll definitely do that. Uh—but the problem is most people, even myself, being out of the grad school for, you know, a year and half-two years. We don’t—I don’t like looking at a ton of stat research. So like Microbiome data. It’s probably the best example here. Like our lab run a ton of microbiome data.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: We got stool samples on many people, we sent that out – yeah we send it out to another lab. Uhm—and that guy get all the analysis—all the genetic analysis on the poop.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And then that guy couldn’t even analyze the data. So had to send it to a statistician to analyze the data so that we can have—we can think about it. So think about all that. Like that is—

Dr. Justin Marchegiani: Lots of steps.

Dr. Ben House: Now you ask the general population. You’re asking the general population to look at some kind of general linearized cluster analysis. But I don’t even know what day it is, right? And so—that uh—that—like—you know—and so they have—they tend to digestible and take away. So there’s a lot of reliance on science. If you see a study, and this is kinda something that we could talk about. You see a study that’s running like 20 paired T-test, I’m immediately like, “What the hell are you doing?” Like you can’t run—it’s—you have this 95% like a .05 alpha.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: So in order for something to be statistically significant it only has to happen 5% of the time, essentially.

Dr. Justin Marchegiani: Right.

Dr. Ben House: And so if you run 20 tests, one of those is gonna poll just from a statistical standpoint. So that’s—you gotta be careful with that. So in that situation, I’m looking for a manova instead of an inova.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uh—so if you see kinda like this fishing explanation which you’ll see a lot, you just see the smorgasbord of data. Uhm—be careful with that. And so—coz it can—that’s one of my favourite things to pick apart.

Dr. Justin Marchegiani: Anything else? So let’s summarize that. So you like the manova—you look at the—the uh T-score, right? The .05 you’re looking at that as well.

Dr. Ben House: Yeah. Yeah.

Dr. Justin Marchegiani: You’re looking at—

Dr. Ben House: You go ahead.

Dr. Justin Marchegiani: You looking at the graph—you go ahead.

Dr. Ben House: Yeah. You just—so we wanna make sure that something is—something can be  statistically significant but mean to us.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: So if it is— if it’s like say, you have a .1 rise in testosterone, but it’s at the .001 level, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Okay. You have a statistically significant finding but it’s clinically meaningless. So we gotta make sure that—that their findings actually mean something.

 

Dr. Justin Marchegiani: Totally. Awesome. That’s helpful. Anything else you wanna add on that?

Dr. Ben House: Yeah. I think that Alan Aragon, the best way to learn about research is to read other people’s critiques of research. Uhm—and Alan Aragon has his research review. And it’s a steal. It’s 10 bucks and you get 8 years of monthly research review. So if you wanna get good at reviewing research, the best place is you just read it.

Dr. Justin Marchegiani: Yeah. Totally makes sense. Now you mention back earlier that you are looking at a lot of blood patterns. What are the big patterns that you’re seeing pop up? Are you looking at thyroid? Are you looking at protein digestion by some of these markers? What are you seeing in blood?

Dr. Ben House: Yeah. So the first thing—the first thing that I’m gonna look at is haemoglobin and glucose control.

Dr. Justin Marchegiani: Yup.

Dr. Ben House: Uhm—that’s not the best measure for athlete because they’re gonna dispose of red blood cells faster than general population.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: So if you see a high HbA1C in athlete, you might actually be a little bit more worried. Like maybe like 5.6, you’re like, “Uh—what’s going on with you?” uhmm—

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: And that all goes to context, too. Like are they gonna gain? Are they trying to gain weight? Then I’m not—they’re not probably not gonna get diabetic if they have a ton of muscle mass.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uh—And that’s all context dependent. And I actually like—I’m—I don’t put a lot of weight in my fasting glucose and fasting insulin.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: Uhm—you’re probably gonna see this, right? I don’t work with a lot of chronic patients. So that—that—C peptide and those measurement fasting can be really good for those kind of patients.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But when you—when you got a guy who’s 6’1, 8% body fat, that’s probably not gonna tell you much.

Dr. Justin Marchegiani: No.

Dr. Ben House: Uhm—and so I—what I really like to do is I like to use glucometer protocols.’’

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: Uh—and so I have people grab—

Dr. Justin Marchegiani: Come on right here.

Dr. Ben House: Just grab it 13x a day and see what happens.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And send me—send me a graph and send me when you eat and let’s have a—let’s have a discussion. Coz if you eat 3 rice cakes and you go to, you know, 200. That does not happen.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: You’re storing glucose in urine like we don’t want that to happen. So that’s the way we can kind of, you know, tweak carb load. The next thing uhm—obviously, you need thyroid support.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: You need thyroid hormone. It runs in every cell of the human body. So I’m gonna drop—from there, I’m probably gonna drop down to thyroid and see what’s going on there. Uhm—I mean I’ve picked up so many like—Hashimoto’s in like 14-year-old kid like one of the best pictures in Texas.

Dr. Justin Marchegiani: Wow.

Dr. Ben House: And he couldn’t recover, right? He constantly has this stupid injuries. And we grab  his lab work, his TPL is like 300.

Dr. Justin Marchegiani: Whoa!

Dr. Ben House: And we’re like—Yeah, and we’re like, “okay”  And he feels better, right? All these—we can’t—I can’t—his dad is like, “Oh, he needs to eat like Brady.” All that stuff—

Dr. Justin Marchegiani: No.

Dr. Ben House: I’m like, “No, he doesn’t.” Like—and now the kid is taking ownership of it which is amazing. He’s like—he’s like, “No, I’m not gonna eat that.” And so now, he on—he pretty much eats only autoimmune paleo. He have some rice, he does okay with rice. Uhm—and he couldn’t—he was overweighing, still crushing it like meanest curve ball uhm—this side of Mississippi. And so—but now—he’s—he’s—he looks amazing, right?

And if you play at these schools, these Texas schools, you gotta look the part. Like even if you’re—even if you’re amazing, you have to—you have to look like an animal.

Dr. Justin Marchegiani: Absolutely.

Dr. Ben House: That’s kind of unfortunate.

Dr. Justin Marchegiani: Yeah. I mean have Hashimoto’s myself and I play baseball and sports and football growing up. And I had lots of injuries coz I was trying to eat 11 servings of grains in the food pyramid, so there’s a lot of misinformation out there. And again, a lot of people are seriously inflamed. And the more inflamed they are, the more catabolic. The more catabolic, the more they can’t recover and uh—put on muscle and heal, essentially.

Dr. Ben House: Yeah. To me it’s like—it’s all about breaking cycles, right? My dad has celiac disease.

Dr. Justin Marchegiani: Wow.

Dr. Ben House: We found out—we found out when he was like 40, like 10 inches of his colon moves—

Dr. Justin Marchegiani: Oh, man.

Dr. Ben House: His gallbladder is tightening up.

Dr. Justin Marchegiani: Yikes.

Dr. Ben House: Like that’s why I got into this. I was gonna go to medical school.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And my dad got super screwed up by the conventional medical system. He was having pain killer on demand. Uh—and then I was in Colorado and I—Breaking the Viscous Cycle, I’ve read the book—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: And I was like, “Hey dad, let’s just change your diet. Three A’s set him free, he was struggling like 10 years.

Dr. Justin Marchegiani: I know. Isn’t that crazy? Dude, I know. I see it everyday. I mean—it’s—we have he most rewarding job in the world.

Dr. Ben House: Yeah, for sure.

Dr. Justin Marchegiani: Because you get someone banging his head against that conventional medical wall for 10 years plus, at some point, they started throwing it back on you. Saying it’s in your head, and they start making the Psychophol, right? And writing scripts for Zoloft and such. And then you’re just like, “ My god, this can’t be real.” You know—it’s gotta be real. So looking where you’re at, uhm—you mentioned uhm— blood markers. Anything else? You’ve talked about thyroid. Any specific cut off that you wanna talk about with TSH, T3 or antibody levels?

Dr. Ben House: Uh—Yes. So what I’m—I’m use uh—I use a software And so I’m always looking at total T3, total T4, free T3, free T4 and—so I’m always looking at what’s going on with that. Are they producing a ton of T4 but then they’re not converting any of it to T3?

Dr. Justin Marchegiani: Right.

Dr. Ben House: All the thyroid hormones are bound up. Like are they on—which is to me—like I see it constantly like if I take on a female client. I’m like, “Oh, your thyroid hormone is bind up, are you on birth control?” “Yeah.”

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: There it is, right? It upregulates thyroid body globulin.

Dr. Justin Marchegiani: Right. Uptake. Uh-hmm.

Dr. Ben House: One of the ways that we know—we know that testosterone increases lean mass and metabolism is that it dominates your thyroid binding globulin. So—

Dr. Justin Marchegiani: Totally. Yeah. Makes sense. You see that in PCOS, right?

Dr. Ben House: Yeah.

Dr. Justin Marchegiani: Yeah. Exactly. So we got the thyroid. What are you looking at for protein digestion? Are you looking at globulin, creatinine, serum protein, albumin? What are you looking at?

Dr. Ben House: Uh—so yeah I think total protein and globulins are soft markers for—I always think of them as like check engine lights. They’re not like end-all be-all.

Dr. Justin Marchegiani: Yeah. Uh-hmm.

Dr. Ben House: But if I see them low, “Oh my god, let’s keep some work add on that situation.” Uhm—and then kidney markers—In athletes, like this is like—

Dr. Justin Marchegiani: Bone creatinine.

Dr. Ben House: Oh my god, this is like—I love talking about this because that—does can actually—kidney markers are essentially useless, right, in athlete. Because blood urine nitrogen is the breakdown of protein products.

Dr. Justin Marchegiani: Right.

Dr. Ben House: So if you’re in a Ketone, high protein diet, you’ve already—you’ve knocked that up. Now creatinine is indirect measure of muscle mass. So if I have a jacked gorilla who’s in a ton of protein, he’s automatically gonna have a GFR that’s probably pretty screwed up. But his kidney function maybe fine. Uh—so the best marker there is statin C. And so if someone is super worried about their kidney function, I’ll run that coz that’s not affected by protein intake or muscle mass.

Dr. Justin Marchegiani: Statin C for the kidney?

Dr. Ben House: Uh-hmm.

Dr. Justin Marchegiani: Okay. Yeah. Yeah. And I’m not seeing patients that are at the same level as you know, being an athlete but I do try to keep them 48 hours away from strenuous workout so you don’t get those false positives.

Dr. Ben House: Yeah. I do that as well.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Uhm—but the re—it’s all individual. So they’ve done studies, it can be 10 days that you’ll see like liver enzyme’s high, bilirubin high. So you can—you can see those things. It all depends, some people get back in 48 hours and obviously we can’t tell people not to train for 10 days. Uhm—that’s not gonna work.

Dr. Justin Marchegiani: Right. Right.

Dr. Ben House: We won’t do that. But I think 48 hours and making sure that their hydration is really, really solid.

Dr. Justin Marchegiani: Yeah. And do you think muscle soreness would also be a pretty—pretty good subjective indicator? Making sure that they’re not incredibly sore or like in pain or you know, hurting from the workout?

Dr. Ben House: Yeah. I think it’s probably good from an inflammatory standpoint.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: You’re gonna—with CRP, you’re gonna see an acute rise with exercise and that is a positive in that overtime. Uhm—I—I hate muscle soreness like it’s— maybe—I don’t know if we have research to say that. It’s such a subjective indicator.

Dr. Justin Marchegiani: Yeah. Totally.

Dr. Ben House: And it’s so variable.

Dr. Justin Marchegiani: Got it. Is there anything else you wanna let the listeners know? Anything else on your health pocket that you’re kind of researching or on top of mind?

Dr. Ben House: Yeah. I think we can kinda get lost in kind of the little things, right And so—just make—I see a lot of people that are, you know, worried about something regarding their health.

Dr. Justin Marchegiani: Totally.

Dr. Ben House: And that—that’s probably not good. If you are incessantly worrying about your health, that—that’s a problem.

Dr. Justin Marchegiani: Uh-hmm.

Dr. Ben House: I saw, you know, a lot of type A people that come to functional med and so one of our jobs is like, “Hey, like, you’re not gonna die.” Like—

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: This is okay. Like—

Dr. Justin Marchegiani: It’s alright.

Dr. Ben House: You have a homocysteine of 9, you’re not gonna get killed tomorrow. There’s things that we can do.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: Let’s do all the things. So I’d say focus on the effort—not necessarily— always focus on effort. Uhm—and that’s my biggest thing.

Dr. Justin Marchegiani: Got it. And who is your ideal patient? Coz I know you made the switch from the athletic world to the functional medicine world now. You had your experience with your dad with the celiac thing. So you have some autoimmune experience. Who is your ideal patient? Someone who wanna come to see you?

Dr. Ben House: Yeah. My ideal patient is a male, any—any age range, uh—but probably a male that just wants to look good, feel good, look good naked, right?

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: That’s my prototypical client. Uhm—and then, anyone is free to email me, obviously. And like I have—I get crazy emails like, “Hey, I have a—I have a tumor in my hypothalamus. Can you help me out? And no, I can’t but uhm—let me—let me refer you out to someone who might be able to reboot your entire endocrine system.

Dr. Justin Marchegiani: Totally. So functionalmedicinecostarica.com ,right?

Dr. Ben House: Yeah. That’s the website.

Dr. Justin Marchegiani: Love it, man. Very cool. Anything else?

Dr. Ben House: Thank you for all that you do. And just uh—just putting out there information that we all have—we all have our mediums. And you do a really good job in just finding awesome people and interviewing them. And—and letting them tell story. So thank you.

Dr. Justin Marchegiani: Right. I appreciate it, Dr. Ben. I appreciate it. And the last question for you, if you’re on a dessert island, you can only choose one supplement, one herb, one nutrient, what is it?

Dr. Ben House: Uhm—

Dr. Justin Marchegiani: Haha—

Dr. Ben House: I’m gonna pick magnesium.

Dr. Justin Marchegiani: Magnesium. Okay. Alright.

Dr. Ben House: I’m probably get—If I will get a multi, I’m gonna—I mean—If I’m training on this island, uhm—maybe a protein supplement if I can’t find enough meat.

Dr. Justin Marchegiani: Yeah.

Dr. Ben House: But uh—yeah definitely—I mean most athletes are deficient in magnesium. It’s—if you give an athlete magnesium, and they’re deficient and like, they’re gonna feel a lot better. Uhm—

Dr. Justin Marchegiani: Awesome, my man. Well, thank you for that great feedback. Doctor House in the house. You can see him at functionalmedicinecostarica.com

Dr. Ben House, I appreciate you being on the show.

Dr. Ben House: Thank you, sir. Have a great day.

Dr. Justin Marchegiani: You too. Take care.


References:

functionalmedicinecostarica.com

Documentary on The Disappearing Male

Tripping Over the Truth by Travis Christofferson

Breaking the Viscious Cycle by Elaine Gottschall

 

The 5 Causes of Nutrient Deficiencies

Causes of Nutrient Deficiencies

By Dr. Justin Marchegiani

Good nutrition is what our body needs to prevent us from having issues that will compromise our health. Watch this video and increase your awareness when it comes to different causes of nutrient deficiencies.


5 Different Causes of Nutrient Deficiencies:

  1. Inflammation
  2. Conventional food
  3. Inadequate Supplements
  4. Infection
  5. Medication

Inflammation

Inflammation

There are couple of different kinds of inflammation. We have an acute inflammation, wherein you cut your finger, a scab forms or above your elbow, a bruise forms. It healed up in a few days and it’s not a big problem. 

What we’re talking about is systemic inflammation. Meaning, it’s systemic throughout the whole body based on diet, lifestyle, exercise. All of these factors.

One of the biggest things that affects inflammation is which kind of diet we eat. We’re eating a pro-inflammatory diet, high in sugar, high in inflammatory compounds like grains and sugar. Those are going to put our body in a more inflammatory state. The more inflamed we are, the more we decrease ability of our body to absorb nutrition. 

Now we have little finger-like projections called microvilli in our small intestine. Think of these finger-like projections like a vacuum cleaner. It’s job is to suck up nutrition. The more inflamed we are, systemically, think of that vacuum cleaner, each finger being a vacuum cleaner. Each one gets clogged and you see less vacuum cleaner until we have knocked – our vacuum cleaner is essentially fully clogged which does not absorb nutrition as effectively.

Conventional Foods

Conventional Foods

We’re just eating foods that are conventional. Conventional foods – meaning foods that aren’t organic. They’re not going to be as high in nutrition because the fact they are sprayed with pesticides and herbicides. Even GMO things like Roundup. These compounds with chemicals essentially devoid will make the nutrients in the soil very much devoid. Minerals are needed for the plant to essentially produce an optimal spectrum of nutrients. Studies have shown that certain soil that are devoid of manganese, certain vegetables and the fruit will actually have 50-60% less Vitamin C. If we have low mineral soils due to the chemical that our farmers are putting on it, that’s going to affect our ability to get much nutrition from that in the first place.

Supplements

Supplements to Counter Nutrient Deficiencies

Having high quality supplement is going to be really important. Even if you are actually taking high-quality organic vegetables and eating high-quality organic meat, you’re still going to have some holes there. That is why supplement is there, essentially supplementing the gaps and the holes in the diet. You never want to supplement and eat bad, either. You really want to do your best to make some big change with your diet and also add those in helping building the gap to prevent nutritional deficiencies.

CLICK HERE to know more about the supplements which prevent nutrient deficiency

Infections

Infections

Infections are very common. These are these low-grade kind of inflammatory zombies, so to speak, in your intestinals. Just sitting there and its causing this drain on your immune system, this drain in your adrenals. If we can really cut down and figure out what kind of infection to go along with (H pylori infection, or a fungal infection, or a parasite infection) and if we can diagnose where the infection is, we can create a protocol that will help remove that.

Medications

MedicationsMedications are common and are known to cause nutritional deficiencies. There are actually textbooks on nutritional deficiencies caused by medications. So did you know the most common nutritional deficiency caused by a medication is a statin? This statin medication, which control cholesterol being produced by the liver, they actually decrease your production of your nutrient called coQ10.

CoQ10 is actually really important because the hearts need coQ10 to actually beat each time. We’re having our heart issues, congestive heart failure, atrial fibrillation, blood pressure. You should really want to make sure our heart has all the nutrients it needs. Two, coQ10 is really important for muscle production. One of the most common symptom you see when you’re on a statin is rhabdomyolysis or you see infected muscle pain or extra muscle soreness. These are very, very common things. Also, in diabetics taking Metformin or Glucophage. These medications cause mixing conditions B12 anemia.

If you’re on medication, give the office a call. At least make sure you’re being supported or the potential nutritional deficiencies that could be caused by the medication you’re up. If you really want to address the underlying cause of your condition, or what medication to prescribe, let us know and we’ll do our best to help.

CLICK HERE to know if your medication is causing nutrient deficiency

Healthy Meal Tips – How to Create a Healthy Meal

Healthy Meal Tips

By Dr. Justin Marchegiani

Keeping in mind that what we eat should be nutrient-dense, toxin-free and high-quality is what this video is about. Gain beneficial information regarding the three macronutrients which are proteins, fats and carbohydrates. Know more about the different types of carbohydrates that we need depending on our activity level. Learn how to set up your own quality, nutrient-dense and toxin-free meal with the variety of foods discussed here.


Macronutrients

macronutrients

Every single meal should have a combination of three macronutrients –  proteins, fats and carbohydrates. We are just taking  fully into account that quality is really important.  A lot of people just talk about macronutrients like proteins, fats and carbs and do not emphasize the quality of nutrients that are very important. So, obviously organic, chemical-free pesticide-free, free-range, GMO-free. All these things are really important present in macronutrients.

The big thing is I’m going to emphasize macronutrients that also don’t have a lot of toxins in them. A lot of toxins are just phytates, oxalates, various fibrin compounds. Things that trip an inhibitor. Our enzyme-blocking inhibitor compounds can also affect digestion and your ability to breakdown and utilize B proteins and nutrients for food. And next is we also want to make sure that food are anti-inflammatory.

Three Prostaglandin / Eicosanoid Pathway

  1. Prostaglandin 1 (anti-inflammatory)
  2. Prostaglandin 2/ Arachidonic Acid (pro-inflammatory)
  3. Prostaglandin 3 (anti-inflammatory)

I’m going to be talking about various proteins and fats that are going to stimulate the anti-inflammatory 1 and 3 pathways vs. the refined vegetable oils, GMO vegetable oils to stimulate the prostaglandin 2 pathway.

PROTEINS AND FATS

Proteins and Fats

We’re going to have protein, fats typically come together when you eat at lunch or eating protein powders or once you’re eating rabbit protein. They have rabbit starvation up in the  in the wintery areas because the rabbits are so lean. They develop rabbit starvation of this protein hydro excess with no fats, and you actually need fatty acid to be able to help absorb proteins and amino acids so you can develop rabbit starvation without enough fat. But typically, in mother nature, you’re going to have protein, fat together. I’m a big fan of at least making half your meal, put half your plate with protein and fat.

If you are very active or if you’re a wall closer to the equator, you may be able to use more carbohydrate for fuel. So you actually see yourself in 3 quarters to 16% carbohydrates. But if you’re relatively leaner, you’re not exercising too much, and you’re living a pretty good lifestyle, typically about half protein, half fat. And that can change based on your activity levels, your kinetics, whether you have an autoimmune condition or not.

CARBOHYDRATES

Carbohydrates

We have a couple of different kinds of carbohydrates. We actually have starchy carbohydrates. This would come in the form of white potatoes, sweet potatoes, yams, tubers, bananas, etc. We also have non-starchy carbohydrate.

I’m a big fan of non-starchy varieties because it tend to be higher in nutrition. But they don’t have all the sugar that you may get with the starchy carbohydrate. This tend to be a really good place to get all the nutrients, all these anti-cancer compounds in the non-starchy variety.

Now again, if you’re more active, you may need some of the starchy carbohydrates. So this is kind of dependent upon your activity level, as well as your genetic predispositions and also you know, assuming that you are healthy. If you’re diabetic, you have metabolic syndrome, if your waist is greater than 40 inches for male or greater than 35 inches for female, you may want to think about really keeping those starchy carbohydrates down, if not out of your diet completely.

High Glycemic

This can be pineapple, this can be banana, papayas, dates, mangoes, maybe more of your tropical fruits. Now people- but, of all the more tropical environment, they may have the genetic ethnic and biochemical individuality to process those carbohydrates at a higher level. Now if you got more wintery environment, you haven’t had those type of fruits. So you maybe a little bit more sensitive to it, you may not be able to eat as much.

Low Glycemic

Low glycemic may be your berries, maybe your apples, like your green apple. Things like that, usually below above 40 glycemic index are going to be your berries or apples, maybe more of your Granny’s Smith apples and such. It kind of gives you a good idea of what your low glycemic fruit maybe.

So myself, I typically try to consume more non-starchy and more low glycemic fruit. If I’m more active, then I will do a little bit more starch, at least more of these sweet potatoes. And again, out of the starchy ones, the sweet potatoes are actually lower on glycemic index than your white potatoes.

So just kind of keep that in mind. And typically all of my carbohydrates are still gluten-free. So I typically try to consume gluten-free carbohydrates just because we’re trying to keep up with the fact that our goal’s anti-inflammatory, nutrient dense, low in toxins, and gluten-free. These are all gluten-free here.

Know more about gluten-free carbohydrates by CLICKING HERE

WHAT TO INCLUDE IN YOUR HEALTHY MEAL

Healthy Meal

So proteins, fats, carbohydrates- from there, you can create your meal.

Proteins

If you’re looking at proteins, it could be fish, it could be turkey, it could be grass-fed meat, it could be lamb, a good quality steak or beef. When we look at our fats, typically protein and fats are connected. So we’re looking at beef, and maybe a 76% grass-fed beef and maybe a dark turkey leg or chicken thigh, or the chicken breast- we’ll leave the skin on. If it is a leaner meat like a chicken breast, maybe we put a scoop of coconut oil in there; or we cut out the half to a whole avocado and put it on there. We can also have a handful of nuts or almond to get that extra fat. And again, we can obviously cook with fat, too.

Fats

Good healthy fats, maybe coconut oil or ghee. If you’re autoimmune, you may want to avoid the grass-fed butter or use something like ghee without the P casein protein in there. Also nuts, it could be good quality bacon fat and duck towel,  macadamia nut oil, avocado oil which are pretty good fats. It could be olive oil. Using olive oil as the salad dressing. That kind of gives you an idea of proteins and fats.

Carbohydrates

Our starchy carbs are going to be our sweet potato, our yams, berries, tubers,  squashes, white potato.

Non-starchy ones are going to be our spinach, its’ going to be our salad mix, our broccoli, our kale, our asparagus, our cauliflower, and spinach, etc.

Our high glycemic fruits of foods are going to be obviously, our white potatoes are going to be our high glycemic index. Obviously, sugar in general. We are keeping this list gluten-free here, just in case.

Low glycemic are going to be our berries, our passion fruit and our Granny’s Smith apples, our grapefruit, as well as our lemons and limes.


So I hope this video is really helpful. From here, you should be able to create an anti-inflammatory, nutrient-dense, low toxin meal. Start pushing your body into anti-inflammatory state, which is essentially your body building up faster than you’re breaking down.

So if you’ve hormonal issue, or digestive problem, if you’re in chronic pain, if you have fatigue, or depression or a mood issue, this is going to be the kind of diet template-wise, maybe a couple of tweaks regarding macronutrients. This is the kind of diet you want to be on health, bring yourself back out well.

For more information about myself, feel free to visit the information bar below. If you need a consultation regarding what tweaks you can make to your diet or what lab test, feel free to reach out and I will be able to help you out.

CLICK HERE and ask an expert about tweaking your diet to fit your needs


The entire contents of this website are based upon the opinions of Dr. Justin Marchegiani unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Justin and his community. Dr. Justin encourages you to make your own health care decisions based upon your research and in partnership with a qualified healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Dr. Marchegiani’s products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products.