Bridgit Danner – Hormone Balance After 40 – Podcast #138

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Dr. Justin Marchegiani and Bridgit Danner engage in a discussion about hormone issues in women at the age of 40. Learn how hormones work and understand their driving factors and effects on women. 

Gain beneficial information about hormonal balance and imbalance. Find out about the diseases one can get from an unbalanced diet and lifestyle. Be informed on ways to cope with hormonal problems as Dr. Bridgit Danner shares some tips and natural solutions based on her knowledge and expertise as a functional medicine doctor.

Bridgit Danner

In this episode, we will cover:

11:05   How Sugar Intake Affects Hormones

25:35   Relationship Between Cholesterol and Menopause

33:10   Liver Detoxification and Hormone Balancing

39:52   Supplements to Balance Hormones

46:53   Cortisol Spikes at a Time in a Day
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Dr. Justin Marchegiani: Hey there. It’s Dr. Justin Marchegiani. Today we have Bridgit Danner on the Podcast, really excited. She’s got a new summit, “Hormone Balance After 40,” coming out in the next few weeks, so we’re excited to talk about some female hormone issues and drop some serious knowledge bombs today. Bridgit, how are you doing?

Bridgit Banner: Great. Thanks for having me on Justin.

Dr. Justin Marchegiani: Great. Well, I know we kind of were doing a little recording earlier and got cut off, but let’s continue with that question. So you did a summit. You interviewed lots of experts on female hormone issues. What were those top three nuggets that you gleaned from the summit. Now, obviously there will be a “Summaries” we want everyone to tune in. We’ll put links below so people can access this great info too. But what are those couple of tidbit nuggets?

Bridgit Banner: Yes, and I say number one is, you know, menopauses. Inevitable. But uh– your symptom level is changeable. So, you know, it’s not like oh well I just have to have Hot Flashes, or gain 20 pounds, or…

Dr. Justin Marchegiani: Totally.

Bridgit Banner: …get an Ambien like, no. So- but just like you do on your practice, it’s often getting to the root of like, “how did you get into perimenopause”, “in an imbalance state, are you exposed to toxins”, “do you have a gut infection”, “are your adrenals running down.” So, you know it can be a- a tough time for women, but also a great time to like okay– like maybe I’ve been ignoring my health a bit as I’ve crushed my 30’s and like raised kids. And, you know, now it’s like I’m starting to feel something’s catching up to me. You know, I want to eat well. I want my hormones to be as balanced as they can. And there is, there is a lot to be offered. And there’s a lot to learn. So that’s, that’s one thing. Another thing we talked about a minute ago was uhmm– the good fats and oils. Wow, just– there’s like, one great tip I have for women at this age group is adding in some beneficial oils that help your hormone production, help your prostaglandin production, uhhmm–, things like borage oil and hemp oil. These, these things, they’re not food we eat, really.

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: You know. We talked about Paleo. Yeah great. There’s some great ingredients there but, like, no one eats, like, borage flowers.

Dr. Justin Marchegiani: Borage oil or black currant seed oil too.

Bridgit Banner: No. No one has those things.

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: So those can be some really beneficial supplement. Uhhmm– another one comes to mind is sleeping. You know, working on improving sleep quality at this age because it can really be disrupted as your hormones change. But yeah, it’s so important because we’re healing. And yeah I wrote an article like sleep is our fountain of youth because we have all these growth hormones that happens when we sleep. So it’s so important to get good night sleep. There’s lots of things we covered. One talk I really liked was on metabolism, which I think is like, women are just like, “Oh well, I’m screwed after 40, you know, my metabolism.” But that’s not really true though. And that can be, that can be hacked. Uhhmm– it’s just mentioning Dr. Rina Marie ____?Liscosov?____...

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: … on awesome talks about blood sugar and how balancing blood sugar is, is incredibly powerful as we age to, you know, stay energetic. So, yeah. Lots of, lots of good options. There is hope.

Dr. Justin Marchegiani: Very cool. And you mentioned that first one where you’re talking about prostaglandins or the eicosanoids, which are the same thing. And we have kind of our, our One, Two, and Three pathway. The Two is really, like, the inflammatory, like the pro, like, the refined vegetable oil tend to go that pathway a lot, like, the refined meat tends to go down that pathway. Then we have the One and the Three, right which you mentioned. And the Three is like the big one that we hit with some of those Omega-6 fats but the healthy kind of Gamma-lenoleic fats – the black currant, the borage oil, right? Is that correct? Is that a good summary?

Bridgit Banner: Yeah. I kind of remember that I’ve looked up at the three pathways, and now I can’t remember which number is which. So you see, but yeah, basically there gonna be balancing inflammation, anti-inflammatory, uhh – building hormones. Just all the good stuff. You know, you need all of them.

Dr. Justin Marchegiani: Totally.

Bridgit Banner: The body needs the total balancing. Heck, some inflammation is good. Some increase in blood pressure is good. But then you need something to balance in like…

Dr. Justin Marchegiani: Totally.

Bridgit Banner: …being able to get the blood pressure back down. So yeah, those, those are really – and fish oil too. You know, fish oil is in as much like in vogue as, you know, when everyone start to take you to, you know, ten years ago or whatever.

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: But it’s still valuable, and an– as  also anti-inflammatory…

Dr. Justin Marchegiani: Totally.

Bridgit Banner: …sparks these pathways too.

Dr. Justin Marchegiani: Yeah, I think the fish oil really helps that prostaglandin in Two pathway and kind of dampen it. And then we have the One and the Three which on those paths, and I see Gamma-lenoleic fat like you mentioned. Then it also helped with hormonal acne too. So if you’re female and you have done a lot of good diet changes but you’re still having some skin stopple. Number one always cross off the gut too, right. That’s the really important thing. But if the guts addressed, I see the black currant or the borage oil – those types of oils really help the skin health too.

Bridgit Banner: And the Zinc? Do you guys use Zinc in your practice?

Dr. Justin Marchegiani: Yeah. Oh, Yeah.

Bridgit Banner: Yeah, that’s– I’m learning more about Zinc, and it’s good for skin health, good for helping you make progesterone. Uh–

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: …and it’s in meat and stuff, you know, talking about a Paleo diet but you know, it’s all– we  still could be not getting enough, or not digesting enough, so  uhhmm– you know, how much it take. You know, one of my friends is careful about metals. She’s like don’t take too much Zinc. But, you know, I think, if you’re going through some of these hormonal changes, you could do more, like 30 milligrams Zinc. Uhhmm– you know, really up those fatty acids, and, you know, just see how you respond.

Dr. Justin Marchegiani: Absolutely. I think, too, if you’re low in Zinc, you really take a peek at the hydrochloric acid levels. Make sure you’re digesting those healthy meats, ‘cause meats are gonna be the big source. Seafood, meats, I think pumpkin seeds as well are really big in Zinc, as well.

Bridgit Banner: Yeah. Linolate in seeds. Ahuh.

Dr. Justin Marchegiani: Yeah. And a couple objective ways to even tell how you’re doing with Zinc is, number one, look at your blood test. Look at the alkaline phosphatase marker. If you’re 50 or below, there could be a sign of Zinc deficiency, and then number two is a Zinc Tally Test. I think it’s a Zinc Chloride. I think It’s a Zinc Chloride or salt – one of  the two. Take a shot of that, and if it taste metallic-y that’s the sign that you probably are Zinc-sufficient. If it taste more liquid or neutral, it’s a sign of your being Zinc-deficient. The better it taste means the more you need it. The more metallic-y, the more you kind of being repulsed by it, meaning the less – you say, the more replete you are of it.

Bridgit Banner: Yeah. It’s one of the funniest test to get in the clinic…

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: … ‘cause like, you know, like, “What am I doing. What am I supposed to be experiencing?” And I’ve also found in my practice that it’s often is best to start in the liquid Zinc to like – once you start to absorb some, then you tend to– let you switch to a pill. I’m not really sure what it is. Is it a digestion issue? I just feel it often works better to start from like a couple of bottles of the liquid. You’re not really getting a high dose, but it seems to like absorb better.

Dr. Justin Marchegiani: Better. Yeah.

Bridgit Banner: And then you can take Zinc pill.

Dr. Justin Marchegiani: I totally agree. I think the only thing is to know with Zinc if you’re gonna go really high just make sure there’s a tiny Copper in there just so you don’t throw the Copper too much. You know, ‘cause Zinc and Copper are on the seesaws. So if you go really high in Zinc, they can rob the Copper down. But there’s a lot of people that are worried of Copper toxicity anyway, so if you…

Bridgit Banner: Yeah.

Dr. Justin Marchegiani: …are gonna go above a hundred milligram or so, add a tiny bit of Copper in there.

Bridgit Banner: Yeah. Most of us, are– a hundred milligram, yeah, is a lot. And most of us are getting sources of Copper but not enough of Zinc.

Dr. Justin Marchegiani: I hundred percent agree. So that was tip number one with the really good Omega-6 fatty acids – the healthy Omega-6, not the refined fish oils. What’s number two?

Bridgit Banner: Uh– tip from the whole summit? Hmmmn–.

Dr. Justin Marchegiani: Just what resonate with you the most? ‘Cause you’re also a clinician. A clinician looks at things a lot differently. You know, you’re looking at things of, “hey what can I do to actually change a clinical outcome of my patients.”

Bridgit Banner: Well, I’ll tell you something we beat up a lot, up on a lot in the summit well– which is wine. You know it’s almost like become a caricature of a middle-aged woman with a glass of wine. You know, wine with the friends, with to come down, and I think it’s, perhaps it’s like, it starts with like a self-medication. It starts like from a busy day, and like it helps me sleep, and then it starts to be real consistent. And, you know, some people listening to your show might be having some couple glasses of wine every night, but they still may be having some more than they need to be. Because they don’t really need it.

Dr. Justin Marchegiani: Totally.

Bridgit Banner: So I think, you know, it’s a change we people like don’t wanna make at first but if you say like I, I would say, you know, don’t feel like you have to do it forever. You know, give me a month. Give me a month, and say I’ll do this for a month, and then just see what happens in your body. And, you know, see if you lose weights, see if you’re thinking clear, see if you have more energy in the morning. So yeah I think that those things in midlife that women tend to be like turning towards, that we can turn away from, and have – you know. Those are coping mechanisms, you know. Coping even for a social situations. Like when I’m nervous, I kind’a have that strength, you know. It’s just coping but you know midlife is about expanding, and like becoming more and better, and not just coping. And you know, let’s tune in and like give and tell how to go to bed sooner. You know, all those basics first. Swing then to some more specifics. But you gotta do the basics first, right? You can’t be like. “Oh no, I can’t be this way. I can’t. I’m anxious.” You gotta take that one out. Just try to take out little sweet things, all that blood sugar, you know roller coaster. It’s depleting you of nutrients that you need to make hormones. It’s just making you feel off. And with midlife, and we talk about what the hormones are doing in midlife. There’s just that already a propensity, if we’re not careful, to go a little off and feel a little off. So just wanna create like steadiness in our habits and bodies so that we can weather those changes easier.

Dr. Justin Marchegiani: Totally. That makes a lot of sense. In Dr. Diana Schwarzbein’s books, she did a book, The Schwarzbein’s Principle, about ten years ago. She’s a – an endocrinologist at the Sta. Barbara, USC Grad, and she talks about women turning towards wine because they’re a natural polyphenols that really help modulate estrogen levels. So as you go into menopause, those ovaries aren’t producing as much hormones, and the adrenals are being relied upon more, right? So the more you swing the blood sugar, the more blood the adrenals get whipped. Anyway, it’s kind of modulating some of those estrogen receptor sites.

Bridgit Banner: Huh– I hadn’t heard about that.

Dr. Justin Marchegiani: I heard people going into the alcohol. 

Bridgit Banner: I hadn’t heard about that. But then there’s also like modulate serotonin which makes us feel good at the moment. You know…

Dr. Justin Marchegiani: Well alcohol’s a sugar, right? It’ll break down the sugar, and sugar will boost up serotonin, dopamine as well. So, I think there’s a lot of different things that are happening there for sure.

Bridgit Banner: Yeah.

Dr. Justin Marchegiani: Cool. So that’s number two. I think you alluded to with the sugar as well, because when you take sugar, right, you get this hormonal adrenal roller coaster ride – insulin on the high, Cortisol on the low. Meaning when your blood sugar goes up, pancreas produces insulin to push it back down, which then drives more lipogenesis fat creation. But then when the bottom’s __?zow?___, the adrenals have to pick it back up. Adrenaline and Cortisol which then pull from some of your sex hormones. Can you talk more about blood sugar roller coaster with hormones?

Bridgit Banner: Yeah. So, one thing is like for insulin resistance, we cannot, hormone receptors can get blocked up. Uhhmm– so that’s one thing. It definitely can hurt your gut environment, bacterial imbalance, and you need your gut health to clear used estrogens. So even though hormones are coming down, some of the estrogen is often dominant. Progesterone’s falling faster because not every month we ovulate, it’s not very strong. So we need our gut healthy to clear estrogen. I was just doing some research recently and even just like one drink a day can give you SIBO. Uhhmm– yeah, like, there’s, you can’t feed that stuff. You really need to– I get heat up a lot in the summit. And that healthy gut – I’ve kind’a had clients too. You know we just took on and agreed with clients on our coaching program. Man, the stuff we find in our guts are all sorts of things.

Dr. Justin Marchegiani: Totally.

Bridgit Banner: So, it could be hard to make that connection between the gut and hormones, but it’s going on. It’s happening. So, if you can nourish that gut, and not feed it sugars, you know that’s one way to clear. Uh– what else? I mean, I think that most of sugary foods yeah– are devoid of nutrients, and they’re hard on your pancreas, and in your, in your insulin. But they are also hard on your liver, you know, to be processing and dealing with that. And you need your liver healthy to be, you know, doing its job of clearing homrmones and all that stuff, so yeah. Avoiding toxins, when there’s your food being toxic, your body cream, or your perfume, or your, you know carby cleaner. You know, just…

Dr. Justin Marchegiani: Totally.

Bridgit Banner: …really what, cutting down on all that stuff. We kind’a segued on the topic. But that came out a lot too, just like, maybe it’s time that– say, maybe if you think that well this stuff never bothered me before, but now if you’re having hormonal symptoms, it’s time to reassess.

Dr. Justin Marchegiani: That makes a lot of sense. So hormones are really affected by a lot of these toxins, ‘cause a lot of these toxins are essentially Xenoestrogens, right? ‘Xeno’ means ‘far’ and ‘estrogen’ is an ‘estrogen’ hormone. So if we’re getting impacted by a Xenoestrogen in the environment through pesticides, through chemicals, cleaning products, that can really affect our hormones, can’t it?

Bridgit Banner: Yeah. Very much so, and you know, all stored fat tissue can make extra estrogen too. Or we, you know we make fat tissue as a place to store toxins that our liver can’t handle processing because it’s, you know, so busy handling everything else. So from the connections we did, the toxins and the fat tissue and uhhmm– you know women, say, really our concern about gaining weight at this age as well. So yeah, cleaning up your habits. I mean, nowadays, there’s so many options, and they weren’t all nasty. But there’s not a research in this uhhmm– like clean, you know, clean hands soap without fragrance, then you know, one I mentioned carpet cleaner like. It’s funny sometimes you, where you forgot to look like where you forget to look like. At our, our old house, we had a carpet cleaner, and I just buy like a standard mix that you stick in there. And I realize, “Oh my gosh. What am I doing, like, this is full of chemicals.” I don’t know where in the world will I ever go to get like a natural carpet cleaner soap. And it’s, it was like one mile away – my natural grocery store. So sometimes it’s like you just forget to check certain things, but start checking. You start looking at your labels. Uhhmm– I have this, you know, I’m really hitting homes to eat organic as much as possible. And those little cheat treats, and treaks– excuse me, treats and cheese we do, those are often why we’re getting exposed to the most toxins. Like you know, if you have a little cheat and have something like a cookie, you know that, that we may have been sprayed with glyphosate, and that’s like very toxic to your gut that we talked about. It’s like an anabolic for your gut. So, I, you know, it sounds like a lot of work to be like, “Oh I have to be so clean and pure.” This sounds so horrible, but you know, just do it like it an experiment, and also know like you’re worth it. It’s not like, like, “I have to be healthy, like it’s the worst thing ever.” It’s like you can very much be happy enjoying a healthy lifestyle as you and I do. ‘Cause you have more mental power. You know, it’s like, you’re more comfortable on honestly with yourself. You’re getting a good night sleep when your moods are more balanced. You just like, life can like, be anything that you want when you’re healthy. But when you’re scoping, and having a cookie, and a coffee and whatnot, then you’re standing by. It’s gonna catch up to you too. We have one of our ____ to talked about disease, like cancer. You know, sadly, those are around the corner. You know in our 40’s that could happen. It’s gonna happen sooner but I think like when I was in my 30’s those just sounds like concepts, so far away, but, they’re coming for you. So, midlife is a great time to get better habits ‘cause no one wants to be, you know, in the doctor’s office talking about a heart disease, or could have been cancer. You know what one’s at.

Dr. Justin Marchegiani: Yeah. I mean when you’re dealing with lots of, for me in the patients’ sects. I’m interacting with lots of patients every week. We always talk about getting people to a baseline level of health, because, once people get there, the little bit of cheating that they do at the other side of the fence may throw them out of that performance on for days. The reward you get for here just is not worth the momentary, few minutes, maybe an hour of pleasure, right? So number two is figure out what that thing you want over here – let’s just say it’s alcohol. There’s different versions of alcohol. Not all alcohol are the same, right? I think it’s Dry Crepe Wines, they got a really good wine that’s gonna be low on microtoxin, low on all of the crap and the excipients and also low on the sugar. So if you want wine, they’re healthy versions of wine, healthy versions of alcohol, healthy versions of treats that will give you that mull feel, that pleasure, but not take you out of that performance zone for very long.

Bridgit Banner: Yeah yes, I know. I tried those wines, and they gave me a headache in like three sips. It doesn’t work for me. And it might just be the sugars. I know they say it’s zero sugar, I think that’s what they say with the Dry Crepe Wines, but that wasn’t my experience. So, I…

Dr. Justin Marchegiani: And for me too, I’m on the same place. I normally get headaches. I typically don’t do wine. I do a sparkling champagne, or I do hard alcohol, Tito’s vodka with kombucha, ginger kombucha. Then I make my own little Moscow mule.  Either that. So, those are my two favorites. So I agree, not a big wine person outside of the Sparkle.

Bridgit Banner: Yeah, yeah, there’s different options. I mean, I recently got my Galitoxin and I have some Candida there. And you know, I don’t have a a word but sometimes, the way I react to sugar and alcohol is a bust since the Candida. Loving it up as  soon as it comes in my mouth. So, kind’a listen to your body too. Uhh– yeah. Don’t just listen to me  and Dr. Justin. Just try stuff, you know, try giving up wine for and if, you know, try getting it back in and see, you know, what your limit is. Like what is – you know, not that I never ever had a drink, but it’s pretty rare, because I just don’t want to hinder the progressions so just a month. But then yeah, everybody’s gonna find their different thing, but I think to clean up and say it’s temporary, it’s something I’m doing for my health to experiment, then you get to be the owner of how much you put it back.

Dr. Justin Marchegiani: Absolutely, men. Tip number two is that don’t drink alcohol on an empty stomach, ‘cause that will, a little bit of fat in there will slow down that absorption so it won’t spike your blood sugar, hit your liver as hard. And then number two, activated charcoal is phenomenal, the kind of buff around those toxic bird too.

Bridgit Banner: I don’t know, like after an evening? Or..

Dr. Justin Marchegiani: I typically take it along with it. And then a …

Bridgit Banner: Uhh–

Dr. Justin Marchegiani: … a lot of time I’ll take my line, I use a liver supreme which is like milk thistle and some extra B Vitamins. You know so you get some herbs to tonify the liver a bit. And then some extra B vitamins which, you know, your body will burn out to actually help detoxify the alcohol, as well. A lot of alcoholics are deficient in B1.

Bridgit Banner: Hhhn– interesting. I’ll pay that man that say I use charcoal or clay like a fat instantly when I feel bloated. I’ve been telling that all to my clients ‘cause it’s like yeah, we wanna avoid those things that make us feel bloated. But sometimes to we accidentally have them. And then, urrh– so,  those two things really helped me to take in the evening if I’m feeling.

Dr. Justin Marchegiani:  Yeah. Even conventional medicine, I mean, I went to an ER, college roommate, many years back, ___ him on alcohol and at the ER. I mean they had him drinking the whole cup of activated charcoal in liquid form, in the ER.

Bridgit Banner: Oh my God.

Dr. Justin Marchegiani: So even in the ER, all that stuff.

Bridgit Banner: Interesting.

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: Interesting.

Dr. Justin Marchegiani: Crazy, yeah. Back to the female hormone stuff. Tip number three.

Bridgit Banner: Hmmmm.

Dr. Justin Marchegiani: By the way, we got some questions lined up, so once we get through with the…

Bridgit Banner: Yeah. I like it.

Dr. Justin Marchegiani: …go to a rapid, rapid answer. Kind of  a Q and A.

Bridgit Banner: Okay. Let’s see. Some other things that came up on the summit, say are like, ‘spacing out your eating’ came up. Having a longer time between dinner and breakfast. You know, not snacking, kind of for blood sugar, and also for gut. There’s a certain bacteria, I can’t remember what it’s called. It needs long and regular periods. We built it soft, so having that space with a gut. What else did we talk about? Oh we talked a little bit about Keto and you know, having that high fat diet, not being afraid of fats. The only interesting that came up on that talk was fiber? Uhhmm– and that it can, it’s irritating, so, you know, thinking like you need a ton of salads and vegetables, or grains, or whatever. It’s irritating, you know. But you can eat some rich foods like liver, that actually, oh, oh my God. For some people that I know. But that, that came out of my speaker thing. I’m not always the greatest to remember my tips, like my, like from my – you know, like from my– let  me try to see some of my speakers…

Dr. Justin Marchegiani: Cool.

Bridgit Banner: … to see the fun things we talked about.

Dr. Justin Marchegiani: Yes. So while you’re doing that, to– yeah, yeah. Let’s head up to some questions. So off the bat, Diana wants to know, do grains, of course, could grain-free, of course – Do grains, I think she’s referring to Gluten-free, do grains, like corn and rice, increase bad estrogens? Why do some people do so well on grains, I don’t?

Bridgit Banner: Hmmmm– That’s a great question. So I think we could say that’s possible that some grains could push that, and you know you should try it on those stuff soon.

Dr. Justin Marchegiani: Yeah. Yeah. I would say, I would say off the bat, I would say off the bat, there’s a higher level of Gluten-sensitivity genetically with yourself Diana. That’s gonna create more inflammation, a more leaky gut. That’s number one. The more inflammation that’s going on there that’s gonna take your hormones out of balance because with the more inflamed you are, Cortisol’s gonna increase, Insulin maybe out of balance, that may skew your progesterone to estrogen ratio, ‘cause you’ll pull progesterone downstream to anti-inflammatory Cortisol so that can create more estrogen dominance. Also, a lot of grains are gonna be contaminated with microtoxins and can increase LPS in the gut. And the more lipopolysaccharide that’s there as well that can potentially increase beta-glucuronidase, which is an enzyme that deconjugates metabolized estrogen and puts it back in the circulation. So the more inflammatory foods, the more foods that feed this biosis, where bad bacteria increases beta-glucuronidase which can unconjugate–deconjugate. So conjugation is nothing more than a hormone with a straightjacket around it that’s typically a protein. And that beta-glucuronidase opens it up and allows it back in the circulation which can affect your hormones so for sure.

Bridgit Banner: Yeah. That’s probably a lot more detailed than what I’d say. I would say, you did a good– you potentially irritate your gut and create some inflammation. I even wonder if some of them could like we talked about those prostaglandin pathways earlier. I wonder if some of them could push some of those more inflammatory pathways. And then I think like with stress, chronic stress, you know, your gut lining can be thinner, and not as robust, and then things are more irritating too. And then the quantities that’s really easy to overeat – grains, uhhmm– and then carbs, and then that sugar, and like, you know, the fat tissue produces more estrogen, the inflammation is blocking the receptors.

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: I think that for women, life is really finding ratio in their diets. Like, what is like, enough carbs and oils, if you know, what is like a serving size, or, you know, how many drinks is like, you know, that pushes me over, well kind of bloated. You know, it might not clear in my head anymore. So I think finding that ratio is really important. And still while women are having a protein, and a protein in the morning, you start– you brought this in your talk. Uhhmm– yeah, just getting like those whole animal, like cooking the whole chicken, getting a lot, like robust, you know, variety of fats. Uhhmm– anything is okay to have some like we talked about the nuts, seeds oils to, to do some seeds cycling. Uhh– we have like, a blog people can find to do some seed cycling challenge. People really went  with that. Probably the fiber, probably the oils on those nuts and seeds can be helpful.

Dr. Justin Marchegiani: Absolutely. Totally. Next stop here is there relationship, is there a relationship with cholesterol, high cholesterol and menopause?

Bridgit Banner: Yeah? So we, I kind’a heard two things, I would say two things. One is that we need cholesterol to make hormones, so sometimes it’s rising up like naturally to produce more hormones in this time. Uhhmm– but then our keynote speaker would say, you know, if you’re not eating, consuming enough cholesterol, your body will be forced to make more cholesterol. So we wanna to kind of avoid that by giving our body that cholesterols. Uhhmm – say the question again. Was it the correlation…

Dr. Justin Marchegiani: Yeah, so there’s a connection – the relationship between menopause occurring and higher cholesterol.

Bridgit Banner: I think there is an occurrence with it. But I think it’s, if you feel your cholesterol is out of range and those speeches are like debatable. But, you know, our speaker on Heart Health said, you know, that the quickest way to heart disease is through sugar. So it’s more like, body’s getting inflamed from the sugar, and then cholesterol is kind of increasing to repair it. So, I think to some extent, cholesterol could go up at this age naturally? But if it’s like sky high and your diet is very poor, full of sugars, it could be something to look at.

Dr. Justin Marchegiani: Yeah. I agree. I mean if you, if your diet isn’t quite in check in insulin resistance going on, that will get worse over time, and insulin does drive that hemometagluteracoreboductase enzyme that stimulates cholesterol synthesis. We can’t forget that majority of cholesterols may be by your liver. Typically, insulin sort of drive it. Poor diet doesn’t have insulin to check. That’s one vector. A second vector that could be a subclinical thyroid issue, and low thyroid function will cost cholesterol…

Bridgit Banner: That’s true.

Dr. Justin Marchegiani: …to go up.

Bridgit Banner: It’s a good point. Yeah. This is uhhmm – I would. The most common time to be diagnosed is menopausal. But second to that is perimenopausal, post-partum, uhh– I think puberty is in there. I don’t, I don’t work for that age group as much but, yeah all, every time the hormones’ changing, the estrogen can be dominant, think about after you have a PB, estrogen is very high ‘cause you’re not cycling. It’s not as high as, you know, the other times, but there’s an imbalance. There’s other things we could talk about too, but uhhmm– when the estrogen is like affecting, estrogen being high and relative to progesterone is affecting your immune system, and that could be autoimmune thyroid or that could be just an estrogen dominant thyroid condition. So that was a great point Justin.

Dr. Justin Marchegiani: Totally. I think uhh– the last piece to that puzzle is, “Does it even matter if you’re cholesterol’s high?” So, my criteria is, number one, if you’re cholesterol’s over 300, maybe we got to take a look at it. Number two is, “Do we have elevations in inflammatory markers, CRP, homocysteine, fiber antigen?” Okay. If those are high, maybe we got to take a look at it. Number three is how’s your– HTL, the total cholesterol ratio? “Is it greater than five?” If it’s greater than five, maybe we got to look at it. And then the last but not the least, is “How’d you rate the HTL ratio?” If it’s two or below, then it’s probably okay. So it’s not, cholesterol has never cut a dry number. You got to look at, I see a lot of people high in cholesterol, also at kickass HTL. So then their HTL, the total cholesterol ratio is really rock solid.

Bridgit Banner: Yeah. Yeah. Oh I hope that helps the…

Dr. Justin Marchegiani: Yeah, next is uhm – 47-year old Strakito, four years overtrained, undernourished and 40 pounds overweight. She is yeast-overgrowth, thyroid are low, all sex hormones are low, blood sugar is rising, what should she address first? Oh, she wants to address the gut first, your thoughts? This is our practitioner MP, the practitioner that wants to address the gut first.

Bridgit Banner: She’s asking if that’s the best choice, or…

Dr. Justin Marchegiani: Yes, that’s the best.

Bridgit Banner: …what kind of thing. 

Dr. Justin Marchegiani: I have my opinion but I want you to go first.

Bridgit Banner: Yeah. You know, we talked about this someone on the summit. And a few people said, we’ll see what you think Justin? I can’t remember what you said, so.

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: Some people say they work on the hormones exist to give a little relief and a little more energy. Uhh– and then they start doing some of the painful works. So just first the gut and the liver detox, then where some symptoms are gonna come up. Uhh – does it have to be that, I think what we do in our practice. I mean we’re, we’re a little bit all mixed together.

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: Uhhm – but, you know, I wanna say you wanna go after the gut in a really intense way ‘til your body is enough, strong enough like to handle it. So those detox pathways are clear. Sometimes you start with some gentle detox, and get the foundations going. Uhhmm – like I, I mentioned briefly like saying you know if I said this in the first time we’re in maybe. So, anyway  this time last year, I was having a lot of trouble with spotting, and I was also  exposed to toxic molds. I was like, I don’t really know if I’ll get my hormones right ‘til I get the molds right. I have gotten better with the mold, but I feel that you still can’t actually caught pass some of those things and address the hormones with like what I mentioned before, like the hemp oil, and the flax oil, and the fish oil. We knew, so yeah. I think you can kind of massage some of them, sometimes. ‘Cause clearing the gut takes a while. So we get some loving in there. What are your thoughts?

Dr. Justin Marchegiani: Yeah, so. When I hear that though, when I hear addressing the gut, there’s kind of a, a double lifestyle. So when I address the gut, there’s six R’s that we go through. Number one is removing the bad foods, right? That’s totally okay. We can check that one. And to yeah, two, replacing enzymes and acids better. That’s number two. Check. Yes, we can do that. Number three is replacing, or I should say repairing the gut lining. Nutrients that help with the gut lining repair and helping you deal with the inflammation in the gut, and helping you repair the adrenals, the thyroid, and some hormonal issues first. So those are the first three R’s – remove, replace, repair. Okay? So that we can do those first. Now I think when people talk about addressing gut, they tend to the fourth R, which is removing the infection of this biosis. Whatever the critters are. So I always wait, at least one month or two for that. If detox isn’t good, and hormones aren’t good, and blood sugar and immunes not good, that can really create a lot more stress that your body may not have the ability to deal with. You only have one or two months with the patient for them to start seeing something. And if they start moving backwards for one or two months, you’re gonna lose them. You’re not gonna be able to help the clinician. That’s just my personal take based on

Bridgit Banner: Yeah. And I like, this is all individual to every person, and yeah. You have to kind of start most obvious things, and I don’t know who the name of this– you know, just resting. You know, just resting your body and have some great talks and like mindset and emotional health. Just uhhmm – all are part of health too. You know, you overdid it and you’re reassessing like the direction of your health, the direction of your life. Like, ijust resting, just reading books like lying on the sun, going a vacation. These things are very healing as well. So uhhmm – yeah.

Dr. Justin Marchegiani: Totally.

Bridgit Banner: Just remember to keep that to your protocols.

Dr. Justin Marchegiani: And that parasympathetic nervous system going, I think, that has to be part of any functional medicine programmed at the foundational level is to sleep, the good healthy habits, the time to relax, so yeah. That’s a really good point and we don’t want to overlook that.

Bridgit Banner: Huh.

Dr. Justin Marchegiani: Can detoxifying the liver bring your hormone balance back?

Bridgit Banner: That’s an easy one. And do a lot for– yes. Yeah.  Yeah. Yeah.

Dr. Justin Marchegiani: I agree. I think, I think as long as your hormones are decent, like you have good institution in the gland, I think that may be enough. But if there’s a lot of dysfunction in the adrenals of the thyroid, that will help with the support of the other side as well. So I think, it totally can for sure though.

Bridgit Banner: Yeah, yes. Some part of the system that a few people mentioned on the summit, and yeah. It’s not the only piece. Nothing ever is. Just one piece. Yeah but it’s actually like what you said just removing all the toxins is important too. Like before you go into taking in the herbs, doing a coffee in the morning. Just make sure you got them out of your diet and out of your home, out of your water supply to just reduce that part.

Dr. Justin Marchegiani: Yeah. I think, you already – we don’t, our body will detoxify better just by not putting toxins in.  When we think of detoxifying, we’re giving something to help detoxify. But we can also just think about it. let’s just not add stuff as well. And then you mentioned earlier with the fatty liver, that the one of the major stressors on your liver is excess carbohydrates and insulin, because that will cause a fatty liver, which will slow down the filtration too.

Bridgit Banner: Yeah. Which is even gross to think about the cause …

Dr. Justin Marchegiani: Yeah. I know.

Bridgit Banner: … of your liver blocking, if everything.

Dr. Justin Marchegiani: I know. Absolutely. Next, estrogen dominant is related to histamine. HIT is related to methylase, to histamine as well. After addressing diet in gut’s health, bateria, parasites and yeast. We still have ED plus HIT. So, well ED means Estrogen Dominance, HIT means Histamine Intolerance. Then what can we do besides working on methylation?

Bridgit Banner: I’m trying to make sure I got all of that.

Dr. Justin Marchegiani:  It’s a little confusing with the abbreviation, but I think what they’re saying is, “Hey. I have Estrogen Dominance and I have a Histamine issue. I’ve already worked on the gut. What else can I do besides pushing my detox methylation pathways?” That’s my translation.

Bridgit Banner: Hmmm– I think you can think about hormone production. So I think you can think about what we talked about before – the fats and oils, to get. Depending on your age like, I would do more like Vitex, for like a little younger, early 40’s, but anytime in the 40’s, 50’s, doing like Maca estrogenic herbs.

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: If you can pull everything up, you know, pull the progesterone up, it will help balance that the estrogen. So, uhhmm – I think that’s an important piece that sometimes gets missed ‘cause our American, like, culture is always thinking about clearing and detoxing. But I don’t know if this person’s, have their hormones tests. But most of these are also depleted, at this age. So just like pulling hormone production up, you could see that estrogen become balanced.

Dr. Justin Marchegiani: Yep. I totally agree with you. One thing I’ll say, I think you already said it all. Potentially, adding some progesterone, maybe even some pregnenolone, DHEA. But looking at the adrenals too is an important piece.

Bridgit Banner: Yeah. You can introduce some things like macon, borage oil. Super easy on your own. Yeah but with a practitioner, you could do some simple progesterone. Uhhmm– also I get some testing for that kind of– I do well on progesterone; I don’t do so well on DHEA, pregnenolone. For my experience, everybody’s kind of different.

Dr. Justin Marchegiani:  And that, I see that too with people that kind of more backed up liver pathways too.

Bridgit Banner: Oh yeah.

Dr. Justin Marchegiani:  And maybe the mold. Look, ‘cause you mentioned your mold experience. Maybe that was the driving factor with that.

Bridgit Banner: Yeah. Back when I tried those, I was living with mold but didn’t know. So, it’s kind of, kind of flavored my whole history like, “Oh.” So, it’s interesting. And I think, you know, we haven’t talked about that. You know, there can be these hidden things. You talked about parasites…

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: But you know, I have to learn a lot about mold, and Epstein-Barr Virus, and uhh– all these things I was posting I didn’t know that. Those things really flare up with the changing hormones, not getting a good night sleep. And we talk a little bit about how that high estrogen can affect the immune system, in not a favorable way. And then, just with aging, the immune system can be deteriorating in a sense. So uhhmm – so, yeah, a lot, things can come up. You know if you feel like you’ve tried everything and you’re still sick, my personal lesson is, like, there’s probably something else going on to look for.

Dr. Justin Marchegiani: Totally. That makes sense. What do you think about supplementing with DIM Postmenopause?

Bridgit Banner: I mean I think it could be done. I guess it could clear some bad estrogen sort of thing. Is that what the person’s thinking?

Dr. Justin Marchegiani: Yeah. I mean. I’m kind of little perplexed as well. Maybe the detox pathways are running and they kind of support delivering such. But most people will have lower estrogens, especially if they’re, you know, not adding in a whole bunch of, you know, estrogen as well. So, definitely makes more sense with the cycle of female, right?

Bridgit Banner: Yeah. It’s, again, on issue. Uhhmm – I think DIM is great for like, PCOS. It’s used a lot, you know, in some Estrogen Dominance cases. Also that CDG, I’ve known about just in the last year; that can help. Uhhmm – yeah , I’ve– in my own body has been more effective to build more hormone. And they did not be in everyone’s case. Maybe that’s just mine. And you can get tested. We have one. Maria Claps talks about the importance of testing at any age. And occasionally many women will be older but still have high estrogen, and that’s something to figure out and learn about. Let’s just see what pathways to – I think you run a DUTCH test too just to– see– like I was just curious about this caller like, what are her symptoms, does she feel – has high estrogen, and she’s worried about cancer in her family, or something like that. Yeah, I would say yeah, maybe but I want more information, or maybe they’ll be good to first person that ask.

Dr. Justin Marchegiani: I think you’re right. I think getting the test on, I think getting the more information on what the symptoms are that made them think they need it would really be the key.

Bridgit Banner: Yeah.

Dr. Justin Marchegiani: Next is…

Bridgit Banner: Question.

Dr. Justin Marchegiani:  Yeah.

Bridgit Banner: Love it.

Dr. Justin Marchegiani: Yeah we’re hitting it. Next is, without getting an organic acid test, is there a kind of a universal protocol supplement that can be taken for hormonal balance. What do you take personally?

Bridgit Banner: Well, I keep saying the same stuff over and over so, more, for me like, for me, definitely the oils. I love magnesium. I love, I love it for this age group. I love it in my own body, I used magnesium chelate. I, I like adore it, even when I’m just getting cramps. This stuff like helps me to prevent like menstrual migraine, menstrual cramps, uhhmm– you know. I take a good quality multivitamin that has, that has the Zinc, that has methylated B vitamins. And I’ll tell you a funny story. I got my hair analyzed like this sooner and I got the results back before but I got to read them. And like in my novice opinion, “Oh magnesium, it’s so high, I better like. Stop taki– a few things looked high.” So I stopped taking everything. I stopped taking. Oh, my gosh, my cycle. So much for stamina. It really made me see, like, getting a good quality source of B vitamins, B vitamins is very important to spark a bunch of things with ovulation hormones. Getting that is important. Taking the extra high dose. I mangled magnesium. Most women need like 600 to 800 milligrams and get in good form. I just have a new client and she’s been taking magnesium for years. I can’t remember the form she’s been taking but…

Dr. Justin Marchegiani: …oxide–

Bridgit Banner: Yeah something that she’s– I think it was oxide, she’s not getting anything out of it. So I just like said switch to magnesium. I love magnesium. I love fish oil, I mentioned. You don’t need a lot but a little bit. Uhhmm – a little bit of borage oil, or hemp oil. Uhhmm– you know, I eat a lot of nuts and seeds in my diet too, and I think they helped me from hormones.

Dr. Justin Marchegiani: Yeah.

Bridgit Banner: Uhhmm– what are the thing– we talked about Zinc, that if you’re not getting much Zinc it might be something you want to up the supplementation on…

Dr. Justin Marchegiani: Yep.

Bridgit Banner: …what other supplements do you like Justin?

Dr. Justin Marchegiani: I think, you already said the foundational things that aren’t even related to female hormones which I think gives people overlooked at, right? So that, what you said is totally foundation. Then add on top of that chase through your Vitex, that would be great for almost any female, especially for your cycling. If you’re more menopausal, you can go more on the specific pheno types of Maca. It’s a great product that I used and carry in my store called Femmenessence. And they have a great type of Maca for cycling females, and a great type of Maca for menopausal females, and it works phenomenal for a lot of cycling issues, and also about a lot of the Hot Flashes. ‘Cause remember Hot Flashes especially if they happen at night. They screw up women’s sleep. If their sleep’s screwed up, and their blood sugar’s screwed up, that throws everything off. So I like the Maca and the Chaste tree, you know. What’s going on.

Bridgit Banner: Yeah. You know, I, I have some. You know, I’ve used sleep aids, or like anxiety aids, you know, like now, on the summit, a lot. And I think it’s okay to this, at this age group. Like, don’t just like try to bear it, you know. If, you need to sleep, so you take some 5-HTP. I want a trick I’ve learned from my elevated practitioners, like, do some more almond milk and a half teaspoon of nutmeg. You know, that’s really calming at night. Uhhmm– what else do I take? You know I have, like, an herbal one – like valerian, stuff like that, which is calming. I have a whole bunch of things around to eat just depending on the day. Uhh – so, and that doesn’t exactly sound like it’s about hormones, but it kind’a is ‘cause you need that good night sleep to, like, get your hormones stabilized.

Dr. Justin Marchegiani:  Huge. What do you eat for breakfast, lunch and dinner, Bridgit?

Bridgit Banner: Oh, I love it. So this morning I have a cheap pudding and uhhmm – I have it on with some chocolate flakes, walnuts…

Dr. Justin Marchegiani: Nice.

Bridgit Banner: … glazed and on top some fresh fruit. So, uhh – I’m a little allergic to eggs so I don’t, you know, that makes – you know the word. ‘Cause I do a sausage, like, like a little frozen organic sausage uhhmm– Sometimes I have, occasionally I have, like, a soup for breakfast, like a – This can be super easy. You keep a box of broth in your fridge and like a teem of Kewas, some greens. Sometimes I have that. What else? I’m giving you breakfast ideas ‘cause I think it’s a hard one for folks. I do smoothie sometimes. Sometimes I help people do some trail mix. I do hard boiled eggs, so get some protein. I really avoid carbs in the morning. That’s very important to me. But I do have carbs usually on lunch and dinner.

Dr. Justin Marchegiani: Yep.

Bridgit Banner: For lunch, I sometimes have leftovers. I love working from home because I can have, I can turn things together, like some leftover rice, you know, fry some vegetables. Try to have like some chicken sausage, which I had laying around. Uhhmm – I definitely just kind of put stuff together, for pretty healthy lunch, uhhmm – which, yeah – I love that option. For dinner, you know, we usually have something like a piece of fish, or chicken, uhhmm – you know, often an animal protein, and then uhhmm – some green stuff, you know, a steamed broccoli or, I’m,  I’m putting a lot of fat and everything, so my steamed broccoli’s gonna have hemp oil all over it. I put hemp oil yeah, hemp oil, hemp oil on my lunch. I put hemp oil, you know. I put hemp oils everywhere, nuts everywhere, lots and lots of seeds. Uhhmm – and then maybe we have like sweet potato fries. So, we do some potato, some rice or Keema are pretty much the carbs that I would eat.

Dr. Justin Marchegiani:  Yeah.

Bridgit Banner: Uhhmm – what else? Yeah. That’s kind of the theme.

Dr. Justin Marchegiani: Excellent. I think you’re rock solid. Two other questions; we’ll hit them rapid fire. Does it matter for Dacogens be in pill form or powder form? It depends. Certain female hormone issues or tonics, I do find sometimes giving the liquid. Tincture-based herbs can make them a little more potent.

Bridgit Banner: Hmmm–

Dr. Justin Marchegiani: …a take on that? Do you agree or no?

Bridgit Banner: I would, yeah. That’s like a great question. I mean, I think the tinctures feel strong, but if you’ll take out a small sip of oil. If you take – I bought all this like powdered Maca and stuff to make these elixir drinks. I don’t like them. I don’t like to, you know, the powder in them. So, it takes some things… but I do have a Maca powder, I make them to smoothies. Effectiveness, efficacy, I’m not totally sure if, you know, I have to research that. But I do think it’s important to take what you’re gonna take. Have a variety. Like, I’m willing to take pills, ‘cause I’m pretty okay with it. But it’s nice to also have some things that are liquid. Some things that you can rub on, like, I feel, especially with my mold. I really learned, like, it’s. Uhhh– It  can get exhausting and so expensive to take so many supplements. And if there’s something you can do that’s in another form, I’m really holding on to that a lot sider lately. So I would just tell the colors rise efficacy maybe on home ingredients but I like things in all sorts of forms, and I think it’s good to experiment.

Dr. Justin Marchegiani: Yeah, I think it’s totally good to individualize. Last question, Cortisol is normal except spikes at a very high at around three(3) to five(5) PM. So this person wants to know, is that Adrenal Fatigue stage 2? Again, I think we did the whole test to see it, to know where the Cortisol levels are at. Stage 2 is typically, relatively, normal Cortisol levels, with aberrations and rhythm, and lower DHEA in general. So I think we’re missing some info. Any comments?

Bridgit Banner: You know, the thing that came to me, and I’m not an elevated practitioner. But is it, is it vital that wind one. That’s, that, that imbalance is in the afternoon, and that’s the time I feel imbalanced too. And a lot of people have this wind imbalance ‘cause we’re so busy nowadays, doing so much stuff. Uhhmm– so that’s like a really key time of the day for me to rest. And that can be tough ‘cause it’s like the end of your day, when you’re gonna pick up your kids. But I would just personally tune in to like how that time of day feels for them, and like what are they doing, what and where the stimulants were like, you know, just, are they eating snack always right before that spike, or in a certain stress trigger, or maybe the body’s just trying to like pick them up. ___?Slob?__ but not sure. I think it’s interesting there with three to five.

Dr. Justin Marchegiani: Yeah. I think potentially like a blood sugar drop, had their lunch around 11 or 12, maybe their blood sugar’s dropping so maybe they need a mini meal, maybe scheduled a meditation in there, maybe keeps an adaption …

Bridgit Banner: Yeah.

Dr. Justin Marchegiani: …kind of in your system during that time of the day; a couple of options.

Bridgit Banner: I have to eat at that time of the day. Like, it’s not optional for me, and the more I eat, the better. I mean maybe I should have my dinner there. Uhh – you know maybe someday I’ll also tea in that earlier dinner. But I, if I can really heavy snack. Yeah, my butcher, just dropping items, snacks constantly. One,  probably the one snack a day that’s not optional for me.

Dr. Justin Marchegiani: Got it. Perfect. Very good. Well again, closing up here. We got the Hormone Balance After 40 Summit. We’ll put information below in the YouTube description and the podcast description, so make sure you check out that summit. Forty (40), or thirty (30) years old, great people are gonna be there. I’m gonna be there in one of first days, so make sure you tune in to see me.

Bridgit Banner: Day one.

Dr. Justin Marchegiani: Day one.

Bridgit Banner: …this guy.

Dr. Justin Marchegiani: Love it, love it. Very cool. Any other comments or concern, anything else you want to address to the listeners or…

Bridgit Banner: No. I think that’s– it was a lot of fun. You know, I’m not always this, like, on my toes but it’s good for me. Just tried, tried to hang with it. There were really good questions. Then it was always fine with you Dr. Justin.

Dr. Justin Marchegiani: Thank you. What’s that summit URL link again?

Bridgit Banner: after40summit and it’s a number 40.

Dr. Justin Marchegiani: After forty, the number 40? Summit S-U-M-M-I-T? One ‘t’?

Bridgit Banner: Yes. Two m’s, one ‘t’. It should come up.

Dr. Justin Marchegiani: Perfect. Love it. Bridgit.

Bridgit Banner: Bye everyone.

Dr. Justin Marchegiani: Well, thank you so much for the great information. You have a great day.

Bridgit Banner: You too.

Dr. Justin Marchegiani: Thank you.

 

References:

http://after40summit.com/

The “Schwarzbein’s” Principle by Dr. Diana Schwarzbein

Natural menopause solutions live – Podcast #123

Dr. Justin Marchegiani and Evan Brand engage in a discussion about menopause. Join them as they share their expertise on women dealing with menopause, including the associated symptoms, hormones, and health factors creating an impact to this period.

Menopause is a naturally occurring transition in a woman’s life. It is a period wherein women undergo a lot of changes in their bodies. This talk will give you important information about these changes caused by hormones, including hormone function and drug interaction. Find out about the effects of infection, as well as other health related issues involving the adrenals, blood sugar and stress making menopause a more challenging experience than it already is. Learn about the natural ways and solutions to keep your health in check during the menopausal period.

In this episode, we cover:

6:26   Menopause: definition and symptoms

9:17   Adrenal gland and hormones

13:40   Conventional Solutions

17:08   Testing hormone preparations

19:31   Bioidentical hormones & herbs

29:20   Dietary recommendations

 

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Dr. Justin Marchegiani: Hey, there! It’s Dr. Justin Marchegiani, alright. I’m hooked on this Youtube live thing. We’re doing our podcast today, Evan and myself. So we are- So we talked about doing menopause uh, today. That was a topic I was listening and learning and reading a lot about it yesterday. I’m honestly dealing with menopause patient for the last decade but always brushing up on my info. Evan what’s going on, man? How you doing?
Evan Brand: Hey, I’m doing awesome. This is fun. Isn’t it great today?

Dr. Justin Marchegiani: It is. I love it. Very cool. So how’s your morning goin’?

Evan Brand: It’s pretty good. I still think that the, the best car for me is gonna be the Tesla because it is the HEPA air purifier in it.

Dr. Justin Marchegiani: Oh, nice. You in the market for a new car?

Evan Brand: Well the Honda Accord, I mean I love it, trust me but, taking in all those diesel fumes like I was telling you about even with the re __ on, I went over to the dealership and they were like, “Sir, you’re never gonna be able to block all of the fumes outside.” I said, “I will if I could have a HEPA filter.”

Dr. Justin Marchegiani: Totally, man.

Evan Brand: I think those Tesla’s are like biologically, like they put biological warfare down or something they will still be safe.

Dr. Justin Marchegiani: Yup, yup. Crazy. Oh, we’re live today. And we’re gonna be chatting aboutmenopause which is an exciting topic for me. I love my menopausal female patients because they’re really motivated. Number one, uh they need a lot of help. Number two, in the conventional medical options for them is pretty poor. So, yeah.

Evan Brand: I’m excited to be able to help. Yeah. Totally.

Dr. Justin Marchegiani: And we got a live chat going in the background which is exciting. So people wanna ask some questions. We may interject here and go live to some of their questions. That’s really exciting, too.

Evan Brand: Where shall we start?You wanna go over symptoms? Talk about- what, I mean most women if they’re dealing with menopause, they’re gonna know about the symptoms but people listening you know- Hey, Butter. Sometimes-

Dr. Justin Marchegiani: She’s Independence. She’s my biggest fan.

Evan Brand: Awesome.

Dr. Justin Marchegiani: Actually, my wife’s my biggest fan. She’s probably second.

Evan Brand: Sometimes you know- whatwe’ll find is with women you know- if they get their ovaries removed, they’re basically gonna skip perimenopause or just gonna go straight to full-blown menopause. Which is what’s happened, for example with my mom, getting the full hysterectomy, for example. You know at 40 something years old, she had already been put into full-blown menopause, basically. And so, she was experiencing a lot more symptoms a lot more rapidly. And say a woman who’s naturally gonna transition.

Dr. Justin Marchegiani: Totally. I have to say, Evan. Honestly, I’m mesmerized by that chest hair that’s coming out, man. I’m sorry.

Evan Brand: I know.

Dr. Justin Marchegiani: I was just like “Whoa! okay.”

Evan Brand: Can you believe that?

Dr. Justin Marchegiani: I know.

Evan Brand: I just actually, I just, I just show my wife last night and said,“Babe, this thing is growing north right now.”

Dr. Justin Marchegiani: Absolutely. Well on hormones, you know- hair,or hair growth will be a big connection with that. So we can chat about that today. Very cool.

Evan Brand: First thing, I need to button up this extra button here, so I’ll do it.

Dr. Justin Marchegiani: I don’t know, man. It’s gonna be really hard for me to pay attention during –

Evan Brand: Alright, alright. Let me button this up then. I apologize for my manliness.

Dr. Justin Marchegiani: No. You’re good, man. You’re good.

Evan Brand: Alright. Go over symptoms. What should we- I mean hot flashes are gonna be very common. Of course, everyone’sgonna know about hot flashes. They’re probably bored of hearing about that. But something that we see a lot, too is depression and mood swings. Something that could definitely be fixed if we take a look at the adrenal glands. And I guess were to hit on that adrenal connection, too. Because the backup generators, which are the adrenals, which should hopefully be kicking in and supporting women. A lot of times they had adrenal fatigue already. So when the ovaries and hormones go down, the adrenals are already tanked. So you’re not gonna have that backup generator that’s gonna help you out.

Dr. Justin Marchegiani: Exactly. I’d say the big is, let’s define menopausal a bit more. So menopause is that time where typically the ovarian function, the ovarian output of hormones is-is running low. It starts to get depleted. And that’s typically because the follicles that a woman is born with, they start to run out. So a woman typically has you know, hundreds of thousands of follicles at birth. And then eventually, only maybe 400 or so are viable. So you fertility for a woman typically, let’s say on average, is gonna be from maybe 13 to 15, depending on when they have their period at first all the way up to the early to mid 40s. Some even late 40s uhm, today as well. So that’s kinda like your- your viable uhm, window for fertility. So when those eggs start to run out, and what starts to happen is your ovarian function starts to diminish. And then that typically, it’s about, consider it about a one year time frame until you actually get in to uh-menopause. That’s the perimenopausal timeframe. It’s about one year until you- One year without a period is what you consider to be menopause. And obviously if you get a, your ovaries removed, like hysterectomy wise, obviously that’s instantaneous menopause, right. Coz you’re missing the hormone output. For most women it’s about 12 months about a cycle. And that’s when you technically hit menopause. And then menopause typically can last until you’re instantly postmenopausal. Can typically last about 10 years. So that can kinda scare some women. And if you get your universal move, like a partial hysterectomy- you keep your ovaries but you get your uterus removed- women typically will go through menopause about four years faster. So the uterus does have some hormonal interplay. So again, because you- let’s say have a partial hysterectomy and still have your ovaries, you still will go through menopause. And it’s important that you get that support. And a lot of women they get their uterus removed. It’s typically because, maybe endometriosis or severe fibroids, or some kind of excessive hemorrhage, or bleeding. They cause them to get removed in the first place.

Evan Brand: Well even I’ve heard of some women saying just because they don’t wanna have a period anymore and doctor will still do the surgery.

Dr. Justin Marchegiani: Yeah. That’s not a good move because your uterus does have some effect on hormonal output. Again the research and people don’t quite have their head around it, that you have, around hundred percent. But there’s still a reason why that is there. So the first aspect is you know, the definition, one year without a period. That’s number one. Number two we have that perimenopausal timeframe, which is about 12 months. And then once you’re in menopause, about 10 years until your technically postmenopausal. Now all the symptoms that we talked about earlier, what are they? There gonna be hot flashes, of course, right.There gonna be mood issues, lack of femininity, right. Feeling less like a female, less like woman, uhm called the sagging breasts. Uhm, I would say a little loss of elasticity in skin. As your estrogen drops, that can shrink breast tissue. It can also stimulate or decrease the stimulation of collagen. So the skin starts getting- losing that quality, and that elasticity, and that nice healthy useful tone, hair loss, mood issues, brain fog, osteoporosis, obviously vaginaldrynesss, depression. So these are all symptoms of the ovaries losing their ability to function. And then what starts to happen is your adrenal glands really have to pinch-hit and come to the table.

Evan Brand: Yup. So if you got infections or your adrenals are tanked, when the- if we use the pinch-hit term, they’re not gonna be able to doit very well because you’ve got these other problems. Or the diet is not good, you’ve got blood sugar swings. So without healthy blood sugar, it’s gonna be tough to have healthy adrenal function.

Dr. Justin Marchegiani: Exactly.

Evan Brand: You know the thing that’s interesting is a lot of women get talked to about menopause like it’s a disease. But it’s not really a disease. It just seems that the modern world in terms of either too much or too little exercise, and a diet that’s not rich in good fats and good proteins, those are the modern things that we’re up against. So menopause is becoming more prevalent. And then also, it’s gonna be more severe, too. Because our ancestors they’ve dealt with menopause. You know, this is a natural transition, but now we’ve- were up against these new things that the modern world present. So therefore, we have to play the cards a little bit smarter, make sure we’ve got the nutrition down, make sure we’ve got the exercise portion down, and then we always get to the underlying issues that could still be affecting things or making things more intense. Like say, an infection which you and I find hundreds and hundreds a year. And menopausal women, a lot of times there is adrenal issues calls from infections.

Dr. Justin Marchegiani: Absolutely.And to- I wanna add, we’re actually doing this podcast live. So anyone watching live right now, feel free and write in a question or two. And we’ll be able to see if we can intermingle the questioning with the podcast. Sothis is gonna be this kinda new little set up here. If people are likin’ this, we may do more of it. So we’re pretty excited about it. I did a couple YouTube lives this morning and people want a couple questions answered. But still do it as long as we can get a turn into the topic.

Evan Brand: Yup. So-

Dr. Justin Marchegiani: I got a little Kombucha right now. I’m getting my ginger Kombucha in here.Nice.Love it, love it. Nice.

Evan Brand: I’m drinking uh, Vitamin C actually right now. Vitamin C tonic out ofout of little mug that says having tea with a friend brightens any day.

Dr. Justin Marchegiani: Here, here. Touche on that one. Excellent. So we talked about hot flashes a little bit. Can you talk about- Can you go into like, the adrenaland why the adrenals are so important for women that are getting ready to go into menopause?

Evan Brand: Yeah. Absolutely. Well so, if we look at the top of the food chain of hormones, if you type in steroid hormone pathway chart online, you can see where cholesterol, which is going to come from diet. Also of course the liver and all of that. But you got cholesterol at the top of the food chain here. Then downstream we’ve got progesterone. You’ve got pregnenolone. You’ve got your estrogen, your estriol, your estradiols, your testosterone, your DHEA’s. You’ve got your aldosterone. You’ve got cortisol. You got all these hormones that are depending on a pretty good balance. But as we pry talked about before, what happens is the pregnenolone steal, some people debate that. Some people say that it’s not true. But just based on what we have done, and what we do, to me it makes perfect sense of the pregnenolone steal is perfectly real. Which is the process where men and/or women that are under significant stress, the body is going to prioritize cortisol production over the production of these other hormones like your estrogens. And so when menopause is occurring, and the levels of estrogen and progesterone are dropping, now you’re just dependent on the adrenals and this cortisol, this whole adrenal cortisol- and I guess we’ll call it backup generator- to do the work that was being done by two generators before. Now you’ve got one generator doing the same amount of work. Now, if you’ve already been in sympathetic fight or flight mode, for significant amount of time, you’re gonna have trouble. So when we pull your adrenal cortisol results, we’re gonna see that you’ve likely got low free cortisol. Which means since you’re not outputting the amount that you should be. So the analogy I use is the smartphone. So a lot of women where looking at, they could be, we would like to seem around 28 or 30 units of free cortisol. I’ll make a bio health test, for example. But a lot of women are showing up anywhere say 10 to 15 units of cortisol. So that’s like you starting your day with your smart phone battery charged at 50%.

Dr. Justin Marchegiani:  Yeah

Evan Brand: And you’re trying to get through the whole day. It’s gonna be tough. And so this is why having healthy adrenals and having a good adrenal protocol in place, for me is essential not only for men and women that are you know, younger. But older women especially are going to benefit from some of the adaptogens and strategies that we can chat about.

Dr. Justin Marchegiani: 100%. Now, looking at the adrenals, I always thought patients are like a backup generator, right. They’re gonna produce a significant amount of DHEA which can go down the hormonal cascade and can become testosterone andro and primarily at a female, we’re gonna go down more of the estrogen pathway. So if you look at testosterone andro it can also float downstream into either estrone, or estradiol estrone, and estradiol.And then from there it can get converted in the liver to estriol. Estriol is gonna be about 80% of all the estrogens in your body will be estriol. During reproductive age, estradiol will predominate as your main estrogen. And then when you go into menopause, estrone will be what predominates when you’re menopausal. So let’s break that down. We have E1, E2, E3-really simple. The names have a good giveaway. Estrone has O-N-E in it. So that’s E1. Estradiol, D-I, right. like 2 dice, E2.And then estriol, T-R-I, that’s gonna be E3. So you’ve E1, E2, E3. E1, estronethat predominate when you’re menopause. E2, during reproductive age. E3 will be what’s there the majority of the time. Uhm- but it’s weaker, and it will significantly predominate when you’re pregnant. So what happens is when you’re going to menopause, E2 starts to decrease, and we start to get more dependent upon the E1. The problem is E2 and E1 are stronger estrogens and could be proliferative. Meaning, they can increase risk of cancer and other health issues. So, if we are gonna support a female with some bioidentical hormone preparation- Bioidentical meaning the hormone molecule matches what’s in your body, typically plant-based.We’ll do it with estriol, E3. And we’ll even typically combine a tiny bit of progesterone in there to support the female hormones.

Evan Brand: Should we talk about the conventional solutions,like hormone replacement therapy? Like the one that comes to mind here about a lot as Premarin?

Dr. Justin Marchegiani: Yeah. But yeah- yet but you Prempro or Premarin Provera?

Evan Brand: Yeah. I mean- That’s- that’s it. That’s linked with increased risk of heart disease now.

Dr. Justin Marchegiani: Yeah, in cancer- I mean the women’s health initiative study uhm- found that about 10-15 years ago. So it’s- it hasn’t been prescribed as much for hot flashes and menopausal symptoms. But it’s still is being prescribed. Their more natural, kinda anti-aging doctors are out there, typicallymedical-based. They’re prescribing hormones. The problem with it is they prescribe like it’s candy. They prescribe it like it’s a vitamin or nutrient. And hormones are really, really powerful, right. Hormones are measured in like nanograms, which is like one speck of salt in like a swimming pool, right. So it’s like very- you know- very, very sensitive. You know, amounts of these things. So looking at hormones, we wanna make sure we don’t give it like a supplement. We wanna make sure we actually test. So, we’re not guessing when we prescribe it. It’s specific to what the patient needs. Number two- number two, is we actually have to make sure the diet and lifestyle is dialed in coz that’s a really, really important starting point. And I would say even more important, most medical doctors or bioidentical doctors totally ignore the adrenal portion of that. So the adrenal is just totally not even on site. And we know how important the adrenals are for that backup generating of the sex hormones, especially when you on menopause. So imagine that backup generator, if it’s on empty, or the smartphone analogies on low, that means symptoms. So you gotta turn the generator when the storm comes in, it’s not on full. Guess what? Your power is not gonna work. There’s gonna be a lot of things in your house aren’t gonna work, like you have full power. And what that equates to a menopausal female, is symptoms. Mood issues, skin issue, hot flashes, of course, vaginal dryness, low libido, right. So those are the things we gotta be very mindful of, when we’re dealing with menopausal females.

Evan Brand: Let’s talk about what the options are. I mean even if you do go bioidentical, a lot of times you’re going to get hormone creams. But the more, more that we develop hormone creams, I’m finding that- that can disrupt other hormones, and it’s gonna be tough to measure, it’s gonna to be tough to get the right dose. And so now, I’ve been reading a lot about sublingual drops- for bioidentical hormones. Supposedly, that’s the best because you can determine exactly what dose you’re taking. For me that goes out of my- you know, that goes out of my pay grade coz I’m not a prescribing medical doctor. But it’s at least good to know that there are options out there for women because if they are going to go talk to their endocrinologist, or you know- some type of MD that’s more integrated. Hopefully they can know that, you definitely don’t want to go oral, you definitely don’t want to go with the cream. But if you can go sublingual drops, with the bioidenticals. However, in a lot of cases, if we are getting the diet dialed in, orgetting like some omega-3, fatty acid supplements in, we’re removing synthetic estrogens, the plastics, and all the other exposures, the phthalates, and all the other endocrine disruptors, and health and skincare products, and then we’re addressing underlying issues, I’ve had great success with many women- women. I know you have, too. In- we’re not- we’re not saying,“hey, go get this drug”, “go get the struggle get this prescription”

Dr. Justin Marchegiani:  Exactly. So when it comes to hormone preparations, number one, how do you test it?Most medical doctors they’re gonna primarily use a serum bound test, a serum blood test to look at hormonal levels. Now the problem is, serum represents a 100% of all the hormones that are in your blood, right. The problem is only about 2% maybe 2 to 5% hormone’s a free fraction. So the problem is because a small- for such a small small percent of the hormones that are free, it’s such a small percent out of the hundred percent. It’s really hard to measure it because you don’t have a small enough gauge to sense it.

Evan Brand: That make sense.

Dr. Justin Marchegiani: So it’s like using a thermometerthat only tells youyou’re either 97- 98- 99.Doesn’t tell you the in between temperatures. So your 97-9, it may say you’re still 97, right. So imagine that’s kinda like the blood testing. So we use a free fraction test that will break it up and look at the free fraction of the hormone. Whetherwe’re using bio house salivary cortisol, or salivary progesterone or estrogen test. That’ll look at the free fraction. Or we use the Dutch testing, that will also look at the free fraction. Excuse me.The Kombucha gets uh- gets me a little bit burpy.

Evan Brand:Ha ha

Dr. Justin Marchegiani: I apologize for that. Uhm- so looking at that, we will wanna do tests that look at the free fraction. Number one- so salivary test or like a really good Dutch test by Precision Analytics is great. Because we get a more fine two-metric of where those free fraction of the hormones are at. Again, there are some blood tests that can- I think you can look at estradiol-free. I don’t think you can look at progesterone-free or cortisol-free on a blood test, yet. You can look at serum cortisol, you- you can look at estradiol-free, you can look at testosterone-free. I do not think you can look at progesterone-free. So again, we wanna be able to look at the free fraction coz that’s what bioavailable and combined into a receptor site.

Evan Brand: Yeah, I wanted to mention the- Dr. Jonathan Wright, which- I believe it’s the same- it’s the same guy who wrote the book on stomach acid, which is I know one your favorites on my favorite books.

Dr. Justin Marchegiani:  Yup.

Evan Brand:  That he’s got some good info with Mercola about administering bioidentical hormones. And are talking about the version that they call tri S, which is supposedly 80%, estriol, 10% of each estrone and estradiol. So it sounds like- for even you know people like my mom, any woman that’s had you know- a full hysterectomy, it sounds like this is gonna be pretty foundational to- to overall health. It sounds like you can’t really out supplement your way if you have had you know- a full hysterectomy like this. What’s your take?

Dr. Justin Marchegiani: Right. Remember what I said? I said 80% estriol, right. So think about it, right. With a tri S, what is it? 80-10-10. 80% E2- I’m sorry-E3, estriol that’s the tri S. So 80% estriol, E3. 10% estradiol and 10% estrone. And that’s good if you can get it compounded that way. That’s fine. Again it’s still gonna be a cream and the problem is some women don’t do well with the cream because it super saturates in the subcutaneous tissue and starts coming out in uncontrollable amounts. You don’t get dosed into the bloodstream as efficiently let’s say, as a sublingual. They can go right into your sublingual tissue in your buccal tissue, go right to the blood, and there’s no like real fat in the mouth. Soright in there, and your good. Now the differenceis Dr. Jonathan Wright’s talked about this. If he does sublingual’s- I’m sorry-If he does the creams, he typically does it inter vaginally because of the submucosa down there. They can go right into the bloodstream. So that’s helpful. But again, you know, I’ve dealt with a lot of women that do the creams and such,inter vaginally, which can work decent on menopausal women. Not so much on cycle, and I’ll tell you why.But again– it’s some issues issues. I mean not to get too graphic here, you can get to the underwear, you can come out. Uh- it’s okay if you can do it at nighttime when you’re lying down. But sometimes you get discharge and they can wrap women’s underwear. They can be a little uncomfortable. So it just depends on what you like. If women have already done that- done it that method. And then they’re doing well, and the hormones are stable, and they didn’t have any of those issues that I mentioned, fine. If not, we’ll typically recommend some of the sublingual drops. Some of the estriol and/or progesterone drops. We’ll also support the adrenal glands themselves. And then will also use some specific herbs to help modulate the sex hormones. We’ll use wild yam. We’ll use chaste tree, or vitex. We’ll use dong quai. We’ll use black cohosh. Uh- we’ll use some of those herbs to help modulate the receptor sites. I’ll even use some specific phenotypes of mock guys. Some specific phenotypes for cycling women and/or menopausal women that- that will help with even some of those symptoms of the receptor site level, depending if we have a cycling or a menopausal issue.

Evan Brand: How about soy during this time?

Dr. Justin Marchegiani: Well if you’re using specific soy isoflavones, that can be helpful to modulate estrogen receptor sites. Again, we’ve talkedvery negatively about soy, but again soy if you extract the isoflavones, you’re also not getting all of the proteins and the  in the goitrogens, and the trypsin inhibitors. All of the negative effects. And of course, it’s gonana be extracted from a non-GMO source. So my opinion, you can still get some significant benefits. But where it’s the genestein the other types of soy isoflavones can be helpful for modulating, yes, receptor sites.

Evan Brand: Sure, sure. And I briefly mentioned omega-3’s but that’s another good one. Just plenty of omega-3 fats so good, high-quality triglyceride form of fish oils, which is what you and I use. So if you are takin’ a fish oil and you get fish burps, it’s probably ethyl ester. And that’s not good. If it smells fishy, most of the time,that’s not good, either. And you want to-

Dr. Justin Marchegiani: You want the triglyceride form.

Evan Brand: Yeah.

Dr. Justin Marchegiani: That’s it.

Evan Brand: Which is basically is as close as you can get to the raw form or the form that you would get if you’re just actually eating the fish.

Dr. Justin Marchegiani: Absolutely. So looking back at all the different things we talked about some herbs to help modulate receptor sites. We talked about using potential bioidentical hormones, our biases more towards the sublingual. If you were to do intravaginal cream, if have to be intravaginal, ideally not on the skin as much. Because of the super saturation in the subcutaneous tissue. And I see it on test. When you see like literally women are off the charts. You’re like, “hey, your doctor’s just measuring blood.”And because it doesn’t have a small metric to pick up that unit 2% or so, it may look okay in the blood, but not the okay in reality in- in the spectrum of looking at the free.

Evan Brand: Yeah. I’ve seen that, too. I’ve seen it with men, too. Which is all other conversation but testosterone replacement therapy, where just go so far above the 6, 6000 about 6000. That’s like where the test maxes out. And its like, “whoa! something’s not right.”

Dr. Justin Marchegiani: Exactly. Now, looking at cycling women, why do I wanna avoid creams altogether? Well for the most part with cycling women, their hormones are gonna be at different place in the cycle. The first half of the cycle is gonna be the follicular phase, where estrogen starts to go up around day 2. Day 3, it taps out around day 12 to 13. And then it drops as progesterone rises. That’s where your ovulation is.That estrogen drops and progesterone rise is where ovulation is. Progesterone comes up to the top. Estrogen nears down low and they both dropped together around day 27 and day 28 to signal bleeding. And again, the reason why this is an issue is, because if you if you can’t pull estrogen or pull progesterone all at the right time, then that can throw off the cycle. Because if estrogen and progesterone aren’t dropping exactly when it should, you’re not gonna have adequate menstruation. It may delay things. It may slow off your cycle. So because of that, I don’t like creams on my cycling female patients. I like to be really specifically progesterone exactly what days. I don’t want any spillover on either end. And I typically don’t use any estrogen with female hormone patients that are cycling because most women are estrogen dominant. And will typically be able to support the estrogen via the adrenal side via some of the DHEA and pregnenolone and some of the modulating herbs.

Evan Brand: So if you went to a standard MD or like an integrative MD, are they can be able to provide those sublinguals? I mean- how common is that? I know were talking about- sometimes we talk about subjects where the optimal thing is just unheard of in conventional. But I mean- is this sublingual, is this popular enough for some woman could go down the street to a clinic and get- get help with that?

Dr. Justin Marchegiani:  Uhm, most conventional medical doctors aren’t gonna- aren’t gonna be able to do the sublingual coz it’s just not in their wheelhouse. Uhm- some do troches which maybe a close second, right. A lot of them will do the pellets, and then most of them will do the creams. Just how they’re taught. You know, if you look at a lot of the ___, some of the anti-aging physicians, they’re gonna do more the creams. Dr.Jonathan Wright does this, but at least respect that it’s intravaginal. So you don’t have the subcutaneous build up. But again, I think the more important piece here to look at, is the adrenal aspect. We gotta look at the adrenals. And if anyone’s viewing right now, and wants to chime in, and ask a question via chat, feel free to do that. And we’d love to answer any of the questions that are on or related to the topic. This is a new thing we’re testing out. So the more people that engage or comment on this afterwards, that’s gonna motivate us to do more of these.

Evan Brand: Totally. Yes. So, the- you’ve hit on the good point, which is, yes- you can go there with the hormone replacement therapy. It has done good things. It can do good things, but I’m not prescribing it and I’m getting- I canprescribe but I’m not a prescribing MD. But just doing the stuff that I’ve done, I’ve been able to make 80, 85, 90% better in terms of symptoms that menopausal women are experiencing. And that’s with no drugs. That’s looking at the adrenals, that’s getting the gut infections taken care of, that’s looking at mitochondrial health, that’s getting rid of candida problems, that’s making sure they’re going to bed on time, that’s making sure they’ve revamped any type of cleaning products in their house. They’ve got the chemicals out, they ditch the plastic Tupperware’s. So all that stuff your adding 5%, 10%, 15% and then it just keeps adding up and then eventually, people are gonna feel much, much better.

Dr. Justin Marchegiani:  Oh, absolutely. And I think the bit thing is you’re working on the adrenal piece like I mentioned. You’re also working on the diet, right. Your stabilizing blood sugar. One of the biggest stressors on the hormonal system is going to be blood sugar swings. The more you stabilize those blood sugars and keep that dialed in, you’re gonna takea lot of stress off the hormonal system. Also stress is gonna eat up progesterone. So kinda like the pregnonolone steal, which is you know-it’s theoretical. It makes sense. It’s just- Here’s howI tell patients. We’re prehistorically hardwired to allocate our resources to stress and inflammation now versus healing and recovery in fertility tomorrow. Why? Why is that? Well because if we don’t get through now, tomorrow never comes. So it’s like the 12-year-old boy procrastinating on the homework. If you’re chronically stressed, you keep on putting off the fertility in the recovery, in the- the recuperation that is needed. So we’re chronically hardwired to deal with stress right now. So the goal is to decrease that stress, so then your body can start to allocate that, and put the healing and recovery in the fertility higher up on the priority list.

Evan Brand: Well said. Yeah. And it’s crazy to me how you can go and you could complain of the symptoms up sounds like you’re in or you’re going to menopause.Here’s cream and have a nice day. And none of this other stuff is discussed. I mean, we’re looking at massive pieces of the pie that are just completely ignored.

Dr. Justin Marchegiani:  Oh, yeah. Absolutely I would say the biggest issue I have when I was at the menopause summit last week with the with uh- with Bridget- Bridget Dainer, and one of the things they came off that we talked about was, I would say, one of the biggest things that is driven more menopausal patients to me, is this low-fat era. Avoiding animal proteins and healthy fats because that’s where a lot of your hormones come from. So if you don’t have that diet piece dialed in with the hormonal substrates, and the building blocks, and the healthy amino acids, you’re really at a significant disadvantage to being able to make your hormones on your own. So healthy fat-soluble nutrients, through grass-fed meat and Pasteur-fed meat and Pasteur-fed eggs, organic, free range, none of the chemicals. You don’t wanna add more Zeno estrogens in our meat to the- to the table, right. And throw off our hormones more. Healthy fish, egg yolks, if you can handle grass-fed buttering ghee, that’s great. Lots of vegetables, a glycemic or carbohydrate uh- balanced meal for you. So depending on starch, or no starch.Keeping grains out, keeping inflammatory foods out, keeping toxins out, and stabilizing your blood sugar, or not letting your blood sugar drop and not letting yourself get hungry is gonna be a great starting point for most people.

Evan Brand: Yes, I mean vegetarians, vegans specifically for women at this time, it’s gonna be brutal on them. If you’re vegetarian, vegan and you’re going into this phase in life, it’s gonna be really, really tough on you.

Dr. Justin Marchegiani:  It definitely will be now. If you are in that place, you know- I would try to coerce you in- and sell you on the fact that you probably want to eat some of these healthy animal proteins. At least cajole you and maybe some egg yolks, or tiny bit of fish, if I can do that. If I couldn’t do that, I will at least try to get you on some collagen proteins, uh- some really good P-protein. I’d even recommend you get some free form amino acid supplementation. I recommend lots of healthy fats via avocado- avocado oil, coconut oil. I will do Chia seed. Uhm- again, olive oil, low temperature. AndI would really work on the good fats, and I would make sure not going excessively high in the carbs. A lot of vegetarian by default become carbotarians. Again, I got in a lot of flak on this on YouTube, but it’s true. I’ve looked at hundreds of food logs of these types of patients and people. And I’ve seen it over and over again. The difference between me and you Evan, and the general public, is most people in the public, they only have an N=1. They have a torr experience. So if they extrapolate themselves, as is what everyone does, we seen it many, many hundreds, if not thousands of times over, most vegetarians become carbotarians with the grains and the excessive starch. So again, may not be an issue for you. I may not be speaking to you directly, but again that’s an issue that we do find on the vegetarian side.

Evan Brand: Agreed. Yeah. And we can look at the lab results, too. And I notice YouTube is the place where you get the most hate comments about vegetarian or, or- or veganism. If you’re- if you’re saying that that’s not a good- not a good thing to do, but we got the lab results to prove it. So when you got people out there saying look at this person, or look at this one doctor, or look at this one study, it’s like,“Hmm, I’m gonna look at the stuff that we’re doing in the trenches. I mean,  you and I are in the thousands of people that we’ve worked with now. And we see the direct correlation where when people start adding in the eggs, or they start adding in the good fats on a retest of let’s just say, adrenal cortisol pattern, for example. We may notice that the cortisol could get back into a good rhythm. Now granted there’s lifestyle components that were helping, there’s- there’s stress management, there’s the sleep, there’s the watching off of the blue light, etc. Getting good bright light in the morning, which is gonna be helpful. If you’re spending time in a dark room, cortisol is a light driven hormone, so if you’re waking up and you’re not opening the blinds, that’s a big issue, too. Wearing sunglasses, for example, but if your adrenals are stressed, you’re gonna want to wear sunglasses.  Some women they’re complaining of a bright light coming in, you definitely wanna get your adrenals tested. Because I’ve noticed that people I suspect- like I look around my family to see,  “Oh, I bet she’s got some adrenal issues”,“she’s always wearin’ those sunglasses”. That gets better when we support the adrenals. Bright lights don’t bother you as much.

Dr. Justin Marchegiani: Absolutely. That’s a 100% true. I totally agree. Well, anything else we want to touch upon with menopause. We hit the adrenals. We hit the diet. We hit the blood sugar. We hit some of the supplementation. Again, some womendon’t necessarily need the bioidenticals, but some women do. And it really depends on what’s going on, how unbalanced the hormones are, and how bad their symptoms are. Again, the more their hormones are depleted, you may need a strong bailout, a fast bailout with a little bit of hormone support. So I don’t wanna keep my female patient suffering. So we’ll use a little bit of that. And as long as we’re testing, and were not guessing, were assessing, I feel very confident moving forward  with that.

Evan Brand: Agreed. Yeah. Well said. Well people let us know what you think of the live YouTube thing. I’ll be curious to hear the audio quality. I mean, you talking to me it sounds- it sounds perfect. So if it’s as good as us recording through Skype, and other methods, then I say we could just keep doing our shows like this.

Dr. Justin Marchegiani:And again, we didn’t plan uhm- to do this show today. So I did one this morning off the cuff. I posted last night. So we had more viewers, but today was off the cuff so we don’t have too many viewers listening. But if anyone’s listening and wants to ask any questions, let us know. But I plan on- we’ll probably have hundreds, if not thousands, of people listening live very soon. When we start planning these out and it we’ll put it out in our emails. We’ll put on Facebook ahead of time so people know and they can come with your questions. Bzut anyone has any questions, actually we got a question here.What about liver health? And where to metabolize estrogens? Yeah. So regarding estrogen metabolism, this is important because I mentioned this earlier. We had E1, which is estrone and we have E2, which estradiol gets funneled downstream into estriol, okay. And what happened- this conversion happens to be at the liver. So E1 to E3 and E2 to E3, all happens in the liver. So anyone that has a liver issue, is gonna have a female hormone estrogen issue. So we wanna work on the liver. And also on the Dutch testing, we’ll look at the 2- hydroxyl, the 2-methoxy estrogen metabolism and we’ll look at the methylation meter and see if we’re having that one-to-one ratio of estrogen metabolism. So for 2-hydroxy estrogen of 1, do we have a 2- methoxy 1? Do we have this one-to-one metabolism? And that’s the methylation meter that we’re looking at on the test. If not, we could be uhm- essentially not getting rid of all the ashen. We could be re-absorbing that. Also, increase estrogen issues are gonna cause gallbladder issues. So again, you know- that the FFF role gallbladder issues, women that are overweight or fat, women that are- that’s the FFF, that’s just the accrued abbreviation. So overweight female, and 40 or up. So that this estrogen dominance thing. This is what goes, you list- I mean- I remember sitting in the many gallbladder surgeries, and those like FFF. Those are the three things the surgery would say. Are your overweight, female and over 40? Because the high amount of estrogen dominance, right. Makes the gallbladder- makes the bile flow from the gallbladder sluggish. So then what happens is two things. You can’t metabolize your hormones. A lot of that happens via the bile excretion. And then number two, you lose the ability to break down your uhm- fat-soluble vitamins. So gallbladder issues, and then fat metabolism, and then detox are common side effect of estrogen dominance. And that can happen leading into menopause. I can’t tell you how many of my female patient that are cycling have lost her gallbladder. And it really sets them up for nutritional efficiency and poor detoxification down the road.

Evan Brand: Oh, gosh. Well said. I mean- when I hear liver too, I just think of, like the GPL talks that you and I’ve chatted about with the gasoline additives and all these other chemicals in people’s bodies, aspirin and other- you know, pharmaceutical medications that increase the burden on the liver. So whether it was like statins, or hard drugs, or any of the stuff that that’s really tough on the liver. Alcohol, which a lot of women over 40, their stressed, they’ve got these symptoms, so they’re using wine you know, to put themselves to sleep. A glass or two a night which could increase the burden on the liver and messed this whole process up. Plus we’ve got parasite infections. You know 1 in 3 is what we’re seeing of infected people. Say you’ve got the toxic load there. And then if you got methylation issues, like you’ve mentioned, and you’re unable to detoxify, or you’ve got problems with the phase I or the phase 2. And you’re not taking something to conjugate those toxins and rattle them up and get them out your toes. So there’s a lot of different pieces that- that can be improved upon, for sure. Sço we always factor liver in. It’s not a matter of if we factor liver and detox into the protocol, it’s just a matter of when.

Dr. Justin Marchegiani: Absolutely. Now we just say- making sure we- you toss upon earlier with the gut stuff and I think so many mainstream functional medicine practitioners, and I would say even the medical doctors, ignore the digestion part coz again, a lot of the detoxification happens with sulfur amino acids. So we have to make sure we have the sulfur amino acids, the phase 2 sulfur amino acids to run those liver pathway. Socysteine, glutamine, glycine, and the glutathione precursors uh- methionine, taurine, especially for the gallbladder, are gonna be super helpful for liver detox. Also making sure we eat a lot of the cruciferous vegetables. And again, if you have gut issues, make sure they’re cooked so the fiber’s broken down. So we can get the diindoylmethane and indole-3-carbinol, which is gonna be really important for estrogen detox. And again, this is your broccoli, your brussel sprouts,your cauliflower, your asparagus, your kale, spinach

Evan Brand: And your broccoli sprouts. I love broccoli sprouts.

Dr. Justin Marchegiani: Yes, broccoli sprouts. And again we have someone answering uh- or asking this question live. So we’re answering anyone else that wants to ask a question live. We’re both ready to sign out. So anyone else,uh- put something in the chat window, we love the answer to it. So to finish that question, what other herbs can we give? So for gallbladder, we wanna add maybe some extra bile salts. We wanna do some fringe trees, some artichoke roots, and phosphatidylcholine, some X taurine. These are great for the liver. Extra milk thistle, silymarin. These are great things and we may even give extra sulfur amino acids, antioxidants, B vitamins, extra folate. These are all great things to support the liver. And I’d also say make sure you’re not doing all the bad things regarding the pesticides, the chemical, the exogenous hormones. And again, this is where a little bit estriol may need to be given coz that if we have toxic liver, we may not be able to have that liver conversion goin’.

Evan Brand: Well said. Great job.

Dr. Justin Marchegiani: Excellent. And we have a couple of other questions here. Uh- No, I did not go to the Super Bowl. No, not this year. It’s in Houston. I was thinking about it, didn’t make it down there. But I’m a huge Tom Brady fan. I think I know a lot of haters for that. But Tom Brady is the poster child for functional medicine, natural medicine. And the guy’s 40 years old and better shape than ever. And part of it is because of his diet,his eating,his sleeping, his training he sees a chiropractor, he sees an acupuncturist. The guy’s dialled in and is using natural medicine and functional medicine as his go to and not conventional medicine for his go to. So,huge fan of that. Anything else here, Evan?

Evan Brand: I don’t think so. Some people back to the website, check out Justin,  justinhealth.com Check me out notjustpaleo.com or type in Evan Brand. You’ll find us both. More content, more info, the ability to schedule consults with us. All of that’s there. So we do both offer 15-minute free call. So if you got questions, you wanna get your questions answered, reach out. You know, there’s no sense in suffering if you know that there’s a possibility to get better, go for it, time’s wastin’.

Dr. Justin Marchegiani: And if you guys listening, like this type of format, we want to do it more frequently. So give us- give us some love,give us the thumbs up. Uh- share it, put it on Facebook, email to your friends. We absolutely love it. And the more feedback we have, the more we wanna do this.

Evan Brand: Absolutely.

Dr. Justin Marchegiani:  Excellent. Alright, Evan. Well this- the beautiful thing about this is,this thing goes live right away.So kinda exciting, instantaneous feedback for the listeners. Anything else in your end?

Evan Brand: No man, that’s it.

Dr. Justin Marchegiani: Alright, man. Great chattin’.

Evan Brand: You too.

Dr. Justin Marchegiani: Take Care.

Evan Brand: Bye.

Dr. Justin Marchegiani: Bye.


Reference:

notjustpaleo.com


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