Optimizing Your Functional Medicine Gut Program – Dr. J Live Podcast #164

In today’s video, Dr. Justin Marchegiani and Evan Brand discuss the topic of creating a functional medicine toolbox for your gut health. Learn about the natural ways to modify your diet, improve your digestion, and promote your overall gut health. Watch and listen as they reveal some of the tools in the trade.

Discover some protocols that help aid problems with gut fungus, yeast overgrowth and infection, gut bacteria issues and parasites in your digestive system. Learn about the different steps to take on how to ensure you’re taking the right path for better gut health. Also, stay tuned for more information about how to further catch some knowledge bombs from this functional medicine duo.Optimizing Your Functional Medicine Gut Program

In this episode, we cover:

03:30   Looking at the Food

04:23   Digestive Support

06:10   Silver in the Killing Phase

09:47   Probiotics and Antibiotic Therapy

13:48   Retest




Dr. Justin Marchegiani: Hey there! It’s Dr. Justin Marchegiani. Evan Brand, what’s going on, man? How are things?

Evan Brand: Happy Monday. Life is good. The sun’s gone, though. That’s sad. This time of the year just— gonna start that gray sky, so I’m kind of jealous. I’m sure it’s sunny in Texas right now.

Dr. Justin Marchegiani: It’s a little cloudy out here today, but I was actually in Lake Austin yesterday, water skiing. I got a new suit. It’s about a three-four millimeter kind of thickness suit, so it’s great. I go in the water, doing pretty good. I’ve got some little booties, too, that are neo-printed, and some gloves. The worst thing was the week before. I didn’t have the gloves— is you really— you know— ‘cause when you’re squeezing really hard, right? You kind of squeeze a lot of that blood out, right? You kind of like— you know, white knuckled, so to speak. You don’t have a lot of blood, so your hands get really cold with the air. So those new gloves made a huge difference

Evan Brand: Well, that’s awesome.

Dr. Justin Marchegiani: Yeah. How’re things going on with you?

Evan Brand: Things were good. You know, the baby’s running around and keeping me busy. She basically stole half of my lunch. She took all my carrots and almost stolen my peas, so that’s a lot of fun. You know, tweaking her diet. We just actually ran a GI Map on her. So, we’ll make it to Stool Test back. We’ll have to uhh— chat about what’s on there— Actually, no! I take that back. We got the results. She had Klebsiella on there. So, that’s pretty interesting.

Dr. Justin Marchegiani: Awesome, dude. I got my dog, Butter, here on the YouTube if you guys want to see her. Butter (kisses the dog). We love good healthy fats, that’s why we named her Butter. Uhm— but yeah— so, we’re in the same place. Aden’s doing really good, breastfeeding like crazy. He’s starting to sleep a little bit more, so we’re really excited about that. Really happy your daughter’s going good, too.

Evan Brand: What do you think about the Klebsiella with her? I mean, we’re using some herbs already. It’s like, at her age it makes you wonder. Did she pick up Klebsiella from somewhere? Did she have it? Was that passed through the placenta? I mean, it makes you wonder, her being that young.

Dr. Justin Marchegiani: Yeah. I mean, I would say off the bat, uhm— probably something from your wife? From you guys? And, I would utilize some probiotics and, maybe, one oil of Oregano Capsule a day, or something like that, or maybe decent to help. Keep it really low, though. [crosstalk] But use more probiotics. Anything else?

Evan Brand: We’re doing that tincture, I was telling you about, that’s got the uh—

Dr. Justin Marchegiani: Yeah.

Evan Brand: … I think it’s got the…

Dr. Justin Marchegiani: Yeah. [crosstalk] good one [silence]. That’s a great one. I like that.

Evan Brand: [inaudible] …worked it out. But anyhow— So, I’m sure we can do a whole podcast on that, but I figured, today, you and I should chat about creating a protocol. You know, if you’re trying to create a functional medicine toolbox for gut health, what would that look like? In that could involve things that could help with fungus, yeast, bacteria and parasites. We’ve hit on parasites and— you know, the influence of thyroid health and adrenal health. And we’ve hit on the link between parasites and leaky gut, and leaky gut and autoimmunity. So now, I feel like it’d be good for us to— you know, reveal some of the tools of the trade, which you’ve already mention one, which is the Oregano. So maybe let’s go into the order of operations first. Let’s talk about what comes first, like in this whole Functional Medicine approach. ‘Cause some people, they think probiotics are just be used anytime. And prebiotics, you can just throw them in. But really, there’s a— there’s a Science and there’s an order to herbs. Probiotics may not be the first thing that you should look at for an adult.   

Dr. Justin Marchegiani: Yeah, I know. I uh— I hundred percent agree with that. So, first things first is looking at the foods. If we have certain foods that are more offending and more inflammatory, that’s gonna potentially create the— the breeding ground on which bacteria can overgrow. There’s lots of different bacteria that can grow, so— I mean, we have more of our pathogenic type or Klebsiella, or Proteus, or Citrobacter, rella— or Morganella. These are our dysbiotic bacteria, not so good. They produce toxins in our body. They can eat up B vitamins. They can prevent our good bacteria from producing nutrition. So, of course, we want to make sure those things are under control. We will look at the foods first. Keep the inflammatory foods down. I think, potentially, in your daughter’s situation. They may have been some foods, they may have been slipping in some, like kind of pseudo-Paleo foods, potentially. [crosstalk] What food were you slipping in for her?

Evan Brand: Well, so we were doing the rice flour.

Dr. Justin Marchegiani: Rice flour? [crosstalk] Yep.

Evan Brand: Rice flour and also, there was some Tapioca starch and some of these like dried veggie snacks. They had Tapioca in there. So I’m thinking because, remember, I showed you that she had a small rash into her eye.

Dr. Justin Marchegiani: [inaudible] … improving?

Evan Brand: It’s gone.

Dr. Justin Marchegiani: And what food change did you make?

Evan Brand: The rice flour. We took it out.

Dr. Justin Marchegiani: I think there’s a gluten-sensitivity component there. So, I think [crosstalk] once you get that better, the gut bacteria will get better. So then, once that’s better, you know, looking at digestive support— so if they’re kiddos— I mean, you know, what can you do? So, typically, we’ll do like uhm— We’ll do some enzyme wafers that are really easy to chew and taste pretty good, for the little kiddos, they can eat.

Evan Brand: Is there any good brands?  ‘Cause I looked at some, and it looked like a lot of them had fructose in there, added.

Dr. Justin Marchegiani: Yeah. I mean, I like the Vitalzym’s chewables.

Evan Brand: Okay.

Dr. Justin Marchegiani: That’s a pretty good one. If they can swallow a pill, Then we’d  maybe have them do an HCL enzyme combo if they can get a pill. If they can’t, I’ll do a wafer.

Evan Brand: Ah— okay.

Dr. Justin Marchegiani: I would do that, and uhm— just really making sure they chew their food up really well. Uh— and then— you know, just cutting out the inflammatory food. So that would be my first two steps right there. And, I would even maybe do a smoothie for one meal a day and really just add some extra aminos, add some extra nutrients in there. So, it kind of gives her digestive system a break for at least one meal.

Evan Brand: That’s a genius idea. Did you know that the Vitalzym chewable has the DPP4 in there. So that would be great [crosstalk] if there is a cross-contamination issue going on.

Dr. Justin Marchegiani: Yeah. And that would be helpful. And the chewable— those taste pretty decent, too. Had a couple of kids— Yeah— fed them a couple dozen at least the last few years, do well with those. So, I like those, a lot. And then the next step is, you know, the Killing Phase. We kind of talked about, you know, the foods. We talked about enzyme support. Maybe we add them some gut-healing nutrients. Maybe we add them some collagen peptides. Maybe we add them some L-Glutamine to keep it really simple for the kiddos. Maybe we just put that in our morning shake. A couple of blueberries or berries, maybe a nice scoop of collagen or pea protein to keep it more hypoallergenic, maybe some coconut milk or MCT for some extra good fats, maybe we add some extra L-Glutamine— or like in my Lyme, we use like a GI Restore, some extra healing, soothing mucilaginous herbs, like Aloes, Slippery Elm, DGL Licorice; all very healthy and soothing. And then maybe we start the killing in a month or two later. We could start even with just like a teaspoon of Silver. Right? Twice a day, for your daughter who’s younger, right? Something very, very small. Maybe do one oil of Oregano Pearl, once a day. And over [crosstalk] Yeah.

Evan Brand: Talk more about the Silver. I mean, there’s antimicrobial benefits. I believe there’s antiparasitic benefits, possibly.

Dr. Justin Marchegiani: Yeah. I mean, Silver is proven to help with biofilms. They’re actually— My mom’s still a surgical nurse. She’s been a surgical nurse for like 45 years, and she has even— The last couple of years, they are actually adding in a Silver wrap. So, when they do like a total hip or a total knee, they’re actually wrapping the whole joint with this like Aluminum-foil-like thing, but it’s Silver. And they wrapped the joint before they closed it in that, uhm— to prevent, basically uhm— bac— antibiotic or just some bacteria coming from coming in.

Evan Brand: And that stays in?

Dr. Justin Marchegiani: No, it dissolves.

Evan Brand: Oh, it dissolves. [crosstalk] That’s cool.

Dr. Justin Marchegiani: It’s kind of like a cellophane thing that kind of dissolves. They do it— this one called Seprafilm. They put over like— you know, they do a surgery to prevent scar tissues. So, it’s similar to that. It’s kind of like a cellophane-thin kind of thing they wrap. Not sure of it’s up against the joint directly or if it’s around the fascia and the skin. I’m not sure about that. But it’s definitely enclosed around that joint for sure, to help with the biofilms and the resistant bacteria. Conventional medicine’s getting on board. And they have to, because they have a lot of problems with antibiotic-resistant bacteria. So, they kind of have to.

Evan Brand: Yeah, the C. diff, the MRSA. I’ve even heard of antifungal-resistant. Like this species of Candida diflucan and these other prescriptions aren’t working for even the yeast anymore. They’re— The yeast are evolving and getting too smart. Luckily, in our toolbox, we’re not using pharmaceuticals. We’re using herbs. And in this case, you know, if we’re talking about Candida, you mentioned the silver— We can use Silver against Candida, too. The Oregano can be against Candida. The garlic can be another good choice.

Dr. Justin Marchegiani: Yup, exactly. And there’s some liquid garlic options that we could always give her, too, as well. And then we could do some of the oil of Oregano. I like them ‘cause they’re smaller in pearl. So, like in my GI Clear 5 line, we have that, where we use the emulsified 75 percent Carvacrol extract, so it’s very potent. And it’s a pretty small uh— pearl, so typically, that’s easier to get down. And you can do that with the kiddo. You can do the Silver like I mentioned. And then we could always do some liquid garlic. So, those will be like kind of my options for kids that really had a hard time with pills, off the bat.

Evan Brand: Let’s chat about some statistics. I’ve seen kids as young as one, two, three, four years old, and they have infections, parasites, bacterial problems, a lot of Candida problems. ‘Cause the kids were unfortunately exposed to antibiotics early on, and now they’ve got a massive systemic yeast overgrowth.

Dr. Justin Marchegiani: Yeah. So, of course, anytime you have to use antibiotics. ‘Cause there may be sometimes— you know, you’re scared as a mom or dad, right? You’re like, “Oh my gosh! She’s getting out of control.” Number one, like have some things in your medicine cabinet like the Silver. You know, you could do even some ginger capsules is good, or some higher-dosed ginger tea if you can’t get that downward. It’s gonna be great. Of course, keeping the sugar out. But if we uhm— had to come at it with some probiotics during the killing, we can always add in some probiotics, some powder probiotics, and some saccharomyces boulardii. And we can put it in— in their drink, right? We can get them to have a nice little smoothie. We that in there. Or we could just mix it in, maybe their Kombucha or something. Or we could just come up with some kind of a drink they like and put it in there. That could be some really good options during the killing, and of course, we would do it after for at least one or two months.

Evan Brand: So, what do you think about Probiotics. I mean, some of the training I’ve seen and some of the protocols recommend probiotics during a killing phase and then some protocols don’t recommend probiotics. I mean, it— like—

Dr. Justin Marchegiani: It depends. There is some research showing that probiotics during antibiotic therapy can actually be beneficial. And again, most conventional antibiotic therapies don’t go longer than two weeks. So, I’m not that worried about it ‘cause we’re gonna be giving probiotics afterwards for at least two months. So, I’m not worried about if we want to go do it for two weeks. Do the probiotics while we do the antibiotics. I’m okay with it, especially if you have digestive issues. And let’s say the probiotics really helped and they’re soothing. Maybe they help keep you regular. Maybe you have a history of a lot of rebound yeast overgrowths ‘cause of post antibiotic therapy in the past, then I would. If you don’t, then I would just wait until afterwards. I don’t think you can go wrong if you do. Some people, they have histories of just antibiotics or let’s just say probiotics causing a lot of bloating and gas. And if that’s the case, and I’d probably wait. Yeah. May use some different strains. May use some coil or spore-like strains, or just doing it after the antibiotics. A lot of that flora’s gonna be knocked down. So, maybe the probiotics are more tolerable after that as well.

Evan Brand: And the same thing would apply for just straight herbs. If you were just doing straight herbal protocol. Sometimes, you’re gonna use probiotics during the killing. Sometimes, you’re not. Or you’re always using.

Dr. Justin Marchegiani: Uh— I only use probiotics during the killing, if we’re on a repeat protocol, like if we retested and we have new infections or other factions, just because I want to prevent any rebound overgrowth from happening

Evan Brand: Yeah.

Dr. Justin Marchegiani: Just kind of where you knock them out of the floor down. You even knocked the good stuff back, but we all know, if you do weeding in  the garden, you never have to go back and purposefully plant weeds, right? Weeds automatically grow.

Evan Brand: Yeah.

Dr. Justin Marchegiani: So, it’s kind of like that. We’re just kind of throwing down extra seeds during the process to take up the space that maybe those weeds would take. So, it’s kind of like a preventative thing, as well as— It can have benefits with inflammation and it can have benefits with regularity and motility as well.

Evan Brand: That’s good advise. And also, too. You and I see the Beta-glucuronidase enzyme on the Stool Test that we’re running. And if that enzyme is elevated, that could mean your recirculating your toxins and hormones and drugs and stuff like that. And one good way that we can get Beta-glucuronidase back down into normal range is probiotics. So, I love that you bring up [inaudible]—

Dr. Justin Marchegiani: Also— We can also use phages, too. Phages have some really good beneficial effects at knocking down that bacteria. And then, you know, depending on how regular you are, we can even slide in some activated charcoal, too. Some activated charcoal or some like Modified Citrus Pectin, trying to act like a little sponge and soak up a lot of the crap that are maybe sitting around your gut from all that bacteria.

Evan Brand: When would you make the call on that? Would that be like if you have a ton of bacterial infections plus parasites, they could try to treat five or six things at once? Like what if it was just H. pylori? Are you gonna hit the charcoal or not?

Dr. Justin Marchegiani: Depends on the person’s resilience. If they have a lot of fatigue, and they have a history of being more sensitive, or they have a history of lots of antibiotics and like they tell me like— you have like, in the past, antibiotics have really wiped me out, or I’m just really tired or if in fatigue, then maybe I would add in preventatively. I they’re pretty— like if energy’s pretty decent, then I would say, “Let’s wait and see.”

Evan Brand: Yep. .

Dr. Justin Marchegiani: …wait and see. But it’s something that’s always there, you know. Kind of undecked so to speak. So if we need to go, we can go to it. Of course, then one of the first things we can do is ginger tea, ‘cause ginger really helps the lymphatic systems. It’s very anti-inflammatory. Keeps things moving. It’s also a biofilm buster, too, so it helps— it actually helps the uhm— antibiotics work better. There were studies using Silver and ginger and they found that when they used the Silver and ginger, the antibiotics actually work better. So, I tell patients, if you need to use the antibiotic, use the ginger and Silver with it. And then, you can even add in the probiotics to prevent any rebound overgrowth. That way, you get the best of both worlds.

Evan Brand: Nice. That is awesome. And then, uh— I guess the last step in our toolbox— you know, we’re talking protocol, would be another test. Because, once you go through the— you talk us through the process, removing bad foods, replacing enzymes, repairing the gut…

Dr. Justin Marchegiani: Hmmn— hmmn.

Evan Brand: [inaudible] …infections re-inoculating probiotics. Then the last step in this whole protocol is the test itself. Retest and make sure [crosstalk] all the stuff we implemented was successful.

Dr. Justin Marchegiani: Hundred percent, yeah. So, if we have a specific infection we’re going after, we definitely want to put in their crosshairs, we want to aim at it. And then we want to go look to that scope again and make sure we actually hit it right. That’s kind of where that lab test retest would come in. Sometimes, if it’s just insignificant smaller amounts of yeast or smaller amounts of bacteria, and there’s not any major stuff— there’s no H. pylori, there’s no like significant bacterial overgrowth, there’s significant fungal overgrowth or any parasites, then we’ll just based it off of symptomatic relief?

Evan Brand: Yup.

Dr. Justin Marchegiani: Is there anything significant, then I want to make sure that we retest for sure.

Evan Brand: Yeah. It’s a great point. People ask it all the time. You know— “Should I retest?” “Do I really need to retest?” Maybe. But if you feel amazing, maybe we can assume. And your hair’s better, and your skin’s better, and your nails are better— like for me, I noticed when I thought my infections were gone because my weight loss stopped. Like, my weight stabilized, but I still did the retest, ‘caused I had the Giardia, Crypto, H. pylori, Pseudomonas, Candida— I had all of it. That was just too much for me to not spend the money on the retest.

Dr. Justin Marchegiani: Yeah. I wouldn’t give you the choice for those kinds of infections. But let’s say you had just a little bit of like yeast, or you had just a little bit of Citrobacter. It wasn’t off the charts and you didn’t have really awful symptoms, then I would probably say, “Hey, if you feel and improvement, that’s good.”

Evan Brand: Yeah.

Dr. Justin Marchegiani: I would say, “Let’s just keep you in the loop to retest once a year.”  

Evan Brand: So, people say, “Well, how would I know if I’m feeling good Dr. J? “ That would be things like what? If your brains working? Your…

Dr. Justin Marchegiani: Yes. [crosstalk] Everytime I— I chat with the patient, we always go over wins, challenges and corrections, diet, lifestyle, review, supplement review. So, of course, wins and challenges, what’s moving in the right direction at each appointment and what’s moving in the wrong direction. And of course, we have our baseline audit in the beginning. Patient comes in day one. Do patient exam. I got bloating. I had gas. I have diarrhea. We follow up. Make diet changes, lifestyle changes, supplement changes, how much better, what are our wins. “Oh, well. Bloating is down; 80 percent. Diarrhea is down; 90 percent.” And we continue to follow that all the way down. So each time we chat, we’re always checking in. We’re keeping our pulse on everything. I want to know exactly what we’re at, so to speak.

Evan Brand: Yep, well said. So, if those symptoms are still there, maybe the hair’s better but you still got the gas bloating. Well, could still be some yeast or bacteria going on there. Is that safe to say?

Dr. Justin Marchegiani: Yeah. And if we’re running— Let’s say, we’re running like our GI Map or our 401H and it’s looking relatively clean, then the next place we’re gonna go is the Breath Test. We’re gonna go Breath Test next ‘cause then, there may be some bacteria on there we not necessarily are picking up. And the Breath Test is kind of more of uh— a broad general spectrum because it’s looking more of the gases that bacteria is producing. So, not necessarily the bacteria, but it just tells us that there are bacteria there, producing gases if you will.

Evan Brand: How about the [crosstalk] organic acid?

Dr. Justin Marchegiani: The analogy is this, right? The analogy is this. You’re on top of the water. Is someone under the water swimming? Well, how do you know if you can’t see him? Well, you look for bubbles coming up, right? So, think of the gas that comes back on the Breath Test is like looking for bubbles on the surface trying to see if someone’s in the water.

Evan Brand: So, may I ask you this, too. What if someone’s like, “Aaaah! I don’t want to do SIBO Testing.” What about just coming in and giving some Broad Spectrum Antimicrobial Support— maybe we throw in some of the SIlver or some of the garlic?

Dr. Justin Marchegiani: Yeah. It depends. I mean, typically, when I’m recommending SIBO Testing, people are having more severe issues and the issues have been more chronic, and they’re just more motivated to get answers. So, it just depends, right? The more intense the symptoms are and the more chronic some thing’s been, people typically wanted to know what’s real. They want to be able to put their finger on it, so to speak. So I, typically, will recommend that. Uhm— if they said let’s just try it first, then I can get more to agree that, “Hey. if we didn’t get it to improve, then Round two.” “I don’t want to retest” I’ll try to get that negotiation moving.

Evan Brand: Yeah. So, long story short, you know— we try to base everything on labs cause if you don’t test, you’ve guessed. And we try to minimize guessing and checking ‘cause a lot of practitioners do that. We’re just not huge fans of guessing because you spend more money in the long run and the clinical outcome is not as good. Then that comes back on us. “Hey. Why didn’t it work?” “Well, ‘cause we’re shooting into the dark.”

Dr. Justin Marchegiani: . Well, also like. Let’s say, we come back. Let’s say, we did a Breath Test, right? And let’s say, hypothetically, the person was at a hundred for Hydrogen and 50 for Methane, okay? And then let’s say, we did a protocol. And let’s say those gases cut in half but they were still symptomatic. Well, does it kind of— Isn’t it nice to know that you had 50 percent improvement on some of those gases and that you’re moving in the right direction? Like, imagine you had a map, right? And— like Google map, right? And they only told you, you are on the right path once you got there.

Evan Brand: [laughs]

Dr. Justin Marchegiani: Well, don’t you have to want a confirmation that you’re moving in the right direction, right?

Evan Brand: Yep.

Dr. Justin Marchegiani: That’s kind of how I look at it. And the more complex and the more severe someone is, the more I like that because it gives me confidence as the doctor, that we’re doing the right stuff. But the patient is doing really well and some of the things and some of the things are really working well, then sometimes uh— I’ll let that one slide. But, I’ll let them know as a caveat that if— if we go in the wrong direction that’s gonna be our Plan B. And also I want to let people know what our Plan B is, just so they don’t think like, “Uh! Well, uhm— That’s all I got. I’m a one-trick pony,” Right? So, I want to let them know we got second options and third options, so to speak.

Evan Brand: Have you used a BioHealth? I know they’ve got a SIBO. I know they talked about a lot.

Dr. Justin Marchegiani: That’s the panel I use. I use the 900 SIBO Breath Test. .

Evan Brand: Oh, okay. That’s the best one.

Dr. Justin Marchegiani: I like it. It’s a three-hour.

Evan Brand: Okay.

Dr. Justin Marchegiani: It’s a three-hour test, and that’s nice to see the three-hour because you can get that whole window and you can see where it transitions at two hours to three, which is nice.

Evan Brand: Awesome. And then, what do you want to see on there? I mean, does that kind of like an adrenal profile where you’re gonna have a reference range?

Dr. Justin Marchegiani: Hmm— Yeah. We want to see Methane three or below, and we want to see Hydrogen 15 and below. Below 15, ideally.

Evan Brand: And— and— So, let me ask you this. If you have an overgrowth of good guys, you know, on the GI Map, sometimes, we’ll see the beneficial bacteria show up high. People always target these bad bacteria, but it— you can’t have too much of a good thing. If you have too many good guys, could that also show up and trigger those?

Dr. Justin Marchegiani: Well, if we’re running an Organic Acid Test, we would look at the lactate being elevated and if we saw that there, most people are gonna know because they’re gonna feel more bloated and gassy with probiotics. They’re gonna feel it. They’re gonna be more probiotic intolerant. So, we’re gonna know that, alright? There’s gonna be— you know, We’re gonna have specific symptoms that we’ll be able to see clinically. And then I would just be using more spore-based probiotics, instead.

Evan Brand: Okay.

Dr. Justin Marchegiani: That I’ll probably use Saccharomyces boulardii and spore-based probiotics. First is— you know, like in my line, we used like the Probioflor, which is like bifidobacteria lactobacillus. The unique thing about my Lyme is we have the Phagen. So, the phage does have some antibacterial effects and it comes from a non-dairy culture. So, a lot of people can tolerate mine. But if you’re just doing a run on the milk probiotics, and there’s no phage and— and there’s dairy in there, potentially, then there may be a problem.

Evan Brand: Yep. Yep. Well said. I think that’s it. I think we killed that one fast, but very effective. Were there any pieces to the whole protocol talk you wanted to mention?

Dr. Justin Marchegiani: I think we hit it pretty good, man. I think we’re really on the right track. Let me just see if we got any questions. I have kept my uh— question window down. I apologize for ignoring everyone.

Evan Brand: Let me see.

Dr. Justin Marchegiani: We got—  Oh, then we do now some questions. Let me see what’s going on here guys.

Evan Brand: Uh, Waled said that he hopes that we talk about Lyme disease treatment. Maybe we can do a whole podcast on that. I mean, Justin and I are continuing to learn more about the different protocols. There’s many protocols for Lyme.

Dr. Justin Marchegiani: I think a lot of people with Lyme are overtreated though. I think there’s a sequence that you have to go and work through. Like if you have a cute Lyme and you came back with uh— a bull’s eye rash, or you got any tick bite and then some symptoms follow right away, definitely go after that right away. But if it’s a chronic kind of thing, you need to get everything worked through. You need to get all your hormones work through, digestion worked through, diet and lifestyle worked through, worked through all the gut stuff, worked through the detox, and then get to the Lyme later. Uhm— so, a lot of people I find, I think, are misdiagnosed. Their immune system’s so screwed up ‘cause of other things, and then they’re seeing some Lyme come back, because, of course, everything’s gonna come back. Their immune system is down, right? It’s like, you open  your house up, and you got— you know, you come home one day, and there’s ten homeless people laying in the kitchen. Of course! Your house is wide open, right? [crosstalk] So, think of that as kind of like your gut when your immune system’s super low.

Evan Brand: Yep, well said. And, you know, the thing with the Lyme, antibiotics are very, very, very overused. And if you read some of the work that Steven Buhner’s put out. He’s got multiple books on this subject about antibiotics. Unfortunately, in many, many cases, for chronic Lyme, they just don’t work. And he’s seen a lot of people get sicker from the antibiotic. So, herbs, luckily Lyme and these other bacteria, they are still susceptible and allowed to be killed from herbs. Antibiotics— it’s not working.

Dr. Justin Marchegiani: And this is really important, too. This kind of dovetails with today’s podcast. If we do a whole bunch of killing, where does that all go? Well, it typically will and get dumped in via the hepatobiliary system and then obviously, some of the killing will happen in the gut. And then, what if our motility is not good? What if our digestion is not good? Well, it’s gonna back you up even more and you’re gonna reabsorb more of those toxins, right? So, that’s why we really want to make sure things are moving, digestion is doing good, our motility is doing good, our immune system is better. And then we have things that really help with uhm— coagulation, meaning, we’re keeping things moving. We’re not letting them— things get like static and coagulated and sticky and stuck. We want to keep it flowing.

Evan Brand: Yeah, well said. I mean, I think we may— maybe oversimplified the protocol talk, but part of that is just making sure that you’re not constipated. I mean, pretty simple, if you create all the garbage but you never take the trash out, that’s not good. You’re gonna have an overflow.

Dr. Justin Marchegiani: Totally. Totally. So, couple other questions here. Thanks Monmon for sharing the live show on your Twitter. I really appreciate it. Question for me. How old I am? I am almost 34.

Evan Brand: Nice.

Dr. Justin Marchegiani: Almost 34. Uh— Suggestions for root canals? I would uhm— do your best to try to read Ramiel Nagel’s book. I would do oil pulling and I would do your best to try to avoid it. See natural doctor. If you have to get it, get a full extraction. There is new research or new therapies coming [crosstalk] Stem cell therapy as well. I posted a video on my YouTube and my Facebook channel about it today. Take a look at that, justinhealth.com— I should say, facebook.com/justinhealthwellnessclinic, or click on the the facebook link. I don’t know what the topic is. I came in late. Okay— So, Pheochromocytoma. I think that’s a tumor on the kidney that produces excess aldosterone. I’m going back to like doctorate school physiology class. I think that’s the aldosterone-producing tumor. So, I mean, all the stuff we would do for cancer: Ketogenic diet, uhm— toxicity, coffee enemes, crucumin— all of that. I’ll let you hit the rest of them. Go ahead.

Evan Brand: Yeah. Let’s see what else we’ve got. Uh— Tessa. Wanting to know about starting Iodine, what to do to get started. Uh— Dr. Korosin talks about Iodine a lot in the aspect that many people are doing it, but if they have thyroid antibodies, it’s making the situation worse. So my advice would be get your thyroid panel run. Look for the antibodies first ‘cause you could if you have [incomprehensible], you could make yourself worse if you go start pumping a bunch of Iodine. And uh— Korosin’s got a bunch of literature he link’s, too about that conversation.

Dr. Justin Marchegiani: Keep the Selenium in there, two to four hundred micrograms. And once you’re stable, if you want to play around with some Iodine, hundred and fifty micrograms to start at one drop or one hun— 150 microgram dose, you know, per week, installing increase. They just make sure the B vitamins, the vitamin C, the Selenium, the Magnesium, and the Zinc are all in with it. And also, stay tuned for my Thyroid Reset Plan book that will be coming out in the next six months.

Evan Brand: Oooh!

Dr. Justin Marchegiani: It’s [inaudible] … draft for the first half of the book, just the other day, so I’m really excited about it.

Evan Brand: Congratulations.

Dr. Justin Marchegiani: Yeah. Thank you.

Evan Brand: Alright. Let’s keep going. Uh— Home remedies for flu and what to eat everyday to avoid s—

Dr. Justin Marchegiani: Uh— Remedy. Last week’s podcast. We did a whole podcast on it. Also I did a whole blog post: “What to do when you get sick” Part 1, Part 2. Part 1’s on the diet and lifestyle. Part 2 is in the supplements. So, that answers your questions right there.

Evan Brand: Man, Justin is killing it today. All great. Another question. Is it necessary to take HPA Access Support during a Kill Phase if you’re in Stage 1 or 2? I would say, it depends on your constitution. I think Justin would agree and…

Dr. Justin Marchegiani: Yup.

Evan Brand: … depends on your sleep, your stress level, how many hours are you working, how much rest are you getting. Are you working or are you off from working? What’s your circadian rhythm look like? Are you travelling? What’s going on? Like, what’s in that stress bucket?

Dr. Justin Marchegiani: I would say yes. It’s always gonna be good. And then depending on how much stress would be what we’d— what specific herbs we would recommend.

Evan Brand: Oh, we take adaptogens everyday, so we’re gonna say yes always.

Dr. Justin Marchegiani: Yes. I got some Ashwagandha here. So today, I’m crushing the Ashwagandha Supreme, right here. Absolutely. I’m gonna hit two right up now. I love it. It helps with my mood. It helps with sleep. It helps with energy. I find two. I can take it before bed if I— I get like disturbed or like stressed out, because— I don’t know. I watch the news or uhm— just something happens. Like, I just got some project. I got to do some deadline. Taking that really helps kind of curtail the Cortisol rush at night, along with uhm— some GABA and Magnesium, too.

Evan Brand: Yeah. I’ve been hitting Ashwagandha, the Reishi, the Motherwort, the Ziziphus, Albizia, the GABA, Chewable PharmaGABAs. I love them. Those were all good choices. “Hello, Dr. J and Evan. How much probiotics  are appropriate for a two-year old after antibiotic treatment for Bronchitis. If you’re looking into those infant strains that we’re using, some of the infant probiotics, typically— if we’re talking powders, it ends up being about…

Dr. Justin Marchegiani: Quarter teaspoon, right?

Evan Brand: … about quarter to a half teaspoon per day…

Dr. Justin Marchegiani: Yup.

Evan Brand: … for my daughter. We’re doing that currently. And she’s a little less than two years old but we just put it into her drink of water, and she just sips on it all day.

Dr. Justin Marchegiani: Yeah, and then for us, like my son Aden, I’m just like basically tipping my finger a little bit and some— Like I dump some probiotics on like the uhm— the container, and I’ll just kind of slip my finger and I’ll just touch it. And then I’ll apply it to his gums. Or like, we’ll put it on my wife’s breast, where like my child will feed from and just apply it there. And then, when he feeds, he gets the probiotics that way. So, you can do either way, if [crosstalk] they’re still not doing solids.

Evan Brand: That’s a good idea.

Dr. Justin Marchegiani: The infant’s strain’s great. That’s really what you want, I think, up to age four. [pauses] Yeah, up to age four, like that’s when you want to be just doing the infant’s strains.

Evan Brand: Uh— Tessa gave us some more follow-up about the Iodine question. She does not have a thyroid and has grave disease. Would that change your—

Dr. Justin Marchegiani: So, Dr. Wright has a protocol for graves where he does really a high amount of Iodine to basically overload the Iodine symport system, and then downregulate uhm- hormone Iodine or let’s just say thyroid hormone production. There’s that protocol. What’s out there? Dr. Wright’s— Jonathan Wright’s Protocol. I personally— and again, you need to be working with the clinician with this. Graves, it’s really serious. I mean, all of these conditions, I don’t recommend just doing Dr. Google. Like, we’re giving a lot of good information, which is great. But you really want to be working with someone in applying it. But for hypothyroid graves, we’re doing L-Carnitine, we’re doing Melissa and Lemon Balm, okay? Blue Flag— We’re also gonna be doing Lithium Orotate. Okay. And of course, an autoimmune Paleo type of template. I did multiple patients over two hands full that I had taken them out of grave-like states, so to speak.

Evan Brand: What’s the Lithium doing?

Dr. Justin Marchegiani: Well, Lithium has an effect on modulating the thyroid hormones.

Evan Brand: Oh, wow! That’s cool.

Dr. Justin Marchegiani:  Yeah. Lithium Orotate, we— I typically just uh— a formula used with the combination of Melissa or Lemon Balm and Blue Flag, and a couple of other herbs in there that are really helpful. The Carnitine, the Lithium; that’s gonna be great. And of course, you know, we added some Selenium, too, to help with the antibodies.

Evan Brand: Nice. Nice. Great. Great follow-up there. Very— Very good. Uh— does oil pulling really help? Yeah. It does. We’ve used uh— oil pulling ourselves. Both of us have, but there’s some— there’s some cool things you can do with it too. And there’s actually some testing you can do to look for all these different infections, like Hidden Cavitation infections. In the oil pulling, there’s some cool literature on like Silver and coconut, and all that, helping with like oral bad guys.

Dr. Justin Marchegiani: Absolutely. Vitamin K, too, is gonna be excellent for root canal stuff. Of course, collagen. Your teeth’s gonna be— have protein as well. So, good collagen peptides is gonna be excellent as well.

Evan Brand: Uh— last question here from Roslyn. “My SIBO test results are Methane 60+, Hydrogen 20; probiotics do not agree with me.

Dr. Justin Marchegiani: Yeah. Imagine, Roslyn. Are you also constipated, too? Can chime in there? Methane— typically, he put in a Methane diameter and a more constipated Hydrogen, dominate more diarrhea. You’re still positive on the Hydrogen, too. So you may have a— you may also alternate with the two. So, if you can Chime in there fast and let us know what your motility is like, I can answer you more specifically.

Evan Brand: Yeah. And we’ve used that ___[30:51] Formula. It’s got some of the Quebracho extract in there, which can help drop Methane.

Dr. Justin Marchegiani: Quebracho. [crosstalk] Love it.

Evan Brand: Quebracho. Sounds like a part here something. I don’t know.

Dr. Justin Marchegiani: I love it. It’s great.

Evan Brand: Like if— If Roslyn doesn’t get back to us, then we’ll just assume that if Probiotics are not agreeing and Methane’s that high.

Dr. Justin Marchegiani: So, of course, you know, if let’s say she is more constipated, then we would do things like ginger and natural prokinetics to keep things moving. We use ginger tea. Uh— maybe some of the Iberogast formula to keep things moving. Another support I used, called MotilPro, which is excellent. And then, we work on knocking down that bacteria. We probably hold off some of the probiotics if it makes it worse. But we’d make sure things are moving. Maybe even some uhm— Magnesium citrate to keep things moving too.

Evan Brand: Yep. Good advice. Vitamin C, too. You could pump by, what? Two to five grams or so. Vitamins C. That should be enough to move the bowels.

Dr. Justin Marchegiani: Probably a little higher than that, but yeah. I mean, I think, two maybe a little light, but definitely five to eight, five to nine will probably move it for sure.

Evan Brand: Okay, cool. Uhm— more more question here. Why can’t my eyes handle bright light? It could be due to the adrenals.

Dr. Justin Marchegiani: Adrenals, yup. Hundred percent.

Evan Brand: Typically, weak uh— weak adrenals, so definitely get your adrenals tested and looked at some of the adaptogens to help handle bright light. Like the people, you know, especially the women who come out of the grocery store. The first thing they do is pop down those sunglasses on and they just can’t live without them. That tells me adrenal problems.

Dr. Justin Marchegiani: Yeah. I agree. Hundred percent. Alright, cool. I think we answered almost everything. Would spore probiotics Just Thrive be enough to repopulate to the  gut after the Kill phase or should you rotate the— I would rotate other strains. I’m not familiar with Just Thrive. I’m a big fan of MegaSporeBiotic. We have it on our site, justinhealth.com/shop, under Gut Section. We’ll put the links in the Show Notes. I like that one. There are a couple of others that are out there that are really good. I know uhm— Primal Defense by Garden of Life is a decent one. I like the MegaSpore, though.

Evan Brand: Yep. Cool.

Dr. Justin Marchegiani: And then, Sue says, “My—” ‘Kay. So, I don’t know. Yeah, so that’s about the Pheocytochroma. Not sure if you have. That’s a tumor. So, you’d really want to get that uhm— resolved there with your doctor. But you’ve got to go on  like anti-cancer protocol for that. Uhm— hope that helped guys. Any other questions, comments, or concerns, Evan?

Evan Brand: I think that’s it for today. If people want to reach out. Schedule a consult with you. Check out Justin’s site, justinhealth.com. You can book a consult with him. If you like to book a consult with me, either of us, we’re happy to help you. You can just check us out; evanbrand.com is me. And make sure you subscribe to the YouTube channel here. We’re what? Thirty three plus thousand so— [crosstalk] Let’s get Justin up to fifty grand, you guys. and then a hundred, and then a million. So, subscribe, subscribe, subscribe, and share, because sharing is caring. And Education is the first step to greatness. How can you approach this stuff if you have no clue. You can’t. You got to learn, and then you can apply.

Dr. Justin Marchegiani: Absolutely. And just so everyone know, if you’re listening to us on YouTube. You know, we have the conversation and the video kind of going back and forth, so you can see our ugly mugs. But we also have the podcast link, and we are recording our podcast in super high audio quality. So, if you want to upgrade the audio, feel free and subscribe to our podcast channels. Again, we’ll have them in the show notes if you listen to Evan or I. We have the upgraded audio for you and that’s only been the last month or so. So, we’re really trying to up our game, guys. We want to make sure you get the best information at the highest quality on your fingertips.

Evan Brand: Yeah, so that’s on iTunes. So, look up Justin Marchegiani, or just type in Beyond Wellness on your iTunes or podcast app. And you can subscribe there. Cool thing I’ll tell about, Justin, iTunes just released a Podcast Analytic so now we can check and see our people actually paying full attention for the full episode or is everybody stopped listening after 20 minutes. Now we can see the drop-offs. That’s pretty neat. And then, for my show, it— just type in my name, Evan Brand, and you’ll find it.

Dr. Justin Marchegiani: Absolutely. I think if you go to evanbrand.com, there’ll be a link for your podcast. If you go to justinhealth.com or beyondwellnessradio.com, there’ll be a link there for the podcast. Click it. It will bring you to the button where you can subscribe. And then, we’ll make sure you get updates as soon as you can. And then also, if you’re listening on YouTube, smash the bell. YouTube’s doing some funny things you’re not gonna get the notifications if you are subscribed. So, hit subscribed and then smash the bell right next to it. That way, you’ll get all the notifications. And we’re gonna try to continue dropping lots of knowledge bombs. Let us know. Give us some comments below the channel if you’re listening on YouTube about this. We want to hear some of your concerns. We’re gonna work on responding on them a little more. And also, we want to get more feedback on what you guys want to talk about. So, let us know. We really want to engage you and bring more information. You know, our goal is to help, you know, ten million people. So, you know, we’re doing in the thousands range right now. We want to help more. So, allow us to help you by figuring out what your needs are and let us help you fulfill it, okay?

Evan Brand: Amen. We’ll see you guys after Christmas. So, I hope it’s good for everyone.

Dr. Justin Marchegiani: Yeah. Merry Christmas to everyone. Happy holidays, too. And hope you guys have a happy healthy New Year. And check out our hacking the holidays podcast. Lots of good solutions there so you guys can kick butt, stay healthy and not get sick throughout the holidays.

Evan Brand: Amen, brother.

Dr. Justin Marchegiani: Hey, Evan. great chat with you, man. You take care and Merry Christmas.

Evan Brand: Take care. Merry Christmas. See you.

Dr. Justin Marchegiani: Take care. Bye now.

Evan Brand: See yah.




Jonathan Wright’s Protocol by Dr. Jonathan Wright

Steven Harrod Buhner

Health Benefits Of Potassium

Health Benefits Of Potassium

Health Benefits Of Potassium

By: Dr. Justin Marchegiani

Introduction to Potassium

Over the years we can see a major change in our food habits. While our ancestors were mainly dependent upon fresh fruits and vegetables, but in recent days most of us get inclined to choose ready-to-cook food items or easy to make food items to balance either fast or a sedentary lifestyle. This change of food habits may be a prime reason for inviting several non-communicable diseases like hypertension, cardiovascular disease, arthritis, osteoporosis, repetitive kidney stone formation etc. Fresh fruits, vegetables, and nuts are very good sources of Potassium.

Potassium is a well-known mineral that plays several vital roles in our body. Primarily, maintaining the fluid and electrolyte balance, maintaining the pH of the body fluids (the acidity or alkalinity of the body fluids depends upon pH), assisting in nerve signaling transportation to muscle tissues and uphold normal functioning.  According to the World Health Organization (WHO) recommendations, the adults should take at least 90 mmol (3510 mg) potassium every day. [1] However, recommendation for daily intake of potassium may vary country-wise; as in the United States, Canada, Bulgaria, and Republic of Korea recommends 120 mmol of potassium every day. [2] Hence, it is imperative to have a detailed knowledge about the role of potassium in our body.

Normal potassium level in blood

The normal limit of potassium is 3.6 to 5.2 mmol per liter of blood. An immediate medical attention may be required if you have lower than 2.5 mmol of potassium per liter of blood. Hypokalemia is the medical term to indicate a low level of potassium in the body. 

Symptoms of low level of potassium

Symptoms of low Level Potassium

The following are some symptoms associated with low potassium level:

  • Fatigue
  • Numbness
  • Palpitation
  • Abdominal cramp
  • Nausea and Vomiting
  • Constipation
  • Excessive sweating
  • Low blood pressure
  • Fainting
  • Depression
  • Confusion

If you frequently face any of the above symptoms then it is always advisable to go for a health checkup. 

Health Benefits of Potassium

Health Benefits of Potassium

Apart from the above conditions which may be controlled by maintaining a proper potassium level in the body, it also imparts various health benefits which can inspire you to maintain a healthy potassium level.

Controlling hypertension

Hypertension is a common health problem; almost one-third of Americans have hypertension. Hypertension usually does not provide any symptoms, but it is one of the major cause of stroke and cardiovascular diseases and kidney problems. Sufficient potassium intake can effectively control hypertension. An intake of less amount of potassium-containing diet can result in excretion of less amount of potassium through urine. This indicates electrolyte imbalance (imbalance of sodium-potassium ratio in the blood), which causes hypertension.  An adequate amount of potassium intake can maintain electrolyte balance and influence receptors, hormones and nervous system to dilate or expand blood vessels. Dilation of blood vessels reduces the extra pressure exerted by the blood in the wall and control hypertension.

Prevent stroke and other cardiovascular diseases

Research study provides the evidence that if you have potassium deficiency due to inadequate poor potassium diet, then your urine will definitely contain less amount of potassium. This will lead to over functioning of the heart and can cause a stroke because of increase blood pressure lowering effect. The potassium-rich fresh fruits and vegetables are also an adequate source of antioxidant. These antioxidants prevent cardiovascular diseases by scavenging or removing free radicals. 

Improve bone health

Osteoporosis is another most common condition, especially in women population. It is a disease which occurs when the bones in our body become weak and may break very easily (maybe from a fall or, maybe even due to sneezing in case of serious disease condition). The potassium therapy is a cost-effective treatment to improve your bone health and prevent osteoporosis. Potassium-containing diet is alkaline in nature and assists to maintain the pH of the blood and prevents bone tissue damage.

Calcium, the most important bone content can also be restored by consuming potassium-rich diet because potassium can decrease the calcium excretion through urine. A research study showed that 90mmol/day of potassium can able to decrease the parathyroid hormone activity and thus it prevents calcium loss from the bones. 

Prevent kidney stone formation

Pain due to kidney stones is unbearable; often causes problems during urination, like burning sensation, bladder discomfort and also induces or creates urinary tract infections. Potassium-containing diet is a simple remedy to the individual who suffers from repetitive kidney stone formation problems. Potassium reduces absorption of calcium in the gut wall. Potassium can do this, as it reduces phosphate retention by the kidneys. Human studies conducted in the U.S.A. showed that a potassium-rich diet can able to reduce the repeated incidence of kidney stone formation in both men and women. 

Low Potassium level negative for diabetic patient

Diabetes is a metabolic disorder. American Diabetes Association revealed that almost 15.7 million Americans are suffering from diabetes. Several human research reports stated that lower potassium level aggravates the diabetic complications by increasing BMI, and increasing waist size, while the fasting insulin level also gets increased. [6]

Sources of Potassium

Sources of Potassium

There are several easily available potassium-rich food sources are present in nature, which can easily increase the potassium level to combat potassium deficiency. If you opt for a suitable dietary measure, then it will be very economical and can save money to buy different potassium supplements.

Most interestingly, a calorie-rich diet contains more potassium. The below table mentions rank wise different dietary sources of potassium and their calorie value:

Dietary source or name of the Food Serving size (gm) Quantity of Potassium (mg) Present Energy (kcal)
Baked potato with flesh and skin A small sized potato (143) 738 128
Canned Prune Juice One cup (256) 707 182
Canned Carrot Juice One cup (236) 689 94
Tomato (paste) Quarter cup (65.5) 664 54
Cooked Green Beans Half cup (74.5) 654 19
Canned White Beans Half cup (90) 595 149
Canned Tomato Juice One Cup (243) 556 41
No fat and low fat containing Plain Yogurt Eight ounces (245) 531-579 127-132
Tomato Puree Half Cup (125) 549 48
Skinned Baked Sweet Potato One medium size (119) 542 103
Fresh Orange Juice One Cup (248) 496 112
Cooked yellowfin, Tuna Three ounces (57) 484 118
Banana One medium size (118) 422 105
Skimmed Milk One Cup (245) 382 83
Boiled parsnip Half Cup (80.5) 296 55
Boiled Green Peas Half Cup (82.5) 217 37
Boiled sweet yellow colored Corn Half Cup (79) 162 72
Boiled Cauliflower Half Cup (70) 89 14



  1. http://www.bmj.com/content/346/bmj.f1378
  2. https://www.mayoclinic.org/symptoms/low-potassium/basics/definition/sym-20050632
  3. https://www.webmd.boots.com/a-to-z-guides/low-potassium-hypokalaemia
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650509/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963920/

The Cholesterol Myth

Cholesterol Myth

The Cholesterol Myth

By Dr. Justin Marchegiani

If you’ve only been told what the general public has been told about cholesterol and heart health, you probably believe cholesterol is one of the prime culprits behind heart disease. But do we have enough scientific support to prove this statement, or it is just another health myth that’s been blindly taken for true?

According to the WHO (World Health Organization), almost 20 million cardiovascular deaths occurred in 2015, making them responsible for about 30% of the global death rate. It is obvious that we need to take extra care to ensure the health of our hearts, but it is also our responsibility to properly investigate medical and dietary recommendations. The objective of this article is to guide you through this process and to help you understand the role cholesterol plays in keeping us healthy. After reading this article, you will have the knowledge to decide for yourself whether or not you want to restrict dietary cholesterol!

Introduction to Cholesterol

There is a much controversy among researchers who have been investigating cholesterol as a contributory factor towards heart diseases. Cholesterol actually has many beneficial roles, and there is insufficient evidence to support claims that high cholesterol is correlated to death due to cardiovascular issues.

  • There is cholesterol present in all fatty foods.
  • Cholesterol is necessary.
  • Dietary intake of cholesterol has negligible effect on plasma cholesterol level; as the liver eliminates excess cholesterol and maintain health plasma cholesterol level
  • Restricted diet and lifestyle measure cannot control hypercholesterolemia occurs due to hereditary or genetic reason.
  • Hypercholesterolemia can occur at any age, even children can also develop due to liver dysfunction.
  • Cholesterol consumed through food is unable to dissolve in blood.
  • Lipoproteins, comprised of lipid and protein molecules, act as a carrier in cholesterol transportation in the blood circulation.They are classified into two main groups: low density lipoproteins (LDL) and high density lipoproteins (HDL). LDL can be large and fluffy (and safe), or small and dense (and dangerous).
  • Large LDL particles are not harmful and do not play any part in plaque formation.
  • A case for saturated fat: Butter is more heart-healthy than margarine, as margarine creates small, dense LDL, whereas the saturated fat in butter converts the small, dense LDL into the large, fluffy (safe) LDL. Let the butter flow!

Click here to work with a functional medicine doctor to discover your cholesterol levels!

Cholesterol-Rich Diet: Dangerous or Not?

This is an important question to ask. The British Medical Journal (BMJ) conducted research which showed that lowering cholesterol levels by switching to a cholesterol-free diet could not reduce the cardiac diseases related death rate.

Dietary guidelines promote vegetable oil over saturated fat, and this is reflected in national spendings on vegetable oils. However, dietary saturated fat has been shown to reduce the chance of heart attacks, whereas vegetable oil may actually increase this risk. Other factors that may cause increased cholesterol levels in the blood include:

  • Family history, as this affects your genes and predisposition to certain genetic patterns.
  • Your lifestyle: stress levels and diet have a profound affect on not only your general health, but also on your gastrointestinal function.
  • In instances of leaky gut syndrome, gut permeability allows food particles and toxins to leak into the bloodstream, which leads to elevated cholesterol and triggers inflammation.

The Vital Nature of Cholesterol

Cholesterol is one of the primary constituents of cell membranes and plays a major role in the maintenance of normal human cellular physiology. Cholesterol takes part in protein interaction and in signaling systems inside the body. Steroid hormones and bile acid are actually composed of cholesterol!

Research conducted in the 1960s reported cholesterol has no impact in the formation of atherosclerotic plaque. When the British Heart Foundation showed their skepticism, scientists in New York re-evaluated these findings by using new technology. This more advanced technology turned up the same results: increased cholesterol levels, specifically LDL-cholesterol, does not cause plaque progression. This is made obvious due to the fact that cholesterol lowering drugs are unable to lower the risk of death for patients who take these drugs. What’s more, according to the BMJ Open journal publication, almost 92% individuals with high cholesterol level have longer life span!

A Case For Dietary Cholesterol

A Case For Dietary Cholesterol

In 1960, the American Heart Association guidelines made the recommendation to stop eating eggs due to their high saturated fat content. This started the dietary trend of restricting egg consumption in an attempt to be heart-healthy. However, research conducted by Harvard involving more than 80,000 female nurses showed that eating eggs daily does not increase the risk of cardiac disease. It’s important to keep an open mind, seeking out evidence-based research rather than blindly trusting paid-for promotional gimmicks. The “fear” of eggs is starting to reverse, as a recent dietary recommendation published by U.S. Dietary Guidelines reported that egg yolks is an important source of protein. A good step forward!

A survey conducted in South Carolina also support a saturated-animal-fat rich diet, which includes foods such as meat, eggs, whole milk, butter, cheese, and bacon, as their research proved there is no correlation between blood cholesterol levels and dietary fat intake ratio.

The Lancet publications are one of the world’s oldest and best known general medical journals. One Lancet publication stated that 74% of plaque formation in the arteries is associated with unsaturated fat sources, including canola oil. Attempting to reduce your risk of cardiovascular issues by cutting natural sources of saturated fat (like butter) is not where our focus should be, as this study proves that unsaturated fats are the real culprit destroying our health.

Drugs to Lower Cholesterol: More Dangerous than Cholesterol Itself?

Statin drugs are one of the established pharmaceutical brand medications for lowering cholesterol levels to “reduce the risk of heart disease.” Statin drugs are frequently prescribed to patients at risk for cardiovascular problems, but their effectiveness is not proven, and the list of side effects is long.

Continuous intake of statin drugs can cause fatigue since energy production become reduced. These medications increase the risk of blood clogging up the arteries (atherosclerosis) and heart failure by decreasing vitamin K2 absorption. Side effects also include diabetes, cancer, musculoskeletal disorders, neurodegenerative disease, and cataracts.

The effectiveness of statin medications preventing heart attacks or death from heart attacks is negligible, as multiple studies have revealed that statin therapy can only produce a 0.6% risk reduction of having a heart attack when compared to rates of patients who did not take statin drugs.

How to Reduce Your Risk of Heart Disease

How To Reduce Risk Of Heart Disease

So we see that not only do statin drugs not protect against cardiovascular disease, they also come with a long list of dangerous side effects. So what can you do to lower your risk? Here are some tips to live a healthy life:

  • Replace simple carbohydrates with complex carbohydrates (whole grains) and fibers: Refined grains, such as white bread, pasta, flour, and white rice are high in glucose. Glucose is a simple carbohydrate with a high glycemic index, which can lead to insulin resistance. Increased insulin can also convert fat into trans fat, which causes inflammation and is associated with blocked arteries, cardiac disease, and cancer.
  • Cut the sugar! Sugar leads to all sorts of illnesses, including an increased risk of heart disease. Start by ditching the soda (one can has over twice the recommended daily maximum amount of sugar), and from there continue to make healthier swaps.
  • Be active! Take part in a sport, go for a job, lift some weights, swim, dance… Exercise lowers the risk of heart disease and boosts your mood!
  • You’re better off swapping the canola oil for coconut oil (a healthy source of saturated fat)!

Click here for a professional health consultation and start feeling better today!











How Sugar Feeds Illness

 How Sugar Feeds Illness

How Sugar Feeds Illness

By Dr. Justin Marchegiani

America takes first place… as the top consumer of dietary sugar in the world. Our sugar consumption is a major player behind the skyrocketing rates of chronic diseases like diabetes, obesity, and cancer. The average American now consumes an average of 130 grams of sugar per dayfor reference, the daily recommendation for women is a maximum of 20 grams a day! This is more than just sad: it’s dangerous. Today we are going to outline some of the effects of sugar on our immediate and long-term health.

What is Sugar?

What is Sugar

This might seem obvious, but food producers are getting craftier with their labeling as they realize more and more people are making the choice to eat healthier. Sugar goes by many names, with new ones popping up all the time. Some sugars are natural, most are processed, and more and more are being created in labs. Here are just a few names to look out for on product labels:

  • Agave
  • Brown sugar
  • Corn sweetener
  • Corn syrup
  • Fruit juice concentrates
  • High fructose corn syrup
  • Honey (raw, pasteurized)
  • Invert sugar
  • Malt sugar
  • Molasses
  • Raw sugar
  • Sugar
  • Sugar molecules ending in “-ose” (dextrose, fructose, glucose, lactose, maltose, sucrose)
  • Syrup

Click here to consult with a functional medicine doctor and discuss underlying health issues preventing you from living your best life!

What About Fruit?

Yes, fruit technically contains sugar, in the form of fructose. However, there is a big difference between enjoying a piece of fruit as an after-dinner treat, versus having orange juice with breakfast and fruit juices as your beverage of choice throughout the day. Studies have shown that eating fruit whole can lower risk of developing type 2 diabetes, drinking fruit actually increases your risk! The fiber you get from eating fruit whole slows the absorption of the sugar and keeps the glycemic index low. Plus, it takes a lot more squeezed fruit to fill a glass than you could possibly eat in a serving, meaning you’re consuming way more sugar than you realize!

The Effects of Sugar

The Effects Of Sugar

Consuming large quantities of sugar has been linked to an increased risk of a variety of chronic diseases including obesity, cardiovascular disease, diabetes and non-alcoholic fatty liver disease (NAFLD) as well as cognitive decline and even some cancers!

There are also many health issues caused by sugar that aren’t as talked about:

Sugar depletes the body of critical electrolytes, antioxidants, and minerals, which leads to cell death, muscle spasms, insulin resistance, and other health defects. Its effects on the immune system leave you prone to getting sick more often and more severely.

Sugar feeds bacteria and parasites, like yeast and Candida. It also depletes the body of good gut bacteria, promoting Leaky Gut and other gut infections. Chronic pain, vision problems, and even wrinkles can be worsened by sugar!

Sugar causes chronic inflammation in the body, and inflammation is said to be the root cause of almost all disease.

How Sugar Feeds Cancer

Sugar consumption has been proved to feed cancer cells and speed up the growth of tumors. Too much sugar consumption causes insulin resistance, as well as a specific protein to be released from your pancreas. This protein causes your cells to replicate and become immortal, which is how pre-cancerous cells can begin to take over.

Cancer cells prefer glucose over oxygen, but our mitochondria can’t use the glucose as energy. White blood cells are our immune system’s soldiers, and need vitamin C to function properly. A cancer patient needs lots of healthy white blood cells to fight the disease, however, sugar blocks the absorption of vitamin C in our bloodstream, weakening our immune system.

In summary, sugar causes cancer cells to reproduce and thrive, and blocks the mechanisms that would slow down or kill cancer cells and tumors.


Sugar addiction runs deep, and can be hard to kick. Stay tuned for Dr. J’s thoughts on artificial sweeteners, approaches to beating sugar addiction, and healthy alternatives for sugar.

Click here to talk to a functional medicine doctor about staying healthy this holiday season!

Top Anti-Aging Foods

Top Anti Aging Foods

By Dr. Justin Marchegiani

Everyone ages, the question, therefore, is not will you age, but how will you age? Will you suffer from chronic pain and inflammation, develop diseases such as dementia, diabetes, and cancer, lose your mental capacities or your ability to walk and run? Or will you remain in good health with good posture, retain a great state of mind and mental clarity, keep balanced hormones and healthy relationships?

The truth is, the choice is yours, and it is exactly that: a choice. If you are determined to live a long life with your body and energy at their fullest potential, you can do so! However, there are no magic creams or pills that will prevent you from showing signs of aging. The secret to aging gracefully and successfully lies in a series of healthy diet and lifestyle choices which we will outline below.

What is Aging?

What is Aging?

Disease, dementia, cancer, loose saggy skin, slowed brain function, slow and weakened body: these are NOT predetermined signs of aging! These are the consequences of the Standard American diet (SAD) and lifestyle that have been normalized by our society. Recent discoveries have shown that inflammation, the shortening of your telomeres, and  mitochondrial deterioration are what control the aging process.

Click here to schedule a consult with a functional medicine doctor to determine your personal causes of inflammation and illness!

What Causes Aging?

What causes aging?

Inflammation causes the diseases and health decline that are hallmark symptoms of aging, which can eventually lead to autoimmune disease and cancer. This can be combated by finding the root cause of inflammation (commonly diet-related) and taking steps to prevent it.

Telomeres sit at the end of our DNA, and their length is related to our biological age (different from our chronological age, which counts birthdays, your biological age is how old your body is in relationship to your health). Telomeres are shortened by unhealthy habits such as smoking, and eating inflammatory foods.

Our mitochondria produce 95% of our energy, in the form of ATP, but the byproduct of the energy production is harmful free radicals which cause damage to the mitochondria. Science has shown certain foods, as well as the enzyme CoQ10, to be powerful in defending against free radical damage.

How to Age Successfully

How to age successfully

We are able to curtail disease, wrinkles, and a general decline in health through taking proper care of our bodies. A big part of preventing disease and deterioration as you age is dependent on your diet. The following foods are just some of the many healthy options we have that are full of the nutrients and minerals vital for good health and longevity:

Bright colored fruits and veggies provide beta-carotene and vitamin A, which protect against cellular damage and premature aging. They are also great for your skin and eyes, meaning less wrinkles and better vision. These include: bell peppers, carrots, sweet potato, and broccoli.

Leafy greens, such as spinach, collard greens, lettuce, and kale, contain several top antioxidants. Lutein and zeaxanthin have been shown to reduce the risk of cataracts and macular degeneration. Beta-carotene, vitamin C, and sulforaphane are cancer-fighting antioxidants present in leafy greens. The folate in spinach improves your short-term memory and might even lower the risk of developing heart disease and cancer. Vitamin K1 is found in collard and salad greens, which is linked to vascular health, strong bones, prevention of heart disease and Alzheimer’s disease, and can treat certain cancers.

Eggs also contain lutein and zeaxanthin, making them an unexpected friend of your eyes. They are a natural source of vitamin D, as well as choline, which protects your brain, nervous system, and heart. Be sure to buy organic, pastured eggs for all the benefits they have to offer!

Blueberries are chock-full of antioxidant power. By fighting oxidative stress, blueberries can help neutralize the damage caused by free radicals. They help reduce the risk of cancer, heart disease, stroke, and arthritis while boosting your vision and immune system!

Citrus contains vitamin C, which helps your body produce collagen. Collagen is responsible for healthy joints as well as tight, healthy skin. The quercetin in citrus has anti-aging properties and also helps fight inflammation.



You are what you eat, so if your goal is to be healthy and thriving in old age, the food choices you make today need to be healthy ones. Luckily, these foods are not only dense in important nutrients, they are also delicious!

Click here for a consultation with a functional medicine doctor and a personalized health plan!






Fibromyalgia Natural Solutions – Dr. J Live Podcast #159

Dr. Justin Marchegiani and Evan Brand discuss about Fibromyalgia including its cause and symptoms. Learn how some of the symptoms connected to it such as anxiety, depression, IBS, memory problems are also seen in other health conditions.

Listen as they talk about some of the viruses, infections, gut health, heavy metals, thyroid and adrenal imbalances as possible contributing factors or underlying issues leading to unfavorable health symptoms. Gain some valuable information regarding natural solutions and lifestyle changes that you can do to combat these symptoms.

 Natural Solutions for Fibromyalgia

In this episode, we cover:


02:15   Fibromyalgia Symptoms

03:48   Viruses and Infections

07:20   Gut Health

10:31   Adrenal Issues

13:19   Heavy Metals


Just In Health iTunes

Just In Health YouTube

Dr. Justin Marchegiani: It’s Dr. J here in the house. Evan, how we doing today? Happy Monday!

Evan Brand: Hey, man!  Happy Monday to you. Life is good.

Dr. Justin Marchegiani: Yeah. We had a little technical difficulty here. But we are rolling. The show must go on. So, any any updates for me here that you want to bring to my attention before we dig in and get dirty?

Evan Brand: Well, I’m just excited. I’m excited to talk with you about fibromyalgia. This is one of those things in that category like IBS where the conventional doctors—

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand:.. give people diagnosis and then they just end up with drugs in their pockets and they don’t have any real success. And people struggle for years and years and years, they end up with these other symptoms that come along with fibromyalgia like anxiety or depression or IBS. And once again, conventional Docs, they just don’t really have a high success rate with this issue.

Dr. Justin Marchegiani: A hundred percent agree. And fibromyalgia is one of these interesting types of diagnoses. Basically you have to have uh—central allodynia pain, which is kind of like this uh— pain that may be true like 11 different random spots of the body. So they look for these different pain, tender spots, shoulders, chest, hips, back. And they are looking for like at least 11 out of the 17 or so spots. And if you have it, great, you have fibromyalgia, right? Coz basically what is a central allodynia? That means your nervous system is so hypersensitive that it’s dectecting, you know, you rubbing like this, just things that shouldn’t cause pain. It’s sensing that it’s pain. And that’s the biggest issue coz  the nervous system is so upregulated, it’s like having an antenna that’s so hypersensitive that it’s picking up stations uhm— that shouldn’t be picking up.  And it’s the same kinda thing. Your nervous system is an antenna that’s picking up all these nociception or pain sensation where it shouldn’t be. So we want to get to the root cause of why that is. Go ahead.

Evan Brand: Yeah. There is uh—conventional drug that a lot of people end up on. The Lyrica, which I’m sure you’ve heard of.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: Huge pricing commercials for it. And I’ve had people taking that and they just don’t notice much and then sometimes the side effects, maybe not without drug, buy any of the drugs, can be worse than the actual thing that you’re trying to fix into the first place. So that’s just— it’s scary because when you want to get a root cause answered, you’re not gonna get it unless you start running some of these functional medicine testing that we’re talking about. So I just have a list of symptoms I wanted to read that could come along with the fibromyalgia. So that could be anxiety, that could be concentration and memory problems, depression, fatigue, headaches, irritable bowel syndrome. Now, that sounds like a lot of other things that we need to talk about.

Dr. Justin Marchegiani: Exactly. And here’s the thing, right? A lot of people may have gluten sensitivity or hypothyroidism or heavy metal issues or gut microbial imbalances, the issue is that some people may manifest with Hashimoto’s. Some may manifest with fibromyalgia symptoms who have a lot of the central allodynia pain. So it is interesting because some people, they can have the exact same core underlying issue, but have a totally different diagnosis. And all of diagnoses is a constellation of symptoms that are typically put into one category, right? The chronic pain symptoms—that’s gonna be in the fibromyalgia category. Memory symptoms—that’s gonna be in the category. Fatigue symptoms— that could be in the thyroid or adrenal category. Gut issues— depending on where that inflammation is located, that could be in the Crohn’s or Ulcerative Colitis or there’s no inflammation in the tissues that can be in the IBS category like you. So this is where it’s tough because all conventional medicine is tyring to categorize known symptoms in the categories call the “disease”. We are trying to trace it upstream. And the hard part about functional medicine is certain people can have the exact same imbalances and manifest with totally separate diseases. That’s the hardest part people to wrap their heads around.

Evan Brand: Yeah. Let’s go into the viruses. My wife when she had joint pain several years ago, you said, “Evan, the first thing you need to look into is going to be some of the viruses.” And so we got a blood test run on her. She did not show up with Lyme, fortunately, but she did show up with the cytomegalovirus and then also the mycoplasma. Can— so can you speak about those a bit? And how that could be causing joint pain that could get misdiagnosed?

Dr. Justin Marchegiani: A hundred percent. So there are certain infections like mycoplasma is one of them they can manifest in the joint tissue, for sure. So that’s one of those conditions that an infection can really be driving a lot of that joint pain. And we know certain infections and certain imbalances can manifest with certain symptoms. Like we know that hypothyroid issues, low thyroid function can manifest having low thyroid hormone in joint pain. We also know like infections like mycoplasma can also cause or call  the lower thyroid function and then potentially manifest in joint pain. We also know it could potentially manifest in the joints and you know certain antibiotics like Minocycline to help knock it out. We prefer to use some of the herbs coz it tends to be safer on the gut microbiome in the long run, number one. And then with your wife symptoms, we notice that she already had a pretty good diet.  And there was a tick bite involved in your wife’s last issues. Is that correct?

Evan Brand: That’s right.

Dr. Justin Marchegiani: And so because of that, you know, we were leaning towards, “Hey, let’s just to after the infection and see what happens.” And when we knocked out the infection, everything got a lot better. So that was good to see that.

Evan Brand: Yeah. It was so— it was so it was so easy, too. So simple. Just modify the immune system, all of a sudden things are better. So, if you have fibromyalgia or you have joint pain and general pain stiffness, you gotta make sure you roll those in. So go to your doctor if you’ve got a natural path or functional medicine practitioner, that’s even better. Try to get them to test you for the Lyme, plus the co-infection. So coz like I said she had a negative result for Lyme, but she was positive for these other things, Cytomegalo and the Mycoplasma. So you gotta go look for them.

Dr. Justin Marchegiani: Hundred percent. So, again, any issue any like disease issue, like if you’re someone and we’re focusing on fibromyalgia today because that’s got a certain bit of symptoms that manifest in pain. So if you resonate with that, great. This is going to help you. If you don’t resonate with fibromyalgia symptoms, but you have something else, this podcast is still gonna be helpful because we always trace it back to the underlying imbalances, which can manifest itself in different symptoms. But one thing that’s gonna be uniform across the board is looking at the gut. The gut is really important coz that’s where a lot of your immune system is. 70 to 80% that’s where your body digests and breaks down nutrients, that’s where uhm—your— essentially you digest and break down all the food you’re eating. So if we’ve a bottleneck in the breakdown of our nutrition, we’ve a bottleneck in how our immune system functions, if we have a leaky gut and your immune system’s being overreactive, or if we have an infection there, that can create a lot of underlying stress that may manifest itself in different symptoms. And again, kinda linking it back to fibromyalgia, if you have these chronic pain issues, those 11 kind of places a central allodynia pain to touch, right? Your diagnosed 11 places of pain on your body, at least. And you have the fibromyalgia, the diagnosis, then we definitely have to rule out the gut. And again, here’s a thing that really throws people for a loop is that you can have gut issues and not have gut symptoms – that’s the really hard thing. You may not have the bloating, the gas, the diarrhea, the constipation, the acid reflux, and you may still have a gut issue.

Evan Brand: Uh-hmm. H. pylori we see it every week in the clinic. So if you’ve got H.Pylori, you’ve got that bacterial infection, that’s suppressing HCl production, therefore you’re not digesting your food. So if you’re seen floating stools or you’re seeing undigested food particles in your stool, that could all be adding up to this whole picture of the depression, the anxiety, the fatigue. Maybe even skin issues, too. So maybe you don’t have the fibromyalgia diagnoses, but you’ve got fatigue, depression, anxiety maybe some sleep problems maybe some skin issues. That could all be tied into leaky gut— that intestinal permeability. It could be something as simple as H. pylori or like Dr. Justin Marchegianientioned, it could be H. pylori plus Mycoplasma plus maybe some bacterial overgrowth like the SIBO case or plus parasites, which is something we often talk about, plus fungus. You know, typically it’s not just one thing. Most of the time, by the time people get to us, they’ve been suffering for quite a long time and therefore, there’s usually a handful of things that we’ve got to address. Now on the thyroid, is the pain going away just a side effect of you fixing your thyroid? Like all the sudden thyroid function improves and the pain just goes away. Could it be that simple if that were your biggest root cause?

Dr. Justin Marchegiani: Well 100%. So you can see it quite frequently that just getting someone on some T3, some thyroid hormone can really help because they may be on thyroid hormone, T4, but they’re not able to convert and activate it. So there’s TSH, right? The pituitary hormone that most conventional docs measure to look at thyroid function may look nice and pretty but they’re not making that conversion from T4 to T3. So their T3 levels may be low, and if you come in there with some activated T3, you may start to put some of their thyroid symptoms on remission. Now, we have to understand, from a functional medicine perspective, what’s palliative and what’s root cause. So we have to make sure we actually fix the underlying conversion issues, if it’s nutrient or if it’s inflammationm if it’s gut, if it’s immune. And we also had to fix the underlying nutrient absorption issues, the infections, the autoimmunity, right? So whatever those issues are. So, we kinda understand that there are certain natural medicine things we can do. There are palliative, which are great. And there are certain things like, I think you mentioned earlier about the uhm—your child has a little bit of eczema and you know, putting a little bit of coconut oil in there helps. But you recognize, that’s palliative not root cause. So we try to get to the underlying foods that may be causing it.  Same thing in this analogy with thyroid. And thyroid, low thyroid hormone can express itself in about 70 different symptoms—hair loss, fatigue, uhm— brain fog, anxiety, right? All these different symptoms. Also, the pain symptom is one of the.

Evan Brand: Yup. Well said. And if it’s Hashimoto’s, if it’s an autoimmune thyroid condition, that T3 could help symptoms improve. In this case, you could get more energy, could help reduce pain. But if you haven’t stop that autoimmune attack by addressing infection, supporting the adrenal glands, making sure the diet is dialled in, and you don’t have any foods that are creating antibodies against the thyroid. You know, those are some of the big three needlemovers you got to have on board to fix this thing at the root and not just be stuck on T4 or T3 or combination for the rest your life.

Dr. Justin Marchegiani: Hundred percent. So we also know that adrenal issues— adrenal imbalance is not necessarily adrenal fatigue, of course, you know, most people in the conventional medical world will hear adrenal fatigue and think adrenal failure like Addison’s disease, okay? Which is valid but we also know that there can be imbalances in cortisol that may not be a full disease failure kind of situation. It may be just lower adrenal cortisol issues, lower DHEA because of HPA axis dysfunction. And if that’s the case, we want to make sure we support that because adrenal, zero adrenal glands produce cortisol, which is your natural anti-inflammatory hormone. And again, people that have chronic pain issues, a lot of times, we put on like COX 2 inhibitors, things like that. Severe pain, of course, Opioids is an Oxycontin, which is a another big issue in itself. But also, Prednisone and Corticosteroid drugs that basically have the ability to knock down inflammation, the problem is, why aren’t your own glands working enough to cover up that inflammation, too? So, if we get the adrenals working better, we can kinda make some of our own homemade Prednisone on our own—our own homemade Corticosteroids to help cut that inflammation down.

Evan Brand: So talk about what happens. Let’s say somebody is on the steroids long-term, that’s also going to affect the adrenals as we’ve seen on some lab results.

Dr. Justin Marchegiani: Yeah. It will throw off some of the feedback loop, so will disrupt the HPA axis, that’s the brain talking to the adrenals. That’s that nice feedback loop or that kind of internal thermostat that our body has. So we do have that there that we have to work on because that can affect that thermostat. Uhm—number two, it can really throw off your blood sugar. So taking a lot of synthetic steroids that when we create protocols for a patient, we may use small amounts of precursor hormones like Pregnenolone or DHEA. And these are gonna throw things off in the same way that a drug would. Because these drugs are very, very powerful. They can mess up the feedback loops. But if you’re using a corticosteroid, it can really mess up your blood sugar and in the long run, it can even create osteoporotic situations. It can really thin out the bones. It can really weaken the gut lining because these steroids break things down,right? They’re anti-inflammatory but they are also very catabolic. So it’s great in the short run, right? When we get back on track, but not good in the long run coz it can really mess up our glandular physiology. How that—how our hormonal systems work. And the feedback loops that kinda keep them connected.

Evan Brand: I think it’s worth mentioning heavy metals, too. I don’t think it’s good to be

necessarily the number one cause for most people, but we notice that if there is a gut issue, let’s say somebody does have these gut bugs, they could have a detox problems, too. Just coz their body, their liver is just so overburden. Let’s talk about metals a bit. So could be just amalgam fillings or could be occupational exposure or could be too much of a lower quality or too big of a fish like a tuna that’s causing issues. Let’s talk about that for a minute.

Dr. Justin Marchegiani: 100%. So we can definitely have toxicity issues like Mercury which can be very inflammatory. Mercury also is similar to the halide group so it could fit into the receptor site where Iodine would typically bind in. Fluoride and bromine can also pinch-hit there as well. So that can create a lot of issues regarding that. Mercury can also jam up the mitochondria. I mean feel free and go to PubMed and just type in “Mercury and mitochondrial function” and you’ll see increase in heavy metals can decrease mitochondrial function. And again, as—as glycolysis and our Krebs cycle turns and we have betaoxidation on the flipside, we generate about 36 ATP’s per pump and those ATP’s work is kind of the cellular currency for energy, right? It’s how our body kind of you know, creates energy and you know, has aerobic metabolism to create ATP, which is our body functions and that’s kinda the byproduct of having a healthy metabolism.

But if we go in there and all these gears are moving spitting out all these ATP, which is basically cellular energy, and we messed that up, we throw kind of a monkey wrench into the gearbox, that’s gonna prevent optimal ATP function, which is gonna throw off our energy and our body ability—our body’s ability to function, right? Lower energy is gonna create symptoms. Anytime you have lower energy, you  tend to start having brain fog issues, mood issues, fatigue issues, pain issues, sleep issues because energy is the byproduct of a healthy metabolism. So when energy goes, metabolism is going down. And when that’s starts to go, other symptoms tend to manifest as well.

Evan Brand: Yeah. I’ve gotta say two things. One is glyphosate. If you’re not 100% organic, make your goal to be a 100% organic as close as you possibly can. I love that people are honest. I had a guy who on his intake form, I asked the question, “What percentage or diet is organic?” He said 0%. I’m like, “Man, you’re getting glyphosate.” We can measure it. We can prove it on a piece paper, but just know if something is not labeled organic, especially your fruits and veggies, assume it’s contaminated with glyphosate. Just like Justin mentioned about Mercury, antibiotics, glyphosate. Those are all mitochondrial killers and so there’s nothing worse that you could possibly do than have glyphosate in your system. Now, fortunately, you can detox it by using the sauna. There’s other methods that we talked about but just make it a goal. Throw out the—you know, go donate or throw out the non-organic stuff. Swap it out. Pay the extra buck. Pay the extra 2 bucks. It’s gonna be much, much more valuable in the long-term and much cheaper in the long term because you’re gonna prevent yourself from having health issues associated with glyphosate toxicity.

Dr. Justin Marchegiani: Hundred percent. Hundred percent. I had a conversation with someone recently that say, “Hey, you you realize organic food doesn’t have any more nutrients than conventional food.” And I said back to them,”Well, it depends.” There are some studies that do say organic food does have more nutrients. I mean there are some people that say that’s there are some studies by Temple University that shows a much higher level in nutrition with organic food than conventional food. I just think it depends on what kind of organic we’re talking about factory farm, you know, big corporations have started labeling things organic. And again, are they gonna have the same high level as a local farm regarding fertilization, you know, rotating the crops. I mean, if you just have an organic farm without pesticides, but you just continue to heat that crop season after season, don’t let it rest, don’t switch spots, and don’t you know, add synergy to the land, right? Some synergy is like, for instance, when the cows pass on their— basically have their manure, their bowel movements, you’re bringing the chickens afterwards to kind of help uh knock out all the grubs, right? Which prevents other animals from coming in. So you can add synergy to the land that helps, number one, increase uhm— fertility to the soil, right? Increases that top soil. But number two, it helps other past and creatures from growing, which can create havoc down the line. And so, in other words, uhmm—some people can really hit that soil hard and decrease the nutrient densities of the organic food. It has less nutrients, anyway. But anyway, so let’s just pretend this person is right. They told me organic food has the same nutrition as conventional food. Alright. Fine. We do know the research is quite conclusive that organic food has less pesticide residue. Of course, coz to be organic, you can’t have pesticides on it. So just the fact that— let’s the nutrient’s density is the same from organic food. While I’m definitely not getting the pesticide exposure, which Evan mentioned earlier with Glyphosate or Roundup. It’s so important. coz there are so many studies on that coming out that it’s very toxic on the body, on the liver, on the gut. And essentially many other places.

Evan Brand: You know, the European Union, they’re successfully banning it. I’ve been trying to keep up with this is much as I can. It looks like glyphosate is seeing the end of the rope in the European Union. I hope something is to follow in the US, but I just don’t think it’s gonna be anytime soon here.

Dr. Justin Marchegiani: I agree.

Evan Brand: One of the thing I wanted to mention is on the CDC’s website about fibromyalgia, they say that much much much higher rates of ankylosing spondylitis occur with fibromyalgia and Justin and I mentioned this on a mini podcast. That’s an autoimmune condition. And so it sounds like what they’re saying without saying it because maybe they’re not noticing the link, is that this whole thing is likely just a autoimmune issue. The IBS, like you mentioned, the Crohn’s or the Colitis, the Hashimoto’s, like this could all just be autoimmunity at the root. And we’ve just got to go through all of our causes and fix the autoimmune issue and then all of a sudden you can reverse the symptoms.

Dr. Justin Marchegiani: Hundred percent. And again, there’s like over a 180 autoimmune conditions. So my analogy is anytime you have a physical chemical or emotional stress, or  you know, imagine having this fancy pearl necklace, every time you put tight, that’s a physical chemical or emotional stressor in your life. And let’s just say every little spot where that pearl connects to the necklace, they’re not all the same strength. There maybe some part to that chain that are little bit weaker. Think of that as genetic predisposition at work. You’re gonna have certain genetic links in the chain that are going to be a little bit weaker. Now what does that mean to you, as that stress comes on, that part of the chain may be more likely to break than another part. Let’s say  Pearl 33 is more likely to break them Pearl three or Pearl four, right? Now, Pearl 33 may be ankylosing spondylitis. And that stressor may be Roundup or could be Hashimoto’s or let’s say Pearl 4 is Hashimoto’s for someone else, right? So think of every little link in that chain as a different disease that could manifest if that link is broken. And where that link you for you, is gonna be based on your genetic predisposition. What we have control over is not pulling that damn chain type. Let it go. Let it relax, right? How do we do that? All of the diet and lifestyle things. Just cutting the Round up out. Eating organic. That pulls the stress off. And getting that good sleep, having good thoughts, fixing your gut, fixing infections, making sure you can digest and break down all that really good food that you’re eating. Get your hormones under control if there’s imbalances there. Does that make sense, Evan?

Evan Brand: Oh, it sure does. I mean, just like you picture a big wall think of like a submarine. You’ve got a 1000 switches in all these red switches are flipped on. We’re just gonna go down the list and just flip all those red switches off, and all of a sudden you turn off, you’ve not pulled the trigger. You’ve got the loaded gun, but we’re just gonna decide not to pull the trigger. People think that like genetic testing is the end-all be-all and “Oh, my gosh! I’m genetically predisposed to X.” It’s like that doesn’t change the protocol at all. That just means you need to be even more diligent. If your family had a history of this condition or other conditions, you just have to be more diligent. That doesn’t mean you’re toast. That doesn’t mean you’re definitely going to get XYZ disease or condition. That just mean you got pay attention. You’ve gotta make sure you’ve got all the pieces going in your favor.

Dr. Justin Marchegiani: Yeah. And I pretty much work with the genetic stuff. I don’t get so hyper fixated on it. I just assume the worst for everyone. And that way, we’re making the changes in hydration, with sleep, with water, with toxicity, with gut. We’re not gonna give synthetic folic acid. We’re gonna give super high quality methylated B vitamins. We’re just making that assumption for everyone because I can’t be hurt by making that assumption in that direction. If I make it the opposite direction and say, “Hey, it’s okay. You probably don’t have a folate issue. I’m gonna save some money and put some crappy synthetic folic acid in my multivitamin instead of high-quality activated folate. Then I can go wrong, right? I may save a little bit of money but because we’re interfacing with our patients daily and weekly, we know that we’re better off rolling the dice in favor of there being an issue with that. So we always have the higher quality nutrients in there to cover our butts.

Evan Brand: Yeah. And I had a a woman who emailed me this morning she said, “Evan, I had a reaction to gluten. Do you think it’s time that I go get tested for celiac?” And I told her, “It’s better cheaper and likely safer just to assume that you’ve got a massive allergy to gluten,” Then you just need to stay way because really, going to the gastroenterology process where they make you eat— what is it two slices of bread for like a week or two and then they cut out a piece of your intestine to try to see if all those cilia where destroyed or flattened. And then a lot of times, there’s even false negatives there. So you could do all that work. Destroy your body, create inflammation and then say, “Oh, it says negative.” It’s like just stay away and be more diligent. Don’t tell people that it’s a preference. Just tell it—  tell people at a restaurant it’s a gluten allergy. Make  they change their gloves. And you’re gonna be much safer as opposed to waiting for that diagnosis. So that’s kinda what my message is. If you have these symptoms, maybe  you’re not been officially diagnosed with fibromyalgia, but you’ve got these symptoms, you’ve got pain and the sleep and fatigue. Just go ahead and think, “Okay, maybe I’ve got XYZ but now I’ve just gotta start working on all these big pieces we talked about.

Dr. Justin Marchegiani: Hundred percent. Yeah. Makes a lot of sense. And someone’s chiming in here on the YouTube live here, chat saying that uhm—their local farmer told him it’s certified organic, allows them to spray toxic pesticides two times a year. Not sure what kind of certification that is.  Typically, the USDA certification’s pretty good. The fied has to be—the land has to be for three years without pesticides to even get that certification. So I’m not sure if we’re talking about the same USDA certification, number one. And a lot of farmers they’ll use other compounds that tend to be a little less toxic to help with spring. So like for instance we have our property done which had to use probiotic spray and we tend to use essential oils. And again, there may be chemicals in there, of course, but they may be harmonious and have less toxic burden. I’m more worried about the toxicity of the pesticides. And let’s say you bought an organic food that was, you know, in one of these farms that was spray twice a year,  well, isn’t that gonna be better than a farm that’s sprayed weekly?

Evan Brand: Right.

Dr. Justin Marchegiani: So I’m kinda like good-better-best. Hey, if I’m gonna cheat or if I have a choice option between something that was spray weekly versus twice a year, I’m still gonna go with twice a year because that toxicity burns is gonna be good. Also, we can just utilize the Clean 15 and the dirty dozen. Great, if we’re gonna buy a food that’s conventional or somewhat conventional with pesticides. Let’s look at the Clean 15 and see the foods that have less pesticide residue and avoid the dirty dozen and/or just get a really good uhm— vegetable or fruit wash that you can wash off some of the external pesticides at least.

Evan Brand: Yeah. And some of the regulations under the USDA, there’s a difference between 100% organic and just certified organic. So, obviously, the best thing to do which is contact a local farmer, which is what I do. I buy some bison meat and other products locally. And I know that they don’t ever use chemicals ever and if they do have to use chemicals, they’ll tell you. And they’ll say, why, what happened how much, what did they actually use. So if you just look up local harvest and go look up type in your ZIP Code, your location, go find some local people and just talk with them. That way, you  don’t have to guess anymore whether something’s actually legit from the grocery store. I still go to the grocery, but I try to source other things outside where I can check the person’s hand. It’s just a lot more viable experience that way.

Dr. Justin Marchegiani: Yeah. And again, we just have to do your best, right? Sometimes we don’t have the best options you know, when we’re traveling or we’re going out to eat. But if we can control the 80 to 90% when we’re home and we’re in our house and the foods that we choose in our area, that’s gonna be the most important thing. Also, when you’re healthy, you get a little bit more wiggle room; when you’re chronically sick, you don’t. So if you’re chronically sick, then you really got to be careful and make the best decision possible and uhm— if you’re not, then 10 to 20%, I’m totally okay with. And if you’re going to get exposed to things, activated charcoal is a great option uhm— taking some extra detox support may be helpful, too. So all that’s really good if you know you’re gonna be getting exposed to not so good things.

Evan Brand: Yeah. Take in your enzymes, too. Take in your acids, your enzymes. You and I both use enzymes that are gonna contain special ones that helps. So if you do get  to it. exposed to gluten, that can help reduce the flareup. If you are sensitive, you are react to it.

Dr. Justin Marchegiani: Exactly. And then James here, talks about uhm— his fatigue still lingers daily, can’t shake it. Thyroid tested good with me, uhm—Modafinil works great and gets me to the day. And Modafinil or Provigil aspirin is a big fan of it. Not a huge fan long term. I mean I think it’s not fixing any of the underlying issues. So the diet helps I mean I would look more at the adrenals, I’d look more at the mitochondria. I forget your specific case, James, I know you’re doing good for a while. So if you just had a backward slide recently, we’d wanna chat and figure out what underlying stressors have creeped up or make sure the infections are gone, or make sure the mitochondria are functioning as optimal as possible. So I wanna look a little bit deeper. I’m fine, though, using Modafinil Provigil punctuated time frames, you know, a work deadline comes up, major stressors you know, you have to induce some extra stuff on the weekend with your family or work stuff, then fine. Take that to really upregulate your body but just keep in mind there’s something deeper we got a look at. And just  you know, things like sleep and things like hydration and people forget those all the time.

Evan Brand: Yup. Very simple but sometimes the most simple stuff moves the needle.

Dr. Justin Marchegiani: Yeah. I mean Daniel talks about here, uh— talks about what can cause jellylike lumps in the semen sometimes painful to pass. Well first off, I would do like a urine analysis first, just to make sure there’s nothing, no UTI your uhm—you know, nothing that’s kidney or bladder base. Make sure there’s no infections in the piping, so to speak. Uh—again, I would also rule out epididymitis. Make sure there’s no infections in the epididymis. There could be a bacterial issue that’s just causing these uh— the semen to kinda agglutinate or stick together. And also, even just run a sperm analysis. Just to make sure this— the semen are actually alive and it’s not a whole bunch of dead semen uh— in there as well. So, I would look there first. If the diet’s good, if everything else is good, I would just make sure any type of infections and that urinary area are also clear too. E. coli, those kinda things.

Evan Brand: Awesome. Well, we gotta wrap up. Both of us gotta get back to our calls, but we hope you guys enjoy the show and leave us questions. You can leave us questions in the future. So if you didn’t catch this live, go to Justin’s YouTube channel. Go on his video, write in your questions, we’ll try to answer as many as we can or will save those for future show. And then same thing for topics. If you have topics that you want us to address, please put them on there. And if we need to reach out for a consult, check out Justin’s site. It’s Justinhealth.com You can schedule a consult. If you wanna schedule a consult with me, check out my site EvanBrand.com and we are happy and willing to help you. So please reach out if you’re suffering around the world, just phone in and Skype consults make it easy for us to help you.

Dr. Justin Marchegiani: And check us out on our podcast channels, too. We’re trying to do our videos here on YouTube, but we’re also trying to record everything in higher-quality audio. So, if you want to hear  us in some higher quality audio, check out our podcast channels. Again, if you go to Evan’s site, EvanBrand.com or my site, Justinhealth.com click on the podcast and you can subscribe to get updated, audio as well. Anything else you wanted to add, Evan?

Evan Brand: I think that’s it. Awesome and Ross, yeah, Mastic Gum is great for H. Pylori.  Awesome show today, Evan. Great as always. Appreciate your energy and your insights and let’s chat real soon.

Evan Brand: Likewise, man. Take care.

Dr. Justin Marchegiani: Take Care. Bye now.

Evan Brand: See you.








Hacking the Holidays – Dr. J Live Podcast #160

Dr. Justin Marchegiani discusses different options, substitutions and modifications that can be made during the holiday season. Learn about what ingredients to use in some of the traditional Thanksgiving dishes including the turkey, stuffing and gravy that can help to still improve your health. 

Gain insight on the different modifications and options that you can use for some of your desserts so you can still indulge without having to feel guilty afterwards. Also, learn about some other cool options including meal timing, fasting, exercise and alcohol intake for a healthier you during this holiday season.Healthy Holiday Recipes

In this episode, we cover:

01:49   Grain-free holiday meal

03:01   Enzyme Support

05:55   Desserts Options

10:36   Timing Recommendations and Alcohol

15:00   Exercise



Dr. Justin Marchegiani:  Hey, everyone! It’s Dr. J here.  Evan, Happy Holidays, man! We got a short Thanksgiving Day week. I love turkey day, man. Some time with the family, really good eating. Are you excited too?

Evan Brand: I am and I’ve got blue skies here which is very unusual for this time of year. We’ve got sunny every single day this week. So I’m super grateful for that.

Dr. Justin Marchegiani: Love it. Yeah, it’s a great time of the year. It’s uh— important year, time of the year to be really grateful and to be extra uh— particular in all the things that we have to be thankful for. Coz there’s a lot of things but it’s easy to be so focused on everything it’s not there. So we got to really focus on all the things that are there. So couple that is just how about, just some really good Intel that we can use to hack our holidays. Meaning we can still indulge in feel good and connect with our family members but not go into a food coma and feel like absolute crap. What do you think about that?

Evan Brand: Agreed. Yeah. A lot of our clients recommend we do this subject because they feel deprived if they’re doing AIP or some type of dietary approach. They feel like that we’re the bad guys and we’re making their holidays not as fun. But that doesn’t have to be the case.

Dr. Justin Marchegiani: Absolutely. So, couple of things if you look at Thanksgiving, it can totally be Paleo, right? We have like basically the centerpiece in the Thanksgiving Day meal is the turkey, right? Awesome. Especially if we can go after the darker meat. That’s gonna be excellent. Good fats, right? Try to buy an organic or at least a Pasteur-fed turkey. It costs a little bit more but the nutrients are to be much higher, right? So you get good fats and proteins there. That’s the kind of a starting point. And then after that, you control your sides. So most people want mashed potatoes and maybe squash which you know, I’m okay doing a little bit more starch in the holidays. I’m okay with that.  It’s better than doing, let’s say a grain-based stuffing, that’s number one. Number two, we try to substitute for the things that we typically have grains. What’s gonna have grains? Well, typically, your gravy is gonna be thickened with flour so we do a gravy that’s gonna be a carrot and celery based and we thicken it with coconut flour if we do it. And we use the actual uhm— turkey stock from the actual turkeys. That’s a huge way to get to the stuffing, I mean the gravy going. And then the stuffing there’s typically some good stuffing recipes out there where we do a celery and carrot-based stuffing and it’s totally grain-free and it taste phenomenal. So, off the bat, you can have your starches. I’m okay with that. Number two, you have the gravy. Because the gravy kinda goes on everything. So if your gravy isn’t too good, you can really mess everything up coz you just basically coating everything with thickened uh—turkey giblets and flour. And then uhm—then after that, you have I mentioned your starches and then after that you can do cranberry sauce, really, you know, super Paleo. You can do like, I’ll do green beans and I’ll cut up some bacon, I’ll layer that on there, too. Uhm—those are kinda my big things off the bat and of course, a really good turkey. We’re gonna smoke our turkey this year. We typically use our smoker this time of the year. Any other thoughts, Evan, off the bat for your? Just with the Thanksgiving Day meal?

Evan Brand: Well, my thoughts are you got me hungry but besides that—<laughs>

Dr. Justin Marchegiani: <laughs>

Evan Brand: But besides that, the enzyme piece.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: You and want to talk about enzyme.

Dr. Justin Marchegiani: Yes.

Evan Brand: So let’s go into that. So one’s that you and I were talking about off-air was one from designs for health. It’s called allerGzyme. And this is more specific to people that if they’re just going to go off the rails, they are going to do or get it possibly get exposed maybe a cross-reactive issue with dairy or egg or soy or gluten or casein peanuts, things like that. You can take the specific enzymes. They’ve got like a patented version they call it what, Glutalytic in there.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: It is supposed to be pretty helpful. And they’ve got bromelain. Way but it’s a very, very super high dose bromelain which is a pineapple enzyme. It’s a really good enzyme. So there’s that. And then you and I both have our own custom digestive enzyme formulas that I say those are the best nutritional insurance policies that you can bring with you like a little glass jar or something.

Dr. Justin Marchegiani: Especially the fact that people forget that I uhm— having a meal like that is gonna be stressful not necessarily because it’s bad because obviously we’re gonna try to make the substitutes. We’re not gonna focus on eliminating. We’re gonna focus on substituting.  So we have the most healthiest options possible but because we’re probably gonna eat such a ton of food, it’s going to be a lot for our digestive system to handle. So we’re gonna really utilize more enzymes and more HCl and maybe even some bile salts to really optimize our ability to actually break it down.

Evan Brand: Yeah. I love it. I’ve got a small little old honey jar that my wife just keeps in her personnel and so if we go out to restaurant or if we got to family member, I’m just gonna pull out those enzymes and popp them down. So that’s can be my strategy and I think everybody who is dealing with bloating, gas, indigestion, a lot of these common symptoms heartburn, you’ve got that excessive heaviness feeling.

Dr. Justin Marchegiani: If you already got those symptoms and it’s not even Thanksgiving yet, then you’re a person who needs extra care when it comes to using enzymes.

Dr. Justin Marchegiani: Absolutely. So we talked about the meal. We talked about maybe the potatoes and/or the sweet potatoes or the squash. I’ll typically put some extra cinnamon on my squash, too, which is great for blood sugar. And the blood sugar and the insulin kina receptor sites that which is good. I talked about the green beans. I talked about how to maximize the gravy because the gravy is one of those things that’s gonna be layered on everything. So if you can fix the gravy component— and we’ll have in the show notes some Paleo uhm— gravy recipes so we’ll make sure we get some Paleo recipes in the notes.  Uh—we’ll make sure we get some stuffing recipes. Coz those are gonna be the the big— the big things—the gravy and the stuffing. Almost everything else, you can dial it in. The turkey’s pretty good. You can do really good cranberry sauce, you can do uhm— squash, you can do sweet potatoes, you can do regular potatoes or any other sides that we’re missing.

Evan Brand: Yeah. You hit the green beans.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Sometimes peas, sometimes carrots you.

Dr. Justin Marchegiani: Yup.

Evan Brand: I think honestly, if you’re eating real food and you just always think, “Am I eating real food?” you’re gonna be just fine.

Dr. Justin Marchegiani: Yeah. Then a couple of things—let’s go to desserts pretty fast. So we’re just kinda laying out the meal options or the meal substitutes, I should say, and then we’ll talk about little hacks that you can incorporate, too. So, off the, my Paleo Apple Crisp is something that I utilize a lot. I actually have it made once a week and it’s basically just a combination of the crust, which is gonna be coconut shreds, pecans and walnuts, kinda crushed up. And it’s gonna be kinda layered over some Granny Smith apples that are cut up. And the Granny Smith apples are basically mixed with butter. And they’re also gonna have a little bit of cinnamon on them and then we also have a little bit—

Evan Brand: I need this.

Dr. Justin Marchegiani: .. a little bit of organic palm cane sugar. And we like the organic palm cane coconut sugar because it’s got a glycemic index of 15. So it goes into your bloodstream a little bit slower and we try to use the least amount possible. So what I recommend is put the smallest amount whether it’s like uhm an eight of a cup or something in there. And just kinda glaze it and then mix it up. And then try a couple before you know, layer all the nuts and cook it. And then just see if it’s at the sweetness you want. So I don’t need a lot. I just put a very, very small amount. Once I have it, you know, typically, an eighth of the cup or sixteenth of a cup, a very—typically, I just glaze it. I don’t even h measure it. I just gently glaze it over so very small amount. And then once I have it to taste, then I pretty much put uhm—then it’s mixed with butter, of course, right? And then I put that topping right on top and there and then 350 for 30 to 45 minutes till the apples are nice and soft. And then you’re pretty much good to go.

Evan Brand: That sounds delicious. Did you invent that recipe or is that something you found?

Dr. Justin Marchegiani: No, I invented that one. That’s a good one. And then if you want mix it up, too, you want to make it more like a cake, you can do uhm—a tapioca and arrowroot flower and then typically you just add the arrowroot flour in with the apples, typically, half a cup to cup each. And then that kind of gives that more of a thickened flavor. And then you can just bake it not use the nuts. And then it comes more like a cake. And that’s a really good option. We have that Apple cake option on there, too. So, apple cake and/or uhm— the Paleo Apple Crisp. Apple crisp I think is a little bit more healthy coz you don’t’ have any flours in there. They’re all just a good healthy nuts and fats.

Evan Brand: Right. Yeah. I have a female client last week. She said she’s going to make a like a pumpkin pie but she’s going to do coconut flour and I think she said coconut flour and Coke and cashews maybe. So I know that there’s options out there. I just don’t eat too much dessert anyway, you know, besides a good piece of chocolate. But if you’re somebody who you’re going to go to one of these events and you think, “You know what I don’t want to miss out” Well then you just make it. You know, let  everybody else bring the meat and veggies. You just bring a healthy dessert. That way, you know that you’re gonna be safe and you’re not gonna cause yourself a flare-up or new problems.

Dr. Justin Marchegiani: Totally. For the most part, your turkey’s gonna be good, right? If you’re gonna do your mashed potatoes, fine. If you do cranberry sauce, if you’re gonna do squash, if you’re gonna do green beans or will do like uhm— Brussels sprouts with bacon, that’s typically gonna be good. You’re gonna mess it up with the excess uhm—gravy. So do the gravy right way and you do a healthy stuffing options. So I recommend is if you’re going somewhere, maybe you bring some gravy, or if you don’t bring the gravy, maybe you just uhm— bring the stuffing. And people won’t even know. We bring some of these healthy Paleo options we go places to get invited. People wouldn’t even know the difference a lot of times.

Evan Brand: Exactly.

Dr. Justin Marchegiani: The big thing is for me it’s about, it’s not about, “Oh, Dr. J, you’re being, you know, such uh—so tight about this. You know, why can’t you roll?” Well, the reason why  is I wanna feel freaking good afterwards.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Yeah. I wanna eat a lot and I want to feel good. And there are great options and I don’t notice a difference in flavor. I can make my option and it will taste just as good. So those are some good options. Anything else you want—Oh, also dessert. Just, you know, if you’re doing a pumpkin pie, you can just leave out the crust are there some really good gluten-free, crust options or you can do coconut uhm— crust option. That’s fine. And you can just do your pumpkin pie without you know, just the lower amount of sugar. That’s totally good right there. Uhm— is or anything else you want to mention for desserts outside of the Apple Crisp?

Evan Brand: I think you covered it. I mean you could bring along a piece of dark chocolate if you’re just super scared and you don’t want to go for any of the more processed things. Bring a cup— bring a bar of dark chocolate with there on the fridge when you get to your family’s house.

Dr. Justin Marchegiani: Yeah. And again, you could do Pecan Pie a little bit higher in sugar. You just have to make sure the crust is gluten-free. That’s totally fine, too. And obviously, just some really good maybe some coconut ice cream, coconut vanilla ice cream’s totally cool. And then what about supplement options? So we talked about, number one, the enzymes, HCL and digestive support. Number two, you could always add in some activated charcoal.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Activated charcoal. Number three, you could always throw in some probiotics later just to kinda help soothe and relax the tummy. Number four, well how about the approach like when do we eat the meals? So, number one, I recommend intermittent fasting and adding in some exercise in the morning. Even if it’s just a quick Tabata, or just a quick little weightlifting circuit where you kinda do upper-lower, upper-lower and just kind of a simple circuit for 15-20 minutes. Just something in the morning to really get the metabolism revved up. You may fast a little bit more. You may hold that fast a little bit longer than normal because you know that your gonna feast at the end of the day and all those calories will be coming in there to make up for that deficiency. Most aren’t gonna be working out on Thanksgiving. They’re gonna be relaxing and so it’s not as big of a deal.

Evan Brand: How about alcohol? You mentioned that off-air. You said we need to make sure we talk about that. So you’re recommending after meals instead of before meals saving?

Dr. Justin Marchegiani: Well, yeah, I recommend just have a little bit. Well, number one, there’s a couple of strategy. So I may do one glass just to kinda get that buzz in my system fast. It’s like, “Ooh, I could feel it.”  And then I’ll throw maybe a couple of things, a charcoal in, and then maybe there will be like a shrimp cocktail out and have a couple of little shrimps just to kinda get the protein, fat in there which kinda stabilizes my blood sugar level a little bit more so I’m not gonna go wonky. And then I typically just go with like a dry champagne or a dry Prosseco. So it’s very dry kind of a demi-sack, not a lot of sugar white and I like the sparkling. The sparkling has been shown to increase alcohol absorption. There was a—one study out of a bunch of college students. Can you imagine that? I would love to have been in the study in college where they gave them shots of vodka and then the other group got shots of vodka with carbonated water or like soda water. And they measured their blood-alcohol content and they found that the group that had the bubbles with their vodka had a much higher blood alcohol content for the same amount of alcohol. So, go figure. So what’s the moral of the story? You get— your alcohol goes for little bit longer of array when there’s little bit of carbonation or, bubbles in there. And James is saying, “What about Cheetos?” Yeah. So I would do Cheetos with my ginger Kombucha and a little bit of lime. The lime provides extra vitamin C, which is great for glutathione. The Kombucha has extra B vitamins and antioxidants and EGCG in there and uhm—probiotics. So it actually helps detoxify and help your gut microbes while you get a little tipsy.

Evan Brand: See that almost makes me wanna drink alcohol but every time I drink alcohol, I feel like I can’t comprehend simple things, like I like to I like to always have my brain going going going.

Dr. Justin Marchegiani: Totally.

Evan Brand:  And for me to shut off with the alcohol, it’s almost stressful. It’s almost like, “Nope, my brain is slowing down.” I don’t like this.

Dr. Justin Marchegiani: Well, we should make sure the demand on our brain is less.

Evan Brand: Right.

Dr. Justin Marchegiani: When the time—we’re not gonna be like opening up the champagne bottles when we’re seeing patients, right?

Evan Brand: Right.

Dr. Justin Marchegiani: We wanna make sure our patients get a 100% of our brain capacity. But when it’s the holidays and we’re just watching some football, and our brain is like 80% off, maybe it’s not that big of a deal.

Evan Brand: <laughs> For sure.

Dr. Justin Marchegiani: Yeah. But, yeah, we have the activated charcoal. We just have really good quality alcohol. Uhm— again, why does it matter? Coz I don’t want a headache. I don’t wanna feel crappy. I don’t want a ton of breakouts the next day. So we’ll choose uh—and typically, I’ll just get $15 bottle of really good dry Prosseco from Whole Foods. And I try to, you know, if I can go organic or you know, typically, the dryer ones are not gonna have as much sugar. It’s the sugar that’s gonna really throw you off. Uhm—you can also do the dry Creek wines. They have some decent stuff. Again, they don’t have a lot of bubbles like a lot of spike, Prosecco, I do that because number one, it helps with alcohol absorption. Number two, I just like the bubbles.  They don’t have a lot of options with that. So I will check out some of the whole foods or local stores, they have a very low sugar like as for a brewed or a Demi-Sec uhm—Prosecco option.

Evan Brand: The holidays are fun.

Dr. Justin Marchegiani: They are. Absolutely!

Evan Brand: I think our next month of episodes is probably be silly. It’s coz that’s the that the holiday vibe. It’s relaxing. It’s like, you know what, the summer time things have cooled off. It’s time to relax, time to rekindle, time to cuddle up, snuggle under your wool blanket next to a fireplace. This is a good time of the year.

Dr. Justin Marchegiani: I got a fireplace in my office so it’s actually nice coz I actually get to use it this time  of the year, so—

Evan Brand: That’s awesome.

Dr. Justin Marchegiani: So my dog just like—it’s basically a magnet for my dog. She just kinda—next to it all day. But, yeah, totally. And then uhm—you mentioned a couple things there. We talked about the alco—so yeah, really getting the exercise component going. Coz that really is gonna wring out a lot of the glycogen in your muscles. So think of glycogen as stored carbohydrate in your muscles and imagine you wringing that muscle out. You’re wringing that sponge out so all of that water in the sponge, all that glucose stored in the muscle now gets used up doing the exercise. Now what does that do? It’s like, well, it’s the equivalent of going and having a nice dry sponge to sop up a whole bunch of liquid drink that your kid knocked over, right? So you can just— that sponge is gonna work a lot better and be more absorbent. Think of your muscles as being more absorbent. So when you get extra carbohydrates into your uhm— body from your meal in your celebration that you’ll have a bigger sponge to soak it up.

Evan Brand: That’s a good idea. I don’t know if many people act on it but if they do, they’re gonna see a really good result. Here’s a question for Mike. He says, “It’s crazy. My Oura ring consistently shows my sleeping heart rate 5 to 15 bpm higher even after having just two drinks like red wine. I feel it the next morning. Any suggestions?” Justin, I know what you’re gonna say. Go ahead.

Dr. Justin Marchegiani: Well, alcohol can drop blood pressure. So it could be your blood pressure is lower than your heart has to be a little bit faster the compensate for that drop in blood pressure. That’s probably what it is.

Evan Brand: So you’re thinking maybe you don’t need suggestions. So I thought you might say, “Oh, just are you doing charcoal? Make sure you do charcoal.”

Dr. Justin Marchegiani: Of course, right? Like of course, extra charcoal. We can always throw some vitamin C in there, add in L cysteine. And we could even throw in, yeah like in our lines, we can throw in some detox aminos which is kind like your sulfur base, kinda NAC with a whole bunch of other sulfur amino acid in there. That— that’d be fine. I mean, I would do that. You can also throw a little bit of magnesium in there to uhm— to help with the with that component. But uhm—yeah, I would just look at potentially that just being the alcohol and just do all the things that help detoxify.

Evan Brand: Okay. Cool. Awesome. I think that’s everything we’ve hit. I don’t know if there’s any other piece to the holidays you wanted to go over.

Dr. Justin Marchegiani:  Yeah. I would try to time off like for me, I notice if I have felt any alcohol in my system when I go to sleep, I do not sleep nearly as good so I tried to give myself like a good three-hour washout period before bed. So I don’t have you know a lot of alcohol in my system. I just don’t sleep as good. I literally have more nightmares, I’m more active, I move around the bed a lot more. I had a glass of champagne before bed like a week or two ago and I like literally woke up at a right angle. So I was like laying across the whole head. I’m just way more active. Normally, I don’t move much at all. So again, if I I had that like at seven and I went to bed at like 10, it wouldn’t be a problem. But if I’m having it right up against bedtime, sometimes it could be the__ plus you know, I’m— I don’t know what the alcohol is when I go out if I order it. I try to order, you know, a nice low sugar kind but you have the bottle in front you look at it, so you just try to go off the waiter’s suggestions.

Evan Brand: Exactly. Yeah. I think it’s all good advice the liver-gallbladder support. I mean, that’s always helpful, too. So if it’s milk thistle or if it’s your Cordyceps mushroom. I mean there’s a lot of different products we use for for liver gallbladder support. One of the thing I was gonna mention, too, make sure that you check in with your practitioner if it’s Justin or myself. If you’re taking anti-parasitic herbs, some of these herbs can get intensified with alcohol. So one glass of wine may feel like four. You may not be able to make it home. See—take a  look and see what you’re actually using. I know some of these can create that sensitivity up.

Dr. Justin Marchegiani: Totally. Any other suggestions just like meal wise or anything that you guys are doing with your family for the holidays?

Evan Brand: I’m gonna bring some snacks just in case. I mean we don’t know the full spread coz we’re gonna go to like three or four different events.

Dr. Justin Marchegiani: That’s tough.

Evan Brand: ..this week and we don’t know exactly what people are cooking, what people are bringing. So just in case, I’m just gonna go ahead and bring uh—I’ve got a couple of some jerky like some jerky strips like some grass-fed steak strips that I’ve got and then I’ve also got a handful of macadamia’s of customer cons would also have coconut chips so I’m just gonna bring some snacks just have that in my wife’s purse just in case just in case we get somewhere and it’s just— I have been to a couple events where it was literally like a casserole, it was covered in cheese and that was the only—that was like the main entrée. There’s no way I could do this.

Dr. Justin Marchegiani: Totally.

Evan Brand:  Like you know, with enzymes, I’d be destroyed so uh—that’s— that’s about it. Just be prepared boy scout. Act like I was going to place that had no food.

Dr. Justin Marchegiani: Exactly. And again, there are some people out there where they may be really happy with her health right now. They’re just like, “Hey, this is a once a year thing and I’m just gonna cheat and really enjoy it. And that’s fine, too. But you know, still you can utilize some of the supplements and strategies we recommended so you at least doesn’t hit you as hard. And if you want to wreck if you want to apply some of the substitutes that Evan and I apply, and I’ve done it for years that in my opinion allow me to continue to feel good. I just— for me, it’s not just feeling good that day. I got four days off  work. I don’t take a lot of time off. I wanna feel good for those four days and I also don’t want to get sick either.

Evan Brand: Yup. Exactly.

Dr. Justin Marchegiani: Well, any other thoughts, Evan?

Evan Brand: I think that’s it.

Dr. Justin Marchegiani: So any other plans for you this week? Are you taking some time off from patients or—?

Evan Brand: Yeah. So Thursday, Thursday- Friday I’ll be taking some time off. My wife she’s can go out and participate in the consumer holiday on Friday. And I think that’s about it. I’m gonna try to spend some time out in the woods. I may— I may go out and and go for a deer hunt again. I want to get my own dear this year. 99% of it is just sitting out in nature listening to the birds but may be .01% of the time an animal walks by.

Dr. Justin Marchegiani: Totally.

Evan Brand: Really, it’s just my excuse to go do some forest bathing. I may try to do that.

Dr. Justin Marchegiani: What’s the Japanese term for that?

Evan Brand: Shinrin Yoku.

Dr. Justin Marchegiani: Shinrin Yoku. I love that, man. That is crazy. Cool. And we also add another herb to our parasite killing line, too. The mimosa Pudica. So I know will be adding that to our stores in the next week or two. It’s one of those things that we are kind of experimenting with. We’re helping to kill bugs and some of the wormies. So it’s something out there that if your patient and you want to inquire about that, we can chat about that very soon.

Evan Brand: Yeah. Stay tuned. I’ve gotten many, many pictures in my inbox of worms that people are pooping out from using this Mimosa Pudica. I was just a guest on the parasite summit, which is how I learned about this formula. And tons of people are taking it now and everybody’s saying, “Oh my God! My stool test showed up negative but I took this stuff anyway. And here’s what I pooped out. Surprise!” And it’s pretty nasty stuff. So Justin and I are talking off like, “Are you going to try some of the stuff?”  I’m guessing we’re gonna have to because we’ve been guinea pigs for everything else. So, who knows if we’ve got some hidden—

Dr. Justin Marchegiani: Absolutely. Well, what a great call today here, Evan. Happy holidays and Happy Thanksgiving for you and your family. And we’ll talk next week.

Evan Brand: Take care.

Dr. Justin Marchegiani: You, too.

Evan Brand: Likewise. Bye.



Justin Health Paleo Apple Crisp




Benefits of a Food Elimination Diet

What are the benefits of a food elimination diet

By Dr. Justin Marchegiani

What is an Elimination Diet?

What is an Elimination Diet?

An elimination diet is an eating plan whose goal is to determine food allergies and intolerances. It is a short-term plan, usually lasting between 3-6 weeks, that allows a person to learn which foods may be causing digestive distress, skin irritation, and brain fog. In an elimination diet, certain foods are cut out of the diet for a few weeks, before being slowly reintroduced, one-by-one, in order to pinpoint troublesome foods.

What to Eliminate

 Foods To Eliminate

The law requires foods to be labeled if they contain common allergens. The eight foods identified by the FDA are:

  • Milk
  • Eggs
  • Fish (e.g., bass, flounder, cod)
  • Crustacean shellfish (e.g., crab, lobster, shrimp)
  • Tree nuts (e.g., almonds, walnuts, pecans)
  • Peanuts
  • Wheat
  • Soybeans

These eight foods constitute over 90% of allergic reactions! However, allergy tests don’t pick up on food intolerances and sensitivities.

Foods to eliminate in a food elimination diet include some of the common allergens listed above: gluten, dairy, soy, and nuts, but also encompass the common culprits of inflammation, digestion issues, and brain fog. These include nightshades (eggplant, peppers, tomatoes, and potatoes), alcohol, and processed sugar!

Click here to consult with a functional medicine doctor to diagnose and treat any food sensitivities!

Benefits of a Food Elimination Plan

Food elimination plan benefits

Eliminating sources of inflammation will allow your body to heal and can enact a plethora of positive changes within your body.

Recovery from Leaky Gut Syndrome: Leaky gut occurs when the intestinal lining becomes inflamed, which can be caused by the consumption of gluten, sugar, or other foods you are sensitive to. The inflamed gut lining allows food particles and other toxins to slip through into the bloodstream, creating more inflammation. By eliminating the foods that cause the gut to become inflamed, it is possible to break the cycle and heal your gut!

Reduce skin irritations, such as eczema and acne: Dairy and grains are two food groups which studies have shown have a strong link to acne and other skin irritations. Try cutting them out of your diet and watch your skin clear up in just a few weeks.

Prevent/treat learning and attention disorders: Studies have shown that a strict elimination diet can treat symptoms of (and in some cases defeat!) ADHD. There is promising research showing that even just avoiding artificial colors and preservatives can also lessen symptoms.

Reduce migraines: You may have heard the gut referred to as the “second brain.” In addition to all the functions, the gut is in control of, the gut actually communicates with your brain as well! An inflamed gut (due to consuming “bad” foods), can send signals to your brain signaling migraines and headaches.

Reduce bloating, diarrhea, and constipation: We’ve all experienced the feeling in our stomach after eating something we know we shouldn’t have had. Eating problem foods causes a relatively immediate stomach ache and possibly diarrhea, but regularly eating foods you are sensitive to – even unknowingly – can actually cause long term gastrointestinal distress! People who have gone on food elimination diets often say they didn’t know there was something wrong until they cut out the foods that were causing them to suffer. It’s like a weight lifted from your shoulders!

Bonus: add in a quality probiotic supplement to help your good gut bacteria rebuild!

Help heal autoimmune conditions: Food sensitivities can create and worsen autoimmune disease. Not only is it possible to stop the severity of your autoimmune disease from worsening, but it is even possible to reverse your autoimmune disease by removing inflammatory problem foods!

Starting a Food Elimination Diet

How to start a food elimination diet

If you suffer from digestive distress, skin breakouts, rashes, or suspect you might have a food allergy or intolerance, an elimination diet is always a good idea. The antibodies your immune system makes when it reacts to a problematic food you’ve eaten take about 3 weeks to dissipate; imagine feeling like a whole new person in only 3 weeks!

A food elimination diet generally last between 3-6 weeks, and can focus on one or two specific foods, or it can target a wide range of foods. For a preview of what an elimination diet looks like, and when to add foods back in, check out our post outlining what you can eat and when you should reintroduce foods.

Consult with a healthcare professional to determine your best plan of action!







Using Spore-based Probiotics (Sporebiotics) to Improve Your Health – Live Podcast #157

Dr. Justin Marchegiani and Evan Brand talk about spore probiotics and their importance in modulating the immune system. Learn about Th1 and Th2 immune system, understand the negative effect of vaccines on them and know the role of  probiotics in the imbalances created by vaccines.

Gain information on some of the probiotics strains and know how their acidity and timing of intake impacts absorption. Discover the answers and explanations to questions about lectins and digestive enzymes in relation to probiotics. 

Sporebiotics to Improve Your Health

In this episode, we cover:

03:00   EMF’s and Infections

06:29   L. Gasseri and Histamine

09:16   Th1, Th2 immune system

18:55   Paleo template and IBS

24:48   Lectins






Dr. Justin Marchegiani: Yo, yo, yo! It’s Dr. J here in the house. It’s a great, magnificent Monday. I got my little Topo Chico, a little sparkling bubbles here. Evan, how was your weekend, man?

Evan Brand: Oh, life is good. I don’t remember the weekend. The weekends are so weird once you have a baby. I’m sure you figured out the same thing. The weekend is just like, it go by and then all of a sudden, it’s Monday again. And I just love working so much that it’s like, “Oh, it’s Monday, my favorite day of the week.

Dr. Justin Marchegiani: I feel the same way, too. I love Mondays coz I love getting back in the swing and creating content and seeing patients and getting all these uh—great feedbacks of people getting better or you know, you get challenging cases that really cause you to roll up your sleeves. So I definitely like that, for sure.

Evan Brand: Me too. And how was it for you?

Dr. Justin Marchegiani: It was great.  Uhm—this weekend, my wife—coz we’ve been—we had a baby like a month and a half ago, it’s the August 21st and for the first, she went out Friday and Saturday night. And I had babysitting duty. It was great.

Evan Brand: Oh man, I’ve never done that myself_ the 15th month old.

Dr. Justin Marchegiani: Not yet? Yes. She went out and she gave me a bottle, you know breast milk in a bottle. And just gave me uh—you know, a little bottle but, you know, it created a little balance there because she’s been basically breast-feeding often on every hour or two for the last six weeks. It’s hard because she was—

Evan Brand: Did she text you the whole time missing the baby?

Dr. Justin Marchegiani: Well, I was kinda giving her updates. But she was feeding, doing the SNS and then pumping and then the time that all finished, the next feeding started in 45 minutes. You can imagine that for five or six weeks. It’s really hard. Now it’s getting like two hours after or an hour and a half to two hours. So now it’s like, “Oh, it’s getting a little bit better.” You know, two hours, you can at least close your eyes and get a little bit of be restorative sleep in there. So that’s good.

Evan Brand: That’s great. Cool. So you were uh—you were the babysitter.

Dr. Justin Marchegiani: That’s it, man.

Evan Brand: That’s awesome.

Dr. Justin Marchegiani: Life is— it’s crazy how life is, man. Just things continue to evolve and you get satisfaction out of different things. You wouldn’t think it. Holding your baby and having them smile at you or just hold your finger whatever could be that satisfying but—ain’t it funny how that all changes?

Evan Brand: I know, man. It’s great. It’s like DNA trick. So we’ll take care of them.

Dr. Justin Marchegiani: Exactly. Now, we wanted to talk today about the probiotic, speaking of DNA. We want to talk about probiotics. And probiotics—again, we’re gonna hone the topics. We talked about probiotics before but we’re gonna really address the area of spore probiotics which are like the cell walls of the specific spores called bacillus spores. There’s a couple that we use in our clinic called Bacillus Clausii Subtilis and Coagulans. Bacillus Coagulans, Subtilis and Clausii. Those are the big ones that we use and these are the basically the cell wall of these kind of bacteria which is the spore. And they have an awesome, awesome benefit of modulating the immune system. Couple other things we find – a lot of these microbes in our body— fungus and bacteria and parasites— EMF’s or electromagnetic frequencies have a real negative effect on making these infections worse. And what refining is some of these bacillus strains, some of the spore strength can really help combat against the negative effects that EMF has with some of these critters. That’s another good benefit. I’ll open up the floor to you here, Evan.

Evan Brand: Yeah. So EMF— I mean I’ve done episodes on this since the inception of the podcast in 2012. So it was five years of talking about it in some shape or form. The more I learn about it, the more that I learned it affects everybody’s systems. So like you just say, uh—I’m gonna say it in a different way. The EMF can actually strengthen the virulence of these infections. So someone’s got parasites, yeast, fungus— we may need to look at bringing probiotics in and really upping and upping and upping the beneficial bacteria to try to counteract the effects of EMF. Now just because you’re not sensitive to EMF, doesn’t mean that it’s not a factor, right? You might not have the headaches or the— the ringing of the ears that a lot of people talk about where the heart palpitations. Like you may not have true EHS like Electronic Hypersensitivity Syndrome or EHS or they have different names for. If you’re not that sensitive, it doesn’t matter. You’re still going to benefit by protecting yourself and protecting your microbes by using either these bacillus spores that we’re going to talk about or just by using other types of probiotics. And at the right time, uh— one thing I wanted you to hit on Justin is talk about the timing of bed and how we can work this in because many people go to whole foods and they buy a probiotic and they take it and then come back to us and they say, “Dr. J and Evan, I took probiotics and I feel worse. What’s going on?” It’s all about timing.

Dr. Justin Marchegiani: Yes. So there’s a couple different things. So a lot of probiotics like your bacillus uh—sorry—your lactobacillus, acidophilus, right? Your bifidobacter kinds of probiotics, right? These probiotics tend to be more acid-sensitive. Now there are some that Evan has in his line that are acid-resistant because during this—this like a sphere that it kind of is acid-resistant. And taking that and kinda get through some of stomach acid. We may also just hide it on an empty stomach to bypass the stomach acid so we can have that bacteria intact when it gets to the small intestines, the colon. And then we can have a lot of benefits with immune modulation. We can have uhm— a lot of benefits of boosting up the healthy bacteria so we get better B vitamin pers—uhm— increase coz we get the good bacteria produce a B vitamins. Also, healthy bacteria, I know with the bacillus strains that we see, one of the great things as it helps convert sugar to vitamin C. And vitamin C is super important for collagen, for immune function, for oxidative stress, right? Oxidation is the apple that you cut open then it sits on the countertop and turned brown or the nail left outside that gets rusty. That’s oxidation. That’s a loss of an electron. Antioxidants like vitamin C can help donate electrons to prevent the oxidative stress. So healthy bacteria and particularly the bacillus strains can really help with the vitamin C uhm— conversion from sugar, which is great. And then your other strains like the bac—like the lactobacillus acidophilus, right? These produce acids, which are great coz acid– acidic environment actually keeps a lot of the bad bacteria and fungus in check from growing. That’s why a lot of people do great with apple cider vinegar. It is like this cure-all because the acetic acid has got a very low pH that makes it really hard for microbes and not so nice microbes to work and also can stimulate your own HCl production as well.

Evan Brand: Yup. We have a question from Haley. She said she read that the strain L Gasseri reduces histamine. Have you ever heard of this? Yes. I have heard of certain strains of probiotics helping to reduce histamine. I don’t know if this is correct, but I remember seeing that the Rhamnosus species—I could try find this journal I had bookmarked— I believe the lactobacillus Rhamnosus was something that actually increase histamine, which is why some people may feel worse. I just found it here. Histamine production by lactobacillus Rhamnosus. And Haley just said she read other strains can increase. Yeah. I’ve read the same thing as well, which is why typically, we’re gonna use a combination. And we’ll likely going to have a blend. So if you’ve got some things that are stabilizing histamine, you’re typically going to counteract the other one that could increase histamine.

Dr. Justin Marchegiani: Yeah. Again, people that typically are histamine-sensitive, a lot of times probiotics in general can create histamine intolerance. Uhm— so I see a lot of people that will just do a really good, you know, lactobacillus or bifido bacter or lactobacillus plantarum, whatever, like that may cause them to get bloated or gassy. If they are probiotic intolerant, one of the things we go to is we go to a spore-like probiotic because people that are histamine-sensitive tend to be able to tolerate that well. And one thing we like about the bacillus spores is it’s acid resistant. So you can actually take it with food, which can make it a little bit easier to process than taking it may be on empty stomach. So we like that.

Evan Brand: Yeah. Now, like you mentioned, you and I use some specific types of probiotics out there. They can have an encapsulating technology, where you can reserve them.

Dr. Justin Marchegiani: Yes.

Evan Brand: So this doesn’t mean that you have to ditch all other probiotics. It just means unless you’re using the formulas that Justin and I have, if you’re not using ours, then you want to use a spore-based because all the other ones, unless it says, “Hey we’ve got some special— if you’re looking at the label— unless it says, “Hey we got a special tableting technology that protects from stomach acid” you’re kinda wasting your money on most of the probiotics.

Dr. Justin Marchegiani: Oh, absolutely. I know the ones that we typically use they will put like colony forming units on there, which you know, that’s like how many probiotics that are in there. There’s a couple of things to look at. Number one is— is that the colony forming units of the probiotic that were put in there when it was bottled? Or how many they expect to be in their expiration one or two years later? So number one, when we put the CFU on that bottle, that’s gonna be how many we expect to be there in 1 to 2 years later when it expires. So, you’re ideally adding so many extra in there. So you’re compensating for potential things that may knock it out like heat or shipping or storage stuff. Just things that are normal with getting that product to the patient. So when you know what’s in the bottle there, you’re typically getting more than what’s in the bottle because we have to make sure we overshoot and compensate for all the little mishaps that may lower it.

Evan Brand: Right. Well said. So, talk about the immune system a bit. You wrote some notes before the show about the TH1 and the TH2 immune system. Can you talk us through that and kinda break down what TH1 is, and 2, which some of us are TH2 dominant in the modern world now mainly from vaccines. And that the TH1 system, this kind of seesaw can be balanced out with the use of these spore probiotics.

Dr. Justin Marchegiani: Yeah. Great question, Evan. So a lot of people their TH2 immune system is over stimulated and your TH2 immune system— think about it— it’s the antibody-based immune system. It’s the humoral-based immune system. So the whole goal of like your immune system is you have like the front-line defense. This is like the Army Rangers, the Delta team; Seal team six, the Navy SEAL’s, right? These are the people, they get in there first and they make—they make stuff happen, right? These are the guys that go in there first. They radio back and then the infantry comes in second, right? So they give the infantry, they come in a few days later once they got Intel and you know everything’s been surveilled, right? All the special forces, they radio in the special forces are the cytotoxic or the natural killer kind of that cytotoxic first branch of the immune system, the TH1. And the TH2 is kinda more that delayed antibody-based immune system that comes in after the fact. And when we look at what vaccinations do is they boost up to give a little bit of that compound that you’re trying to develop an immune response to i.e. the infantry and you’re trying to boost that up. So you’re trying to keep basically this infantry that’s hanging out, that’s waiting—that’s waiting for that critter to come in. The problem is when you boost up that infantry more, more, more, more, more, more, well, there’s collateral damage that can happen like allergies and other issues on the immune side if you continue to boost it up too high. And that’s why one of the big trade-offs that has happened with a lot of vaccinations over the years is a lot allergies, there’s a lot of ADD, there’s a lot of other parts, a lot of symptoms that can happen just because that a part of the immune system is so over stimulated. And when we dig to some of these bacillus spores, right? That can help knock down the TH2 by boosting up the TH1. Think of it as a seesaw as one side goes up, one goes down. So when you boost that TH2 up so high, you’re basically decreasing that cycotoxic, those Navy SEALs, those Army Rangers, right, that Delta force, right, that were lowering that. So by knocking that seesaw down on the  TH2, we do it by boosting up the TH1 and those bacillus force can be super helpful at doing that.

Evan Brand: Yup. And medicinal mushrooms, too. We can stack mushrooms on this.

Dr. Justin Marchegiani: Yup.

Evan Brand: …with these and we can help modulate TH1. So—

Dr. Justin Marchegiani: We can totally do that.

Evan Brand: We got a couple questions. We have one about food combinations, we have one about infrared sauna. Here’s one from Tessa that’s on-topic about probiotics. “Is it good—is it good to take with digestive enzymes?” I guess you’re saying, “Is it good to take digestive enzymes and probiotics together?” My answer would be no. Generally, just because the stomach acid is likely going to kill those. Now even if you are taking a super high professional grade formula like Justin and I are using with you, still, we don’t want to try out a breakdown that technology. If we can preserve those bacteria and get that to the colon, where it’s really gonna do the good thing, I would take your probiotics before you go to bed. Because there’s no competition for stomach acid at that time.

Dr. Justin Marchegiani: Exactly. Yup. So I think taking up probiotics in the morning when you get up first thing or before you go to bed at the very end. Take your enzymes with food typically you can do enzymes before meal, too.

Evan Brand: Uh-hmm.

Dr. Justin Marchegiani: Uhm—again, but typically, with the meals also fine as well. And regarding uhm—did you ask about food combining, yet?

Evan Brand: Well, I didn’t read the question yet. I just said best food combinations. Once you can’t go wrong with like meat and salad.

Justin M: Yeah. It’s typically meat and non-starchy. Meat and non-starchy vegetables, chicken and broccoli. Those kind of things. Typically, fruit by themselves. Again, that may cause blood sugar stuff. So, again, I typically only deal with food combining stuff where maybe starch and fruit are eaten a little bit away from things if there’s a lot of digestive issues. And if there’s a lot of like fructose malabsorption, when you really can’t digest much fruit either, fruits gone.

Evan Brand: Yeah.

Dr. Justin Marchegiani:  And they may not be able to tolerate much starch. And again, some of these changes when you go lower FODMAP, too. When you go lower FODMAP fruit or lower FODMAP starch that may get better. And if you also up the HCl and the enzymes, some of those symptoms that you may see a relief from when you food combined correctly, right? You may not need that.

Evan Brand: Yup, well said. There were two other things we wanted to mention about the TH1, TH2 system. One, you mentioned like ADD or you know, some type of developmental problems like autistic children, they could have an issue with—with their TH1, TH2 balance. So this is where the spore biotics can come in to the equation and fix it and then also food sensitivities. Now a lot of the stuff gets better, too. You know Justin and I talk so much about parasites things like H. pylori infections, bacterial infections that are suppressing stomach acid. So food intolerances are typically related to the gut, but also, we found that this whole immune system thing can also be a factor and just by getting more beneficial bacteria and the right strains as well, all the sudden food sensitivities go away and you can start adding stuff back in that you used to not be able to tolerate.

Dr. Justin Marchegiani: Yeah. Some of that just because there is a little bit of peanut oil sometimes in some of the vaccinations as a preservative and uhm—there’s also uhm—some proteins in there. So a lot of peanuts, you know, peanuts the last 20 years has been a huge one. I mean you can’t even take a lot of times peanuts into a regular elementary school.

Evan Brand: I know. It’s crazy.

Dr. Justin Marchegiani: So I think that’s part of it. I there’s a lot of theories that are out there saying that. So, I mean, may not be super hard evidence on it, but we know that the amount of vaccines have, you know, triple, quadruple over the last 20 years since 91 really—1991. That—that could be a driving factor. That would make sense, for sure.

Evan Brand: Yeah. I was glad uh—Eric Berg. He put out a video about vaccines. Did you happen to see that one?

Dr. Justin Marchegiani: No, I didn’t.

Evan Brand: He has a good video. Look it up when you got time. But  it was a good video. He was just like, “What’s my take? People asked me.” He’s like, I don’t like him.”  And he’s got full list of all the different things that are inside of those and then plus he talks about all the different things that were deemed safe by the FDA like DES that all those women were taking and then you have all these different birth issues—

Dr. Justin Marchegiani: Thalidomide—with the—with the kids with uh very short arms.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Totally. And again, on the vaccine, though, too, if you look at—there’s a big study that was done. I think in 2014. But they looked at kinda vaccine dosages across, you know, how many dosage, or how many individual vaccines across all the countries. And I think it was a lot of the Scandinavian countries that had 75% less vaccinations and better health— better overall health.

Evan Brand: Right.

Dr. Justin Marchegiani: So I mean, I think just kinda keeping in mind that there may be some benefits from vaccines, but it’s not health never comes from a needle. Not just because you get a vaccine, it does not replace sleep and nutrition and hydration and obviously, a cleaner environment, too, which is huge, right? Plumbing and those kinda things make a massive difference when it comes to infectious disease. But these countries show that you know, much less vaccines dosage-wise, huge difference. I mean they were much— you know, far beyond us health-wise.

Evan Brand: Yup. So if you can’t go back in time and change how you were vaccinated as a kid, this could also give you inspiration about how you approach adult vaccines. Coz now I’ve got a lot of clients I know you do, too that are approaching us and asking us about shingles vaccines that the doctors are really pushing hard for people over age 60. And then also the flu vaccines, which I’ve had people who get the flu after they got the flu vaccine.

Dr. Justin Marchegiani: Yeah. It’s a live attenuated virus. You look on the vaccine inserts, it’s 20% chance of having flu-like symptoms because of the vaccine. It’s on the insert. I mean this isn’t even controversial stuff, unless you actually go in there and ask for the vaccine insert like I have. And then you just_ the side effects and you say, “Hey, look here’s a side effect right there. And it’s I mean, chills, malaise, headaches, you know, achy, tired—that sounds like the flu to me. What do you think?

Evan Brand: It is. I mean, well, it is the flu. And the issue, too, with the CDC is that when they’re making those flu vaccines, they’re only coming up with certain strains, right? So if there’s another strain outside of the one you got vaccinated for, you’ll still get the flu that year and still feel terrible.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Plus, you’ve got the aluminum and what other preservatives or things in there that are activating that virus for your or—

Dr. Justin Marchegiani: Right. Totally. So kinda the idea is when the vaccination side is your manipulating your infantry, right? You’re boosting up, you’re getting a special reserve of that infantry that’s gonna be specially trained for that one little critter that comes into your body, which you know, definitely has uhm—some use for. Now, my philosophy is let’s just get your immune system so freaking strong.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Let’s get all these infantry guys lifting weights and— and you know, rock-solid with the nutrition and diet, so then they’re so ready to go. They’re gonna just plow through any critters and that’s kinda what we’re talking about with all the diet, lifestyle, the nutritional support, uhm—the nutrients to up regulate the immune system, the probiotics like mega spore biotics is one that we use. We’ll put a link below for the link here, my store for that. If you wanna see that. It’s the one that I use. It’s a bacillus clausii, subtilis and coagulans strain that can help balance that TH2, drop it out, pop the TH1—that’s great. Uh—also, medicinal mushrooms like __and other herbs, too. Astragalus,__—

Evan Brand: Yeah.

Dr. Justin Marchegiani: Andrographis, uhm—silver, vitamin D, of course, glutathione. These are all great immune modulators so we can really get that infantry boosted up and stronger, right?

Evan Brand: Yup. Perfect. Rachel, nice to see you. She’s got a question, “My husband was regular before we went Paleo / Primal, but since about two years, he’s slower, no longer pooping daily, we eat lots of veggies, he’s not a stress personality type. Any advice to improve? Justin, what do you think?

Dr. Justin Marchegiani: Well, off the bat, very simple. I would look at just increasing a little bit more starch, little bitt of sweet potato that may shift things, number one. Uh—n number two, make sure the veggies are cooked if you’re doing this more raw stuff, and that’s causing him to backup, do a little bit more cooked, steamed, sautéed— that’s number two. Number three, adding some enzymes and HCl. Uhm— and then number three, get your gut looked at. If there’s still issues with maybe dysbiosis. What happens is sometimes that starch can help feed some of that beneficial bacteria and that gets drop-down when the starch goes down. So pop it up a little bit of sweet potato, plantains, squash, may give that good bacteria a little pop. Uh— but in the meantime, it’s just as a palliative. Uhm— not pooping daily, not passing 12 inches of stool daily is not good. You get something called autointoxication where you start to reabsorb a lot of the toxins in your stool. So a little bit of magnesium citrate daily to keep those bowels moving and then taper off uhm— down the road. You know, give yourself a few weeks to kinda make those changes and see if you can be regular on your own.

Evan Brand: Rachel, I believe you’ve got your stool test back from— from me. Uh so look on there, too. Uh—you know, one thing that I would suggest, too, get your husband a stool test and look at the beta glucuronidase enzyme like Justin is talking about with autointoxication piece. We can measure that with the enzyme and we can fix it. Milk thistle and supporting the liver and getting rid of gut bugs but you know, if there’s H. pylori or parasites or other bacterial infections that he could have, you guys could be passing things back and forth. The infections could be slowing down the motility. I just put out a podcast with this guy, Ken Brown, who’s a gastroenterologist and he was teaching me more about methane and how certain species of these uh— bacteria during SIBO cases are actually slowing the bowel transit time. So, literally, bacterial overgrowth could just be the culprit due to the methane production. And of course, he’s selling his supplement to reduce methane but if you just fix the SIBO, that will also get your bowels more regular. So I hope that helps.

Dr. Justin Marchegiani: Love it. Very cool. Well, anything else you want to add about uhm— spore based probiotics?

Evan Brand: I think it’s something that should be in everybody’s toolbox. I don’t know if it’s the silver bullet. I don’t know if it’s the—you know, a lot of people find something that helps them, so then it’s like this is the only thing you can use out there. I still think there’s other benefits to other probiotics that we use, but I do think it should be in everyone’s toolbox and they should at least consider looking at it and potentially using it. Could you just randomly go and take it if you’ve got a bunch of symptoms? What’s your take? I’ve had so many people take probiotics so willy-nilly and they feel worse. So I really think it’s important to get tested first before you spend your money on this.

Dr. Justin Marchegiani: Yeah. I find that’s— it’s one of those things where it is other deeper issues there. It’s not gonna be a root causal thing, right? There’s too many other things going on in motion. The more other things are happening in motion, and they aren’t stopped or they aren’t addressed, that it may help a little bit, but it may make no difference at all. So I always say get the low hanging fruit under control and then if you want to add it, then great. If you want to work with a functional medicine provider like us that kind of get things lined up for you, make sure everything’s in order, and then add it in. Some patients I see, it really doesn’t change anything; Some patients, it makes it a little difference; some patients, it makes a huge difference. But we’re not ever hanging your hat on one thing, but sometimes one thing can make a big difference but we never expect to. So then we’re always pleasantly surprised if we get one of those great cases.

Evan Brand: Yup. Well said. Well, I’d say, before we just become a rambling man, we can wrap it up. I think this was a helpful episode for people. Add it to your toolbox, do a little bit of research. I think we may have done other shows. I’m sure we hit on probiotics all the time, but—

Dr. Justin Marchegiani: I think so.

Evan Brand: But if you’ve got, if you’ve got people in your family that have issues maybe they just won’t change the diet, they could potentially get benefit. Maybe if you’re looking for that one thing to try to get someone started into this field of functional medicine, maybe that spore probiotic is the first step. And then maybe that excites them and that encourages them to pursue the diet, the lifestyle, the sleep, the stress, the infections, the testing and all that. If that’s the catalyst, then that’s awesome.

Dr. Justin Marchegiani: Yeah. How we talk about any supplement is in kind of context of a whole program. Like we’re doing all these different things, we’re addressing all these things and then this is another maybe piece that we plug into. We’re not saying, “Oh, we plug this piece into someone who doesn’t—who’s not doing a darn thing.” We’re plugging it into a program.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Where everything is being looked at. So that’s just kind of our context. S if you’re one of these people that aren’t on a program or aren’t doing anything diet or lifestyle wise that’s really healthy and then you think it’s gonna be that magic bullet, just want to make sure we set your expectations accordingly. And just, you know, don’t forget that majority of antibiotics aren’t just true antibiotic prescriptions if they are in the food supply. So being more organic and eating healthy animal products healthy fats, that’s gonna be helpful so you won’t get that antibiotic exposure which will throw off your gut. And healthy gut bacteria, it produces nutrition, right? Uhm— good bacteria eats, poop and poop nutrition. Bad bacteria eats nutrition and poop. In other words, back it up. Good bacteria provides nutrients in your body just like I mentioned with the spores and the vitamin C which then helps with vitamin K which then helps with vitamin D, of course, and healthy bones, too. But it also—the bad stuff produces a whole bunch of crappy toxins. LPS, lithocholic acid, etc. These things help open the gut lining, make your gut a little bit more leaky which then gets that TH2 immune system overreacting because you got all these undigested food particles that you start developing an immune response to. Not so good. That really gets your TH2 now even more jacked up.

Evan Brand: Yup. Well said. We have one question from Neil. He said, “Do you think lectins are an issue?” Some are saying lectins are real problem, other say beans and legumes are one of the common factors of the blue zone areas. The blue zone, for people listening, that’s like the people that are living to 9000+ years old. They are eating a lot of beans and such. “Love the podcasting.” Thanks for the feedback, Neil. Justin and I when we talk about grains, for example, like with rice pressure cookers, the way to do it. If I do any organic white rice, it’s typically like a treat for me. I put it in the pressure cooker I tend to feel much, much, much better. But beans, I don’t really do beans. Justin, what’s your take?

Dr. Justin Marchegiani: I’ll do beans every now. Uhm—but like maybe once a month, but it’s all about context. Let me give you, for instance. “Evan, our massage is good for you.

Evan Brand: (laughs) I would say yes.

Dr. Justin Marchegiani: Okay, great. Our massage is good for you. Do they feel good when you have a really bad sunburn?

Evan Brand: Oh, not really.

Dr. Justin Marchegiani: No. Well, think of your gut as like a sunburn. Like your gut, it’s all irritated and inflamed with critters. So the more sunburn and the more intense that sunburn is, the more you may not be able to handle things that have lectins or these gut-irritating compounds in them. So the sunburn gets better, you can handle that nice massage. Your gut gets better and healthier and more infection-free and more good bacteria build backup. Could you tolerate a little bit of uh—legumes here and there? Yeah, more than likely. Some may not, right? There’s not a be-all end-all thing but some may. So it’s all about the context. Typically, the less inflamed you are, the better ability you have to adapt to a stressor like lectins, for instance.

Evan Brand: Yes. So now I’m gonna say the guys name because I don’t want to give them anymore—uh—anymore press he deserves. But there’s a lot of anti-lectin people out there—

Dr. Justin Marchegiani: Yeah.

Evan Brand: And it’s just like, to me, it’s a sales pitch. It’s probably gonna sell a lot of books coz it’s like, “Oh, my God! Plants are bad for you.” And then I had people emailing like, “I might as well just starve to death. I can’t eat this, I can’t eat that. I might as well starve to death.” And I just—I’m not a fan of any—I’m not a fan of promoting things that instill fear in people. I agree with your analogy. I miss your analogies, by the way. That was a good one.

Dr. Justin Marchegiani: That was a good one, right?

Evan Brand: Did you come up with that right on the spot?

Dr. Justin Marchegiani: Off-the-cuff, man. It’s how my brain thinks. If I can’t create that analogy, if I can’t wrap my head around it, I can’t expect, too, either.

Evan Brand: Well, that was a good one. And so back to my point. I don’t want to instill fear upon people. I agree with your—your strategy and your analogy. Lectins— sure, if you did beans and rice every day, maybe you could have some issues. But if you’re infection-free, your adrenals are healthy, you’re going to sleep on time, you’ve got good relationships, you like your job, you like your boss, you’ve got a great spouse, like you could probably do more lectins, more rice, more beans whatever. And maybe you could get away with it and feel okay.

Dr. Justin Marchegiani: Yeah. If it was in your 80-10 or 80-20 or 90-10, yeah, you know, it’s part of your 10 or 20, you probably would be okay, borrowing all the things you said.

Evan Brand: Yup. I’m sure we can ramble on about that point. That was a great question, though. Uh—

Dr. Justin Marchegiani: And then, also, too, certain foods and have more lectins. Of course, grains are going to be the bigger offender, right? And then you know, you have your legumes, right?  Your beans or lentils, but you know, just soaking them has a huge reduction in getting those lectins down. And even vegetables that do, just cooking them can have a huge effect on reducing some of them. So a lot of times, it’s not just the sheer amount. It’s well, how can you prepare to reduce those lectins as well.

Evan Brand: Yup. The pressure cooker for me has been a game changer for the rice.

Dr. Justin Marchegiani: Yeah. And just the Paleo template or autoimmune template is a start. I think has probably the best effect at reducing most of those right there, off the bat.

Evan Brand: Yup. Tessa had a question. “My brother has celiac disease. Are probiotics a good idea in his case?

Dr. Justin Marchegiani: Well, you—you’d wanna really do a bunch of things, but would probiotics be a part of that plan? Yeah, absolutely. You do a six-hour protocol with this. You’d remove the bad foods. You replace enzymes, acids. You would repair the gut lining and the adrenals and the hormone systems. You remove the infections. You retest or you repopulate healthy probiotics, then you retest.

Evan Brand: Yeah, I agree. Celiac is quite a bit—celiac is the manifestation, but there’s probably 5-6-7 puzzle pieces that have to be laid out.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: Probiotics maybe 5% of the equation, it may be 15%, who knows until we—

Dr. Justin Marchegiani: Yeah. And if you add in some good probiotics, like in my line Probio Flora or something like that. Would that be helpful?  Yes. But if he did it in conjunction with drinking his wheat beer and continuing to eat grains all day, it may be like using—it may be like using a beautiful golden nail on some rotten wood. It’s just like, “Argh, it’s not enough.”

Evan Brand: Right. You got to go deeper. Even the diet— we’ve had celiac clients and patients that come to us where even the diet is not enough because it got infections that are tearing apart that gut lining, creating that leaky gut situation and they’re reacting to everything. So even the Paleo or a gluten-free diet may not be enough. And usually it’s not. That’s why we do what we do.

Dr. Justin Marchegiani: Bingo. Love it, man. Hey, let’s chat again real soon. We got information coming up for our listeners. Have a great rest of the week, Evan.

Evan Brand: Take care. You guys, if you need to reach out, justinhealth.com evanbrand.com We are available.

Dr. Justin Marchegiani: And if you like the audio quality, guys, give us the thumbs up. We’re making some tweaks, we’re making some changes. Give us a share. Sharing is caring. We appreciate it. Leave a comment below. We wanna know what you think about. Give us feedback. You drive kinda what we want to talk about next and we’ll answer those questions to you, too.

Evan Brand: Yeah. Don’t be a lurker. Give us some comments. Your comments are our oxygen.

Dr. Justin Marchegiani: Absolutely. I don’t want you creeping in those YouTube post. We want you out there kinda getting some good info. We appreciate it.

Evan Brand: Alright. Take care.

Dr. Justin Marchegiani: Evan, take care, man. Bye.






Low Body Temperature! – Dr. J Live Podcast # 156

Dr. Justin Marchegiani and Evan Brand engage in a very informative discussion about low body temperature. Learn how different potential stressors like thyroid issues, adrenal issues, gut health, autoimmune conditions, nutrition and low calories cause low body temperature. Find out about the role of micronutrients in thyroid hormone conversion and be aware of the medications that have a negative impact on mitochondrial function.

Gain information about the different foods, including modifications in macronutrients, and various supplements, which will improve your health and prevent different stressors that are possibly causing low body temperature.

In this episode, we cover: low body temperature

03:27   Thyroid issues

07:05   Beneficial Nutrients

14:14   Toxins and Medications

22:51   Food and Supplements

33:46   Calorie Intake






Dr. Justin Marchegiani: And we are live here on YouTube. It’s Dr. J in the house. Evan, my man, how are you doing brother?

Evan Brand: Hey man, happy Monday! We’re talking all fair about that shooting this morning so my mom, she worked right next door last night at the Hotel Luxor which was uh— right next door to that shooting event in Vegas. So I called her this morning and she’s safe and sound and she got released, so she’s home, hopefully sleeping. I’m sure she’s extremely adrenally stressed at this point, but hopefully she’s resting and settling down from all that.

Dr. Justin Marchegiani: Yeah. Lots of empathy for all the people out there going through that. It must be just incredibly stressful.

Evan Brand: It’s insane.

Dr. Justin Marchegiani: It’s just so difficult. So wishing everyone, you know, speedy recovery from that. That is just so difficult and man, everyone’s adrenals are revved up from that, right?

Evan Brand: I know.

Dr. Justin Marchegiani: So let’s go into some stuff here where people, we would get— put some information out there about improving everyone’s health.

Evan Brand: Yes.

Dr. Justin Marchegiani: Uh—and just continue to empower more people. So let’s dig in, brother.

Evan Brand: Yes. Yes, so you and I want to chat about low body temperature, which is something that so many people have. I’ve had it in the winter for a long time. I’m hoping that since I work so much, my gut and my adrenals that I don’t have it this winter but cold hands, cold feet you know that had been something that I mentioned going on with me for—for several years. I know there’s a lot of different causes that you and I wanted to go through. So how should we open this thing? Should we talk about hormones, thyroid, how do you want to lay the groundwork?

Dr. Justin Marchegiani: Oh, we look at body temperature. Temperature is probably one of the best indicators of your metabolism, right? Because the more energy you have, typically the— the better your temperature is. And so typically, you’re gonna have symptoms of cold temperature which are gonna be cold hands, cold feet those kind of things. Also, fatigue, but now there’s also objective ways that we can test your temperature. You know, with the thermometer, obviously. We can do axillary temperature, which is armpit. 97.8 to 98.2 is—is Fahrenheit is a pretty good range to be in. Or 98.2 to 98.6 orally. And so you can kind of assess your temperature. You can do it in the morning and then you can also do it in the afternoon as well. Kinda do it just for before eating. That gives you a pretty good indication but if your metabolism is low and your temperature is low, it could be caused by an interplay of different things. We’ll go into it. It could be thyroid issues. It could be adrenal issues. It could be gut issues. It could be nutrient issues. It could be mitochondrial issues. So all of these things are potential stressors that could be driving that problem.

Evan Brand: I’d say number one is probably thyroid issues. Wouldn’t you suspect because so many people we talk with they have adrenal issues with them on top of that there is a thyroid problem. Like maybe elevated reverse T3, whether you’ve got that blank bullet going on or they just got a low free T3 or like you and I’ve chatted about with adrenals, you’ve got the conversion process that happens where you take the inactive T4 hormone, you convert that to active T3.That conversion process gets messed up if you’ve got chronic stress. And chronic stress as you mentioned, could be gut infections, it could be emotional stress, could be chemical, heavy metals. It could be circadian rhythm stress if you’re working third shift, for example. That could be enough to change this whole cascade. Wouldn’t you say?

Dr. Justin Marchegiani: Oh, yeah. Hundred percent. I mean, again, all of those things can be intimately connected. The first we look at is thyroid because thyroid hormone has a major effect on our metabolism. And our metabolism is the sum of all chemical reactions in the body. And our metabolism is pH driven, right? So if our pH becomes too alkaline or too acidic, like you know blood pH, which exists in a very fine-tune range, right around 7.35+ or -1/10 of point there. And if that pH shifts up or down, that can affect how all of our enzymes in our bodywork. So that can affect temperature and there’s things like—uh like a diabetic coma, right? Where blood sugar can go to he— or too low typically. If someone’s type I dependent and they don’t have insulin, they don’t get sugar into their cell, which can create ketoacidosis. And that can really, really drop that pH and that put you into a coma. So our pH is very driven and has a major effect on our metabolism, so, totally.

Evan Brand: So let’s hit on—let’s hit on the thyroid peace. Now autoimmunity is something we talk about so much. Would you say a common symptom of someone with Hashimoto’s, for example, could be low body temperature or possibly even a fluctuating. Maybe their low body temperature if they’re a bit underperforming but then couldn’t they just bounce right back and get actually hot if they bump into hyperthyroid. If they’re in the Hashimoto’s state, and things are still fluctuating.

Dr. Justin Marchegiani:  Yeah. So, if you’re having Hashimoto’s and your immune systems constantly attacking your thyroid, your thyroid hormone can spill.

Evan Brand: Right.

Dr. Justin Marchegiani: Coz every time it’s attacked, hormone spills out. Eventually those follicles run dry and you’re not gonna quite have that hyper kind of symptoms. So in an acute attack, hyper symptoms may be increased temperature are common, right? You can have like PVC’s periventricular contractions. Uh—you can have, you know, kinda this—kinda heart palpitations. Your heart’s kinda beating erratic and hard, uh—anxiety, night sweats, irritability. These are all hyper thyroid symptoms. You feel warming, right? You feel excessive warmth or temperature. But then, in a chronic state, that will eventually lead to a hypothyroid kind of environment, where your body temperature just gets very low.

Evan Brand: So someone has had Hashimoto’s for quite some time, let’s say there’s been a pretty significant tissue destruction, you would say someone will not end up being hyper long-term with Hashimoto’s. It’d probably be hypo long-term.

Dr. Justin Marchegiani: Yeah. I mean you can—hyper feels very similar. Hyperthyroid Grave’s feels very similar to a hypothyroid autoimmune attack. The difference is with hyper, typically, there’s a specific antibodies or immunoglobulin compounds that come back. So with Grave’s, you’re seeing TSI immunoglobulins or you’re seeing thyroid TSH receptor site antibodies. So that’s what’s typically common in Grave’s. And when those things are high, it’s accelerating the thyroid hormone to produce excessive amounts of thyroid hormone. So there’s like a production stimulation where with the autoimmune attack, from like thyroglobulin antibodies or TPO antibodies is it’s more the spilling of a thyroid hormone out of the thyroid. It’s spilling out where the antibody attack from Grave’s, it’s stimulating the thyroid to produce more.

Evan Brand: Exactly.

Dr. Justin Marchegiani: With Hashimoto’s, you’re not getting the stimulation. You’re more or less getting that spilling effect, which eventually, you know, will run dry.

Evan Brand: Got it. Got it.  Okay. So we hit the autoimmune piece. What else would go on thyroid-wise that will be an issue with temperature regulation?

Dr. Justin Marchegiani:  Well, again, there’s also certain nutrients that have a major effect on thyroid uh—conversions. So we know things like selenium are super important for thyroid conversion. So someone may have decent thyroid levels from a T4 perspective, uh— but they may not have that activation, right? They may not have that conversion uhm— that’s so important.

Evan Brand: So could it just be the lack of trace nutrients, trace mineral selenium, zinc— things like that activators.

Dr. Justin Marchegiani:  So here, we are live on Facebook now, too with the low body temperature podcast. So getting back onto our common thread. Yeah, micronutrients like selenium are gonna be important for thyroid conversion. It’s a five—the enzyme that converts T4 to T3 inactive thyroid hormone to active thyroid hormone is a 5 deiodinase enzyme. It’s also important with glutathione and detoxification. So, yeah, that’s totally uh— important micronutrient that will affect thyroid activations. So when we look at thyroid function, we’re looking at are there blood sugar fluctuations? Are you eating grains or foods that are gonna cause that thyroid antibody attack that could cause the hormones to spill out and eventually deplete the hormones? Your thyroid follicles carry about four months of thyroid hormone. So again, if you have a chronic Hashimoto attack, where the thyroid hormone’s spilling out faster than you can synthesize and make more, then you’re going to definitely get to that depletion state where you’re gonna go hypo from a temperature standpoint. You’re gonna go almost hypothermic. That temperature will drop below that 97.8 – 98.2 armpit temperature wise or 98.2 to 98.6 and I’ll put a handout down below to my uh— metabolic temperature handout. So people can actually track their temperatures and it’s basically a graph of three different lines. And then the top brackets where you want your temperature to be through which ranges 97.8 – 98.6 We want to be checking off daily that your temps are in this bracket not the bottom or the very bottom.

Evan Brand: Got it. Okay. So what else? Should we talk about the nutrients next?

Dr. Justin Marchegiani: Should we talk about the nutrients, right? Vitamin A, we talked about uh— zinc, copper, selenium, magnesium very important nutrients for thyroid conversion. Now if you’re eating a whole food diet, you’re gonna be typically pretty good. If you’re having enough HCl and enzymes, you’re gonna be good as well because we need those type of compounds to be able to ionize the minerals. So it’s the diet component. It’s making sure we have the ability to break down the foods in our diet that are nutrient dense. Uhm— number three is making sure our stress response is okay because stress hormones will affect thyroid conversion. Cortisol being hyper— very high— will affect thyroid T4 to T3 conversion that inactive to active thyroid hormone. Also, if cortisol is too lo from chronic stress. So there’s this, kinda Goldilocks effect that we see here with thyroid hormone kinda need it to be not too high, but not too low to have optimal conversion. Does that makes sense?

Evan Brand: Yeah. It does. Well said. Let me mention about the gut, too, coz you just hit on the fact that you’ve got to have absorption. So even if the diet’s good, which many people listening to us, they probably already dialed in like a Paleo template but they could still have this symptom. You may want to check for infections. Coz like Justin and I talk about almost every week at some level, there could be an H. pylori, bacteria, yeast, fungus, something going on in the gut that’s stealing your nutrients or preventing you from optimally digesting. And then that issue is compounded, if you’ve been taking any type of anti-acid where acid blocking medication something simple as Tom’s or something more strong like a prior was it Prilosec or Zantac.

Dr. Justin Marchegiani: Yeah. So, yeah. Totally.

Evan Brand: Keep that in mind. If you’re looking at your medication list and that includes acid blockers and you have cold body temperatures, it’s probably cause you’re not digesting your foods therefore the thyroid is not getting fed the nutrients it needs.

Dr. Justin Marchegiani:  Totally. And also a lot of medications could affect your mitochondria. Just Google antibiotics and mitochondrial function, you’ll find that antibiotics can negatively impact mitochondrial function. And you’ll also find that other medications can impact the mitochondria. And the mitochondria is like the little powerhouse of your cell where it generates a lot of ATP, which is that currency of energy in which your body runs. So that’s really important and also an important nutrient call carnitine really helps that mitochondria utilize fat for energy, generate ATP out of that good fat, you know, it’s called uh—beta oxidation where you’re generating energy from fat. And carnitine is an important nutrient primarily made from methionine and lysine. Now, I did a video call why vegan and vegetarian diets can make you fat? Now—no—don’t make you fat. But you know, why they the can—meaning it’s not a hundred percent. But if you’re insulin resistant and you’re doing it the wrong way, where you’re emphasizing maybe too much carbohydrates, not enough protein and more gut irritating foods, yeah, it can definitely predispose people that have an inflamed guts and work more on the insulin resistance side to gain weight. And one of the big things is that when you eat certain animal rich amino acids, there are some plant ones as well, you activate the cells in the brain that are called—hold on, one __my notes—uh—tenocytes. And these tenocytes are receptor sites in the brain in the third ventricle area of the brain. And there’s a direct blood flow between them and the hypothalamus. These tenocytes, one, they sense satiety but the big thing that senses satiety for them is arginine and lysine which are really high in animal-based foods. So these amino acids really get that sense of satiation so that means you’re one, gonna have appetite regulation. Coz when you actually start feeling full, you tend to not eat all the crap, right?

Evan Brand: Yup.

Dr. Justin Marchegiani: So the more you can keep your cravings in check, the more you eat healthier foods because you got control over your biochemistry. You’re not reacting. You’re acting based on what you know you need to be healthy. But those amino acids are primarily gonna be higher in animal-based foods especially lysine as well.

Evan Brand: Yeah. Well said.  So in a roundabout way, if you are a vegetarian or a vegan and you’ve got low body temperature, it could just be something as simple as a carnitine deficiency. I mean you could probably get a little bit in beans maybe—

Dr. Justin Marchegiani:  A little bit in beans, a little bit in almonds, a little bit in plums and avocados, for sure.

Evan Brand: But even then, once we talked like—we talked all the time, digestion of those foods is probably not very good and the concentration of those is gonna be much less as opposed to a grass-fed beef.

Dr. Justin Marchegiani: Yeah. In my video, I talked about, you know, if you are a smart vegan where you’re not emphasizing a lot of the grains, you’re doing safer starches, you’re getting lots of fats from avocado, olive oil, coconut oil, you’re supplementing DHEA in the form of algae, right? And if you’re getting B12 uh—supplementation and you’re getting a good multi- in there and you’re getting lots of— you’re getting some protein supplementation in there, maybe from pea or hemp, right? You may be okay on a vegan-vegetarian diet, but it’s just— it’s still less than optimal just because of the fact that you gotta go through such extreme lengths to get high-quality protein sources without all the carbohydrate. Coz vegetarian-vegan diet’s typically are packed with 60 to 80% carbohydrates for that 20 to 25% of protein you get.

Evan Brand: Yup.  Well said. You hit on the mitochondria, too. We should take  that a bit further and talk about more toxins. You hit on antibiotics, some mitochondrial issues there. Makes perfect sense. We work with people all the time where they say, “Oh Justin or Evan, as soon as I took a round of antibiotics, all of a sudden things went bad.” And it could be temperature –temperature issues, it could be sleep problems, it could be gut issues, digestive problems. And so also with mitochondrial issues, we’ve got toxins. So if you’re not using 100% organic, that’s an issue because glyphosate and these other pesticides and herbicides, fungicides and insecticides— they all compound with each other. So it’s not that one chemical by itself will kill you, but if you get a little bit of glyphosate from your non-organic berries, you combine that with a little bit of conventional vegetables coz you did a salad at a restaurant, you combine that with in antibiotics that you’re getting from meat. If it’s not labeled “no antibiotics” you stock all those upon each other, you’ve got some bad mitochondrial problems here that you need to fix. And we can measure the—

Dr. Justin Marchegiani: Yeah. The enzymes that are needed to help move those gears that  kinda crank around that mitochondrial Krebs cycle and then flow in so the beta oxidation process. Uhm— you need certain nutrients. You need B vitamins, you need magnesium, you need zinc, the healthy levels of amino acids. You also don’t need all the toxins— the aluminum, the pesticides, the glyphosate. So those things can kinda gunk up the gears of that metabolic machinery. So it’s not only what those gears need to keep it lubricated, but what it is we don’t need to put in that will prevent those gears moving. So it’s a combination of avoiding certain things, right? And again, the medications are a double-edged sword. I’m not saying don’t use them. I’m saying just really make sure they’re— they are prescribed specifically for what you need. And it’s the last case kind of thing with antibiotics. We really want to go to herbs and botanical nutrients over antibiotics. They may have a time or place, but we want to use it only when we’ve exhausted other options.

Evan Brand: Yeah. Well said. And you and I were talking off air, we can quantify a lot of this stuff, too. So you’re talking about measuring your temperature. We can quantify what’s going on in the gut, right? We can test the gut, we can test the thyroid with—with blood using functional reference ranges and using functional numbers that conventional doctors don’t use. They’re only going to detect disease. We’re going to detect the issues before disease occurs. We’re gonna look into the gut so we could test you for infections. We could test the adrenals, look at your free cortisol rhythm so the uh— HPA axis, the hypothalamus, pituitary adrenal axis, you hear us talk about, you know, that is a factor in all of this. If your brain is not connecting the signal to the adrenals and adrenal to the thyroid, that whole system gets often chronic stress. And it’s up to us to figure out when we talk about stress what’s in that bucket. Is it just your job, your bad boss, your relationship, the divorce you’re going through? Is it that stuff only or is that stuff plus chemicals in the diet, plus nutrient deficiencies, plus infections, plus not having enough quality meat in the diet.  You see how these things can all add up.

Dr. Justin Marchegiani: Totally. And just to kinda look at the thyroid component again, there’s dysregulation up top where the TSH is either high extreme, higher extreme, low. Now it can be extremely low because you’re on thyroid hormone and the body needs more thyroid hormone. The body is sense— sensing more thyroid hormone in the brain, but there’s less than the actual tissues. So that you’re keeping the thyroid hormone higher, but that’s keeping the TSH low. That’s step one. The TSH may be low because of HPAT access dysregulation. That hypothalamus pituitary and that adrenal thyroid axis. There’s some kinda short-circuits happening in there because of the stress— the emotional stress, because of the physical stress, because of the chemical stressors. And we have to address those while we support the nutrients to get this hardwire back on track. We can also have low T4 levels. Coz if T4 is low, we’re gonna have low T3 over here. So we got to make sure the nutrients for T4 in there like I mentioned before the vitamin A, the zinc , the copper, magnesium, selenium, uhm— amino acids, tyrosine and potentially iodine. As long as we know that there’s not uh— autoimmune attack that’s the lease active going on. And then number three, after that, we let see how the T4 to T3 conversion is. If T4 is good, how does T3 conversion look? Is it this big drop off? Or also is there a very high amount of reverse T3 because of that stress? All those can make a big difference. And then one person ask here—James asks, “Well, is hypothyroid and hyperthyroid hypo and hyper kind of the same for treatment?” Yes and no. With hyperthyroid from a TSI thyroid stimulating immunoglobulin or TSH receptor antibody attack, we’re more concerned about coz it tends to be more chronically high which can increase the chance of a thyroid storm and then potentially a stroke. So we take that very seriously. We refer that patient out to their medical doctor uh—for monitoring. We don’t want—we wanna make sure there’s not a stroke going on. But typically, the treatment will be, you know, PTU. Uhm—basically  uh—propylthiouracil or methimazole. Things to basically block iodine uptake to make thyroid hormone. Or though— you know, typically, go to a thyroid radioactive thyroid kind of ablation or even a thyroidectomy. I’ve had patients where we’ve been able to avoid those because we give nutrients to help modulate the thyroid response and modulate the autoimmune response like carnitine, like blue flag, like lemon balm, melissa uhm—into certain adaptogens. They could also help kinda dampen that response. There are some protocols that even show higher amounts of iodine can block that sodium uhm— iodine’s import that transfers iodine into the thyroid. So there’s a couple of different protocols you can use to help. And of course, all of the diet and lifestyle things are the same. But we take the Grave’s autoimmune attack a little bit more seriously just because of the repercussions of it not being treated appropriately, what will happen, we really want to sidestep those.

Evan Brand: Yup. Well said. So get the TPO antibodies checked. Get your eTG antibodies checked, you talk about the TSI. Now, have you seen where TPO TG would be high at the same time as TSI? Where it’s gonna look like Hashimoto’s and Grave’s at the same time?

Dr. Justin Marchegiani: It could. I’ve seen it before.  Yeah. It definitely can. So get—we’re  gonna really get patients on an autoimmune protocol to help lower any autoimmune attack from the food, from the gluten, from the leaky gut. And we’ll also work on blood sugar stability coz high and low blood sugar fluctuations have a major effect on the immune system.

Evan Brand: Yup.

Dr. Justin Marchegiani:  Now another person asked here, the reason why you know I’m such a huge fan of how we do our podcast is coz it’s literally on the go and we’re infusing questions from people on YouTube here right into the conversations. So it’s like—remember those books you read when you’re like a kid and you read it and it’s like, “Oh, if you want the character to do this, turn to this page. If you want the character to do this, turn to this page.”  You can totally change how the book goes.

Evan Brand: Yup.

Dr. Justin Marchegiani: Well, it’s kind how our podcast are. So interjecting here uhm—, Gerald asked, “What about T3? How does T3 work?”  Well number one, T3 can just help support low T3 levels. And if there’s some kind of conversion issue, that can kinda biased time to fix the conversion aspect, number one. Number two, giving that T3 in the Wilson protocol uhm— that can have some effect on clearing out the receptor sites. So that now the T3 works better and binds better uhm— in the future. You can do that by starting low and then tapering up, holding it and then tapering it back down. In the Wilson protocol, Dr. Dennis Wilson does that with time-released T3. But we do a glandular’s in it. That can still be helpful as well. We’re using that as a way of clearing out the receptor site but were also not, you know, thinking that that’s gonna be the only issue. We’re also banking that there’s other things that we’re gonna be fixing that will allow it to be a long-term solution, right?

Evan Brand: Got it. So you’re saying the thyroid glandular’s can be used for low—a low  T3 situation.  That’s the fix that’s going to get you better enough to keep moving the needle in other departments.

Dr. Justin Marchegiani: Correct. Like in my line, we have Thyro Balance which is a—a really glandular uhm—nutrient thyroid support from a glandular perspective. And then we have that we have Thyro Replete which is nutrients for the conversion. So there’s some herbs that help with conversion like coleus forskohlii and ginseng and then we have the nutrients for conversion that I mentioned—the vitamin A, magnesium, copper, zincs, selenium—all of those—and tyrosine’s. We wanna make sure all those are in there. Uhm so we hit it from all angles. I mean if we knew exactly what that missing like nutrient component was, we could hit it more practically. But it’s too difficult to do that.

Evan Brand: Right.

Dr. Justin Marchegiani: You’re better off using multiple methods to hit it. That way the patient can get better faster.

Evan Brand: Agreed. And you mention the adaptogens. I’m so glad you did. We use those all the time. I take them every day in some shape or form, whether it’s ashwaganda, holy basil, shoshandra. There are so many options and people ask, “Well, can I just take a bunch of adaptogens and fix myself?” Uhm— it doesn’t work like that. You just want to use them as one piece of your toolbox. You still want to be getting to the root cause. So adaptogens are life-changing but if there’s root causes, you can take all the adaptogens in the world and it won’t fix you.

Dr. Justin Marchegiani: I’m gonna take my ashwaganda right now—

Evan Brand: Perfect.

Dr. Justin Marchegiani: A little bit of immune support. But I mean, like yeah, if you’re doing okay and you’re like, “Hey, Dr. J and Evan talked about some ashwaganda and some of these nutrients. I want to try it out.” Fine, go ahead.  But if you’re actively having issues that are you know, the symptoms that we mention here whether it’s on the hyper or hypo side, you really want to get someone on board to help guide you because it’s never just one magic bullet. It is—it’s a whole bunch of things that we’re doing together. And the more chronic it is, the more you have a you know, that momentum working against you. You got overcome that inertia to stop that— that snowball effect and start pushing it back uphill. So, yeah, if you’re in pretty good shape, fine you know just try some of these things. But if you’re in not so good shape, you want to reach out, for sure.

Evan Brand: Yep. Cool. Oh, we got time for one more question. Uh James said, “It’s not a thyroid question.” He’s taking an antibiotic for root canal this week. “Will this affect the result of organic acids test and stool test if he collects the samples while antibiotics are still in the system?”

Dr. Justin Marchegiani: I mean if we’re doing some of the genetic base testing, it shouldn’t have an effect on it. If we’re doing a stool base to antigen-based testing, then it would.

Evan Brand: Right.

Dr. Justin Marchegiani: So you should be okay but we’re doing the G.I. map which is you know, what my go-to is. It should be okay according to the lab. I try to avoid it— doing it. So I would say in a perfect world, if it’s not gonna delay your treatment, I would say get to the antibiotics give it like a day or two to let it wash out and then do it. But if uhm— timing doesn’t work out, just do it, get done.

Evan Brand: I would also look at Mercola root canals and read about those. I mean maybe you’re too far down the rabbit hole and you can’t avoid the root canal. But you know there are some other options you may have available if you’ve got a good biological Dennis maybe will sit down with you and say, “Okay, root canal’s option A but maybe there’s a option B C you could look at too because we’ve had a lot of people to come to us with infected root canals and maybe Jessica can speak on this a bit. But I’ve seen it as a big needle mover for people.

Dr. Justin Marchegiani: Yeah. There’s a book by Ramiel Nagel that talks all about root canals. It is highly recommended. You take a look at it. Uh— fat-soluble nutrients, vitamin A, vitamin K are very helpful. Uh—oil pulling that kinda help extract any toxins that may be in there and you don’t want a root canal you want to get the tooth pulled out. Uhm— you want to get an implant put in using biologically appropriate material. You don’t want the gangrenous tissue still in the system without the blood flow. And the immune response to be able to get it is just a harboring place for a whole bunch of bacteria and viruses to hang out.

Evan Brand: Right. Yeah. Well said. So James, look into that. Maybe it’s not too late. Uh—hopefully, you’ve got some other options you can pursue it’d be much— much safer and much healthier in the long term. That way, you don’t have a hidden dental infection. There’s a guy named, Simon Yu that you and I should reach out and interview. He’s over in St. Louis he talks a lot about hidden dental infections. I think that’d be a good show.

Dr. Justin Marchegiani: Okay. Absolutely. Hundred percent. So couple of things we wanna talk about. Oh, also carbohydrate, I think is important. Again, my bias is towards a lower carbohydrate template—Paleo template. And again, I hate the word “diet” because it assumes something is temporary and it assumes that it is fixed; where a template gives us flexibility and modification and may change day to day. It may change uh—meal to meal. I tend to be very lower carbohydrate my first two meals of the day and then after that, I may increase in carbohydrate at nights uhm—you know a bit of the starchy based. So I’m very strict during the day. It’s high-quality. It’s— set—it’s 60 to 70% fats, the only carbohydrates are vegetables and then good proteins and then I go higher at night. On the carbohydrates side, maybe a little bit of sweet potatoes and some butter and cinnamon or maybe I have a—some dark chocolate or have couple more berries than I normally would. So there’s that component. So I always go lower carbohydrate to start because so many people are insulin resistant just because of the fact that we eat too much carbohydrate and were inflamed. So I always go lower carbohydrate to start and then typically, patient will do be better and will feel better because insulin resistance can affect T4 to T3 thyroid conversion, which can cause lower temperature. Now, in the double edge side of the fence, if people go too low insulin, they may also get poor thyroid conversion as well. So just like I mentioned cortisol has a major effect on thyroid conversion. Well, guess what? Insulin has a major effect on thyroid conversion. Type I diabetics— guess what? With low insulin levels coz of the autoimmune attack to the beta cells of the pancreas, they have low body temperature. So if you go too low carbohydrate, and this is for certain individuals not everyone, I know people are gonna be like, “But I’m low carbohydrate and I felt great and it reverse my low temperature.” I get it. Again, there are exceptions to every rule. There are tall Chinese people that play basketball even though they are more shorter in the population. There are exceptions to everything, okay? We got to get that in. So yes, there are some people that a low carbohydrate diet, the majority I would say would help partly because our consumption of refined carbohydrate and sugar is higher, but there are some people when they’re chronically load, they may increase that carbohydrate just a bit. And that ups the insulin a little bit which then helps that thyroid conversion. They’re like, “ Dude, my hair started to grow back better, my temperature’s better, my energy is better.” Boom! You at least now figure it out for you. So exceptions to every rule, figure it out. And uhm—if you feel great going low-carb, great, keep it there, hang out. But if you start getting some of those hypo temperature symptoms, then we’ll just ratcheted up a little bit.  And I primarily ratcheted up starting at night.

Evan Brand: Yup.

Dr. Justin Marchegiani: They’ll still get the benefit of keeping it lower carb during the day.

Evan Brand: Well said. I mean that’s me in a nutshell. I went very, very, very low-carb ketogenic, I guarantee. I was probably ketogenic most of the time and then I started to get cold and so I added in some starch with dinner and all of a sudden my body temperature’s perfect now. I feel good. So uh—if I go too low-carb again, it may come back or if there’s a huge piece of stress on my plate, the low body temperature may come back. But for now, I’ve been able to reverse this and been able to clear out all the infections with your help in terms of protocol a couple of years ago getting rid of all my gut bugs, plus supporting adrenals, getting the diet dialed in, getting my sleep improved, blacking out my room. All of those things are still important. So I hope this has been helpful. I gotta run. You’ve gotta run, too. Uhm—or are there any last questions that we could answer? I closed out the chat window. Uh there’s just one thing I want to say is it’s not about being higher carb or lower carb, have a –have a foundational template which you— which you go back to and then you can customize it. And then if you increase carbs, you can still get some of the benefits by having that first 20 hours of your meals relatively lower carb, higher fat, moderate protein and those last four hours you pop up a little bit and so you can still get some of those benefits. If you’re like, “Oh, I feel better with higher carbs.” You can still get the benefits of the first 20 hours of your day kinda in that ketogenic state and then pop up the carbohydrates later. So it’s not an either or thing. We can kinda straddle the fence but we want to customize it. I don’t give a crap if—if low-carb is your missing link and being low-carb all the time helps you, that’s what we’re gonna do. If being low-carb and a little more high carbohydrate helps you out, I don’t care. I’m all about the results and not about what tool I have to use to get the job done.

Evan Brand: Yup. Well said. For me that looks like the breakfast like a pastured sausage, maybe a handful of macadamias, maybe a handful of organic blueberries. Lunch—I  probably do some leftover steak and veggies like a big thing of broccoli with some butter. Dinner— that’s when I may do some type of pastured meat, a little bit of some veggies and then starch, so it could be a medium-size baked sweet potato, butter, cinnamon. That’s all it takes and I feel good. So just to kind of give people an idea what is that look like. That’s what it looks like.

Dr. Justin Marchegiani: Totally. That’s great. And a couple of questions here. Uh— Stephanie talks about menopausal women with lower estrogen and a low estradiol vaginal tablets. Well, this is interesting because typically low estrogen can cause hot flashes. And why does that cause hot flashes? Because typically the FSH and the LH starts to rise in the pituitary which is that signaling hormone trying to yell to the ovaries to make more progesterone and estrogen. So when LH and FSH primarily FSH goes high, that can create some vasodilation effects and create the hot flashes. So by giving a little bit of thyroid—giving a little bit of uhm— female hormone support, we can drop down that FSH then we can also modulate the receptor sites with some herbs as well to help with how flashes. Whether we use maca, or  we use dong quia, or black cohosh or raspberry root, or shepherds purse. There’s different nutrients or herbs we can do to help modulate that. So again, you could still have hypo, low thyroid issues, but have menopausal issues because of the low estrogens, which could drive the hot flashes up. So it’s kind of a conundrum. The hot flashes may—may overshadow this low thyroid thing over here. So as we get the female hormones fixed, you may notice the low thyroid comes back later on because it’s just not a secondary issue and the primary issue is the menopause. Once that’s ruled out, now this one comes to the surface.

Evan Brand: Got it. Well said.  We should probably do a whole show just on low estrogen if we haven’t.

Dr. Justin Marchegiani: I think that’d be great. I mean, I see estrogen dominance is a big problem.

Evan Brand: Right.

Dr. Justin Marchegiani: Where estrogen –the ratio of estrogen is higher than progesterone, right? So progesterone should be like this 25 to 125 times more than estrogen. But if that ratio starts to creep up where estrogen gets higher, that’s estrogen dominance. The problem is a lot of people, though, where that ratio—they’re estrogen dominant, progesterone’s slow but estrogen is also low. So they get this estrogen dominant, but also low estrogen sums at the same time. So it’s kinda like this conundrum. It’s like this little tug of war that’s happening there.

Evan Brand: Wow. Put it on this to do list. It sounds like it’s gonna be a fun one for us to dive into more. And I’ve probably got some stuff to learn from you on that topic as well.

Dr. Justin Marchegiani: I think it’s great. Well any last questions, comments, or concerns, Evan?

Evan Brand: No. I think this has been good. People, you got to get the testing run because if you don’t test, you’ve guessed. So if you’re trying to figure this out on your own, even if you’re not working with Justin or myself, then get the test run. Find a functional medicine practitioner they can take care of you. We are accepting new clients, so if you do need help, feel free to reach out justin health.com evanbrand.com We run these labs on all of our clients because it’s the foundation. We’ve got to have the data. We’ve gotta have the puzzle pieces on the table; otherwise, you can’t move the needle. We could throw a bunch of random stuff at you might help, can’t hurt, but we want to get you better. There’s a systemic process that we do step by step by step to take you through this. So happy to help. Reach out if you got questions and thanks for tuning.

Dr. Justin Marchegiani: Oh! One last thing, man. I forgot to add.  This is so important. Low calories.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Just not eating enough calories will cause low body temperature. It’s shown to cause a low level T3. Now this is important because if your diet is 25% crap Ola and let’s say you’re eating 2000 calories a day and then we switch you over— we switch you over to a uh— autoimmune kinda Paleo template, but you’re only able to—to—to switch over 75% of your diet because you don’t—you don’t have enough you—you can’t replace all the crap that you’re eating with the good stuff, right?

Evan Brand: Right.

Dr. Justin Marchegiani: Because if you’re eating a whole bunch of crappy carbohydrates and stuff and then you replace it with a whole bunch of really good vegetables or lower sugar foods, well guess what? You’re probably didn’t replace the calorie amount either. So now you got this 25% calorie deficiency. So now instead of having 2000 calories, right? Now you’re having 1500 calories and maybe metabolically you need 2000 calories. Now you’re 500 calories in the hole which means your 500 calories deficient of various nutrients. So now your metabolism goes low coz there’s less fuel. That’s important. I see a lot. So you gotta  work with someone that really can make sure you’re exchanging the foods and you’re getting enough calories as well. Coz calories equal nutrition. if you’re eating real foods.

Evan Brand: I’m glad you mentioned that. That’s such a simple but common issue. If you’re going AIP, you are going Paleo, you’re eating real foods, you could have an entire plate full of broccoli and it may only be 50 calories.

Dr. Justin Marchegiani: Exactly.

Evan Brand: Yeah. Dude, great job. Way to kill it.

Dr. Justin Marchegiani: And of course, the infections like you mentioned can really suck down the energy. Of course, acute infection, you know, you’re causing a fever, right? Because the immune system’s trying to up regulate itself because a lot of the bacteria and crap there uhm—they’re like—they’re mesophilic. They—they thrive in a medium temperature. So when you go a little bit higher, you can actually kill them off with a higher temperature. But these chronic bugs can really deplete the energy the body and create this kinda lower temperatures as well. For sure.

Evan Brand: Yeah. And I went—I went to low-calorie for a period of time, not intentionally, not on purpose. It just happened. I was eating meats, I was eating veggies and  I track my calories for a few days and I was eating m—and my activity level  and all that. I was probably 4 to 600 calories deficient. So just added in an extra tablespoon of butter here and there, half of an avocado here and there, handful of nuts and seeds. And I was right back up to where I needed to be.

Dr. Justin Marchegiani: Like here’s a seesaw right?

Evan Brand: Yup.

Dr. Justin Marchegiani: So if like carbohydrate is here, if carbs go lower— this is fat over here. The fats have to go up.

Evan Brand: Yup.

Dr. Justin Marchegiani: If you keep the fats here, you keep the fats on—on this side low, and drop the carbohydrates, that’s where the problem happens. The fats also have to go up. That’s the biggest issue. Proteins typically stay in the middle. Typically, proteins only go up if you’re doing a whole bunch of protein powders because proteins and fats are intimately connected. Uh so if you’re eating real whole foods, you know, it’s hard to get just proteins in whole foods, unless you’re doing maybe like venison or rabbit or like boneless chicken breast. But if you’re eating full fat foods, you’re gonna get fat. And then if you’re adding fats to your vegetables, you’re gonna get extra fat without the protein there as well.

Evan Brand: Yeah.

Dr. Justin Marchegiani: So keep that at the back of your head.

Evan Brand: Perfect.

Dr. Justin Marchegiani: Anyone listening here, give us comments below. Give us some shares. Give us some likes. We want to hear thoughts in the comment section. If you’re listening to us on iTunes, that’s great. Click below and subscribe to our YouTube channel. You can see Evan and I’s mugs going back and forth in our little combos here. And then you can give us some comments below here on YouTube. We love the see the feedback. And Evan, hey man, you have a great day. We’ll talk soon.

Evan Brand: Take care.

Dr. Justin Marchegiani: Take care. Bye.

Evan Brand: Bye.









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