9 Ways to Fix Your Gut Flora

9 Ways To Fix Gut Flora

By Dr. Justin Marchegiani

What is Your ‘Gut Flora’?

There is a whole community–a whole universeliving within our intestinal tract. Roughly two pounds of microbes live in and on our bodies; the vast majority of these are located in our gut. With this many guests setting up camp inside of us, we must take precautions, just as we would if we were hosting guests in our homes, to ensure we are only inviting good company.

How Your Gut Flora Affects Your Health

How Your Gut Flora Affects Your Health

Our gut flora is responsible for more than you might realize. It can cause cravings, impact our mood, and affect allergies and food intolerances. By keeping our gut bacteria balanced, we can control how fast our metabolism works, boost our energy, prevent disease, and extract more nutrients from our food. If you don’t have a healthy gut balance, your immune system will be severely compromised. Poor gut health is tied to many health issues and diseases, including:

  • Asthma and allergies
  • Autoimmune diseases (arthritis, IBS)
  • Cognitive decline (Alzheimer’s, dementia)
  • Fatigue and brain fog
  • Fungal overgrowth
  • Gluten sensitivity and other food allergies and intolerances
  • Infertility
  • Learning disabilities (ADHD)
  • Mood disorders (anxiety, depression): The human body has a “second brain” that we are just starting to learn about, located in the gut. Breakthroughs in science are being made on how the trillions of bacteria in our gut— the microbiome— communicate with the neurons in our gut lining. This effectively means the bacteria living inside of our intestines have an effect on our mood! Science is showing depression, anxiety, and other mood disorders are linked to the microbiome.
  • Parasitic infections
  • Small intestinal bacterial overgrowth (SIBO)
  • Type 1 diabetes

Click here if you are suffering from digestive issues to consult with a functional medicine doctor and start feeling better today!

Just as bad bacteria negatively affect your health, good bacteria have a positive influence on your health! Good gut flora assists in the following ways:

  • Gut flora is responsible for helping your body absorb and store nutrients, like vitamin B.
  • It produces vital nutrients. For example, your body doesn’t store or produce vitamin K, and the food you eat can only provide you with a little of what you need. Luckily, your gut flora produces the majority of the vitamin K you require, and since your body isn’t good at storing vitamin K, it’s crucial that your gut flora is always producing more for you!
  • Good bacteria keep the walls of your intestines strong and prevent you from developing leaky gut.
  • Balanced gut flora trains your immune cells to fight inflammation.
  • Good gut flora is energy-efficient.  Having an imbalanced (“bad”) gut flora means your body has to hold on to more food to get the same amount of energy, which causes more food to be stored as fat. On the flip side, if your gut flora is in good shape, you get maximal energy out of the food you eat and excrete what’s left over!

Nine Ways to Fix Your Gut


We’ve seen how gut flora is responsible for keeping us healthy or making us sick. How can we make our gut stronger? Here are 9 ways to fix your gut flora!

  1. Reduce or cut your sugar intake: Sugar is one of the bad bacteria’s favorite foods!
  2. Avoid inflammatory foods: Some studies have shown that fats and oils ruin your health, but this research studied diets comprised largely of refined vegetable oils, such as soybean oil. On the other hand, grass-fed butter, organic coconut oil, and extra-virgin olive oil have been shown to promote a healthy gut flora and aid in weight loss!
  3. Eat a variety of healthy foods: Eating a wide range of healthy foods ensures we have a diverse microbe population, which is very important!
  4. Eat vegetables with every meal: If you can fill half your plate with vegetables and plant-based foods, your good bacteria will have plenty of fiber and nutrition to feast on and use to boost your health!
  5. Choose organic: Not only are GMOs and toxic pesticides are bad for our microbiome, they also affect the soil they’re grown in, and our gut bacteria and the bacteria in the soil are related.
  6. Eat prebiotic rich food: Sweet potatoes, asparagus, and other prebiotic foods feed the good guys!
  7. Incorporate fermented foods into your diet: Sauerkraut, kombucha, kefir, and pickles are all delicious fermented foods.
  8. Take prebiotics and probiotics: The use of pre- and probiotics feed the good bacteria that keep your gut healthy.
  9. Take steps to lower your stress: Try meditation, yoga, a walk or a jog, or partaking in your favorite hobby to reduce your stress. Studies have shown that stress can actually negatively affect the composition of your gut flora!


The state of your gut is responsible for both your physical and mental health. Luckily, even if your gut is in bad shape, it is easily remedied by following the nine steps listed above. The good bacteria are always ready to move back in, all you have to do is provide them with the right environment.

Click here to consult with a functional medicine doctor for a personal plan to improve your gut flora!










Optimizing Your Functional Medicine Gut Program – Dr. J Live Podcast #164

In today’s video, Dr. Justin Marchegiani and Evan Brand discuss the topic of creating a functional medicine toolbox for your gut health. Learn about the natural ways to modify your diet, improve your digestion, and promote your overall gut health. Watch and listen as they reveal some of the tools in the trade.

Discover some protocols that help aid problems with gut fungus, yeast overgrowth and infection, gut bacteria issues and parasites in your digestive system. Learn about the different steps to take on how to ensure you’re taking the right path for better gut health. Also, stay tuned for more information about how to further catch some knowledge bombs from this functional medicine duo.Optimizing Your Functional Medicine Gut Program

In this episode, we cover:

03:30   Looking at the Food

04:23   Digestive Support

06:10   Silver in the Killing Phase

09:47   Probiotics and Antibiotic Therapy

13:48   Retest




Dr. Justin Marchegiani: Hey there! It’s Dr. Justin Marchegiani. Evan Brand, what’s going on, man? How are things?

Evan Brand: Happy Monday. Life is good. The sun’s gone, though. That’s sad. This time of the year just— gonna start that gray sky, so I’m kind of jealous. I’m sure it’s sunny in Texas right now.

Dr. Justin Marchegiani: It’s a little cloudy out here today, but I was actually in Lake Austin yesterday, water skiing. I got a new suit. It’s about a three-four millimeter kind of thickness suit, so it’s great. I go in the water, doing pretty good. I’ve got some little booties, too, that are neo-printed, and some gloves. The worst thing was the week before. I didn’t have the gloves— is you really— you know— ‘cause when you’re squeezing really hard, right? You kind of squeeze a lot of that blood out, right? You kind of like— you know, white knuckled, so to speak. You don’t have a lot of blood, so your hands get really cold with the air. So those new gloves made a huge difference

Evan Brand: Well, that’s awesome.

Dr. Justin Marchegiani: Yeah. How’re things going on with you?

Evan Brand: Things were good. You know, the baby’s running around and keeping me busy. She basically stole half of my lunch. She took all my carrots and almost stolen my peas, so that’s a lot of fun. You know, tweaking her diet. We just actually ran a GI Map on her. So, we’ll make it to Stool Test back. We’ll have to uhh— chat about what’s on there— Actually, no! I take that back. We got the results. She had Klebsiella on there. So, that’s pretty interesting.

Dr. Justin Marchegiani: Awesome, dude. I got my dog, Butter, here on the YouTube if you guys want to see her. Butter (kisses the dog). We love good healthy fats, that’s why we named her Butter. Uhm— but yeah— so, we’re in the same place. Aden’s doing really good, breastfeeding like crazy. He’s starting to sleep a little bit more, so we’re really excited about that. Really happy your daughter’s going good, too.

Evan Brand: What do you think about the Klebsiella with her? I mean, we’re using some herbs already. It’s like, at her age it makes you wonder. Did she pick up Klebsiella from somewhere? Did she have it? Was that passed through the placenta? I mean, it makes you wonder, her being that young.

Dr. Justin Marchegiani: Yeah. I mean, I would say off the bat, uhm— probably something from your wife? From you guys? And, I would utilize some probiotics and, maybe, one oil of Oregano Capsule a day, or something like that, or maybe decent to help. Keep it really low, though. [crosstalk] But use more probiotics. Anything else?

Evan Brand: We’re doing that tincture, I was telling you about, that’s got the uh—

Dr. Justin Marchegiani: Yeah.

Evan Brand: … I think it’s got the…

Dr. Justin Marchegiani: Yeah. [crosstalk] good one [silence]. That’s a great one. I like that.

Evan Brand: [inaudible] …worked it out. But anyhow— So, I’m sure we can do a whole podcast on that, but I figured, today, you and I should chat about creating a protocol. You know, if you’re trying to create a functional medicine toolbox for gut health, what would that look like? In that could involve things that could help with fungus, yeast, bacteria and parasites. We’ve hit on parasites and— you know, the influence of thyroid health and adrenal health. And we’ve hit on the link between parasites and leaky gut, and leaky gut and autoimmunity. So now, I feel like it’d be good for us to— you know, reveal some of the tools of the trade, which you’ve already mention one, which is the Oregano. So maybe let’s go into the order of operations first. Let’s talk about what comes first, like in this whole Functional Medicine approach. ‘Cause some people, they think probiotics are just be used anytime. And prebiotics, you can just throw them in. But really, there’s a— there’s a Science and there’s an order to herbs. Probiotics may not be the first thing that you should look at for an adult.   

Dr. Justin Marchegiani: Yeah, I know. I uh— I hundred percent agree with that. So, first things first is looking at the foods. If we have certain foods that are more offending and more inflammatory, that’s gonna potentially create the— the breeding ground on which bacteria can overgrow. There’s lots of different bacteria that can grow, so— I mean, we have more of our pathogenic type or Klebsiella, or Proteus, or Citrobacter, rella— or Morganella. These are our dysbiotic bacteria, not so good. They produce toxins in our body. They can eat up B vitamins. They can prevent our good bacteria from producing nutrition. So, of course, we want to make sure those things are under control. We will look at the foods first. Keep the inflammatory foods down. I think, potentially, in your daughter’s situation. They may have been some foods, they may have been slipping in some, like kind of pseudo-Paleo foods, potentially. [crosstalk] What food were you slipping in for her?

Evan Brand: Well, so we were doing the rice flour.

Dr. Justin Marchegiani: Rice flour? [crosstalk] Yep.

Evan Brand: Rice flour and also, there was some Tapioca starch and some of these like dried veggie snacks. They had Tapioca in there. So I’m thinking because, remember, I showed you that she had a small rash into her eye.

Dr. Justin Marchegiani: [inaudible] … improving?

Evan Brand: It’s gone.

Dr. Justin Marchegiani: And what food change did you make?

Evan Brand: The rice flour. We took it out.

Dr. Justin Marchegiani: I think there’s a gluten-sensitivity component there. So, I think [crosstalk] once you get that better, the gut bacteria will get better. So then, once that’s better, you know, looking at digestive support— so if they’re kiddos— I mean, you know, what can you do? So, typically, we’ll do like uhm— We’ll do some enzyme wafers that are really easy to chew and taste pretty good, for the little kiddos, they can eat.

Evan Brand: Is there any good brands?  ‘Cause I looked at some, and it looked like a lot of them had fructose in there, added.

Dr. Justin Marchegiani: Yeah. I mean, I like the Vitalzym’s chewables.

Evan Brand: Okay.

Dr. Justin Marchegiani: That’s a pretty good one. If they can swallow a pill, Then we’d  maybe have them do an HCL enzyme combo if they can get a pill. If they can’t, I’ll do a wafer.

Evan Brand: Ah— okay.

Dr. Justin Marchegiani: I would do that, and uhm— just really making sure they chew their food up really well. Uh— and then— you know, just cutting out the inflammatory food. So that would be my first two steps right there. And, I would even maybe do a smoothie for one meal a day and really just add some extra aminos, add some extra nutrients in there. So, it kind of gives her digestive system a break for at least one meal.

Evan Brand: That’s a genius idea. Did you know that the Vitalzym chewable has the DPP4 in there. So that would be great [crosstalk] if there is a cross-contamination issue going on.

Dr. Justin Marchegiani: Yeah. And that would be helpful. And the chewable— those taste pretty decent, too. Had a couple of kids— Yeah— fed them a couple dozen at least the last few years, do well with those. So, I like those, a lot. And then the next step is, you know, the Killing Phase. We kind of talked about, you know, the foods. We talked about enzyme support. Maybe we add them some gut-healing nutrients. Maybe we add them some collagen peptides. Maybe we add them some L-Glutamine to keep it really simple for the kiddos. Maybe we just put that in our morning shake. A couple of blueberries or berries, maybe a nice scoop of collagen or pea protein to keep it more hypoallergenic, maybe some coconut milk or MCT for some extra good fats, maybe we add some extra L-Glutamine— or like in my Lyme, we use like a GI Restore, some extra healing, soothing mucilaginous herbs, like Aloes, Slippery Elm, DGL Licorice; all very healthy and soothing. And then maybe we start the killing in a month or two later. We could start even with just like a teaspoon of Silver. Right? Twice a day, for your daughter who’s younger, right? Something very, very small. Maybe do one oil of Oregano Pearl, once a day. And over [crosstalk] Yeah.

Evan Brand: Talk more about the Silver. I mean, there’s antimicrobial benefits. I believe there’s antiparasitic benefits, possibly.

Dr. Justin Marchegiani: Yeah. I mean, Silver is proven to help with biofilms. They’re actually— My mom’s still a surgical nurse. She’s been a surgical nurse for like 45 years, and she has even— The last couple of years, they are actually adding in a Silver wrap. So, when they do like a total hip or a total knee, they’re actually wrapping the whole joint with this like Aluminum-foil-like thing, but it’s Silver. And they wrapped the joint before they closed it in that, uhm— to prevent, basically uhm— bac— antibiotic or just some bacteria coming from coming in.

Evan Brand: And that stays in?

Dr. Justin Marchegiani: No, it dissolves.

Evan Brand: Oh, it dissolves. [crosstalk] That’s cool.

Dr. Justin Marchegiani: It’s kind of like a cellophane thing that kind of dissolves. They do it— this one called Seprafilm. They put over like— you know, they do a surgery to prevent scar tissues. So, it’s similar to that. It’s kind of like a cellophane-thin kind of thing they wrap. Not sure of it’s up against the joint directly or if it’s around the fascia and the skin. I’m not sure about that. But it’s definitely enclosed around that joint for sure, to help with the biofilms and the resistant bacteria. Conventional medicine’s getting on board. And they have to, because they have a lot of problems with antibiotic-resistant bacteria. So, they kind of have to.

Evan Brand: Yeah, the C. diff, the MRSA. I’ve even heard of antifungal-resistant. Like this species of Candida diflucan and these other prescriptions aren’t working for even the yeast anymore. They’re— The yeast are evolving and getting too smart. Luckily, in our toolbox, we’re not using pharmaceuticals. We’re using herbs. And in this case, you know, if we’re talking about Candida, you mentioned the silver— We can use Silver against Candida, too. The Oregano can be against Candida. The garlic can be another good choice.

Dr. Justin Marchegiani: Yup, exactly. And there’s some liquid garlic options that we could always give her, too, as well. And then we could do some of the oil of Oregano. I like them ‘cause they’re smaller in pearl. So, like in my GI Clear 5 line, we have that, where we use the emulsified 75 percent Carvacrol extract, so it’s very potent. And it’s a pretty small uh— pearl, so typically, that’s easier to get down. And you can do that with the kiddo. You can do the Silver like I mentioned. And then we could always do some liquid garlic. So, those will be like kind of my options for kids that really had a hard time with pills, off the bat.

Evan Brand: Let’s chat about some statistics. I’ve seen kids as young as one, two, three, four years old, and they have infections, parasites, bacterial problems, a lot of Candida problems. ‘Cause the kids were unfortunately exposed to antibiotics early on, and now they’ve got a massive systemic yeast overgrowth.

Dr. Justin Marchegiani: Yeah. So, of course, anytime you have to use antibiotics. ‘Cause there may be sometimes— you know, you’re scared as a mom or dad, right? You’re like, “Oh my gosh! She’s getting out of control.” Number one, like have some things in your medicine cabinet like the Silver. You know, you could do even some ginger capsules is good, or some higher-dosed ginger tea if you can’t get that downward. It’s gonna be great. Of course, keeping the sugar out. But if we uhm— had to come at it with some probiotics during the killing, we can always add in some probiotics, some powder probiotics, and some saccharomyces boulardii. And we can put it in— in their drink, right? We can get them to have a nice little smoothie. We that in there. Or we could just mix it in, maybe their Kombucha or something. Or we could just come up with some kind of a drink they like and put it in there. That could be some really good options during the killing, and of course, we would do it after for at least one or two months.

Evan Brand: So, what do you think about Probiotics. I mean, some of the training I’ve seen and some of the protocols recommend probiotics during a killing phase and then some protocols don’t recommend probiotics. I mean, it— like—

Dr. Justin Marchegiani: It depends. There is some research showing that probiotics during antibiotic therapy can actually be beneficial. And again, most conventional antibiotic therapies don’t go longer than two weeks. So, I’m not that worried about it ‘cause we’re gonna be giving probiotics afterwards for at least two months. So, I’m not worried about if we want to go do it for two weeks. Do the probiotics while we do the antibiotics. I’m okay with it, especially if you have digestive issues. And let’s say the probiotics really helped and they’re soothing. Maybe they help keep you regular. Maybe you have a history of a lot of rebound yeast overgrowths ‘cause of post antibiotic therapy in the past, then I would. If you don’t, then I would just wait until afterwards. I don’t think you can go wrong if you do. Some people, they have histories of just antibiotics or let’s just say probiotics causing a lot of bloating and gas. And if that’s the case, and I’d probably wait. Yeah. May use some different strains. May use some coil or spore-like strains, or just doing it after the antibiotics. A lot of that flora’s gonna be knocked down. So, maybe the probiotics are more tolerable after that as well.

Evan Brand: And the same thing would apply for just straight herbs. If you were just doing straight herbal protocol. Sometimes, you’re gonna use probiotics during the killing. Sometimes, you’re not. Or you’re always using.

Dr. Justin Marchegiani: Uh— I only use probiotics during the killing, if we’re on a repeat protocol, like if we retested and we have new infections or other factions, just because I want to prevent any rebound overgrowth from happening

Evan Brand: Yeah.

Dr. Justin Marchegiani: Just kind of where you knock them out of the floor down. You even knocked the good stuff back, but we all know, if you do weeding in  the garden, you never have to go back and purposefully plant weeds, right? Weeds automatically grow.

Evan Brand: Yeah.

Dr. Justin Marchegiani: So, it’s kind of like that. We’re just kind of throwing down extra seeds during the process to take up the space that maybe those weeds would take. So, it’s kind of like a preventative thing, as well as— It can have benefits with inflammation and it can have benefits with regularity and motility as well.

Evan Brand: That’s good advise. And also, too. You and I see the Beta-glucuronidase enzyme on the Stool Test that we’re running. And if that enzyme is elevated, that could mean your recirculating your toxins and hormones and drugs and stuff like that. And one good way that we can get Beta-glucuronidase back down into normal range is probiotics. So, I love that you bring up [inaudible]—

Dr. Justin Marchegiani: Also— We can also use phages, too. Phages have some really good beneficial effects at knocking down that bacteria. And then, you know, depending on how regular you are, we can even slide in some activated charcoal, too. Some activated charcoal or some like Modified Citrus Pectin, trying to act like a little sponge and soak up a lot of the crap that are maybe sitting around your gut from all that bacteria.

Evan Brand: When would you make the call on that? Would that be like if you have a ton of bacterial infections plus parasites, they could try to treat five or six things at once? Like what if it was just H. pylori? Are you gonna hit the charcoal or not?

Dr. Justin Marchegiani: Depends on the person’s resilience. If they have a lot of fatigue, and they have a history of being more sensitive, or they have a history of lots of antibiotics and like they tell me like— you have like, in the past, antibiotics have really wiped me out, or I’m just really tired or if in fatigue, then maybe I would add in preventatively. I they’re pretty— like if energy’s pretty decent, then I would say, “Let’s wait and see.”

Evan Brand: Yep. .

Dr. Justin Marchegiani: …wait and see. But it’s something that’s always there, you know. Kind of undecked so to speak. So if we need to go, we can go to it. Of course, then one of the first things we can do is ginger tea, ‘cause ginger really helps the lymphatic systems. It’s very anti-inflammatory. Keeps things moving. It’s also a biofilm buster, too, so it helps— it actually helps the uhm— antibiotics work better. There were studies using Silver and ginger and they found that when they used the Silver and ginger, the antibiotics actually work better. So, I tell patients, if you need to use the antibiotic, use the ginger and Silver with it. And then, you can even add in the probiotics to prevent any rebound overgrowth. That way, you get the best of both worlds.

Evan Brand: Nice. That is awesome. And then, uh— I guess the last step in our toolbox— you know, we’re talking protocol, would be another test. Because, once you go through the— you talk us through the process, removing bad foods, replacing enzymes, repairing the gut…

Dr. Justin Marchegiani: Hmmn— hmmn.

Evan Brand: [inaudible] …infections re-inoculating probiotics. Then the last step in this whole protocol is the test itself. Retest and make sure [crosstalk] all the stuff we implemented was successful.

Dr. Justin Marchegiani: Hundred percent, yeah. So, if we have a specific infection we’re going after, we definitely want to put in their crosshairs, we want to aim at it. And then we want to go look to that scope again and make sure we actually hit it right. That’s kind of where that lab test retest would come in. Sometimes, if it’s just insignificant smaller amounts of yeast or smaller amounts of bacteria, and there’s not any major stuff— there’s no H. pylori, there’s no like significant bacterial overgrowth, there’s significant fungal overgrowth or any parasites, then we’ll just based it off of symptomatic relief?

Evan Brand: Yup.

Dr. Justin Marchegiani: Is there anything significant, then I want to make sure that we retest for sure.

Evan Brand: Yeah. It’s a great point. People ask it all the time. You know— “Should I retest?” “Do I really need to retest?” Maybe. But if you feel amazing, maybe we can assume. And your hair’s better, and your skin’s better, and your nails are better— like for me, I noticed when I thought my infections were gone because my weight loss stopped. Like, my weight stabilized, but I still did the retest, ‘caused I had the Giardia, Crypto, H. pylori, Pseudomonas, Candida— I had all of it. That was just too much for me to not spend the money on the retest.

Dr. Justin Marchegiani: Yeah. I wouldn’t give you the choice for those kinds of infections. But let’s say you had just a little bit of like yeast, or you had just a little bit of Citrobacter. It wasn’t off the charts and you didn’t have really awful symptoms, then I would probably say, “Hey, if you feel and improvement, that’s good.”

Evan Brand: Yeah.

Dr. Justin Marchegiani: I would say, “Let’s just keep you in the loop to retest once a year.”  

Evan Brand: So, people say, “Well, how would I know if I’m feeling good Dr. J? “ That would be things like what? If your brains working? Your…

Dr. Justin Marchegiani: Yes. [crosstalk] Everytime I— I chat with the patient, we always go over wins, challenges and corrections, diet, lifestyle, review, supplement review. So, of course, wins and challenges, what’s moving in the right direction at each appointment and what’s moving in the wrong direction. And of course, we have our baseline audit in the beginning. Patient comes in day one. Do patient exam. I got bloating. I had gas. I have diarrhea. We follow up. Make diet changes, lifestyle changes, supplement changes, how much better, what are our wins. “Oh, well. Bloating is down; 80 percent. Diarrhea is down; 90 percent.” And we continue to follow that all the way down. So each time we chat, we’re always checking in. We’re keeping our pulse on everything. I want to know exactly what we’re at, so to speak.

Evan Brand: Yep, well said. So, if those symptoms are still there, maybe the hair’s better but you still got the gas bloating. Well, could still be some yeast or bacteria going on there. Is that safe to say?

Dr. Justin Marchegiani: Yeah. And if we’re running— Let’s say, we’re running like our GI Map or our 401H and it’s looking relatively clean, then the next place we’re gonna go is the Breath Test. We’re gonna go Breath Test next ‘cause then, there may be some bacteria on there we not necessarily are picking up. And the Breath Test is kind of more of uh— a broad general spectrum because it’s looking more of the gases that bacteria is producing. So, not necessarily the bacteria, but it just tells us that there are bacteria there, producing gases if you will.

Evan Brand: How about the [crosstalk] organic acid?

Dr. Justin Marchegiani: The analogy is this, right? The analogy is this. You’re on top of the water. Is someone under the water swimming? Well, how do you know if you can’t see him? Well, you look for bubbles coming up, right? So, think of the gas that comes back on the Breath Test is like looking for bubbles on the surface trying to see if someone’s in the water.

Evan Brand: So, may I ask you this, too. What if someone’s like, “Aaaah! I don’t want to do SIBO Testing.” What about just coming in and giving some Broad Spectrum Antimicrobial Support— maybe we throw in some of the SIlver or some of the garlic?

Dr. Justin Marchegiani: Yeah. It depends. I mean, typically, when I’m recommending SIBO Testing, people are having more severe issues and the issues have been more chronic, and they’re just more motivated to get answers. So, it just depends, right? The more intense the symptoms are and the more chronic some thing’s been, people typically wanted to know what’s real. They want to be able to put their finger on it, so to speak. So I, typically, will recommend that. Uhm— if they said let’s just try it first, then I can get more to agree that, “Hey. if we didn’t get it to improve, then Round two.” “I don’t want to retest” I’ll try to get that negotiation moving.

Evan Brand: Yeah. So, long story short, you know— we try to base everything on labs cause if you don’t test, you’ve guessed. And we try to minimize guessing and checking ‘cause a lot of practitioners do that. We’re just not huge fans of guessing because you spend more money in the long run and the clinical outcome is not as good. Then that comes back on us. “Hey. Why didn’t it work?” “Well, ‘cause we’re shooting into the dark.”

Dr. Justin Marchegiani: . Well, also like. Let’s say, we come back. Let’s say, we did a Breath Test, right? And let’s say, hypothetically, the person was at a hundred for Hydrogen and 50 for Methane, okay? And then let’s say, we did a protocol. And let’s say those gases cut in half but they were still symptomatic. Well, does it kind of— Isn’t it nice to know that you had 50 percent improvement on some of those gases and that you’re moving in the right direction? Like, imagine you had a map, right? And— like Google map, right? And they only told you, you are on the right path once you got there.

Evan Brand: [laughs]

Dr. Justin Marchegiani: Well, don’t you have to want a confirmation that you’re moving in the right direction, right?

Evan Brand: Yep.

Dr. Justin Marchegiani: That’s kind of how I look at it. And the more complex and the more severe someone is, the more I like that because it gives me confidence as the doctor, that we’re doing the right stuff. But the patient is doing really well and some of the things and some of the things are really working well, then sometimes uh— I’ll let that one slide. But, I’ll let them know as a caveat that if— if we go in the wrong direction that’s gonna be our Plan B. And also I want to let people know what our Plan B is, just so they don’t think like, “Uh! Well, uhm— That’s all I got. I’m a one-trick pony,” Right? So, I want to let them know we got second options and third options, so to speak.

Evan Brand: Have you used a BioHealth? I know they’ve got a SIBO. I know they talked about a lot.

Dr. Justin Marchegiani: That’s the panel I use. I use the 900 SIBO Breath Test. .

Evan Brand: Oh, okay. That’s the best one.

Dr. Justin Marchegiani: I like it. It’s a three-hour.

Evan Brand: Okay.

Dr. Justin Marchegiani: It’s a three-hour test, and that’s nice to see the three-hour because you can get that whole window and you can see where it transitions at two hours to three, which is nice.

Evan Brand: Awesome. And then, what do you want to see on there? I mean, does that kind of like an adrenal profile where you’re gonna have a reference range?

Dr. Justin Marchegiani: Hmm— Yeah. We want to see Methane three or below, and we want to see Hydrogen 15 and below. Below 15, ideally.

Evan Brand: And— and— So, let me ask you this. If you have an overgrowth of good guys, you know, on the GI Map, sometimes, we’ll see the beneficial bacteria show up high. People always target these bad bacteria, but it— you can’t have too much of a good thing. If you have too many good guys, could that also show up and trigger those?

Dr. Justin Marchegiani: Well, if we’re running an Organic Acid Test, we would look at the lactate being elevated and if we saw that there, most people are gonna know because they’re gonna feel more bloated and gassy with probiotics. They’re gonna feel it. They’re gonna be more probiotic intolerant. So, we’re gonna know that, alright? There’s gonna be— you know, We’re gonna have specific symptoms that we’ll be able to see clinically. And then I would just be using more spore-based probiotics, instead.

Evan Brand: Okay.

Dr. Justin Marchegiani: That I’ll probably use Saccharomyces boulardii and spore-based probiotics. First is— you know, like in my line, we used like the Probioflor, which is like bifidobacteria lactobacillus. The unique thing about my Lyme is we have the Phagen. So, the phage does have some antibacterial effects and it comes from a non-dairy culture. So, a lot of people can tolerate mine. But if you’re just doing a run on the milk probiotics, and there’s no phage and— and there’s dairy in there, potentially, then there may be a problem.

Evan Brand: Yep. Yep. Well said. I think that’s it. I think we killed that one fast, but very effective. Were there any pieces to the whole protocol talk you wanted to mention?

Dr. Justin Marchegiani: I think we hit it pretty good, man. I think we’re really on the right track. Let me just see if we got any questions. I have kept my uh— question window down. I apologize for ignoring everyone.

Evan Brand: Let me see.

Dr. Justin Marchegiani: We got—  Oh, then we do now some questions. Let me see what’s going on here guys.

Evan Brand: Uh, Waled said that he hopes that we talk about Lyme disease treatment. Maybe we can do a whole podcast on that. I mean, Justin and I are continuing to learn more about the different protocols. There’s many protocols for Lyme.

Dr. Justin Marchegiani: I think a lot of people with Lyme are overtreated though. I think there’s a sequence that you have to go and work through. Like if you have a cute Lyme and you came back with uh— a bull’s eye rash, or you got any tick bite and then some symptoms follow right away, definitely go after that right away. But if it’s a chronic kind of thing, you need to get everything worked through. You need to get all your hormones work through, digestion worked through, diet and lifestyle worked through, worked through all the gut stuff, worked through the detox, and then get to the Lyme later. Uhm— so, a lot of people I find, I think, are misdiagnosed. Their immune system’s so screwed up ‘cause of other things, and then they’re seeing some Lyme come back, because, of course, everything’s gonna come back. Their immune system is down, right? It’s like, you open  your house up, and you got— you know, you come home one day, and there’s ten homeless people laying in the kitchen. Of course! Your house is wide open, right? [crosstalk] So, think of that as kind of like your gut when your immune system’s super low.

Evan Brand: Yep, well said. And, you know, the thing with the Lyme, antibiotics are very, very, very overused. And if you read some of the work that Steven Buhner’s put out. He’s got multiple books on this subject about antibiotics. Unfortunately, in many, many cases, for chronic Lyme, they just don’t work. And he’s seen a lot of people get sicker from the antibiotic. So, herbs, luckily Lyme and these other bacteria, they are still susceptible and allowed to be killed from herbs. Antibiotics— it’s not working.

Dr. Justin Marchegiani: And this is really important, too. This kind of dovetails with today’s podcast. If we do a whole bunch of killing, where does that all go? Well, it typically will and get dumped in via the hepatobiliary system and then obviously, some of the killing will happen in the gut. And then, what if our motility is not good? What if our digestion is not good? Well, it’s gonna back you up even more and you’re gonna reabsorb more of those toxins, right? So, that’s why we really want to make sure things are moving, digestion is doing good, our motility is doing good, our immune system is better. And then we have things that really help with uhm— coagulation, meaning, we’re keeping things moving. We’re not letting them— things get like static and coagulated and sticky and stuck. We want to keep it flowing.

Evan Brand: Yeah, well said. I mean, I think we may— maybe oversimplified the protocol talk, but part of that is just making sure that you’re not constipated. I mean, pretty simple, if you create all the garbage but you never take the trash out, that’s not good. You’re gonna have an overflow.

Dr. Justin Marchegiani: Totally. Totally. So, couple other questions here. Thanks Monmon for sharing the live show on your Twitter. I really appreciate it. Question for me. How old I am? I am almost 34.

Evan Brand: Nice.

Dr. Justin Marchegiani: Almost 34. Uh— Suggestions for root canals? I would uhm— do your best to try to read Ramiel Nagel’s book. I would do oil pulling and I would do your best to try to avoid it. See natural doctor. If you have to get it, get a full extraction. There is new research or new therapies coming [crosstalk] Stem cell therapy as well. I posted a video on my YouTube and my Facebook channel about it today. Take a look at that, justinhealth.com— I should say, facebook.com/justinhealthwellnessclinic, or click on the the facebook link. I don’t know what the topic is. I came in late. Okay— So, Pheochromocytoma. I think that’s a tumor on the kidney that produces excess aldosterone. I’m going back to like doctorate school physiology class. I think that’s the aldosterone-producing tumor. So, I mean, all the stuff we would do for cancer: Ketogenic diet, uhm— toxicity, coffee enemes, crucumin— all of that. I’ll let you hit the rest of them. Go ahead.

Evan Brand: Yeah. Let’s see what else we’ve got. Uh— Tessa. Wanting to know about starting Iodine, what to do to get started. Uh— Dr. Korosin talks about Iodine a lot in the aspect that many people are doing it, but if they have thyroid antibodies, it’s making the situation worse. So my advice would be get your thyroid panel run. Look for the antibodies first ‘cause you could if you have [incomprehensible], you could make yourself worse if you go start pumping a bunch of Iodine. And uh— Korosin’s got a bunch of literature he link’s, too about that conversation.

Dr. Justin Marchegiani: Keep the Selenium in there, two to four hundred micrograms. And once you’re stable, if you want to play around with some Iodine, hundred and fifty micrograms to start at one drop or one hun— 150 microgram dose, you know, per week, installing increase. They just make sure the B vitamins, the vitamin C, the Selenium, the Magnesium, and the Zinc are all in with it. And also, stay tuned for my Thyroid Reset Plan book that will be coming out in the next six months.

Evan Brand: Oooh!

Dr. Justin Marchegiani: It’s [inaudible] … draft for the first half of the book, just the other day, so I’m really excited about it.

Evan Brand: Congratulations.

Dr. Justin Marchegiani: Yeah. Thank you.

Evan Brand: Alright. Let’s keep going. Uh— Home remedies for flu and what to eat everyday to avoid s—

Dr. Justin Marchegiani: Uh— Remedy. Last week’s podcast. We did a whole podcast on it. Also I did a whole blog post: “What to do when you get sick” Part 1, Part 2. Part 1’s on the diet and lifestyle. Part 2 is in the supplements. So, that answers your questions right there.

Evan Brand: Man, Justin is killing it today. All great. Another question. Is it necessary to take HPA Access Support during a Kill Phase if you’re in Stage 1 or 2? I would say, it depends on your constitution. I think Justin would agree and…

Dr. Justin Marchegiani: Yup.

Evan Brand: … depends on your sleep, your stress level, how many hours are you working, how much rest are you getting. Are you working or are you off from working? What’s your circadian rhythm look like? Are you travelling? What’s going on? Like, what’s in that stress bucket?

Dr. Justin Marchegiani: I would say yes. It’s always gonna be good. And then depending on how much stress would be what we’d— what specific herbs we would recommend.

Evan Brand: Oh, we take adaptogens everyday, so we’re gonna say yes always.

Dr. Justin Marchegiani: Yes. I got some Ashwagandha here. So today, I’m crushing the Ashwagandha Supreme, right here. Absolutely. I’m gonna hit two right up now. I love it. It helps with my mood. It helps with sleep. It helps with energy. I find two. I can take it before bed if I— I get like disturbed or like stressed out, because— I don’t know. I watch the news or uhm— just something happens. Like, I just got some project. I got to do some deadline. Taking that really helps kind of curtail the Cortisol rush at night, along with uhm— some GABA and Magnesium, too.

Evan Brand: Yeah. I’ve been hitting Ashwagandha, the Reishi, the Motherwort, the Ziziphus, Albizia, the GABA, Chewable PharmaGABAs. I love them. Those were all good choices. “Hello, Dr. J and Evan. How much probiotics  are appropriate for a two-year old after antibiotic treatment for Bronchitis. If you’re looking into those infant strains that we’re using, some of the infant probiotics, typically— if we’re talking powders, it ends up being about…

Dr. Justin Marchegiani: Quarter teaspoon, right?

Evan Brand: … about quarter to a half teaspoon per day…

Dr. Justin Marchegiani: Yup.

Evan Brand: … for my daughter. We’re doing that currently. And she’s a little less than two years old but we just put it into her drink of water, and she just sips on it all day.

Dr. Justin Marchegiani: Yeah, and then for us, like my son Aden, I’m just like basically tipping my finger a little bit and some— Like I dump some probiotics on like the uhm— the container, and I’ll just kind of slip my finger and I’ll just touch it. And then I’ll apply it to his gums. Or like, we’ll put it on my wife’s breast, where like my child will feed from and just apply it there. And then, when he feeds, he gets the probiotics that way. So, you can do either way, if [crosstalk] they’re still not doing solids.

Evan Brand: That’s a good idea.

Dr. Justin Marchegiani: The infant’s strain’s great. That’s really what you want, I think, up to age four. [pauses] Yeah, up to age four, like that’s when you want to be just doing the infant’s strains.

Evan Brand: Uh— Tessa gave us some more follow-up about the Iodine question. She does not have a thyroid and has grave disease. Would that change your—

Dr. Justin Marchegiani: So, Dr. Wright has a protocol for graves where he does really a high amount of Iodine to basically overload the Iodine symport system, and then downregulate uhm- hormone Iodine or let’s just say thyroid hormone production. There’s that protocol. What’s out there? Dr. Wright’s— Jonathan Wright’s Protocol. I personally— and again, you need to be working with the clinician with this. Graves, it’s really serious. I mean, all of these conditions, I don’t recommend just doing Dr. Google. Like, we’re giving a lot of good information, which is great. But you really want to be working with someone in applying it. But for hypothyroid graves, we’re doing L-Carnitine, we’re doing Melissa and Lemon Balm, okay? Blue Flag— We’re also gonna be doing Lithium Orotate. Okay. And of course, an autoimmune Paleo type of template. I did multiple patients over two hands full that I had taken them out of grave-like states, so to speak.

Evan Brand: What’s the Lithium doing?

Dr. Justin Marchegiani: Well, Lithium has an effect on modulating the thyroid hormones.

Evan Brand: Oh, wow! That’s cool.

Dr. Justin Marchegiani:  Yeah. Lithium Orotate, we— I typically just uh— a formula used with the combination of Melissa or Lemon Balm and Blue Flag, and a couple of other herbs in there that are really helpful. The Carnitine, the Lithium; that’s gonna be great. And of course, you know, we added some Selenium, too, to help with the antibodies.

Evan Brand: Nice. Nice. Great. Great follow-up there. Very— Very good. Uh— does oil pulling really help? Yeah. It does. We’ve used uh— oil pulling ourselves. Both of us have, but there’s some— there’s some cool things you can do with it too. And there’s actually some testing you can do to look for all these different infections, like Hidden Cavitation infections. In the oil pulling, there’s some cool literature on like Silver and coconut, and all that, helping with like oral bad guys.

Dr. Justin Marchegiani: Absolutely. Vitamin K, too, is gonna be excellent for root canal stuff. Of course, collagen. Your teeth’s gonna be— have protein as well. So, good collagen peptides is gonna be excellent as well.

Evan Brand: Uh— last question here from Roslyn. “My SIBO test results are Methane 60+, Hydrogen 20; probiotics do not agree with me.

Dr. Justin Marchegiani: Yeah. Imagine, Roslyn. Are you also constipated, too? Can chime in there? Methane— typically, he put in a Methane diameter and a more constipated Hydrogen, dominate more diarrhea. You’re still positive on the Hydrogen, too. So you may have a— you may also alternate with the two. So, if you can Chime in there fast and let us know what your motility is like, I can answer you more specifically.

Evan Brand: Yeah. And we’ve used that ___[30:51] Formula. It’s got some of the Quebracho extract in there, which can help drop Methane.

Dr. Justin Marchegiani: Quebracho. [crosstalk] Love it.

Evan Brand: Quebracho. Sounds like a part here something. I don’t know.

Dr. Justin Marchegiani: I love it. It’s great.

Evan Brand: Like if— If Roslyn doesn’t get back to us, then we’ll just assume that if Probiotics are not agreeing and Methane’s that high.

Dr. Justin Marchegiani: So, of course, you know, if let’s say she is more constipated, then we would do things like ginger and natural prokinetics to keep things moving. We use ginger tea. Uh— maybe some of the Iberogast formula to keep things moving. Another support I used, called MotilPro, which is excellent. And then, we work on knocking down that bacteria. We probably hold off some of the probiotics if it makes it worse. But we’d make sure things are moving. Maybe even some uhm— Magnesium citrate to keep things moving too.

Evan Brand: Yep. Good advice. Vitamin C, too. You could pump by, what? Two to five grams or so. Vitamins C. That should be enough to move the bowels.

Dr. Justin Marchegiani: Probably a little higher than that, but yeah. I mean, I think, two maybe a little light, but definitely five to eight, five to nine will probably move it for sure.

Evan Brand: Okay, cool. Uhm— more more question here. Why can’t my eyes handle bright light? It could be due to the adrenals.

Dr. Justin Marchegiani: Adrenals, yup. Hundred percent.

Evan Brand: Typically, weak uh— weak adrenals, so definitely get your adrenals tested and looked at some of the adaptogens to help handle bright light. Like the people, you know, especially the women who come out of the grocery store. The first thing they do is pop down those sunglasses on and they just can’t live without them. That tells me adrenal problems.

Dr. Justin Marchegiani: Yeah. I agree. Hundred percent. Alright, cool. I think we answered almost everything. Would spore probiotics Just Thrive be enough to repopulate to the  gut after the Kill phase or should you rotate the— I would rotate other strains. I’m not familiar with Just Thrive. I’m a big fan of MegaSporeBiotic. We have it on our site, justinhealth.com/shop, under Gut Section. We’ll put the links in the Show Notes. I like that one. There are a couple of others that are out there that are really good. I know uhm— Primal Defense by Garden of Life is a decent one. I like the MegaSpore, though.

Evan Brand: Yep. Cool.

Dr. Justin Marchegiani: And then, Sue says, “My—” ‘Kay. So, I don’t know. Yeah, so that’s about the Pheocytochroma. Not sure if you have. That’s a tumor. So, you’d really want to get that uhm— resolved there with your doctor. But you’ve got to go on  like anti-cancer protocol for that. Uhm— hope that helped guys. Any other questions, comments, or concerns, Evan?

Evan Brand: I think that’s it for today. If people want to reach out. Schedule a consult with you. Check out Justin’s site, justinhealth.com. You can book a consult with him. If you like to book a consult with me, either of us, we’re happy to help you. You can just check us out; evanbrand.com is me. And make sure you subscribe to the YouTube channel here. We’re what? Thirty three plus thousand so— [crosstalk] Let’s get Justin up to fifty grand, you guys. and then a hundred, and then a million. So, subscribe, subscribe, subscribe, and share, because sharing is caring. And Education is the first step to greatness. How can you approach this stuff if you have no clue. You can’t. You got to learn, and then you can apply.

Dr. Justin Marchegiani: Absolutely. And just so everyone know, if you’re listening to us on YouTube. You know, we have the conversation and the video kind of going back and forth, so you can see our ugly mugs. But we also have the podcast link, and we are recording our podcast in super high audio quality. So, if you want to upgrade the audio, feel free and subscribe to our podcast channels. Again, we’ll have them in the show notes if you listen to Evan or I. We have the upgraded audio for you and that’s only been the last month or so. So, we’re really trying to up our game, guys. We want to make sure you get the best information at the highest quality on your fingertips.

Evan Brand: Yeah, so that’s on iTunes. So, look up Justin Marchegiani, or just type in Beyond Wellness on your iTunes or podcast app. And you can subscribe there. Cool thing I’ll tell about, Justin, iTunes just released a Podcast Analytic so now we can check and see our people actually paying full attention for the full episode or is everybody stopped listening after 20 minutes. Now we can see the drop-offs. That’s pretty neat. And then, for my show, it— just type in my name, Evan Brand, and you’ll find it.

Dr. Justin Marchegiani: Absolutely. I think if you go to evanbrand.com, there’ll be a link for your podcast. If you go to justinhealth.com or beyondwellnessradio.com, there’ll be a link there for the podcast. Click it. It will bring you to the button where you can subscribe. And then, we’ll make sure you get updates as soon as you can. And then also, if you’re listening on YouTube, smash the bell. YouTube’s doing some funny things you’re not gonna get the notifications if you are subscribed. So, hit subscribed and then smash the bell right next to it. That way, you’ll get all the notifications. And we’re gonna try to continue dropping lots of knowledge bombs. Let us know. Give us some comments below the channel if you’re listening on YouTube about this. We want to hear some of your concerns. We’re gonna work on responding on them a little more. And also, we want to get more feedback on what you guys want to talk about. So, let us know. We really want to engage you and bring more information. You know, our goal is to help, you know, ten million people. So, you know, we’re doing in the thousands range right now. We want to help more. So, allow us to help you by figuring out what your needs are and let us help you fulfill it, okay?

Evan Brand: Amen. We’ll see you guys after Christmas. So, I hope it’s good for everyone.

Dr. Justin Marchegiani: Yeah. Merry Christmas to everyone. Happy holidays, too. And hope you guys have a happy healthy New Year. And check out our hacking the holidays podcast. Lots of good solutions there so you guys can kick butt, stay healthy and not get sick throughout the holidays.

Evan Brand: Amen, brother.

Dr. Justin Marchegiani: Hey, Evan. great chat with you, man. You take care and Merry Christmas.

Evan Brand: Take care. Merry Christmas. See you.

Dr. Justin Marchegiani: Take care. Bye now.

Evan Brand: See yah.




Jonathan Wright’s Protocol by Dr. Jonathan Wright

Steven Harrod Buhner

Hacking the Holidays – Dr. J Live Podcast #160

Dr. Justin Marchegiani discusses different options, substitutions and modifications that can be made during the holiday season. Learn about what ingredients to use in some of the traditional Thanksgiving dishes including the turkey, stuffing and gravy that can help to still improve your health. 

Gain insight on the different modifications and options that you can use for some of your desserts so you can still indulge without having to feel guilty afterwards. Also, learn about some other cool options including meal timing, fasting, exercise and alcohol intake for a healthier you during this holiday season.Healthy Holiday Recipes

In this episode, we cover:

01:49   Grain-free holiday meal

03:01   Enzyme Support

05:55   Desserts Options

10:36   Timing Recommendations and Alcohol

15:00   Exercise



Dr. Justin Marchegiani:  Hey, everyone! It’s Dr. J here.  Evan, Happy Holidays, man! We got a short Thanksgiving Day week. I love turkey day, man. Some time with the family, really good eating. Are you excited too?

Evan Brand: I am and I’ve got blue skies here which is very unusual for this time of year. We’ve got sunny every single day this week. So I’m super grateful for that.

Dr. Justin Marchegiani: Love it. Yeah, it’s a great time of the year. It’s uh— important year, time of the year to be really grateful and to be extra uh— particular in all the things that we have to be thankful for. Coz there’s a lot of things but it’s easy to be so focused on everything it’s not there. So we got to really focus on all the things that are there. So couple that is just how about, just some really good Intel that we can use to hack our holidays. Meaning we can still indulge in feel good and connect with our family members but not go into a food coma and feel like absolute crap. What do you think about that?

Evan Brand: Agreed. Yeah. A lot of our clients recommend we do this subject because they feel deprived if they’re doing AIP or some type of dietary approach. They feel like that we’re the bad guys and we’re making their holidays not as fun. But that doesn’t have to be the case.

Dr. Justin Marchegiani: Absolutely. So, couple of things if you look at Thanksgiving, it can totally be Paleo, right? We have like basically the centerpiece in the Thanksgiving Day meal is the turkey, right? Awesome. Especially if we can go after the darker meat. That’s gonna be excellent. Good fats, right? Try to buy an organic or at least a Pasteur-fed turkey. It costs a little bit more but the nutrients are to be much higher, right? So you get good fats and proteins there. That’s the kind of a starting point. And then after that, you control your sides. So most people want mashed potatoes and maybe squash which you know, I’m okay doing a little bit more starch in the holidays. I’m okay with that.  It’s better than doing, let’s say a grain-based stuffing, that’s number one. Number two, we try to substitute for the things that we typically have grains. What’s gonna have grains? Well, typically, your gravy is gonna be thickened with flour so we do a gravy that’s gonna be a carrot and celery based and we thicken it with coconut flour if we do it. And we use the actual uhm— turkey stock from the actual turkeys. That’s a huge way to get to the stuffing, I mean the gravy going. And then the stuffing there’s typically some good stuffing recipes out there where we do a celery and carrot-based stuffing and it’s totally grain-free and it taste phenomenal. So, off the bat, you can have your starches. I’m okay with that. Number two, you have the gravy. Because the gravy kinda goes on everything. So if your gravy isn’t too good, you can really mess everything up coz you just basically coating everything with thickened uh—turkey giblets and flour. And then uhm—then after that, you have I mentioned your starches and then after that you can do cranberry sauce, really, you know, super Paleo. You can do like, I’ll do green beans and I’ll cut up some bacon, I’ll layer that on there, too. Uhm—those are kinda my big things off the bat and of course, a really good turkey. We’re gonna smoke our turkey this year. We typically use our smoker this time of the year. Any other thoughts, Evan, off the bat for your? Just with the Thanksgiving Day meal?

Evan Brand: Well, my thoughts are you got me hungry but besides that—<laughs>

Dr. Justin Marchegiani: <laughs>

Evan Brand: But besides that, the enzyme piece.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: You and want to talk about enzyme.

Dr. Justin Marchegiani: Yes.

Evan Brand: So let’s go into that. So one’s that you and I were talking about off-air was one from designs for health. It’s called allerGzyme. And this is more specific to people that if they’re just going to go off the rails, they are going to do or get it possibly get exposed maybe a cross-reactive issue with dairy or egg or soy or gluten or casein peanuts, things like that. You can take the specific enzymes. They’ve got like a patented version they call it what, Glutalytic in there.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: It is supposed to be pretty helpful. And they’ve got bromelain. Way but it’s a very, very super high dose bromelain which is a pineapple enzyme. It’s a really good enzyme. So there’s that. And then you and I both have our own custom digestive enzyme formulas that I say those are the best nutritional insurance policies that you can bring with you like a little glass jar or something.

Dr. Justin Marchegiani: Especially the fact that people forget that I uhm— having a meal like that is gonna be stressful not necessarily because it’s bad because obviously we’re gonna try to make the substitutes. We’re not gonna focus on eliminating. We’re gonna focus on substituting.  So we have the most healthiest options possible but because we’re probably gonna eat such a ton of food, it’s going to be a lot for our digestive system to handle. So we’re gonna really utilize more enzymes and more HCl and maybe even some bile salts to really optimize our ability to actually break it down.

Evan Brand: Yeah. I love it. I’ve got a small little old honey jar that my wife just keeps in her personnel and so if we go out to restaurant or if we got to family member, I’m just gonna pull out those enzymes and popp them down. So that’s can be my strategy and I think everybody who is dealing with bloating, gas, indigestion, a lot of these common symptoms heartburn, you’ve got that excessive heaviness feeling.

Dr. Justin Marchegiani: If you already got those symptoms and it’s not even Thanksgiving yet, then you’re a person who needs extra care when it comes to using enzymes.

Dr. Justin Marchegiani: Absolutely. So we talked about the meal. We talked about maybe the potatoes and/or the sweet potatoes or the squash. I’ll typically put some extra cinnamon on my squash, too, which is great for blood sugar. And the blood sugar and the insulin kina receptor sites that which is good. I talked about the green beans. I talked about how to maximize the gravy because the gravy is one of those things that’s gonna be layered on everything. So if you can fix the gravy component— and we’ll have in the show notes some Paleo uhm— gravy recipes so we’ll make sure we get some Paleo recipes in the notes.  Uh—we’ll make sure we get some stuffing recipes. Coz those are gonna be the the big— the big things—the gravy and the stuffing. Almost everything else, you can dial it in. The turkey’s pretty good. You can do really good cranberry sauce, you can do uhm— squash, you can do sweet potatoes, you can do regular potatoes or any other sides that we’re missing.

Evan Brand: Yeah. You hit the green beans.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Sometimes peas, sometimes carrots you.

Dr. Justin Marchegiani: Yup.

Evan Brand: I think honestly, if you’re eating real food and you just always think, “Am I eating real food?” you’re gonna be just fine.

Dr. Justin Marchegiani: Yeah. Then a couple of things—let’s go to desserts pretty fast. So we’re just kinda laying out the meal options or the meal substitutes, I should say, and then we’ll talk about little hacks that you can incorporate, too. So, off the, my Paleo Apple Crisp is something that I utilize a lot. I actually have it made once a week and it’s basically just a combination of the crust, which is gonna be coconut shreds, pecans and walnuts, kinda crushed up. And it’s gonna be kinda layered over some Granny Smith apples that are cut up. And the Granny Smith apples are basically mixed with butter. And they’re also gonna have a little bit of cinnamon on them and then we also have a little bit—

Evan Brand: I need this.

Dr. Justin Marchegiani: .. a little bit of organic palm cane sugar. And we like the organic palm cane coconut sugar because it’s got a glycemic index of 15. So it goes into your bloodstream a little bit slower and we try to use the least amount possible. So what I recommend is put the smallest amount whether it’s like uhm an eight of a cup or something in there. And just kinda glaze it and then mix it up. And then try a couple before you know, layer all the nuts and cook it. And then just see if it’s at the sweetness you want. So I don’t need a lot. I just put a very, very small amount. Once I have it, you know, typically, an eighth of the cup or sixteenth of a cup, a very—typically, I just glaze it. I don’t even h measure it. I just gently glaze it over so very small amount. And then once I have it to taste, then I pretty much put uhm—then it’s mixed with butter, of course, right? And then I put that topping right on top and there and then 350 for 30 to 45 minutes till the apples are nice and soft. And then you’re pretty much good to go.

Evan Brand: That sounds delicious. Did you invent that recipe or is that something you found?

Dr. Justin Marchegiani: No, I invented that one. That’s a good one. And then if you want mix it up, too, you want to make it more like a cake, you can do uhm—a tapioca and arrowroot flower and then typically you just add the arrowroot flour in with the apples, typically, half a cup to cup each. And then that kind of gives that more of a thickened flavor. And then you can just bake it not use the nuts. And then it comes more like a cake. And that’s a really good option. We have that Apple cake option on there, too. So, apple cake and/or uhm— the Paleo Apple Crisp. Apple crisp I think is a little bit more healthy coz you don’t’ have any flours in there. They’re all just a good healthy nuts and fats.

Evan Brand: Right. Yeah. I have a female client last week. She said she’s going to make a like a pumpkin pie but she’s going to do coconut flour and I think she said coconut flour and Coke and cashews maybe. So I know that there’s options out there. I just don’t eat too much dessert anyway, you know, besides a good piece of chocolate. But if you’re somebody who you’re going to go to one of these events and you think, “You know what I don’t want to miss out” Well then you just make it. You know, let  everybody else bring the meat and veggies. You just bring a healthy dessert. That way, you know that you’re gonna be safe and you’re not gonna cause yourself a flare-up or new problems.

Dr. Justin Marchegiani: Totally. For the most part, your turkey’s gonna be good, right? If you’re gonna do your mashed potatoes, fine. If you do cranberry sauce, if you’re gonna do squash, if you’re gonna do green beans or will do like uhm— Brussels sprouts with bacon, that’s typically gonna be good. You’re gonna mess it up with the excess uhm—gravy. So do the gravy right way and you do a healthy stuffing options. So I recommend is if you’re going somewhere, maybe you bring some gravy, or if you don’t bring the gravy, maybe you just uhm— bring the stuffing. And people won’t even know. We bring some of these healthy Paleo options we go places to get invited. People wouldn’t even know the difference a lot of times.

Evan Brand: Exactly.

Dr. Justin Marchegiani: The big thing is for me it’s about, it’s not about, “Oh, Dr. J, you’re being, you know, such uh—so tight about this. You know, why can’t you roll?” Well, the reason why  is I wanna feel freaking good afterwards.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Yeah. I wanna eat a lot and I want to feel good. And there are great options and I don’t notice a difference in flavor. I can make my option and it will taste just as good. So those are some good options. Anything else you want—Oh, also dessert. Just, you know, if you’re doing a pumpkin pie, you can just leave out the crust are there some really good gluten-free, crust options or you can do coconut uhm— crust option. That’s fine. And you can just do your pumpkin pie without you know, just the lower amount of sugar. That’s totally good right there. Uhm— is or anything else you want to mention for desserts outside of the Apple Crisp?

Evan Brand: I think you covered it. I mean you could bring along a piece of dark chocolate if you’re just super scared and you don’t want to go for any of the more processed things. Bring a cup— bring a bar of dark chocolate with there on the fridge when you get to your family’s house.

Dr. Justin Marchegiani: Yeah. And again, you could do Pecan Pie a little bit higher in sugar. You just have to make sure the crust is gluten-free. That’s totally fine, too. And obviously, just some really good maybe some coconut ice cream, coconut vanilla ice cream’s totally cool. And then what about supplement options? So we talked about, number one, the enzymes, HCL and digestive support. Number two, you could always add in some activated charcoal.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Activated charcoal. Number three, you could always throw in some probiotics later just to kinda help soothe and relax the tummy. Number four, well how about the approach like when do we eat the meals? So, number one, I recommend intermittent fasting and adding in some exercise in the morning. Even if it’s just a quick Tabata, or just a quick little weightlifting circuit where you kinda do upper-lower, upper-lower and just kind of a simple circuit for 15-20 minutes. Just something in the morning to really get the metabolism revved up. You may fast a little bit more. You may hold that fast a little bit longer than normal because you know that your gonna feast at the end of the day and all those calories will be coming in there to make up for that deficiency. Most aren’t gonna be working out on Thanksgiving. They’re gonna be relaxing and so it’s not as big of a deal.

Evan Brand: How about alcohol? You mentioned that off-air. You said we need to make sure we talk about that. So you’re recommending after meals instead of before meals saving?

Dr. Justin Marchegiani: Well, yeah, I recommend just have a little bit. Well, number one, there’s a couple of strategy. So I may do one glass just to kinda get that buzz in my system fast. It’s like, “Ooh, I could feel it.”  And then I’ll throw maybe a couple of things, a charcoal in, and then maybe there will be like a shrimp cocktail out and have a couple of little shrimps just to kinda get the protein, fat in there which kinda stabilizes my blood sugar level a little bit more so I’m not gonna go wonky. And then I typically just go with like a dry champagne or a dry Prosseco. So it’s very dry kind of a demi-sack, not a lot of sugar white and I like the sparkling. The sparkling has been shown to increase alcohol absorption. There was a—one study out of a bunch of college students. Can you imagine that? I would love to have been in the study in college where they gave them shots of vodka and then the other group got shots of vodka with carbonated water or like soda water. And they measured their blood-alcohol content and they found that the group that had the bubbles with their vodka had a much higher blood alcohol content for the same amount of alcohol. So, go figure. So what’s the moral of the story? You get— your alcohol goes for little bit longer of array when there’s little bit of carbonation or, bubbles in there. And James is saying, “What about Cheetos?” Yeah. So I would do Cheetos with my ginger Kombucha and a little bit of lime. The lime provides extra vitamin C, which is great for glutathione. The Kombucha has extra B vitamins and antioxidants and EGCG in there and uhm—probiotics. So it actually helps detoxify and help your gut microbes while you get a little tipsy.

Evan Brand: See that almost makes me wanna drink alcohol but every time I drink alcohol, I feel like I can’t comprehend simple things, like I like to I like to always have my brain going going going.

Dr. Justin Marchegiani: Totally.

Evan Brand:  And for me to shut off with the alcohol, it’s almost stressful. It’s almost like, “Nope, my brain is slowing down.” I don’t like this.

Dr. Justin Marchegiani: Well, we should make sure the demand on our brain is less.

Evan Brand: Right.

Dr. Justin Marchegiani: When the time—we’re not gonna be like opening up the champagne bottles when we’re seeing patients, right?

Evan Brand: Right.

Dr. Justin Marchegiani: We wanna make sure our patients get a 100% of our brain capacity. But when it’s the holidays and we’re just watching some football, and our brain is like 80% off, maybe it’s not that big of a deal.

Evan Brand: <laughs> For sure.

Dr. Justin Marchegiani: Yeah. But, yeah, we have the activated charcoal. We just have really good quality alcohol. Uhm— again, why does it matter? Coz I don’t want a headache. I don’t wanna feel crappy. I don’t want a ton of breakouts the next day. So we’ll choose uh—and typically, I’ll just get $15 bottle of really good dry Prosseco from Whole Foods. And I try to, you know, if I can go organic or you know, typically, the dryer ones are not gonna have as much sugar. It’s the sugar that’s gonna really throw you off. Uhm—you can also do the dry Creek wines. They have some decent stuff. Again, they don’t have a lot of bubbles like a lot of spike, Prosecco, I do that because number one, it helps with alcohol absorption. Number two, I just like the bubbles.  They don’t have a lot of options with that. So I will check out some of the whole foods or local stores, they have a very low sugar like as for a brewed or a Demi-Sec uhm—Prosecco option.

Evan Brand: The holidays are fun.

Dr. Justin Marchegiani: They are. Absolutely!

Evan Brand: I think our next month of episodes is probably be silly. It’s coz that’s the that the holiday vibe. It’s relaxing. It’s like, you know what, the summer time things have cooled off. It’s time to relax, time to rekindle, time to cuddle up, snuggle under your wool blanket next to a fireplace. This is a good time of the year.

Dr. Justin Marchegiani: I got a fireplace in my office so it’s actually nice coz I actually get to use it this time  of the year, so—

Evan Brand: That’s awesome.

Dr. Justin Marchegiani: So my dog just like—it’s basically a magnet for my dog. She just kinda—next to it all day. But, yeah, totally. And then uhm—you mentioned a couple things there. We talked about the alco—so yeah, really getting the exercise component going. Coz that really is gonna wring out a lot of the glycogen in your muscles. So think of glycogen as stored carbohydrate in your muscles and imagine you wringing that muscle out. You’re wringing that sponge out so all of that water in the sponge, all that glucose stored in the muscle now gets used up doing the exercise. Now what does that do? It’s like, well, it’s the equivalent of going and having a nice dry sponge to sop up a whole bunch of liquid drink that your kid knocked over, right? So you can just— that sponge is gonna work a lot better and be more absorbent. Think of your muscles as being more absorbent. So when you get extra carbohydrates into your uhm— body from your meal in your celebration that you’ll have a bigger sponge to soak it up.

Evan Brand: That’s a good idea. I don’t know if many people act on it but if they do, they’re gonna see a really good result. Here’s a question for Mike. He says, “It’s crazy. My Oura ring consistently shows my sleeping heart rate 5 to 15 bpm higher even after having just two drinks like red wine. I feel it the next morning. Any suggestions?” Justin, I know what you’re gonna say. Go ahead.

Dr. Justin Marchegiani: Well, alcohol can drop blood pressure. So it could be your blood pressure is lower than your heart has to be a little bit faster the compensate for that drop in blood pressure. That’s probably what it is.

Evan Brand: So you’re thinking maybe you don’t need suggestions. So I thought you might say, “Oh, just are you doing charcoal? Make sure you do charcoal.”

Dr. Justin Marchegiani: Of course, right? Like of course, extra charcoal. We can always throw some vitamin C in there, add in L cysteine. And we could even throw in, yeah like in our lines, we can throw in some detox aminos which is kind like your sulfur base, kinda NAC with a whole bunch of other sulfur amino acid in there. That— that’d be fine. I mean, I would do that. You can also throw a little bit of magnesium in there to uhm— to help with the with that component. But uhm—yeah, I would just look at potentially that just being the alcohol and just do all the things that help detoxify.

Evan Brand: Okay. Cool. Awesome. I think that’s everything we’ve hit. I don’t know if there’s any other piece to the holidays you wanted to go over.

Dr. Justin Marchegiani:  Yeah. I would try to time off like for me, I notice if I have felt any alcohol in my system when I go to sleep, I do not sleep nearly as good so I tried to give myself like a good three-hour washout period before bed. So I don’t have you know a lot of alcohol in my system. I just don’t sleep as good. I literally have more nightmares, I’m more active, I move around the bed a lot more. I had a glass of champagne before bed like a week or two ago and I like literally woke up at a right angle. So I was like laying across the whole head. I’m just way more active. Normally, I don’t move much at all. So again, if I I had that like at seven and I went to bed at like 10, it wouldn’t be a problem. But if I’m having it right up against bedtime, sometimes it could be the__ plus you know, I’m— I don’t know what the alcohol is when I go out if I order it. I try to order, you know, a nice low sugar kind but you have the bottle in front you look at it, so you just try to go off the waiter’s suggestions.

Evan Brand: Exactly. Yeah. I think it’s all good advice the liver-gallbladder support. I mean, that’s always helpful, too. So if it’s milk thistle or if it’s your Cordyceps mushroom. I mean there’s a lot of different products we use for for liver gallbladder support. One of the thing I was gonna mention, too, make sure that you check in with your practitioner if it’s Justin or myself. If you’re taking anti-parasitic herbs, some of these herbs can get intensified with alcohol. So one glass of wine may feel like four. You may not be able to make it home. See—take a  look and see what you’re actually using. I know some of these can create that sensitivity up.

Dr. Justin Marchegiani: Totally. Any other suggestions just like meal wise or anything that you guys are doing with your family for the holidays?

Evan Brand: I’m gonna bring some snacks just in case. I mean we don’t know the full spread coz we’re gonna go to like three or four different events.

Dr. Justin Marchegiani: That’s tough.

Evan Brand: ..this week and we don’t know exactly what people are cooking, what people are bringing. So just in case, I’m just gonna go ahead and bring uh—I’ve got a couple of some jerky like some jerky strips like some grass-fed steak strips that I’ve got and then I’ve also got a handful of macadamia’s of customer cons would also have coconut chips so I’m just gonna bring some snacks just have that in my wife’s purse just in case just in case we get somewhere and it’s just— I have been to a couple events where it was literally like a casserole, it was covered in cheese and that was the only—that was like the main entrée. There’s no way I could do this.

Dr. Justin Marchegiani: Totally.

Evan Brand:  Like you know, with enzymes, I’d be destroyed so uh—that’s— that’s about it. Just be prepared boy scout. Act like I was going to place that had no food.

Dr. Justin Marchegiani: Exactly. And again, there are some people out there where they may be really happy with her health right now. They’re just like, “Hey, this is a once a year thing and I’m just gonna cheat and really enjoy it. And that’s fine, too. But you know, still you can utilize some of the supplements and strategies we recommended so you at least doesn’t hit you as hard. And if you want to wreck if you want to apply some of the substitutes that Evan and I apply, and I’ve done it for years that in my opinion allow me to continue to feel good. I just— for me, it’s not just feeling good that day. I got four days off  work. I don’t take a lot of time off. I wanna feel good for those four days and I also don’t want to get sick either.

Evan Brand: Yup. Exactly.

Dr. Justin Marchegiani: Well, any other thoughts, Evan?

Evan Brand: I think that’s it.

Dr. Justin Marchegiani: So any other plans for you this week? Are you taking some time off from patients or—?

Evan Brand: Yeah. So Thursday, Thursday- Friday I’ll be taking some time off. My wife she’s can go out and participate in the consumer holiday on Friday. And I think that’s about it. I’m gonna try to spend some time out in the woods. I may— I may go out and and go for a deer hunt again. I want to get my own dear this year. 99% of it is just sitting out in nature listening to the birds but may be .01% of the time an animal walks by.

Dr. Justin Marchegiani: Totally.

Evan Brand: Really, it’s just my excuse to go do some forest bathing. I may try to do that.

Dr. Justin Marchegiani: What’s the Japanese term for that?

Evan Brand: Shinrin Yoku.

Dr. Justin Marchegiani: Shinrin Yoku. I love that, man. That is crazy. Cool. And we also add another herb to our parasite killing line, too. The mimosa Pudica. So I know will be adding that to our stores in the next week or two. It’s one of those things that we are kind of experimenting with. We’re helping to kill bugs and some of the wormies. So it’s something out there that if your patient and you want to inquire about that, we can chat about that very soon.

Evan Brand: Yeah. Stay tuned. I’ve gotten many, many pictures in my inbox of worms that people are pooping out from using this Mimosa Pudica. I was just a guest on the parasite summit, which is how I learned about this formula. And tons of people are taking it now and everybody’s saying, “Oh my God! My stool test showed up negative but I took this stuff anyway. And here’s what I pooped out. Surprise!” And it’s pretty nasty stuff. So Justin and I are talking off like, “Are you going to try some of the stuff?”  I’m guessing we’re gonna have to because we’ve been guinea pigs for everything else. So, who knows if we’ve got some hidden—

Dr. Justin Marchegiani: Absolutely. Well, what a great call today here, Evan. Happy holidays and Happy Thanksgiving for you and your family. And we’ll talk next week.

Evan Brand: Take care.

Dr. Justin Marchegiani: You, too.

Evan Brand: Likewise. Bye.



Justin Health Paleo Apple Crisp




Benefits of a Food Elimination Diet

What are the benefits of a food elimination diet

By Dr. Justin Marchegiani

What is an Elimination Diet?

What is an Elimination Diet?

An elimination diet is an eating plan whose goal is to determine food allergies and intolerances. It is a short-term plan, usually lasting between 3-6 weeks, that allows a person to learn which foods may be causing digestive distress, skin irritation, and brain fog. In an elimination diet, certain foods are cut out of the diet for a few weeks, before being slowly reintroduced, one-by-one, in order to pinpoint troublesome foods.

What to Eliminate

 Foods To Eliminate

The law requires foods to be labeled if they contain common allergens. The eight foods identified by the FDA are:

  • Milk
  • Eggs
  • Fish (e.g., bass, flounder, cod)
  • Crustacean shellfish (e.g., crab, lobster, shrimp)
  • Tree nuts (e.g., almonds, walnuts, pecans)
  • Peanuts
  • Wheat
  • Soybeans

These eight foods constitute over 90% of allergic reactions! However, allergy tests don’t pick up on food intolerances and sensitivities.

Foods to eliminate in a food elimination diet include some of the common allergens listed above: gluten, dairy, soy, and nuts, but also encompass the common culprits of inflammation, digestion issues, and brain fog. These include nightshades (eggplant, peppers, tomatoes, and potatoes), alcohol, and processed sugar!

Click here to consult with a functional medicine doctor to diagnose and treat any food sensitivities!

Benefits of a Food Elimination Plan

Food elimination plan benefits

Eliminating sources of inflammation will allow your body to heal and can enact a plethora of positive changes within your body.

Recovery from Leaky Gut Syndrome: Leaky gut occurs when the intestinal lining becomes inflamed, which can be caused by the consumption of gluten, sugar, or other foods you are sensitive to. The inflamed gut lining allows food particles and other toxins to slip through into the bloodstream, creating more inflammation. By eliminating the foods that cause the gut to become inflamed, it is possible to break the cycle and heal your gut!

Reduce skin irritations, such as eczema and acne: Dairy and grains are two food groups which studies have shown have a strong link to acne and other skin irritations. Try cutting them out of your diet and watch your skin clear up in just a few weeks.

Prevent/treat learning and attention disorders: Studies have shown that a strict elimination diet can treat symptoms of (and in some cases defeat!) ADHD. There is promising research showing that even just avoiding artificial colors and preservatives can also lessen symptoms.

Reduce migraines: You may have heard the gut referred to as the “second brain.” In addition to all the functions, the gut is in control of, the gut actually communicates with your brain as well! An inflamed gut (due to consuming “bad” foods), can send signals to your brain signaling migraines and headaches.

Reduce bloating, diarrhea, and constipation: We’ve all experienced the feeling in our stomach after eating something we know we shouldn’t have had. Eating problem foods causes a relatively immediate stomach ache and possibly diarrhea, but regularly eating foods you are sensitive to – even unknowingly – can actually cause long term gastrointestinal distress! People who have gone on food elimination diets often say they didn’t know there was something wrong until they cut out the foods that were causing them to suffer. It’s like a weight lifted from your shoulders!

Bonus: add in a quality probiotic supplement to help your good gut bacteria rebuild!

Help heal autoimmune conditions: Food sensitivities can create and worsen autoimmune disease. Not only is it possible to stop the severity of your autoimmune disease from worsening, but it is even possible to reverse your autoimmune disease by removing inflammatory problem foods!

Starting a Food Elimination Diet

How to start a food elimination diet

If you suffer from digestive distress, skin breakouts, rashes, or suspect you might have a food allergy or intolerance, an elimination diet is always a good idea. The antibodies your immune system makes when it reacts to a problematic food you’ve eaten take about 3 weeks to dissipate; imagine feeling like a whole new person in only 3 weeks!

A food elimination diet generally last between 3-6 weeks, and can focus on one or two specific foods, or it can target a wide range of foods. For a preview of what an elimination diet looks like, and when to add foods back in, check out our post outlining what you can eat and when you should reintroduce foods.

Consult with a healthcare professional to determine your best plan of action!







Foundational Nutrients for Optimal Health – Dr. Justin Live Podcast # 155

Dr. Justin Marchegiani and Evan Brand dive into the topic of nutrients and their importance to our bodies. Listen to this podcast and learn how B vitamins, Magnesium, Vitamin C & D, Selenium, Zinc and Omegas contribute to achieving a healthy body. Understand how these vitamins and minerals support different bodily functions and gain an understanding on how their deficiencies affect our health and cause unfavorable symptoms.

Explore other topics related to nutrients as they answer questions about leaky gut, H.pylori and some blood pressure medications which contribute to nutritional deficiency. Know some of the best sources of supplements and product recommendations which have been proven effective based on their practice and professional experience.

In this episode, we cover:

09:00   B vitamins

11:25   Minerals + Magnesium

28:15   Vitamin C, Selenium

31:18   Zinc

33:10   Omegas

36:26   Vitamin D

Just In Health iTunes

Just In Health Youtube Channel


Dr. Justin Marchegiani: And we’re back. It’s Dr. J here with Evan Brand, my man, how are we doing today?

Evan Brand: A happy Monday. If you’re watching in the future I guess the day doesn’t matter but for us it does.

Dr. Justin Marchegiani: I had a great weekend, man. I was doing a little waterskiing action today. It was phenomenal—actually yesterday, I’m sorry. Great, great day and back in the saddle for an awesome Monday. Got some patients coming up right after our live podcast. How about yourself man? Anything good happening for you?

Evan Brand: Uh—Actually, Yeah. I’m going to create a pretty cool piece of content as soon as you and I get off the call together, I’m gonna go eat some lunch and a I’m gonna drive about an hour away to a local hemp farm where there’s a guy who has a Kentucky hemp oil company that I’ve been seeing his products everywhere. His son was having a major seizure disorder. His son was having hundreds of seizures within a week. And he started to use cannabis extracts to help his son and now his son has not had seizures for years— several years. And so this guy he moved from Northern California where he was growing medical cannabis and now he’s just growing hemp in Kentucky and so I’m driving to the farm. I’ll probably end up doing a podcast with him coz I don’t think it’s gonna be easy to do it in the field, but I’m gonna  try to take my camera and puts— maybe a 45 minute little video together, try to interview him, get a little bit his story and share his products coz I’ve been using the CBD with my clients. And as you and I talk about with inflammation and the anti-anxiety benefits, you can pretty much use it with anyone. And it’s going to help regardless of the case whether it’s like Lyme or Hashimoto’s or H. pylori. Whatever we’re dealing with our clients, I mean we can pretty much use CBD across the board and we might notice some beneficial changes and it’s definitely not gonna hurt somebody. So looking forward to going to meet that guy. And stay tuned because I have a video probably the next week that’s gonna be published on it.

Dr. Justin Marchegiani: Love it. Yeah. I think CBD has some really good benefits. I use on handful of patients for pain issues, for sleep issues, uh—for anxiety, just from immune balance. And I do fine. It’s— it’s very good. CBD or Cannabis Diol is the non-psychoactive component of marijuana or hamper cannabis, if you will. THC Tetrahydro Cannabis that’s gonna be the part of the marijuana that gets you high and kinda gives you the munchies. So you get some of those benefits with the CBD without the, you know, the higher the munchies afterwards. And I’ve seen it work very well with seizures like you mentioned, very well with autoimmune and pain stuff. I mean it can be very therapeutic. I don’t think it fixes the root cause but I do think it’s very, very therapeutic. It can help.

Evan Brand: Right. Well said. Yeah. Definitely not gonna fix the root cause but I’ve had some people too that are in California, other states where they can even get recreational cannabis and I tell people go for it if they asked me because if they’re doing a tincture or they’re doing a spray or sublingual, they’re not having to smoke, they’re not having to use a vaporizer if they just don’t want to get the high, there’s— there’s tons of different options where you can do a high CBD. And a very tiny amount of THC where people can help fix their sleep. I had a __ in California she’s had chronic pain. She’s had Lyme forever. She said if she does CBD by itself, does pretty much nothing; but when she adds just like a milligram, so do say, 10 to 50 mg CBD, 1 mg THC, all the sudden the synergistic effect happens and the pain goes away.

Dr. Justin Marchegiani: Yeah. They can be very helpful. It’s a good tool in your functional medicine uh— pockets, so to speak.

Evan Brand: Yup. Hey, Robert, thanks for joining us. James, thanks for rejoining us. Our topic, well, we figure we’ll do a Q&A but our topic initially is about foundational nutrients kind of what the things that are actually worth your time and money because Justin and I were so many people come to us after they’ve been to other functional medicine practitioners. And we’ve got a kind of clean up the mess and there’s like 20 or 30 or 40 supplements that people are taking. And we like to try to whittle that down to just some of the foundations. And some things people are taking might help and can’t hurt, but if you’re spending a thousand bucks or something crazy amount on supplements, we really want to give you the stuff that just gonna move the needle coz why take something if it’s not gonna do stuff for you.

Dr. Justin Marchegiani: 100%. And again, kinda foundation before we go in is a Paleo template to start. And again, that’s macronutrient agnostic. It could be high-carb, low-carb, high-fat, moderate fat, high-protein, moderate protein, right? So we’re just focusing on the anti-inflammatory, nutrient dense, low toxin foods. That’s number one. And then from there, the next step above that is making sure we have the lifestyle stressors in order: sleep, hydration, uh—not eating when we’re really stressed, that’s number two. And number three is actually making sure we can digest the foods that we eat. We eat a really good diet but we can’t break it down. That’s the equivalent of going to the grocery store and leaving that food out on the counter, not putting it in the fridge for a week or two. It’s gonna rot. So the next step above that is HCL and enzymes and digestive nutrients so we can break those really good foods down. That’s our foundation. And once we have that, that’s where I think some of the nutrients come in. So with my patients, all of them, they’re on all either the Multi Nutrients Supreme or Multi support pack which has the extra, kinda stress handling nutrients that are gonna be in there which are gonna consist of high-quality B vitamins that are methylated or activated like P5P uhm—of course, like your B1, B2, right? Thiamine, riboflavin right? These are all—niacin—These are all important nutrients. Of course, activated LMTHF folate, of course, methylated B12 or some kind other adenosine hydroxy B12.

Evan Brand: Yup.

Dr. Justin Marchegiani: Uh—chelated minerals like calcium and magnesium and zinc and selenium, right? All chelated meaning they’re bound to specific amino acids, so that we can have better absorption. When we have an amino acid, kind of uhm—they’re next to it, it’s like an escort or a bodyguard for that nutrient to get where it needs to go in the body, if you will.

Evan Brand: Yup. Well said. A lot of these nutrients people are—I’m hearing feedback. What’s going on your end? Maybe your speakers are a bit loud.

Dr. Justin Marchegiani: I’m good on my end. I don’t hear anything here.

Evan Brand: You don’t? Okay. Leave us a comment in the YouTube if people hear the feedback at all, if you hear my voice echoing. A lot of people are so deficient in nutrients, even with an organic diet. And that is something that you and I see and measure on the stool test and then we see and measure that on the organic acids test, too. You know we’ve got a lot of people that come to us because they’ve heard us talking about like a ketogenic diet or some other high-fat diet. But then we can measure something called the steatocrit on the stool test. And so, if people wanna quantify, “Well how am I actually digesting”, “What can you guys teach me about my nutrients?” and “My diet’s perfect, I’m one of those guys, I want to try to fix everything with diet”, well, we can take a look and see if that’s actually working for you. So if we see steatocrit that’s high, that’s a fecal fat marker. You can look at your stool, of course, but it’s better to have a number. And if we see that your fecal fat marker’s high, well, we know we’ve got to give you some good fat digesting enzymes, help out the pancreas help out the gallbladder. And then also on the organic acids panel, we’re going to look at the amino acid markers, so we can see do you have the raw breakdown materials? Coz your proteins—like your animal proteins and pastured animal products—those are all made of amino acids. That’s like the breakdown products. Stuff like those and that’s what fuels your brain chemicals, your neurotransmitters and so, if we see you’re super low on amino acids, that’s a problem. So we have to fix it.

And like you mentioned, why is it happening? Well could be infections like Robert is  uh— he’s a left us a comment here. He is talking about that he’s had Blasto, he’s had Klebsiella, he’s had Citrobacter—

Dr. Justin Marchegiani: Yeah.

Evan Brand: He’s resolved a lot of his infections through Dr. J’s uh—antimicrobials,  which is awesome. I guarantee you are getting robbed for a long time of your—

Dr. Justin Marchegiani: 100%. 100% So the first thing is, right, we have that kind of diet. So think of like your health is like running a business. So every year that you’re unhealthy is like a business, right, having more expenses than its profit, right? Where then its revenue— gross revenue, right? So you’re going a little bit more into debt, a little bit more into debt. The difference is you don’t go into bankruptcy court, right, and go bankrupt. You have symptoms. And those symptoms eventually may lead into a cluster of diseases or pathology whether it’s diabetes or it’s just obesity or maybe it’s cancer or heart disease or you’re just in this in between where you kinda have chronic fatigue, you don’t feel good, you’re kind of depressed.  And then you’re in this in between where you go to the doctor and they’re just like, “Oh yeah, you’re just aging.” or “Here’s an antidepressant.” or “It’s all in your head.” And then you’re stuck with these kinda in between kind of diagnoses where you’re not— you don’t have a disease, but you sure don’t feel good and you’re not getting any answers, right?

Evan Brand: Yup.

Dr. Justin Marchegiani: So that’s kinda the big thing that we see. So we’re like, alright, so imagine that that’s the equivalent of business $1 million in debt. Well just because you start having good business practice and start pulling a profit, you gotta now make above and beyond that million before you start coming back in the black. So that’s where it’s really good for some of these supplements to come in because they kinda, you know, act like a mini bailout or a mini—a mini business loan to kind of bring you back in the balance. So things like B vitamins are great because you burn these up when you’re stressed. And if you have a lot of dysbiotic bacteria, these cre— the good bacteria produce healthy amounts of B vitamins. If you have a lot of bad bacteria, you’re not getting the B vitamins and you’re also getting a lot of toxins, too, which create leaky gut and create more stress and cause you to burn B vitamins and also creates a lot of lactic acid which eats a lot of your B vitamins. So B vitamins are really important first step. And we have B vitamins like B1, which is Thiamine or B2, which is Riboflavin or B3, which is Niacin and B6, which is Pyridoxine 5 Phosphate or Pyridoxine Hydrochloride, B9, which is Folate, uhm—B 12, which is amino, B12, right? Uhm—Methylcobalamin Hydroxyl  Adenosyl Cobalamin, right? These are important B vitamins especially if you’re a vegetarian. B12 is gonna be one of those that you’re missing. So any comments, Evan, on the B vitamins and how important they are.

Evan Brand:  Yes, sir. Absolutely. And I’m gonna address Robert’s question at the same time answering uh—or adding a comment. He said “Can these infections result in high homocysteine levels?” The answer is absolutely yes and there’s a journal that I’ll send over to Justin so we can put it in the show notes. It was American family physician was the literature but it was an article all about vitamin B12 deficiency and basically what happens is whether it’s H. pylori or like they even talk about in this article which is surprising coz most conventional medical people they kinda disregard parasites, but it’s talking about the link between parasites and B12 deficiency and then the link between B12 deficiency in elevated homocysteine levels. So, yes, we may give you some type of supplement, It’s gonna have the B12 like we always talked about. We’ve gotta get to the root cause, too. So we’ve got to fix those infections like I’ve had. We gotta fix those, too, at the same time while supplementing. So let me send it to you, Justin, so we can—we can share with the listeners.

Dr. Justin Marchegiani: That sounds great. I think B vitamins are really important just number one because of the stress component; number two because of the gut bacteria component; and then number three just to kind of—most people are still stressed so they need those B vitamins just to help kind of breakeven every day. So that’s the first component. Uh next let’s talk about minerals. So one of the first important minerals is gonna be magnesium because it’s a mineral that has over 100 or 1000 roles 1000 and enzymatic roles in the body, right? It has a major effect on dealing with enzymes. So with Krebs cycle, with energy, with blood pressure, with mood, with, sleep, with relaxation, with stress. Lots of different roles in the body and it’s one of those that are just incredibly deficient in our food supply. There’s lots of studies on magnesium deficiency and that’s it literally prevalent over 50% of the population. So this is important and if we’re not eating organic, then the magnesium in our food will be lower. So magnesium is one of these things that we wanna make sure is in a high quality supplement. I put it in my supplement via magnesium malate. So it’s bound to malic acid which is a Krebs cycle kinda intermediary nutrient. So it’s really important for the Krebs cycle and that way we can at least guarantee a couple hundred milligrams but because it’s chelated, we you know, it—more of it gets into where it needs to go which is really important. So magnesium is another one of those very important nutrients.

Evan Brand: Good. Well said. Yeah. And if you bought magnesium at Walgreens or CVS or Walmart or Target probably magnesium oxide, we talked about this before, but it’s about a 4% absorption rate. So if you’re taking 100 mg, you’re getting 4% of that; if you’re taking a 1000 mg, 4% of that. So take a look at your supplement bottle, flipped it around and look at the form of magnesium. If it’s oxide, you could use it for constipation that’s about the only benefit. But like Justin’s talking about the to help fuel the enzymatic processes and help Krebs cycle and promote energy and all that, it’s not going to do anything. You’ve got a look at the malate’s; you’ve got a look at the taurates; you’ve got the citrate’s; the—

Dr. Justin Marchegiani:  Glycinate.

Evan Brand: Glycinate, the threonate. So there’s many, many good ones out there. And Mercola, I don’t know if he’s just saying this like anecdotally or if he’s got some literature on it, but  Dr. Mercola’s recent talk about EMF and how he believes that the magnesium can help mitigate the EMF and he’s recommending like 2 g a day.

Dr. Justin Marchegiani: Uhm.

Evan Brand: — of different forms of magnesium. It makes sense, but I don’t know the mechanism of how that would help.

Dr. Justin Marchegiani: Interesting. Well if we look at the big magnesium foods, right? Magnesium is gonna be lower in foods, but it’s gonna be highest in our green vegetables— spinach, swiss chard, uh— pumpkin seeds uhm—you know, kefirs, things like that, almonds, some legumes, avocado, figs, dark chocolate—dark chocolate’s a really good one, uh— banana. Again, you just have to be careful because if you’re kind of having autoimmune issue, more on autoimmune template to start, well, seeds are out, any dairies out, legumes out, uhm— some of these—half your foods are gone.

Evan Brand: Yeah.

Dr. Justin Marchegiani:  So you have to be careful like the big things are gonna be high quality dark chocolate, uh—lots of good greens. And if you can do one of these nuts or seeds like the pumpkin seeds I mentioned, that’s a really good place. But if not, that’s were leaning on a good supplement is gonna be helpful, but the green veggie, I think will be the key uhm—to that. So we just gotta keep in in mind, you know, there may be some foods that are really good for us made nutrient profile but they may have an inflammatory profile that’s— let’s just say, kinda contradicts or kinda—the risk outweighs the benefit of getting that nutrient coz of the inflammation.

Evan Brand: Yeah. I agree. So if you’re autoimmune protocol, if your digestion’s compromised, which it probably is if you’re on an autoimmune protocol coz you probably had an autoimmune illness and that’s what we’re recommending an AIP diet. Sounds like a magnesium supplement will be much— much, much more necessary and helpful. Uh— we had a question from Linda. She said, should she be concerned if every time she goes to the stool, so every time she poops uhm— there’s an oil slick.

Dr. Justin Marchegiani: I don’t know if I would say– I don’t know if I would say scared but concerned, oh, right, yeah. I mean I would be scared if there was blood in the stool.

Evan Brand: Right.

Dr. Justin Marchegiani: Like you know decent bit of blood and it wasn’t just from a tiny bit of a hemorrhoid issue. But if I saw blood in the stool, I would be scared, for sure. I would definitely get that—some kind of a hem—some kind of an ulcer or cancer, make sure that’s ruled out. But with just the slick in the stool, I would be concerned because you’re not digesting your fat which means vitamin A, D, E, K your fat-soluble nutrients like your long chain fatty acids like EPA or DHEA or you know, coconut, good fats like that, you’re not absorbing those which means you’re gonna have blood sugar issues and you’re gonna have malabsorption, for sure.

Evan Brand: Yeah. Absolutely. So in that case, Linda, if you listen to us before, we’ll sound like a broken record, but if not, uh— you know, if you’re working with Justin or I, what we’re gonna end up doing with you would be looking at the stool test, we’ve gotta measure that fecal fat, the steatocrit marker, we’re gonna look for infections. So we’re gonna look for parasites; we’re gonna look for yeast; we’re gonna look for fungus; we’re gonna look for anything that’s gonna be stealing your nutrients or messing up that absorption. H. pylori if that’s suppressing the parietal cells that make hydrochloric acid in the gut. Now your whole digestive cascades is falling apart, we’re gonna look at medications. So if you’ve got a history or your currently taking some type of acid blocking drug we’ve got a factor that in coz that’s such a huge factor for fat digestion, too, if you’re just suppressing that. So we gotta look for those underlying causes but eventually, yes, we could fix the situation and probably add enzymes back in. Let’s address uh—Haley’s question, too, Justin, coz uh—it kinda ties into this. She said that she’s— her digestive enzymes can make your pancreas and gallbladder quote unquote lazy. What are your thoughts? We know that’s not true. With melatonin, yes, you can turn down the production of melatonin if you supplement. But with enzymes, my understanding is we’re only feeding the fire. Justin, can you comment.

Dr. Justin Marchegiani: Well even with melatonin I talked to Dr. Ron Rothenberg about that and he says long as the dose is relatively low that that won’t happen coz it’s a positive feedback loop with these things. But when it comes to hydrochloric acid and enzymes, one of the major feedback loops for HCl and enzymes is gastrin, right? And gastrin when you take supplemental HCl, enzyme levels are –or gastrin levels don’t drop. So it’s not like you get testosterone testicle shrink  in size.

Evan Brand: Yeah.

Dr. Justin Marchegiani: It’s not like that. So my bigger concern is that someone’s not making enough enzymes because they don’t have enough hydrochloric acid in the stomach and my concern is that’s— there’s not enough HCl on the stomach because of the sympathetic stress response, right? That fight or flight from food or from emotional stress or physical stress, so we, of course, we’re fixing that stuff upstream, right? Eating in a good, stress-free environment, not hydrating with food hydrating before, you know, we’re after biting after an hour or two but after, you know, 15 minutes before. And then we’re taking enough hydrochloric acid to lower the acidity so we can activate our own enzymes. But taking something is gonna be great coz I’m more concerned about that food sitting in your gut and not being digested and basically rotting and rancidifying and putrefying, creating stress by sitting in your gut.

Evan Brand: Yup.

Dr. Justin Marchegiani: That’s my bigger concern.

Evan Brand: I agree. So we hit the minerals. You talked about those you did great. We hit our magnesium which is gonna be probably number one. There’s a whole organization dedicated to magnesium deficiencies. If you type in gotmag, it think it’s gotmag.org. There’s like stage 2, 3 and 4 symptoms. You could even have insane symptoms, big issues, heart arrhythmias, atrial fibrillation, all sorts of other like heart-related issues due to magnesium, if you’re deficient. So if you’ve got some heart flutters or some weird symptoms, the cardiologist, they’re not gonna know you’ve got a magnesium deficiency, they’re just gonna end up putting you on like a beta blocker or some type of heart rhythm drug like they’ve done to my grandmother. And they’re not addressing magnesium and these drugs they’re using are likely gonna deplete magnesium even more. So we could get into some really, really big serious health implications if we don’t address something that simple as magnesium.

Dr. Justin Marchegiani: Oh, hundred percent. So again, big source of magnesium, in my line, I have one called Magnesium Supreme. That’s a magnesium malate. That malate’s are– the malic acid so that helps in the Krebs cycle, it helps with energy but also has a relaxation effect. So that’s one of the ones I formulated. I still even like a little bit of magnesium citrate at night. I think it’s great. It may not be the best absorbed, it’s cheaper but it’s still good. So I like my Magnesium Supreme and then we use the Malate— Magnesium Malate in all the multis. And the multi-nutrients Supreme, in the twice or in the Multisuper pack. So that’s kind of what we have. I like those. I use those daily. I think they’re great. And then for kids that may be uh—you know have serious gut issues, we may do like a magnesium threonate kinda gel to help or magnesium chloride kind of uhm—Epsom salt bath, too.

Evan Brand: Nice. And with the anxiety like PTSD, traumas, phobias, the supplement in my line is called Calm Clarity. And I’ve used that one with great success with people especially veterans who come back from war and they’ve just got a lot of emotional trauma or women who’ve been through some type of abuse threonate crosses the blood brain barrier. So that’s another form of magnesium and not any one form is perfect but you can use a combination of these. So like Justin mention, you wanna cycle. Maybe you’ve got some malate here, you’ve got some citrate here—

Dr. Justin Marchegiani: Yeah.

Evan Brand: You can add different forms.

Dr. Justin Marchegiani: Yeah. And then we’ll put show notes and links to some of these things. So if you guys want to support the show, we always appreciate that.  We’re just trying to get you the best information possible. Now, I talked about the magnesium foods. Some of the B vitamin foods, okay? Again, you’re gonna have like if you go online and look you’re gonna see the fortified ones which are gonna be cereals and orange juices which is basically crappy, crappy B vitamins.

Evan Brand: Garbage.

Dr. Justin Marchegiani: The worst quality. So do not count on any of the B vitamins from those foods. And number one, you shouldn’t be eating those foods, anyway coz they’re very high in sugar. With the orange juices and the grains are obviously gonna be the gluten thing which are gonna be inflammatory as well. So cut those out, nix those out. But you’re gonna do really with fish, with vegetables, with fruits, with meats, with leafy greens, egg yolks. So a lot of  the Paleo versions of those are gonna have super, super high amount of B vitamins which is great.

Evan Brand: Yeah. Like Pop Tarts, like fortified with 12 vitamins and minerals. It’s like, “Oh yeah,  let’s just eat pop tarts, high fructose corn syrup and genetically modified glyphosate sprayed wheat flour. We’re gonna be just fine.” Not true, not true, not true.

Dr. Justin Marchegiani: Remember, when you take in a lot of sugar and refined carbohydrate, all that refine carbohydrate converts to sugar and when you look at the Krebs cycle, how that Krebs cycle pumps around and it goes through all these kind of uhm—you know, reduction reactions where all these hydrogens kind of accumulate. It takes magnesium to run those cycles and if you’re basically—if it’s costing you more magnesium to run the cycle than you’re getting in, this is what we call nutrient debt, right? You’re not getting as much from it than you are— for the cost to run it, okay? So keep that in the back of your mind.

Evan Brand: Luckily the human body is resilient. I mean if that— if we we’re like a car, you and I use car analogies, if we we’re at such a nutrient debt like most people are, the car would be dead. But luckily our body will still survive. You just won’t thrive in these situations. You could have hair issues, skin issues, nail issues, like you said, autoimmune diseases, cancer, you’ve got bad skin, you’ve got acne, you’ve got poor sleep problems, you’ve got anxiety, depression, you’ve got chronic fatigue, you’ve got obesity. I mean, a lot of these diseases that have skyrocketed 10,000% over the last 20 years, there’s many, many factors that we can address in one podcast but like you mentioned, just a nutrient— the nutrient density of the soil has been reduced which is why—and I didn’t tell you this yet, but I uh—expanded my property. I bought the acre next door as well.

Dr. Justin Marchegiani: Oh, cool.

Evan Brand: I’m gonna have a 1 acre farm and I’m gonna have as much of my food come from that as possible. Not the meats coz there’s a couple restrictions on having animals but my goal is to provide 50% is my goal. Uh— 50% of my own food. I’ve already grown stuff this year. I’ve had watermelons. Last year, I had bunch of sweet potatoes, I had strawberries, I had broccoli, carrots, all organic homegrown. There’s no more local—

Dr. Justin Marchegiani: That’s great.

Evan Brand: ..that you can get than your backyard.

Dr. Justin Marchegiani: That’s great. And you can even team up with some farmers and make a deal and say, “Hey, you can use my land and I’ll give you half of what’s on there.”

Evan Brand: I know.

Dr. Justin Marchegiani: Coz then you don’t have to worry about it at all. And you kinda make this deal, they get free land but they get half the food. Hey, there’s enough food for you and your family. The rest may go bad anyway, so you may end up giving it away, anyway. So that could be a good deal for you.

Evan Brand: Yeah. I’m gonna try to do some pecan trees and I’ve got all sorts of ideas.

Dr. Justin Marchegiani: Cool. Yeah. Very cool, man. I think it’s important that uhm— people have to understand that your body is like a business. When a business starts having low profits and starts— the revenue starts dropping, the business has to either get incredibly efficient or typically, more than likely, lays people off, right? It fires people, right?

Evan Brand: Yup.

Dr. Justin Marchegiani: And it goes off, it fires people that are least essential to driving the profit. Well, the body does the same thing. It just starts allocating resources to other areas. Some dead skin, it’s okay, we’ll have some irritation, it will get wrinkly and creepy, it’s okay, no problem. Fingernails—weaker, more brittle; hormones will be a little bit lower that means you’ll have a lot of cycles, you know, symptoms with your cycle; you’ll have lower libido; you won’t be able to recover from strenuous work out; you won’t be able to put on muscle, that’s okay, no big deal. And uh—yeah, we won’t—we won’t put it– inflammation as much so you’ll be a little bit more achy, you know, you’ll be little bit more prone to osteopenia or osteoporosis. That’s how the body thinks. Uhm– that’s how it allocates. It’s all about survival. We are really about surviving. So those nutrients help run those systems. We really want to make sure that we have enough nutrients to run systems. There a lot of people they’re focused on calories and if you’re eating a real whole foods those calories will have nutrition, but today, it’s possible with the whole pop tart analogy or the junk food analogy, you can get a whole bunch of calories and not a lot of nutrition on the flipside. So you gotta keep that in mind.

Evan Brand: Agreed. You wanna hit a couple more questions or should we try to move the conversation into some more nutrients. I’ve had vitamin C just echoing in my brain that I have to just talk about vitamin C.

Dr. Justin Marchegiani: Let’s hit that. I wanna hit one last thing on magnesium and we can tie it to vitamin C. There’s a lot of the medications that are out there will actually create nutrient deficiencies. And one of the biggest ones are the blood pressure medications, the water pills, the Hydrochlorothi—Hydrochlorothiazide, the Lisinopril, the ACE inhibitors, right, the beta blockers. These will actually create magnesium deficiency which magnesium is really important for regulating blood pressure, so that actually create more blood pressure, which creates more dependency on these medications. So you can see that vicious cycle. So keep in mind the nutrient deficiency aspect with these drugs. Same thing with birth control pills and B vitamins as well and magnesium. So those are couple of common medications. And then the granddaddy of them all is gonna be the acid blockers that will affect nutrients in many directions, B vitamins, minerals etc.

Evan Brand: Yup. The Omni— is it Omni with an “n” or is it “m”? Omne—

Dr. Justin Marchegiani: Omneprozol. O-M-N-E and then prozol.

Evan Brand: Okay.

Dr. Justin Marchegiani: Yeah.

Evan Brand: That’s great.

Dr. Justin Marchegiani: Prilosec that’s the trade name of it. That’s the—Omneprozol is the generic. So yeah, these are the medications. These are the family of meds we got to be careful of. So, kinda tagging into your vitamin C. I’ll let you the ball with that Evan.

Evan Brand: Yeah. I just wanna—one more comment on the Prilosec.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And the thing that’s scary is these acid blockers used to be prescription and now they’re over-the-counter. So people just go to Target and they just go buy a 48 pack of these, six month supply and they throw that giant value pack 20% more pills into their shopping cart and they just go home, “Oh, yeah, Prilosec.” It’s like, “good God”

Dr. Justin Marchegiani: It’s really interesting because you know you get all the people that say, “Oh, you have to be such a super, super smart medical doctor to prescribe these drugs. They’re so dangerous. You need to have, you know, a medical Dr. kinda looking over you. And of course, that it—that is true with in a lot of cases, yeah, they contradict themselves coz then these drugs seven years later when the patent goes out, once they go generic and there’s no money behind them, they go over-the-counter.

Evan Brand: Oh my God.

Dr. Justin Marchegiani: Look at Ibuprofen, right? It kills 20,000 people a year and now it’s over-the-counter. It’s okay.

Evan Brand: Ugh. Insane isn’t it?

Dr. Justin Marchegiani:  Yeah. So I mean, you kinda talk on both sides of the mouth and you know, we pointed out. Uhm so, yeah, in general, the medications that you’re gonna see that are gonna be out there, primarily are gonna be the patented ones. Once that seven-year patents off or if they can create a mini-me version of it, then it’s over-the-counter and anyone can buy it. It’s up for grabs now.

Evan Brand: Fortunately, beta-blockers and antidepressants are still prescription only. So, that’s good. We’re saving a lot of issues with that. But yeah, let me get back on subject. Vitamin C is huge. It’s gonna be stored in the adrenal glands, typically.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So Justin and I are gonna  measure your nutritional markers when we run organic acids testing on you. We’re gonna look at a lot of nutrients. Nine times out of 10 vitamin C shows up low because people burn through it like jet fuel, just like B vitamins that Justin mention about stress, same thing with vitamin C. There is a reference range most people aren’t even on the map. I’m seeing people at like a point level, like a decimal point level when they should be hundreds of times higher. So I’m typically gonna be using about 2000 mg and I’ve had people say, “Oh Evan, I’ve taken vitamin C for years they still show up low because they were using some garbage they got at like a health food store. Even thought it’s a health food store could still have inferior quality or it’s a consumer break— consumer grade product they bought at Whole Foods or Amazon or somewhere else. And they’re not using professional grade or they’re just using ascorbic acid only, which is decent. But to really boost up the levels, you’ve got to have the antioxidants with it. The quercetin, the rutin, the bioflavonoids.

Dr. Justin Marchegiani: Mixed ascorbate.

Evan Brand: Yeah. You gotta have the mixed ascorbates, too. You’ve got the magnesium ascorbate, the calcium ascorbate, the sodium ascorbates. If you just do—like  what is it? emergency that garbage that they sell at the check out line at Walgreens or other places where it’s not only is it just rate ascorbic acid it’s got fructose in there, too, which is gonna destroy blood sugar. That’s not gonna do anything. You could buy a year supply of that and not move the needle. Dr. Justin Marchegiani: Hundred percent, man. So may—uh—Vitamin C is really important. I also say selenium is one of these things that are very important as well because it’s important for thyroid conversion. Uhm— it’s important for liver detoxification, it’s important precursor for glutathione, right? And we like to give that neither like a Selenium Glycinate or Selenium Methionine kinda bound to one of these sulfur amino acids.

Evan Brand: Let me ask you this.

Dr. Justin Marchegiani: Yeah.

Evan Brand: What do you say to all these people, “Oh, Justin, I don’t need Selenium. I eat three Brazil nuts per day.

Dr. Justin Marchegiani: Well I mean I think that’s a really good source of selenium; the problem is the amount of selenium in those brazil nuts can vary tenfold. So you could either be getting 50 µg or 500 µg. So the problem is you just don’t know how much you’re getting in each of them. So I think it’s good if you wanna do a Brazil nut or two a day.  Just make sure that the uhm—the multi you’re taking guarantees you at least 200 µg of selenium per day. And I think you’re in a really really, good place.

Evan Brand: Yeah. And we talked about the absorption issue. So if somebody has got some gut bugs, doesn’t matter if you eat the Brazil nuts. You could probably eat a whole bag and not boost up selenium, if you’re deficient and you’ve got things stealing your nutrients or compromising your digestive quality.

Dr. Justin Marchegiani: Exactly. And it’s just good to have that insurance policy with selenium. Uh—it’s gonna be hard to overdose with it if you’re in that 2 to 400 µg range and you’re using a good quality like Selenium Methionine. You’re gonna be in really good shape. And again, just kinda tag teaming, we got a lot of people talking about hormone stuff. Selenium is really important for hormones especially testosterone and then we even have Zinc, right? Whether it’s zinc aspartate or zinc methionine or uhm— zinc’s really important. The zinc fingers have a lot to do with the genetics like the DNA the epigenetics. So having enough zinc is really important to activating— having good affects our epigenome. Zinc is extremely important for making HCl. It’s a really good building block for our sex hormones as well. So gotta love zinc and when you’re stressed and you have low hydrochloric acid level, zinc can go low. And you can do is a tally test. We do some Zinc Chloride or—is it Chloride or Sulfate? I was getting confused.

Evan Brand: I think Sulfate for that.

Dr. Justin Marchegiani: Yes. So Zinc Sulfate. We could do a Zinc Sulfate test. The more metallic you’re tasting it is, the better— the better your Zinc is. The better or the more neutral taste, the lower your zinc is. That’s a good little kind of rule of thumb test.

Evan Brand: So people heard that, they’re like, “What the hell is he talking about?” So basically, uh—Justin and I can send a high-quality liquid Zinc Sulfate and based on the status of your zinc, that will change the flavor of the zinc. When I took this test a few years ago, I think they say, “hold it in your mouth for up to 30 seconds” So you put a little bit zinc in your mouth, you kinda gently swish it around. I swallowed it,. I tasted nothing. That was when I had all those infections. I literally tasted nothing. It tasted like water.  My zinc was trashed and then as you improve infections, you get your digestion better, your supplementing with the right type of zinc, all the sudden you could put the zinc in your mouth and then it almost tastes like your licking a piece of metal like right away. That’s the goal but would you say, Justin? 95% of people they’re not going to taste the metal right away which means they’re super deficient.

Dr. Justin Marchegiani: Yeah. I mean a lot of them are gonna be deficient if they have gut issues or stress issues or malabsorption those kind of thing for sure. So I think that’s a really important one look at. So we hit the Vitamin C, we hit Magnesium we hit Selenium and we hit Zinc.

Evan Brand: I’d say Omegas and vitamin D would be two others we have to mention.

Dr. Justin Marchegiani: Yeah. I think Omega-3 is really important which is—the typical Omega-3 fatty acids there is ALA Alpha Linolenic Acid. That’s the omega-3 in flaxseed oil. We have EPA which is 20-chain carbon which is Eicosapentaenoic Acid, that’s EPA. And then we have the_ DHEA. These are the 20 and 22. The EPA or the DHEA are the fats found in fish oil. These are the really important ones. These have all of the anti-inflammatory action. They help block this prostaglandin E2 pathway which gets inflammation jacked up. They also are really good building blocks for the brain and the neurological system. And the ALA are the Alpha Linolenic Acid from the flax seeds and the vegetables, that actually has to get converted via this enzyme, I think it’s Delta 5 Desaturase. And that enzyme converts the 18 carbon to the 20 carbon and things like insulin resistance and inflammation and stress can affect that conversion and knock it decreased function by 80 to 90%. So you’re not getting those really biologically active omega-3 fatty acids when you’re doing a lot of the plant-based Omega-3’s because of those mechanisms I mention. So getting the really good Omega-3’s from the fish is going to the best way. Plus the fish actually bio accumulate how the plants get it which will typically is the algae, right? A lot of the good vegetable, Omega-3 supplements vegetarian ones are gonna be algae based. Well the fish concentrate the algae. It’s kinda like the grass that cows concentrate the grass. So you’re kinda getting that bioaccumulation in a more concentrated form when you’re doing some of these really good fish oils.

Evan Brand: Well said. Yeah. Pastured meats, too, you will get some— you will get some fatty acid. So your bisons, your elk, which are my two favorites.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Your grass-fed beef, pastured pork. I would assume you’d get some from pork.

Dr. Justin Marchegiani: Yeah. More than likely you’re gonna get some from any of the animal products. The healthier they are, the more pastured they—the more pastured, the more biologically appropriate their diet is, uhm— the better chance that you’re gonna get more of these Omega-3 fatty acids than the more inflammatory Omega 6. But again, Arachidonic Acids are really important building block which is an Omega-6 fatty acid, but that’s gonna be a really good fat, too. So you don’t want to say, “Oh, all Omega-6 is bad. It’s just gonna really be a lot more  of the Omega-6 that are gonna be driven from vegetable oils like refined vegetable oils, right? The good vegetable oils are gonna be olive oil which is a—a Oleic Acid which is really an Omega-9, your—your uhm—short chain fatty acids are gonna come from your butters and ghee which that’s gonna be more animal-based. MCT oil or your Caproic, Caprylic uhm—Lauric acids. These C6, C8, C10, C12 fatty acids, these are gonna be in the coconut. That’s great. Uh—so those are gonna be some of the really good ones to start with. All avocado oils, another really good neutral one as well.

Evan Brand: Yeah. I just wanna point out the fact that we’re hitting a lot of really good foundational nutrients but we could do entire episodes just on magnesium, just on vitamin C.

Dr. Justin Marchegiani: Yeah. We have that on magnesium. I know that.

Evan Brand: I think we did. Yeah. So if—if we feel like we’re glossing over some deep aspects, then that’s okay. The vitamin D that’s huge. It’s really a hormone called vitamin but vitamin D is important we like to your levels at preferably 60 or above. I say nine out of every 10 people are gonna. be deficient in magnesium As you get older, you can’t convert sunlight into usable vitamin D as much. So even if you’re getting plenty of sun exposure which I’ve talked to people who garden for six hours a day, they are still deficient in vitamin D. And so in less— you’re like Dr. Mercola, where he said he hadn’t supplemented in seven years, something like that, 5-6-7 years, he lives at a very south latitude in Florida. He’s out on the beach hours— three hours a day with so much skin exposed and he keeps his levels at about 60. So I unless you got that amount of time and lifestyle to dedicate—

Dr. Justin Marchegiani: Totally.

Evan Brand: ..to sun, it’s gonna be really tough to keep it at adequate level.

Dr. Justin Marchegiani:  I hundred percent agree. So Vitamin D is really important. We try to do it with actual sun exposure, uhm— don’t burn, kinda get your Minimal Erythemal Dose, MED, if you will. And uhm— supplement the rest. If you can— if you just do a really good 25 hydroxy vitamin or a regular vitamin D3, mine’s uh—Emulsi D Supreme and it’s got the uh—MCT oil and the vitamin D3—D3 in there which is a really good form. Again, you can also add some K2 in it. My biggest issue is you don’t get enough vitamin D with the K2 ones but just make sure getting some really good K2 in your foods which fermented foods are  gonna have a lot of K2 uhm—a  healthy gut bacteria makes some K2 and then also a healthy grass-fed butter or ghee are gonna be other excellent sources of vitamin K2 as well.

Evan Brand: So Designs has one that’s got 5000 IU of D+ K warning K2. I can’t remember the name.  But it’s a pretty good one and I’ve used it before think. I think—I think it’s gonna be called the Su—I think it’s Supreme.

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: That’s what is it. D Supreme.

Dr. Justin Marchegiani: Yeah. The problem is the vitamin D levels in it are very, very low. That’s the only issue.

Evan Brand: I think it’s a 5000. What are you—what are you talking about using? You talking about using 8 or 10 thousand or is 5,000 good in your eyes?

Dr. Justin Marchegiani: It just depends. I like doing the liquid Vitamin D just because if I need to use it therapeutically like someone’s sick, right? I may do 100,000 IUs—

Evan Brand: Yeah.

Dr. Justin Marchegiani: And that ends up being like 20 or 30 pills. It becomes doing too hard, so it’s easier to take like 30 or 40 drops put in your smoothie and you don’t even know you had it.

Evan Brand: Well said.

Dr. Justin Marchegiani: I go more with the liquid, but again, your great vitamin K sources are gonna your green leafy’s, fermented foods like—like Natto, of course, Brussels sprouts, cabbage, broccoli, fermented dairy, prunes, uh—high quality uh— grass-fed butter or ghee. So you really, you know, you can get a lot of those uhm—make sure you’re getting a lot of good nutrients from those foods. Make sure their organic and that will help significantly. So if you’re doing a vitamin D, you really want to make sure that K2’s there and make sure those foods are really good in your diet and a lot of good multis and have a little bit of K2 in there, too.

Evan Brand: Good, good. Well said. Shall we look at a couple questions here?

Dr. Justin Marchegiani:  Yeah. Let’s hit them.

Evan Brand: Okay. So uh—we had a question about Mercola’s complete probiotic. It’s probably decent, Justin and I use professional grade. So if there’s a consumer grade product out there, we’re always gonna say ours is better because we’ve got healthcare manufacturers that make our products. There is very, very, very stringent restrictions in testing and manufacturing processes that we use and so were always going to push you towards our probiotics instead.

Dr. Justin Marchegiani: His is probably good, though.

Evan Brand: Yeah. I’m sure their good. I mean Mercola’s, you know, he’s very detail oriented. So I’m sure his are good but we’re biased. So we’re gonna want you to buy ours.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So you could check out uh—justinhealth.com Check out his line. He’s got several in the gut support section and I’ve got a few formulas, too, that I’ve got on my site evanbrand.com You can check out those.

Dr. Justin Marchegiani: Perfect.

Evan Brand: Alright. Let’s keep going. What else as we’ve got here? Uh— Robert he asked, “What foods and supplements can you take to speed up restoring low secretory IGA?” What do you think? I think a lot of the gut supports like the leaky gut formulas, your slippery elm, your marshmallow roots, chamomile flowers, anything that’s kinda fix a leaky gut situation maybe some mushrooms to support the IGA for the immune system.

Dr. Justin Marchegiani: Yeah. I think making sure the infections are gone, number one. Making sure the diet’s good. Making sure you’re breaking down the foods that you’re eating. Uhm— number three, once the infections gone, adding in a lot of the healing nutrients.  So in my line, we use one called, GI Restore, which is a lot of those same nutrients. Uhm—it’s got the glutamine, it’s got the slippery Elm, the aloe, the DGL, a lot of the healing, soothing nutrients. Getting the probiotics up is gonna be really helpful, you know, the Lactobacillus, the Bifidobacter strands, various strands there. Also very high amounts Saccharomyces Boulardiis is proven to help improve IgA levels. So those are really good things that you can add in there. And just making sure the adrenals are supported.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Because a healthy cortisol levels have a impact on your immune system which has an impact on your IgA. Coz your IgA is that mucosal that first-line defense for your immune system.

Evan Brand: Yes. So chronic stress, too, right?

Dr. Justin Marchegiani: Yeah.

Evan Brand: If you’re taking all the supplements in the world but you have a terrible boss and you hate your life, you’ve got to address that chronic stress component coz that’s gonna be the number one cause that’s going to drive down the secretory IgA.

Dr. Justin Marchegiani: Hundred percent.

Evan Brand: Uh—there’s another question here. There was a supplement a person had to had a tiny bit of soy lecithin in it should they be concerned? What’s your take?

Dr. Justin Marchegiani: I wouldn’t worry about soy lecithin. It’s tough. Uhm—soy lecithin is more of an emulsifier. It’s more to help with the digestion and the mixing of that product is typically not gonna be soy protein in that.

Evan Brand: Yeah.

Dr. Justin Marchegiani: The soy protein is really what causes the problems. Lecithin’s more of an emulsifier. So as long as it’s a good quality product uhm— I’m okay with there being a little bit of soy lecithin in there.

Evan Brand: Yeah. And I’ve got a couple formulas that have it in there. I’ve had people say, “Oh my God, I’m allergic to soy.” They’re fine. They have no issue. that’s not actually— it’s such a— it’s such an extracted form that it’s not like you’re eating soy. You’re not eating soybean.

Dr. Justin Marchegiani: Right. And then in my line, I think I may just have a few that have soy lecithin in there. But we were able to make sure that it’s guaranteed that it’s non-GMO soy. So you really want to make sure it’s at least non-GMO soy lecithin. And as long as that’s there, I’m okay with it.

Evan Brand: And it’s gonna be a tiny amount. When you look at the formula we’re talking and the other ingredients, it’s not an active ingredient. So could be 1% of the formula.

Dr. Justin Marchegiani: And less, you know, single digits fraction of percents for sure.

Evan Brand: Yup. Good. What else we’ve got here? If you feel like hitting this and we can, we can save it for another day—symptoms of chronic intestinal infections. I think we hit on that already with the hair, the skin, the nails, the acne, depression, anxiety, fatigue.

Dr. Justin Marchegiani: Yeah. All your— all your common symptoms, right? Your uhm— your intestinal symptoms: bloating, gas, diarrhea, constipation, bloating, acid reflux. And then your extra intestinal which are all the mood-based and energy-based: fatigue, mood, joint pain, depression, anxiety. Those kind of things, sleep,—

Evan Brand: Autoimmunity—

Dr. Justin Marchegiani: Hormone stuff, autoimmunity. And we got a whole podcast on that. So just google digestion or parasites or leaky gut and you’ll get a whole bunch of podcast and videos on that topic.

Evan Brand: Cool. Robert said he loved our podcast on histamine and it hit home prior to having infections no foods were problem, uh—post infection, fermented foods read havoc on him. So thanks for the podcast. Thanks for the feedback Robert. We love to hear that the histamine podcast was a killer one.

Dr. Justin Marchegiani: Yeah. I’m looking forward to chatting with you soon, Robert. I know uhm—you’ve been doing good work on your— on yourself there with uh— some of those good informational put in the podcast. But if you need more support, let us know. I’d get retested. Make sure we get to the root cause coz if those issues are still there with the post histamine stuff, there may be some additional critters hanging around.

Evan Brand: Yep. I agree. Another question about chronic dry eyes. “How often have you seen this with your patients? I’m working on healing the gut do you think there could be other root causes to dry eyes?” Justin, what’s your take?

Dr. Justin Marchegiani: Yeah. Chronically low cortisol. You’ll see load—you’ll see dry eyes. Typically, get your diet stable. Once your diet’s stable, you can add a lower carbohydrate kinda diet. If those dry eyes are still there, gently taper out that carbohydrate every couple of days. You know, 10- 15 g of carbs primarily at nights. Do the safe starchy versions: squash, sweet potatoes, plantains, those kind of things. And you may see those dry eyes start to go away. You can even try a tablespoon of coconut oil and a teaspoon of honey, right, before bed as well that may help.

Evan Brand: Cool. So what else we’ve got? “Can I re-infect myself with H. pylori with makeup like lipsticks that I’ve used when I had H. pylori? I’ve no idea what the lifespan of that is on the product.

Dr. Justin Marchegiani: It is possible. I mean I would just look at uhm—the lipstick stuff. Maybe just get a razor blade and cut that end off there. I think you’d probably be okay with that. Uhm— typically, you know, as you knock out the infection, you know, you’d still be using it. So eventually, you’d wear off that but I think if you wanna be on the safe side, I think that’s a good thing to keep in mind.  Even more important uhm—things that you can quite excise as easy like partners, right? Spouses. Ideally getting them at least treated semi- “semi” meaning maybe we only use one supplement just coz the compliance is so important. I would really be more—more imperative on the spouses and the partners.

Evan Brand: I agree. Partners are probably much bigger issue, much bigger carrier and reinfection source than your makeup and lipstick. I don’t know of any high-quality lipstick. Maybe they’re out there, but I would just throw that stuff away and maybe does discontinue using lipstick, too. I doubt you’re missing out on much in you know it’s— there’s parabens and all sorts of other stuff.

Dr. Justin Marchegiani: Yeah. And they have some really good things on the market now that do a lot like food-based ones where they are like extracting cherries and all these different food-based ones that kinda produces the fruit-based stain and kinda gives you a similar look but it’s using nutrition and foods versus, you know, some of the synthetic things.

Evan Brand: Uhh..okay, okay. So maybe you— maybe you stick with the lipstick then. Alright. James said he had a over sympathetic—let’s see having over sympathetic with sexual activity does blood pressure med Norvasc affect ED issues? That’s kinda like—I don’t even fully understand what you’re saying coz it’s kinda like a piece together thing. Are you understanding what he’s asking?

Dr. Justin Marchegiani: Yeah. I think what he’s saying is those medications have a potential side effect of erectile dysfunction? I would just go to RXlist.com and put that medication in there and look at that long list of side effects. I can—I can do it from right here while we continue with the conversation. What was the medication called again?

Evan Brand: It’s N-O-R-V-A-S-C. Norvasc.

Dr. Justin Marchegiani: Okay, cool. I’ll pull it up here in a second. N-O-R-V-A-S-C?

Evan Brand: N-O-R-V-A-S-C. as in Charlie.

Dr. Justin Marchegiani: Norvasc. Got it. Okay, cool.

Evan Brand: Then he’s saying, even with Viagra, it doesn’t correct lack of sensitivity.  So, yeah, I mean here’s my easy quick answer. If you didn’t have those symptoms before  and now you’re on this drug and those symptoms are happening, how could that not be a factor?

Dr. Justin Marchegiani: Yeah. This is a an—an—Am—Amlodipine, which is a basically a calcium channel blocker, okay? Which is a calcium channel blocker, which again, magnesium kind of does the same thing, FYI. And if we look at the side effects, uh—feelings like you may pass out, swelling in your hands feet and ankles, pounding heart beat or fluttering on your chest, chest pain, heavy pain spreading arms and shoulders, nausea, general ill and there’s more uhm— side effects as well. So—

Evan Brand: It’s like a commercial all of a sudden.

Dr. Justin Marchegiani: I know, right? Let me see here: dizziness, drowsiness, tired, stomach pain—

Evan Brand: What is this—what is that? That’s for blood pressure? Is that right?

Dr. Justin Marchegiani: Yeah. This is for blood pressure medication, but I think what you said is the best advice if that wasn’t there before and then you started taking the medication and it started happening, as long as your blood pressure is not too bad and you could taper down or you could come off with your doctor’s approval, uhm— I would have no problem doing that and seeing if those symptoms improve, then you know. Coz in the end, if it’s not a side effect on RX list.com but you take the meds out and it gets better, does it really matter that they say it is? We know clinically, right?

Evan Brand: Yep.

Dr. Justin Marchegiani: Absolutely.

Evan Brand: There’s so many ways. Didn’t we do a whole podcast—

Dr. Justin Marchegiani: Don’t—don’t come off. If your blood pressure is 160-170 and you’re on blood pressure medications, coz it will go that high afterwards, don’t come off it. You really want to make sure that if you’re on a medication and you wanted to try and see if there’s an issue, one, fix the root causes; but two, talk to the medical doctor that prescribed it and make sure they’re in concurrence—you know, in agreement with you on the taper that you’re going to do. Make sure they are on the same page.

Evan Brand: Yes. Some people they go to the other end of the spectrum where there are so anti-pharmaceutical that “I’m getting off of this.” That’s bad. You— that’s like stroke territory. So don’t do that.

Dr. Justin Marchegiani: You just gotta be careful. Some people if you’re like 130 or 140 over like 80 or 90, not too bad. You could probably come off as long as you’re fixing other root issues, but just have a blood pressure cuff by your bed, test it in the morning, see where you’re at. Just you— you want to do it responsibly. If you do it and you want to get to the prescribing doctor on the same page as you. You don’t want to go rogue.

Evan Brand: Yup. Well said.

Dr. Justin Marchegiani: Excellent. Any other questions you wanna hit up?

Evan Brand: Uh let’s see. What else we’ve got.

Dr. Justin Marchegiani: I have one here. We got one on Facebook here from Michelle or from

Mitchell. “Can L- tyrosine for dopamine support be too stimulating? How much should be taken to minimize side effects?” Yeah. It can be for some people. Uhm— tyrosine can kinda provide precursor supports to dopamine which then above that can go to adrenaline, so it can be. I think starting at 500 mg and working up to maybe, potentially 3 to even 6 g a day is okay. But start low and slow and if you know that it is stimulating, use it more in that first half of the day not the last half of the day.

Evan Brand: Yup. That’s a simple fix. Good answer. Uh—Nora had a follow-up here. “Thanks for answering the question. So can I successfully eradicate H. pylori and other pathogens as if I live with people who have it. Do they have to do treatment in parallel with me?” Well, if you’re sexually active with people, you’re kissing or simple enough, even just sharing straws, sharing cups, drinking after each other, that’s enough to infect them. So even if it’s not a partner, but it’s someone, “Oh, hey, let me have a drink  of that.” That’s enough to still pass H. pylori. Justin and I have seen it hundreds of times.

Dr. Justin Marchegiani: Yeah. The stronger your immune system is, it becomes less of an issue so like with Evan and myself, we have stronger immune systems coz we  work on that. We maybe less prone because our IgA levels are up high enough where the tiny bit of that in your system, our IgA would squash it. But if your IgA is lower and you got more the stress going on and you have poor hydrochloric acid levels, then for sure. That could happen.

Evan Brand: Yeah. And I had low IgA, too. So that’s something that you’d want it measured Nora and check with the stool testing and look for your IGA figure out which your first line of defense is looking like. If it’s low and weak, you’ve just got a lot of chronic stress, then, yeah, you’re gonna be more susceptible to—to pick it up. But to answer the question, “Could you eradicate it?” If you live with other people, yeah, you could but there’s gotta be a lot of things in your favor and you’re not sharing or sharing cups or drinking for most people or kissing them etc. Uhm— Anthony—well there’s one question about—from Anthony. He said, “It’s been over five years with gut issues, irregular stools, many doctor visits.” He found out that he had a whey and casein allergy. “Where should you start to get help?” Oh, wow! That’s a hard one to answer. Uh—right here. Justin and myself. justinhealth.com evanbrand.com I mean we’ve dealt with people who’ve already been to many doctors. I mean it’s such a common story. We always asked the question, “Hey, kinda give us your history. What—what’s been your experience with other practitioners? What have you tried to help? What have you tried that hasn’t helped?” I’d say 90% of people we talked with they’ve already been to a either a Gastro doctor or some other type of doc for their gut issues and they’ve had no success and only prescription drugs like I got recommended to myself anti-spasmodic, anti-acid drugs. If you’ve got a regular Bell’s, man, you’ve got infections. I can put money on it.

Dr. Justin Marchegiani: And I’m a huge believer— I want every patient to at least go in the conventional medical workup before they come see functional docs or functional practitioners like ourselves just to rule out big picture pathology stuff. You know, it just makes it so we at least know that the big glaring stuff is at least been looked at and addressed and assessed. And now we’re looking more functional imbalances which is really what functional medicine is treating. It’s not medicine from a conventional disease based medicine; it’s medicine from a uh— nutritional kind of support perspective working on supporting systems, not treating symptoms and disease.

Evan Brand: Yup. We’ll take one more question here.  Uh from Charlotte O: “How do you feel about NOW foods brand supplements my health coach is using them on me. I think NOW foods is okay it’s once again, a consumer grade product, so it is going to be likely less high-quality. I have seen some fillers and some of their products. I have seen them do some inferior forms of certain nutrients; however, they’ve also got a lot of really good products, too, where they’re stepping up their game in they’re using the methylated bees and the higher qualities with the Omega’s, so.

Dr. Justin Marchegiani: And plus, people doesn’t know. NOW has another line. It’s a higher up line. It’s called “Protocols For Life” That’s their higher-grade line. So if you like NOW, look at Protocols For Life.

Evan Brand: Is protocol uh—will that have to be through practitioner or is that?

Dr. Justin Marchegiani: Couldn’t say it’s a practitioner one but it’s a little bit higher grade but it’s—it’s made by the same company. It’s their one step up.

Evan Brand: But overall what’s your take on NOW?

Dr. Justin Marchegiani: I mean I think they’re okay for certain things. You know, uhm— so as a kind of initial kinda get in your foot in the door kinda thing, I think it’s okay. But of course, you know, we—we have are our bias because were trying to get the highest quality in everything. And part of that is because we actually work with patients face to face. It’s not like they go online and buy something, we never see them again. We’re working with them face-to-face so we have to know that what we’re recommending is the best because we need to seek clinical outcome. So we have to know that. So it’s a little bit different for us because we gotta go all out and make sure that nothing is held back.

Evan Brand: Right. So when you’ve got these other companies and people out there promoting stuff, they’re not working with people one-on-one. So it comes directly back on Justin or directly back on me if we give him our product and it doesn’t work. That’s not very sustainable for us. So that’s why it’s much, much better enough for us. That’s why we have access for people that don’t work with us. We allow other people outside to access our uh—products because they’ve been tried and true and tested. And if they didn’t work with people, we wouldn’t carry them.

Dr. Justin Marchegiani: Yeah. And if it doesn’t work, too, then it allows us to say, “Okay, there’s not some crappy filler or there’s some sub—sub nutrient in there. Let’s look a little bit deeper.” So it gives us the confidence that we just need to look deeper now.  So it’s gonna be on both sides.

Evan Brand: Yeah. And just a firsthand experience with NOW foods and the secondhand, I guess, through clients. I’ve had people taking like their super enzymes, for example, and I get their digestive health markers investigated on the urine and stool test, and it looks terrible. Their digestion is not working at all even with the high dose of their enzymes. So does that mean the quality is bad? Does that mean they’re not dosing it properly? Maybe they’re not consistent as much. I don’t know. Probably a combination of factors, but I always switch over people over to my professional enzymes and then I retest and then all of a sudden, it’s fixed. Is it compliance? Is it quality? Probably both.

Dr. Justin Marchegiani: Yeah. And you know everyone has got their bias and we kinda state our bias there. You know, we’re trying to be uhm— super transparent. Uhm—but yeah, I think there 95% of companies that are out there are bad. But I think that would be in that—I would say they’re in that 5% at least are better, for sure.

Evan Brand: Yeah. Yeah.  Well, that’s it for questions. Anything else you want to hit before we wrap it up. I think we did pretty good today.

Dr. Justin Marchegiani: Yeah. I think James uh—who is it—someone came out there—was it James—Yeah. James asked about Tom Brady. Again, love Tom Brady. Huge Patriots fan. Again Tom Brady does lots of things I would say go back and check out the podcast I did on him a year and a half ago for more specifics but he does use the green stuff. He does kinda promote like a Paleo-Alkaline diet. A lot of people have really uh—let’s just say Tom Brady like have a vegan cook. So because he had a vegan cook, Tom Brady was now on a vegan diet. No. He eats 20% meat. That’s far from vegan, okay? So just kinda keep that in the back of your mind. A lot of misnomers about Tom and he has a lot of a different training uh—modalities, too, that I’m hoping— I would love to get Tom Brady’s coach or strength coach on there.

Evan Brand: Or just get Tom Brady and the coach in a three-way podcast.

Dr. Justin Marchegiani: I would love that, man. I would love to hang out with Tom and get some secrets down. That’d be awesome. I think he may need to wait til he retires to truly unveil some of the stuff. But we’ll see.

Evan Brand: That’s true. That’s true. Well, reach out. I’m sure there’s a media/press person and tell him, “Look, we’ve got insanely popular health podcast. Uh— we’d like to interview Tom and his coach.” But yeah, they’d probably be like, “No way, dude. We’re not giving you the secret sauce, hold on.”

Dr. Justin Marchegiani: I know. I know. Exactly, so— I know Alex Guerrero is— is his—uh  coach that does a lot of the stuff. So I mean— really, really interested to get Alex on a uh— podcast. That’d be freaking awesome.

Evan Brand: Never hurts to ask.

Dr. Justin Marchegiani: No, absolutely, man.

Evan Brand: Well, let’s wrap this thing up.

Dr. Justin Marchegiani: Yeah. We had a great call today. I’m late for my next patient here, but uhm—keep dropping knowledge bombs all day, man. Really enjoyed this call with you. Anything else you want to add or say?

Evan Brand: Well I think we mentioned it all. If people wanna work with us, we work with people around the world. So Skype and phone consultations is what we do and all the lab testing except for blood you do at your house. So if you want to get help, get to the root cause, reach out justinhealth.com or Google  Dr. Justin Marchegiani or myself evanbrand.com or type in Evan Brand. Find us. Subscribe. And if you have more questions, concerns, get a hold of us. That’s what we’re here for. We love helping people. That’s what makes us thrive so we won’t help you thrive, too. So, have a great day.

Dr. Justin Marchegiani: And leave some comments below. If you like this podcast, tell us. Tell us what you like. If you don’t like stuff, tell us what you don’t like. And tell us what you want us to talk about next time and give us a thumbs up. Give us a share. We really appreciate it, guys. And you all have an awesome day, Take care you all.

Evan Brand: Take care.  












How To Do Intermittent Fasting Correctly

intermittent fasting

 By Dr. Justin Marchegiani

Today’s blog post will be about Intermittent Fasting and how to do it the right way.

We’re going to talk about what your goals are and how to achieve them, why you’re doing it in the first place and how to actually do it. Along the way, we will also be discussing the common pitfalls of intermittent fasting such as ‘how do you know if you’re someone that may have physiological or hormonal imbalances that may prevent you from getting the full benefit and maybe even getting worse?’

So let’s dig in off the bat!

What Exactly Is Intermittent Fasting?

what exactly is intermittent fasting

Intermittent Fasting is nothing more than timing up your food at certain times throughout the day and basically having a window in which you eat. That window can be anywhere between four to eight hours, and you close that window or widen it. You typically put that window in the last third of the day which is when you tend to be more insulin sensitive naturally.

Let’s talk about that window for example, instead of eating between 7AM and 8PM, that’s a thirteen hour window, we’re taking that and closing it down maybe to eight, or five, or four hours.

What Are The Goals of Intermittent Fasting?

goals of intermittent fasting

The first goal is we’re trying to increase lipolysis which will increase fat burning. The benefits that you get from intermittent fasting comes from that last meal — let’s say it’s at 8PM — all the way to the next day, now it’s twelve hours we’ve gotten so far. Then we’ll have, let’s say, until 2PM in the afternoon. We’ve added another four plus six, so we have eighteen hours of no food. So a lot of that benefit happens in that eighteen-hour time where we start increasing lipolysis.

The next goal is to increase cellular autophagy where our body starts recycling proteins. This also comes with the benefit of lengthening the telomeres.

And the third goal is to (HGH) and we’re making our body more sensitive to insulin.

Again, insulin and fat burning are inversely correlated. When our insulin is high, we can’t burn fat but when our insulin is low, we burn a whole bunch of fat. So the goal is to make ourselves more sensitive to insulin. So it’s like, the more sensitive your hearing is, people don’t have to yell or raise their voices for them to get your attention i.e. the pancreas doesn’t have to raise your insulin levels so the body can understand where to pull the sugar in and how to store the nutrients. When growth hormone goes up, that will help you put on muscle mass and we can combine this with good exercise allowing us to put on more muscle, which is great.

So the goals are all of these really good benefits above.

How To Do Intermittent Fasting

As mentioned in the example above, we get a 16-hour fast gig. So 8PM to 8AM — that’s twelve hours — and let’s say you fast until 12noon to 2PM, so you could have an easy 16 to 18-hour fast. With this you could have an 8-hour window for eating. If you want, you could extend the fasting from 16 to 19 or even up to hours. And depending on your choice, your window of eating could be anywhere between four to eight hours.

So in general, how we do it is take that window and we shorten it, so we’re trying to avoid breakfast. We could have a later lunch around 2 or 3PM. The key is we have to make sure that the window that we eat in is within the 8, 5, or 4 hour time frame. Personally, I like to eat later because I want to maximize the fasting time and if I eat a bit earlier that fasting time will be cut off so I would rather have that fast go really well.

The Common Mistakes In Intermittent Fasting

common mistakes

Mistake 1: Not eating enough fat

Fat helps sustain your blood sugar and it’s going to prevent the ups and downs of what’s called reactive hypoglycemia. It’s like your pancreas pulls one way while your cortisol pulls the other way which is not the best thing for your hormones. So again, blood sugar comes up, insulin comes up. Then blood sugar goes down, and adrenals come and pushes it back up. Definitely not the best combo. That’s why healthy fats are good. So one of the things that you get with the fast is you’re not eating. And when you’re not eating, you’re not pumping out insulin.

So insulin comes out most with carbohydrate, it comes out a little bit with protein, but very little with fats. So when you see people saying “fats are bad for diabetes,” they are typically talking about fettuccine alfredo — a whole bunch of fat with a whole bunch of carbs, right. But if we’re focusing on fat by itself, healthy good sources of fat like coconut oil or avocado, then you’re okay as long as you’re not  adding a whole bunch of sugar and carbs with it.

Mistake 2: Not eating enough calories

You actually don’t want to drop your calories so if you need 2,000 calories for the day, you got to make sure you get 2,000 calories in that eating window. So let’s say in an 8-hour eat window, you could have three meals in there. Maybe at 2 o’clock, a 5 o’clock, and an 8 o’clock meal. With the smaller windows, you could eat at one end and eat at the other end. Again, the benefit comes from the 16 to 18-hour fast.

Mistake 3: Having hormonal issues

If you have thyroid issues, blood sugar issues, adrenal issues, and female or male hormone issues then cutting out those meals may not be the best thing because you already have a stressed out physiology. So not having those nutrients come in at the morning time or the early afternoon may actually be a stressor on the body. Not getting enough calories is definitely a stressor, this is the biggest pitfall. People just don’t eat enough so if they’re having two meals, they have to realize, “well I’m only having two meals, I have to eat 50% more on each meal because if not, I won’t have enough calories.” So you got to remember that. So if you have hormonal issues like blood sugar, thyroid, Hashimoto’s, active gut, or any digestive issues, then it’s not a good idea to do fasting.

My advice is get healthy first, then this is a great modalities of trying on and fine-tuning things later. Also you could do a protein sparing fast in the morning where you eat a whole bunch of fat where you eat foods like butter coffee, MCT, and such as long as you just avoid protein. Then you kind of have this modified protein-sparing fast where you’re getting all the fat in so the insulin stimulation is very small. That’s a modified way you can tweak it so if you’re not ready to skip breakfast and lunch, you can do a protein-sparing fast in the first  half of the day and then bring in the other full meals later on at night.

So again, get your hormones dialled in. If you have an active gut issue, autoimmune issue, adrenal issue or male or female hormone issue, you want to get that fixed first. So if you need help with that, click here to schedule a consultation with myself.

So this is Dr. J signing off. I hope you enjoyed this post!

Magnesium Deficiency Causes and Solutions

Magnesium Deficiency Causes and Solutions

By: Dr. Justin Marchegiani

Magnesium is essential for proper function of over 300 enzymatic reactions and for the performance of many vital physiological functions: from heartbeat regulation to muscle contraction and relaxation. Magnesium is crucial to the body and plays a part in almost every facet of your well-being and that is why a magnesium deficiency can be responsible for almost every symptom dragging you down.



  • Boosts memory function
  • Muscle relaxation and sleep
  • Regulates mood and stress
  • Manages the excitability of the nervous system (calming)
  • Blood sugar control
  • Healthy bone density
  • Cardiovascular support
  • Detoxification pathways in the liver
  • Normal gut function
  • Inhibits calcium-induced cell death
  • Helps prevent osteoporosis, needed for bone formation
  • Vital for proper transcription of DNA and RNA

 A study on magnesium for insomnia in the elderly found that supplementation of magnesium improves insomnia through several measures, including sleep efficiency, sleep time, and concentration of melatonin.



Due to soil depletion and the omnipresence of processed foods, magnesium is becoming hard to find in the average American’s diet. Even within the health-conscious, high rates of prescription medications and antibiotic use lead to digestive disorders and impaired gut function, causing malabsorption of not only magnesium, but of minerals and nutrients in general, despite an otherwise clean diet.

Watching sugar and caffeine intake is important to ensure proper absorption of magnesium. Fluoride in our water supply can also negatively affect magnesium absorption.

A magnesium deficiency can cause:

  • Muscles aches and spasms
  • Poor digestion
  • Anxiety
  • Trouble sleeping and insomnia
  • Kidney and liver damage
  • Hypertension
  • Cardiovascular disease
  • Multiple Sclerosis
  • Alzheimer’s
  • Worsened PMS
  • Behavioral disorders
  • Mood swings
  • Osteoporosis
  • Depressed immune system
  • Cavities
  • Muscle weakness and cramps
  • Heart arrhythmias
  • Headaches
  • Nausea
  • Depression

…and pretty much everything else you don’t want. Neurosurgeon Dr. Norman Shealy says ,“Every known illness is associated with a magnesium deficiency […] A magnesium deficiency may be responsible for more diseases than any other nutrient.”

A study by the British Journal of Cancer in December 2015 looked at the incidents of pancreatic cancer by magnesium intake categories of 66,000 men and women, aged 50-76. It found that for every 100mg per day of magnesium less that was consumed, your risk for pancreatic cancer went up by 24%.

If you are concerned about a magnesium deficiency or have other health queries, book your intro consult today with Dr. Justin: https://justinhealth.com/free-consultation/



  • Leafy greens
  • Nuts and seeds
  • Fish, such as mackerel and salmon, especially eating some of the very small bones
  • Green beans
  • Avocado
  • Banana
  • High quality dark chocolate (It’s postulated that women crave dark chocolate around the start of their period because the magnesium helps with cramps and PMS symptoms)
  • Epsom salt baths are excellent as you have a large surface area (your skin) taking in the magnesium. Try 1-2 cups of Epsom salt (which is basically magnesium sulfate) in your bath for some incredibly relaxing effects.
  • An alternate mode of relaxation through magnesium would be to hop into a float tank. Taking in about a thousand pounds of Epsom salt in about 10 inches of water leaves you feeling incredible.
  • An alternate mode of relaxation through magnesium would be to hop into a float tank. Taking in about a thousand pounds of Epsom salt in about 10 inches of water leaves you feeling incredible.


  • Magnesium oxide only has about a 4% absorption rate and is comparable to table chalk. It’s cheap, easy to find, and works well as a laxative.
  • Magnesium citrate, as you find in such products as Natural Calm, is a step above magnesium oxide. It’s also rather inexpensive, works as a laxative, with a higher absorption rate.
  • Magnesium malate is very well-absorbed and acts as a calming agent rather than a laxative.
  • Magnesium glycinate is also calming without the laxative effect. It is well-absorbed as it binds to the amino acid glycine. The glycinate form tends to provide the highest levels of absorption and bioavailability, and therefore is ideal for those trying to correct a deficiency.
  • Magnesium threonate is a newer form which seems promising due to its ability to cross the blood-brain barrier and mitochondrial membrane.


If you are looking to get some extra magnesium into your diet, try Magnesium Supreme (https://justinhealth.com/products/magnesium-supreme/): a relaxing 50/50 blend of Magnesium malate and Magnesium glycinate.

To listen to Dr. Justin’s podcast with Evan Brand on magnesium, check out podcast #93: https://www.youtube.com/watch?v=9LWIGamxE2k










Immune System, Tapping Technique and GI infections – Podcast Live with Dr. J and Evan | Podcast #131

Dr. Justin Marchegiani and Evan Brand engage in a lively and informative discussion about their recent clinical successes with their patients using the functional medicine approach. Listen to them as they dig into the root cause of their patients’ issues and turn chronic and seemingly complicated problems into success stories.

Know about the tapping technique which involves turning something negative into a better, positive thought. Learn more about GI infections, the bacteria or parasite that may be involved, as well as the tests and treatment options that are proven successful in the functional medicine world. 

 In this episode, we cover:

 03:50   Immune System, bacteria, and infection relationship

 15:50   Tapping Technique

 19:17   Treating Hypochloridia

 24:10   GI infections

 28:34   Enzyme Tests






Dr. Justin Marchegiani: We are live on YouTube here. Podcast live on demand. Also, live here on Facebook. Evan, how are you doing, man?

And again, Facebook people you gotta click on the link here uhm—I’ll put in the comments to see Evan’s pretty face and go back and forth on this. How we doing, man?

Evan Brand: What’s going on? I’m feeling really good today. We’ve got a blue skies, the trees are blooming which they probably—

Dr. Justin Marchegiani: Awesome.

Evan Brand: a year ago in Austin. So I’m enjoying myself.

Dr. Justin Marchegiani: Very good. So we got podcast on demand. So anyone wants to write in some suggestions as we chit chat here, we’ll figure out what exactly we want to talk about moving forward.

Evan Brand: Yeah. And I might as well post a link over here to my Twitter page and see if uh—people are paying attention over there. That way, if they’ve got questions, they can get them answered here.

Dr. Justin Marchegiani: Love it. Totally makes sense. Same thing, anyone on Facebook, too, every  chimes in first we can get this thing moving. But let’s uh—just talk about some clinical successes in the last week with patients. Any updates from you, man?

Evan Brand: Yes. So interesting update is uh—there’s a female client that comes to mind and she had seven, I believe, I have to go back at here stool test and count. But I believe it was seven infections and this is a combination of two parasites which—let me just pull it up, that way, I’m not just shooting into the dark here, but—Uhm— with these infections, we started a gut protocol and symptom improvement was seen. She was having a lot of irritable bowel symptoms uhm— running to the bathroom. So she showed up with H. pylori, Blastocystis Hominis, Entamoeba and Fragilis and Proteas  and Citrobacter. Somehow, cal protectin level was still low  which is intestinal inflammation where—

Dr. Justin Marchegiani: Yeah.

Evan Brand: –I look at but I was surprised. And so anyhow, we put her on this protocol. And this is like 8 weeks.  And the H. pylori while it’s still positive, instead of two viral factors, now she’s got one viral factor. The level of H.Pylori has dropped. The Citrobacter is completely gone. The Proteus completely gone. The Blasto is completely gone. But we still got Entamoeba. So there’s still the parasite and there is still the H. pylori there. So we’ve got work to do but yet, we’ve seen 3 or 4 things disappearing. So I think what the takeaway message is from me is that the bodies gonna heal in an interesting way. It may not heal everything at the same time. Some things may be easier to kill. Some things may disappear first, but you gotta heal yourself especially your gut, your microbiome. You gotta heal these things in layers. And that’s what we’re seeing here.

Dr. Justin Marchegiani: Yeah. So typically with a lot of patients that have chronic issues is there are some underlying stress, right? Emotional, physical, chemical stress but even deeper above and beyond that, there is some level – there’s some level of  infection that’s deeper that creating inflammation even though it didn’t show via calprotectin or it’s just creating leaky gut. And the whole leaky gut mechanism is getting the immune system fired up. The more the immune system is fired up, it’s just an energy suck for  your body. It’s like uhm—let’s say guests in you guest bathroom that you never go into your house. And they just leave the water on. Just a little bit—little drip, drip, drip. And then you get your water bill at the end of the month, and you’re like, “Where the heck did that bill come from?” And you’re like, “Oh, yeah. The faucet’s on.” But it’s like that with your energy resources. When got these bugs, it really—when the immune system is overactive. And even just a leaky gut, right? The more your immune system is overactive, the more it’s gonna suck your energy dry. That’s why when you get sick, the first symptom you get when you get sick is what? You get a lot of fatigue and malaise coz the immune system is sucking resources. Go ahead—

Evan Brand: I wanna hear uh—a recent case from you, but first I wanna ask you the question that I get asked all the time. And the answer really doesn’t matter because we need to fix the root cause no matter what. But people often ask well– chicken or egg? Was it that ma—my immune system got taxed first? And then I picked up these bacterial pathogens or these parasites? Or did I pick up the parasite and the bacterial pathogens and then that that set my immune system? What’s your take? Can it go either way?

Dr. Justin Marchegiani: Yeah. So typically it’s one of two scenarios, right? Typically someone gets exposed to a very high amount of infectious debris, right? Parasitic—parasites. So you drink some really bad water, you to go Mexico, you have really bad meal or at a foreign country, you get the Bali belly, so to speak. And then you’re overwhelmed with all of that infectious debris and then there’s so much of it that it compromises your immune system, you get diarrhea, you have a lot of gut inflammation that creates malabsorption. That malabsorption puts stress on all of your glandular systems and then you spiral downhill. That’s scenario number one. So just the infectious—the infection was so overwhelming, it just threw everything else downhill. Scenario number two is there some type of immune compromisation  that’s happening. Meaning adrenal stress, poor diet, poor sleep, or poor diet and lifestyle habits, low nutrient density. The immune system’s kinda a little bit weaker underneath the surface then you get exposed to some of these infectious debris at smaller micro levels that are in the food. And eventually makes its way to the system and creates inflammation.

Evan Brand: So yeah—so let me—let me clarify there. If we’ve—If we’ve got diet, lifestyle mostly dialed in, but let’s say people are cheating with gluten, for example. They still got intestinal permeability going on. You can still have good class, good sleep, blah, blah, blah. But if you’ve got just a simple thing like leaky gut, for example, you could potentially be more susceptible to pick up these infections regardless of whatever else is dialed in.

Dr. Justin Marchegiani: Yeah. I mean—here’s the deal with leaky gut, too. If you’re creating leaky gut, and then there’s some research, you know, on the non-celiac, gluten sensitivity side of the fence, that looks at these foods. Even if you’re not like reacting to a it, like symptomatically, and even if you’re not like having like IBS -like symptoms,  bloating, you know, gas constipation, diarrhea, that gluten can still create leaky gut. Where the undigested food particles in the gut can make their way into the bloodstream and create stress. And then the LPS that comes in there along with that, that’s the— the bacterial debris can get into bloodstream and create a lot of mood issues as well. So you can still have leaky gut and not risk from gluten— and still not respond to gluten in general.

Evan Brand: Yup. Yup. I just posted a post on uh—Facebook which I think might be a slightly controversial which was I wrote this little bit of a letter and I put kind of like these five things that have happened over the last year or so where people have said, “Evan, I’ve ditched psychiatrist or I’ve ditched my psychologist or my marriage counselor, or my conventional doctor because of functional medicine.” I kinda wrote the reasons why of how if you lower inflammation, you may need less adjustments at the chiropractor, for example. If you heal the gut, you start producing your neurotransmitters optimally, you might not you’re your antidepressants anymore, so you might not need your psychiatrist. Or if you heal your adrenals, you’re not gonna snap at your children anymore, so therefore you’re not gonna need the marriage counselor that is telling you need to stop yelling at your kids. And how basically how functional medicine can literally, not intentionally, but it’s just a side effect is that we can replace these other industries. I’m not saying these other industries are bad for mental health care or anything like that. But a lot of times, this is not root cause medicine. And my wife and I went out you with a friend of ours yesterday and she said she had a lot of stress, she had to put her dog down and she called up her psychiatrist and said, “Hey I need help, I’m freaking out.” What does he do? He prescribed her 60 Xanax and says, “Here’s your Xanax bars and take these.” And I told her, I said, “Listen, your anxiety and your stress from this issue is not a Xanax deficiency.

Dr. Justin Marchegiani: Totally.

Evan Brand: How about we do some emotional freedom technique. We start tapping. How about we cleanup the diet? And then before we left, out the parking lot, I had her do the quick coherence technique, the Heartmath, like the heart focus breathing.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And focusing on someone that she loved and we got done with it, and she said, “That was weird.”  I said, “What happened?” And she said, “I got tingly and warm.” I said, “Oh, it worked.” And she said, “What happened?” I said, “Well, you just took yourself out of fight or flight that you’re probably stocked in which is causing you to be dependent on Xanax and now we’ve pushed you into that parasympathetic rest and digest mode.” And she feels better. And this is what this is all about. Uh—a little bit of uh—off-subject uh—, but I just wanted to mention to people, check on my Facebook post and you’ll read about what I’m saying. I’m not saying these other uh— practitioners out there are garbage. What I am saying is that if you’re not getting a practitioner to focus on root cause, even if they are psychiatrist, if they’re not a root cause psychiatrist, then what the hell are they doing?

Dr. Justin Marchegiani: It’s all about resources, right? And in functional medicine world, we’re trying to help enhance your resources. So just like someone with more money in their bank account can buy more things, well if we enhance our mental, emotional bank account via healthy and diet and lifestyle functional medicine principles, we have more resources to deal with stress in our life. Whether it’s family, friends, being a parent, being present for our partner, just being able to do the hobbies of a hobbit—hobbits—uh—

Evan Brand: Haha

Dr. Justin Marchegiani: The hobbies and the habits that we have going on in our life.  I got uh—I guess I’m missing my uh – Lord of the Rings movies there. Yeah. So—It ‘s all about resources, right? So we have to make sure that we have enough resources in our system so we can allocate them toward these stressors. And I always tell my patients, “Have you ever tried dealing with stress on 0 night sleep? or “Try doing your taxes the next day when you’re getting like three hours of sleep?”  You’re just  not gonna be able to handle it. You don’t have the resources. So everything we’re trying to do is let’s test the resources of our body systems, let’s look where the hormone’s at, let’s look at where the gut resources are at, let’s look at detox and nutrient resources are at, let’s support them and let’s work on fixing them.

Evan Brand: Well, the analogy I like to use is we’re just using a big spotlight. Because a lot of different industries and health care, what they do is they use like a little laser pointer or like one of those tiny little keychain flashlight. And they shine something real dimly into one corner. And you’re like, “Oh, Justin looks like we found something. We found some anxiety issues, here’s the Xanax.” But instead, we come in with a giant spotlight and we’re like, “Whoa, look at the left corner of this microbiome. We got parasitic and bacterial infections, which can steal your nutrients, can mess up your blood sugar and cause anxiety. Look over here,  we’ve got some adrenal issues. You got spiking of cortisol that’s gonna need to be addressed.” And then we shine the spotlight over here, “Oh, take a look at our detox pathways on the organic acids, you’ve got trouble over here.” And “Oopp, we shine the spotlight behind us, here’s mitochondrial issues. This is why you’re so fatigued.” And that’s the—I think that’s the greatest analogy. It’s a little laser pointer or a little small keychain flashlight, which is just pinpointing one industry of psychiatry or psychology or whatever versus exploring everything. Which is why for you and I, it’s tough for us to become the blank guy. You know people out there, “the thyroid guy” “ the detox chick” “ the bone broth chick” You know what I mean? It’s really gonna be tough for you and I to just say we’re the blank person because I don’t want to limit myself. I wanna let everyone know it is all encompassing.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And if rest and niche yourself down, I think it’s a bad thing.

Dr. Justin Marchegiani: Yeah. Like from a marketing standpoint, right? Marketing is just telling the truth attractively. You know it’s good to have the niche because you wanna reach the people that have special conditions. Because if like, my specialty is thyroid. Number one, I have—I have or had a thyroid issue. It’s under control. Autoimmune thyroid issue. So I’m more passionate about that issue. But again, to treat  a thyroid issue, you have to be able to treat all of the systems. So it’s kind of a mythology, like you don’t just ever treat thyroid, you treat the whole thing. But you may mark and put information out there that’s gonna resonate and speak to someone with a thyroid issue more. But again, the underlying issue is from education and clinical standpoint. We’re addressing the key underlying surface issues and the deep root issues as well. So we’re never ignoring it. We may speak to someone uhm—more specifically and get into the more nuances of that condition, but it all comes back down to the foundational stuff that we always talk about.

Evan Brand: Right. I would say my specialties would be— it’s become parasites really. I mean, I’m seeing so many each week and it’s just so fun. I guess because I had parasites.

Dr. Justin Marchegiani: You had a parasite, you.

Evan Brand: Uh—Yeah. And also depression, I mean because depression is what got me into this whole thing. IBS and depression in college, I mean, like I told you before, I had to figure out when I went  into a college class, where’s the bathroom. Coz I have to get out in the middle of the class to run to the bathroom.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And so for me, depression, IBS, parasites, you know, those are all linked together—the whole gut-brain connection. And I really am empathetic for people that have struggled with that because it’s so common and if you diagnosed with IBS, that’s a pretty generic diagnosis. And unless you’re with functional medicine practitioners, you’re gonna get an acid blocker, an antispasmodic—

 Dr. Justin Marchegiani: Yeah. Absolutely.  

Evan Brand: — or some other drug and—

Dr. Justin Marchegiani: Well actually, you were diagnosed with IBS, right?

Evan Brand: I was.

Dr. Justin Marchegiani: And you use the antispasmodic, you used the medications that helps with the gastroparesis. You know—

Evan Brand: Well, they never –

Dr. Justin Marchegiani: They even do that—

Evan Brand: Well they never got to use it. They try. They wrote me the prescription pad but I denied all three of the drugs.

Dr. Justin Marchegiani: And the thing is, too, we can also use natural medicines for a lot of those things. That may not fix the root cause, right? There’s root cause medicine and there is using natural medicine in a way that’s gonna help alleviate the symptoms that’s gonna up regulate physiology so things work better. But we have to still be investigating and digging to the root cause, right? So we’re dealing with someone with gastroparesis or low motility, we may add in things like ginger. We may add in things like carnitine. We may add, you know, higher amounts of mag citrate to keep that uhm—migrating motor complex moving. But we are still digging in deep. We’re still making the diet, the lifestyle. We’re still enhancing digestive nutrients, uh—hydrochloric acid enzymes. And then we’re digging deep for the infections. And we’re trying to lock in those diet and lifestyle habits, right? The supplements are great because they can give us that symptomatic relief while we continue to dig over here to the root cause. So as long as you have, you know, that  four pace envision that addresses some of the symptoms without the side effects, you know of some of the drugs, which may have more side effects than what you’re treating, and then working on the functional medicine plan, I think we’re in a really good place. 

Evan Brand: I agree. Yeah. I actually got a good—good success with that IB Synergy product from designs which get Bonigut in there. It’s got the 5-HTP. I had a guy with just super bad IBS and I said, “Man” I mean he was critically, critically stricken with both diarrhea and constipation just alternating every other day.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So I have him going with that 5-HTP Bonigut blend. And he got better. Now we start to wait for lab results but yeah—I mean  sometimes we will do some of the quick fix of band-aid situations to fix things, but we still got to work backwards. I guess to answer these questions uh—should we answer the question about the cancer question here or shall we just make a whole show on the future?

Dr. Justin Marchegiani: Yeah. We’ll do a whole show on that. I’ll get some experts on. I got Dr. David Jocker is coming next month as well. He was in the truth about cancer series. And we’ll go on ketogenic diets and we’ll talk more about therapeutic ways to address cancer outside of just the natural chemotherapy. So we’ll hold that one that—we need more time for that.

Evan Brand: Yeah. Agreed. Uh—Samuel asked, “What is the tapping technique? Can you show us? Well since most of our audiences are gonna be audio listeners we’re not gonna take up the air time to show you the technique, but the best resources—EFT (Evan-Frank-Tom) EFT.mercola.com and you can just view the different acupressure meridians that you’re gonna tap. But then also, you’re gonna learn about the affirmations that you can use for emotional freedom technique and that’s something Justin and I use all the time.

Dr. Justin Marchegiani: I think it’s helpful. I’m—I’m gonna just give it 15 seconds of airtime here, so—just—I do two hands coz it’s adding it’s more efficient. But you just tap the  inners part of the eyebrow, the outer parts of the eyebrow, under the eyes, I do under the nose, and the bottom part of the chin the same time. And then I do both collarbones. So I do this, and you can go top of the head and tap midline. So I do two hands coz I just feel like you get more stimulation. So I go here, and I’m just thinking about whatever is pissing me off, my wife, I just think about it.

Evan Brand: Haha

Dr. Justin Marchegiani: I kinda give it a number. So if I’m a t like 6/10 regarding irritation, I just think about it. Whatever that issue is, whether it’s like, you know, the person driving  in front of me is so slow  or whatever. And I try to knock that 6 out of 10 so that 10 is the worst.  6 is like 60% to being at the worst. I try to knock it down to a4 to a 3. And so every round—every 2 rounds or so, you kinda just check back in and see if you knock it down. And you go as you kinda knock everything down to a 3.

Evan Brand: Yeah. And we have—I—I start at the top of the crown which I usually like—many ways—

Dr. Justin Marchegiani: You can do that. You can start there, you can end there.

Evan Brand: Now do you do the sides? I know Mercola, he’s big on the side of rib cage under the armpit.

Dr. Justin Marchegiani: Yeah. I do that, too, sometimes. It’s just wasn’t good for a video.

Evan Brand: Yeah. So you criss cross?

Dr. Justin Marchegiani: Yeah. I do two at the same time just coz it’s stimulation.

Evan Brand: No. I mean you criss cross your arms so the underarm’s like this. I do like a monkey.

Dr. Justin Marchegiani: Haha

Evan Brand: And then—and then finish with the wrist. I typically finished by tapping the insides of the wrist together then doing the affirmations. So even though I’m angry, or even though I’m anxious, I deeply love and accept myself. But you gotta say the affirmation verbally. I tell people if you can, if you’re just embarrassed, then don’t do it. But why be embarrassed? Nobody—nobody is paying that much attention to you.

Dr. Justin Marchegiani: Yeah. That depends, too. Like you can do this stuff, and you can kinda say like if you’re at—let’s say, if you’re lying in bed and you’re just really stewing on something and your wife’s next to you and you don’t wanna wake her up, then you can just kinda think it in your head. And then you can just, you know, do the affirmations, tap like this.  And then you can tap here, and think about the issues.

I like them to end, though, with a positive thing. So you can end with something positive. So then I just go into like, “What is it that I want to manifest?” So I’m going into right there. I’m thinking about whatever I’m gonna try to create or produce in my life, I just tap it while I’m thinking about it. And the whole idea of tapping is you’re just stimulating various meridian systems that have been mapped out via acupuncture system for thousands of years. And really what it’s doing is it’s neutralizing the negative response that’s stored in the limbic system or in that subconscious of your—more in the psychological side of it. And you’re trying to kinda rewire it so you can get a good pattern there instead. So then, naturally that reflux is to go back to the better thing and not to the negative thing.

Evan Brand: So if you do affirmation about the bad part, would you do like an affirmation about the bad part and an affirmation for a positive?

Dr. Justin Marchegiani: Yes. So I start off with the negative and just try to lessen—lessen it first.

Evan Brand: Yeah.

Dr. Justin Marchegiani: Coz if you’re—feeling negative, it’s really hard to be positive when you’re negative so I try to decrease the negative to about a three. And then I go into the positive because then, you are in a better place to deal with the positive, right? It’s kinda like when someone tells you to relax and you’re pissed off, like relax, calm down. You just wanna punch him, right? Like, “No, I’m too wound up, come on.”

So I wanna get that dialed in and then now I’m relaxed, now I can rewire it and create some positive things.

Evan Brand: I like it. I like it.

Dr. Justin Marchegiani: So calm down first, and then work on manifestation.

Evan Brand: Should we answer a couple of more questions here?

Dr. Justin Marchegiani: Yeah. Let’s hit it, man. Let’s hit it.

Evan Brand: Solam asked, “How long does it take to heal hypochloridia?”

Dr. Justin Marchegiani: It totally depends, right? If you have emotional stressors that are unresolved ore you’re eating foods that are incredibly inflammatory, maybe never. But if you’re making the root causal changes and your managing your stress, and you’re fixing the underlying gut stuff, I would say within 3 to 6 months, you have a really good chance of not needing hydrochloric acid to digest your food. But again, everyone is different. A longer—the longer the issues been going on, the more severe the infections, and the more infections that are layered in there, I’d say longer, up to a year, at least.

Evan Brand: Yeah. I’ll just have my two cents to that, too. If you had a previous history of a prescription, as a blocker’s proton pump inher—inhibitors are now it’s open to counter like the Xanax or the Toms, or anything like that, or—

Dr. Justin Marchegiani: Yup.

Evan Brand: Or if you’ve had H. pylori which we’ve chatted about many times, then I would say it may lengthen that time, too, to fix that stomach acid issue.

Dr. Justin Marchegiani: The longer that gut’s has been worn down, the more the immune system is revved up like you get patients are just supersensitive to every little thing. Like I can’t even put in an enzyme, I can’t even put in our apple cider vinegar or lemon juice or the smallest fermented food sets them off. It’s really hard and you’re looking at a couple of years to really dive into it because the immune system is so revved up and it’s so ready to attack the smallest invader that it’s so hard to put things into help and heal it because it’s looking at everything as a foe not a friend.

Evan Brand: Right. We really, really have the baby step in those cases so that’s why—

Dr. Justin Marchegiani: Totally. Yeah. I mean, just like you heal, with you know, food is medicine there, you go really slow and you do lots of things in broth form, in soup form so it’s – so it is so palatable. There is very little digestion that has to happen. And typically one supplement at a time and one nutrient at a time, titrate up from low to high. Even if it’s something that they can handle, if they go high dose, off the bat,   their immune system just freaks out.

Evan Brand: Well I wanna hit on something you just mentioned which is if we’re talking 1 to 2 years, it takes extreme patient—extreme patience for patients and clinicians because for us, that is a very intensive case for us to take on.

Dr. Justin Marchegiani: Totally.

Evan Brand: And you know, maybe this is to toot our own horns, maybe it’s just calling out the obvious that we do take the time, you know, with people we’re working  with. Sometimes it maybe 30-45 even an hour-long call for a follow-up just to take these baby steps. Whereas, let’s jus say some of the clinicians that we’ve seen out there, it’s too cookie-cutter approach and they don’t have the mental bandwidth or capacity for empathy to baby step this people.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So it’s here’s your cookie-cutter protocol, good luck.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Where with us, we’ve really, really, really gonna get super details.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And so this is why if you go and you buy like a leaky gut online program or some other type of program, and you get limited results and you get to us, we’re not gonna be surprised if you suffered through that, and you didn’t get a good result. Because at the end of the day, that’s why  Justin and I haven’t created  online courses at this point because it’s—it’s hard for us to sleep at night thinking that we’ve created a program that’s too cookie-cutter. We’ve really got to figure out a way that we’re gonna be able to work in all the minutiae and the small details and the variations—variation A, B and C, D for different people.

Dr. Justin Marchegiani: Yeah.

Evan Brand: So if someone uh—packages something up all beautiful and says, “Oh, it’s $297 and all your problems are gonna be healed.” Uh—please be a little bit skeptical  of that.

Dr. Justin Marchegiani: I agree. And I’ve talked to you about a patient that I had today that email in that was dropping out of care. And we try to always set realistic expectations. This person just had her labs reviewed a month or two ago, and had multiple parasitic infections, severe adrenal dysfunction, HPA axis dysfunction, and then a lot of issues on her organic tests. Uh— detoxification issues, mitochondrial issues, and we just started with simple adrenal support, made diet and lifestyle changes and she had some— some side-effects so we try to cut things down, go slower. And we’re gonna kinda reconvene and work on supporting detoxification, but person had dropped out. Now, the problem is, to have expectations that things will work off the bat when so many things are wrong like that, expectations are incorrect. So  a lot of people they have preconceived notions even if you spell it out to them and you let them know, “Here’s where we’re at now, here’s where we’re going.” They forget because they—they want it done now. And they think because things didn’t work in that initial uhm—in that initial experience, that there is no way to fix it. So continuing to harp on patients in managing their expectations, even though they have a lot of stuff they’re projecting from past failures, we kinda have to get through it. Make sure expectations are real and that make sure they know, “Hey, here’s where we’re going now. Here’s where we’re going next.” These things ahead that may have to be dealt with for us to really see great changes.

Evan Brand: Yup. Well said. We got another question here.

Dr. Justin Marchegiani: Let’s hit ‘em.

Evan Brand: Let’s hit Steve’s question. After all GI infections are eradicated, how long does it take the gut to fully heal? All my infections are gone, but I’m still dealing with IBS, leaky gut and issues after H. pylori.” I’m gonna hit on this first Dr. Justin Marchegiani, if you don’t mind.

Dr. Justin Marchegiani: Yup. I know you’re gonna say it, by the way.

Evan Brand: Okay. So – haha if—

Dr. Justin Marchegiani: If you say it—If you say it, I’ll—I’ll tell you that.

Evan Brand: Okay. Alright. Please. Alright. So here’s what I’m gonna say. You say all your infections are gone, but you’re still dealing with IBS, leaky gut, and issues, I would like to know what test was this that says all your infections are gone because I bet all of your infections are not gone.

Dr. Justin Marchegiani: Yes! Whoo! I knew it. Yeah. You’re totally right.

Evan Brand: Haha

Dr. Justin Marchegiani: Yeah. You’re totally right. And then also, just making sure that you have the digestive nutrients on board to help heal the gut lining and the digestive support to break down the food and then I would make the food more—more palatable right now. I’d be looking more at the GAPS or an SCD or more of a soup or broth approach that makes the food really easy to take in. No raw veggies, uhm—try to keep it really palatable so the body can access it without much stress.

Evan Brand: Alright. So the beauty of the Internet, Stevie says—Stevie replied and he says, “DRG” Well, uhm— Justin–

Dr. Justin Marchegiani: It’s missing a lot of them. It’s missing a lot. You gotta do the DRG with the GI map. I a—I never do the DRG by itself for the most part—always both. You gotta do both.

Evan Brand: Yup.

Dr. Justin Marchegiani: And if there’s still an issue with the DRG and the GI MAP, I want them go for the  41 side-by-side.

Evan Brand: Yup. Agreed. So, Stevie, not that—you know, we’re not diagnosing you. That’s not what these calls are for. But, hey, Justin and I have seen a lot of false negatives with DRG and some other test out there. So potentially some stuff going on. And I would like to add a couple of points about like the—the issues, the leaky gut type stuff. You know, make sure you are doing some of the easy supports, too. You know, chamomile is great. You can do chamomile in a supplemental form. You’ve got chamomile teas, uhm—you’ve got L- glutamine. So there are some leaky gut supplements that why your til—still trying to figure stuff out, you can still be taking support of nutrients in the meantime while waiting for retest.

Dr. Justin Marchegiani: Absolutely. Totally. Let’s hit  the uh—last question there by—E Center Riley. See here, just diagnosed with Hashimoto’s, TPO and TGB bodies, 465 is that high? Eliminated the foods, gluten, dairy, soy, balance in blood sugar, hard with 5 kids. What should I focus on next? So 465 is definitely high. The LabCorp reference range for TPO is 34. Anything 34 above is considered positive—I think it’s above 34. 34 below is considered positive. And anything about 20, for me, I considered to be subclinical. So that is high. Anything above or around 500 is definitely high. I’ve seen patients at 2000, though. I’ve seen patients that go from 2000 to below a 100. Now, my goal is to get people—If I were you, I’d like to see a 70 to 80% reduction in that. Again, maybe you were higher before you made those changes. So I’m not sure if it was  gluten, dairy, soy. That stuff was cut out and then you saw the drop. But either way, uhm—getting enough selenium in there, 400 micrograms of selenium, addressing the underlying infections, things like H. pylori, Blasto and Yersinia can be coming to increase the antibodies. And then making sure the adrenals are looked at. There’s a strong adrenal-thyroid connection and a lot of people who have thyroid issues also have adrenal issues. And remember, TPO is a microsomal or essentially it’s uh—intracellular microsomal antibody that helps bind the thyroid hormone together. So if you’re making antibodies to that, it’s gonna prevent that thyroid hormone that I—Iodination process from occurring. So making sure we have the adrenal support there because the adrenals help produce cortisol. Cortisol is an anti-inflammatory that’s gonna help with the inflammation. And with the TPO there uhm—you could potentially have increase in hydrogen peroxide, especially if there’s small amounts of iodine getting in there. So get them the selenium will help neutralize that hydrogen peroxide into H20. High quality H20 which is uh—not gonna be as inflammatory.

Evan Brand: Well said. Yeah. And so uhm—Isabella Wentz, I just did podcast with her a couple of weeks ago. Actually that was my last uploaded episode. And uhm—we’re talking about bacterial infections, too. So you mentioned some of the parasites and she’s seen the same thing the parasite but also the bacteria. The Klebsiella, the Citrobacter, and all these autoimmune triggers has been bad guys for uh—these Hashimoto’s situations and these antibodies, so—

Dr. Justin Marchegiani: Yeah.

Dr. Justin Marchegiani: So, look for the bacteria, too, and you can definitely fix this stuff and you can make significant progress.

Dr. Justin Marchegiani: Absolutely. I mean one person here, wildlab access, “How do you test for various enzymes?”Number one, if you have gut stress, you probably have low hydrochloric acid. And if you have low hydrochloric acid, you probably have low enzymes. Why? Because hydrochloric acid is important for acts of—for converting pepsinogen to pepsin which is the proteolytic enzyme. Hydrochloric acid lowers the acidity of the chyme, which is the mixed up food in the intestine. That inten—that food that chyme that goes into the small intestine which the acidity then triggers the pancreas to make bicarbonate, it also triggers CCK that then caused that the gallbladder to produce bile that also stimulates the pancreas to make light based trypsin and chymotrypsin and all the enzymes that come down. So if you have enzyme issues, you also have hydrochloric acid issues, but we can also assess it by looking at enzyme markers, like elastase, too, which will uhm—look at that in the DRG or the GI MAP test.

Evan Brand: You better get that frog out.

Dr. Justin Marchegiani: Frog out. It just attacked me, man. I’m like, Ugh—

Evan Brand: Alright.

Dr. Justin Marchegiani: My water—so uh—yeah. Elastase, I think it’s elastase 1 is the enzyme marker we typically look at for uhm— low enzymes. But typically, just assuming that we have digestive stress, let’s assume it for sure.

Evan Brand: Yeah. I mean that’s the same—the same answer that I would say for the leaky gut. I had people say, “Oh, can you test me for leaky gut?”  It’s like, “Yeah. We can go to Cyrex and spend 500 bucks if you want to, but based on your symptoms, I guarantee there’s intestinal permeability. You’ve got XYZ. And we can—we don’t need to spend the 500 bucks on that test. Save your money for the organic acids, your comprehensive stool panels, the GPL-TOX, maybe heavy metal testing. Save your money for that stuff that you can’t really guess on.

Dr. Justin Marchegiani: Yeah. Absolutely. I agree, man. Well, anything else you wanna hit off the bat here? I mean I think—I had some really good successes last week, too, with some patients that had chronic pain, chronic mood, chronic energy, hair loss. And I mean—just really simple things. We—we fix their hormones, this person has autoimmune thyroid, uhm—hypothyroid as well. T3 was super low, it was uh– T4 to T3 conversion issue, dysregulated cortisol. They had a lot of malabsorption and they had a couple of infections and we just—we just took them down the map. An then just everything first time around, uhm—just knocked in place. I mean it’s like you swing the bat once and it’s connected. It’s gone. Those were the patients where its like, “It’s just so rewarding coz it’s just—it’s easy” And then you have  some patients where it’s a lot more trial and error and digging in. So it’s nice to have those home runs every now and then.

Evan Brand: Oh, man. I—so I had a home run earlier with this guy that I got off the phone with name Dion. And he was on an inhaler. An asthma inhaler.

Dr. Justin Marchegiani: Yeah.

Evan Brand: And also I believe he was taking uh—allergy medication, like a prescription allergy medication.

Dr. Justin Marchegiani: Yeah.

Evan Brand: Maybe it was one or the other. He alternated or he was on the inhaler something. But he was on prescriptions for allergies. And all we did is we cleaned up the diet, we’ve addressed some gut infections. He had candida and I believe a couple bacterial infections. I don’t believe he had parasites. I have to look back. But I remember a couple of infections, fix the gut, uh—supported adrenal’s basic adrenal support, some adaptogens. And I talked with him today and he said, “Evan, I’ve not used my medication in the last six weeks. And everything is blooming here right now. All the trees and plants and everything are blooming and normally, I’m debilitated. He said, “I’m completely fine.”

Dr. Justin Marchegiani: Isn’t that awesome?

Evan Brand: How in the world just by working on the gut and adrenals am I not allergic to the environment anymore? It’s just like, “Oh, it makes me feel so good.”

Dr. Justin Marchegiani: I see that all the time, too. And hydrochloric acid is one of those things that’s really great with allergies, too. You notice that?

Evan Brand: Ain’t that weird? I mean since digestive enzymes, I told him, I said, “Man, we’ve gotta keep up digestive enzymes.” And then actually I am gonna send him a bottle of some of the like natural herbal anti-histamines, just in case. Because he started sneezing on the phone. I’m like, “Whoa, maybe you’re not all the way out of the water yet. Have this on hand, in case you need it.” So the coresatin in, the rutin, some of those–

Dr. Justin Marchegiani: Hesperetin

Evan Brand: Yeah.

Dr. Justin Marchegiani: The things I love for allergies: number one, just really get a good air filter. I used one by Advanced Air. You can see that at justinhealth.com/shop Look at the approved products. I like it. It’s good. Uhm—and then your natural anti-histamine degranulating compounds. In my product, Aller Clear. Stinging Nettle, coresatin, and then you’re gonna have like some vitamin C in that, some potassium bicarb as well. So those are really good. And you can go up to eat. The nice thing about it, just not gonna be drowsy. So you can get that allergy support without getting the drowsiness and then really make sure the diet is anti-inflammatory. Up the hydrochloric acid because HDL is really important with low—with allergy. It’s gonna make a big difference.

Evan Brand: Yup, Yup.

Dr. Justin Marchegiani: Ginger. Ginger is phenomenal, too, for allergies. Really good.

Evan Brand: I love ginger. So it’s a great nutrient. I’d do teas, ginger kombucha, there’s so much you can do with ginger.

Dr. Justin Marchegiani: Oh, yeah. By the way, right after this, I’ve got a new grill. So I’m gonna go out, I’m gonna grill some grass-fed hotdogs, right? And then I’ve got some sauerkraut with mustard. And I’ve got a nice ginger kombucha, I’m gonna open up. So I’m really excited for my lunch break today.

Evan Brand: Nice. What kind of grill? Is that one of those  pellet jobs?

Dr. Justin Marchegiani: I actually—I got a new Webber just because it’s—it’s—my other one was 10 years old. And then the knobs are starting to go. So I got a nice, little Webber Spirit. So it’s great. It’s got three burners. Love it. And uhm—I got a smoker that I use sometimes for ribs on the weekend just like a 4-hour job. So it’s good to have a day or an afternoon to kinda be at home to enjoy that one but—Yeah. So love my grilling. Try not to get things charred. Try to keep the heterocyclic amines and the polyaromatic hydrocarbons to a minimum.

Evan Brand: Agreed. Agreed, man. Cool. Well I don’t have one on my end.

Dr. Justin Marchegiani: You wanna have a share?

Evan Brand: No.

Dr. Justin Marchegiani: Hope you guys are liking these calls here. We wanna do more. We wanna connect with the listeners. Our purpose really is to serve and help people get their health back. If people want more feedback, or want more kinda like rolling up the sleeves and specifically diving into your case, go to notjustpaleo.com or justinhealth.com, click on the schedule buttons. And we are here to help you out. Evan, anything else, man?

Evan Brand: That’s it. Have a great day people, drink clean water, get rest, reduce stress, be grateful. It’s gonna go a long way.

Dr. Justin Marchegiani: And people on Facebook, I’m hoping we can get Evan on here soon. We gotta just  figure that out. So hopefully, soon we’ll do that. So Evan, great chatting with you, man. We’ll talk soon.

Evan Brand: Take Care. Bye.

Dr. Justin Marchegiani: Bye.









Enzymes and digestive support – Dr. J and Evan Live Podcast #127

Dr. Justin Marchegiani and Evan Brand discuss about enzyme, its uses to the body, as well as its impact on digestion and overall health. Listen to them as they go into the enzyme mechanism related to gut issues such as infections and heartburn.

Know about the acidity levels that may have positive or negative effects to one’s digestion. Gain valuable insights regarding the different topics asked by the listeners which include hiatal hernia, PPIs, and antibiotics. And learn more as these functional medicine experts share their knowledge about diet and supplements that have huge effects on enzyme production and stimulation.

In this episode, we cover:

2:13   Enzyme Production

6:10   Gut issues and heart burn

12:30   Symptoms involved with enzyme and acid issues

24:05   Hydrochloric Acid (HCl)

30:05   Types of enzymes

35:48   Antibiotics and gut health






Dr. Justin Marchegiani: Hey there! It’s Dr. J and Evan today. We got an awesome podcast. It’s a great Friday. We are live, too. So anyone’s that tuning in and wants to get some questions asked and/or answered, we are stoked to be able to do that. Today’s topic is gonna be on enzymes and how they can be used therapeutically to help with digestion and to overall improve your health. Evan, what’s going on, man? Happy Friday.

Evan Brand: Happy Friday! It’s beautiful here, the trees are blooming. It is freezing, though. We went from 70° to like 30° so – uhm, hopefully spring is coming because I’m ready to get outside again as soon as possible and go for an extended distance hike.

Dr. Justin Marchegiani: Got it. And people on Facebook here, if you’re not hearing Evan , do your best to head over to the YouTube channel. YouTube.com/justinhealth and click on the live view so that you can see Evan’s beautiful mug staring back at you and get your questions answered. I’ll try to be able to answer questions on Facebook as well as YouTube. So feel free and ask.

Evan Brand: Perfect. So enzymes – where should we start? I mean this is the importance of health; this is the – this is important for longevity; this is important for preventing or reversing disease because you’ve got to build a breakdown of foods with enzymes to be able to actually absorb the nutrients. Time and time again, you and I run organic acids panels on people where we look at amino acid metabolites and we look at these other biomarkers where we find that people are just not digesting their food and they’re not absorbing or assimilating any of their nutrients despite them spending hundreds of dollars a month on food, and organic food. Or they are on AIP diet, and they’re buying grass-fed beef and organic veggies but yet, they’ve got all these symptoms because they have low enzymes. So they could have hormonal imbalances; they could have fatigue; they can have excessive hunger; they could have sugar cravings and carb cravings all which could be tied into this enzyme deficiency because they’re just not breaking down their food; they’re stressed; they’re not chewing their food well. We’re kinda break all this down today.

Dr. Justin Marchegiani: Absolutely. I love that. So off the bat, let’s talk about how your body can actually make an active enzymes first. I think that’s a really important first step. So enzymes are primarily gonna be stimulated through the digestive processes and primarily the parasympathetic nervous system. So the more your nervous system is parasympathetic, right? That’s the – the rest in digest. The more you’re gonna have a nice low pH in your stomach. You’re gonna have gastrin stimulated. All these gastric juices uhm – coming about. That’s gonna lower the pH coz a lot of enzymes are actually pH driven. So if we don’t hit that first domino of parasympathetic nervous system stimulate the nice low pH and the nice low pH is from hydrochloric acid. Hydrochloric acid kinda also has the sterilising effects. So if you get some bad, kinda junkie food in there, it’s gonna have like an effective taking maybe you some bleach and putting it on a public pit. It’s gonna help clean it up. So it’s gonna be more sterile environment. So think of hydrochloric acid as like a bleach in your tummy. And also activates the proteolytic enzymes. It starts with pepsin, it takes pesinogen to pepsin. So it gets the digestive enzymes going. And that nice, low pH, all that food gets mixed up with the hydrochloric acid and eventually goes down in your small intestine at least as chyme. And then it stimulates the pancreas to produce more enzymes in the gallbladder to produce more bile which will help with fat. So that’s kinda first domino reaction and it starts with the parasympathetic nervous system response, and it starts with having good hydrochloric acid levels. Now, one thing to talk about here, “How can we stimulate our own juices?” Number one, chewing your food well is gonna be super important. Making sure you really chew, one chew per tooth is a pretty good rule of thumb. Number two is making sure you’re in parasympathetic state – not eating and not being on the go or eating when you’re in the car. Have a good relaxation kind of state. Number three, making sure you’re hydrated coz a lot of the digestive juices come from the liquids that you eat. And then number four, not consuming water for the sake of hydrating while you are eating.   The more you consume water while you’re eating, think about it- water has got a pH of 7. 7 is going to take the pH in your gut at 2 and bring it up close to the 7. So these enzymes are pH driven. So the lower the pH, the more the enzymes are activated the more water you drink in the meal, the more you dilute the enzymes that are already there, the more you raise the pH and you deactivate future enzymes from being produced. What do you think, Evan?

Evan Brand: Yeah. So people wanna know the number about the stomach. It is very, very acidic. 1.5 sometimes 1.2 to 3 is the range of the pH. I mean this is so intensely acidic that if you opened up that HCl out of your stomach and put it on your shoe, it would melt your shoe into piece.

Dr. Justin Marchegiani: Absolutely.

Evan Brand:  You’ve gotta have that. And I wanna just repeat that because you said it well, but in order to activate pepsin in your other enzymes to break down the protein, you’ve got have an acidic enough stomach. You’ve gotta have enough HCl production.

Dr. Justin Marchegiani: Absolutely.

Evan Brand: And so you’ve got have parietal cells in there that are making the HCl. But if you’re in sympathetic fight or flight mode because your body thinks you’re running from a bear even though it’s just running from email, or you’ve got a bad boss, or you’ve just got some bad news, or you’re eating during a meeting, or you’re eating at your work desk. You know these are all things that are not going to trigger that –

Dr. Justin Marchegiani: Totally.

Evan Brand: You’ll be setting yourself up for you know, tummy trouble. And we can talk about some of the implications of what happens if you have this hypocholorydia state which is a low stomach acid state that basically set you up for infections and things like that which we’ll get into.

Dr. Justin Marchegiani: And again, we got questions coming Facebook and I apologize. People on Facebook are only seeing one side of the conversation here. But – Hey, Steve, how you doing? Off the bat with the gastric ulcer situation. If people have an ulceration or have gut lining issues in the stomach, one of the first things we do off the bat, if we know that history is present, we’re gonna use gut healing and soothing nutrients first. We’re gonna use bone broth, we’re gonna use aloes, slippery elm,  deglycyrrhized liquorice, L-glutamine and we’ll kinda coat that stomach there. We’ll make sure the food is well broken down. We may even focus more on the GAPS kind of approach. And add more liquid soups that are really easy and palatable. And we may focus more on enzymes first. Now depending on how someone is doing, how sensitive the gut is can be a good measure of how the gut’s healing. That’s a good sign. So you can start with like a 6 to an 8 to a quarter of the teaspoon of apple cider vinegar with food. Now if you’re gonna add any acids in, you can start with light acid such as Apple cider vinegar, and/or uhm – just plain old organic lemon juice and do it with food because if the stomach is empty, it’s like someone touching your raw sunburnt skin. It is gonna be more sensitive. Put a little food in there, do a nice gentle, very low dose of acetic acid, whether it’ in uhm – apple cider vinegar or citric acid in the lemon. That is a really good step. Quarter of the teaspoon and upwards and gradually work your way up. If that’s good, once you get a full tablespoon and have no problem with food, we can transition you to an actual hydrochloric acid tablet with pepsin. But in the interim, healing, soothing nutrients, and then we taper. We focus more on the enzymes in the HCl because they are less abrasive.

Evan Brand: Let’s back up a bit. Let’s talk about symptoms people may be experiencing if they need enzymes or if they are in this hypochlorydia, low stomach acid state. So I would say, any type of burping or gas after eating, that tells us you’re not breaking foods down.

Dr. Justin Marchegiani: Huge.

Evan Brand: If you’re a vegetarian or a vegan in the past, a lot of times people go vegetarian or vegan because they say they’ve lost the taste for meat. But in many cases, that just because they don’t have enough stomach acid to digest meat.

Dr. Justin Marchegiani: Exactly.

Evan Brand: And so meat is bad for you, but it’s not. Heartburn – a lot of times people have heartburn but it’s actually too low stomach acid not too much. You’ve got that valve at the bottom of the stomach and it’s kinda regulator. And if your food is not broken down, your body’s smart, it doesn’t want undigested food in the intestines, so if it can’t go down, it’s gonna leak in one place which is up. What about the uh – lower esophageal sphincter? Can you talk about that maybe from like a chiropractic perspective? About how that valve can get stuck open. I mean, can adjustments and massages or stuff help that? Or is that more internal work has to be done?

Dr. Justin Marchegiani: Yeah. I mean you have different issues with the various sphincters that go from the esophagus into the stomach. And then obviously, the stomach into – hold on, one sec. I’ve got a little _ right here. I apologize for that. Okay, so regarding that – you have different sphincters that go from the stomach to the small intestine,  from the small intestine to the uh – large intestine. And obviously from the esophagus into the stomach. So the key elements here is we have to make sure the first domino is gonna be the esophagus to the stomach, right? If we don’t have enough acidity, what happens is that esophageal sphincter is they open. So this is one of the major reasons why stomach acid actually helps a lot of people with heartburn. It helps two ways. The esophageal sphincter gets tighten when there is enough acidity. And then number two, food will rot and putrefy and ferments and organic acids will rise up from the food. So if there’s not enough acidity, initially, that esophageal sphincter may stay open, food will rot and then those acids will rise and burn the esophagus. So 2 mechanisms: tightening of the sphincter and the breaking down of the food. If we don’t do that, it rots. So that’s step number one. Step number two, food goes from the stomach to the small intestine. If we don’t have enough acidity, then we’re not gonna trigger the bicarb release from the pancreas when it goes from the stomach to the small intestine. We’re not gonna trigger the gallbladder and we’re not gonna trigger the uhm – the bile salts. Number three, it goes from the small intestine to the large intestine. If we have dysbiosis and low stomach acid and low enzyme environments, we can have ileocecal valve patency where this  is kinda the first mechanism of SIBO or the bacteria from the colon will start migrating its way back up to the small intestine and then we start getting all kinds of extra methane and hydrogen gas is increasing. And that’s gonna create more malabsorption, more diarrhea, more constipation, more of those IBS kinda sequela. And then –

Evan Brand: I wanted to ask you one thing. I know we’re – we’re a bit biased because of the people that are coming to us typically they’ve been to 5, or 10, or 20 different practitioners –

Dr. Justin Marchegiani: Yeah.

Evan Brand: Before they get to us which is mind blowing and it’s an honor. What percent of people have a low enzyme state, low stomach acid state, therefore potentially SIBO state? I mean, you and I see bacterial infections. I’d almost say it’s 9/10. But I wanted to see what your number is.

Dr. Justin Marchegiani: Yeah. So how many people 9/10 here or out of 10 here do we have bacterial infections? I would say at least half of some type of digestive issue minimum. Uhm – I would say out of the general public, I would say the people that see us I would say a 100% have some level of a gut issue. Even if someone doesn’t know it because – people come, let’s say they don’t have a gut issue, let’s say it’s hormonally driven. If it’s a female, it’s gonna be PMS or mood issues or fog. If it’s a male, it’s gonna be uhm – energy, focus, endurance, exercise, muscle mass, low libido. Again, those issues can be affected by the gut and a couple different mechanisms. And kinda tying it back to enzymes, we always go on our diets here. But if you have enough enzymes and digestive capacity, all the nutrients that make up all the brain chemicals which help us focus and think and deal with stress, also the nutrients that help become our hormones. So the cholesterol and the essential fatty acids they’re gonna become the precursors to our cortisol and our sex steroids. So if we have any digestive issues, any of that could be thwarted by low stomach acid and enzymes. We’re not gonna have the building blocks that we need to – to build a healthy chemicals to help us feel good, deal with stress and inflammation, help rebuild our body.

Evan Brand: Yeah. Just to zoom back out, this cascade, this domino effect you’ re discussing could all happen from you scrolling on Facebook while you’re sitting down to eat your lunch.

Dr. Justin Marchegiani: Totally.

Evan Brand: And that’s the important part. So I wanna go back and just mention a few more symptoms of people that you have a need for enzymes and/or increased stomach acid. If you got undigested food in your stool, that’s an easy one. If your stool is floating, that’s an easy one because we know therefore, that the bile is likely not getting secreted potentially due to a low fat or too low-fat diet. So therefore, you’re gonna have that issue. Uh – also fingernails. So Justin and I, we talk a lot about fingernails. So if you’ve got chipping, peeling, very brittle fingernails, you’ve got ridges on the nails, that tells us that digestion is not good. You’re not getting these trace minerals from your food. Uhm – and then last one, we could just say anemia, right? Because if somebody’s got low iron or ferritin levels, we know that they’re eating grass-fed beef or bison or elk and all these delicious foods, but you’re not  rice and help knowledge delicious foods but you’re not cleaving off the iron and so you gotta have a lot of acid to do that.

Dr. Justin Marchegiani: 100%. Couple of just to kinda piggy back on that, you have the fingernail issue, if you run your finger across the other finger, across the arch of it, if you have that’s relatively, you may see some tiny, tiny lines but when you run on your finger, it should be smooth. You shouldn’t see any white spots or little speckles on the finger. That’s a sign of zinc deficiency. Your nail should be relatively strong. If you push it straight down on an axial low position, it shouldn’t really bend. It should stay pretty straight, pretty strong. People that have issues with this, their nails will start to peel. Those are to be more brittle and weak. You’ll start to see vertical ridge and white spots. That’s gonna be your first kind of sign that you’re not quite digesting protein, fat  and obviously ionising your minerals especially zinc. That’s number one.  Number two, in females, it’s super common, it’s called uhm – keratosis pilaris. So if you look on the females, back in their arm, the tricep here, like this are of the tricep, you’re gonna see this like little dots, like this reddish kinda spots. And this is called uh – Keratosis Pilaris, typically from essential fatty acid deficiencies. And a lot of times if you don’t have enough hydrochloric acid and enzymes, that will show up. So you – you know, you walk through airports or see lots of people, you’re gonna see that commonly on a lot of females’ arms, especially birth control pills can exacerbate it more.

Evan Brand: Why?

Dr. Justin Marchegiani: Uh – because it affects digestion.

Evan Brand: Oh – yeah. And my wife for example –

Dr. Justin Marchegiani: And it affects nutrient deficiencies, too. B vitamins, minerals and such.

Evan Brand: So I’ve got two personal anecdotes to what you’re talking about. So when you first looked at me, you say, “Evan, you’ve got a parasite.”

Dr. Justin Marchegiani: Uh-hmm.

Evan Brand: And you said I had two parasites and my nails were terrible. Now they start to get much better because I’ve cleared the infections and now I’m supplementing with enzymes like – you know, it’s water. I love them. I’d take them with every meal. Uh – but also, my wife, when she was on birth control pill as a teenager, she had major Keratosis Pilaris on the back of her arm.

Dr. Justin Marchegiani: Huge.

Evan Brand: It was crazy. I mean –  massive amount. And she thought that, “Oh, my mom had it, so I should have it.” No, that’s not the case. And so now, with the fish oil –high potency fish oil, the enzymes and then making sure the gut’s healthy, it’s gone and it’s amazing.

Dr. Justin Marchegiani: Yeah. Typically, the birth control pills gonna affect the pH uh –in the – in the intestines primarily the urinary track. That’s one the big things you see with females on the birth control pill. You see increase in yeast infection. They’re gonna affect pH and that vaginal kind of environment. and obviously it can have an effect in the gut, too. So the more you uhm – negative competing opportunistic microbes to kinda  invade in there, they’re gonna the shift the environment to be more favourable to them. And that’s gonna take away from the digestion capacity. And the more your digestion is down, harder  to breakdown those proteins and fats and ionised minerals. And then you can start getting those deficiencies. That’s why B vitamins, and minerals, and essential fats one of the first deficiency you’ll see on birth-control pill. So tying it back in here, enzymes are super important. Couple of questions from uh – YouTube, pH – like the whole idea pH, I mentioned, people say you wanna be alkaline, the question is where? Where do you wanna be alkaline, right?  With the stomach, you wanna be very acidic. In the stomach or in the small intestine, you wanna start becoming alkaline again. As you go back on the colon, you’ll start to be a little more acidic. The urine typically is gonna be a little bit more acidic coz you’re putting more acidic waste out through it. Uhm – you’re gonna have bicarbonate that’s gonna bind with uhm – CO2 in the blood to help rid of the CO2. So you’re breathing out acid via the CO2 and making bicarbonate in the blood. So a lot of pH regulatory systems that are happening. The biggest thing that’s gonna affect pH is inflammation. Inflammation is gonna have an effect on pH a hundred to a thousand times greater than your diet. Uhm – you’ll see –

Evan Brand: Say that again.

Dr. Justin Marchegiani: Yeah. Your pH is gonna have about a 100 to a 1000 times more of an effect because of inflammation due to your body, not because of your diet. Now you’re diet – you can have inflammatory things in your diet such as grains, excess sugar and trans fat, but again, meat – people meats are acidic, right? About 5 or so on them. 5- 5 ½  on the pH scale which is logarithmic. But grains are 10 times more acidic than, let’s say meat. And if you listen to my podcast it will be coming in a few weeks with Doctor Robert Rakowski part 2. He talks about that apect. That it’s the inflammatory things in our environment that are creating far more acidity than our diet. But again, healthy green, organic vegetables in every meal, you should be totally fine from the pH perspective and then getting some good extra minerals in your multi-support whether it’s magnesium, potassium, calcium. Those extra buffering mineral should – you should be buying.

Evan Brand: Let’s also bring up alkaline water and how big of a scam and ridiculousness it is to do alkaline water if your goal is to have optimal digestion especially people drinking alkaline water. They buy these expensive machines were they’re pumping of 9 or 10 on the pH scale of water.

Dr. Justin Marchegiani: Yeah.

Evan Brand: You’re drinking with the meal. I mean, you’re setting yourself up for failure. Now, could there be some type of therapeutic benefit of alkaline water by itself? I don’t really know maybe you’ve got some advice on that. But for me, I’m gonna go with a good spring water or a good reverse osmosis water with trace minerals back in like you do. I mean, for me, the alkaline water, it’s just been debunked so many different places and it’s not worth even talking much more about.

Dr. Justin Marchegiani: Yeah. I’m not a huge fan of alkaline water. The question is anytime  someone sells me an alkaline water, I’d say, “What are the buffering minerals that you use to make it alkaline?” And typically, they’re like, “What?” Coz if you got just a really good clean water, I mean, just adding some good-quality electrolytes or a little pinch of high-quality sea salt with the spectrum of minerals, you’re probably gonna be pretty good and that may raise the pH up a little bit. But I’m not concerned about getting up – you know, having super, super alkaline water. I’m fine with drinking water that’s clean  and filtered. Infuse some minerals back and I will have a little electrolyte solution. I’d put my reverse osmosis water filter, so I’ll put a little bit of minerals in there first thing in the morning. Or I’ll just – I have a little salt shaker there, too. And I’ll get some extra minerals. And that way,  1 to 2 glasses in the morning, one to two big glasses in the afternoon with infused minerals and just salt my with – with good Celtic or like typically like real salt better just for flavour variety. But that’s a good way to get the minerals. Not a huge fan of you know, these crazy expensive water machines that are alkaline. I think the really high-quality filters are better. And uhm – I  like things like Pellegrino and natural sparkling water too because of the extra sulphates that are in there which is so good for detoxification, too.

Evan Brand: Yeah. So, I wanna ask you, chicken or egg question and then we can probably hit some of these YouTube questions about the hiatal hernias and HCL supplementation, all that.

Dr. Justin Marchegiani: Yeah.

Evan Brand: It’s hard to say, did someone get a low enzyme, low HCL state, which then led to undigested food particles, which then were to intestinal permeability or leaky gut, which then set them up for SIBO or parasite infections? Or did the infection come first? Like I told you about yesterday. I had a little four-year old girl that had her stool test back and she  had two parasites. And it’s like – being that young, we would assume that HCL and enzyme production would be pretty good, being a tiny little kid. But, she had tons of rounds of antibiotics. So it’s like chicken or egg. Was it the HCL and enzymes that got low that did set her up? Or was it just the decimation of the flora via about antibiotics that didn’t set her up for infections? Which one do you think it is?

Dr. Justin Marchegiani: Yes. When it comes to infections, there’s a couple of  scenarios how that happens. Number one is your stress. Your immune system is compromised and you get exposed to some infectious debris. And your IgA, your enzymes and hydrochloric acid levels are low and you can’t – you can’t quite – uh, you know, uh – knock it out. It’s just kinda like you leave the drawbridge down in the castle, you’re flying around the Star Trek ship and the force fields are down. So invader can come in, the Klingons can attack, right? Those are my analogies. Now that’s scenario number one. Now scenario number two is you’re relatively healthy and you just get exposed to a large bolus of infectious debris, right? You’re hanging out and you’re drinking some water in Mexico. You’re on the beach in Bali, you’re out in uh – Lake Austin, like I do and maybe someone water comes in your mouth, and you get some GERD, right? So those are the two major scenarios. And it’s – number three is uhm – I would just say food vector, the compromised immune vector.Those are gonna be the two biggest ones. There’s a couple of out there – ones and that’s gonna be the animal vector. You’re just getting exposed or you’re letting your animal lick your face all day, and you’re just not even – you’re not connecting the fact that your cat may have crypto and now you got the crypto infection. Or I’ve seen it with dogs and GERD is super, super common.

Evan Brand: What about this question here about, “Can a hernia cause hypochlorhydria?” What’s your experience from a chiropractic perspective on hiatal hernias? Can you fix those chiropractically? And will that cause low stomach acid?

Dr. Justin Marchegiani: So regarding hiatal hernias, and I just posted a link online for people on YouTube or Facebook that wanna see the full, kinda dual side of it. We only kinda do my side with the technology that we have here. But regarding hiatal hernia, in my opinion, if you’re only fixing a symptom of the hiatal hernia, if you’re doing a chiropractic adjusment for it. Now I think that’s fine because it palliative, it’s natural. You know, what’s the risk to reward? Very little risk, only reward. We just wanna fix the root cause. And typically that’s gonna be getting the inflammation vector away from the intestines.  Once the inflammation is better, the nerves that go to those muscles won’t be sending the inflammatory response that’s creating that tightening. It’s called the viscera somatic reflex. Visceral is organ; somatic is muscle. So the organs and muscles  are on a two-lane nerve highway and the more those nerves are stimulated, it’s like the more you do bicep curl, the bigger your bicep gets, the tighter, tighter it gets, right? The more stimulation that goes to that area that’s like pain, the more it can pull that stomach up above the diaphragm which is based the hiatal hernia.

Evan Brand: Wow.

Dr. Justin Marchegiani:  You pull it down, but then you wanna make sure you get to the root cause. Inflammatory soothing nutrients, fix the infection, fix the ability to digest the food.

Evan Brand: Okay, good. You answer the question. So you can help with physical adjustments of hiatal hernias but you also gotta be working back to the root cause to make sure it doesn’t just pop back.

Dr. Justin Marchegiani: Exactly. That’s the key thing.

Evan Brand: Okay. Here’s another question then. Uhm – “When can you start minimising HCL?”  He’s been taking them for three months. So I guess the question is – is there ever a time where you stop taking them? And I’ll just go ahead and give my two cents first, which is not really. There’s never really an expiration date of when you should uh – minimise HCL. Because if you look at Dr. Jonathan Wright’s book, “Why stomach acid is good for you?”, we look at age. With the Heidelberg test, we see that HCl just drops and drops every year that you get old. Uh – any age past twenty, actually you start reducing HCl. So for me, I consider it the foundation. But what about you?

Dr. Justin Marchegiani: So couple different theories on that. I think hydrocholoric acid is the most under rated supplements in the toolbox for any functional medicine doctor and patient. I think it’s absolutely essential because if you buy a really awesome, organic diet, healthy meat, healthy proteins, healthy fats, and you’re not quite breaking it down fully, well you’re really not gonna be accessing all the nutrients that are in those food. So I think that – from that perspective, it’s a great insurance policy to access your nutrients from your expensive diet already.  Number two, I think it’s something is you get help that you don’t need it all the time but like for instance, I’m heading down to lunch here over at Paris down in Austin. So it’s like I’m doing like let’s say, Friday lunch. I’m really excited about it. I’m gonna bring some hydrochloric acid and some enzymes. Its gonna be some nice little pork chop I’m gonna have there. So we’re gonna up the HCl and enzymes big time. That’s number one. Uh –number two,  if people don’t want to be on it all the time, there are things they can do if they need a little support such as Swedish bitters whether its gentian, or chamomile, or little bit of ginger, can very easily just stimulate your hydrochloric acid levels. Or even just a tablespoon of apple cider vinegar or a little bit of lemon juice can be really stimulatory for the hydrochloric acid. There are ways you can stimulate it naturally. And also, there are studies looking at gastrin. Gastrin is the compound that’s produced in the stomach that actually feeds back to produce hydrochloric acid. And that compound –  that chemical does not decrease as you take hydrochloric acid. So it doesn’t have a negative feedback loop. So negative feedback loop is you take steroids, right? Testicle shrink, right? The feedback is more of the steroids cause the testosterone in the internal production to go down. Now taking that analogy to the stomach, as gastrin – as hydrochloric acid goes up artificially, gastrin levels don’t drop. You don’t have this atrophy happening. So it’s good to take it if you wanna give your digestive system a break or you’re eating a bigger meal and you just wanna make sure you can break it down better so you don’t have indigestion afterwards. Totally fine. Uh – ideally, you shouldn’t need it all the time. And number three is you can artificially or just uh – naturally stimulate it with the bitters, gentian, the chamomile, the ginger, etc.

Evan Brand: Well I kinda use the three S, too. Soup, salad, or smoothie. If you’re doing any of those three, you could probably opt out of the enzymes and be okay.

Dr. Justin Marchegiani: 100%. Unless you have a lot of digestive symptoms, that’s the key thing.

Evan Brand: Yeah. See, there’s another question here. Dale asked, “Can we share a quick functional medicine perspective on vaccinations?” That – we’d have to save that for another show, Dale.

Dr. Justin Marchegiani: I went into this with Dr. Robert Rakowski last week. So I would say, Dale, check out that podcast coming up very soon. We go into that a little bit.

Evan Brand: Here’s Betty. She’s got a question, too. What’s the logic behind any acids and PPIs? Profits don’t count as logic. Ahh. Okay.

Dr. Justin Marchegiani: So I talked about this a lot. So PPI is like if you’re – if you’re trying to create the perfect drug that works but creates so many other issues that will create more pharmaceutical dependency down the road, it’s the perfect drug. Let me walk you through it.  So you have acid issues because you’re not digesting your food, right? You have you know, the esophageal sphincter ‘s open, the food is not digesting. It’s rotting in your gut, the acids are rising up and hitting the top part of your throat. You start having symptoms. The first thing you may reach for is the over-the-counter Tums, right? Calcium carbonate lowers the acidity, it works. You feel better. Eventually you need to reach for a Nexium or Omeprozole or some kinda Prilosec, a proton pump inhibitor that prevents the hydrogen binding to the chloride molecules that makes the hydrochloric acid. So then you start having less as acid reflux symptoms. It works. You feel better. Now the problem is the more you shut down those proton pumps,  the less stomach acid, typically the less enzymes – one of things that starts happening is you become dependent on it because the gut lining becomes so irritated, inflamed. You’re not digesting your foods. So then what happens is you don’t break down the neurotransmitters, you don’t break down the fat and the protein that become the neurotransmitters and the hormones. So you start having mood issues. So now your chance of antidepressants go up, your – your chance of having more anxiety – because you don’t have the L theanine and a lot of the GABA coming in. So your chance benzodiazepines goes up. You’re not breaking down the cholesterol, so your chance of needing Viagra goes up because you have erectile dysfunction coz you can’t make your sex hormones. Uhm – you become more inflamed, typically. So then your chance of needing a cholesterol medication goes up because inflammation will increase your cholesterol. And the more you can’t break down certain minerals like magnesium, your chance of Lisinopril Hydrochlorothiazide, ACE inhibitors, blood pressure medications goes up. So you can see what happens. You’re on this medication and all these other medications are needed to help manage all the symptoms that come from it. It’s crazy.

Evan Brand: Yeah. I was gonna mention some of the research, too. I mean there’s research that links PPIs to kidney disease, dementia, heart attacks, bacterial overgrowth, infections, bone fractures, and also the fastest growing type of esophageal cancer. So there is a lot safer ways of dealing with heartburn than the PPI.

Dr. Justin Marchegiani: Yeah.  And HCL and enzymes are totally safe if you’re pregnant, too. I’ve had no problems with that uhm – with my pregnant patients – not an issue.

Evan Brand: Should we go to other questions?

Dr. Justin Marchegiani: Yeah.

Evan Brand: Or was there other stuff you wanted to mention first?

Dr. Justin Marchegiani: I think there’s one other element about enzymes – that’s taking specific enzymes on an empty stomach away from food can be excellent for cellular detox, cleaning up scar tissue, and even treating cancer. Dr Nicholas Gonzales, before he passed, was doing that successfully for many years. And you know, taking high-dose enzymes on an empty stomach, for me, that’s a first-line therapy for anyone with cancer. Those enzymes get into the bloodstream and they’re gonna be able to digest any bad cancer cells that weren’t tagged by the immune system for apoptosis.

Evan Brand: And can you mention briefly just the types of enzymes? Coz I think people may think enzymes are just one thing, but we’ve got digestive enzymes we’ve got proteolytic enzymes, we’ve got systemic enzymes which you were teaching me about last night. Uh – uh – talk – talk people through just the different categories. Just that way, we know  what we’re covering here.

Dr. Justin Marchegiani: Yeah. You’re gonna have enzymes like amylase and such which are gonna be more your carbohydrate enzymes, okay? You’re gonna have various proteases that help digest protein and those will have different names like trypsin or chymotrypsin, right? Protease, etc, etc. And then you’ll have various enzymes, lipases. And these will be more for digesting and breaking down fat. And also, you’ll have bile salts that kinda work synergistically with that. So those are your major categories. Carbohydrate, protein and fat. And like you said, the biggest people that tend to move away from me are ones that have low hydrochloric acid and enzymes, so they move away towards vegetables which actually have more natural occurring enzyme. So they – people that go vegetarian, right? They’re thinking, “Oh, you know, I just feel better on vegetables and not so much on meat.” If the meat’s inherently bad, it’s like, “No, the meat is exposing a weak link in your digestive track.” That’s what’s happening.

Evan Brand: Yup. Yeah. I wanna give a brief anecdote about my use of proteolytic enzyme specifically bromelain. After I got my wisdom teeth surgery, I was taking tons of bromelain and my gums healed in rapid time and the surgeon on the one-week follow-up was like, “Evan, I never seen anybody heal this quickly. What have you been doing?” And I say, “Well, I’ve been popping arnica like it’s candy and also doing tons of proteolytic enzymes.” And he was like, “Wow, this is – this is cool!” So, it worked.

Dr. Justin Marchegiani: I love it. And when you do these kind of enzymes for systemic use,  you want – there’s a couple out there. They’re a lot more expensive coz you’re using more serrapeptidase enzymes which come from the silkworm. Silkworm if you will look at kinda look at the thread that comes from their spinning or however – whatever they produce from a byproduct. The thread that they make their nest with and such is incredibly strong. The tensile strength is unreal. So they are actually extracting the enzymes the silk worms make uhm – make their net out of and they’re using in systemic enzyme formulas. And they put these enzymes in terracotta capsules coz you don’t want to use digestive enzymes for systemic enzyme purposes coz they won’t outlast the stomach. They won’t get to the stomach intact.  So you want something that’s enterically coated that gets into the small intestine, and then gets into the bloodstream without breaking down food. You don’t want any food to be there. You want it to be in a full empty stomach. And we use high-dose arm serrapeptidase enzymes enterically coated. And again, they’re gonna be a lot more expensive than your typical digestive enzymes.

Evan Brand: And when are those cases? I mean what – what’s like top few situations where S__  would wanna be on that?

Dr. Justin Marchegiani: Oh, yes. So we’re gonna do that with any type of cardiovascular issues – issues with uh –history of blockages, cardiovascular-wise. Uh women are trying to dissolve endometriosis and fibroids that can be helpful. Uhm – people that have cancer issues that are trying to just knock down some cancer cells. And then also just for uhm – scar tissue in the joints or just  the general cellular cleanse that help cleanse out debris in the body. But again, none of these treat or diagnose, right? These are all therapeutic things to help support whatever health issues that are already there. We just have to say that as our disclaimer.

Evan Brand: Agreed. Yeah. So I wanna just mention briefly about infections. So once someone’s got an infection, regardless of how they acquired, whether it was chicken or the egg which happened first, once you’ve got parasites, you’ve got this SIBO situations, etc, you’re set up for lower and lower enzymes and lower and lower HCL. So it really is uh – a long process that we take people through where you’ve got to remove infections, you’ve got to restore the gut, you’ve got to restore the enzymes, you’ve got to heal up the gut lining that are totally damaged. It’s a long process. Uh – Samuel asked – oh no, it was Cory here. He asked what would be the best HCL supplement for somebody with SIBO. And should you take both HCL and enzymes at the same time? You wanna hit on that one?

Dr. Justin Marchegiani: Yeah. Take HCL and enzymes at the same time? Absolutely. Because –

Evan Brand: You have to –

Dr. Justin Marchegiani: I mean enzymes – the only time I give them by themselves if someone’s gut is really raw and they can’t handle it. But again hydrochloric acid will help your body make its own enzymes by activating via pH – via low pH.

Evan Brand: Well – And I wanted to mention too, you know, you and I both got professional enzyme formulas, but the dosing is pretty conservative for that reason.

Dr. Justin Marchegiani: Uhm.

Evan Brand: So you may only get 200 mg of HCL per one capsule of enzymes and that’s so low that unless you’re just terribly inflamed, you should be able to tolerate  such a low dose of HCL like that.

Dr. Justin Marchegiani: Yeah. In my line, I have two formulas with HCL. I might digest energy that has lower hydrochloric acid levels that are meant for people that are already  have pretty good digestion, but just need a little bit extra support. And then they’ll have some enzymes in there, too. And then I have my two that I break up for more – for people that have more digestive issues. We’re trying to get more of a therapeutic dose. And some can’t handle that much HCL but need a lot more enzymes. So we don’t want the fact that they are in the same capsule to limit how much we can give. So we can go lower HCL, more enzymes, or vice versa. And we’ll kinda throw in some HCL tolerance test 1-4, 1-5 capsules on the HC – HCL. Any warmness, we back off by 1. Enzymes will typically go up between 1 to 4. If we feel a lightening, or better digestion, or improved bloating, or gas, or any symptomatic relief, or just a feeling of better digestion, then we’ll keep it at that those. If not, a standard 1 to 2 capsules per meal is typically okay.

Evan Brand: Here’s another question. “My doctor put me on Ornidozole and Levofloxacin.” Oh, man. “I have hunger pains, fatigue, constipation, felt better for a week and then hit a wall. How effective are these? And side-effects?” So, those are two antibiotics and –

Dr. Justin Marchegiani: Well, anytime you take an antibiotic, one of the big side-effect is gonna be a rebound fungal overgrowth, alright? Lots of females have noticed they take antibiotic, they get a reoccurring yeast infection weeks later. And a lot of conventional physicians are actually growing wiser that their patients – their female patients a lot of time, like a Diflucan  or Fluconazole after antibiotic. Now again, you’re much better off giving them a probiotic. You can do it even during just away from the dose. And then do a probiotics after a month or two afterwards just to prevent that rebound overgrowth. And a rebound overgrowth is let’s say you have a lot of good and bad bacteria in your gut, you give antibiotic, what happens is you lower all of it. Now, the good bacteria provides a nice environment so the bad stuff can’t grow. So as soon as the good stuff is low, then the bad stuff naturally proliferates. It’s the whole idea of once you clean out your garden, the tomatoes don’t just automatically, the weeds do. You actually have to go in there and plant the tomato seeds or whatever you’re growing. You have to plant those seeds, you have to aerate, you have to put the fertilizer down to create the environment so the vegetables grow.

Evan Brand: Good analogy.

Dr. Justin Marchegiani: You don’t have to do that with the weeds. The weeds are automatically there on auto dial, so to speak.

Evan Brand: That is such a good analogy. Yeah. And it’s amazing. How about unless it’s a life-threatening situation, try not to go with antibiotics, anyway. Figure what the root cause is. There’s so many natural antimicrobials that you and I use in they’re so effective. They have no side-effects, no lasting – anything. They’re in and out.

Dr. Justin Marchegiani: Absolutely.

Evan Brand: And then we don’t need stuff like Diflucan which is also terrible, which in many cases you’re gonna just basically piss of the candida. And yeah, you’re gonna get rid of it  but then the candida’s gonna come back with a vengeance. And we test your urine, we’re gonna see massive arabinose –

Dr. Justin Marchegiani: Yeah.

Evan Brand:  Or tartaric acid.

Dr. Justin Marchegiani: Yup, yup.

Evan Brand: Back with a vengeance you’ll say, “Oh, I just finish a round of Diflucan.” And it’s like, “Whoa! Maybe it worked for a day, but candida is back and she’s mad.”

Dr. Justin Marchegiani: Exactly. Alright. So let’s summarize everything we chatted about here, Evan So like, let’s say you’re just tuning in now or you just get really overwhelmed and your eyes got a little gloss over. What’s the Reader’s Digest version? I’ll let you go first.

Evan Brand: Yeah. So to me, reader’s digest version – enzymes and HCL are crucial. They are one of the most important foundations you should have if you want to be a healthy human that lives a long life, plain and simple. And then the caveats to that are well, do have things in your body that you need to work with a functional medicine practitioner and get tested for, such as infections like parasites and bacterial overgrowth like SIBO and candida. Now, if you get the testing piece done, you find out that your free of infections, which is pretty rare, then awesome. Maybe you’re just at a lower dose of HCL and enzymes, and maybe if you do soup, salad and smoothies, you don’t use enzymes but otherwise, you’re kinda cycling on. And you’ve got a cute little glass jar like I do that I shove in my wife’s purse. It’s got may enzymes and HCL in there. I take it if we go to restaurants and I always have it on the dinner table because if its out of sight, it’s out of mind.

Dr. Justin Marchegiani: Totally.

Evan Brand: So when I sit down at the dinner table, the enzymes are right there. Uhm – as you get older, we know with the works of uh – Steven Wright. HCL is gonna drop, so to me, it’s not an optional supplement if you want to be healthy. Mother nature just doesn’t care about your optimal digestion once you’re 40, or 50, or 60 because you’re pass the hunter gatherer reproductive age which was like 16 to 20 years old. So mother nature doesn’t want to kill you but she just doesn’t care if you digest your grass-fed beef when your age 40 to 50. So enzymes become a must. You wanna mimic the stomach acid levels of when you were younger and you had an “iron stomach” You wanna try to macht that with supplements.

Dr. Justin Marchegiani: Absolutely. And then in the future, what I’m gonna do is, anyone on Facebook, I’m gonna put the link in for the live YouTube side just so we can have people that uhm – want to see the full thing, they can go to YouTube and check out the whole thing. I wish we could make a go live on both sides here but right now the technology doesn’t quite do that. So we’ll shoot over the YouTube link in the future and just to add one last thing. Get the parasympathetic nervous system response going. Make sure you’re in a stress free, kinda relaxed environment; make sure you’re chewing your food enough times, uhm – get the saliva going to help start the digestion in the mouth. Then last but not the least, if you are really gluten sensitive, and you may be getting exposed somewhere like you’re going out to eat, and there maybe some contamination that you’re unaware of, enzymes that have dipeptyl peptidase for DPP4 enzymes can be helpful because that will help break down any bits of gluten. And the more the gluten can be broken down into smaller constituents, the better the body has a chance of dealing with it better. So keep that as a little side note, DPP4 enzymes can be hepful.

Evan Brand: What – When is the right and wrong time to use those?

Dr. Justin Marchegiani: Well, the wrong time is I’m gonna have a birthday cake, but it’s okay because I’m taking my DPP4 enzymes. It’s not necessarily for that, but if you are gonna have it though, it will lessen out the blow. But we don’t wanna give someone a crutch to be able to make a whole bunch of bad decisions. But if, let’s say I’m ordering some food at the restaurant and maybe there’s something in there, having it be handled by someone that just have their gloves on that handles someone’s breaded item. So you will do it more for incidental exposure just to prevent that so your body can deal with the gluten of – from that perspective.

Evan Brand: Love it. That’s great advice. So that should in your suitcase then if you’re travelling. We should do an episode on that. I think we did a travel hack episode.

Dr. Justin Marchegiani: We did.

Evan Brand: We should do a – on the go. Like if you’re not travelling but you’re just going out and about in the city and you may stop somewhere to get some food. What should you have, just in case.

Dr. Justin Marchegiani: Totally. That makes sense.

Evan Brand: So much fun.

Dr. Justin Marchegiani: And I’m gonna do maybe another Q&A. If I have time, I’ll make you another quick Q&A taken today. We have a couple of people here that are asking questions. They’re a little bit off-topic which is fine. But we’re only gonna answer the ones that are more on-topic. And I’ll try to have more Q&A conversations wherein we can take of everyone else’s questions.

Evan Brand: Also, last thing. If you have it, you should sign up for SpeakPipe. That way, people can send us audio questions and then we can play the audio clips and put them in for our podcasts.

Dr. Justin Marchegiani: Love it. Great idea, man. Any last thoughts, Evan?

Evan Brand: No. If people need help, reach out. justinhealth.com   notjustpaleo.com We’re available and this is the stuff we work on everyday.

Dr. Justin Marchegiani: Love it, man. Well you have a- awesome Friday, man and we’ll talk really soon.

Evan Brand: Take Care. Bye.

Dr. Justin Marchegiani: Bye.




Healthy Meal Tips – How to Create a Healthy Meal

Healthy Meal Tips

By Dr. Justin Marchegiani

Keeping in mind that what we eat should be nutrient-dense, toxin-free and high-quality is what this video is about. Gain beneficial information regarding the three macronutrients which are proteins, fats and carbohydrates. Know more about the different types of carbohydrates that we need depending on our activity level. Learn how to set up your own quality, nutrient-dense and toxin-free meal with the variety of foods discussed here.



Every single meal should have a combination of three macronutrients –  proteins, fats and carbohydrates. We are just taking  fully into account that quality is really important.  A lot of people just talk about macronutrients like proteins, fats and carbs and do not emphasize the quality of nutrients that are very important. So, obviously organic, chemical-free pesticide-free, free-range, GMO-free. All these things are really important present in macronutrients.

The big thing is I’m going to emphasize macronutrients that also don’t have a lot of toxins in them. A lot of toxins are just phytates, oxalates, various fibrin compounds. Things that trip an inhibitor. Our enzyme-blocking inhibitor compounds can also affect digestion and your ability to breakdown and utilize B proteins and nutrients for food. And next is we also want to make sure that food are anti-inflammatory.

Three Prostaglandin / Eicosanoid Pathway

  1. Prostaglandin 1 (anti-inflammatory)
  2. Prostaglandin 2/ Arachidonic Acid (pro-inflammatory)
  3. Prostaglandin 3 (anti-inflammatory)

I’m going to be talking about various proteins and fats that are going to stimulate the anti-inflammatory 1 and 3 pathways vs. the refined vegetable oils, GMO vegetable oils to stimulate the prostaglandin 2 pathway.


Proteins and Fats

We’re going to have protein, fats typically come together when you eat at lunch or eating protein powders or once you’re eating rabbit protein. They have rabbit starvation up in the  in the wintery areas because the rabbits are so lean. They develop rabbit starvation of this protein hydro excess with no fats, and you actually need fatty acid to be able to help absorb proteins and amino acids so you can develop rabbit starvation without enough fat. But typically, in mother nature, you’re going to have protein, fat together. I’m a big fan of at least making half your meal, put half your plate with protein and fat.

If you are very active or if you’re a wall closer to the equator, you may be able to use more carbohydrate for fuel. So you actually see yourself in 3 quarters to 16% carbohydrates. But if you’re relatively leaner, you’re not exercising too much, and you’re living a pretty good lifestyle, typically about half protein, half fat. And that can change based on your activity levels, your kinetics, whether you have an autoimmune condition or not.



We have a couple of different kinds of carbohydrates. We actually have starchy carbohydrates. This would come in the form of white potatoes, sweet potatoes, yams, tubers, bananas, etc. We also have non-starchy carbohydrate.

I’m a big fan of non-starchy varieties because it tend to be higher in nutrition. But they don’t have all the sugar that you may get with the starchy carbohydrate. This tend to be a really good place to get all the nutrients, all these anti-cancer compounds in the non-starchy variety.

Now again, if you’re more active, you may need some of the starchy carbohydrates. So this is kind of dependent upon your activity level, as well as your genetic predispositions and also you know, assuming that you are healthy. If you’re diabetic, you have metabolic syndrome, if your waist is greater than 40 inches for male or greater than 35 inches for female, you may want to think about really keeping those starchy carbohydrates down, if not out of your diet completely.

High Glycemic

This can be pineapple, this can be banana, papayas, dates, mangoes, maybe more of your tropical fruits. Now people- but, of all the more tropical environment, they may have the genetic ethnic and biochemical individuality to process those carbohydrates at a higher level. Now if you got more wintery environment, you haven’t had those type of fruits. So you maybe a little bit more sensitive to it, you may not be able to eat as much.

Low Glycemic

Low glycemic may be your berries, maybe your apples, like your green apple. Things like that, usually below above 40 glycemic index are going to be your berries or apples, maybe more of your Granny’s Smith apples and such. It kind of gives you a good idea of what your low glycemic fruit maybe.

So myself, I typically try to consume more non-starchy and more low glycemic fruit. If I’m more active, then I will do a little bit more starch, at least more of these sweet potatoes. And again, out of the starchy ones, the sweet potatoes are actually lower on glycemic index than your white potatoes.

So just kind of keep that in mind. And typically all of my carbohydrates are still gluten-free. So I typically try to consume gluten-free carbohydrates just because we’re trying to keep up with the fact that our goal’s anti-inflammatory, nutrient dense, low in toxins, and gluten-free. These are all gluten-free here.

Know more about gluten-free carbohydrates by CLICKING HERE


Healthy Meal

So proteins, fats, carbohydrates- from there, you can create your meal.


If you’re looking at proteins, it could be fish, it could be turkey, it could be grass-fed meat, it could be lamb, a good quality steak or beef. When we look at our fats, typically protein and fats are connected. So we’re looking at beef, and maybe a 76% grass-fed beef and maybe a dark turkey leg or chicken thigh, or the chicken breast- we’ll leave the skin on. If it is a leaner meat like a chicken breast, maybe we put a scoop of coconut oil in there; or we cut out the half to a whole avocado and put it on there. We can also have a handful of nuts or almond to get that extra fat. And again, we can obviously cook with fat, too.


Good healthy fats, maybe coconut oil or ghee. If you’re autoimmune, you may want to avoid the grass-fed butter or use something like ghee without the P casein protein in there. Also nuts, it could be good quality bacon fat and duck towel,  macadamia nut oil, avocado oil which are pretty good fats. It could be olive oil. Using olive oil as the salad dressing. That kind of gives you an idea of proteins and fats.


Our starchy carbs are going to be our sweet potato, our yams, berries, tubers,  squashes, white potato.

Non-starchy ones are going to be our spinach, its’ going to be our salad mix, our broccoli, our kale, our asparagus, our cauliflower, and spinach, etc.

Our high glycemic fruits of foods are going to be obviously, our white potatoes are going to be our high glycemic index. Obviously, sugar in general. We are keeping this list gluten-free here, just in case.

Low glycemic are going to be our berries, our passion fruit and our Granny’s Smith apples, our grapefruit, as well as our lemons and limes.

So I hope this video is really helpful. From here, you should be able to create an anti-inflammatory, nutrient-dense, low toxin meal. Start pushing your body into anti-inflammatory state, which is essentially your body building up faster than you’re breaking down.

So if you’ve hormonal issue, or digestive problem, if you’re in chronic pain, if you have fatigue, or depression or a mood issue, this is going to be the kind of diet template-wise, maybe a couple of tweaks regarding macronutrients. This is the kind of diet you want to be on health, bring yourself back out well.

For more information about myself, feel free to visit the information bar below. If you need a consultation regarding what tweaks you can make to your diet or what lab test, feel free to reach out and I will be able to help you out.

CLICK HERE and ask an expert about tweaking your diet to fit your needs

The entire contents of this website are based upon the opinions of Dr. Justin Marchegiani unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Justin and his community. Dr. Justin encourages you to make your own health care decisions based upon your research and in partnership with a qualified healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Dr. Marchegiani’s products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products.