In this engaging discussion, Dr. J and Evan Brand delve into the intricate relationship between gut health and skin conditions, emphasizing how underlying gut dysfunction can manifest as various skin issues, including acne, eczema, and general skin aging. They explore mold exposure's role in gut dysbiosis, which can lead to systemic health problems and negatively impact skin appearance. Through clinical experiences, they reveal how environmental factors, dietary habits, and hormonal imbalances contribute to skin health and overall well-being. They advocate for a holistic approach, recommending dietary adjustments, improved air quality, and natural topical treatments to promote healthier skin. The conversation also touches on the importance of collagen and healthy fats in maintaining skin integrity while cautioning against relying solely on pharmaceutical solutions like Accutane without addressing the root causes of skin issues.
🌱 Gut-Skin Connection: The gut's health is directly linked to skin conditions; addressing gut dysbiosis can lead to improved skin health.
🦠 Impact of Mold: Mold exposure can create significant gut dysbiosis, leading to various health issues, including skin problems.
🥑 Role of Nutrition: Consuming healthy fats and collagen-rich foods is essential for skin integrity and moisture.
💧 Importance of Moisture: Keeping the skin hydrated is crucial for its health and appearance; the right moisturizers can make a significant difference.
🧪 Holistic Approach: A comprehensive strategy involving diet, environmental factors, and lifestyle changes is necessary for effective skin care.
🚫 Risks of Pharmaceuticals: Medications like Accutane may temporarily relieve skin issues but do not address underlying causes.
🧬 Hormonal Influence: Hormonal changes can significantly affect skin elasticity and health, particularly in women.
Dr. Justin Marchegiani: Hey guys, it's Dr. Justin Marchegiani. Welcome to the Beyond Wellness Radio podcast. Feel free and head over to justinhealth. com. We have all of our podcast transcriptions there, as well as video series on different health topics ranging from thyroid to hormones, ketogenic diets, and gluten. While you're there, you can also schedule a consult with myself, Dr.
J, and or our colleagues and staff to help dive into any pressing health issues you really want to get to the root cause on. Again, if you enjoy the podcast, feel free and share the information with friends or family. And enjoy the show. And we are live. It's Dr. J in the house with Evan Brand. Today we're going to be talking about skin.
We talked about acne before. We're going to be talking about just improving your skin health through gut function. We're going to connect guts and ideally a little bit of the hormones to healthy skin Function, complexion, health, anti aging, wrinkles, the whole nine yard, what you can do to kind of really stay healthy in that area.
Evan, my man, how we doing today?
Evan Brand: Evan Brand Hey, I'm doing really good. I'm out of the house. I'm uh, out of my front patio. Beautiful morning today. Sky's blue. The trees, the pine trees out here look awesome. Majestic in the morning sunlight, and I just fog my house. I like to do the fog about once or twice a year, and I'll jump straight into mold real quick.
Uh, the, the mold skin connection, because you and I, clinically, we're seeing a lot of people in their 30s, their 40s, their 50s that have skin issues, acne, and other skin problems, and you would think, wow, shouldn't they outgrow that? They're 30, 40, 50 years old. How do they not outgrow their, their skin condition?
And the reality is this. So it's in the literature. It's published that mycotoxins create dysbiosis in the gut. Someone could come to us and they're eating paleo, they're eating AIP, they're eating animal based, they're eating real food, but yet their gut is still a mess on paper. In fact, I had a female yesterday.
Her diet was absolutely perfect, but her gut dysbiosis was through the roof. And she had been living in mold. She had nowhere to go. It was her grandparents house that she got gifted. They didn't take good care of the place and she had major dysbiosis. So if you live in a moldy building work, any moldy building, you go to school, any moldy building, your children go to school and a moldy building, which that was a case I saw yesterday as well.
two kids that are twins. They both go to the same school. It has water damage. The mom can smell it. The school won't do anything to remediate it. That's creating dysbiosis and that dysbiosis is then going to create skin issues, nutrient absorption problems, mental health issues, behavior, anxiety, depression, irritability, anger, rage, insomnia.
So, this thing could really be a, a catastrophic domino effect. Dr. Justin Marchegiani
Dr. Justin Marchegiani: And I had a patient here in the last few months in down in Florida. who was renting a house or room in a house, and they had mold behind their shower. And we did plate testing. We saw lots of aspergillus and penicillium come back.
And I was like, we got to remediate the tenant. The landlord was not interested in doing that at all. So they were stuck. They had a really good deal on their on the rent. I said, Hey, let's do this. You're in Florida. Like, what's your humidity in the house? It's like, Oh, 55%. Hadn't get a meter. Like, all right, well, let's at least get it down into the mid forties.
So we got a dehumidifier. We got it in the mid forties. We got a, um, really good air filter. We got an Austin or an air doctor, one of the two. And we just did that for a month. We kept the humidity down. We got the air doctor going or we got the Austin air going. I had at least put a, a fan during the day on that part of the drywall that was getting soap because it was a leak behind the, behind the shower.
And it was hitting that wall. And so we at least got that down. We retested a month later and we had all the mold spores down negative. So we didn't even touch the drywall. So obviously there's still mold behind there, but we at least knocked it down to the point where it's not going systemic. And so that's a huge change when someone has systemic issues and you lower it so it's not even detectable.
That's great. And that's why. People may have some mold issues in some areas of your home. The bigger question is, we don't want to stress people out saying, well, you should be knocking everything down and looking behind. That's stressful. That's costly. But if we can just get the air quality better through lower humidity, because humidity is the fertilizer that allows mold to grow, it allows allergens to grow.
And if we can get the air filtered out, three things for mold to grow oxygen, which is a given for most people. Um, we have carbohydrate, which is dust at a micro level. At a macro level, it can be drywall or wood or, or flooring. And then we need carbohydrate and carbohydrate can be the drywall, the wood, but it also can be the, um, the dust.
And so we can lower all that. So we, we have oxygen, we have water and water can be humidity or it can be in a leak. And then we need carbohydrate, which could be dust or it could be building material. So we can at least do our best to get the carbohydrate dust down and get the humidity down and that can make a huge difference.
Thanks. Dr.
Evan Brand: Justin Marchegiani Yeah. And uh, Kerry asked, uh, how do you fog specifically? I've got a video on my site or if you just reach out on my contact form, evanbrand. com. I've got a video that we can send you. It's a free kind of a free demo that shows you how to do that. And so yeah, it's an important step.
And I find that many people are, like I said, they're eating perfect when they come to us and they still have gut dysbiosis and therefore they have skin issues. Now I was trying to dig up a picture. I don't have anything on this computer here, but I'd say 15 years ago, When my wife and I first got together, my skin was so bad and I was into bodybuilding and I was putting on muscle.
I was getting strong, but I was eating every two to three hours and I was not eating the best. I mean, I was doing non organic oatmeal 15 years ago. It was fine. It was hard to find organic oatmeal 15 years ago. There might be like one store in town that would have it, but I was trying to bulk up. I was doing, um, Lots of dairy.
I was doing milk because a lot of bodybuilders are pushing milk, like go mad diet, gallon of milk a day. And so I was doing, I was doing a lot of these things from, from the diet perspective to, to try and bulk up. And that was definitely hard on my gut as well. So I will say that maybe you've, you've rolled out mold.
I would, the next thing I would look at would be dairy, especially for children as well. I think my kids, I think they're pretty sensitive to dairy. I just don't think that young kids really have the, the developmental firepower in their gut to handle dairy. What about your kids? Do you think they have issues with skin after dairy?
Do you think it's triggering for them or?
Dr. Justin Marchegiani: And I put dairy in like in a couple camps, right? You have dairy like raw milk, organic. We get raw milks that have enzymes in there. It's not that the fats aren't going to be damaged through the homogenization and pasteurization process, but you still have to process it.
I still get massive diarrhea with even good raw dairy. So we have dairy from milk. Cheese tends to be better because if it's fermented, the fermentation will decrease the lactose in there, so you'll have less lactose. Many people have, they'll have, they'll be lactose intolerant where they can't break down the sugar that can create diarrhea or bloating or gas.
Then they may be casein intolerant. Casein is the protein that most people are hypoallergenic to. And then we have, of course, um, after that is the butter fat. And then we have different versions of it. Butter is butter fat. And then we have ghee, which is clarified butter, where they heat it up and they skim off any of the extra casein and lactose on the very top of the butter.
And so, worst case, you start with ghee. So we do most of our cooking with ghee. And then maybe a little bit of butter on some vegetables with some sea salt is a great way to get some high quality dairy butter fat without the casein and the lactose, plus you have some really good fat soluble vitamins which are really good for your kids brains and it's really good for your skin, right?
This outer part of the skin is all a lipid bilayer that requires healthy, uh, lipids. fats to have integrity and have good moisture. Evan
Evan Brand: Brand Yeah. And I've seen vegetarians, vegans with poor skin quality. There's not as much of a supple nature to it. The skin definitely looks more parched is probably the best way to put it to you.
Their skin's just more dry. Dr.
Dr. Justin Marchegiani: Justin Marchegiani Women are at risk because women, people don't realize this. Women have 50 percent less collagen in their skin than guys do. It's why if you take a, a 40 year old man to a 40 year old, um, female, you may notice like more crow's feet or more elasticity. You know, we're talking like no makeup, no Botox, right?
It's because I think it's a hunter gatherer thing, right? It makes sense that skin was essentially our outer barrier against predators. So, there's been just an adaptation over, over millennia where men actually have about 30 to 50 percent more collagen than women do. And so, yeah, look that up. So, that's a real stat.
So, the first thing I tell all my female patients is we need to get collagen. We need healthy fats. in your skin. So, we have to be consuming healthy fats, pasture fed yolks, egg yolks, grass fed meat, and get collagen in your coffee or tea or do bone broth because you need the building blocks to help your skin.
And just doing a whole bunch of chemical peels and laser stuff, um, I mean, there may be some gentle ways to add, use red light to increase collagen or to use microneedling as a stimulatory mechanism. But if you don't have the building blocks, behind the stimulation, you're not going to improve the collagen.
That's where a good red light laser or a good, um, you know, um, microneedling device can be very helpful as long as we have the collagen, the nutrients, the B vitamins like the biotin and the good healthy fats to bring the integrity up. Also too. Like I've really worked on my skin complexion for a while, but in high school, 25 plus years ago, I had rosacea.
Really, really bad rosacea. Full on red. And so I worked on that because there was an autoimmune component with gluten and dairy and processed foods. And then also to um, just, just having a lot of dry skin too. I didn't, I didn't use the right type of skincare routine to hydrate my skin. Any plastic surgeon will tell you one of the best anti aging things is keep your skin moist.
The question is what do you keep it moist with? Is it paraben laden? Junky moisturizer are using good, healthy fats to build up that healthy lipid bi layer on your skin. So we wanna not provoke it with autoimmune foods and which then drive gut permeability and autoimmunity. Again, I have Hashimoto's, which I'm able to keep in check.
And then do we have good gut function to absorb all of the nutrients to help build up that lipid vi layer?
Evan Brand: Let me share my screen here. If you can pull this up for us. Um, I want to, I gotta enable a privacy setting real quick and then we should be able to rock. But I want to show people. Just how young this can affect people and this is a case of an 11 month old.
Can you see my screen? Okay, so try to make a little bigger for people watching here And if you're listening on the audio, you can check out this video. It's on the Justin Health YouTube channel You can view the video, but this is just a little slide that we made here. This is an 11 month old I saw her last week.
So 11 months old food sensitivities eczema And she had severe colic and I just want to show people what this looks like on paper because when you see a young child and you take them to a pediatrician, look here, patient age zero. Okay, so not even a year old yet. And what's crazy is the mom. She had actually much more toxicity.
Or I'm sorry, the baby had much more toxicity than the mom. So if you look at nutrient levels, we'll often see things like this, like B6 is gonna be low, we'll see vitamin C low, which you need a lot of vitamin C for collagen. You were talking about collagen, how important that is. Vitamin C is a cofactor there, so that's important.
Also, biotin was low. Dr. Justin Marchegiani Oh,
Dr. Justin Marchegiani: just real quick, do you always see people with low vitamin C. I almost always see him with low vitamin C on the out.
Evan Brand: Yeah, and I had somebody comment the other day and they said, duh, it's supposed to, the half life is so short, but I don't think so because I see people that are supplementing adequately and their levels are actually okay, but the people that are not supplementing, yeah, they're low.
All the time and also people have mold as well. So I typically blame it on toxicity issues, maybe heavy metals, pesticide mold. Cause if you look here at her ochre toxin, she's off the charts. I mean, she's a one Oh four, anything above seven and a half is bad. She's a one Oh four. So that's what I usually blame.
Um, but I want to show just like I said, how young this can strike people. So if your child has skin issues, if you go to the dermatology, you go to the pediatrician, they're likely going to do a steroid or some sort of a topical treatment, but we're not going to have to do that for this girl. If we simply fix this major toxicity issue, she's going to be totally fine.
Now, if we look at her GI map, let's check that out as well. She already showed up with a pretty bad clostridia problem. You can see here on page one, not good for 11 months old. Look at that H pylori. Already high. Not even a year old yet. Mm. Keystone bacteria stuff's a little wacky here. There's no akkermansia.
And then look here at the dysbiosis. Oh,
Dr. Justin Marchegiani: holy smokes. Yeah. Lots of stress. Yeah. You're talking a thousand x elevation in some of these. That pseudomonas is a thousand x elevated. Yeah, that's really high.
Evan Brand: I don't like these down here either. Evan Brand How did the
Dr. Justin Marchegiani: fungus and yeast look?
Evan Brand: Dr. Justin
Dr. Justin Marchegiani: Marchegiani Everything was pretty clear on that.
Evan Brand And I tell patients, um, it's really hard for the GI map to pick up a lot of the fungus and yeast. Dr. Justin Marchegiani Yeah. Evan Brand We find the, the D arabinose or the yeast markers on the oat much more accurate for yeast overgrowth. Dr. Justin Marchegiani
Evan Brand: Look at this though. Yeah.
Absolutely. And look at this. Um, so you and I are running more of these labs than almost anybody worldwide. And so we've seen the changes in these labs over the years. And one of the relatively new markers they've added here is this Acinophil activation protein. Now when you look at the literature on this, this is much more elevated in people that have irritable bowel syndrome or irritable bowel diseases.
So unfortunately, this kid, basically a one year old, already has IBS. There's major food sensitivities. There's major skin issues already. And so, there you go. Look at that Acinifil activation protein being elevated. Look at the secretory IgA. Now, you see calprotectins creeping up here into the yellow.
She's at a 113. So, this poor kid already has gut inflammation, already has gut damage, massive dysbiosis. And so, I want you guys to understand this is what real health looks like. This is what real skin care and skin improvement looks like. If you're simply just going to your Botox lady and you're getting a hundred units of this and that, and I mean, yeah, maybe you could, you could kind of fake the look, and you could plump yourself up with that, but internally, you could still have all this going on, which is gonna increase your risk of chronic diseases.
She doesn't have any glucuronidation issues, but if she did, I mean, that increases cancer risk and all sorts of things.
Dr. Justin Marchegiani: Dr. Justin Marchegiani Yeah. Also, too, can you put that back up, Evan? Evan Brand
Evan Brand: Yeah. Dr. Justin Marchegiani
Dr. Justin Marchegiani: People talk about like histamine and inflammation, so let's go back to that EPX protein.
That's an eosinophilic activation protein. Now, the eosinophils History can activate the eosinophils. So when I see people talk about histamine, that can be a really good marker to potentially look at histamine. The problem is many people are overly focused when they talk about mast cell disorders. The problem is, where is the mast cell dysfunction coming from?
So people will talk about food or mold. Yes, those are big things, but people forget if you go look at the gut section here, pull this back up, the eosinophilics is really high, and then also calprotectin. Anything greater than 50 is considered in the yellow. That's made by the neutrophils. So the neutrophils make this calprotectin in regards to inflammation, and then the eosinophils make this protein.
So, that can easily be driving histamine. Or I should say histamine can easily be driving this immune activation. And then bacteria can easily be driving calprotectin because it's the neutrophils that are responding. And the neutrophils go after bacteria. Now look at all this here. These type of bacteria could all be producing histamine.
A lot of histamine can come from the guts. And again, guess what histamine does, right? Histamine easily creates redness and fleshing in the face. That's why. I mean, you see it, you know, for instance, in, in the Asian population where they'll have the Asian glow with um, alcohol and they'll take like a Pepsodacy or an H1 or H2 blocker to decrease the redness.
So you could just connect to get back to gut, right? Or skin. You can easily have all this histamine low from the bacteria that creates that flushing of that skin and that excess redness. And also gluten can cause that too. Gluten can easily feed the bacteria. And then, of course, if you're getting exposure to Roundup or glyphosate, which is a pesticide, originally patented as an antibiotic that could be easily wiping out some of the beneficial bacteria creating rebound overgrowth because of the glyphosate exposure as well.
Evan Brand: Evan Brand
Dr. Justin Marchegiani: Yeah.
Evan Brand: And this can happen at young ages. So please don't think, hey, uh, uh, my kid is one, my kid is two, my kid is 12, my kid is 15. We're just going to go do Accutane. We're going to go do steroids. Like, sure. So, Uh, that, that video that, that you and I recorded, uh, we went out to Del Mar, San Diego area this summer.
Evan Brand We had a fun time. We recorded a video with Brendan of Santa Cruz Medicinals. Dr. Justin Marchegiani we covered a lot of skin health and one of the, the videos that we recorded together, he, he titled it something like Accutane the Ugly Truth. And I looked back at the comments on that video and a lot of people were very just pro accutane.
They're like, just do it, just do it, just do it. Don't worry about these guys, you know. And so they were basically just saying, go ahead and, and do this. I've seen long term impacts on people, and people that regret taking it, and once again, it's not root cause. You can take Accutane, you can fix your skin possibly, but you still have these underlying root causes which are driving your sleep and your mood issues.
So, I don't think it's worth it to just skip over this stuff. Dr.
Dr. Justin Marchegiani: Justin Marchegiani Also, just step back, look at the mechanism, right? Look at the physiology imbalance that's causing that to occur. So, okay, what does Accutane do? It's a synthetic vitamin A analog, right? All right. So, vitamin A does a thing in the skin.
What does vitamin A do? Vitamin A can decrease oil production in the skin. Okay, great. So, we know Accutane is a synthetic vitamin A. We know there's all kinds of black box warnings for suicide and depression. And we know also too much of it can create systemic dryness in the eyes and the skin. even permanently.
What's the mechanism? It's decreasing the oil production, the sebum, which then feeds the cutie bacterium, acne bacteria in the skin, which then creates the cyst and the inflammation of the comedones. All right, so how can we get vitamin A therapeutically to decrease oil production naturally? We can do higher dose cod liver oil.
We can do higher dose liver glandular. We can even do a, a retinol, a vitamin A oral sublingual if we need. So there are natural ways we can bump up vitamin A to help. We can also use a high quality sulfur soap. 10 percent or higher to decrease the oil on the skin as well. Naturally, decrease the oil load, use a witch hazel based toner to lessen the oil, pH balance the skin.
And then also, why is that oil happening? We have to look at insulin resistance or reactive hypoglycemia can easily fluctuate and drive more oil production. So, there were some dermatologists back in the 1920s, they were using probiotics and cod liver oil to treat acne in the 1920s. They're called Pillsbury and Stokes.
You can Google it. Pillsbury, Stokes, Dermatologist, right? So we can use cod liver oil. We can use liver, vitamin A. We can do egg yolks. We can do topical things to help the skin. Again, topical salivation. It's 80 20. 80 percent of the skin issues are gonna be due to your food, your gut, your diet, your hormones.
But then topically, Right? We can do things to help as well. So I'm a big fan of 10 percent sulfur soap. I'm a big fan of witch hazel based toner. Very clean, no alcohol in it. I'm a big fan of moisturizing with high quality emu oil, right? Commonogenic to scale one through five. Commonogenic means it's, it's going to clog pores.
Emu oil is a one out of five. So it's very, very low. Will not clog pores. It's the number one oil they use in burn victim units in hospitals. When you have third degree burn. So, it's very anti inflammatory, very healing for the skin, supporting of that, that natural lipid bilayer and the microbiome on the skin.
So, I love good fats like that. So, we take a step back. What's the mechanism with Accutane? Vitamin A, oil reduction. What can we do naturally? We have all these other avenues that we can do that are more natural, less side effects. and actually still get to the root cause. Evan Brand
Evan Brand: Yeah, well said. And uh, we're gonna boost up vitamin D as in Delta as well.
So if you look at, just type in microbiome vitamin D, you can read the papers on this, but it's well known and established that if you have a vitamin D as in dog, vitamin D deficiency, that's gonna create more dysbiosis. And so by boosting your vitamin D levels up to a healthy level, let's say 60 to 90, NG over DL is what we use in the U.
S., that level is going to reduce your skin issues by improving. The diversity of your gut. So that's pretty wild to see. Um, when you and I look at organic acids testing, even if we don't have blood, we can infer vitamin D levels based on a few key markers like phosphoric acid on the oat test. But if we were to run blood, most people, especially now we're recording this late October here, people are getting into vitamin D winter to where if you're pretty much North of Atlanta.
You're not going to be making vitamin D for the next few months. Even if you're outside with your shirt off, there's going to be a very tiny window at certain points of the year where you cannot make vitamin D at all. So this idea that you'll just sit out on your patio for a day with your shirt off, it's just not going to work.
And we've seen people that even live in coastal areas, they're getting lots of sun, they still have D deficiency.
Dr. Justin Marchegiani: Absolutely. And there's also a certain virus that's been out there for a few years that can actually cause pathogenic bacteria to thrive. This is an NIH study here so you can read it on screen talking about certain viruses disrupt the gut microbiome, allowing pathogenic bacteria to thrive.
Uh, it can also act allow these gut bacteria to enter the bloodstream, leading to secondary infection. So we know how important the gut is with the skin, but we also know that certain viruses can negatively impact the microbiome. So, if certain people get maybe a certain virus here, we may wanna use probiotics for a month afterwards, just to be safe to prevent a rebound overgrowth.
Evan, your thoughts?
Evan Brand: Yeah. And I'm seeing a new variant. I think our family just got hit with it a few weeks ago. It was a pretty, pretty tough one. And it, it, man, it, it did a number to my gut. I'll, I'll, I'll tell you that much. And there was no issue with smell or taste this time around, but this thing is still floating around.
So I'm seeing it a lot. And I think a lot of people are being hit with it. So, yeah, I mean, I personally just stay on it. our probiotics. We have some good formulas that you and I manufacture. So I just stay on those because who knows what you're getting exposed to. And I don't want my diversity being knocked down.
I really, I want to work hard and be a good dad, be a good husband. I, I can't afford to be knocked down by something like this.
Dr. Justin Marchegiani: Dr. Justin Marchegiani of crazy, but you know, these are NIH funded studies actually showing some of these things. So it's amazing how far we come in the last couple of years on certain topics.
Um, but in general, gut microbiome, big deal, right? So, we talk about topical things, red light, infrared light, um, a microneedling, great. I have a lot of videos on this topic of microneedling. Um, I'll try to put a link down below or maybe a pinned comment of all the different products I use. I'd rather not make this an infomercial.
There are things out there. I only recommend things that I actually do myself or with patients or my family. So, take you want. On that front, uh, anything else topically, Evan, that you find a benefit with on your skin? That you're using yourself.
Evan Brand: Yeah, I've been playing with a couple of peptide creams. So there's some discussion about these.
It's hard to find good papers on it. And now the FDA is starting to maybe classify some peptides. So I don't know if some things are changing there, but you know, personally. Uh, topically, I've just messed with some hyaluronic acid, some topicals that have like some jojoba oil or some shea butter. I've messed with a few different things.
I like all of it. I think you're, you're right when you talk about moisturizer being the key because even if it's just lotion, even just a good organic, clean, shea butter based lotion, that even seems to help my skin just feel better, feel more supple, feel like Less wrinkle prone, less wrinkle producing.
So, I think a lot of people just are dehydrated from overusing soap on their face as well. People that are doing excessive cleansers, and then they do the soap, and then they do this, and then these ladies that have multiple layers of makeup. I mean, that's gotta be stripping you, is my assumption. Yeah, I
Dr. Justin Marchegiani: mean, you can go look at cars that are left outside versus a car that's stored inside, and you go look at the the inside dash leather.
And what that happens over years, it gets ripped up, right? So, doesn't mean you shouldn't get light, just don't get burned, right? And then use good quality antioxidants and things that hydrate the skin. Um, plus things like Emoil have a natural SPF of about eight, which is about an 80, 85, 88 percent SPF protection.
And so if you're outside for 30 minutes to 45 minutes, it's going to provide some pretty good protection as well, but also hydrate and still allow you to get some. ultraviolet light in there to help your skin, which is still important. Evan
Evan Brand: Brand That's cool.
Dr. Justin Marchegiani: Yeah. Dr. Justin Marchegiani We still want to burn.
Evan
Evan Brand: Brand Yeah. So somebody commented vitamin C and glycine. They take that and it helps. Yeah, for sure. Yeah. I mean, any amino acid formula, glycine, and we'll use if we're doing like a grass fed whey protein or we'll do free form amino acids. Those are all great building blocks for the skin as well. So yeah, I think that's true.
Dr. Justin Marchegiani: Dr. Justin Marchegiani Yeah. And also, um, glycine is the major amino acid in collagen. So when you're talking about glycine, I'm always like, well, let's get that from collagen. That's a great way to do it. Plus, vitamin C plays a major role with, um, with collagen, right? Vitamin C not only helps form collagen, but it stabilizes the collagen molecule, right?
So, having some extra vitamin C when you're taking in collagen, or, you know, at least taking a couple grams a day, a gram or two a day, at least that's gonna be helpful, um, so I like that. Plus, that's gonna also help with, you know, the ultraviolet light on your skin, you're gonna get some oxidative damage there, and vitamin C is gonna really help neutralize that damage.
So, you're not. destroying the skin and creating free radical damage on the skin, really keep the elasticity up. So, vitamin C, glycine from collagen is best, um, good healthy fatty acids in your diet, not the the seed oils or the rancid vegetable oils, because they're gonna actually be oxidized, which is gonna suck your vitamin C and your antioxidant reserves out.
So, you want oils that are gonna be more stable, cold pressed olive, avocado, and healthy saturated fats from coconuts, grass fed beef, your tallows. Dr. Justin Marchegiani
Evan Brand: Let's look at one more case real quick. This is a guy who is in his 50s now, and one of his major complaints was digestive issues, but he also said he had skin issues.
If you can pull this up for people, I just want people to see that. There's many, many different flavors of dysbiosis. So you'll see he pulled up here enterohemorrhagic E. coli on page one, more H. pylori on page two. About 51 percent of the world population has this infection. So keep in mind that this is not a rare problem here.
You saw his keystone bacteria were actually decent. There wasn't a ton of issue there, but then more dysbiotic. issues. I mean, including Klebsiella here, which is no good, Enterobacter candida even showed up a hundred X. So this guy's got a major problem here with his gut. And then if you look at the collateral damage down here, you'll see that his pancreas is just not working very well.
The elastase is too low, IgA is too low. So this is what. digestive and or skin issues look like on paper just from one stool test. And that's not even looking at the oat or anything else right now. Dr.
Dr. Justin Marchegiani: Justin Marchegiani Wow, that's crazy. Now, when we look at some of the, the oat organic acids that show like colonized mold, right, these are going to be like, I think, number two or five.
It's going to be, yeah, so you're going to see two He's got a big problem, by the way. Yeah, so that's a lot of call it now. So, with that, is that the environmental mold? Just to be clear, that's the environmental mold that he's being exposed to in the environment colonizing in the gut,
Evan Brand: correct? Definitely, and this guy lives in Romania.
And so, he says that all the houses there are hundreds and hundreds of years old. He lives in like a very, very ancient city. And so, who knows, uh, what this guy's been exposed to in his life. But it's very rare for me to see tartaric acid above 100, but you can see here number six, and for instance, he's aspergillus.
Anything above 5. 3 is bad, he's a 110. That's ridiculous. Dr. Justin Marchegiani
Dr. Justin Marchegiani: So when you see this, right? You're saying, Oh, okay. We have some colonized mold. We have to look at the environment. We have to get the environment clean, but we also have to then clean out the gut. We're going to be using botanicals to knock down the colonized mold in the gut, but maybe also some binders too.
Like maybe some like fulvic minerals and some zeolite and things like that too.
Evan Brand: Yeah, and the cool thing is the herbs that we're going to use for the bacteria are also going to address the mold as well. So that's the fun part about doing this is that the synergistic effect of herbs, we can use antifungal herbs that also might have antimicrobial properties.
So like Pau de Arco, French tarragon, thyme, all these herbal antifungals that we use. They knock out bacteria, too, so I told him we're gonna try to do a one two punch because as you saw in the GI map, we've got major autoimmune risk now. We've got Klebsiella sky high, and now we've got sky high mold colonization, so the next step, too, is to try to test the environment.
So we're gonna get this guy some petri dishes. He thinks he knows where the mold is coming from. Dr. Justin Marchegiani
Dr. Justin Marchegiani: And also too is like we may not want to do any nebulized glutathione until we have the internal colonized mold address as well. So people talk about using nebulized glutathione. I like it if we have a lot of breathing or lung inflammation, but let's make sure we get the colonized mold down first and then we can do that.
But internally, we're probably okay. Dr. Justin Marchegiani
Evan Brand: Yeah, I agree. And even our, the, one of the manufacturers we use, they have a big warning label about that. Don't put glutathione into your lungs unless you fix this issue first. And you'll see here, sky high candida overgrowth as well. So when we're talking skin issues, it's usually not one thing.
Everybody's looking for like either the magic pill, the magic potion, the magic lotion, like the magic topical. How do I fix my skin and look like a beautiful celebrity? It's really, it doesn't work that way. Cause look here. I mean, we see now there's major candida. We've got Aspergillus sky high. We've got tons of bacteria in the gut.
So there's five, six, seven infections all adding up to create this guy's problem. Dr.
Dr. Justin Marchegiani: Justin Marchegiani Yeah. Be careful of functional medicine or a natural people that are like marketing things as one thing. Don't get me wrong. People are searching one thing. So as a doctor, you want to have things that are keyworded that will reach.
those, um, keywords that people are talking about. But, hey, it's this one thing. But also, we have to look at everything else, too, because that can also be a thing in that list. So, just be mindful when you see people that, oh, it's just lime, or it's just mold. Well, we just talked about how the gut can be a mold factory.
So, even if you think it's just mold, and mold really is the issue, what if the gut's now colonized? So, you can't ignore that aspect, and that's just those, that's just the gut. What about, now, what about the hormones? What about detoxification? What about absorption? So, there's so many other, you know, let's just say, you know, it's a spiderweb.
One web gets hit and everything else starts to ripple, so you really have to deal with the ripple effect as well. Well
Evan Brand: said. And the truth is, just the H. pylori alone in his case could have created all of his issues in regards to digestive health and his skin issues, but as you see, a lot of times it's more complicated.
Let's scroll ahead just for fun, just to see. What other kind of collateral damage has happened here? I mean, clearly you see there's a lot of mitochondrial dysfunction. That's not pretty at all. Probably the mold doing that. Brain chemistry looks wacky. Look how low his serotonin is. He was saying he's definitely anxious and he's worried all the time.
Look at the endorphins. That's terrible. Dr. Justin Marchegiani 100%. Evan Brand Let's look at nutrients just for fun. Nutrients weren't bad. Isn't that surprising? Like his gut is so bad, but on paper, nutrient levels were okay. Dr. Justin Marchegiani How good is his diet? Evan Brand He's eating amazing. I mean, this guy lives in Romania.
He's got incredible pasture raised goats and. All the fresh veggies you can get exposed to and fresh fruit. I mean, this dude's like, living at a farmer's market. So. Dr. Justin Marchegiani So that's the reason
Dr. Justin Marchegiani: why he's not totally crushed. If he had like a standard American diet, we'd have, we'd have big problems.
Evan Brand
Evan Brand: Yeah. It's, it's kind of amazing. He was telling me how he took a trip from Romania to America and his gut just got even worse. He's like, I tried to eat healthy. He's like, I couldn't do it. Dr. Justin Marchegiani It's
Dr. Justin Marchegiani: the glyphosate. It's the glyphosate probably. Evan Brand Yeah. Dr. Justin Marchegiani Unless he's really fully eating organic.
I know glyphosate can rip up your gut. Yep. So I think we're hitting a lot of the big things here. I mean, just the people listening, there's a lot of things happening. So with skin, we have ways to topically hit the skin. We have red light. We have getting natural light. Don't burn. We have natural oils to help build up the integrity, keep our skin moist.
We have topical things to help get to the not so Nice bacteria off our skin. Uh, of course we have collagen. We have all the nutrients, the vitamin C to build up the vitamin A to build up the natural building blocks of our skin. Of course, all those building blocks get absorbed through the gut. So if we have gut issues, if we have low stomach acid, low enzymes, let's say we're a female that has a bi, a gallbladder removed and we don't have bile, that's gonna impact all those fat soluble vitamins.
Also estrogen. progesterone. You start getting more perimenopausal as a female. Progesterone's dropping, estrogen's dropping. That plays a big role with the elasticity of the skin as well. So you want to look at the hormones, the gut, uh, topical routines. You want to look at absorption. You want to look at mold.
You want to look at, um, bugs. All these different things could be a big issue. And then of course, if we're seeing autoimmune stuff, psoriasis, eczema, rosacea, um, maybe even perioral dermatitis, we gotta look more at the immune system. And of course, 80 percent of it lives where? In the gut, so it all comes back to the gut when it comes to the skin, even if we have autoimmune stuff, or even if we have microbial based stuff like on the acne side, we always gotta look back to the gut.
Evan Brand: Evan Brand Well said, and don't ignore your kids. If your kids have skin issues, maybe they're embarrassed, they're pre teen, teenager, they're having skin issues, their friends are, you know, maybe they're getting bullied, their friends are not real friends, they're making fun of them, they're having self confidence issues, I mean, I push through all that.
Because I didn't know this stuff when I was 15, and I had bad skin issues, but with this, with the information in the labs now, there's really no excuse to let these kids walk around with a pizza face, so if your kid is suffering from that, like, severe cystic, deep, scarring acne, let's try to, let's try to get a grip on that as soon as we can, and you guys can reach out worldwide, Consultations are available.
So if you'll pull up our, our websites, we never do this, but we need to, we need to show people a visual here. Some people are visual learners. So if you'll pull this screen up, let's show people the sites here. So here's Dr. J site here, justinhealth. com. There's that handsome guy right there. You could click here, make an appointment.
And then there's also an amazing opportunity to get access to emails. And we have newsletters and we have special opportunities and special things that we don't publish here. So you could definitely opt in right here. and what you're interested in. But this is Dr. J's site here. You'll see more content, thyroid books coming.
Excited about that. Check out the health store. So that's Dr. J. Worldwide consults available. More, uh, FAQs, things like that here for the clinical side. And all the supplements are also available here in this beautiful menu. And then my site right here, evanbrand. com. And we'd love the ability to help you.
So, You can go here. I've got courses as well. Consultations. Check it out. We'd love to have you guys and we'd love to help you. We'd love the opportunity to do it. So we've got a lot of good content. We've got good teams behind us here to help you guys and help you get better.
Dr. Justin Marchegiani: I love that. Very good. And I just, you know, I follow a lot of stuff online myself because I'm always trying to get ideas.
I feel like the information we put out is very actionable. I think a lot of people's content is more theoretical. Right? It's like, hey, this, this sounds good. This is good. But hey, does it actually work in the trenches? Right? And so, this is actually clinically proven stuff. You know, we've seen 5, 000 plus patients on my side, 15 years.
You've been seeing patients for well over a decade, thousands of patients. So, we're in the trenches. You know, we're talking tens of thousands of patient hours over the last, you know, 25 years between each of us. So, if you want to dive in, let us know. Put your comments below in it. You have family or friends that are suffering from these issues.
Send this podcast over. Let them know. Give them a share. We really appreciate it. Evan Brand
Evan Brand: Yeah. And you know what's crazy, too? I see this on YouTube a lot now. There's these N equals one channels, these N equals one experiments that go viral. So, the YouTube title will be something like, this guy spent 30, 000 to biohack his gut or This lady, she did this to extend her, um, her telomeres or, and so there's all these like zoom ins on one particular person, but it's like, you have no idea about their childhood.
Where did they grow up? Did they have farm exposure? What kind of chemicals and toxins did they get from their mother? So to, to really like idolize these key figures, I don't really seek that in people. I don't really seek. To be an idol like that. I mean, I've been through hell and back. Um, you've been through some health challenges and you've been able to improve your health as well.
So, so I'm not seeking to be this, this, this little keystone in equals one for people. I think what you and I offer that's even more valuable than that is. All of the clinical experience, because you could follow everything that guy's doing on YouTube and you follow his exact 250 step biohacking protocol, his day in a life sunrise, this and grounding this and in the hyperbaric this and you're, you're no better off.
And you're going to spend tens and tens of thousands to try and like hack and mimic the lifestyle you're seeing. And so I just want people to understand that as wellness becomes trendy and as wellness becomes sexy and it's a very visual thing. Here's this amazing sauna room, this amazing biohacking den and this 20, 000 bed.
Those steps could be a distraction from just doing. What we call simple foundational labs. Mm-hmm . Like organic acid testing. Mm-hmm . So please don't get caught up in that. I saw a video pop up on my YouTube today, and it's like, here's how this lady, uh, looks 30 years younger than her friends, and it's hundreds of thousands of dollars to do all the treatments she's done.
The facial, this, the, the, the needles here. Like, it's crazy.
Dr. Justin Marchegiani: I agree. And someone in the said, well, hey, um, what can I do to get some of the information that you guys have? I said, well, first off. Check out the podcast and videos. It's free. Secondly, Evan's got some great courses. So feel free to sign up for Evan's courses.
I have a book coming out. It'll be out either this month or next. It's in the final round of edits done. When you have a book and you have a hundred images, it takes so long to have those images edited and dialed in and the DPI and the height and the ratios, all that. So all that stuff's done. And I'm going to have a course coming out as well.
That'll kind of supplement the book. So. Start with the free stuff and share with friends and family. And then we have some paid content that you can dive in with Evans courses, my courses in my book as well. So. Take a look at that. Awesome. Well, you
Evan Brand: guys take good care. We appreciate the comments here. Guy said that, uh, the, this channel is one of the only YouTube channels that gets to the bottom of the issues without the BS.
Yeah. I mean, look, we don't have time for that. We, we got kids, we have clients to see. We don't have time to just like, will you, and, and, and wow you with all these visuals. We need to get you the nitty gritty data. That's really going to help make a difference in your life. That's what we're here to do.
Dr. Justin Marchegiani: Absolutely.
Evan Brand: Well, appreciate you all
Dr. Justin Marchegiani: listening and enjoying the content. Take care of y'all. Peace.
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