In this episode of Beyond Wellness Radio, Dr. Justin Marchegiani and Evan Brand discuss five hidden parasite symptoms doctors often miss, including brain fog, fatigue, digestive issues, and anxiety. While parasites are commonly associated with diarrhea or stomach problems, many infections present with subtle symptoms that affect energy, mood, skin, and overall health.
They also explain why parasites are frequently overlooked in conventional medicine, how gut infections can coexist with bacterial and fungal imbalances, and why advanced stool testing is often necessary to properly identify hidden gut infections. This episode explores how parasites impact gut health, nutrient absorption, the immune system, and the gut-brain connection.
• Parasites are more common than many doctors realize, even in developed countries.
• Hidden parasite symptoms can include brain fog, fatigue, anxiety, and digestive problems.
• Parasites often coexist with other gut infections like SIBO, candida, and H. pylori.
• Chronic gut infections can contribute to inflammation, immune activation, and nutrient deficiencies.
• Proper stool testing can help identify hidden gut infections and guide treatment.
• Parasites may contribute to symptoms such as brain fog, fatigue, skin problems, and sleep disturbances.
• Many parasite infections are missed with conventional stool testing methods.
• Advanced stool testing can identify parasites, bacteria, yeast, and other gut imbalances.
• Parasites can interfere with nutrient absorption and contribute to deficiencies like iron and B vitamins.
• Addressing gut health and restoring the microbiome is often necessary to fully resolve parasite infections.
Dr. Justin Marchegiani: [00:00:00] Hey, and we are live. It's Dr. Jay in the house with Evan Brand. Today we're gonna be talking about the five hidden parasite symptoms that we see clinically that most doctors miss. We're gonna dive into this topic today. Evan, how are you doing today, man?
Evan Brand: Doing good. I can't complain. I had parasites years ago.
Y'all probably heard my story on that. I had giardia and crypto. I lost 30 pounds without trying, I had just random bouts of anxiety. Mm-hmm. My skin wasn't good. So, yeah. Uh, I've had personal experience and we've both had a ton of clinical experience with this stuff.
Dr. Justin Marchegiani: What were the big parasites that you had? Let's just kind of talk about our own personal experiences with gut stuff and parasites first.
What were the big ones you had? I remember it was the three amigos, but go ahead.
Evan Brand: I had Giardia and crypto. And then along with that h pylori I, so technically two parasites, one bacteria, and yeah, I had a lot of issues, a lot of weight loss that was uncontrollable and I didn't know what the heck was going on.
Dr. Justin Marchegiani: Yeah, no. And so we had what crypto, you said GII and h pylori. Right. What were some of the big symptoms that you had personally had?
Evan Brand: The weight [00:01:00] loss was big skin, mood, sleep. I mean, it was all disrupted.
Dr. Justin Marchegiani: And I remember also too, there was some blood sugar stuff. You were getting dizzy and lightheaded after meals, right?
Yeah. Those are some kind of uncommon symptoms, but they happen right?
Evan Brand: Yeah, well, I mean, I had mold, I had Lyme. So once you pile up the functional medicine issues, it can start to get confusing. And this is why it's important to get the data so you can tease apart what's actually going wrong and not just guess.
'cause a lot of people are doing parasite cleanses and they have no idea what they're up against and they're not even testing, they're just buying some random TikTok cleanse. Then they wonder why they feel bad and then they stop taking it. It's this whole thing now.
Dr. Justin Marchegiani: And here's the big thing that I see functional medicine wise, right?
And this is what you learn with thousands of patients experience. And this is what, you're not gonna get this from chat GBT. You're not gonna get this from like what you kinda, the general parasite cleanse online when you have gut infections and gut micro. You more than likely have an array of different things.
It's very rarely [00:02:00] just one thing. The biggest assumption most patients make is they think it's just one thing that they just get this thing, everything unlocks. It's typically not that simple. You know, when someone who has a very acute issue, right? Maybe it can be that simple, but the most people that we see, there's a more of a chronic health implication.
With everything going on, there's usually a lot of things happening. So maybe there's some gut stuff, maybe there's some mental health stuff, brain fog, anxiety, depression, um, energy focus issues. Lethargy. Then there may be some IBS symptoms too, right? Bloating, gas, constipation, motility support. And a lot of times when you come in and you just start blasting microbes out in the gut, a lot of times you can feel worse because you've not fixed, you've not set the underlying milieu.
Especially if the hormones have been beaten up for a while. Hormones are a really important trigger to help your body become anabolic, to heal and recover. And so just going in and blowing stuff up, you still don't have this anabolic environment where your immune system's healthy, where you're absorbing nutrients, where your gut lining integrity is good, where you have [00:03:00] a lot of nutrient density over the last months and years, and so then you, it's like you drop bombs, but then you can't get the carpenters in to help work on healing and repairing.
Evan Brand: Yeah. Yeah. This is a common story. I'd say out of every a hundred people we test, we'll probably see half or so have parasites. Mm-hmm. I think it depends on the year. And truthfully, it depends on our content. I mean, sometimes if we're talking more about parasites, we get a a surge of parasite clients that have already failed with other providers.
And so I would just say in general, it's more common than you think, and you do not have to leave United States to get parasites. This idea that you have to travel to a tropical country. It's not true. Look at your pineapple from Costa Rica. Look at your blueberries from another country. Look at your meat from another country.
Your grass fed meat at Whole Foods. They're shipping it in from Argentina. It's like, okay, so the whole food supply is international these days. You do not have to be a world traveler to get parasites
Dr. Justin Marchegiani: and also too many. Patients, they kind of, they take the [00:04:00] functional medicine principles and the philosophies.
They kind of already been failed by conventional medicines. First off, conventional medicine doesn't really acknowledge parasites being an issue. They kind of say, this is a third world kind of thing, right? You see like the starving kids in Africa with the. With the quai workers kind of belly and all the, the diarrhea and the AIC dysentery, right?
They're like that, that's a third world issue. And they think, ah, that's not really a problem here. One the wrong, we see it all the time. But two, you can have other gut dysfunction where it may not just be a parasite by itself, it may be a parasite with something else going on. Plus the testing that we run, we run some of the PCR genetic testing on the stool and, and we may see parasites that are borderline, that are not even at threshold.
They're not even at a high level. So let's say Giardia require, or let's say blasto requires 10,000 cells to be considered positive. It may be at one or 2000 cells is at a high enough level where it could be creating some problems. And the problem with conventional testing, usually it's gonna have a stain on it, and then there's a microscope where you're looking at it visually, and it has to be at a high enough level.[00:05:00]
To see it there, right? But with the PCR, we can test a little bit more in a sensitive manner, but you know, we'll see people that have blasto at a lower level, maybe not positive or GII at a lower level, not positive. So now how does that person get picked up? By conventional medicine, they, they don't, they, they falls at the cracks, but now what if it's very low and then they have SIBO or high levels of citrobacter or pseudomonas or marella.
Maybe they have candida, nh pylori, maybe they have a lot of gut inflammation. Their calprotectin is really high. Maybe their immunoglobulin A is either very high or very low. So their immune system is overly stressed or overly depleted, and maybe they have low elastase, so low enzymes, low acids, maybe that's also creating a biliary insufficiency, not a bile.
So they're not emulsifying breaking down their fat. And then here we are. And so it's, you can't just drop a bomb and all the other collateral damage just reverses. And so that's the biggest mistake. Most people make coming in, they just take the the conventional medicine philosophy and they apply a functional medicine intervention.
So here's the one-off thing. Instead of doing this thing [00:06:00] conventional medicine wise, now we're gonna do this thing functional medicine wise. And we just think it's all gonna heal and not that simple.
Evan Brand: Yeah, yeah. Well said. Let's pull up a GI real quick if we're gonna, uh. Talk about the, the biomarkers. This case here, I just wanted to show off page four 'cause you're bringing up a lot of important stuff on the intestinal health side, which is, yep.
What is the collateral damage based on the infection load? And you can see here this guy had low pancreatic elastase. Look at the occult blood outta 63. This is horrible. Gut inflammation. Calprotectin is a 9 9 9 97. That's terrifying.
Dr. Justin Marchegiani: Holy smokes.
Evan Brand: I know, I know. This looks like to me an autoimmune issue.
Ulcerative colitis or Crohn's? Probably a hundred percent. Yeah, I mean, look at this activation protein we've got here too. So the gut is clearly, clearly under attack and, and what can happen with these infection loads is they will create this runaway train effect with your gut inflammation. So I just encourage you, uh, if you're getting put on some sort of an inflammatory.
[00:07:00] Modulating or immune modulating, like immune suppressant medication. You gotta be careful with that stuff because you're not fixing these bugs. If you fix these bugs, you know that's what's actually going on. And the inflammation will get lower by clearing the bugs. But this idea of getting put on these chemo drugs and some other stuff, I, I've seen some scary conventional protocols.
Dr. Justin Marchegiani: Alright, so lemme just pull up a couple things I wanna highlight here for y'all listening at home.
These are a couple things that we see here, right? So some big symptoms that we see, the, the five big symptoms we see other doctors just miss it. It's, it's very, very frequent. But number one, we're gonna see brain fog. That's a common one. And this is big because when you have brain fog or anxiety, now who are you seeing?
If you're in the conventional medical system, now you're seeing a therapist, now you're seeing a psychologist or a psychiatrist. And then now what? So now your chance of being put on other drugs that mask those symptoms that don't get to the root cause goes up. And I tell patients. All the time. I'm not anticon conventional medicine or anti-drug.
I'm pro root cause. And so [00:08:00] you, you know, walk me through how we're getting to the root cause most of the time when we go conventional medicine, we're not, uh, fatigue. So of course other nutrient deficiencies, whether it's vitamin C, whether it's B vitamin issues, whether it's things that impact the mitochondria, nutrients that plug into the thyroid, nutrients that plug into the adrenals.
Um, important co-factors and enzymes to help make our female or male hormones and of course skin stuff. People think about skin and they go to the conventional dermatologist. They're given retinol or retinoids or tretinoin, Accutane, tetracycline, clindamycin, different, all these different topical things and metrogel, and they're not really fixing the underlying issue.
Comments on that, Evan?
Evan Brand: Yeah. Well, it's just they're looking for a quick fix and unfortunately this thing takes potentially months to clear up. And
Dr. Justin Marchegiani: yeah,
Evan Brand: the other variable is if you have mold. You can also develop somewhat of an immune suppressant effect from the mold, the mycotoxins, and I think you're gonna be more susceptible to picking up bugs.
That was my story as well. So I find [00:09:00] that if people just do parasite cleanses, they don't dig deeper into the immunity, then they're gonna continue to spin their wheels.
Dr. Justin Marchegiani: 110%. Now, a couple things here, right? My lab test normal, I feel off, right? These are big questions. Why do I have these symptoms? No one can explain it, right?
Why do my gut issues keep coming back? And a lot of times there's something else going on. This is kind of cool because it, it really gives you that impact of how these parasites, they kind of adhesed into that gut lining. They kind of stick. That's kind of how they hang out, right? They attach to the intestinal tract.
They, they activate a lot of the immune cells. So now we're having histamine. Now we're having neutrophil activation. Eosinophil activation, right? Eosinophils. We'll see those go high. On A C, B, C, right? Eosinophils, EEE, for allergies or parasites. And people are like, well, I have mast cell activation syndrome, right?
MCAS. And it's like, well, what's the root cause of why your mast cells are an overdrive? Why is your immune cells overstimulated? Because MCAS, a lot of times for. [00:10:00] It doesn't speak to what the root cause is. Is it a mold issue? Is it a combination of food allergens? Did you have a bunch of glyphosate exposure over many years that it wiped out your gut lining?
Is your gut really permeable and you lots of food allergens? Do you have infections? And so we have to speak to the underlying issue. And many people, when they're describing their issues or their symptoms, they're speaking about things that are downstream, not upstream.
Evan Brand: Yep.
Dr. Justin Marchegiani: So big thing out of the gate, right?
IBS, bloating, food sensitivities, fatigue, brain stuff, anxiety. That's gonna be number one. Next one, we have our nutrient theft. Okay? Big things you wanna highlight. When we have suppressed appetite, diarrhea, or let's say we just have malabsorption, let's say we're not breaking things down as well, that's gonna make it harder to absorb our protein, absorb our fat.
Now we have inflammation. So like that last person you showed on the GI map. They had lots of eosinophilic protein, EPX, they had lots of calprotectin. You could easily see anemia, whether it's a megaloblastic anemia, where your red blood cells and your hemoglobin go big, and [00:11:00] that's a B vitamin issue.
Typically B12 folate and B six. Or it could be more of a, uh, microcytic, hypochromic anemia, which is more iron. These are pretty darn common. Comments on that.
Evan Brand: Yeah. Hair loss too. So ladies, you're gonna blame your hormones or your hairdresser's gonna say, Hey, maybe you need to do this or that. But if you improve your gut, your hair will magically start to grow.
My wife gets compliments on her hair all the time. People are like, how is her hair
Dr. Justin Marchegiani: so long? It's crazy.
Evan Brand: Yeah. People are like, how is that not hair extensions? And I would credit working on her gut. And then also organs. I, I think the organ capsules have really helped.
Dr. Justin Marchegiani: Well, organs are just notoriously high in copper, which is really good for the hair.
Zinc, which is really good for the hair. Of course, you need iron and B vitamins. Um, biotin, B seven. Really important for the hair. Anytime I see chronic hair loss outside of just looking at androgenic alopecia, which can be a big thing, elevated DHT in that alpha reductase enzyme in men or perimenopause.
[00:12:00] Menopause. Low progesterone, low estrogen in women. The gut plays a such a big role in hair. You have to get the protein in there, right? Your hair is mostly keratin protein. You need those building blocks.
Evan Brand: Yeah.
Dr. Justin Marchegiani: Alright. Next is overactive immune system. So we see lots of patients have one. They have gut permeability, leaky gut, they have the intersite kind of opening up.
If you will, and those opened up in Enterocytes. Well, we have these toll-like receptor sites. These are the centurion guard. They sit guard in front of these enterocytes and they're constantly sensing the environment, whether it's viruses or bacteria or lipopolysaccharide or food allergens. And they're gonna sense and, and provide the input to that zonulin protein to go up or down.
And when that zonulin protein goes up, that's gonna unzip that tight junction, those enterocytes, and allow those different microbes or food in, and that's gonna over activate the immune system. You can see what happens, right? We have our CD four, our help, our helper cells. Over here we have our different interleukins.
Here's our eosinophils, here's our basophils. Remember, our basils are, um, become mast cells in the [00:13:00] tissue. And what do mast cells produce? Histamine. So someone's saying, I got histamine problems. I got mast cell activation syndrome, right? It's like, well, yeah. So that's downstream. Let's go upstream to what the actual trigger is.
You can see all these different interleukins and everything. And that laminate propria, that's just the, that first lining in these small intestine right there. And then you could see all the mucin things like Akkermansia help with this. And, and then you could see these different microbes. These are helmets, for instance, type of, um, worm.
And that's actually causing tissue damage and allowing that gut permeability to happen. And so we'll see more eosinophils. We'll have this more TH two immune response. TH one, TH two, TH one's. The cytotoxic immune response. That's your natural killer cells, which are your CD eight, your helper cells, CD four.
Right? Think of these as the frontline special forces. Of your immune system. And then you have your th two, which are gonna be your antibodies that are the infantry that come after the fact. Um, this is gonna be your th two. You'll have more histamine release. And this, we can also see more skin rashes, itching, we're gonna see more sinus congestion, [00:14:00] and maybe even more allergy like symptoms outta the gate.
Evan Brand: Yeah, so this is why we'll factor in some herbal, natural histamine supports into the protocol because you are basically, you're basically on fire, if you will, from an immune perspective. Correct. And, and you're gonna overreact to everything. So that could be more food sensitivities, like you're gonna react to higher histamine foods, such as avocado.
It could be you're overreacting to peppers, tomatoes. So a lot of people need to go on a low histamine diet while we're working on the gut to improve their health. So I don't think it's forever, but I think for a month you should try to go low histamine, see how much better you feel, and then we'll come in with some natural histamine supports, try to stabilize the mast cells while we're clearing out the bugs.
That's generally what we have to do. A
Dr. Justin Marchegiani: hundred percent. Alright, so big things outta the gate. I wanna highlight now, gut brain access. This is a big deal here. This is, this is big. I wanna zoom in on this if you don't mind. So outta the gate, we have our brain, we have our spinal cord. This is part of our central nervous system.
And then we have [00:15:00] our auto autonomic nervous system. And then part of that is parasympathetic, sympathetic, and then autonomic, the parasympathetic comes down via the brainstem. This is the vagus nerve here. This is the spinal cord, but you have this vagus nerve. You don't really see it, but it, it comes through and it wanders throughout the whole organs, right?
Vagus literally translates to wanderer. And so you can see you have this HPA axis kind of feedback loop. So our pituitary hypothalamus here, hypothalamus pituitary, that feedback loop via cortisol, cort tropic releasing hormone than adrenocorticotropic. Now we're at the adrenals, and then it goes cortisol next.
And that impacts the circulatory system. It's gonna impact, it's gonna be impacted by bacteria, cytokines, different microbial issues, food allergens, parasites. This is going to cause a cortisol response, and so the more cortisol you have over time, it actually can weaken the gut lining. So a chronic cortisol stress response, this h.
PA access goes into overdrive, and it can [00:16:00] also impact that lamina propria that we showed, that first gut lining layer, and it can actually make the gut go a lot more thin.
Evan Brand: Yeah. And this is more common in the modern day when you have microplastics and pesticides. Mm-hmm. And other things that are damaging the gut.
So maybe in historical times, we would've been able to coexist, have some level of parasitic infection and be fine. But I think with the modern world's toxicity that it presents, we just have too much in our buckets to handle this anymore. So people ask, well, parasites have been around forever. Why does it matter now?
And my. Answer to that is, well, we have a lot more on our plates. We have a lot more on our immune system that we didn't have even just a couple hundred years ago.
Dr. Justin Marchegiani: Yeah. And also people would pass away all the time before antibiotics were created, man, people would pass away all the time. Obviously we know the key with parasites is clean food and water.
Like, like don't, don't poop and pee where you live and make sure you have clean water source. So that fixes like, you know the, the Guyer studies, right? Guyer is a public health. [00:17:00] Epidemiologist researcher, and he, he found that 70 to 80% of our health just, just coming from clean water, clean food, having good, you know, sewage and sanitation practices, fixes most of the problems.
Now, there's a feedback loop here, right? Look at this. You have efferent nerve inputs and afferent nerve input. Afferent means essentially. Aernt is gonna be nerve input back from the intestines back to the brain. So it's like, it's the sensor telling you what the temperature is, and then you can see the temperature and then the efferent is gonna be the nerve input that that carries out what the brain wants it to do.
So brain to the organ is gonna be efferent, efferent is going back up, back up. It's telling it where it's at. And so you could see all the different inflammation here, T cells, B cells, uh, again, we just say. Inflammation overdrive based on the immune system. That's what's happening here.
Evan Brand: Yeah.
Dr. Justin Marchegiani: Um, that's, and then let's just kind of talk page
Evan Brand: four.
So page four of your gi when you get this done mm-hmm. This is
Dr. Justin Marchegiani: why we
Evan Brand: want y all to test not guess with your health is because when you get a GI panel, you're gonna see the [00:18:00] calprotectin level. And so this is just helping you to understand some of the, the geekiness behind it. But what you need to know is the number of your calprotectin.
Even conventional GI doctors recognize calprotectin as a marker. They just use drugs to suppress the inflammation rather than clear the infection. Now they can use, you know, we didn't talk about this, but they can use conventional drugs to kill parasites and they can be very effective, but I have a bias towards the natural stuff.
Dr. Justin Marchegiani: A hundred percent. Now out of the gate, you're gonna see here neuroinflammation. This plays a big role. 'cause like the, one of the big symptoms that your Dr. May miss is inflammation in the brain, right? Inflammation in the brain is a big deal because you're gonna come in with anxiety, depression, brain fog, cognitive issues.
You're gonna be complaining and if you have a gut issue. Your, your GI doctor is not gonna recognize any of this as being connected to the gut, and that's a big deal. And of course, the more cortisol we have, right, the more that impacts the blood-brain barrier. When that [00:19:00] blood-brain barrier, this is known as astrocytes.
When that those astrocytes are depleted. It's gonna allow microglial activation. So now we have the inflammation in the immune system is the immune system is overreacting now to inflammation due to that blood-brain barrier being depleted. And so when those microglial cells are activated, it's gonna show up as brain fog and mood issues.
And we really just have to get to the reason why this blood-brain barrier is permeable and it starts in the gut, right? Get this intestinal inflammation better. It's gonna help because inflammation is bidirectional. That means inflammation in the brain, right? Or in the body. Stress in the body can impact the gut.
We know that because if you have trauma or if you get stress, we know your digestion gets crummy. But inflammation here with different microbes can also allow inflammation to sit, come out, and the impact of blood brain barrier, and then create all these other symptoms.
Evan Brand: Yeah, I had it. I went through it. So I can tell you with confidence, your mood will get better.
And you know, there's people on antidepressants right now, anti-anxiety medication that have some level of dysbiosis, which could include [00:20:00] parasites, bacteria, fungal infections, yeast. And if they clear that up, their mood issues will completely go away. Which,
Dr. Justin Marchegiani: yep,
Evan Brand: the pharmaceutical industrial complex would like you to be a lifelong customer of an S-S-R-I-S-N-R-I and these other meds, but.
I just prefer to fix the gut and watch the mood heal, and you can save your, save your marriage with this stuff, I mean, truthfully. Yep.
Dr. Justin Marchegiani: I wanted to highlight one thing here. This one, sleep disturbances. Parasites have opposite waken sleep cycles than we do, and so they may be up and more active at nighttime, and that can create more inflammation.
And guess what happens when you create more inflammation? What's happening to your adrenals in your cortisol rhythm? It may be going up at night, and if your cortisol is going up at night a little bit or it's it's disrupted, guess what that can do to your wake? It can make your sleep less restorative. It can impact your HRV and your readiness scores, but it could also just wake you up because it's overstimulating you.
That cortisol response [00:21:00] is creating a bunch of adrenaline and blood sugar, and you're getting mobilized and you're feeling alert, and it could be from a parasite issue. It's definitely possible.
Evan Brand: Yeah,
Dr. Justin Marchegiani: comments on that?
Evan Brand: Well, uh, I think with the herbal anti-parasitics, most people can resolve this in a few months.
So just to give you a timeline. I have seen some cases that take six months, but I would say in general plan for three months to really start to clear this out. And there's different herbs that we use for different bugs. So most people have heard of oregano oil, which can be broad spectrum. Mm-hmm. It can be pretty hot.
Meaning, I don't like to use it if there's a lot of gut inflammation happening, right? But there's a bunch of others that we can rotate through. I think the ultimate answer for people, you know, maybe if you're glazing over this, some of this stuff, if it gets too geeky for you, here's what you need to know.
You need to know that. You can get the GI panel done at your home. You can get the results in two to three weeks to figure this out, because you may be resonating with some of [00:22:00] these symptoms and thinking, okay, do I have this or not? It's easy. One stool sample will give you the answer, and then depending on what shows up, we're gonna help you through designing a protocol.
But oregano oils not all inclusive, like that is not a full protocol. And just doing oregano or just doing garlic, for example. I don't wanna say you're destined to fail, but I don't think you're fully gonna resolve your issue. A
Dr. Justin Marchegiani: hundred percent. And then last thing here, just wanna move on, is um, blood sugar.
So the more cortisol and stress you have, the more that can increase glucose, right? The more stress and inflammation you have, you're actually mobilizing about 25 to 30 grams of glucose. Think of that as a Snickers bar. So the more stress that inflamed you are, each time that happens, you're gonna be getting a lot more glucose, like a Snickers bar equivalent, which people don't realize that.
And then lemme just kinda hit a couple thing here. We have two main types of parasites. We have our helmets, these are our parasitic worms, these are multicellular, and then we have our. Single cellular. These are gonna be like our, our protozoa. And so here, here are the ones. So helmets, parasitic worms.
These are multicellular round worms. Pin worms, [00:23:00] hook worms, whipworms, thread worms, right? A scariest lumoid, andous, foulis and cyclos. Stoma. Duodenal. Urus, RIA. Strong galois. Stir callus, right? These are our large multicellular worms, and we'll go into the meds real quick. Um, and then. Proto. These are our single cell ones.
Okay. This is gonna be Giardia. This is gonna be E histo, right? Tropho. These are gonna be regius crypto blasto, right? These are very common in modern PCR testing. And then one thing I get is like, oh, I'll just do an ivermectin cleanse. Well, number one, ivermectin works more on these helmets though, right?
And it, and it works primarily on. Strong Galois. So the thread worm. So that's the one that's gonna work the most on this guy right here. Strong galois. People think, oh, I'll just do an ivermectin lens. Well, it's, it doesn't do well on whipworm. It doesn't do well on pinworm and then a little bit on roundworm.
And so if you combine it ivermectin with usually a me bendle tends to be the best combination. But [00:24:00] again, see these parasite cleansers guys that's only working on helmets, right? That's not touching these. Protozoa that are single cell. So just be mindful of that. People, I've been seeing lots of stuff. I wanna do a parasite cleanse.
It's these two medications. You gotta combine 'em, but it's not touching these and it's not gonna touch sibo. It's not gonna touch h pylori, candida, or, or fix all the gut inflammation. So just be, be mindful of that.
Evan Brand: Yeah, it's, well, it's, it's kind of trendy, right? Yep. It's, it's becoming trendy. You're, you're seeing states now.
I think Florida actually just passed. We should be getting some over the counter ivermectin soon. So, you know, I think this is just driving more interest in it, but. I would agree that mm-hmm. You definitely want to have the natural stuff on hand as well. So Ivermectin, I mean, we could do a whole thing on the chemistry behind it.
It came from a group called Ivermectin and some of it was derived from the soil. So in a way it is natural, but I still think the, the true herbals, the clove, uh, the berberine, there's a lot of different tools that we use [00:25:00] depending on what you show up with. 'cause once again, we've alluded to this some today.
But it's very rare to have just a parasitic issue. Most of the time you're gonna have bacteria or yeast with it.
Dr. Justin Marchegiani: Correct. And how these medications work, Albendazole ole micro tubule formation. So blocks the parasite, uptaking, glucose, and there's some other, um, diseases that begin with a C and N with an R that have also shown to be very helpful with these conditions because it's blocking.
Uptake of glucose and it's supposedly, um, other types of conditions that start with a C and with an R also uptake glucose And these medications actually help in that way too, which is kind of interesting. Yeah. And then, um, same here, right? Ivermectin was a, a big thing a couple years ago, right? 'cause it has a, a.
Immune supporting antiviral impacts, but it causes neuromuscular paralysis. It, it basically opens up the parasite chloride channels and it overwhelms it. It also has zinc. I iono four qualities as well. So that's how that's working. And then we have some of the herbs that we use, right? We're using Artesia, we're doing black walnut.
We're doing. Ne [00:26:00] we're doing oregano, we're doing different berberine. We do a lot more other herbs besides this Artemesia wormwood. But again, we also have to make sure we support the microbiome, fix the overall function, just killing alone, the dose. And it's also a combination and a synergy of a lot of these herbs together.
Evan Brand: That's right.
Dr. Justin Marchegiani: Any comments in that, Evan?
Evan Brand: Yeah. One plus one sometimes equals three when it comes to these blends because of the different alkaloids and terpenes. And so sometimes uh, you'll take just oregano and it doesn't work. Or maybe it's too strong for you, so I just encourage
Dr. Justin Marchegiani: you Yeah.
Evan Brand: Get the data and don't just bomb your gut.
Dr. Justin Marchegiani: Yeah. And symptoms may be mild. You may have fatigue or brain fog. They may be chronic and subtle and you, your gastro may miss it 'cause it's not the typical chronic diarrhea. And so you, you gotta think a lot deeper about it. You can't just think that you, you have it so. Guys, if you're enjoying this podcast, right, feel free, share with family and friends.
Parasites aren't just the typical digestive issues that you know, bloating, gas, constipation, diarrhea. It can be deeper. Some of your chronic health issues that we mentioned here [00:27:00] today, cognitive mood, hair, skin, nails, can all be connected. Sleep can all be connected to it, so you definitely want to. Not guests.
You wanna assess, you wanna figure out what's going on with you. Take a look@evanbrand.com for Evan Evans, these patients worldwide. Myself, Dr. Jay, just in health.com, we've been doing this in the trenches, 15 years, 5,000 plus patient experience between each of us. Lot of experience. If you need that support, try stuff on your own.
We put a lots of free content out. 99% of the patients we reach PE people we reach with our content will never see us or meet us or work with us. And so we're helping more people than we are clinically. But if you want. To be in that top 1%. Take that next step. We're here for you, links and information down below.
Anything else, Evan?
Evan Brand: Yeah, well said. And that's true. I mean, a lot of the stuff we give you here can change your life, so hopefully you'll implement some of it, but more importantly, you'll, you'll get the drive and you'll get the motivation to know that there is a higher level to this game of life. And by improving digestion.
You improve your mood, [00:28:00] you improve your hair, your sleep. This is all about being a better version of you. So yes, it's important to catch the symptoms, like, oh, my gut hurts. But ultimately once you fix that, you're clearing the path to a higher level of living. Yeah. So I just encourage you to know like I was in.
The depths of hell at some points with my symptoms. Yep. And to come out of that, it makes you extremely grateful for every day. And just know that as you feel better, your gratitude, your happiness, all that stuff can be directly linked to, to clearing this stuff. So if you beat yourself up, you think that it's just like a personality defect or something you have, it's probably not it.
It's probably something like this.
Dr. Justin Marchegiani: Yeah, now I'll come back and do another podcast or a video kind of on some of these topics, so if people wanna come in with a live q and a, I'll be there for y'all. But yeah. Can parasites cause anxiety? Yes. Can they cause neurological issues like earring? Yes. Anytime you create immune activation or you impact the gut, that impacts electrolyte absorption, nutrient absorption, it impacts your adrenals, your thyroid, and so it has collateral damage downstream where it's [00:29:00] not like the direct thing.
The damage it causes upstream can trickle downstream to other nutrients, other problems, and those symptoms can manifest downstream for sure.
Evan Brand: Yep, well said.
Dr. Justin Marchegiani: So excellent podcast here you guys. If you enjoy it, like thumbs up, comments down below and we're here for you for additional support. Let our staff and team know links down below.
Alright guys, have an awesome day, Evan. Peace out brother. Take care. You too. Bye.
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